CN105853314A - Anti-dandruff traditional Chinese medicine composition containing waltheria indica leaves and used for cosmetics - Google Patents
Anti-dandruff traditional Chinese medicine composition containing waltheria indica leaves and used for cosmetics Download PDFInfo
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- CN105853314A CN105853314A CN201610414522.5A CN201610414522A CN105853314A CN 105853314 A CN105853314 A CN 105853314A CN 201610414522 A CN201610414522 A CN 201610414522A CN 105853314 A CN105853314 A CN 105853314A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
Abstract
The invention discloses an anti-dandruff traditional Chinese medicine composition containing waltheria indica leaves and used for cosmetics. The composition is prepared from, by weight, 8-16 parts of radix trichosanthes, 15-25 parts of waltheria indica leaves, 6-12 parts of cortex dictamni, 4-9 parts of blue gum, 0.2-0.5 part of agastache rugosus and 3-7 parts of quassia wood. By optimizing compatibility of the raw materials, the raw materials generate a synergistic interaction function and enhance the anti-dandruff effect of the composition, and the composition is mild in medicine effect, prepared through combining pure natural plant extracts, and small in side effect, wide in adaptability and low in cost.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf.
Background technology
Under normal circumstances, the epidermal cell at scalp, owing to the cell of those basalises is ceaselessly bred, and release to surface,
These cell maturations last, become and do not have lived cuticula to come off.When scalp is the most healthy, the cell come off be we not
The powder easily discovered, the most just can't see dandruff.But when scalp goes wrong, epidermal area cannot be ripe, then well
Peel off large stretch ofly, here it is dandruff.
Dandruff Producing reason mainly has two aspects: one is that microorganism (such as the fungies such as chlosma and bacterium) infection causes
Dermal cell division is accelerated;Two is that sebum secretion is the most vigorous, and sebum is attached on scalp together with the cell come off, the most just
Become dandruff in small, broken bits.So, anti-dandruff the best way is exactly growth and the suppression sebum secretion suppressing microorganism.
The Effect raw material that at present dandruff control shampoo containing of commercial type is added mainly include salicylic acid, pyrithione zinc, ketoconazole,
One or more in Climbazole and pyridone monoethanolamine, these anti-dandruff agent mainly reach anti-dandruff purpose by suppression microorganism.
These anti-dandruff agent are the material of chemical synthesis, and relatively big to the excitant of human body, the dandruff control shampoo containing containing above-mentioned raw materials has
Also scalp is caused while anti-dandruff effect certain injury.Along with scientific and technological development, growth in the living standard and hair quality is good for
The raising of Kang Yishi, people are more and more higher to the attention rate of shampoo, and Chinese medicine natural, green, safe and effective is anti-dandruff to be washed
Flood and particularly receive publicity.Dandruff control shampoo containing traditional Chinese medicines is little with its toxic and side effect, and the occupancy volume of the market share expands year by year, but logical
It is commonly present the problems such as curative effect is rapid not, active ingredient is inconspicuous.
Summary of the invention
It is an object of the invention to overcome the anti-dandruff weak effect in the presence of existing anti-dandruff Chinese medicine composition technology, anti-dandruff take effect slow
Not enough, it is provided that a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf.Said composition is joined by optimizing raw material
5, make to produce between raw medicinal material synergistic function, add the anti-dandruff effect of composition and the speed that takes effect, drug effect is gentle;
Said composition is combined by pure natural plant extract, and side effect is little, and wide adaptability is with low cost.
In order to realize foregoing invention purpose, the invention provides a kind of anti-dandruff Chinese traditional medicine composition for cosmetics containing snake woman's leaf
Thing, said composition is to be prepared from by the raw material of following weight: radices trichosanthis 8-16 part, snake woman's leaf 15-25 part,
Shaggy-fruited dittany 6-12 part, blue gum 4-9 part, wrinkled giant hyssop 0.2-0.5 part, quassia 3-7 part.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, wherein said radices trichosanthis, nature and flavor are sweet,
Micro-hardship, is slightly cold;Attach to the lung and stomach meridians, there is clearing heat-fire, promote the production of body fluid to quench thirst, effect of detumescence and apocenosis.It is mainly used in treating pyreticosis
Polydipsia, lung-heat type cough, interior heat quenches one's thirst, sore swollen toxin.
