CN102614102A - Dandruff-removing medicinal composition and preparation method thereof - Google Patents
Dandruff-removing medicinal composition and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a dandruff-removing medicinal composition and a preparation method thereof, and provides a Dai medicament with an extremely good dandruff-removing effect and a Chinese medicine combined technology. The dandruff-removing medicinal composition comprises the following raw materials in percentage by weight: 120-160 percent of peruvian bark, 80-120 percent of whorlleaf stonecrop herb, 90-130 percent of root-bark of ditlany, 80-120 percent of Chinese arborvitae twig, 110-150 percent of lightyellow sophora root and 60-80 percent of giant knotweed. The preparation method comprises the following steps of: extracting a Chinese arborvitae twig percolate with ethanol; extracting an emulsified concentrated solution of the percolate at a low temperature; preparing a decoction of other components; filtering the decoction and combining; and adding purified water or concentrating till the total amount is 10 kilograms to obtain the dandruff-removing medicinal composition. The dandruff-removing medicinal composition is taken as an adding component of a washing substance for washing hair, has a remarkable dandruff-removing effect, is free from toxic and side effects, is made of readily-available raw materials, and is suitable for popularizing and applying. According to the technical scheme of the invention, the dandruff-removing medicinal composition is a traditional Chinese medicine, and a new path is researched for the development of Dai medicaments.
Description
Technical field
The present invention relates to a kind of be used for the being added on a kind of antidandruff agent compositions of hair washing articles for washing and the method for preparing of said composition.Be specifically related to a kind of antidandruff agent compositions and preparation method thereof.
Background technology
The incomplete statistics of World Health Organization (WHO); The dandruff sickness rate is more than 65%, and China's interrelated data investigation shows that the teenager sickness rate is more than 70%; The male is 100% dandruff of suffering from various degree almost in life, and wherein having more than 5% due to illness, feelings have had a strong impact on normal work and life.The main flow of existing shampoo product is a chemicals, and industrial chemicals produces certain stimulation to human body head skin, has increased the weight of the generation of scalp itch and dandruff from another point of view.The dandruff medicine for external use is the quasi drugs faster of market development in recent years; Dandruff medicine for external use total sales volume in 2010 is about 185 hundred million according to statistics; Continued to be growing trend over the past two years, increasing degree is more than 30%, and there is the eager market demand in vast consumer to removing the dandruff product.
Chinese patent CN200810030458.6 " a kind of black hair, hair growth promoting nutritional solution and preparation method thereof " discloses a kind of black hair, hair growth promoting nutritional solution and method for preparing; Flos Carthami, Radix Rhodiolae, Radix Angelicae Sinensis, Ramulus Mori, Galla Chinensis, brave ear nine dead Herba Hylothelephii Verticillatis are dried the back pulverize, infusion is more than 5 months in the adding pure grain wine; After Salix babylonica L., Rhizoma Zingiberis Recens, Bulbus Allii, Cacumen Platycladi leaf removed surface moisture, add in the pure grain wine infusion more than 2 months; The wine mixing of above two kinds of infusions is blent and can be used.Product of the present invention is coated with outward can stimulate the hair leather bag, significantly improves its physiological function, has the effect of black hair, hair growth promoting, simultaneously to anti-dandruff and improve hair quality good effect is also arranged.
It is antidandruff and antipruritic shampoo of processing of raw material and preparation method thereof with Chinese medicines such as Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae), Fructus Xanthii, Cacumen Platycladi leaves that Chinese patent CN200910114311.X " Chinese medicine antidandruff and antipruritic shampoo and preparation method thereof " discloses a kind of; The various herbal medicine immersions that compatibility is good are in the fermented wine and the mixed liquor that makes vinegar; The certain hour after-filtration extracts immersion liquid, immersion liquid is mixed with surfactant, auxiliary agent and water again, can obtain shampoo of the present invention behind the homogenizing; Because Chinese medicine ingredients not only has the sterilizing and itch-relieving effect; And effective ingredient can be penetrated into the deep layer root of hair, effectively moistens scalp, thereby reduced the generation of the dandruff.
