CN105919885A - Anti-dandruff traditional Chinese medicine composition containing Uncaria macrophylla and for cosmetics - Google Patents
Anti-dandruff traditional Chinese medicine composition containing Uncaria macrophylla and for cosmetics Download PDFInfo
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- CN105919885A CN105919885A CN201610414922.6A CN201610414922A CN105919885A CN 105919885 A CN105919885 A CN 105919885A CN 201610414922 A CN201610414922 A CN 201610414922A CN 105919885 A CN105919885 A CN 105919885A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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Abstract
The invention discloses an anti-dandruff traditional Chinese medicine composition containing Uncaria macrophylla and for cosmetics. The composition is prepared from, by weight, 8-16 parts of Herba artemisiae scopariae, 15-25 parts of Uncaria macrophylla, 6-12 parts of Radix ampelopsis, 4-9 parts of Radix sophorae flavescentis, 0.2-0.5 part of Rhizoma anemarrhenae and 3-7 parts of Clematis armandii. Combining of raw materials is optimized to enable the raw materials to be synergistic, so that anti-dandruff effect of the composition is improved; the composition is mild in efficacy, is composed of pure natural plant extracts and is little in side effect, high in adaptability and low in cost.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae.
Background technology
Under normal circumstances, the epidermis cell at scalp, owing to the cell of those basal layeres is ceaselessly bred, and release to surface,
These cell maturations last, become and do not have lived horny layer to come off.When scalp is the most healthy, the cell come off be we not
The powder easily discovered, the most just can't see the dandruff.But when scalp goes wrong, epidermal area cannot be ripe, then well
Peel off large stretch ofly, here it is the dandruff.
Dandruff Producing reason mainly has two aspects: one is that microorganism (such as the funguses such as chlosma and antibacterial) infection causes very
Chrotoplast division is accelerated;Two is that sebum secretion is the most vigorous, and sebum is attached on scalp together with the cell come off, dried just change
Become the dandruff in small, broken bits.So, anti-dandruff the best way is exactly growth and the suppression sebum secretion suppressing microorganism.
The Effect raw material that at present dandruff control shampoo containing of commercial type is added mainly include salicylic acid, pyrithione zinc, ketoconazole,
One or more in climbazole and pyridone ethanolamine, these anti-dandruff agent mainly reach anti-dandruff purpose by suppression microorganism.
These anti-dandruff agent are the material of chemosynthesis, and relatively big to the zest of human body, the dandruff control shampoo containing containing above-mentioned raw materials has
Also scalp is caused while anti-dandruff effect certain injury.Along with scientific and technological development, growth in the living standard and hair quality is good for
The raising of Kang Yishi, people are more and more higher to the attention rate of shampoo, and Chinese medicine natural, green, safe and effective is anti-dandruff to be washed
Flood and particularly receive publicity.Dandruff control shampoo containing traditional Chinese medicines is little with its toxic and side effects, and the occupancy volume of the market share expands year by year, but logical
It is commonly present the problems such as curative effect is rapid not, effective ingredient is inconspicuous.
Summary of the invention
It is an object of the invention to overcome the anti-dandruff weak effect in the presence of existing anti-dandruff Chinese medicine composition technology, anti-dandruff take effect slow
Not enough, it is provided that a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae.Said composition is joined by optimizing materials
5, make to produce between raw medicinal material synergistic function, add the anti-dandruff effect of compositions and the speed that takes effect, drug effect is gentle;
Said composition is combined by pure natural plant extract, and side effect is little, and wide adaptability is with low cost.