Wherein said snake woman's leaf, taste is pungent;Micro-sweet;Cold nature;The thoughts of returning home, kidney, lung channel;There is expelling wind and removing dampness;Heat-clearing solution
Effect of poison;It is mainly used in treating rheumatism bi Zheng;Abscess of throat;Under humid tropics;Carbuncle swells scrofula.
Wherein said shaggy-fruited dittany, nature and flavor are bitter;Salty;Cold;Return spleen, lung, small intestine, stomach, bladder warp;Have and dispel the wind, eliminating dampness,
Heat-clearing, effect of removing toxic substances;It is mainly used in treating sore wind-heat sore, mange, itchy skin eruption, arthralgia due to wind-dampness, jaundice.
Wherein said blue gum, bitter, cold in nature;Return liver, stomach warp;There is stomach invigorating, neuralgia, the merit controlling rheumatism, sprain
Effect, is mainly used in treating the infection of the upper respiratory tract, sphagitis, bronchitis, pneumonia, urgent, chronic nephropyeltis, enteritis, dysentery.
Wherein said wrinkled giant hyssop, nature and flavor are pungent, tepor.Return spleen, stomach, lung channel;Have and eliminate dampness with aromatics, and middle preventing or arresting vomiting, deliver solution
Effect of heat;Being mainly used in treating turbi damp obstructing in middle-JIAO, gastral cavity ruffian is vomitted, and summer-heat and damp table is demonstrate,proved, and damp-warm syndrome, from the beginning of, burnout of generating heat, uncomfortable in chest is not relaxed,
Cold-dampness closes heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Wherein said quassia, cold in nature, bitter;Return lung, large intestine channel;Have clearing heat and detoxicating;Effect of removing dampness and destroying parasites;Mainly
For treating anemopyretic cold, abscess of throat, diarrhea of suffering from diarrhoea, eczema, sore furuncle, venomous snake bite.For anemopyretic cold, throat swells
Bitterly, diarrhea of suffering from diarrhoea, eczema, sore furuncle, venomous snake bite.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, it is preferred that said composition is by following heavy
The raw material of amount part proportioning is prepared from: radices trichosanthis 10-14 part, snake woman's leaf 18-22 part, shaggy-fruited dittany 8-10 part, blue gum 5-8
Part, wrinkled giant hyssop 0.2-0.4 part, quassia 4-6 part;It is further preferred that said composition is to be prepared by the raw material of following weight
: radices trichosanthis 12 parts, 20 parts of snake woman's leaf, shaggy-fruited dittany 9 parts, blue gum 7 parts, wrinkled giant hyssop 0.3 part, quassia 5 parts.Logical
Crossing that above-mentioned preferably the synergistic function that can make composition is maximum, and anti-dandruff effect reaches optimal, side effect is minimum.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, in addition to above-mentioned necessary raw material, also may be used
Add auxiliary material, such as, NMF, surfactant, ultraviolet ray-resistant material, alcohols, water etc. according to actual needs.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, can make with conventional base-material and washes by arbitrary proportion
Hair care product, hair shampoo article formulation can be the one in solution, suspension, emulsion, paste, essential oil, spray.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, natural former by multiple gentleness of said composition
Material is made.The present invention carries out the design of herbal mixture according to the theory of traditional Chinese medical science of monarch, with snake woman's leaf as monarch drug in a prescription, takes it and dispels
Wind dampness removing;Clearing heat and detoxicating effect, has the most antibacterial and antiinflammation.With radices trichosanthis and shaggy-fruited dittany as ministerial drug, take radices trichosanthis heat-clearing
Rush down effect of fire;Taking shaggy-fruited dittany to dispel pathogenic wind and remove dampness, clearing heat and detoxicating effect, both of which has obvious antifungic action, strengthens monarch drug in a prescription
Effectiveness.With blue gum and quassia as adjutant, take effect of blue gum expelling wind and removing dampness;Take quassia clearing heat and detoxicating;Effect of removing dampness and destroying parasites,
Monarch, ministerial drug is assisted to play the effect of effect.With wrinkled giant hyssop for making medicine, take wrinkled giant hyssop and deliver antipyretic effect, coordinating the drug actions of a prescription.The most all
Medicine reasonable compatibility, mutually coordinated, play the effect of anti-dandruff and itching-relieving reparation altogether, reach the effect treated both principal and secondary aspect of disease, this Chinese medicine composition simultaneously
Anti-dandruff effective, speed is fast, and drug effect is gentle, has no side effect, and is suitable for all kinds of hair qualitys.