Chinese patent CN01106997.X " anti-avulsion, hair growth promoting, black hair, hair care, dandruff-controlling shampoo " has introduced a kind of anti-avulsion, hair growth promoting, black hair, hair care, dandruff-controlling shampoo, it is characterized in that it by the following letter rank mallet Mulberry of pouring, and Fructus Gleditsia 40-60 restrains; Radix Polygoni Multiflori 20-45 gram; Radix Angelicae Sinensis 20-45 gram; Radix Rehmanniae 15-35 gram; Radix Rehmanniae Preparata 15-35 gram; Semen sojae atricolor 40-65 gram; Fructus Cnidii 10-25 gram; Radix Astragali 10-25 gram; Radix Aucklandiae 10-25 gram; Olibanum 10-25 gram; Myrrha 10-25 gram; Rhizoma Chuanxiong 10-30 gram; Poria 5-15 gram; Radix Glycyrrhizae 3-10 gram, said medicine decocted into extract after, removing slag gets final product.The present invention compares with other shampoo for the composition that pure natural plant extracts, and the property of medicine is stronger, and comprehensively, thoughtfully, result of use is remarkable, and is without any side effects.
Chinese patent CN200710159008.2 " antidandruff and antipruritic shampoo and method for making thereof " has introduced a kind of shampoo of removing scurf and relieving itching; Contain surfactant sodium lauryl sulphate or lauryl alcohol sulphuric acid ethanolamine salt; Along the full-bodied silicone oil of lubrication prescription HMW, wherein also contain Cacumen Platycladi leaf and ZHIMAGEN extracting solution.Prescription that the present invention is unique and effective composition can the percdation root of hairs; Replenish required nutrition in the hair, and can remove the residue and the dandruff of hair effectively, suppress the growth of the dandruff; The protection hair is not impaired, adheres to can the removing scurf and relieving itching effect remarkable for a long time.
Chinese patent CN200410088762.8
"A kind of natural hair tonic and trichomadesis proof hair lotion and preparation method thereof " a kind of natural hair tonic and trichomadesis proof hair lotion and preparation method thereof is disclosed, the quality proportioning of this natural hair tonic and trichomadesis proof hair lotion is: Folium Japanse Galangal powder (removing slag) 5%-6%, light flour 6%-8%; Oleum Sesami 0.4%-0.5%, Alpinia japonica (Thunb.) Miq. oil 0.1%-0.2%, IES 5%-8%; Sal 1%-2%, triumphant loose 0.1%-0.3%, essence 0.5%-1.5%; Cera Flava 8%-10%, medicated wine 65%-70%.Its concrete manufacture method is seen description.This natural hair tonic and trichomadesis proof hair lotion has efficiently anti-loss, quick hair growth promoting, treatment sore head, itching relieving effect.Can also make hair smooth, elegant, and have good anti-dandruff effect.
It mainly is to be main strong effect antibacterial type with the antibiotic that existing market has like product; So that bactericidal effect is celebrated fast and effectively; Be to solve the essential drugs that serious dandruff infects clinically, defective be they at anti-infective simultaneously, also make the patient produce drug dependence and Drug resistance.
Above document shows, the hair lotion of Chinese Medicine and Clavicular has had the research report, but new through looking into, and also do not appear in the newspapers with the lotion of Dai Nationality's medicine, Chinese Medicine and Clavicular.
Summary of the invention
The objective of the invention is to disclose a kind of antidandruff agent compositions, another object of the present invention provides the method for preparing of said composition, and the antidandruff agent compositions is to be prepared from Dai Nationality's medicine and Chinese medicine composition; Belong to pure Chinese herbal and crude drugs preparations, safe in utilization, raw material is easy to get; Manufacture method is simple; Be used for the interpolation composition of shampoo, the anti-dandruff effect of its sterilizing and itch-relieving is obvious, and is cheap.