In order to realize foregoing invention purpose, the invention provides a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae
Thing, said composition is to be prepared from by the raw material of following weight: Herba Artemisiae Scopariae 8-16 part, Ramulus Uncariae macrophyllae 15-25 part,
Radix Ampelopsis 6-12 part, Radix Sophorae Flavescentis 4-9 part, Rhizoma Anemarrhenae 0.2-0.5 part, Herba Clematidis Lasiandrae 3-7 part.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, wherein said Herba Artemisiae Scopariae, nature and flavor hardship,
Pungent, cool;Return liver, spleen channel, there is clearing away heat-damp and promoting diuresis, effect of promoting the function of the gallbladder to alleviate jaundice.It is mainly used in treating jaundice, cholecystitis, bladder
Damp and hot, pruritus due to wind pathogen skin ulcer scabies.
Wherein said Ramulus Uncariae macrophyllae, bitter in the mouth, emblem are puckery, cool in nature;GUIXIN, kidney, lung meridian;There is Qinghuo Jiedu, reducing swelling and alleviating pain,
Dispel the wind, effect of venting QI-blood;It is mainly used in treating rheumatic fever arthromyodynia, limbs joint red and swollen heat pain, joint stuffiness, distending pain of the head and eyes.
Wherein said Radix Ampelopsis, nature and flavor are bitter, puckery, cold;Return lung, liver, spleen channel;There is heat-clearing and toxic substances removing;Removing obstruction for relieving pain;Granulation promoting
Effect of sore;It is mainly used in treating sore swollen toxin, scrofula, scalds, eczema, pyrexial malaria, infantile convulsion, dysentery, hemorrhoidal hamorrhage, anal fistula,
Leucorrhea, traumatic injury, traumatic hemorrhage
Wherein said Radix Sophorae Flavescentis, bitter in the mouth, cold in nature;GUIXIN, liver, stomach, large intestine, bladder warp;There is heat clearing and damp drying, parasite killing,
Effect of diuresis, is mainly used in treating hematodiarrhoea, has blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin
Skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.
The wherein said Rhizoma Anemarrhenae, nature and flavor are bitter, cold.Return lung, stomach, kidney channel;There is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription effect;Main
Being used for treating calentura excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat quenches one's thirst, dryness of the intestine constipation.
Wherein said Herba Clematidis Lasiandrae, hardship lightly seasoned, micro-, cold in nature;GUIXIN, small intestinal and bladder warp;Have clearing away heat and promoting diuresis, detumescence,
The effect of stimulating milk secretion of stimulating the menstrual flow;It is mainly used in treating dysuria, urinary tract infection, amenorrhea, galactostasis, rheumatism, stomachache, stranguria
Edema caused by burning pain, damp-heat in lower-JIAO, poliomyelitis sequela.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, it is preferred that said composition is by following heavy
The raw material of amount part proportioning is prepared from: Herba Artemisiae Scopariae 10-14 part, Ramulus Uncariae macrophyllae 18-22 part, Radix Ampelopsis 8-10 part, Radix Sophorae Flavescentis 5-8
Part, Rhizoma Anemarrhenae 0.2-0.4 part, Herba Clematidis Lasiandrae 4-6 part;It is further preferred that said composition is by the raw material system of following weight
Standby: Herba Artemisiae Scopariae 12 parts, Ramulus Uncariae macrophyllae 20 parts, Radix Ampelopsis 9 parts, Radix Sophorae Flavescentis 7 parts, the Rhizoma Anemarrhenae 0.3 part, Herba Clematidis Lasiandrae 5 parts.
Preferably can make the synergistic function maximum of compositions by above-mentioned, anti-dandruff effect reaches optimal, and side effect is minimum.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, in addition to above-mentioned necessary raw material, also may be used
Add auxiliary material, such as, wetting agent, surfactant, ultraviolet ray-resistant material, alcohols, water etc. according to actual needs.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, can make with conventional base material and washes by arbitrary proportion
Hair care product, hair shampoo article dosage form can be the one in solution, suspension, emulsion, paste, quintessence oil, spray.