Further, the invention provides the preparation method of a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf,
Its concrete preparation process is as follows:
1, pulverize after radices trichosanthis, snake woman's leaf, shaggy-fruited dittany, blue gum, quassia being separately dried, extract and concentrate, obtain snakegourd
Root extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract, quassia extract;
2, the radices trichosanthis extract of step 1 gained, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract, quassia are carried
Take liquid and carry out maturation process respectively, carry out after cooling filtering, purifying to obtain each raw material Essence, each raw material Essence is mixed,
Add wrinkled giant hyssop, after dissolving, again carry out filtering, purifying, obtain mixing Essence;
3, mixing Essence step 2 obtained carries out homogeneous, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing snake woman's leaf
Compound.
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, wherein to Chinese juniper in step 1
Lou Gen, snake woman's leaf, shaggy-fruited dittany, blue gum, the extraction of quassia, method for concentration are conventional plant extract, method for concentration, can be by
Effective medical active composition in plant is separated, and increases activity component concentration, improves anti-dandruff effect.
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, wherein to Chinese juniper in step 2
Building root extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract, quassia extract carry out maturation process respectively,
I.e. carry out plant extraction liquid heating pressurized treatments, destroy the easy allergin in extract, reduce side effect, improve difference
The adaptability of skin quality, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve and skin is oozed
Speed thoroughly.
Wherein, in described curing process, the cooking conditions to each raw material is different, can farthest ensure effective anti-dandruff activity
Under the reactive conditions of material, destroy the easy allergin in extract, reduce side effect, and by active component bigger for molecular weight
Resolve into the active component of molecular weight, improve the seepage velocity to skin, its temperature, pressure and time specifically chosen such as
Under:
Material name | Curing temperature (DEG C) | Curing pressure (MPa) | Time (h) |
Radices trichosanthis | 75-80 | 0.1-0.2 | 1-2 |
Snake woman's leaf | 75-80 | 0.1-0.2 | 1-2 |
Shaggy-fruited dittany | 70-75 | 0.1-0.2 | 1-2 |
Blue gum | 65-70 | 0.1-0.2 | 2-3 |
Quassia | 55-60 | 0.1-0.2 | 0.5-1 |
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, by carrying different material
Take liquid curing at different conditions, the easy allergin in raw material extract is inactivated or decomposes, and retain energy Synergistic
Effectively medicinal active ingredient, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, thus not only drop
The low allergy probability of Chinese medicine composition, improves adaptability, moreover it is possible to improve skin-permeation rate, and anti-dandruff effect is more preferable, more
Hurry up.
Compared with prior art, beneficial effects of the present invention:
1, the present composition passes through the rational compatibility of each raw material, makes different effective active compositions produce synergistic function, pole
The big property of medicine exciting effective active matter, anti-dandruff effective, faster.
2, the present composition selects multiple gentle raw material, and formulated by optimal compatibility, drug effect is gentle, has no side effect.
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, the infiltration to scalp
Property more preferable, improve anti-dandruff speed.
4, the easy allergin in raw material extract is processed by the present composition by curing process, reduces easy anaphylaxis
And side reaction, improve the adaptability of composition.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should be interpreted as this
The scope of bright above-mentioned theme is only limitted to below example, and all technology realized based on present invention belong to the model of the present invention
Enclose.
