CN103271230B - Traditional Chinese medicine feed for promoting pig growth and preparation method as well as application thereof - Google Patents

Traditional Chinese medicine feed for promoting pig growth and preparation method as well as application thereof Download PDF

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CN103271230B
CN103271230B CN201310190721.9A CN201310190721A CN103271230B CN 103271230 B CN103271230 B CN 103271230B CN 201310190721 A CN201310190721 A CN 201310190721A CN 103271230 B CN103271230 B CN 103271230B
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吕明斌
燕磊
唐婷婷
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CHENGDU CENTURY INVESTMENT Co.,Ltd.
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Shandong New Hope Liuhe Group Co Ltd
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Abstract

The invention provides a traditional Chinese medicine feed for promoting pig growth. The traditional Chinese medicine feed comprises rhizoma coptidis, white atractylodes rhizome, cyrtomium rhizome, semen pharbitidis, angelica, sweet wormwood, fructus hordei germinatus, plantain herb, pericarpium citri reticulatae viride, radix bupleuri, poria cocos, carthamus tinctorius, honeysuckle, scutellaria baicalensis, pinellia ternata, hawthorn, sculellaria barbata, rhizoma bletillae, radix sophorae flavescentis, fructus forsythiae, immature bitter orange, astragalus membranaceus, schisandra chinensis, radix scrophulariae, gastrodia elata, cortex albiziae, polygonum cuspidatum and liquorice. The adopted traditional Chinese medicine composition is reasonable in formula and can take effect synergistically. As the traditional Chinese medicine feed is used, the growth speed of a pig is accelerated obviously. In addition, the traditional Chinese medicine feed cannot generate toxic and side effects and can be used for improving the pig immunity.

Description

Somatotrophic Chinese medicine fodder and its preparation method and application for pig
Technical field
The present invention relates to field of feed, relate in particular to a somatotrophic Chinese medicine fodder and preparation method thereof for boar.
Background technology
In modernization cultivation, feed addictive is almost applied to (comprising trophism and non-nutritive additive) overall process of growth of animals or poultry.And most feed addictives all contain the compositions such as chemical drug, antibiotic and hormone, the lasting application of these compositions will cause increasing of canceration, sudden change, aberration rate.The application of feed addictive is more and more extensive, to promoting growth, the prevent disease of pig to obtain certain effect, and the level and efficiency of raising pigs improving widely, but also brought series of problems simultaneously.Because most of compound additives have all been used the medicine (as hormone, antibiotic, heavy metal etc.) of chemical synthesis class, when improving live pig output, livestock products medicine residual quantity increases, directly endangering the mankind's health, environment is also worked the mischief, cause the growing interest of Chinese scholars.Each state is all at the green additive of seeking improvement and substitute antibiotics etc.
In addition, in Pig Industry is produced, along with the expansion of scale, the raising of intensive degree, and the employing of up-to-date breeding technique, the resistance of pig becomes worse and worse, also more and more higher to the requirement of environmental condition.Various stress environment under, can cause (1) strongly or stress have harmful effect to the productivity of pig, reproductive capacity, meat and healthy etc. for a long time; (2) speed of growth of growth pig slows down or stagnates, and body weight gains declines, and the price of deed reduces, and its resistance and immunity also declines, and to some infectious diseases and the enhancing of parasitic disease neurological susceptibility, causes the popular of various epidemic diseases; For example, grice diarrhoea is a kind of typical multifactor property disease, causes that the cause of disease of grice diarrhoea is of a great variety, and characteristic of disease is complicated, can have multiple cause of disease mixed infection.Grice diarrhoea can cause price of deed rate low, and piglet survival ratio declines, and grows slowly, even stagnates (cad pig), and severe patient can be dead, to pig industry, brings huge economic loss.The control of grice diarrhoea has become a noticeable worldwide problem.The cause of disease that causes grice diarrhoea is summarized as non-infectious diarrhoea and the large class of infectious diarrhea two, treats at present grice diarrhoea, mainly adopts antibiotic and chemical synthetic drug, causes the residual height of livestock products, serious to harm.(3) reproductive capacity aspect shows as growth pig gonadal agenesis, the atrophy of Adult Pig sexual gland, sexual hypoesthesia, and semen quality declines, fetal anomaly etc.At present, in order to improve meat quality, improve the speed of growth of pig, in feed, add illegal additive event and take place frequently, to people life property safety, brought huge hidden danger.
Chinese herbal medicine majority be take natural plants as raw material, its mode of action is unique, respond well, toxic and side effect is very micro-, noresidue, without the resistance to the action of a drug, pollution-free, having the animal digestion of promotion absorbs, improve food conversion ratio and production performance, disease preventing and treating, improves animal health condition, regulates the good effects such as body non-specific immune function, and have absorb fast, drain fast advantage, thereby Chinese herbal medicine is in widespread attention with application as the research of pig additive.Modern medicine and pharmacology achievement in research shows, much Chinese medicine contains abundant polysaccharide, alkaloids, organic acid, glucoside, volatile oil and resinae etc.The Chinese medicine preparation made from these materials is for animal, have antiviral, antibacterium, anti-stress effect.Chinese medicine is with integral body adjustment, and Yin Yang balancing is feature, is comparatively ideal immunomodulator.Can improve the histiocytic activity of immune system, increase the growth of immune cell and synthesizing of antibody, regulate the immunologic function of body, improve the premunition of body, especially resist virus infections and pathogenic ability.Need now a kind of feed that effectively contains Chinese medicine, when improving immunity, effectively improve the speed of growth of pig.
Summary of the invention
Technical problem to be solved by this invention is that Chinese medicine fodder providing a kind of novel speed of growth for effective raising pig and preparation method thereof is provided, adopt this Chinese medicine fodder to there is obvious acceleration to the speed of growth of pig, have no side effect, and can also improve the raising immunity of pig simultaneously.
In order to solve the problems of the technologies described above, the invention provides the somatotrophic Chinese medicine fodder of a boar, it comprises feed vector and Chinese medicine composition additive, it is characterized in that Chinese medicine composition additive comprises: the coptis, the bighead atractylodes rhizome, rhizome of cyrtomium, kaladana, Radix Angelicae Sinensis, sweet wormwood, Fructus Hordei Germinatus, Asiatic plantain, rascal, radix bupleuri, Poria cocos, safflower, honeysuckle, the root of large-flowered skullcap, the tuber of pinellia, hawthorn, Sculellaria barbata, bletilla, kuh-seng, the capsule of weeping forsythia, the dried immature fruit of citron orange, the Radix Astragali, the fruit of Chinese magnoliavine, radix scrophulariae, rhizoma Gastrodiae, cortex albiziae, giant knotweed, Radix Glycyrrhizae.
Wherein, the ratio of weight and number of each component in described Chinese medicine composition additive is, coptis 5-10 weight portion, bighead atractylodes rhizome 10-40 weight portion, rhizome of cyrtomium 10-20 weight portion, kaladana 10-20 weight portion, Radix Angelicae Sinensis 10-30 weight portion, sweet wormwood 5-10 weight portion, Fructus Hordei Germinatus 10-50 weight portion, Asiatic plantain 10-20 weight portion, rascal 5-15 weight portion, radix bupleuri 10-25 weight portion, Poria cocos 20-30 weight portion, safflower 5-10 weight portion, honeysuckle 10-30 weight portion, root of large-flowered skullcap 10-25 weight portion, tuber of pinellia 10-15 weight portion, hawthorn 10-40 weight portion, Sculellaria barbata 10-15 weight portion, bletilla 5-10 weight portion, kuh-seng 5-10 weight portion, capsule of weeping forsythia 5-15 weight portion, dried immature fruit of citron orange 5-20 weight portion, Radix Astragali 10-30 weight portion, fruit of Chinese magnoliavine 10-15, radix scrophulariae 10-15 weight portion, rhizoma Gastrodiae 10-15 weight portion, cortex albiziae 5-10 weight portion, giant knotweed 10-15 weight portion, Radix Glycyrrhizae 10-40 weight portion.