Above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, natural former by multiple gentleness of said composition
Material is made.The present invention carries out the design of herbal mixture according to the theory of Chinese medical science of monarch, with Ramulus Uncariae macrophyllae as monarch drug, takes it clear
Fire removing toxic substances, dispels the wind, and effect of venting QI-blood has the most antibacterial and antiinflammation.With Herba Artemisiae Scopariae and Radix Ampelopsis as ministerial drug, take Herba Artemisiae Scopariae
Effect of clearing away heat-damp and promoting diuresis;Taking effect of Radix Ampelopsis heat-clearing and toxic substances removing, both of which has obvious antifungic action, strengthens the effectiveness of monarch drug.
With Radix Sophorae Flavescentis and Herba Clematidis Lasiandrae as adjuvant drug, take effect of Radix Sophorae Flavescentis heat clearing and damp drying;Take effect of Herba Clematidis Lasiandrae clearing heat for detumescence, assist monarch, ministerial drug
Play the effect of effect.With the Rhizoma Anemarrhenae for making medicine, take Rhizoma Anemarrhenae clearing away heat-fire, nourshing Yin and drynsessmoistening prescription effect, coordinating the actions of various ingredients in a prescription.The most all medicines
Reasonable compatibility, mutually coordinated, to play the effect of removing scurf and relieving itching reparation altogether, reach the effect for the treatment of both the principal and secondary aspects of a disease simultaneously, this Chinese medicine composition goes
Considering to be worth doing effective, speed is fast, and drug effect is gentle, has no side effect, and is suitable for all kinds of hair qualitys.
Further, the invention provides the preparation method of a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae,
Its concrete preparation process is as follows:
1, pulverize after Herba Artemisiae Scopariae, Ramulus Uncariae macrophyllae, Radix Ampelopsis, Radix Sophorae Flavescentis, Herba Clematidis Lasiandrae being separately dried, extract and concentrate, obtain mattress
Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid, Herba Clematidis Lasiandrae extracting solution;
2, by the Herba Artemisiae Scopariae extracting solution of step 1 gained, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid, Herba Clematidis Lasiandrae
Extracting solution carries out maturation process respectively, carries out filtering, purifying to obtain each raw material essence after cooling, by the mixing of each raw material essence all
Even, add the Rhizoma Anemarrhenae, after dissolving, again carry out filtering, purifying, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing Ramulus Uncariae macrophyllae
Compound.
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, wherein to mattress in step 1
Herba Artemisiae Scopariae, Ramulus Uncariae macrophyllae, Radix Ampelopsis, Radix Sophorae Flavescentis, the extraction of Herba Clematidis Lasiandrae, method for concentration are conventional plant extract, method for concentration, energy
Effective medical active composition in plant is separated, and increases activity component concentration, improve anti-dandruff effect.
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, wherein to mattress in step 2
Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid, Herba Clematidis Lasiandrae extracting solution carry out maturation process respectively,
I.e. carry out plant extraction liquid heating pressurized treatments, destroy the easy allergin in extracting solution, reduce side effect, improve difference
The adaptability of skin quality, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, improve and skin is oozed
Speed thoroughly.
Wherein, in described curing process, the cooking conditions to each raw material is different, can farthest ensure effective anti-dandruff activity
Under the reactive conditions of material, destroy the easy allergin in extracting solution, reduce side effect, and by active component bigger for molecular weight
Resolve into the active component of molecular weight, improve the seepage velocity to skin, its temperature, pressure and time specifically chosen such as
Under:
Material name | Curing temperature (DEG C) | Ripening pressure (MPa) | Time (h) |
Herba Artemisiae Scopariae | 75-80 | 0.1-0.2 | 1-2 |
Ramulus Uncariae macrophyllae | 75-80 | 0.1-0.2 | 1-2 |
Radix Ampelopsis | 70-75 | 0.1-0.2 | 1-2 |
Radix Sophorae Flavescentis | 65-70 | 0.1-0.2 | 2-3 |
Herba Clematidis Lasiandrae | 55-60 | 0.1-0.2 | 0.5-1 |
The preparation method of above-mentioned a kind of anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, by carrying different material
Take liquid ripening at different conditions, the easy allergin in raw material extracting solution is inactivated or decomposes, and retain energy Synergistic
Effectively medicinal active ingredient, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, thus not only drop
The low allergy probability of Chinese medicine composition, improves adaptability, moreover it is possible to improve skin-permeation rate, and anti-dandruff effect is more preferable, more
Hurry up.