Embodiment 1
1, by radices trichosanthis 12 parts, 20 parts of snake woman's leaf, shaggy-fruited dittany 9 parts, blue gum 7 parts, quassia 5 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain radices trichosanthis extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract,
Quassia extract;
2, by the radices trichosanthis extract of step 1 gained at 78 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 1h,
Cool down to obtain radices trichosanthis Essence;By snake woman's leaf extract of step 1 gained at 78 DEG C, carry out under 0.2Mpa pressure curing 1h
After carry out filtering, purifying, cool down to obtain snake woman's leaf Essence;By the shaggy-fruited dittany extract of step 1 gained at 73 DEG C, 0.1Mpa
Carry out filtering, purifying after carrying out under pressure curing 2h, cool down to obtain shaggy-fruited dittany Essence;The blue gum extract of step 1 gained is existed
70 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 2h, cool down to obtain blue gum Essence;By step 1 gained
Quassia extract, at 58 DEG C, carries out filtering, purifying after carrying out curing 0.5h, cool down to obtain quassia Essence under 0.2Mpa pressure;
The radices trichosanthis Essence of gained, snake woman's leaf Essence, shaggy-fruited dittany Essence, blue gum Essence, quassia Essence are mixed,
Add 0.3 portion of wrinkled giant hyssop, after dissolving, again purify, obtain mixing Essence;
3, mixing Essence step 2 obtained carries out homogeneous, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing snake woman's leaf
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the cluster bean of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Embodiment 2
1, by radices trichosanthis 16 parts, 25 parts of snake woman's leaf, shaggy-fruited dittany 6 parts, blue gum 4 parts, quassia 7 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain radices trichosanthis extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract,
Quassia extract;
2, by the radices trichosanthis extract of step 1 gained at 75 DEG C, carry out filtering, purifying after carrying out under 0.1Mpa pressure curing 2h,
Cool down to obtain radices trichosanthis Essence;By snake woman's leaf extract of step 1 gained at 70 DEG C, carry out under 0.2Mpa pressure curing 1h
After carry out filtering, purifying, cool down to obtain snake woman's leaf Essence;By the shaggy-fruited dittany extract of step 1 gained at 75 DEG C, 0.1Mpa
Carry out filtering, purifying after carrying out under pressure curing 2h, cool down to obtain shaggy-fruited dittany Essence;The blue gum extract of step 1 gained is existed
65 DEG C, carry out filtering, purifying after carrying out under 0.1Mpa pressure curing 3h, cool down to obtain blue gum Essence;By step 1 gained
Quassia extract, at 60 DEG C, carries out filtering, purifying after carrying out curing 0.5h, cool down to obtain quassia Essence under 0.2Mpa pressure;
The radices trichosanthis Essence of gained, snake woman's leaf Essence, shaggy-fruited dittany Essence, blue gum Essence, quassia Essence are mixed,
Add 0.5 portion of wrinkled giant hyssop, after dissolving, again purify, obtain mixing Essence;
3, mixing Essence step 2 obtained carries out homogeneous, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing snake woman's leaf
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the cluster bean of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Embodiment 3
1, by radices trichosanthis 8 parts, 15 parts of snake woman's leaf, shaggy-fruited dittany 12 parts, blue gum 9 parts, quassia 3 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain radices trichosanthis extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract,
Quassia extract;
2, by the radices trichosanthis extract of step 1 gained at 70 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 1h,
Cool down to obtain radices trichosanthis Essence;By snake woman's leaf extract of step 1 gained at 75 DEG C, carry out under 0.2Mpa pressure curing 1h
After carry out filtering, purifying, cool down to obtain snake woman's leaf Essence;By the shaggy-fruited dittany extract of step 1 gained at 70 DEG C, 0.1Mpa
Carry out filtering, purifying after carrying out under pressure curing 2h, cool down to obtain shaggy-fruited dittany Essence;The blue gum extract of step 1 gained is existed
65 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 2h, cool down to obtain blue gum Essence;By step 1 gained
Quassia extract, at 55 DEG C, carries out filtering, purifying after carrying out curing 1h, cool down to obtain quassia Essence under 0.1Mpa pressure;Will
The radices trichosanthis Essence of gained, snake woman's leaf Essence, shaggy-fruited dittany Essence, blue gum Essence, quassia Essence mix,
Add 0.2 portion of wrinkled giant hyssop, after dissolving, again purify, obtain mixing Essence;
3, mixing Essence step 2 obtained carries out homogeneous, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing snake woman's leaf
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the cluster bean of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Comparative example 1
