CN105106834A - Huoluo oil and preparation method thereof - Google Patents

Huoluo oil and preparation method thereof Download PDF

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CN105106834A
CN105106834A CN201510521914.7A CN201510521914A CN105106834A CN 105106834 A CN105106834 A CN 105106834A CN 201510521914 A CN201510521914 A CN 201510521914A CN 105106834 A CN105106834 A CN 105106834A
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huoluo
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CN105106834B (en
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戎钟洪
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Abstract

The invention relates to Huoluo oil and a preparation method thereof and belongs to the technical field of preparation of medicinal oils. The Huoluo oil is made from, by weight, 25-30 parts of rice fermentation product filtrate, 10-16 parts of argy wormwood leaf extract, 5-14 parts of safflower extract, 12-13 parts of Panax notoginseng root extract, 10-11 parts of garden balsam stem extract, 8-9 parts of gingko leaf extract, 6-7 parts of oat germ oil, 6-7 parts of red-rooted Salvia root extract, 5-6 parts of mint leaf oil, 4-5 parts of Chinese angelica root extract, and 3-4 parts of turmeric root oil. The Huoluo oil is prepared by subjecting the components above to pulverizing, soaking and special treatment. The Huoluo oil prepared by the preparation method has the effects of relaxing tendons and activating collaterals, dispelling wind-evil and eliminating stasis, warming meridians to dissipate cold, dispelling wind-evil and eliminating dampness, and promoting blood circulation to arrest pain; the Huoluo oil in a ball design is convenient and simple to use and convenient for drivers to use.

Description

A kind of HUOLUO YOU and preparation method thereof
Technical field
The present invention relates to a kind of HUOLUO YOU and preparation method thereof, be specifically related to a kind of employing pure natural plant ingredients, zest is low, HUOLUO YOU had no side effect and preparation method thereof, belongs to medicine oil production technical field.
Background technology
HUOLUO YOU be a kind of be made up of multiple quintessence oil class and Mentholum there is relaxing muscles and tendons and activating QI and blood in the collateral, there is the dissipating blood stasis that dispels the wind, the product of the effect of dispelling cold by warming the meridian, expelling wind and removing dampness, promoting blood circulation and stopping pain.Can be used for muscular soreness, rheumatic ostalgia, new and oldly to sprain, arthritis pain, mosquito are bitten, sprain swell and ache, trick is swollen and ache, waist hamstring pain, bony spur, sciatica, bones and muscles pain, pelvic bone twinge, traumatic injury old trouble, minor carbuncle swells and ache, skin pruritus, mosquito bite and insect bite, the dizzy wave of journey, dizzy belly pain, sphere of action is wide.
Have the category of various active effect on the market, its function is uneven, and effect is very many, and uses position wide.Use position is wide, and less pertinence is strong, and cause product in use can there is difference on effect, more severe patient may not play the effect that product is mentioned.And existing product zest is strong, makes with burning sensation, severe patient meeting calcination skin; Abnormal smells from the patient is pungent, flavour of a drug are strong, it is simple and crude to pack, and is not suitable for using in public places.Therefore develop a kind of that have no irritating odor, that there is effect difference of the most effectively administering specific part, avoiding existence when using different parts HUOLUO YOU tool to be of great significance.
Chinese patent, the patent No.: 200710090374.7; A pharmaceutical composition for HUOLUO YOU, is developed through pulverizing, heating by 21 kinds of Chinese crude drugs such as Borneolum Syntheticum, Mentholum, Radix Cynanchi Paniculati, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Rhizoma Curcumae, false Fructus Litchi, Caulis Spatholobi.Though there is effect of anti-inflammation detumescence, strong muscle dredging collateral, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, but product in use may exist difference on effect, therefore develop and a kind of the HUOLUO YOU tool that specific part is the most effectively administered to be of great significance.
The invention adopts pure natural plant ingredients, and zest is low, has no side effect; Not only effectively can improve the problems such as cervical vertebra muscle is tight, cervical vertebra stiffness, more can promote local blood flow, supplement brain oxygen, there is effect of refreshment, warm cotton is soft, permeate gradually, promote comfortable, oxygen refreshment of living, for people bring brand-new sensation; This product adopts ball-type design, and the small and exquisite exquisiteness of outward appearance is easy to use, is easy to carry.