Compared with prior art, beneficial effects of the present invention:
1, the present composition passes through the rational compatibility of each raw material, makes different effective active compositions produce synergistic function, pole
The big property of medicine exciting effective active matter, anti-dandruff effective, faster.
2, the present composition selects multiple gentle raw material, and formulated by optimal compatibility, drug effect is gentle, has no side effect.
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, the infiltration to scalp
Property more preferable, improve anti-dandruff speed.
4, the easy allergin in raw material extracting solution is processed by the present composition by curing process, reduces easy anaphylaxis
And side reaction, improve the adaptability of compositions.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should be interpreted as this
The scope of bright above-mentioned theme is only limitted to below example, and all technology realized based on present invention belong to the model of the present invention
Enclose.
Embodiment 1
1, by Herba Artemisiae Scopariae 12 parts, Ramulus Uncariae macrophyllae 20 parts, Radix Ampelopsis 9 parts, Radix Sophorae Flavescentis 7 parts, Herba Clematidis Lasiandrae 5 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid,
Herba Clematidis Lasiandrae extracting solution;
2, by the Herba Artemisiae Scopariae extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Artemisiae Scopariae essence;By the Ramulus Uncariae macrophyllae extracting solution of step 1 gained at 78 DEG C, under 0.2Mpa pressure, carry out ripening 1h
After carry out filtering, purifying, cool down to obtain Ramulus Uncariae macrophyllae essence;By the Radix Ampelopsis extraction solution of step 1 gained at 73 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Radix Ampelopsis essence;The Radix Sophorae Flavescentis extractive liquid of step 1 gained is existed
70 DEG C, carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Sophorae Flavescentis essence;By step 1 gained
Herba Clematidis Lasiandrae extracting solution, at 58 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Herba Clematidis Lasiandrae elite under 0.2Mpa pressure
Liquid;The Herba Artemisiae Scopariae essence of gained, Ramulus Uncariae macrophyllae essence, Radix Ampelopsis essence, Radix Sophorae Flavescentis essence, Herba Clematidis Lasiandrae essence are mixed
Close uniformly, add 0.3 part of Rhizoma Anemarrhenae, after dissolving, again purify, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing Ramulus Uncariae macrophyllae
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Embodiment 2
1, by Herba Artemisiae Scopariae 16 parts, Ramulus Uncariae macrophyllae 25 parts, Radix Ampelopsis 6 parts, Radix Sophorae Flavescentis 4 parts, Herba Clematidis Lasiandrae 7 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid,
Herba Clematidis Lasiandrae extracting solution;
2, by the Herba Artemisiae Scopariae extracting solution of step 1 gained at 75 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying,
Cool down to obtain Herba Artemisiae Scopariae essence;By the Ramulus Uncariae macrophyllae extracting solution of step 1 gained at 70 DEG C, under 0.2Mpa pressure, carry out ripening 1h
After carry out filtering, purifying, cool down to obtain Ramulus Uncariae macrophyllae essence;By the Radix Ampelopsis extraction solution of step 1 gained at 75 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Radix Ampelopsis essence;The Radix Sophorae Flavescentis extractive liquid of step 1 gained is existed
65 DEG C, carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Radix Sophorae Flavescentis essence;By step 1 gained
Herba Clematidis Lasiandrae extracting solution, at 60 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Herba Clematidis Lasiandrae elite under 0.2Mpa pressure
Liquid;The Herba Artemisiae Scopariae essence of gained, Ramulus Uncariae macrophyllae essence, Radix Ampelopsis essence, Radix Sophorae Flavescentis essence, Herba Clematidis Lasiandrae essence are mixed
