CN105919884A - Anti-dandruff traditional Chinese medicine composition containing Adiantum leaf and for cosmetics - Google Patents
Anti-dandruff traditional Chinese medicine composition containing Adiantum leaf and for cosmetics Download PDFInfo
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- CN105919884A CN105919884A CN201610414895.2A CN201610414895A CN105919884A CN 105919884 A CN105919884 A CN 105919884A CN 201610414895 A CN201610414895 A CN 201610414895A CN 105919884 A CN105919884 A CN 105919884A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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Abstract
The invention discloses an anti-dandruff traditional Chinese medicine composition containing Adiantum leaf and for cosmetics. The composition is prepared from, by weight, 8-16 parts of Gentiana manshurica, 15-25 parts of Adiantum leaf, 6-12 parts of Rhizoma belamcandae, 4-9 parts of Rhizoma cimicifugae, 0.2-0.5 part of Rhizoma coptidis and 3-7 parts of Radix helenii. Combining of raw materials is optimized to enable the raw materials to be synergistic, so that anti-dandruff effect of the composition is improved; the composition is mild in efficacy, is composed of pure natural plant extracts and is little in side effect, high in adaptability and low in cost.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf.
Background technology
Under normal circumstances, the epidermis cell at scalp, owing to the cell of those basal layeres is ceaselessly bred, and release to surface,
These cell maturations last, become and do not have lived horny layer to come off.When scalp is the most healthy, the cell come off be we not
The powder easily discovered, the most just can't see the dandruff.But when scalp goes wrong, epidermal area cannot be ripe, then well
Peel off large stretch ofly, here it is the dandruff.
Dandruff Producing reason mainly has two aspects: one is the funguses such as microorganism such as chlosma and antibacterial infects and causes corium
Cell division is accelerated；Two is that sebum secretion is the most vigorous, and sebum is attached on scalp together with the cell come off, and reforms into after drying
The dandruff in small, broken bits.So, anti-dandruff the best way is exactly growth and the suppression sebum secretion suppressing microorganism.
The Effect raw material that at present dandruff control shampoo containing of commercial type is added mainly include salicylic acid, pyrithione zinc, ketoconazole,
One or more in climbazole and pyridone ethanolamine, these anti-dandruff agent mainly reach anti-dandruff purpose by suppression microorganism.
These anti-dandruff agent are the material of chemosynthesis, and relatively big to the zest of human body, the dandruff control shampoo containing containing above-mentioned raw materials has
Also scalp is caused while anti-dandruff effect certain injury.Along with scientific and technological development, growth in the living standard and hair quality is good for
The raising of Kang Yishi, people are more and more higher to the attention rate of shampoo, and Chinese medicine natural, green, safe and effective is anti-dandruff to be washed
Flood and particularly receive publicity.Dandruff control shampoo containing traditional Chinese medicines is little with its toxic and side effects, and the occupancy volume of the market share expands year by year, but logical
It is commonly present the problems such as curative effect is rapid not, effective ingredient is inconspicuous.
Summary of the invention
It is an object of the invention to overcome the anti-dandruff weak effect in the presence of existing anti-dandruff Chinese medicine composition technology, anti-dandruff take effect slow
Not enough, it is provided that a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf.Said composition is joined by optimizing materials
5, make to produce between raw medicinal material synergistic function, add the anti-dandruff effect of compositions and the speed that takes effect, drug effect is gentle；
Said composition is combined by pure natural plant extract, and side effect is little, and wide adaptability is with low cost.
In order to realize foregoing invention purpose, the invention provides a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf
Thing, said composition is to be prepared from by the raw material of following weight: Gentiana manshurica 8-16 part, iron wire fern leaf 15-25 part,
Rhizoma Belamcandae 6-12 part, Rhizoma Cimicifugae 4-9 part, Rhizoma Coptidis 0.2-0.5 part, Radix Inulae 3-7 part.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, wherein said Gentiana manshurica, nature and flavor are bitter,
Cold；Return liver, spleen channel, there is heat clearing and damp drying, effect of eliminating pathogen in the liver gallbladder fire.It is mainly used in treating jaundice due to damp-heat, swelling of the vulva pudendal pruritus, band
Lower disease, persistent erection of the penis, eczema pruritus, conjunctival congestion, deaf, swell and ache, convulsion with spasms.