1, by radices trichosanthis 12 parts, shaggy-fruited dittany 9 parts, blue gum 7 parts, quassia 5 parts is pulverized after being separately dried, is carried out with ethanol solution
Extract and concentrate, obtain radices trichosanthis extract, shaggy-fruited dittany extract, blue gum extract, quassia extract;
2, by the radices trichosanthis extract of step 1 gained at 78 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 1h,
Cool down to obtain radices trichosanthis Essence;By the shaggy-fruited dittany extract of step 1 gained at 73 DEG C, carry out curing 2h under 0.1Mpa pressure laggard
Row filters, purifies, and cools down to obtain shaggy-fruited dittany Essence;By the blue gum extract of step 1 gained at 70 DEG C, carry out under 0.2Mpa pressure
Carry out filtering, purifying after curing 2h, cool down to obtain blue gum Essence;By the quassia extract of step 1 gained at 58 DEG C, 0.2Mpa
Carry out filtering, purifying after carrying out under pressure curing 0.5h, cool down to obtain quassia Essence;By the radices trichosanthis Essence of gained, shaggy-fruited dittany
Essence, blue gum Essence, quassia Essence mix, and add 0.3 portion of wrinkled giant hyssop, after dissolving, again purify,
Essence must be mixed;
3, mixing Essence step 2 obtained carries out homogeneous, the anti-dandruff Chinese medicine composition for cosmetics obtained;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the cluster bean of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 2
1, by 20 parts of snake woman's leaf, shaggy-fruited dittany 9 parts, blue gum 7 parts, quassia 5 parts is pulverized after being separately dried, is entered with ethanol solution
Row extracts and concentrates, and obtains snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract, quassia extract;
2, by snake woman's leaf extract of step 1 gained at 78 DEG C, carry out filtering, carrying after carrying out under 0.2Mpa pressure curing 1h
Pure, cool down to obtain snake woman's leaf Essence;By the shaggy-fruited dittany extract of step 1 gained at 73 DEG C, cure under 0.1Mpa pressure
Carry out after 2h filtering, purifying, cool down to obtain shaggy-fruited dittany Essence;By the blue gum extract of step 1 gained at 70 DEG C, 0.2Mpa presses
Carry out filtering, purifying after carrying out under power curing 2h, cool down to obtain blue gum Essence;By the quassia extract of step 1 gained at 58 DEG C,
Carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 0.5h, cool down to obtain quassia Essence;By snake woman's folic acid China of gained
Liquid, shaggy-fruited dittany Essence, blue gum Essence, quassia Essence mix, and add 0.3 portion of wrinkled giant hyssop, after dissolving, again enter
Row purifies, and obtains mixing Essence;
3, mixing Essence step 2 obtained carries out homogeneous, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing snake woman's leaf
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the cluster bean of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 3
1, by radices trichosanthis 12 parts, 20 parts of snake woman's leaf, shaggy-fruited dittany 9 parts, blue gum 7 parts, pulverize after being separately dried, molten with ethanol
Liquid extracts and concentrates, and obtains radices trichosanthis extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract;
2, by the radices trichosanthis extract of step 1 gained at 78 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 1h,
Cool down to obtain radices trichosanthis Essence;By snake woman's leaf extract of step 1 gained at 78 DEG C, carry out under 0.2Mpa pressure curing 1h
After carry out filtering, purifying, cool down to obtain snake woman's leaf Essence;By the shaggy-fruited dittany extract of step 1 gained at 73 DEG C, 0.1Mpa
Carry out filtering, purifying after carrying out under pressure curing 2h, cool down to obtain shaggy-fruited dittany Essence;The blue gum extract of step 1 gained is existed
70 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 2h, cool down to obtain blue gum Essence;By the radices trichosanthis of gained
Essence, snake woman's leaf Essence, shaggy-fruited dittany Essence, blue gum Essence mix, and add 0.3 portion of wrinkled giant hyssop, after dissolving,
Again purify, obtain mixing Essence;
3, mixing Essence step 2 obtained carries out homogeneous, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing snake woman's leaf
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the cluster bean of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 4
1, by radices trichosanthis 20 parts, 10 parts of snake woman's leaf, shaggy-fruited dittany 15 parts, blue gum 3 parts, quassia 2 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain radices trichosanthis extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract,
Quassia extract;
2, by the radices trichosanthis extract of step 1 gained at 78 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 1h,
Cool down to obtain radices trichosanthis Essence;By snake woman's leaf extract of step 1 gained at 78 DEG C, carry out under 0.2Mpa pressure curing 1h