Close uniformly, add 0.5 part of Rhizoma Anemarrhenae, after dissolving, again purify, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing Ramulus Uncariae macrophyllae
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Embodiment 3
1, by Herba Artemisiae Scopariae 8 parts, Ramulus Uncariae macrophyllae 15 parts, Radix Ampelopsis 12 parts, Radix Sophorae Flavescentis 9 parts, Herba Clematidis Lasiandrae 3 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid,
Herba Clematidis Lasiandrae extracting solution;
2, by the Herba Artemisiae Scopariae extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Artemisiae Scopariae essence;By the Ramulus Uncariae macrophyllae extracting solution of step 1 gained at 75 DEG C, under 0.2Mpa pressure, carry out ripening 1h
After carry out filtering, purifying, cool down to obtain Ramulus Uncariae macrophyllae essence;By the Radix Ampelopsis extraction solution of step 1 gained at 70 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Radix Ampelopsis essence;The Radix Sophorae Flavescentis extractive liquid of step 1 gained is existed
65 DEG C, carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Sophorae Flavescentis essence;By step 1 gained
Herba Clematidis Lasiandrae extracting solution, at 55 DEG C, carries out after carrying out ripening 1h filtering, purifying, cool down to obtain Herba Clematidis Lasiandrae essence under 0.1Mpa pressure;
By the Herba Artemisiae Scopariae essence of gained, Ramulus Uncariae macrophyllae essence, Radix Ampelopsis essence, Radix Sophorae Flavescentis essence, the mixing of Herba Clematidis Lasiandrae essence all
Even, add 0.2 part of Rhizoma Anemarrhenae, after dissolving, again purify, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing Ramulus Uncariae macrophyllae
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
This dandruff control shampoo containing has anti-dandruff effective, and speed is fast, has no side effect, the advantage being suitable for various hair qualitys.
Comparative example 1
1, by Herba Artemisiae Scopariae 12 parts, Radix Ampelopsis 9 parts, Radix Sophorae Flavescentis 7 parts, Herba Clematidis Lasiandrae 5 parts is pulverized after being separately dried, is entered with ethanol solution
Row extracts and concentrates, and obtains Herba Artemisiae Scopariae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid, Herba Clematidis Lasiandrae extracting solution;
2, by the Herba Artemisiae Scopariae extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Artemisiae Scopariae essence;By the Radix Ampelopsis extraction solution of step 1 gained at 73 DEG C, carry out ripening 2h under 0.1Mpa pressure laggard
Row filters, purifies, and cools down to obtain Radix Ampelopsis essence;By the Radix Sophorae Flavescentis extractive liquid of step 1 gained at 70 DEG C, carry out under 0.2Mpa pressure
Carry out after ripening 2h filtering, purifying, cool down to obtain Radix Sophorae Flavescentis essence;By the Herba Clematidis Lasiandrae extracting solution of step 1 gained at 58 DEG C, 0.2Mpa
Carry out after carrying out ripening 0.5h under pressure filtering, purifying, cool down to obtain Herba Clematidis Lasiandrae essence;By the Herba Artemisiae Scopariae essence of gained, in vain
Liana essence, Radix Sophorae Flavescentis essence, Herba Clematidis Lasiandrae essence mix homogeneously, add 0.3 part of Rhizoma Anemarrhenae, after dissolving, again carry
Pure, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, the anti-dandruff Chinese medicine composition for cosmetics obtained;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 2
1, by Ramulus Uncariae macrophyllae 20 parts, Radix Ampelopsis 9 parts, Radix Sophorae Flavescentis 7 parts, Herba Clematidis Lasiandrae 5 parts is pulverized after being separately dried, is used ethanol solution
Extract and concentrate, obtain Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid, Herba Clematidis Lasiandrae extracting solution;
2, by the Ramulus Uncariae macrophyllae extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, carrying
Pure, cool down to obtain Ramulus Uncariae macrophyllae essence;By the Radix Ampelopsis extraction solution of step 1 gained at 73 DEG C, under 0.1Mpa pressure, carry out ripening