Wherein said iron wire fern leaf, nature and flavor are light, bitter, cool；GUIXIN, kidney, lung meridian；There is heat-clearing and toxic substances removing, inducing diuresis and reducing edema,
Effect of inducing diuresis for treating stranguria syndrome；It is mainly used in treating dysentery, scrofula, cough due to lung-heat, hepatitis, stranguria, venom, traumatic injury.
Wherein said Rhizoma Belamcandae, bitter in the mouth, cold in nature；Return lung, liver, spleen channel；Have heat-clearing and toxic substances removing, eliminating stagnation antiinflammatory, reducing swelling and alleviating pain,
Effect of relieving cough and resolving phlegm；It is mainly used in treating accumulation and obstruction of sputum, the disease such as cough and asthma.Laryngopharynx swelling and pain, sore throat is obstructed, constipation and anuresis,
All medicines are not imitated, abdominal part hydrops, skin turn black, acute mastitis from the beginning of
Wherein said Rhizoma Cimicifugae, nature and flavor are pungent, sweet, are slightly cold；Return lung, spleen, large intestine, stomach warp；Have and deliver rash, heat clearing away solution
Poison, effect of ascending up spleen-Qi and Yang, it is mainly used in treating seasonal epidemic pathogens epidemic disease, cold and heat of having a headache, laryngalgia, aphtha, macule is impermeable；Under middle gas
Falling into, chronic diarrhea chronic dysentery, proctoptosis, women is collapsed, is carried, and uterus drops；Carbuncle sore tumefacting virus.
Wherein said Rhizoma Coptidis, nature and flavor are bitter, cold.Return lung, stomach, kidney channel；There is heat clearing and damp drying, effect of eliminating fire and detoxication；Main
It is used for treating damp and hot feeling of fullness, vomits acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed,
Conjunctival congestion, toothache, quench one's thirst, carbuncle furuncle；External treatment eczema, eczema, auditory meatus is suppurated.
Wherein said Radix Inulae, nature and flavor: arduous, temperature；Return lung, liver, spleen channel；There is invigorating the spleen and regulating the stomach, the merit of promoting the circulation of QI to relieve pain
Effect；Being mainly used in treating the breast side of body, abdominal distention, vomiting dysentery, the breast side of body is dampened, and feels a pain in the chest when breathing and has a pain, frequent fetal movement.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, it is preferred that said composition is by following heavy
The raw material of amount part proportioning is prepared from: Gentiana manshurica 10-14 part, iron wire fern leaf 18-22 part, Rhizoma Belamcandae 8-10 part, Rhizoma Cimicifugae 5-8
Part, Rhizoma Coptidis 0.2-0.4 part, Radix Inulae 4-6 part；It is further preferred that said composition is by the raw material system of following weight
Standby: Gentiana manshurica 12 parts, iron wire fern leaf 20 parts, Rhizoma Belamcandae 9 parts, Rhizoma Cimicifugae 7 parts, Rhizoma Coptidis 0.3 part, Radix Inulae 5
Part.Preferably can make the synergistic function maximum of compositions by above-mentioned, anti-dandruff effect reaches optimal, and side effect is minimum.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, in addition to above-mentioned necessary raw material, also may be used
Add auxiliary material, such as, wetting agent, surfactant, ultraviolet ray-resistant material, alcohols, water etc. according to actual needs.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, can make with conventional base material and washes by arbitrary proportion
Hair care product, hair shampoo article dosage form can be the one in solution, suspension, emulsion, paste, quintessence oil, spray.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, natural former by multiple gentleness of said composition
Material is made.The present invention carries out the design of herbal mixture according to the theory of Chinese medical science of monarch, with iron wire fern leaf as monarch drug, takes it clear
Thermal detoxification, inducing diuresis and reducing edema effect, there is the most antibacterial and antiinflammation.With Gentiana manshurica and Rhizoma Belamcandae as ministerial drug, take Gentiana manshurica
Heat clearing and damp drying, eliminating pathogen in the liver gallbladder effect of fire；Taking effect of Rhizoma Belamcandae heat-clearing and toxic substances removing, both of which has obvious antifungic action, strengthens
The effectiveness of monarch drug.With Rhizoma Cimicifugae and Radix Inulae as adjuvant drug, take Rhizoma Cimicifugae and deliver rash, effect of heat-clearing and toxic substances removing；Fetch earth Radix Aucklandiae spleen invigorating and
Stomach, effect of promoting the circulation of QI to relieve pain, assist monarch, ministerial drug to play the effect of effect.With Rhizoma Coptidis for making medicine, take Rhizoma Coptidis heat clearing and damp drying, rush down
Effect of fire removing toxic substances, coordinating the actions of various ingredients in a prescription.The most all medicine reasonable compatibilities, mutually coordinated, play the effect of removing scurf and relieving itching reparation altogether, reach simultaneously
To the effect for the treatment of both the principal and secondary aspects of a disease, this Chinese medicine composition is anti-dandruff effective, and speed is fast, and drug effect is gentle, has no side effect, and is suitable for all kinds of
Hair quality.