Wherein, described Chinese medicine composition additive can will be above-mentioned Chinese medicine composition directly mix with feed after pulverizing, mix with feed vector again after also can making particular dosage form, formulation can be the regular dosage forms such as decoction, pulvis, granule, injection.
Feed vector can be one or more mixing in corn, dregs of beans, wheat bran, paddy
For solving the problems of the technologies described above, the present invention also provides the preparation method of above-mentioned feed, it comprises: the first step, each component in described Chinese medicine composition additive is mixed in proportion, obtain mixture, add the water with respect to 2 ~ 4 times of mixture qualities, decoct and process 1~3 hour, decoction liquor is filtered, concentration, obtain the lotion of removing moisture, the ethanol that is 65% ~ 75% by the determining alcohol adding in the lotion of acquisition with respect to 3~5 times of first step mixture qualities, stir 20 minutes ~ 40 minutes, at 0~4 ℃, refrigerate 1 ~ 2 hour, filter, decompression recycling ethanol, obtain and get dry extract, dry, be ground into 20 order ~ 200 object powder, obtain Chinese medicine composition additive, second step, puts into pulverizer by feed vector and is ground into 20 ~ 30 object powder, the 3rd step, the feed vector powder that the Chinese medicine composition additive that the first step is obtained, second step obtain is put into mixer and is stirred, and pours into subsequently in spraying machine, in spraying machine, water temperature is modulated at 60 ~ 70 ℃, open sprayer, stir 1 ~ 2 minute, continue to be warming up to 90 ℃ and complete expanded, the 4th step, adds the water with respect to 0.1 ~ 0.3 times of its quality by the product after expanded, puts into granulator and granulates, and granulator electric current is 175A, the 5th step, dry after granulating, baking temperature is 105 ℃, drying time 15 ~ 25min, then put into blower fan cooling, cool time, 20 ~ 40min, obtained described feed.
For solving the problems of the technologies described above, the present invention also provides the preparation method of the above-mentioned Chinese medicine composition additive of different dosage form:
The preparation method of powder: after taking raw material, bulk drug and pulverizing, sieve, fully mix and make powder.
The preparation method of granule: the first step, each component in described Chinese medicine composition additive is mixed in proportion, obtain mixture, add the water with respect to 2 ~ 4 times of mixture qualities, decoct and process 1~3 hour, decoction liquor is filtered, concentration, obtain the lotion of removing moisture, the ethanol that is 65% ~ 75% by the determining alcohol adding in the lotion of acquisition with respect to 3~5 times of first step mixture qualities, stir 20 minutes ~ 40 minutes, at 0~4 ℃, refrigerate 1 ~ 2 hour, filter, decompression recycling ethanol, obtain and get dry extract, dry, be ground into 20 order ~ 200 object powder, obtain Chinese medicine composition additive, second step, puts into pulverizer by feed vector and is ground into 20 ~ 30 object powder.
The preparation method of pulvis: each component in described Chinese medicine composition additive is mixed in proportion, obtain mixture, after crude drug mixture is pulverized, first with ethanol, medicinal material was soaked after 2 hours, alcohol reflux extracts 2 times, and each 2 hours, merging filtrate was also condensed into thick paste shape; Filter residue again water extracts 2 times, extracts for the first time 2.5 hours, extracts for the second time 1.5 hours, filters, and merging filtrate is also condensed into thick paste shape; Merge medicinal extract, finally add appropriate amount of starch and dextrin (or other auxiliary material), mix, dry, pulverize, be prepared into pulvis.
Decoction preparation method: each component in described Chinese medicine composition additive is mixed in proportion, obtain mixture, after crude drug mixture is pulverized, water soaks medicinal material after 1-2 hour, then decoct to boiling with high heat, then use slow fire boiling 30 minutes, filter, filter residue adds slow fire boiling twice for water, each 1 hour.Merging filtrate, adding ethanol to ethanol content in filtrate after filtrate is concentrated is 70%, filter, filtrate recycling ethanol, concentrated, filtration, embedding, sterilizing, be prepared into oral liquid.
Injection preparation method: each component in described Chinese medicine composition additive is mixed in proportion, obtain mixture, after crude drug mixture is pulverized, water soaks medicinal material after 1-2 hour, then with fire, decoct to boiling, then decoct 30 minutes with little fire, filter, filter residue decocts twice, each 1 hour with little fire.Merging filtrate, adding ethanol to ethanol content in filtrate after filtrate is concentrated is 70%, filter, filtrate recycling ethanol, concentrated, refrigeration, filtration, smart filter, embedding, sterilizing, be prepared into injection.
For solving the problems of the technologies described above, the present invention also provides a boar somatotrophic Chinese medicine composition, comprising: the coptis, the bighead atractylodes rhizome, rhizome of cyrtomium, kaladana, Radix Angelicae Sinensis, sweet wormwood, Fructus Hordei Germinatus, Asiatic plantain, rascal, radix bupleuri, Poria cocos, safflower, honeysuckle, the root of large-flowered skullcap, the tuber of pinellia, hawthorn, Sculellaria barbata, bletilla, kuh-seng, the capsule of weeping forsythia, the dried immature fruit of citron orange, the Radix Astragali, the fruit of Chinese magnoliavine, radix scrophulariae, rhizoma Gastrodiae, cortex albiziae, giant knotweed, Radix Glycyrrhizae.
For solving the problems of the technologies described above, the present invention also provides a boar somatotrophic Chinese medicine composition, described Chinese medicine composition is prepared from by the following method: each component in described Chinese medicine composition additive is mixed in proportion, obtain mixture, add the water with respect to 2 ~ 4 times of mixture qualities, decoct and process 1~3 hour, decoction liquor is filtered, concentration, obtain the lotion of removing moisture, the ethanol that is 65% ~ 75% by the determining alcohol adding in the lotion of acquisition with respect to 3~5 times of first step mixture qualities, stir 20 minutes ~ 40 minutes, at 0~4 ℃, refrigerate 1 ~ 2 hour, filter, decompression recycling ethanol, obtain and get dry extract, be ground into 20 order ~ 200 object powder.
For solving the problems of the technologies described above, the present invention also provides the preparation method of above-mentioned Chinese medicine composition, and it comprises:
Each component in described Chinese medicine composition additive is mixed in proportion, obtain mixture, add the water with respect to 2 ~ 4 times of mixture qualities, decoct and process 1~3 hour, decoction liquor is filtered, concentration, obtain the lotion of removing moisture, the ethanol that is 65% ~ 75% by the determining alcohol adding in the lotion of acquisition with respect to 3~5 times of first step mixture qualities, stirs 20 minutes ~ 40 minutes, refrigerates 1 ~ 2 hour at 0~4 ℃, filter, decompression recycling ethanol, obtains and gets dry extract, and is ground into 20 order ~ 200 object powder.