Technical scheme is following:
The antidandruff agent compositions, mainly by following weight than feedstock production: ledger bark 120-160, nine dead Herba Hylothelephii Verticillati 80-120, favus skin 90-130; Cacumen Platycladi 80-120, Radix Sophorae Flavescentis 110-150, preferred each component weight is: ledger bark 130-150, nine dead Herba Hylothelephii Verticillati 90-110 Chinese medicines; Favus skin 100-120, Cacumen Platycladi 90-110, Radix Sophorae Flavescentis 120-140; More preferably each component weight is: ledger bark 135-145, nine dead Herba Hylothelephii Verticillati 95-105, favus skin 105-115; Cacumen Platycladi 95-105, Radix Sophorae Flavescentis 125-135 can have the weight ratio raw material: Rhizoma Polygoni Cuspidati 60-80.
The combination of anti-dandruff medicine is got by the following steps preparation:
One, extracts the Cacumen Platycladi percolate
Cacumen Platycladi 80-120 gram is put in the container, for the first time, adds 40%-60% ethanol, soaks 12-24 hour, puts and leaves standstill 12 hours in the percolator, collects percolate; For the second time, add 40%-60% ethanol, soaked 8-12 hour, put and leave standstill 6 hours in the percolator, collect percolate, it is subsequent use to merge above-mentioned secondary percolate meter 800-1200 milliliter;
Two, produce the emulsifying concentrated solution of percolate
One) condition: vacuum-0.4Mpa, 50 ± 5 ℃ of temperature concentrate, and reclaim ethanol, and it is subsequent use to collect concentrate;
Two) in concentrate, add tween 80, the 35-45 milliliter stirs, and it is subsequent use to make emulsifying concentrated solution;
Three, produce decoction liquor
With raw material ledger bark 120-160 gram, nine dead Herba Hylothelephii Verticillati 80-120 grams, favus skin 90-130 gram, Radix Sophorae Flavescentis 110-150 gram; After Rhizoma Polygoni Cuspidati 60-80 gram mixed, water decocted 2 times, boiled 2 hours for the first time; Boiled 1 hour for the second time, make decoction liquor after filtering respectively and boil liquid, merging, subsequent use;
Four, the emulsifying concentrated solution of step 2 and the decoction liquor of step 3 are merged, when total amount is less than 10 kilograms after merging, be supplemented to 10 kilograms with pure water; During more than 10 kilograms; At vacuum-0.4Mpa, under 50 ± 5 ℃ of conditions of temperature, be concentrated into 10 kilograms; Through sterilization processing, packing, be antidandruff agent compositions of the present invention.
In the technical scheme of the present invention; Dai Nationality's explosive component is ledger bark (Cinchona cortex) and nine dead Herba Hylothelephii Verticillatis (Selaginella tamariscina (Beauv.) Spring); Belong to Dai Nationality's medicinal herbs medicine, the people of the Dai nationality come to treat various skin pruritus with it for generations, and effect all has public praise.Chinese medicinal ingredients is a favus skin, Cacumen Platycladi, Radix Sophorae Flavescentis, Rhizoma Polygoni Cuspidati.
Quinine is used its bark, and nine dead Herba Hylothelephii Verticillatis are used its herb.All count dosage with the weight after drying.Favus skin, Cacumen Platycladi, Radix Sophorae Flavescentis, Rhizoma Polygoni Cuspidati are used its prepared slices of Chinese crude drugs.
Drug effect is following:
(1) quinine: contain more than 30 kind of alkaloid.Modern a large amount of pharmacological evaluation shows; The comprehensive extract of the bark of quinine has strong antifungic action, researcher adopts the solid agar method, is blank determination extract antifungal activity with the salicylic acid, finds its 10 kinds of dermatophytosises to being tried; 5 kinds of deep fungals; 3 primary yeast appearance bacterium all have inhibition and killing action, obviously are better than control drug, are mainly used in antibacterial.
(2) nine dead Herba Hylothelephii Verticillatis: contain Vasobral, have the nourishing scalp, promote hair restoration.
(3) favus skin: have refrigerant, antiinflammatory, pain relieving and itching-relieving action, simultaneously various bacteria and fungus are had stronger inhibitory action.
(4) Cacumen Platycladi: contain fragrant volatile oil, have the detoxifcation of relieving inflammation or internal heat, the effect of reducing swelling and alleviating pain, sterilizing and itch-relieving.
(5) Radix Sophorae Flavescentis: have heat clearing away, dampness, parasite killing, diuresis.