Summary of the invention
The object of the invention is to utilize unique extracting technique of Chinese medicine effectively to retain the outer package of ingredient, novel formula theory and exquisiteness; thus accomplish specially to control special; specific part is the most effectively administered; avoid effect difference existed when using different parts, low stimulation better protects skin.The small and exquisite exquisiteness of outward appearance, fragrant odour are charming, easy to carry and use.
Strong in order to solve traditional HUOLUO YOU zest, outward appearance and packaging material simple and crude, be not easy to carry and use, the problems such as abnormal smells from the patient is pungent, the present invention by process innovation, a kind of innovation of exploitation HUOLUO YOU preparation technology, the technical scheme adopted is:
A kind of innovation HUOLUO YOU, be made up of the weight portion of following component: rice tunning filtrate 25-30 part, Folium Artemisiae Argyi extract 10-16 part, Flos Carthami extract 5-14 part, Radix Notoginseng extract 12-13 part, Herba speranskiae tuberculatae extract 10-11 part, Folium Ginkgo extract 8-9 part, oat germ oil 6-7 part, red sage root extract 6-7 part, Herba Menthae leaf oil 5-6 part, Angelica roots 4-5 part, turmeric oil 3-4 part.
Innovate a preparation method for HUOLUO YOU, comprise the steps:
(1) preparation of extract: raw material Folium Artemisiae Argyi, Flos Carthami, Radix Notoginseng, Herba speranskiae tuberculatae, Semen Ginkgo, Radix Salviae Miltiorrhizae, angelica root are cleaned up, at 50-60 DEG C, adopt liquid nitrogen cryogenics to pulverize after drying and dehydrating, in terrine, carry out low temperature seal with 45-55 degree jowar wine again and soak 10-20 days, adopt conventional backflow extractive technique to extract leachate, filter, concentrated after, detect outward appearance, microorganism qualified after, sealed storage at low temperatures, stand-by;
(2) preparation of rice tunning filtrate: by rice acetobacter and Lactobacillus plantarum fermentation, filtering fermentation liquor obtains rice tunning filtrate;
(3) clean up with the aquesterilisa of the 80-100 DEG C cylinder of production, container, valve be correlated with apparatus, then use the ethanol disinfection of 75%, for subsequent use;
(4) rice tunning filtrate 25-30 part is taken, Folium Artemisiae Argyi extract 10-16 part, Flos Carthami extract 5-14 part, Radix Notoginseng extract 12-13 part, Herba speranskiae tuberculatae extract 10-11 part, Folium Ginkgo extract 8-9 part, red sage root extract 6-7 part, Angelica roots 4-5 part, adds and produces in container, stir and obtain A group material; Take oat germ oil 6-7 part, Herba Menthae leaf oil 5-6 part, turmeric oil 3-4 part, adds in A group material, stirs, detect outward appearance and microorganism qualified after, pack.
Conventional backflow extraction conditions described in step (1) is: temperature 50-60 DEG C, solid-liquid ratio 1:10-1:50g/ml.
In low temperature seal immersion described in step (1), low temperature is 3 DEG C-8 DEG C.
The composite ratio of the acetobacter described in step (2) and Lactobacillus plantarum is 1:2, and addition is 3-5%; Fermentation condition is fermentation temperature 25-35 DEG C, pH5.5-6.5, fermentation time 24-36h.
The present invention relative to the beneficial effect of prior art is:
The invention adopts pure natural plant ingredients, zest is low, have no side effect, with away from dangerous, safety is unique for principle, aim at fatigue of driving, doze off, feel sleepy, dizziness, bradykinesia, lasting work, computer applications worker, cervical vertebra patient, go on business, travel, fieldworker etc. and the work of a conscience of giving birth to; Not only effectively can improve the problems such as cervical vertebra muscle is tight, cervical vertebra stiffness, more can promote local blood flow, supplement brain oxygen, there is effect of refreshment, warm cotton is soft, permeate gradually, promote comfortable, oxygen refreshment of living, for people bring brand-new sensation; This product adopts ball-type design, and the small and exquisite exquisiteness of outward appearance is easy to use, is easy to carry.