For solving the problems of the technologies described above, the present invention also provides above-mentioned Chinese medicine fodder and the application of Chinese medicine composition in the medicine of the growth for the preparation of promotion pig.
Beneficial effect of the present invention:
With respect to the somatotrophic Chinese medicine fodder of pig of the prior art, adopt this Chinese medicine fodder to there is obvious acceleration to the speed of growth of pig, have no side effect, and can also improve the raising immunity of pig simultaneously.
The specific embodiment
The invention provides the somatotrophic Chinese medicine fodder of such boar, it comprises feed vector and Chinese medicine composition additive, it is characterized in that Chinese medicine composition additive comprises: the coptis, the bighead atractylodes rhizome, rhizome of cyrtomium, kaladana, Radix Angelicae Sinensis, sweet wormwood, Fructus Hordei Germinatus, Asiatic plantain, rascal, radix bupleuri, Poria cocos, safflower, honeysuckle, the root of large-flowered skullcap, the tuber of pinellia, hawthorn, Sculellaria barbata, bletilla, kuh-seng, the capsule of weeping forsythia, the dried immature fruit of citron orange, the Radix Astragali:, the fruit of Chinese magnoliavine, radix scrophulariae, rhizoma Gastrodiae, cortex albiziae, giant knotweed, Radix Glycyrrhizae.
Coptis bitter, cold, nontoxic.The thoughts of returning home, spleen, stomach, liver, courage, large intestine channel.Heat-clearing and damp-drying drug, purging intense heat and detonicating.Full for damp and hot ruffian, vomiting acid regurgitation, rushes down dysentery, jaundice, and unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head is told nosebleed, hot eyes, toothache, quenches one's thirst, the carbuncle furunculosis that swells; Control eczema outward, wet sore, duct is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of prepared RHIZOMA COPTIDIS with vino is burning hot.For hot eyes, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach and stomach preventing or arresting vomiting.For fever and chills, tie mutually, damp and hot middle resistance, ruffian is completely vomitted.The easypro liver of the cornel coptis and stomach preventing or arresting vomiting.For liver-stomach disharmony, vomiting acid regurgitation.
Bighead atractylodes rhizome bitter, sweet, temperature.Return spleen, stomach warp.Cure mainly strengthening the spleen and replenishing qi, eliminating dampness Li Shui, hidroschesis, antiabortive.Few for insufficiency of the spleen food, abdominal distension is had loose bowels, and phlegm and retained fluid is dizzy throbs with fear, oedema, spontaneous perspiration, fetal irritability.< < property of medicine opinion > > carries it: monarch, taste is sweet, pungent, nontoxic.Can main large wandering arthritis, diarrhea due to disorder of qi for many years, trusted subordinate's distending pain, the broken place food that disappears, appetizing, removes sputum, except fever and chills, lets out under only.Interarea light is happy, preserves youthful looks, and de-black.The swelling of harnessing the river is full, tells to vomit contraryly, and crymodynia in abdomen, vomits and diarrhoea incessantly, and the cold dysentery of stomach Qi deficiency.Pseudo-ginseng: sweet, the micro-hardship of taste, warm in nature, enter liver, stomach warp, there is hemostasia and dissipation blood stasis, the effect of swelling and pain relieving, is mainly used in that hemoptysis, uterine bleeding etc. are various goes out blood trouble, hemangiectasis, reduces blood pressure, improve microcirculation, increase CBF, prevention and treatment heart and brain tissues ischemic, air hunger; Promote protein, ribonucleic acid (RNA), DNA (DNA) to synthesize, improve the health; Promote blood cell metabolism, balance adjustment blood cell; Bidirectional modulation nervous centralis, improves mentally, strengthens learning and memory ability; Hemostasis, promoting blood circulation and removing blood stasis; Protect the liver, anti-inflammatory.
Rhizome of cyrtomium bitter, is slightly cold.Slightly poisonous.Return liver, the spleen channel.Clearing heat and detoxicating, cooling blood and hemostasis, desinsection.Cure mainly: 1, anemopyretic cold, febrile virulent maculae.This product bitter cold, the reality heat that gas divides clearly, there is the heat poison that can separate blood system, card due to all warm malicious heresies all available it, normal and the coptis, folium isatidis, Radix Glycyrrhizae are equal to use, as rhizome of cyrtomium loose (< < Prescriptions for Universal Relief > >).Single product or join mulberry leaf, honeysuckle etc. and can prevent and treat anemopyretic cold; If with compatibilities such as Radix Isatidis, folium isatidis, Asian puccoons, can be used for again the diseases such as mumps, febrile virulent maculae, dermexanthesis.2, blood-head is hemorrhage.This product bitter is slightly cold, and main enters Liver Channel, has the merit of cooling blood and hemostasis, cures mainly bleeding from five sense organs or subcutaneous tissue due to blood-head, spits blood, has blood in stool, the disease such as uterine bleeding, the outstanding kind metrostaxis of controlling.As < < Bencao Tujing > > controls bleeding from five sense organs or subcutaneous tissue, can single grind into powder and be taken after mixing with liquid; If associate with the coptis, grind glutinous rice drink into powder and be taken after mixing with liquid, can control haematemesis, as rhizome of cyrtomium loose (< < General Records of Holy Universal Relief > >); Treating hematochezia can compatibility cacumen biotae; Controlling metrostaxis can be with excrementum pteropi with using.3, worm disease.This product has the merit of desinsection.For multiple Enterozoas such as destroying and expelling tenia, hookworm, pinworm, roundworms.Can use with anthelmintic compatibility.4, this product also can be used for treating burn and scald and married woman is with inferior disease.
Kaladana, cold in nature, bitter; Poisonous.Return lung channel, kidney channel, large intestine channel.Function cures mainly: water pouring defaecation, and drink is washed in dissolving phlegm, and desinsection is attacked long-pending.For oedema turgor, constipation and anuresis, phlegm and retained fluid is gathered, and the circulation of vital energy in the wrong direction is breathed with cough, abdominal pain due to enterositosis, roundworm, taeniasis.
Radix Angelicae Sinensis: its taste is sweet and weigh, therefore specially can enrich blood, its gas is light and pungent, thus again can promoting circulation of blood, and bowl spares has, in row, has benefit, really the gas medicine in blood, the also panacea in blood.About mending to mend of assistant, thus can support nutrition blood, tonifying Qi production of sperm, five viscera settling, body by force, beneficial mind, all tangible deficient diseases, nothing is unsuitable.Assistant logical to attack, therefore the pain defaecation of dispelling, relieving rigidity of muscles and joints, controls contraction, paralysis, the card such as dry, puckery.Seek void and exterior syndrome being not relieved person, help with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, the Biao Weire that can fall apart greatly, and table is not held back person, and assistant, with rheum officinale and so on, can be shown again admittedly.Precisely because gas Xin Erdong, thus want its quiet person when keeping away it, the sliding benefaction of property, stool is not consolidated person when keeping away it.All cloudy moderate heat Sheng persons, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable.
Sweet wormwood bitter, pungent, cold.Return liver, gallbladder channel, three warmers, kidney channel.Function with cure mainly, clear abnormal heat thoroughly, cool blood is except steaming, except steaming, preventing malaria.For summer-heat evil heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to yin labor heat, malaria fever and chills, jaundice with damp-heat pathogen.
Fructus Hordei Germinatus, taste is sweet, flat.Return spleen, stomach warp, Liver Channel.Promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn dissipate-swelling.Cure mainly dyspepsia and do not disappear, abdominal distention, insufficiency of the spleen food is few, and newborn sweat smoulders, swollen breasts, women's ablactation.