Further, the invention provides the preparation method of a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf,
Its concrete preparation process is as follows:
1, pulverize after Gentiana manshurica, iron wire fern leaf, Rhizoma Belamcandae, Rhizoma Cimicifugae, Radix Inulae being separately dried, extract and concentrate,
Gentiana manshurica extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution, Radix Inulae extracting solution；
2, by the Gentiana manshurica extracting solution of step 1 gained, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution, building
Fragrant extracting solution carries out maturation process respectively, carries out filtering, purifying to obtain each raw material essence after cooling, is mixed by each raw material essence
Uniformly, add Rhizoma Coptidis, after dissolving, again carry out filtering, purifying, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing iron wire fern leaf
Compound.
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, wherein to bar in step 1
Leaf Radix Gentianae, iron wire fern leaf, Rhizoma Belamcandae, Rhizoma Cimicifugae, the extraction of Radix Inulae, method for concentration are conventional plant extract, method for concentration,
Effective medical active composition in plant can be separated, and increase activity component concentration, improve anti-dandruff effect.
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, wherein to bar in step 2
Leaf Radix Gentianae extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution, Radix Inulae extracting solution are carried out at ripening respectively
Reason, i.e. carries out plant extraction liquid heating pressurized treatments, destroys the easy allergin in extracting solution, reduce side effect, and it is right to improve
The adaptability of different skin quality, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve skin
Seepage velocity.
Wherein, in described curing process, the cooking conditions to each raw material is different, can farthest ensure effective anti-dandruff activity
Under the reactive conditions of material, destroy the easy allergin in extracting solution, reduce side effect, and by active component bigger for molecular weight
Resolve into the active component of molecular weight, improve the seepage velocity to skin, its temperature, pressure and time specifically chosen such as
Under:
| Material name | Curing temperature (DEG C) | Ripening pressure (MPa) | Time (h) |
| Gentiana manshurica | 75-80 | 0.1-0.2 | 1-2 |
| Iron wire fern leaf | 75-80 | 0.1-0.2 | 1-2 |
| Rhizoma Belamcandae | 70-75 | 0.1-0.2 | 1-2 |
| Rhizoma Cimicifugae | 65-70 | 0.1-0.2 | 2-3 |
| Radix Inulae | 55-60 | 0.1-0.2 | 0.5-1 |
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, by carrying different material
Take liquid ripening at different conditions, the easy allergin in raw material extracting solution is inactivated or decomposes, and retain energy Synergistic
Effectively medicinal active ingredient, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, thus not only drop
The low allergy probability of Chinese medicine composition, improves adaptability, moreover it is possible to improve skin-permeation rate, and anti-dandruff effect is more preferable, more
Hurry up.
Compared with prior art, beneficial effects of the present invention:
1, the present composition passes through the rational compatibility of each raw material, makes different effective active compositions produce synergistic function, pole
The big property of medicine exciting effective active matter, anti-dandruff effective, faster.
2, the present composition selects multiple gentle raw material, and formulated by optimal compatibility, drug effect is gentle, has no side effect.
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, the infiltration to scalp
Property more preferable, improve anti-dandruff speed.