(6) Rhizoma Polygoni Cuspidati: the function of Rhizoma Polygoni Cuspidati is heat-clearing and toxic substances removing, promoting blood circulation to restore menstrual flow.
More than in each composition, quinine, favus skin, Radix Sophorae Flavescentis, Cacumen Platycladi mainly are anti-inflammation and killing parasites for relieving itching effect; Rhizoma Polygoni Cuspidati, nine dead Herba Hylothelephii Verticillatis, mainly play promoting blood circulation to restore menstrual flow, nourish the scalp effect.In the prescription of the present invention, Dai Nationality's medicine and Chinese medicine unite two into one, and collaborative playing a role makes whole compositions anti-inflammation and sterilization itching-relieving action multiplication.
Low-temperature extraction is an innovation of the present invention.Active ingredient in the Cacumen Platycladi is a kind of volatile oil, under lower temperature, extracts, and can extract and retain down medicative composition wherein to greatest extent.If select conventional extracting process for use, the efficacy component volatilization is lost through experiment showed,, causes drug effect to reduce.
Technical scheme of the present invention provides a kind of result of use remarkable, no drug dependence, the dandruff-controlling shampoo that toxic and side effects is minimum.Compositions of the present invention has certain anti-avulsion, hair growth promoting, hair care effect.Compositions composition raw material sources of the present invention are abundant, inexpensive, and preparation technology is simple, and is easy to use, for numerous poor patients have brought hope, indicating well medical prevention prospect.
Antidandruff agent compositions of the present invention is main with Dai Nationality's medicine, cooperates Chinese medicine, the drug effect that new combination results is new.Through clinical verification, have the sterilizing and itch-relieving effect, treatment and prevention dandruff sick aspect, evident in efficacy, have the effect of generating and nourishing hair simultaneously.
The present invention has carried out the bacteriostasis property test and the skin irritation test of system, effect such as aforementioned.
The specific embodiment
Combine embodiment that the present invention is described further at present, but be not limited to embodiment.
Embodiment 1,
Get the raw materials ready to prepare 10 kilograms of antidandruff agent compositions of the present invention, weight is in gram:
Ledger bark 120, nine dead Herba Hylothelephii Verticillatis 110, favus skin 90, Cacumen Platycladi 120, Radix Sophorae Flavescentis 140,
Method for preparing:
One, extracts the Cacumen Platycladi percolate
Cacumen Platycladi is put in the container, for the first time, adds 50% ethanol, soaks 12-24 hour, puts and leaves standstill 12 hours in the percolator, collects percolate; For the second time, add 50% ethanol, soaked 8-12 hour, put and leave standstill 6 hours in the percolator, collect percolate, it is subsequent use to merge 800 milliliters of above-mentioned secondary percolate meters;
Two, produce the emulsifying concentrated solution of percolate
One) condition: vacuum-0.4Mpa, 50 ± 5 ℃ of temperature concentrate, and reclaim ethanol, and it is subsequent use to collect concentrate;
Two) in concentrate, add tween 80,35 milliliters, stir, it is subsequent use to make emulsifying concentrated solution;
Three, produce decoction liquor
After raw material ledger bark, nine dead Herba Hylothelephii Verticillatis, favus skin, Radix Sophorae Flavescentis, Rhizoma Polygoni Cuspidati mixing, water decocts 2 times, boils 2 hours for the first time, boils 1 hour for the second time, and filtration makes decoction liquor after boiling liquid, merging respectively, and is subsequent use;
Four, the emulsifying concentrated solution of step 2 and the decoction liquor of step 3 are merged, when total amount is less than 10 kilograms after merging, be supplemented to 10 kilograms with pure water; During more than 10 kilograms; At vacuum-0.4Mpa, under 50 ± 5 ℃ of conditions of temperature, be concentrated into 10 kilograms; Through sterilization processing, packing, be antidandruff agent compositions of the present invention.