Asiatic plantain, nature and flavor: sweet; Light; Cold nature.Gui Jing: return lung channel; Liver Channel; Kidney channel; Urinary bladder channel.Function: reducing fever and causing diuresis; Excreting dampness antidiarrheal; Improving eyesight; Eliminate the phlegm.Cure mainly: main difficult urination; Under stranguria with turbid discharge band; Oedema turgor; Summer-heat and damp is rushed down dysentery; Hot eyes is hidden from view; Phlegm heat is coughed and is breathed heavily.
Rascal, bitter is pungent, warm.Enter liver, courage, stomach warp.Function, soothing the liver relieving stagnant Qi, long-pendingization that disappear are stagnant.For sternal rib gastral cavity distending pain, acute mastitis, colic, stagnation of QI due to dyspepsia.
Radix bupleuri: meridian distribution of property and flavor: cold nature, bitter, pungent, return Liver Channel, gallbladder channel, table expels the heat-evil thoroughly, soothing liver-qi stagnation, elevate a turnable ladder yang-energy, is mainly used in cold, fever, fevers and chills alternate, malaria, stagnation of QI due to depression of the liver, sternal rib pain, prolapse of the anus, uterus comes off, irregular menstruation.
Poria cocos, nature and flavor: sweet, light, flat.Gui Jing: thoughts of returning home warp, lung channel, the spleen channel, kidney channel.Function: sharp water medicine; Diuretics with the action of eliminating dampness.
Safflower is warm in nature, and taste is pungent.Cure mainly the latus rectum of invigorating blood circulation, blood stasis removing analgesic.For through closing, dysmenorrhoea, lochia, abdominal mass lump in the abdomen, traumatic injury.< < book on Chinese herbal medicine converges says > >: safflower, the medicine of broken blood, promoting circulation of blood and blood, tune blood also.Main tire produces all kinds of diseases and ailments because blood is for suffering from, or the tired bruise of blood, and coma in silence; Or lochia is robbed the heart, navel eilema; Or drop slurry is difficult raw; Or afterbirth do not fall, in the dead abdomen of son, be all just before giving birth all cards, non-safflower can not be controlled.If keeping silent, postpartum anemic fainting, mouth refer to hold in the hand; Or heresy enters blood chamber, delirious speech is gone mad; Or blood is vexed interior swollen, sudden syncope is as extremely, be all postpartum all cards, non-safflower can not be determined.All as hand over and do through closing obstructed and fever and chills, or expired stomachache and purple black dripping, or injury from falling down and the qi and blood stasis of blood is long-pending, or sore sufferings and swollenly burst uneasyly, be cards of qi and blood discord all, non-safflower can not be adjusted.< < medicineization justice > >: safflower, kind tonneau passages through which vital energy circulates, is gas medicine in blood, can rush down and can mend, and respectively has wonderful justice.If multiplex three, four money, too pungent temperature, wanders away blood.With bush, by hemostasis, close Chinese cassia tree and stimulate the menstrual flow and close, assistant is returned, Chinese herbaceous peony is controlled all over or chest abdomen pricking caused by the stagnation of QI and blood, and this its row is led and invigorates blood circulation also.
Honeysuckle: taste is sweet, cold in nature, enters the heart, lung, stomach, large intestine channel, has clearing heat and detoxicating effect, double can removing heat from the blood and relieve diarrhea.Be mainly used in affection of exogenous wind-heat, the hot poison of warm heat disease is contained, or warm disease is from the beginning of heat evil still at the part of the body cavity above the diaphragm housing the heart and lungs and when not descending; The malicious diarrhea of heat, the lower blood of stool; Heat temperature card; The sore carbuncle that hot poison gathers is from the beginning of, inflammation heat person of swelling and ache etc., honeysuckle has good antipyretic effect, energy anti-inflammatory, what control inflammation oozes out and inflammatory hyperplasia, can promote leukocytic phagocytic function, multiple pyococcus and pathogenic entero becteria are had to stronger bacteriostasis, comprise staphylococcus, hemolytic streptococcus, diplococcus meningitidis, shigella dysenteriae, typhoid bacillus, ewcastle disease, Pseudomonas aeruginosa, tubercle bacillus etc.
The root of large-flowered skullcap: bitter, cold in nature, enter the heart, lung, stomach, courage, large intestine channel, there is heat-clearing and damp-drying drug, purging intense heat and detonicating, antiabortive, the effect of hemostasis, the diarrhoea, dysentery, jaundice, the heat that are mainly used in due to damp and hot are drenched; Cough with lung heat, thirsty pharyngalgia, also can be used for fetal movement with fever, and hot malicious fire-evil is invaded the swollen card of sore carbuncle poison of excessive skin.That the root of large-flowered skullcap has is antipyretic, calm, hypotensive, diuresis, reduction capillary permeability, suppress the effects such as intestinal tube wriggling, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumopniae, typhoid bacillus, dysentery coccus, ewcastle disease, Pseudomonas aeruginosa are had to certain inhibitory action, the infection of the upper respiratory tract, chronic bronchitis, bacillary dysentery etc. are had to good curative effect.
The tuber of pinellia: function is eliminating dampness and eliminating phlegm, and stomach preventing or arresting vomiting, cure mainly the wet water drink of phlegm, and vomiting is coughed and the disease such as breathed heavily.Hawthorn, taste is sweet, slightly warm in nature is sour.Effect with cure mainly 1, hawthorn energy prevention and cure of cardiovascular disease, there is hemangiectasis, increase CF, improve heart vigor, stimulating central nervous system system, reduce blood pressure and cholesterol, softening blood vessel and diuresis and sedation; 2, crataegolic acid also has cardiotonic, also helpful to senile heart disease; 3, its energy appetite-stimulating indigestion-relieving, offsets carnivorous stagnant effect better especially, in a lot of digestant medicines, has all adopted hawthorn; 4, hawthorn has the effect activating blood circulation and dispersing blood clots, and contributes to remove local extravasated blood state, and traumatic injury is had to auxiliary curative effect; 5, hawthorn has contraction to uterus, has the effect expediting the emergence of just before giving birth time, and can promote uterine involution in postpartum pregnant woman; 6, the generation that free radical was blocked and reduced to the contained flavonoids of hawthorn and the substance such as vitamin C, carrotene, can strengthen the immunity of body, has anti-aging, anticancer effect; 7, in hawthorn, have relieving asthma reduce phlegm, the composition of anti-bacteria, treatment abdominal pain diarrhea.
The micro-hardship of Sculellaria barbata, cool.Cure mainly heat-clearing, removing toxic substances, the loose stasis of blood, hemostasis, analgesic therapy, controls haematemesis, nosebleed, blood drenches, dysentery characterized by blood in the stool, jaundice, has sore throat, lung carbuncle, furunculosis, scrofula, sore, cancerous swelling, falls the wound of forging a knife, snake bite.Modern pharmacology research shows that Sculellaria barbata has effect clearing heat and detoxicating, promoting blood circulation and removing blood stasis, antitoxin snake bite.Formula is often made Sculellaria barbata and other Chinese herbal medicines by China, and treatment hepatitis and various cancer are as cancer of the stomach, the carcinoma of the rectum, lung cancer, lymph cancer and gynecological tumor etc.