4, the easy allergin in raw material extracting solution is processed by the present composition by curing process, reduces easy anaphylaxis
And side reaction, improve the adaptability of compositions.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should be interpreted as this
The scope of bright above-mentioned theme is only limitted to below example, and all technology realized based on present invention belong to the model of the present invention
Enclose.
Embodiment 1
1, by Gentiana manshurica 12 parts, iron wire fern leaf 20 parts, Rhizoma Belamcandae 9 parts, Rhizoma Cimicifugae 7 parts, Radix Inulae 5 parts is separately dried rear powder
Broken, extract with ethanol solution and concentrate, obtaining Gentiana manshurica extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae
Extracting solution, Radix Inulae extracting solution；
2, by the Gentiana manshurica extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, carrying
Pure, cool down to obtain Gentiana manshurica essence；By the venushair fern leaf extract of step 1 gained at 78 DEG C, carry out ripe under 0.2Mpa pressure
Carry out filtering, purifying after changing 1h, cool down to obtain venushair fern leaf essence；By the Rhizoma Belamcandae extracting solution of step 1 gained at 73 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Rhizoma Belamcandae essence；The Rhizoma Cimicifugae extracting solution of step 1 gained is existed
70 DEG C, carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Rhizoma Cimicifugae essence；By step 1 gained
Radix Inulae extracting solution, at 58 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Radix Inulae elite under 0.2Mpa pressure
Liquid；By the Gentiana manshurica essence of gained, venushair fern leaf essence, Rhizoma Belamcandae essence, Rhizoma Cimicifugae essence, Radix Inulae essence
Mix homogeneously, adds 0.3 portion of Rhizoma Coptidis, after dissolving, again purifies, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing iron wire fern leaf
Compound；
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Embodiment 2
1, by Gentiana manshurica 16 parts, iron wire fern leaf 25 parts, Rhizoma Belamcandae 6 parts, Rhizoma Cimicifugae 4 parts, Radix Inulae 7 parts is separately dried rear powder
Broken, extract with ethanol solution and concentrate, obtaining Gentiana manshurica extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae
Extracting solution, Radix Inulae extracting solution；
2, by the Gentiana manshurica extracting solution of step 1 gained at 75 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, carrying
Pure, cool down to obtain Gentiana manshurica essence；By the venushair fern leaf extract of step 1 gained at 70 DEG C, carry out ripe under 0.2Mpa pressure
Carry out filtering, purifying after changing 1h, cool down to obtain venushair fern leaf essence；By the Rhizoma Belamcandae extracting solution of step 1 gained at 75 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Rhizoma Belamcandae essence；The Rhizoma Cimicifugae extracting solution of step 1 gained is existed
65 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Rhizoma Cimicifugae essence；By step 1 gained
Radix Inulae extracting solution, at 60 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Radix Inulae elite under 0.2Mpa pressure
Liquid；By the Gentiana manshurica essence of gained, venushair fern leaf essence, Rhizoma Belamcandae essence, Rhizoma Cimicifugae essence, Radix Inulae essence
Mix homogeneously, adds 0.5 portion of Rhizoma Coptidis, after dissolving, again purifies, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing iron wire fern leaf
Compound；
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Embodiment 3
1, by Gentiana manshurica 8 parts, iron wire fern leaf 15 parts, Rhizoma Belamcandae 12 parts, Rhizoma Cimicifugae 9 parts, Radix Inulae 3 parts is separately dried rear powder
Broken, extract with ethanol solution and concentrate, obtaining Gentiana manshurica extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae
Extracting solution, Radix Inulae extracting solution；
2, by the Gentiana manshurica extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, carrying
Pure, cool down to obtain Gentiana manshurica essence；By the venushair fern leaf extract of step 1 gained at 75 DEG C, carry out ripe under 0.2Mpa pressure
Carry out filtering, purifying after changing 1h, cool down to obtain venushair fern leaf essence；By the Rhizoma Belamcandae extracting solution of step 1 gained at 70 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Rhizoma Belamcandae essence；The Rhizoma Cimicifugae extracting solution of step 1 gained is existed
65 DEG C, carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Rhizoma Cimicifugae essence；By step 1 gained
Radix Inulae extracting solution, at 55 DEG C, carries out after carrying out ripening 1h filtering, purifying, cool down to obtain Radix Inulae essence under 0.1Mpa pressure；