Embodiment 2,
Get the raw materials ready to prepare 10 kilograms of antidandruff agent compositions of the present invention, weight is in gram:
Ledger bark 150, nine dead Herba Hylothelephii Verticillatis 95, favus skin 120, Cacumen Platycladi 90, Radix Sophorae Flavescentis 120,
Method for preparing:
One, extracts the Cacumen Platycladi percolate
Cacumen Platycladi is put in the container, for the first time, adds 45% ethanol, soaks 12-24 hour, puts and leaves standstill 12 hours in the percolator, collects percolate; For the second time, add 45% ethanol, soaked 8-12 hour, put and leave standstill 6 hours in the percolator, collect percolate, it is subsequent use to merge 1100 milliliters of above-mentioned secondary percolate meters;
Two, produce the emulsifying concentrated solution of percolate
One) condition: vacuum-0.4Mpa, 50 ± 5 ℃ of temperature concentrate, and reclaim ethanol, and it is subsequent use to collect concentrate;
Two) in concentrate, add tween 80,45 milliliters, stir, it is subsequent use to make emulsifying concentrated solution;
Three, produce decoction liquor
After raw material ledger bark, nine dead Herba Hylothelephii Verticillatis, favus skin, Radix Sophorae Flavescentis, Rhizoma Polygoni Cuspidati mixing, water decocts 2 times, boils 2 hours for the first time, boils 1 hour for the second time, and filtration makes decoction liquor after boiling liquid, merging respectively, and is subsequent use;
Four, the emulsifying concentrated solution of step 2 and the decoction liquor of step 3 are merged, when total amount is less than 10 kilograms after merging, be supplemented to 10 kilograms with pure water; During more than 10 kilograms; At vacuum-0.4Mpa, under 50 ± 5 ℃ of conditions of temperature, be concentrated into 10 kilograms; Through sterilization processing, packing, be antidandruff agent compositions of the present invention.
Embodiment 3,
Get the raw materials ready to prepare 10 kilograms of antidandruff agent compositions of the present invention, weight is in gram:
Ledger bark 140, nine dead Herba Hylothelephii Verticillatis 85, favus skin 130, Cacumen Platycladi 110, Radix Sophorae Flavescentis 130,
Method for preparing:
One, extracts the Cacumen Platycladi percolate
Cacumen Platycladi is put in the container, for the first time, adds 55%-60% ethanol, soaks 12-24 hour, puts and leaves standstill 12 hours in the percolator, collects percolate; For the second time, add 40%-60% ethanol, soaked 8-12 hour, put and leave standstill 6 hours in the percolator, collect percolate, it is subsequent use to merge 1000 milliliters of above-mentioned secondary percolate meters;
Two, produce the emulsifying concentrated solution of percolate
One) condition: vacuum-0.4Mpa, 50 ± 5 ℃ of temperature concentrate, and reclaim ethanol, and it is subsequent use to collect concentrate;
Two) in concentrate, add tween 80,40 milliliters, stir, it is subsequent use to make emulsifying concentrated solution;
Three, produce decoction liquor
After raw material ledger bark, nine dead Herba Hylothelephii Verticillatis, favus skin, Radix Sophorae Flavescentis, Rhizoma Polygoni Cuspidati mixing, water decocts 2 times, boils 2 hours for the first time, boils 1 hour for the second time, and filtration makes decoction liquor after boiling liquid, merging respectively, and is subsequent use;
Four, the emulsifying concentrated solution of step 2 and the decoction liquor of step 3 are merged, when total amount is less than 10 kilograms after merging, be supplemented to 10 kilograms with pure water; During more than 10 kilograms; At vacuum-0.4Mpa, under 50 ± 5 ℃ of conditions of temperature, be concentrated into 10 kilograms; Through sterilization processing, packing, be antidandruff agent compositions of the present invention.
Embodiment 4,
Get the raw materials ready to prepare 10 kilograms of antidandruff agent compositions of the present invention, weight is in gram:
Ledger bark 135, nine dead Herba Hylothelephii Verticillatis 100, favus skin 100, Cacumen Platycladi 100, Radix Sophorae Flavescentis 130,
Method for preparing:
One, extracts the Cacumen Platycladi percolate
Cacumen Platycladi is put in the container, for the first time, adds 40%-60% ethanol, soaks 12-24 hour, puts and leaves standstill 12 hours in the percolator, collects percolate; For the second time, add 40%-60% ethanol, soaked 8-12 hour, put and leave standstill 6 hours in the percolator, collect percolate, it is subsequent use to merge 950 milliliters of above-mentioned secondary percolate meters;
Embodiment 4 step 2, three identical with embodiment 3.