After carry out filtering, purifying, cool down to obtain snake woman's leaf Essence;By the shaggy-fruited dittany extract of step 1 gained at 73 DEG C, 0.1Mpa
Carry out filtering, purifying after carrying out under pressure curing 2h, cool down to obtain shaggy-fruited dittany Essence;The blue gum extract of step 1 gained is existed
70 DEG C, carry out filtering, purifying after carrying out under 0.2Mpa pressure curing 2h, cool down to obtain blue gum Essence;By step 1 gained
Quassia extract, at 58 DEG C, carries out filtering, purifying after carrying out curing 0.5h, cool down to obtain quassia Essence under 0.2Mpa pressure;
The radices trichosanthis Essence of gained, snake woman's leaf Essence, shaggy-fruited dittany Essence, blue gum Essence, quassia Essence are mixed,
Add 0.3 portion of wrinkled giant hyssop, after dissolving, again purify, obtain mixing Essence;
3, mixing Essence step 2 obtained carries out homogeneous, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing snake woman's leaf
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the cluster bean of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 5
1, by radices trichosanthis 12 parts, 20 parts of snake woman's leaf, shaggy-fruited dittany 9 parts, blue gum 7 parts, quassia 5 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain radices trichosanthis extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract,
Quassia extract;
2, the radices trichosanthis extract of step 1 gained, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract, quassia are carried
Take liquid to mix, add 0.3 portion of wrinkled giant hyssop, after dissolving, again purify, obtain mixing Essence;
3, mixing Essence step 2 obtained carries out homogeneous, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing snake woman's leaf
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the cluster bean of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Test example minimal inhibitory concentration (MIC) is tested
Take the culture dish containing different components concentration gradient, draw 0.1mL chlosma with aseptic straw and be added drop-wise to above-mentioned culture dish
In, smoothen with aseptic L-type glass bar, at 37 DEG C, cultivate 24h, with sterilized water, blank extract and composition diluent
Compare, record observed result.MIC with the least concentration entirely without thalli growth as said composition.And with pyrithione zinc
As positive control, it is 20mg/L to the MIC of chlosma.Test procedure reference [Zheng Jiaqi, Li Jiahong. clinical bacteriology.
Beijing: People's Health Publisher, 1986,11-12,367-368].Testing result is shown in Table 1.
The dandruff control shampoo containing that above-described embodiment 1-3 and comparative example 1-5 obtain is tried out, randomly chooses 40 potential head bits patients'
Volunteer, is divided into 8 groups, uses the shampoo that embodiment and comparative example prepare respectively, its anti-dandruff effect is carried out detection and
Evaluating, wherein symptom eliminates and disappears for dandruff, without scratchiness.Record the results are shown in Table shown in 1:
Table 1
From above proof test data, 1-3 group (embodiment 1-3) have employed present composition raw material composition and joins
The anti-dandruff Chinese medicine composition that side prepares, has synergistic function, and anti-dandruff effect is notable, and speed is fast, and continuous and effective,
The chlosma that can cause dandruff had good inhibition.4th group (comparative example 1) does not adds monarch drug in a prescription snake woman's leaf,
Composition compatibility changes completely, and drug effect changes, and the MIC value of composition becomes 450mg/L, suppresses chlosma weak effect, goes
Bits poor effect;5th group (comparative example 2) does not adds ministerial drug radices trichosanthis, and composition compatibility changes, and loses collaborative between medicinal material
Synergistic effect, the MIC value of composition becomes 350mg/L, and suppression chlosma effect is deteriorated, and anti-dandruff effect is deteriorated;6th group
(comparative example 3) does not adds adjutant quassia, and composition compatibility changes, and loses synergistic function, the MIC of composition between medicinal material
Value becomes 312mg/L, and suppression chlosma effect is deteriorated, and anti-dandruff effect is deteriorated;7th group (comparative example 4) does not use this
The raw material number of inventive composition, compatibility changes, and radices trichosanthis becomes monarch drug in a prescription, and snake woman's leaf becomes ministerial drug, the group prepared
The overall property of medicine of compound changes, and also loses synergistic function between medicinal material, and anti-dandruff effect is deteriorated;8th group (comparative example 5) does not has
There is the method using the present invention to prepare composition, there is preferable anti-dandruff effect equally, but the onset of drug effect slows, anti-dandruff
Time is elongated.