Bletilla: property is bitter, sweet, puckery, cold nature, enters lung, stomach, Liver Channel, has the effect of astringing to arrest bleeding, detumescence life, is mainly used in the hemoptysis of the deficiency syndrome of the lung, tuberculosis, yin asthenia generating intrinsic heat, the haematemesis of thermal burn stomach network; The cards such as traumatism and bleeding, bletilla has and promotes erythrocyte aggregation and local hemostatic renting, and to gastric duodenal ulcer is hemorrhage, has an anastalsis.
Kuh-seng, bitter; Cold in nature.Return liver; Kidney; Large intestine; Small intestinl channel; Bladder; The heart channel of Hang-Shaoyin; Urinary bladder channel.Effect 1, heat-clearing and damp-drying drug: extensive use and multiple humidifier fever, as damp-heat dysentery external application can be decocted soup washout, for hemorrhoid, women gynaecology.2, desinsection (external application), diuresis. function cures mainly, heat-clearing and damp-drying drug; Wind dispelling insecticide.Main damp-heat dysentery; Hematochezia; Jaundice; Difficult urination; Oedema; Under band; Pruritus vulvae; Mange; Leprosy; Pruitus; Eczema of lower limb ulcer.
The capsule of weeping forsythia is bitter, is slightly cold.Return lung, the heart, small intestinl channel.Function is clearing heat and detoxicating, dispersing swelling and dissipating binds.For ulcer, scrofula, acute mastitis, erysipelas, anemopyretic cold, warm disease is from the beginning of, warm joining the army, high hot polydipsia, coma is sent out spot, and heat is drenched renal shutdown.The medicinal part of the capsule of weeping forsythia is mainly fruit.Its shell, i.e. " sticking up " in " a kind of reed mentioned in ancient books sticks up detoxifying pills ".Contain forsythol, coumarin, oleanolic acid, saponin, citrin etc.There is the effects such as heat-clearing, removing toxic substances, dissipating bind apocenosis.Cure mainly warm, sore, scrofula, erysipelas, class's rash, influenza, with fruit, be decocted in water for oral dose, or add in prescription.Be usually used in anemopyretic cold.Nature,taste and action: Chinese medicine bitter, cold nature.Clearing heat and detoxicating, mass dissipating and swelling eliminating.Anaesthetic bitter, cool in nature." association day " clearly, antidiarrheal.Cure mainly: Chinese medicine is controlled pyreticosis from the beginning of, anemopyretic cold, heating is vexed, abscess of throat, and macula, erysipelas, scrofula, carbuncle pyogenic infections from tumour or sore, acute nephritis, heat is drenched.The anaesthetic subcutaneous ulcer of harnessing the Yellow River, intestines shouting pain, " association day " disease, intestines heat.Sheng Nong's herbal classic > >: main fever and chills, mouse impotence, scrofula, carbuncle is swollen, dislikes sore, goiter and tumor, knot heat, disease due to noxious agents produced by various parasites.
Dried immature fruit of citron orange bitter; Pungent; Cold.Return spleen; Stomach; Liver; The heart channel of Hang-Shaoyin.Effect, stops in stagnating; The full distending pain of ruffian; Constipation; After rushing down dysentery, weigh; Accumulation of pathogens in chest; Gastroptosis; The prolapse of uterus; Prolapse of the anus.
The Radix Astragali: taste is sweet, warm in nature, enter spleen, lung channel, there is help spleen soil, elevate a turnable ladder yang-energy, strengthening exterior and reducing sweat, the effects such as holder sore myogenic, are mainly used in the weak anorexia and loose stool due to spleen-lung Qi deficiency, palpitation, the visceral organ ptosis of the sinking of qi of middle-jiao, Qi dysfunction in blood control uterine bleeding is had blood in stool, and rushes down for a long time prolapse of the anus; The spontaneous sweating of exterior deficiency, the cards such as insufficiency of vital energy and blood.The Radix Astragali strengthens heart contraction ability, can improve the blood circulation of whole body, can coronary artery dilator, kidney blood vessel and adder-wort peripheral vessel, make skin blood overactive circulation; Can improve the nonspecific immunity power of body, protect the liver and fall hypoglycemic effect, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumopniae, shigella dysenteriae etc. are had to inhibitory action.The Radix Astragali can significantly affect SPL Information Conduction, realizes immunoregulation effect.
Fruit of Chinese magnoliavine temperature; Sour, sweet; Return lung, the heart, kidney channel; Restrain astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming.For the void of coughing for a long time, breathe heavily, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the feeble pulse of losing heart, interior heat is quenched one's thirst, palpitation and insomnia.< < Bencao Jingshu > > carries: the main beneficial gas person of the fruit of Chinese magnoliavine, and all gas of lung master, acid can be received, and is just entering lung tonifying lung, therefore beneficial gas is also.Its main cough with dyspnea person, the deficiency of vital energy is above stopped up and is not returned unit, and sour flavor having the property of astringing, takes the photograph gas and returns unit, and cough with dyspnea is from removing.Internal lesion caused by overexertion is won thin, tonifying for the deficiency, reinforcing yin essence, beneficial man's essence.< < does not record > > and supports the five internal organs, heat extraction, flesh person in raw the moon, the special kidney tonifying of the fruit of Chinese magnoliavine, the tonifying five zang organs of holding concurrently, kidney storing essence, essence is contained cloudy strong, receipts are taken the photograph vital qi and are returned unit, and public region is warm, digesting food, steam waste matter and change precise and tiny, smart spontaneous, essence is raw cloudy long, therefore main as above all diseases also.
Radix scrophulariae: taste is sweet, bitter, salty; Cold nature.Return lung, stomach, kidney channel, has clearing heat and cooling blood, purging intense heat and detonicating, the effect of enriching yin, is mainly used in warm heresy and joins the army, the pericardium that caves in, febrile virulent maculae, consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, Tianjin hinder that constipation, hectic fever due to yin labor are coughed, hot eyes, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Rhizoma Gastrodiae: taste is sweet, property is flat, enters Liver Channel, have calming the liver to stop the wind, spasmolysis, the effect of removing obstruction in channels to relieve pain, is mainly used in the dizziness and headache of liver-fire flaming; Convulsion due to liver-yang hyperactivity, liver wind agitation or wind phlegm are jammed, the cards such as epilepsy, also for arthralgia due to wind-dampness, articular instability, the meciless card that waits of extremity numbness, rhizoma Gastrodiae has the effect that strengthens body non-specific immune function and cellular immunity, humoral immunity.
Cortex albiziae, taste: (wooden skin) is sweet, flat, nontoxic.Gui Jing: the heart, Liver Channel.Cure mainly: lung carbuncle/traumatic injury/children's umbilical tetanus/apoplexy contracture.
Giant knotweed: mildly bitter flavor, cold nature, return liver, courage, lung channel, there is the effect of expelling wind and removing dampness, loose stasis of blood analgesic therapy, preventing phlegm from forming and stopping coughing, for joint pain, jaundice with damp-heat pathogen, through Bi , wei lump in the abdomen, coughing with a lot of sputum, scald, injury from falling down, carbuncle sore tumefacting virus.Giant knotweed has and suppresses and killing action staphylococcus aureus, staphylococcus albus, hemolytic streptococcus, micrococcus catarrhalis, ewcastle disease, proteus, Pseudomonas aeruginosa etc.