The experiment effect data of this product are as follows:
According to cherry, how youngster's latest data shows, after having 50%-60% user to smear 3-10 minute, becomes clear with expression in the eyes, the effect of visual cognitive ability; And natural plants more to impart energy liquid quality salubrious, non-greasy, effect of fragrant odour charming (have multiple natural plant fragrance available); Can emphasis be applied in cervical vertebra after both sides upper and lower 5-8 centimeters, temple place, left and right loop smear, on lip under nose between etc. position effect the most obvious, conscience quality, the sustainable 1-2 of drug effect hour (depending on individual physique and applying amount), uses after three days, symptom is had to effect of unrivalled improvement.
The invention and domestic multiple types carry out Experimental comparison like hit product, and experimental data is the average data of test number clinical testing data, and statistical data is as follows:
Detailed description of the invention
Be described in further details the present invention below by embodiment, these embodiments are only used for the present invention is described, do not limit the scope of the invention, the specific embodiment of the invention is implemented by Synthesis and applications two aspect.
Embodiment 1
A kind of innovation HUOLUO YOU, be made up of the weight portion of following component: rice tunning filtrate 25 parts, Folium Artemisiae Argyi extract 10 parts, Flos Carthami extract 5 parts, Radix Notoginseng extract 10 parts, Herba speranskiae tuberculatae extract 10 parts, Folium Ginkgo extract 8 parts, oat germ oil 6 parts, red sage root extract 6 parts, Herba Menthae leaf oil 5 parts, Angelica roots 4 parts, turmeric oil 3 parts.
Innovate a preparation method for HUOLUO YOU, comprise the steps:
(1) preparation of extract: raw material Folium Artemisiae Argyi, Flos Carthami, Radix Notoginseng, Herba speranskiae tuberculatae, Semen Ginkgo, Radix Salviae Miltiorrhizae, angelica root are cleaned up, at 50 DEG C, adopt liquid nitrogen cryogenics to pulverize after drying and dehydrating, in 3 DEG C of low temperature terrines, carry out low temperature seal with 45 degree of jowar wines again and soak 20 days, adopt conventional backflow extractive technique to leachate at temperature 60 C, carry out under solid-liquid ratio 1:50g/ml condition extracting, filter, concentrated after, detect outward appearance, microorganism qualified after, sealed storage at low temperatures, stand-by;
(2) preparation of rice tunning filtrate: by rice acetobacter and Lactobacillus plantarum (composite ratio is 1:2) fermentation, addition is 3%, and fermentation condition is fermentation temperature 35 DEG C, pH6.5, fermentation time 36h; Filtering fermentation liquor obtains rice tunning filtrate;
(3) clean up with the aquesterilisa of the 80 DEG C cylinder of production, container, valve be correlated with apparatus, then use the ethanol disinfection of 75%, for subsequent use;
(4) rice tunning filtrate 25 parts is taken, Folium Artemisiae Argyi extract 10 parts, Flos Carthami extract 5 parts, Radix Notoginseng extract 10 parts, Herba speranskiae tuberculatae extract 10 parts, Folium Ginkgo extract 8 parts, red sage root extract 6 parts, Angelica roots 4 parts, adds and produces in container, stir and obtain A group material; Take oat germ oil 6 parts, Herba Menthae leaf oil 5 parts, turmeric oil 3 parts, add in A group material, stir, detect outward appearance and microorganism qualified after, pack.
Embodiment 2
A kind of innovation HUOLUO YOU, be made up of the weight portion of following component: rice tunning filtrate 30 parts, Folium Artemisiae Argyi extract 16 parts, Flos Carthami extract 14 parts, Radix Notoginseng extract 13 parts, Herba speranskiae tuberculatae extract 11 parts, Folium Ginkgo extract 9 parts, oat germ oil 7 parts, red sage root extract 7 parts, Herba Menthae leaf oil 6 parts, Angelica roots 5 parts, turmeric oil 4 parts.