By the Gentiana manshurica essence of gained, venushair fern leaf essence, Rhizoma Belamcandae essence, Rhizoma Cimicifugae essence, the mixing of Radix Inulae essence
Uniformly, add 0.2 portion of Rhizoma Coptidis, after dissolving, again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing iron wire fern leaf
Compound；
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Comparative example 1
1, by Gentiana manshurica 12 parts, Rhizoma Belamcandae 9 parts, Rhizoma Cimicifugae 7 parts, Radix Inulae 5 parts is pulverized after being separately dried, is used ethanol solution
Extract and concentrate, obtain Gentiana manshurica extracting solution, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution, Radix Inulae extracting solution；
2, by the Gentiana manshurica extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, carrying
Pure, cool down to obtain Gentiana manshurica essence；By the Rhizoma Belamcandae extracting solution of step 1 gained at 73 DEG C, under 0.1Mpa pressure, carry out ripening
Carry out after 2h filtering, purifying, cool down to obtain Rhizoma Belamcandae essence；By the Rhizoma Cimicifugae extracting solution of step 1 gained at 70 DEG C, 0.2Mpa presses
Carry out after carrying out ripening 2h under power filtering, purifying, cool down to obtain Rhizoma Cimicifugae essence；The Radix Inulae extracting solution of step 1 gained is existed
58 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Inulae essence；By the bar leaf of gained
Radix Gentianae essence, Rhizoma Belamcandae essence, Rhizoma Cimicifugae essence, Radix Inulae essence mix homogeneously, add 0.3 portion of Rhizoma Coptidis, dissolves
After, again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, the anti-dandruff Chinese medicine composition for cosmetics obtained；
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 2
1, by iron wire fern leaf 20 parts, Rhizoma Belamcandae 9 parts, Rhizoma Cimicifugae 7 parts, Radix Inulae 5 parts is pulverized after being separately dried, is used ethanol solution
Extract and concentrate, obtain venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution, Radix Inulae extracting solution；
2, by the venushair fern leaf extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, carrying
Pure, cool down to obtain venushair fern leaf essence；By the Rhizoma Belamcandae extracting solution of step 1 gained at 73 DEG C, under 0.1Mpa pressure, carry out ripening
Carry out after 2h filtering, purifying, cool down to obtain Rhizoma Belamcandae essence；By the Rhizoma Cimicifugae extracting solution of step 1 gained at 70 DEG C, 0.2Mpa presses
Carry out after carrying out ripening 2h under power filtering, purifying, cool down to obtain Rhizoma Cimicifugae essence；The Radix Inulae extracting solution of step 1 gained is existed
58 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Inulae essence；By the iron wire of gained
Fern leaf essence, Rhizoma Belamcandae essence, Rhizoma Cimicifugae essence, Radix Inulae essence mix homogeneously, add 0.3 portion of Rhizoma Coptidis, dissolves
After, again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing iron wire fern leaf
Compound；
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 3
1, by Gentiana manshurica 12 parts, iron wire fern leaf 20 parts, Rhizoma Belamcandae 9 parts, Rhizoma Cimicifugae 7 parts, pulverize after being separately dried, use ethanol
Solution extracts and concentrates, and obtains Gentiana manshurica extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution；
2, by the Gentiana manshurica extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, carrying
Pure, cool down to obtain Gentiana manshurica essence；By the venushair fern leaf extract of step 1 gained at 78 DEG C, carry out ripe under 0.2Mpa pressure
Carry out filtering, purifying after changing 1h, cool down to obtain venushair fern leaf essence；By the Rhizoma Belamcandae extracting solution of step 1 gained at 73 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Rhizoma Belamcandae essence；The Rhizoma Cimicifugae extracting solution of step 1 gained is existed
70 DEG C, carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Rhizoma Cimicifugae essence；By the bar leaf dragon of gained
Gallbladder essence, venushair fern leaf essence, Rhizoma Belamcandae essence, Rhizoma Cimicifugae essence mix homogeneously, add 0.3 portion of Rhizoma Coptidis, dissolves
After, again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing iron wire fern leaf
Compound；
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 4
1, by Gentiana manshurica 20 parts, iron wire fern leaf 10 parts, Rhizoma Belamcandae 15 parts, Rhizoma Cimicifugae 3 parts, after Radix Inulae 2 parts is separately dried
Pulverize, extract with ethanol solution and concentrate, obtaining Gentiana manshurica extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, liter
Fiber crops extracting solution, Radix Inulae extracting solution；
2, by the Gentiana manshurica extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, carrying