Carry out after 2h filtering, purifying, cool down to obtain Radix Ampelopsis essence;By the Radix Sophorae Flavescentis extractive liquid of step 1 gained at 70 DEG C, 0.2Mpa presses
Carry out after carrying out ripening 2h under power filtering, purifying, cool down to obtain Radix Sophorae Flavescentis essence;The Herba Clematidis Lasiandrae extracting solution of step 1 gained is existed
58 DEG C, carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Herba Clematidis Lasiandrae essence;By the great Ye of gained
Ramulus Uncariae Cum Uncis essence, Radix Ampelopsis essence, Radix Sophorae Flavescentis essence, Herba Clematidis Lasiandrae essence mix homogeneously, add 0.3 part of Rhizoma Anemarrhenae, dissolves
After, again purify, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing Ramulus Uncariae macrophyllae
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 3
1, by Herba Artemisiae Scopariae 12 parts, Ramulus Uncariae macrophyllae 20 parts, Radix Ampelopsis 9 parts, Radix Sophorae Flavescentis 7 parts, pulverize after being separately dried, molten with ethanol
Liquid extracts and concentrates, and obtains Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid;
2, by the Herba Artemisiae Scopariae extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Artemisiae Scopariae essence;By the Ramulus Uncariae macrophyllae extracting solution of step 1 gained at 78 DEG C, under 0.2Mpa pressure, carry out ripening 1h
After carry out filtering, purifying, cool down to obtain Ramulus Uncariae macrophyllae essence;By the Radix Ampelopsis extraction solution of step 1 gained at 73 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Radix Ampelopsis essence;The Radix Sophorae Flavescentis extractive liquid of step 1 gained is existed
70 DEG C, carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Sophorae Flavescentis essence;By the Herba Artemisiae Scopariae of gained
Essence, Ramulus Uncariae macrophyllae essence, Radix Ampelopsis essence, Radix Sophorae Flavescentis essence mix homogeneously, add 0.3 part of Rhizoma Anemarrhenae, after dissolving,
Again purify, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing Ramulus Uncariae macrophyllae
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 4
1, by Herba Artemisiae Scopariae 20 parts, Ramulus Uncariae macrophyllae 10 parts, Radix Ampelopsis 15 parts, Radix Sophorae Flavescentis 3 parts, Herba Clematidis Lasiandrae 2 parts is separately dried rear powder
Broken, extract with ethanol solution and concentrate, obtaining Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis carry
Take liquid, Herba Clematidis Lasiandrae extracting solution;
2, by the Herba Artemisiae Scopariae extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying,
Cool down to obtain Herba Artemisiae Scopariae essence;By the Ramulus Uncariae macrophyllae extracting solution of step 1 gained at 78 DEG C, under 0.2Mpa pressure, carry out ripening 1h
After carry out filtering, purifying, cool down to obtain Ramulus Uncariae macrophyllae essence;By the Radix Ampelopsis extraction solution of step 1 gained at 73 DEG C, 0.1Mpa
Carry out after carrying out ripening 2h under pressure filtering, purifying, cool down to obtain Radix Ampelopsis essence;The Radix Sophorae Flavescentis extractive liquid of step 1 gained is existed
70 DEG C, carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Sophorae Flavescentis essence;By step 1 gained
Herba Clematidis Lasiandrae extracting solution, at 58 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Herba Clematidis Lasiandrae elite under 0.2Mpa pressure
Liquid;The Herba Artemisiae Scopariae essence of gained, Ramulus Uncariae macrophyllae essence, Radix Ampelopsis essence, Radix Sophorae Flavescentis essence, Herba Clematidis Lasiandrae essence are mixed
Close uniformly, add 0.3 part of Rhizoma Anemarrhenae, after dissolving, again purify, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing Ramulus Uncariae macrophyllae
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Comparative example 5