Innovate a preparation method for HUOLUO YOU, comprise the steps:
(1) preparation of extract: raw material Folium Artemisiae Argyi, Flos Carthami, Radix Notoginseng, Herba speranskiae tuberculatae, Semen Ginkgo, Radix Salviae Miltiorrhizae, angelica root are cleaned up, at 60 DEG C, adopt liquid nitrogen cryogenics to pulverize after drying and dehydrating, in 8 DEG C of low temperature terrines, carry out low temperature seal with 55 degree of jowar wines again and soak 10 days, adopt conventional backflow extractive technique to leachate at temperature 50 C, carry out under solid-liquid ratio 1:10g/ml condition extracting, filter, concentrated after, detect outward appearance, microorganism qualified after, sealed storage at low temperatures, stand-by;
(2) preparation of rice tunning filtrate: by rice acetobacter and Lactobacillus plantarum (composite ratio is 1:2) fermentation, addition is 5%, and fermentation condition is fermentation temperature 25 DEG C, pH5.5, fermentation time 24h; Filtering fermentation liquor obtains rice tunning filtrate;
(3) clean up with the aquesterilisa of the 100 DEG C cylinder of production, container, valve be correlated with apparatus, then use the ethanol disinfection of 75%, for subsequent use;
(4) rice tunning filtrate 30 parts is taken, Folium Artemisiae Argyi extract 16 parts, Flos Carthami extract 14 parts, Radix Notoginseng extract 13 parts, Herba speranskiae tuberculatae extract 11 parts, Folium Ginkgo extract 9 parts, red sage root extract 7 parts, Angelica roots 5 parts, adds and produces in container, stir and obtain A group material; Take oat germ oil 7 parts, Herba Menthae leaf oil 6 parts, turmeric oil 4 parts, add in A group material, stir, detect outward appearance and microorganism qualified after, pack.
Embodiment 3
A kind of innovation HUOLUO YOU, be made up of the weight portion of following component: rice tunning filtrate 28 parts, Folium Artemisiae Argyi extract 14 parts, Flos Carthami extract 10 parts, Radix Notoginseng extract 12.5 parts, Herba speranskiae tuberculatae extract 10.5 parts, Folium Ginkgo extract 8.5 parts, oat germ oil 6.5 parts, red sage root extract 6.5 parts, Herba Menthae leaf oil 5.5 parts, Angelica roots 4.5 parts, turmeric oil 3.5 parts.
Innovate a preparation method for HUOLUO YOU, comprise the steps:
(1) preparation of extract: raw material Folium Artemisiae Argyi, Flos Carthami, Radix Notoginseng, Herba speranskiae tuberculatae, Semen Ginkgo, Radix Salviae Miltiorrhizae, angelica root are cleaned up, at 55 DEG C, adopt liquid nitrogen cryogenics to pulverize after drying and dehydrating, in 5 DEG C of low temperature terrines, carry out low temperature seal with 50 degree of jowar wines again and soak 15 days, adopt conventional backflow extractive technique to leachate temperature 55 DEG C, carry out under solid-liquid ratio 1:25g/ml condition extracting, filter, concentrated after, detect outward appearance, microorganism qualified after, sealed storage at low temperatures, stand-by;
(2) preparation of rice tunning filtrate: by rice acetobacter and Lactobacillus plantarum (composite ratio is 1:2) fermentation, addition is 4%, and fermentation condition is fermentation temperature 30 DEG C, pH6.0, fermentation time 30h; Filtering fermentation liquor obtains rice tunning filtrate;
(3) clean up with the aquesterilisa of the 90 DEG C cylinder of production, container, valve be correlated with apparatus, then use the ethanol disinfection of 75%, for subsequent use;
(4) rice tunning filtrate 28 parts is taken, Folium Artemisiae Argyi extract 14 parts, Flos Carthami extract 10 parts, Radix Notoginseng extract 12.5 parts, Herba speranskiae tuberculatae extract 10.5 parts, Folium Ginkgo extract 8.5 parts, Angelica roots 4.5 parts, adds and produces in container, stir and obtain A group material; Take oat germ oil 6.5 parts, Herba Menthae leaf oil 5.5 parts, turmeric oil 3.5 parts, add in A group material, stir, detect outward appearance and microorganism qualified after, pack.