Radix Glycyrrhizae: taste is sweet, property is flat, enters 12 warps, has clearing heat and detoxicatingly, is in harmonious proportion the property of medicine, the effect of expelling phlegm and arresting coughing, and can invigorating the spleen and in, relieving spasm to stop pain, is mainly used in weakness of the spleen and the stomach abdominal distension and anorexia, weak; Can alleviate contraction pain in abdomen, relax the strong and toxicity of some drugs, alleviate medicine to the toxic and side effect of body or to GI stimulation, by adding Radix Glycyrrhizae can play tonifying Qi, neutralize, be in harmonious proportion the effect of each component.
The present invention also provides a kind of fodder compound, comprises above-mentioned Chinese medicine composition additive and feed vector in said composition.
Described feed vector is preferably one or more in corn, wheat, barley, dregs of beans.
The ratio of weight and number of described feed vector and described Chinese medicine composition additive can be 100 weight portions: 0.5~1.5 weight portion, more preferably 100 weight portions: 1~1.5 weight portion.
The present invention also provides a kind of Chinese medicine composition, comprising: the coptis, the bighead atractylodes rhizome, rhizome of cyrtomium, kaladana, Radix Angelicae Sinensis, sweet wormwood, Fructus Hordei Germinatus, Asiatic plantain, rascal, radix bupleuri, Poria cocos, safflower, honeysuckle, the root of large-flowered skullcap, the tuber of pinellia, hawthorn, Sculellaria barbata, bletilla, kuh-seng, the capsule of weeping forsythia, the dried immature fruit of citron orange, the Radix Astragali, the fruit of Chinese magnoliavine, radix scrophulariae, rhizoma Gastrodiae, cortex albiziae, giant knotweed, Radix Glycyrrhizae.
Further preferably, described pig only consists of said components with somatotrophic Chinese medicine composition.
Described pig is with in somatotrophic Chinese medicine composition, the ratio of weight and number of various components can be preferably: comprising: coptis 5-8 weight portion, bighead atractylodes rhizome 20-40 weight portion, rhizome of cyrtomium 15-20 weight portion, kaladana 10-15 weight portion, Radix Angelicae Sinensis 15-30 weight portion, sweet wormwood 6-10 weight portion, Fructus Hordei Germinatus 20-50 weight portion, Asiatic plantain 10-20 weight portion, rascal 5-10 weight portion, radix bupleuri 10-25 weight portion, Poria cocos 20-30 weight portion, safflower 5-10 weight portion, honeysuckle 15-30 weight portion, root of large-flowered skullcap 15-25 weight portion, tuber of pinellia 10-15 weight portion, hawthorn 15-40 weight portion, Sculellaria barbata 10-15 weight portion, bletilla 5-10 weight portion, kuh-seng 5-10 weight portion, capsule of weeping forsythia 5-10 weight portion, dried immature fruit of citron orange 5-10 weight portion, Radix Astragali 10-30 weight portion, fruit of Chinese magnoliavine 10-15, radix scrophulariae 12-15 weight portion, rhizoma Gastrodiae 10-15 weight portion, cortex albiziae 6-10 weight portion, giant knotweed 12-15 weight portion, Radix Glycyrrhizae 15-40 weight portion.
Described pig is with in somatotrophic Chinese medicine composition, the ratio of weight and number of various components also can be more preferably: coptis 6-8 weight portion, bighead atractylodes rhizome 20-35 weight portion, rhizome of cyrtomium 15-20 weight portion, kaladana 10-15 weight portion, Radix Angelicae Sinensis 20-25 weight portion, sweet wormwood 6-10 weight portion, Fructus Hordei Germinatus 20-30 weight portion, Asiatic plantain 15-20 weight portion, rascal 5-10 weight portion, radix bupleuri 10-25 weight portion, Poria cocos 20-25 weight portion, safflower 6-10 weight portion, honeysuckle 20-30 weight portion, root of large-flowered skullcap 15-20 weight portion, tuber of pinellia 10-15 weight portion, hawthorn 15-40 weight portion, Sculellaria barbata 10-15 weight portion, bletilla 5-10 weight portion, kuh-seng 7-10 weight portion, capsule of weeping forsythia 5-10 weight portion, dried immature fruit of citron orange 5-10 weight portion, Radix Astragali 10-30 weight portion, fruit of Chinese magnoliavine 10-15, radix scrophulariae 12-15 weight portion, rhizoma Gastrodiae 10-13 weight portion, cortex albiziae 6-8 weight portion, giant knotweed 12-14 weight portion, Radix Glycyrrhizae 15-30 weight portion.
Further preferably, described pig only consists of said components with somatotrophic Chinese medicine composition.
Described Chinese medicine composition formulation can, for decoction, powder, honey refining pill, hydration pill, tablet, capsule, oral liquid, granule, jelly or syrup, be all to adopt conventional method to be prepared from.
The administering mode of described Chinese medicine composition is oral or injection.
Below describe, in general terms the present invention, further understanding can obtain by reference to some specific embodiments, described embodiment only provides for purposes of illustration, it is restrictive being not intended.In explanation in following examples, except as otherwise noted, quantitaes is in the part by weight of umber.
The preparation of embodiment 1 Chinese medicine composition additive 1
By coptis 6g, the bighead atractylodes rhizome 20 g, rhizome of cyrtomium 15g, kaladana 10 g, Radix Angelicae Sinensis 20 g, sweet wormwood 6 g, Fructus Hordei Germinatus 20 g, Asiatic plantain 15 g, rascal 5 g, radix bupleuri 10 g, Poria cocos 20 g, safflower 6 g, honeysuckle 20 g, the root of large-flowered skullcap 15 g, the tuber of pinellia 10 g, hawthorn 15 g, Sculellaria barbata 10 g, bletilla 5 g, kuh-seng 7 g, the capsule of weeping forsythia 5 g, the dried immature fruit of citron orange 5 g, the Radix Astragali 10 g, the fruit of Chinese magnoliavine 10 g, radix scrophulariae 12 g, rhizoma Gastrodiae 10 g, cortex albiziae 6 g, giant knotweed 12 g, Radix Glycyrrhizae 15 g.Mix and pulverize; After sieving, fully mix and make powder.
The preparation of embodiment 2 Chinese medicine composition additives 2
By coptis 6g, the bighead atractylodes rhizome 20 g, rhizome of cyrtomium 15g, kaladana 10 g, Radix Angelicae Sinensis 20 g, sweet wormwood 6 g, Fructus Hordei Germinatus 20 g, Asiatic plantain 15 g, rascal 5 g, radix bupleuri 10 g, Poria cocos 20 g, safflower 6 g, honeysuckle 20 g, the root of large-flowered skullcap 15 g, the tuber of pinellia 10 g, hawthorn 15 g, Sculellaria barbata 10 g, bletilla 5 g, kuh-seng 7 g, the capsule of weeping forsythia 5 g, the dried immature fruit of citron orange 5 g, the Radix Astragali 10 g, the fruit of Chinese magnoliavine 10 g, radix scrophulariae 12 g, rhizoma Gastrodiae 10 g, cortex albiziae 6 g, giant knotweed 12 g, Radix Glycyrrhizae 15 g.Mix and pulverize; Add the water with respect to mixture quality 1500ml, decoct and process 2 hours, decoction liquor is filtered, concentration, obtains the lotion of removing moisture, the ethanol that is 65% ~ 75% by the determining alcohol that adds 2000ml in the lotion of acquisition, stir 30 minutes, at 0~4 ℃, refrigerate 1.5 hours, filter, decompression recycling ethanol, add appropriate medicinal dextrin to mix, granulate, dry, be ground into 100 object powder, granulation agent (every 1g is equivalent to crude drug in whole 2g).