1, by Herba Artemisiae Scopariae 12 parts, Ramulus Uncariae macrophyllae 20 parts, Radix Ampelopsis 9 parts, Radix Sophorae Flavescentis 7 parts, Herba Clematidis Lasiandrae 5 parts be separately dried after pulverize,
Extract with ethanol solution and concentrate, obtain Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid,
Herba Clematidis Lasiandrae extracting solution;
2, by the Herba Artemisiae Scopariae extracting solution of step 1 gained, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid, Herba Clematidis Lasiandrae
Extracting solution mix homogeneously, adds 0.3 part of Rhizoma Anemarrhenae, after dissolving, again purifies, obtain mixing essence;
3, mixing essence step 2 obtained carries out homogenizing, obtains the anti-dandruff Chinese drug-treated group for cosmetics containing Ramulus Uncariae macrophyllae
Compound;
4, anti-dandruff Chinese medicine composition that percentage by weight is 10%, the alkyl poly glucoside of 15%, the Guar beans of 5% are taken respectively
Glue hydroxypropyl-trimethyl ammonium chloride, the purified water of 70% make dandruff control shampoo containing.
Test example minimal inhibitory concentration (MIC) is tested
Take the culture dish containing different components Concentraton gradient, draw 0.1mL chlosma with aseptic straw and be added drop-wise to above-mentioned culture dish
In, smoothen with aseptic L-type Glass rod, at 37 DEG C, cultivate 24h, with sterilized water, blank extracting solution and compositions diluent
Compare, record observed result.MIC with the least concentration entirely without thalli growth as said composition.And with pyrithione zinc
As positive control, it is 20mg/L to the MIC of chlosma.Test procedure reference [Zheng Jiaqi, Li Jiahong. clinical bacteriology.
Beijing: People's Health Publisher, 1986,11-12,367-368].Testing result is shown in Table 1.
The dandruff control shampoo containing that above-described embodiment 1-3 and comparative example 1-5 obtain is tried out, randomly chooses 40 potential head bits patients'
Volunteer, is divided into 8 groups, uses the shampoo that embodiment and comparative example prepare respectively, its anti-dandruff effect is carried out detection and
Evaluating, wherein symptom eliminates and disappears for dandruff, without scratchiness.Record the results are shown in Table shown in 1:
Table 1
From above proof test data, 1-3 group (embodiment 1-3) have employed present composition raw material composition and joins
The anti-dandruff Chinese medicine composition that side prepares, has synergistic function, and anti-dandruff effect is notable, and speed is fast, and continuous and effective,
The chlosma that can cause the dandruff had good inhibition.4th group (comparative example 1) does not adds monarch drug Ramulus Uncariae macrophyllae,
Compositions compatibility changes completely, and drug effect changes, and the MIC value of compositions becomes 450mg/L, suppresses chlosma weak effect, goes
Bits poor effect;5th group (comparative example 2) does not adds ministerial drug Herba Artemisiae Scopariae, and compositions compatibility changes, and loses collaborative between medical material
Potentiation, the MIC value of compositions becomes 350mg/L, and suppression chlosma effect is deteriorated, and anti-dandruff effect is deteriorated;6th group
(comparative example 3) does not adds adjuvant drug Herba Clematidis Lasiandrae, and compositions compatibility changes, and loses synergistic function between medical material, compositions
MIC value becomes 312mg/L, and suppression chlosma effect is deteriorated, and anti-dandruff effect is deteriorated;7th group (comparative example 4) does not make
With the raw material number of the present composition, compatibility changes, and Herba Artemisiae Scopariae becomes monarch drug, and Ramulus Uncariae macrophyllae becomes ministerial drug, prepares
The overall property of medicine of compositions change, also lose synergistic function between medical material, anti-dandruff effect is deteriorated;8th group (comparative example 5)
Do not use the method that the present invention prepares compositions, there is preferable anti-dandruff effect equally, but the onset of drug effect slows, and goes
The bits time is elongated.