Embodiment 4
A kind of innovation HUOLUO YOU, be made up of the weight portion of following component: rice tunning filtrate 27 parts, Folium Artemisiae Argyi extract 16 parts, Flos Carthami extract 8 parts, Radix Notoginseng extract 12 parts, Herba speranskiae tuberculatae extract 10 parts, Folium Ginkgo extract 8 parts, oat germ oil 6 parts, red sage root extract 6 parts, Herba Menthae leaf oil 5 parts, Angelica roots 4 parts, turmeric oil 3 parts.
Innovate a preparation method for HUOLUO YOU, comprise the steps:
(1) preparation of extract: raw material Folium Artemisiae Argyi, Flos Carthami, Radix Notoginseng, Herba speranskiae tuberculatae, Semen Ginkgo, Radix Salviae Miltiorrhizae, angelica root are cleaned up, at 50 DEG C, adopt liquid nitrogen cryogenics to pulverize after drying and dehydrating, in 5 DEG C of low temperature terrines, carry out low temperature seal with 50 degree of jowar wines again and soak 10 days, adopt conventional backflow extractive technique to leachate temperature 55 DEG C, carry out under solid-liquid ratio 1:30g/ml condition extracting, filter, concentrated after, detect outward appearance, microorganism qualified after, sealed storage at low temperatures, stand-by;
(2) preparation of rice tunning filtrate: by rice acetobacter and Lactobacillus plantarum (composite ratio is 1:2) fermentation, addition is 5%, and fermentation condition is fermentation temperature 30 DEG C, pH6.5, fermentation time 28h; Filtering fermentation liquor obtains rice tunning filtrate;
(3) clean up with the aquesterilisa of the 100 DEG C cylinder of production, container, valve be correlated with apparatus, then use the ethanol disinfection of 75%, for subsequent use;
(4) rice tunning filtrate 27 parts is taken, Folium Artemisiae Argyi extract 16 parts, Flos Carthami extract 8 parts, Radix Notoginseng extract 12 parts, Herba speranskiae tuberculatae extract 10 parts, Folium Ginkgo extract 8 parts, Angelica roots 4 parts, adds and produces in container, stir and obtain A group material; Take oat germ oil 6 parts, Herba Menthae leaf oil 5 parts, turmeric oil 3 parts, add in A group material, stir, detect outward appearance and microorganism qualified after, pack.
Embodiment 5
A kind of innovation HUOLUO YOU, be made up of the weight portion of following component: rice tunning filtrate 26 parts, Folium Artemisiae Argyi extract 12 parts, Flos Carthami extract 5 parts, Radix Notoginseng extract 13 parts, Herba speranskiae tuberculatae extract 10 parts, Folium Ginkgo extract 8 parts, oat germ oil 6 parts, red sage root extract 6 parts, Herba Menthae leaf oil 5 parts, Angelica roots 4 parts, turmeric oil 4 parts.
Innovate a preparation method for HUOLUO YOU, comprise the steps:
(1) preparation of extract: raw material Folium Artemisiae Argyi, Flos Carthami, Radix Notoginseng, Herba speranskiae tuberculatae, Semen Ginkgo, Radix Salviae Miltiorrhizae, angelica root are cleaned up, at 50 DEG C, adopt liquid nitrogen cryogenics to pulverize after drying and dehydrating, in 8 DEG C of low temperature terrines, carry out low temperature seal with 50 degree of jowar wines again and soak 15 days, adopt conventional backflow extractive technique to leachate temperature 55 DEG C, carry out under solid-liquid ratio 1:20g/ml condition extracting, filter, concentrated after, detect outward appearance, microorganism qualified after, sealed storage at low temperatures, stand-by;
(2) preparation of rice tunning filtrate: by rice acetobacter and Lactobacillus plantarum (composite ratio is 1:2) fermentation, addition is 4%, and fermentation condition is fermentation temperature 30 DEG C, pH6.0, fermentation time 30h; Filtering fermentation liquor obtains rice tunning filtrate;
(3) clean up with the aquesterilisa of the 85 DEG C cylinder of production, container, valve be correlated with apparatus, then use the ethanol disinfection of 75%, for subsequent use;
(4) rice tunning filtrate 26 parts is taken, Folium Artemisiae Argyi extract 12 parts, Flos Carthami extract 5 parts, Radix Notoginseng extract 13 parts, Herba speranskiae tuberculatae extract 10 parts, Folium Ginkgo extract 8 parts, Angelica roots 4 parts, adds and produces in container, stir and obtain A group material; Take oat germ oil 6 parts, Herba Menthae leaf oil 5 parts, turmeric oil 4 parts, add in A group material, stir, detect outward appearance and microorganism qualified after, pack.