Pure, cool down to obtain Gentiana manshurica essence；By the venushair fern leaf extract of step 1 gained at 78 DEG C, carry out ripe under 0.2Mpa pressure
Carry out filtering, purifying after changing 1h, cool down to obtain venushair fern leaf essence；By the Rhizoma Belamcandae extracting solution of step 1 gained at 73 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Rhizoma Belamcandae essence；The Rhizoma Cimicifugae extracting solution of step 1 gained is existed
70 DEG C, carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Rhizoma Cimicifugae essence；By step 1 gained
Radix Inulae extracting solution, at 58 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Radix Inulae elite under 0.2Mpa pressure
Liquid；By the Gentiana manshurica essence of gained, venushair fern leaf essence, Rhizoma Belamcandae essence, Rhizoma Cimicifugae essence, Radix Inulae essence
Mix homogeneously, adds 0.3 portion of Rhizoma Coptidis, after dissolving, again purifies, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing iron wire fern leaf
Compound；
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 5
1, by Gentiana manshurica 12 parts, iron wire fern leaf 20 parts, Rhizoma Belamcandae 9 parts, Rhizoma Cimicifugae 7 parts, Radix Inulae 5 parts is separately dried rear powder
Broken, extract with ethanol solution and concentrate, obtaining Gentiana manshurica extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae
Extracting solution, Radix Inulae extracting solution；
2, by the Gentiana manshurica extracting solution of step 1 gained, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution, building
Fragrant extracting solution mix homogeneously, adds 0.3 portion of Rhizoma Coptidis, after dissolving, again purifies, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing iron wire fern leaf
Compound；
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Test example minimal inhibitory concentration (MIC) is tested
Take the culture dish containing different components Concentraton gradient, draw 0.1mL chlosma with aseptic straw and be added drop-wise to above-mentioned culture dish
In, smoothen with aseptic L-type Glass rod, at 37 DEG C, cultivate 24h, with sterilized water, blank extracting solution and compositions diluent
Compare, record observed result.MIC with the least concentration entirely without thalli growth as said composition.And with pyrithione zinc
As positive control, it is 20mg/L to the MIC of chlosma.Test procedure reference [Zheng Jiaqi, Li Jiahong. clinical bacteriology.
Beijing: People's Health Publisher, 1986,11-12,367-368].Testing result is shown in Table 1.
The dandruff control shampoo containing that above-described embodiment 1-3 and comparative example 1-5 obtain is tried out, randomly chooses 40 potential head bits patients'
Volunteer, is divided into 8 groups, uses the shampoo that embodiment and comparative example prepare respectively, its anti-dandruff effect is carried out detection and
Evaluating, wherein symptom eliminates and disappears for dandruff, without scratchiness.Record the results are shown in Table shown in 1:
Table 1
From above proof test data, 1-3 group (embodiment 1-3) have employed present composition raw material composition and joins
The anti-dandruff Chinese medicine composition that side prepares, has synergistic function, and anti-dandruff effect is notable, and speed is fast, and continuous and effective,
The chlosma that can cause the dandruff had good inhibition.4th group (comparative example 1) does not adds monarch drug iron wire fern leaf,
Compositions compatibility changes completely, and drug effect changes, and the MIC value of compositions becomes 450mg/L, suppresses chlosma weak effect, goes
Bits poor effect；5th group (comparative example 2) does not adds ministerial drug Gentiana manshurica, and compositions compatibility changes, and loses association between medical material
Same potentiation, the MIC value of compositions becomes 350mg/L, and suppression chlosma effect is deteriorated, and anti-dandruff effect is deteriorated；6th
Group (comparative example 3) does not adds adjuvant drug Radix Inulae, and compositions compatibility changes, and loses synergistic function, compositions between medical material
MIC value become 312mg/L, suppression chlosma effect is deteriorated, and anti-dandruff effect is deteriorated；7th group (comparative example 4) does not has
Using the raw material number of the present composition, compatibility changes, and Gentiana manshurica becomes monarch drug, and iron wire fern leaf becomes ministerial drug, preparation
The overall property of medicine of compositions obtained changes, and also loses synergistic function between medical material, and anti-dandruff effect is deteriorated；8th group of (contrast
Example 5) do not use the method that the present invention prepares compositions, there is preferable anti-dandruff effect equally, but the onset speed of drug effect becomes
Slowly, the anti-dandruff time is elongated.