Claims (9)
1. the anti-dandruff Chinese medicine composition for cosmetics containing snake woman's leaf, it is characterised in that described composition is by following heavy
The raw material of amount part proportioning is prepared from: radices trichosanthis 8-16 part, snake woman's leaf 15-25 part, shaggy-fruited dittany 6-12 part, blue gum 4-9 part,
Wrinkled giant hyssop 0.2-0.5 part, quassia 3-7 part.
Chinese medicine composition the most according to claim 1, it is characterised in that described composition is by the raw material system of following weight
Standby: radices trichosanthis 10-14 part, snake woman's leaf 18-22 part, shaggy-fruited dittany 8-10 part, blue gum 5-8 part, wrinkled giant hyssop 0.2-0.4 part,
Quassia 4-6 part.
Chinese medicine composition the most according to claim 2, it is characterised in that described composition is by the raw material system of following weight
Standby: radices trichosanthis 12 parts, 20 parts of snake woman's leaf, shaggy-fruited dittany 9 parts, blue gum 7 parts, wrinkled giant hyssop 0.3 part, quassia 5 parts.
4. according to Chinese medicine composition described in any one of claim 1-3, it is characterised in that the preparation method of described Chinese medicine composition, its
Concrete preparation process is as follows:
(1), radices trichosanthis, snake woman's leaf, shaggy-fruited dittany, blue gum, quassia are separately dried after pulverize, extract and concentrate,
Radices trichosanthis extract, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract, quassia extract;
(2), by the radices trichosanthis extract of step 1 gained, snake woman's leaf extract, shaggy-fruited dittany extract, blue gum extract, hardship
Wood extract carries out maturation process respectively, carries out filtering, purifying to obtain each raw material Essence after cooling, is mixed by each raw material Essence
Uniformly, add wrinkled giant hyssop, after dissolving, again carry out filtering, purifying, obtain mixing Essence;
(3) the mixing Essence, by step 2 obtained carries out homogeneous, obtain containing snake woman's leaf for cosmetics anti-dandruff in
Drug composition.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described composition, radices trichosanthis
The curing temperature of extract is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described composition, snake woman
The curing temperature of leaf extract is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described composition, shaggy-fruited dittany carries
Take the curing temperature of thing be 70-75 DEG C, pressure be 0.1-0.2Mpa, the time be 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described composition, blue gum carries
Take the curing temperature of liquid be 65-70 DEG C, pressure be 0.1-0.2Mpa, the time be 2-3h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described composition, quassia carries
Take the curing temperature of liquid be 55-60 DEG C, pressure be 0.1-0.2Mpa, the time be 0.5-1h.
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CN107184528A (en) * | 2017-05-22 | 2017-09-22 | 朱雅玲 | A kind of whitening emulsion and preparation method thereof |
GB2558341A (en) * | 2016-09-06 | 2018-07-11 | Henkel Ag & Co Kgaa | Oxidative hair dye with optimized lift performance |
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CN102614102A (en) * | 2012-04-27 | 2012-08-01 | 昆明远方生物制品有限公司 | Dandruff-removing medicinal composition and preparation method thereof |
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Cited By (5)
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GB2558341A (en) * | 2016-09-06 | 2018-07-11 | Henkel Ag & Co Kgaa | Oxidative hair dye with optimized lift performance |
US10285931B2 (en) | 2016-09-06 | 2019-05-14 | Henkel Ag & Co. Kgaa | Oxidative hair dye with optimized lift performance |
GB2558341B (en) * | 2016-09-06 | 2021-10-20 | Henkel Ag & Co Kgaa | Oxidative hair dye with optimized lift performance |
CN107184528A (en) * | 2017-05-22 | 2017-09-22 | 朱雅玲 | A kind of whitening emulsion and preparation method thereof |
CN107184528B (en) * | 2017-05-22 | 2021-04-23 | 广东珍宝健康日用品科技有限公司 | Whitening emulsion and preparation method thereof |
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