Embodiment 5,
Get the raw materials ready to prepare 10 kilograms of antidandruff agent compositions of the present invention, weight is in gram:
Ledger bark 120, nine dead Herba Hylothelephii Verticillatis 80, favus skin 90, Cacumen Platycladi 80, Radix Sophorae Flavescentis 110,
Method for preparing:
One, extracts the Cacumen Platycladi percolate
Cacumen Platycladi is put in the container, for the first time, adds 40%-60% ethanol, soaks 12-24 hour, puts and leaves standstill 12 hours in the percolator, collects percolate; For the second time, add 40%-60% ethanol, soaked 8-12 hour, put and leave standstill 6 hours in the percolator, collect percolate, it is subsequent use to merge 800 milliliters of above-mentioned secondary percolate meters;
Embodiment 5 step 2, three identical with embodiment 3.
Embodiment 6,
Prepare anti-dandruff lotion of medication
Any one compositions of the present invention among the embodiment 1-5, with volume ratio, anti-dandruff medicine group of the present invention is closed thing ︰ hair washing composition=2 ︰ 1, and the hair washing composition is a routine techniques, adopts conventional adding method to make anti-dandruff medicine washing liquid.
In compositions of the present invention, add hair washing composition AES Sodium Alcohol Ether Sulphate, AES-A ethoxylated alkyl ammonium sulfate, 6501 diethanolamine of fat acyl; Adding thermally homogenising stirs; Evenly the back adds the emulsifying of BS-12 fatty alkyl dimethyl betaine; Add sodium chloride, triumphant pine, essence at last, mixing.Cooling back fill,
Packing promptly gets, and is anti-dandruff lotion of medication.
The embodiment effect test:
Test with the acute eye irritation of the anti-dandruff medicine washing liquid of anti-dandruff preparation of pharmaceutical compositions of the present invention:
One, test material and method
1. tried thing: anti-dandruff medicine washing liquid, sample are liquid.
2. animal subject: 3 of the big ear rabbits of Japan are provided by Bio-medicinal Plant of Yunnan Prov..The animal quality certification number: word 2002066 is moved in Yunnan, regular grade, and production facility card number: word 2002067 is moved in Yunnan.Feedstuff is provided by this factory, the quality certification number: word 2002070 is moved in Yunnan.
3. test method: adopt " cosmetics health standard " acute eye irritation test method once will be tried thing 0.1ML and splash in the animal subject one branch hole conjunctival sac; Another branch hole is not managed down and is made own control; Closed 1 second; Splash into and tried behind the thing 30 seconds, when each is observed time point and keeps the score, observe with handheld slit lamp with the distillation washing.
Two, result of the test
Anti-dandruff medicine washing liquid is to White Rabbit eye irritation test results test condition: flushing in 30 seconds splashes into and is tried 1h behind the thing, 24h observes, and congested, edema appear in animal subject eye conjunctiva, observe behind the 48h, do not see toxic action.
Three, conclusion
Under this experimental condition, acute eye irritation test is judged to be microstimulation property by eye irritation reaction grade scale to the animal subject White Rabbit to be tried thing anti-dandruff medicine washing liquid.
Anti-dandruff medicine washing liquid skin irritation test with anti-dandruff preparation of pharmaceutical compositions of the present invention:
One, test material and method
1. tried thing: anti-dandruff medicine washing liquid, sample are liquid.
2. animal subject: 3 of the big ear rabbits of Japan are provided by Bio-medicinal Plant of Yunnan Prov..The animal quality certification number: word 2002066 is moved in Yunnan, regular grade, and production facility card number: word 2002067 is moved in Yunnan.Feedstuff is provided by this factory, the quality certification number: word 2002070 is moved in Yunnan.