Claims (9)
1. the anti-dandruff Chinese medicine composition for cosmetics containing Ramulus Uncariae macrophyllae, it is characterised in that described compositions is by following heavy
The raw material of amount part proportioning is prepared from: Herba Artemisiae Scopariae 8-16 part, Ramulus Uncariae macrophyllae 15-25 part, Radix Ampelopsis 6-12 part, Radix Sophorae Flavescentis 4-9 part,
Rhizoma Anemarrhenae 0.2-0.5 part, Herba Clematidis Lasiandrae 3-7 part.
Chinese medicine composition the most according to claim 1, it is characterised in that described compositions is by the raw material system of following weight
Standby: Herba Artemisiae Scopariae 10-14 part, Ramulus Uncariae macrophyllae 18-22 part, Radix Ampelopsis 8-10 part, Radix Sophorae Flavescentis 5-8 part, Rhizoma Anemarrhenae 0.2-0.4 part,
Herba Clematidis Lasiandrae 4-6 part.
Chinese medicine composition the most according to claim 2, it is characterised in that described compositions is by the raw material system of following weight
Standby: Herba Artemisiae Scopariae 12 parts, Ramulus Uncariae macrophyllae 20 parts, Radix Ampelopsis 9 parts, Radix Sophorae Flavescentis 7 parts, the Rhizoma Anemarrhenae 0.3 part, Herba Clematidis Lasiandrae 5 parts.
4. according to Chinese medicine composition described in any one of claim 1-3, it is characterised in that the preparation method of described Chinese medicine composition, its
Concrete preparation process is as follows:
(1), Herba Artemisiae Scopariae, Ramulus Uncariae macrophyllae, Radix Ampelopsis, Radix Sophorae Flavescentis, Herba Clematidis Lasiandrae are separately dried after pulverize, extract and concentrate,
Obtain Herba Artemisiae Scopariae extracting solution, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid, Herba Clematidis Lasiandrae extracting solution;
(2), by the Herba Artemisiae Scopariae extracting solution of step 1 gained, Ramulus Uncariae macrophyllae extracting solution, Radix Ampelopsis extraction solution, Radix Sophorae Flavescentis extractive liquid, little
Caulis Akebiae extracting solution carries out maturation process respectively, carries out filtering, purifying to obtain each raw material essence, mixed by each raw material essence after cooling
Close uniformly, add the Rhizoma Anemarrhenae, after dissolving, again carry out filtering, purifying, obtain mixing essence;
(3) the mixing essence, by step 2 obtained carries out homogenizing, obtain containing Ramulus Uncariae macrophyllae for cosmetics anti-dandruff in
Drug composition.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Herba Artemisiae Scopariae
The curing temperature of extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, great Ye hook
The curing temperature of rattan extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Radix Ampelopsis carries
Take the curing temperature of thing be 70-75 DEG C, pressure be 0.1-0.2Mpa, the time be 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Radix Sophorae Flavescentis carries
Take the curing temperature of liquid be 65-70 DEG C, pressure be 0.1-0.2Mpa, the time be 2-3h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Herba Clematidis Lasiandrae
The curing temperature of extracting solution is 55-60 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
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WO2003080006A1 (en) * | 2002-03-22 | 2003-10-02 | Gognis Deutschland Gmbh & Co. Kg | Use of extracts from olive trees as anti-dandruff agents |
CN1819816A (en) * | 2005-04-11 | 2006-08-16 | 孟悦华 | Chinese medicinal preparation for removing dandruff and production thereof |
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