The preparation of embodiment 3 Chinese medicine composition additives 3
By coptis 8g, the bighead atractylodes rhizome 35 g, rhizome of cyrtomium 20 g, kaladana 15 g, Radix Angelicae Sinensis 25 g, sweet wormwood 10 g, Fructus Hordei Germinatus 30 g, Asiatic plantain 20 g, rascal 10 g, radix bupleuri 25 g, Poria cocos 25 g, safflower 10 g, honeysuckle 30 g, the root of large-flowered skullcap 20 g, the tuber of pinellia 15 g, hawthorn 40 g, Sculellaria barbata 15 g, bletilla 10 g, kuh-seng 10 g, the capsule of weeping forsythia 10 g, the dried immature fruit of citron orange 10 g, the Radix Astragali 30 g, the fruit of Chinese magnoliavine 15, radix scrophulariae 15 g, rhizoma Gastrodiae 13 g, cortex albiziae 8 g, giant knotweed 14 g, Radix Glycyrrhizae 30 g.Mix and pulverize; After sieving, fully mix and make powder.
The preparation of embodiment 4 Chinese medicine composition additives 4
Coptis 8g, the bighead atractylodes rhizome 35 g, rhizome of cyrtomium 20 g, kaladana 15 g, Radix Angelicae Sinensis 25 g, sweet wormwood 10 g, Fructus Hordei Germinatus 30 g, Asiatic plantain 20 g, rascal 10 g, radix bupleuri 25 g, Poria cocos 25 g, safflower 10 g, honeysuckle 30 g, the root of large-flowered skullcap 20 g, the tuber of pinellia 15 g, hawthorn 40 g, Sculellaria barbata 15 g, bletilla 10 g, kuh-seng 10 g, the capsule of weeping forsythia 10 g, the dried immature fruit of citron orange 10 g, the Radix Astragali 30 g, the fruit of Chinese magnoliavine 15, radix scrophulariae 15 g, rhizoma Gastrodiae 13 g, cortex albiziae 8 g, giant knotweed 14 g, Radix Glycyrrhizae 30 g are mixed and pulverized; Add the water with respect to mixture quality 2000ml, decoct and process 2 hours, decoction liquor is filtered, concentration, obtains the lotion of removing moisture, the ethanol that is 65% ~ 75% by the determining alcohol that adds 2500ml in the lotion of acquisition, stir 30 minutes, at 0~4 ℃, refrigerate 1.5 hours, filter, decompression recycling ethanol, add appropriate medicinal dextrin to mix, granulate, dry, be ground into 100 object powder, granulation agent (every 1g is equivalent to crude drug in whole 2g).
The preparation of embodiment 5 Chinese medicine composition additives 5
Coptis 7g, the bighead atractylodes rhizome 25 g, rhizome of cyrtomium 18 g, kaladana 12 g, Radix Angelicae Sinensis 22 g, sweet wormwood 8 g, Fructus Hordei Germinatus 25 g, Asiatic plantain 18 weight portions, rascal 7 g, radix bupleuri 15 g, Poria cocos 22 g, safflower 8 g, honeysuckle 25 g, the root of large-flowered skullcap 28 g, the tuber of pinellia 12 g, hawthorn 20 g, Sculellaria barbata 12 g, bletilla 8 g, kuh-seng 8 g, the capsule of weeping forsythia 8 g, the dried immature fruit of citron orange 5 g, the Radix Astragali 20 g, the fruit of Chinese magnoliavine 12 g, radix scrophulariae 13 g, rhizoma Gastrodiae 11 g, cortex albiziae 7 g, giant knotweed 13 g, Radix Glycyrrhizae 20 g are mixed and pulverized; After sieving, fully mix and make powder.
The preparation of embodiment 6 Chinese medicine composition additives 6
Coptis 7g, the bighead atractylodes rhizome 25 g, rhizome of cyrtomium 18 g, kaladana 12 g, Radix Angelicae Sinensis 22 g, sweet wormwood 8 g, Fructus Hordei Germinatus 25 g, Asiatic plantain 18 weight portions, rascal 7 g, radix bupleuri 15 g, Poria cocos 22 g, safflower 8 g, honeysuckle 25 g, the root of large-flowered skullcap 28 g, the tuber of pinellia 12 g, hawthorn 20 g, Sculellaria barbata 12 g, bletilla 8 g, kuh-seng 8 g, the capsule of weeping forsythia 8 g, the dried immature fruit of citron orange 5 g, the Radix Astragali 20 g, the fruit of Chinese magnoliavine 12 g, radix scrophulariae 13 g, rhizoma Gastrodiae 11 g, cortex albiziae 7 g, giant knotweed 13 g, Radix Glycyrrhizae 20 g are mixed and pulverized; Add the water with respect to mixture quality 2000ml, decoct and process 2 hours, decoction liquor is filtered, concentration, obtains the lotion of removing moisture, the ethanol that is 65% ~ 75% by the determining alcohol that adds 2500ml in the lotion of acquisition, stir 30 minutes, at 0~4 ℃, refrigerate 1.5 hours, filter, decompression recycling ethanol, add appropriate medicinal dextrin to mix, granulate, dry, be ground into 100 object powder, granulation agent (every 1g is equivalent to crude drug in whole 2g).
The preparation of embodiment 7 Chinese medicine composition additives 7
Coptis 7g, the bighead atractylodes rhizome 25 g, rhizome of cyrtomium 18 g, kaladana 12 g, Radix Angelicae Sinensis 22 g, sweet wormwood 8 g, Fructus Hordei Germinatus 25 g, Asiatic plantain 18 weight portions, rascal 7 g, radix bupleuri 15 g, Poria cocos 22 g, safflower 8 g, honeysuckle 25 g, the root of large-flowered skullcap 28 g, the tuber of pinellia 12 g, hawthorn 20 g, Sculellaria barbata 12 g, bletilla 8 g, kuh-seng 8 g, the capsule of weeping forsythia 8 g, the dried immature fruit of citron orange 5 g, the Radix Astragali 20 g, the fruit of Chinese magnoliavine 12 g, radix scrophulariae 13 g, rhizoma Gastrodiae 11 g, cortex albiziae 7 g, giant knotweed 13 g, Radix Glycyrrhizae 20 g are mixed and pulverized; With 2500 water, medicinal material was soaked after 2 hours, then with fire, decoct to boiling, then decoct 30 minutes with little fire, filter, filter residue decocts twice, each 1 hour with little fire.Merging filtrate, adding ethanol to ethanol content in filtrate after filtrate is concentrated is 70%, filters, and filtrate recycling ethanol, is concentrated into every 1ml and is equivalent to crude drug in whole 1g, and refrigeration, filtration, smart filter, embedding, sterilizing, be prepared into injection.
The preparation of embodiment 8 feed vectors
6kg corn, 2kg dregs of beans, 2kg paddy are put into mixer and stir 20 minutes, pour into subsequently in pulverizer and be ground into 30 object powder, obtain feed vector.
The preparation of embodiment 9 feeds 1
Chinese medicine composition additive 5 is mixed and made with feed vector.
The preparation of embodiment 10 feeds 2
Chinese medicine composition additive 6 is mixed and made with feed vector.