3. test method: adopt " cosmetics health standard " skin irritation test method, 24H before the test cuts experimental animal back spinal column diamond wool each about 6cm of QUMAO scope
2Get and tried thing 0.5mL and directly spread upon on the side skin, cover, use the nonirritant immobilization with adhesive tape with clean gauze.The negative contrast of an other side.Take down gauze behind the 24H and remove the residual thing that tried, observe and smear the position dermoreaction and note down in removing 1h after being tried thing, 24h with warm water.
Two, result of the test
Anti-dandruff medicine washing liquid is to White Rabbit skin irritation test results test condition: flushing in 30 seconds
At viewing duration, experimental animal is tried thing position not show speckle, edema and other toxic action.
Three, conclusion
Under this experimental condition, tried thing anti-dandruff medicine washing liquid animal subject White Rabbit skin irritation is tested, be judged to be nonirritant according to the skin irritation strength grading.
Claims (6)
1. the antidandruff agent compositions is characterized in that, mainly by following weight than feedstock production:
Ledger bark 120-160, nine dead Herba Hylothelephii Verticillati 80-120, favus skin 90-130, Cacumen Platycladi 80-120, Radix Sophorae Flavescentis 110-150.
2. antidandruff agent compositions according to claim 1 is characterized in that, each component weight is:
Ledger bark 130-150, nine dead Herba Hylothelephii Verticillati 90-110 Chinese medicines, favus skin 100-120, Cacumen Platycladi 90-110, Radix Sophorae Flavescentis 120-140.
3. antidandruff agent compositions according to claim 2 is characterized in that, each component weight is:
Ledger bark 135-145, nine dead Herba Hylothelephii Verticillati 95-105, favus skin 105-115, Cacumen Platycladi 95-105, Radix Sophorae Flavescentis 125-135.
4. according to claim 1,2 or 3 described antidandruff agent compositions, it is characterized in that the weight ratio raw material is arranged: Rhizoma Polygoni Cuspidati 60-80.
5. antidandruff agent compositions method for preparing is characterized in that, is got by the following steps preparation:
One, extracts the Cacumen Platycladi percolate
Cacumen Platycladi 80-120 gram is put in the container, for the first time, adds 40%-60% ethanol, soaks 12-24 hour, puts and leaves standstill 12 hours in the percolator, collects percolate; For the second time, add 40%-60% ethanol, soaked 8-12 hour, put and leave standstill 6 hours in the percolator, collect percolate, it is subsequent use to merge above-mentioned secondary percolate meter 800-1200 milliliter;
Two, produce the emulsifying concentrated solution of percolate
One) condition: vacuum-0.4Mpa, 50 ± 5 ℃ of temperature concentrate, and reclaim ethanol, and it is subsequent use to collect concentrate;
Two) in concentrate, add tween 80, the 35-45 milliliter stirs, and it is subsequent use to make emulsifying concentrated solution;
Three, produce decoction liquor,
With raw material ledger bark 120-160 gram, nine dead Herba Hylothelephii Verticillati 80-120 grams, favus skin 90-130 gram, Radix Sophorae Flavescentis 110-150 gram, after the mixing, water decocts 2 times, boils 2 hours for the first time, boils 1 hour for the second time, makes decoction liquor after filtering respectively and boil liquid, merging, and is subsequent use;
Four, the decoction liquor with the emulsifying concentrated solution of step 2 and step 3 merges, and exceeds for 10 kilograms with total amount, and pure water is supplemented to 10 kilograms or at vacuum-0.4Mpa; Under 50 ± 5 ℃ of conditions of temperature; Be concentrated into 10 kilograms,, be antidandruff agent compositions of the present invention through sterilization processing, packing.
6. antidandruff agent compositions method for preparing according to claim 5 is characterized in that, in the step 3, adds raw material Rhizoma Polygoni Cuspidati 60-80 gram.