Claims (9)
1. the anti-dandruff Chinese medicine composition for cosmetics containing iron wire fern leaf, it is characterised in that described compositions is by following heavy
The raw material of amount part proportioning is prepared from: Gentiana manshurica 8-16 part, iron wire fern leaf 15-25 part, Rhizoma Belamcandae 6-12 part, Rhizoma Cimicifugae 4-9
Part, Rhizoma Coptidis 0.2-0.5 part, Radix Inulae 3-7 part.
Chinese medicine composition the most according to claim 1, it is characterised in that described compositions is by the raw material system of following weight
Standby: Gentiana manshurica 10-14 part, iron wire fern leaf 18-22 part, Rhizoma Belamcandae 8-10 part, Rhizoma Cimicifugae 5-8 part, Rhizoma Coptidis 0.2-0.4
Part, Radix Inulae 4-6 part.
Chinese medicine composition the most according to claim 2, it is characterised in that described compositions is by the raw material system of following weight
Standby: Gentiana manshurica 12 parts, iron wire fern leaf 20 parts, Rhizoma Belamcandae 9 parts, Rhizoma Cimicifugae 7 parts, Rhizoma Coptidis 0.3 part, Radix Inulae 5
Part.
4. according to Chinese medicine composition described in any one of claim 1-3, it is characterised in that the preparation method of described Chinese medicine composition, its
Concrete preparation process is as follows:
(1), Gentiana manshurica, iron wire fern leaf, Rhizoma Belamcandae, Rhizoma Cimicifugae, Radix Inulae are separately dried after pulverize, extract and concentrate,
Obtain Gentiana manshurica extracting solution, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution, Radix Inulae extracting solution；
(2), by the Gentiana manshurica extracting solution of step 1 gained, venushair fern leaf extract, Rhizoma Belamcandae extracting solution, Rhizoma Cimicifugae extracting solution,
Radix Inulae extracting solution carries out maturation process respectively, carries out filtering, purifying to obtain each raw material essence, by each raw material essence after cooling
Mix homogeneously, adds Rhizoma Coptidis, after dissolving, again carries out filtering, purifying, obtains mixing essence；
(3) the mixing essence, by step 2 obtained carries out homogenizing, obtain containing iron wire fern leaf for cosmetics anti-dandruff in
Drug composition.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, bar leaf dragon
The curing temperature of gallbladder extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, venushair fern
The curing temperature of leaf extract is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Rhizoma Belamcandae carries
Take the curing temperature of thing be 70-75 DEG C, pressure be 0.1-0.2Mpa, the time be 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Rhizoma Cimicifugae carries
Take the curing temperature of liquid be 65-70 DEG C, pressure be 0.1-0.2Mpa, the time be 2-3h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Radix Inulae
The curing temperature of extracting solution is 55-60 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
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| CN111432796A (en) * | 2017-11-28 | 2020-07-17 | 株式会社爱茉莉太平洋 | Composition for regulating sebum and shrinking pores |
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| WO2003080006A1 (en) * | 2002-03-22 | 2003-10-02 | Gognis Deutschland Gmbh & Co. Kg | Use of extracts from olive trees as anti-dandruff agents |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111432796A (en) * | 2017-11-28 | 2020-07-17 | 株式会社爱茉莉太平洋 | Composition for regulating sebum and shrinking pores |
| US11672753B2 (en) | 2017-11-28 | 2023-06-13 | Amorepacific Corporation | Composition for sebum control and pore minimizing |
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