Claims (5)

1. a HUOLUO YOU, it is characterized in that: be made up of the weight portion of following component: rice tunning filtrate 25-30 part, Folium Artemisiae Argyi extract 10-16 part, Flos Carthami extract 5-14 part, Radix Notoginseng extract 12-13 part, Herba speranskiae tuberculatae extract 10-11 part, Folium Ginkgo extract 8-9 part, oat germ oil 6-7 part, red sage root extract 6-7 part, Herba Menthae leaf oil 5-6 part, Angelica roots 4-5 part, turmeric oil 3-4 part.
2. for the preparation of a method for HUOLUO YOU according to claim 1, it is characterized in that: comprise the steps:
(1) preparation of extract: raw material Folium Artemisiae Argyi, Flos Carthami, Radix Notoginseng, Herba speranskiae tuberculatae, Semen Ginkgo, Radix Salviae Miltiorrhizae, angelica root are cleaned up, at 50-60 DEG C, adopt liquid nitrogen cryogenics to pulverize after drying and dehydrating, in terrine, carry out low temperature seal with 45-55 degree jowar wine again and soak 10-20 days, adopt conventional backflow extractive technique to extract leachate, filter, concentrated after, detect outward appearance, microorganism qualified after, sealed storage at low temperatures, stand-by;
(2) preparation of rice tunning filtrate: by rice acetobacter and Lactobacillus plantarum fermentation, filtering fermentation liquor obtains rice tunning filtrate;
(3) clean up with the aquesterilisa of the 80-100 DEG C cylinder of production, container, valve be correlated with apparatus, then use the ethanol disinfection of 75%, for subsequent use;
(4) rice tunning filtrate 25-30 part is taken, Folium Artemisiae Argyi extract 10-16 part, Flos Carthami extract 5-14 part, Radix Notoginseng extract 12-13 part, Herba speranskiae tuberculatae extract 10-11 part, Folium Ginkgo extract 8-9 part, red sage root extract 6-7 part, Angelica roots 4-5 part, adds and produces in container, stir and obtain A group material; Take oat germ oil 6-7 part, Herba Menthae leaf oil 5-6 part, turmeric oil 3-4 part, adds in A group material, stirs, detect outward appearance and microorganism qualified after, pack.
3. the preparation method of a kind of HUOLUO YOU according to claim 2, is characterized in that: the conventional backflow extraction conditions described in step (1) is: temperature 50-60 DEG C, solid-liquid ratio 1:10-1:50g/ml.
4. the preparation method of a kind of HUOLUO YOU according to claim 2, is characterized in that: in the described low temperature seal immersion described in step (1), low temperature is 3 DEG C-8 DEG C.
5. the preparation method of a kind of HUOLUO YOU according to claim 2, is characterized in that: the composite ratio of the acetobacter described in step (2) and Lactobacillus plantarum is 1:2, and addition is 3-5%; Fermentation condition is fermentation temperature 25-35 DEG C, pH5.5-6.5, fermentation time 24-36h.
CN201510521914.7A 2015-08-24 2015-08-24 A kind of HUOLUO YOU and preparation method thereof Active CN105106834B (en)

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CN113069388A (en) * 2020-01-06 2021-07-06 广州樱奈儿化妆品有限公司 Massage cream for relieving cervical vertebra pain and preparation method thereof

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CN102078491A (en) * 2010-12-28 2011-06-01 韩召选 Fumigating and washing medicine decoction for eliminating blood stasis and activating blood circulation and use method thereof
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Publication number Priority date Publication date Assignee Title
CN113069388A (en) * 2020-01-06 2021-07-06 广州樱奈儿化妆品有限公司 Massage cream for relieving cervical vertebra pain and preparation method thereof

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