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| CN104208534A (en) * | 2014-09-22 | 2014-12-17 | 龚川瑞 | Anti-scurf pharmaceutical composition and preparation method thereof |
| CN104398661A (en) * | 2014-08-29 | 2015-03-11 | 钟书明 | Traditional Chinese medicine for removing dandruff and relieving scalp itch |
| CN105853314A (en) * | 2016-06-14 | 2016-08-17 | 马殿伟 | Anti-dandruff traditional Chinese medicine composition containing waltheria indica leaves and used for cosmetics |
| CN106421606A (en) * | 2016-10-28 | 2017-02-22 | 秦科 | Traditional Chinese medicine composition capable of removing dandruff and preparation method of traditional Chinese medicine composition |
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| CN108135830A (en) * | 2016-07-05 | 2018-06-08 | 尹好永 | Produce the method for preventing trichomadesis and trichogenous composition |
| CN108272671A (en) * | 2018-03-13 | 2018-07-13 | 名臣健康用品股份有限公司 | Have effects that the Chinese medicine composition of hair-loss preventing and hair-restoring and its application |
| CN109893486A (en) * | 2019-04-18 | 2019-06-18 | 无锡永如生物美容品有限公司 | A kind of plant enzyme shampoo |
| CN110897971A (en) * | 2019-12-27 | 2020-03-24 | 昆明远方生物制品有限公司 | Hair care cleaning composition containing selaginella tamariscina and preparation method thereof |
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| CN111658580A (en) * | 2020-06-23 | 2020-09-15 | 广西和桂集团有限公司 | Hair growth and/or hair blackening essence containing various peptides and plant extracts and preparation method thereof |
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| CN104398661A (en) * | 2014-08-29 | 2015-03-11 | 钟书明 | Traditional Chinese medicine for removing dandruff and relieving scalp itch |
| CN104208534A (en) * | 2014-09-22 | 2014-12-17 | 龚川瑞 | Anti-scurf pharmaceutical composition and preparation method thereof |
| CN105853314A (en) * | 2016-06-14 | 2016-08-17 | 马殿伟 | Anti-dandruff traditional Chinese medicine composition containing waltheria indica leaves and used for cosmetics |
| CN108135830A (en) * | 2016-07-05 | 2018-06-08 | 尹好永 | Produce the method for preventing trichomadesis and trichogenous composition |
| CN106421606A (en) * | 2016-10-28 | 2017-02-22 | 秦科 | Traditional Chinese medicine composition capable of removing dandruff and preparation method of traditional Chinese medicine composition |
| CN106726976A (en) * | 2016-12-28 | 2017-05-31 | 刘志勇 | A kind of anti-dandruff block fermentation medicine and its preparation method and application |
| CN108272671A (en) * | 2018-03-13 | 2018-07-13 | 名臣健康用品股份有限公司 | Have effects that the Chinese medicine composition of hair-loss preventing and hair-restoring and its application |
| CN110934783A (en) * | 2018-09-21 | 2020-03-31 | 珠海伊斯佳科技股份有限公司 | Dandruff-removing and itching-relieving composition containing Chinese herbal medicines, silicone oil-free amino acid shampoo containing composition, and preparation method and application of silicone oil-free amino acid shampoo |
| CN110934783B (en) * | 2018-09-21 | 2022-06-28 | 珠海伊斯佳科技股份有限公司 | Dandruff-removing and itching-relieving composition containing Chinese herbal medicines, silicone oil-free amino acid shampoo containing composition, and preparation method and application of silicone oil-free amino acid shampoo |
| CN109893486A (en) * | 2019-04-18 | 2019-06-18 | 无锡永如生物美容品有限公司 | A kind of plant enzyme shampoo |
| CN110897971A (en) * | 2019-12-27 | 2020-03-24 | 昆明远方生物制品有限公司 | Hair care cleaning composition containing selaginella tamariscina and preparation method thereof |
| CN111658580A (en) * | 2020-06-23 | 2020-09-15 | 广西和桂集团有限公司 | Hair growth and/or hair blackening essence containing various peptides and plant extracts and preparation method thereof |
| CN112138071A (en) * | 2020-10-11 | 2020-12-29 | 广州莱约生物科技有限公司 | Sterilizing and inflammation-diminishing composition and preparation method and application thereof |
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Denomination of invention: A dandruff removing drug composition and its preparation method Effective date of registration: 20230421 Granted publication date: 20130508 Pledgee: Agricultural Bank of China Limited by Share Ltd. Fumin County branch Pledgor: KUNMING YUANFANG BIOLOGICAL PRODUCTS CO.,LTD. Registration number: Y2023530000025 |