Clinical trial
The toxicity test of Chinese medicine composition additive
Choose body weight and be 120 of the mouse of 18g-20g, be divided into 3 groups (female half and half), injection Chinese medicine composition adds 7 parenteral solution, three groups of dosage are determined 5g (crude drug)/kg successively, 10g (crude drug)/kg, 15g (crude drug)/kg, each dosage is all according to every mouse 0.5ml injection, the behavior performance of observed and recorded device and death condition in 7 days, and in injection latter 8 hours, 24 hours every group get respectively 5 of mouse and slaughter and cut open inspection, blood picture is carried out in blood sampling simultaneously, serum GPT detects, part mouse is carried out to histological examination, on inspection, in 7 days, respectively organize mouse and all do not occur acute poisoning symptom and death, it is active that each organizes mouse movement, gait is coordinated, smooth by hair, eyes are ruddy god, appetite, diet, ight soil is all normal, after slaughtering, cut open inspection and respectively organize Organs of Mice all without pathology, liver histological inspection is all normal, the active testing result of blood picture and serum GPT and normal mouse are without significant difference, all in normal range (NR), therefore, the security of Chinese medicine composition additive of the present invention is higher.
Test pig is DLY three way cross piglet.Select 100 of the piglets that parity, age in days are substantially close with body weight, average weight 20 kg left and right, be divided into 2 groups, be respectively Chinese medicine fodder group and antibiotic control group (interpolation flavomycoin), Chinese medicine fodder group is used feed 2, the Chinese medicine composition additive 6 that contains 1% weight, antibiotic control group add 4% flavomycoin 10g/ ton, 50 every group, male and female half and half in feed vector.Pig to be tested 20 kg left and right start test, until body weight nearly finishes during 60 kg left and right.4 groupuscules of the every circle of test pig are raised, and free choice feeding, freely drinks water, and one week preliminary trial period, feeding and management method is identical.
Mensuration project
Determination test start with finish pig individual weight, every circle feed consumption in experimental period, and within the 30th day, detect respectively the content of IgA in piglet blood, IgG, IgM and complement C3, C4 in first 1 day of the phase of just trying and test.
Immunoglobulin (Ig) and complement assay
Front and the test empty stomach in the 30th day morning respectively at test, vena cava anterior blood sampling, measure the level of serum IgA, IgG, IgM and complement C3, C4, be labeled as respectively IgA-0, IgA-30 and C3-0, C3-30 etc., adopt scattering speed turbidimetry for Determination, determining instrument is XD811 semi-automatic biochemical analyzer (upper Hisoon reaches medical apparatus corporation, Ltd and produces), and kit is that Zhejiang Province Yilikang Bioisystech Co., Ltd produces.
Statistical analysis
Test data represents with average ± standard deviation, carries out the multiple retrial proved recipe of single factor difference analysis, and all data are carried out one-way analysis of variance and minimum significantly method analysis with SPSS10.0 statistical software.
Table 1 Chinese herbal feed is the impact with feed consumption on pig weightening finish
The impact of table 2 Chinese herbal feed on pig globulin content
The impact of table 3 Chinese herb feed additive on pig complement content
Conclusion and analysis
Chinese medicine fodder group is compared with the control group of added with antibiotic, and available energy increases weight to pig, improves efficiency of feed utilization.Haematogenic immunity index determining shows, Chinese medicine fodder group is compared IgA, IgG and IgM content to be had significantly and improve with the control group of added with antibiotic, and complement C3 and C4 also have significantly and improve.IgG has antibacterial, antivirus action; IgM is combined with complement after body is subject to pathogen infection, and the effect of dissolving pathogen is very strong; Antibacterial, the antivirus action of IgA act on particularly evident in alimentary canal and respiratory tract.Complement is the chief component of specific immunity, assists antibody and phagocyte pathogenic microbe killing, undertakes the non-specific anti-infectious function of body, improves immunity.
According to other improvement and the modification of further embodiment of the present invention, according to above-mentioned instruction, be feasible.The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.Thus, will be understood that, within the scope of the appended claims, the present invention can the mode except specifically describing herein implement.

Claims (7)

1. the somatotrophic Chinese medicine fodder of a boar, it comprises feed vector and Chinese medicine composition additive, it is characterized in that Chinese medicine composition additive made by the coptis, the bighead atractylodes rhizome, rhizome of cyrtomium, kaladana, Radix Angelicae Sinensis, sweet wormwood, Fructus Hordei Germinatus, Asiatic plantain, rascal, radix bupleuri, Poria cocos, safflower, honeysuckle, the root of large-flowered skullcap, the tuber of pinellia, hawthorn, Sculellaria barbata, bletilla, kuh-seng, the capsule of weeping forsythia, the dried immature fruit of citron orange, the Radix Astragali, the fruit of Chinese magnoliavine, radix scrophulariae, rhizoma Gastrodiae, cortex albiziae, giant knotweed, Radix Glycyrrhizae;
The ratio of weight and number of each component in described Chinese medicine composition additive is, coptis 5-10 weight portion, bighead atractylodes rhizome 10-40 weight portion, rhizome of cyrtomium 10-20 weight portion, kaladana 10-20 weight portion, Radix Angelicae Sinensis 10-30 weight portion, sweet wormwood 5-10 weight portion, Fructus Hordei Germinatus 10-50 weight portion, Asiatic plantain 10-20 weight portion, rascal 5-15 weight portion, radix bupleuri 10-25 weight portion, Poria cocos 20-30 weight portion, safflower 5-10 weight portion, honeysuckle 10-30 weight portion, root of large-flowered skullcap 10-25 weight portion, tuber of pinellia 10-15 weight portion, hawthorn 10-40 weight portion, Sculellaria barbata 10-15 weight portion, bletilla 5-10 weight portion, kuh-seng 5-10 weight portion, capsule of weeping forsythia 5-15 weight portion, dried immature fruit of citron orange 5-20 weight portion, Radix Astragali 10-30 weight portion, fruit of Chinese magnoliavine 10-15 weight portion, radix scrophulariae 10-15 weight portion, rhizoma Gastrodiae 10-15 weight portion, cortex albiziae 5-10 weight portion, giant knotweed 10-15 weight portion, Radix Glycyrrhizae 10-40 weight portion.
2. the somatotrophic Chinese medicine fodder of pig as claimed in claim 1, the ratio of weight and number of each component in described Chinese medicine composition additive is, coptis 5-8 weight portion, bighead atractylodes rhizome 20-40 weight portion, rhizome of cyrtomium 15-20 weight portion, kaladana 10-15 weight portion, Radix Angelicae Sinensis 15-30 weight portion, sweet wormwood 6-10 weight portion, Fructus Hordei Germinatus 20-50 weight portion, Asiatic plantain 10-20 weight portion, rascal 5-10 weight portion, radix bupleuri 10-25 weight portion, Poria cocos 20-30 weight portion, safflower 5-10 weight portion, honeysuckle 15-30 weight portion, root of large-flowered skullcap 15-25 weight portion, tuber of pinellia 10-15 weight portion, hawthorn 15-40 weight portion, Sculellaria barbata 10-15 weight portion, bletilla 5-10 weight portion, kuh-seng 5-10 weight portion, capsule of weeping forsythia 5-10 weight portion, dried immature fruit of citron orange 5-10 weight portion, Radix Astragali 10-30 weight portion, fruit of Chinese magnoliavine 10-15 weight portion, radix scrophulariae 12-15 weight portion, rhizoma Gastrodiae 10-15 weight portion, cortex albiziae 6-10 weight portion, giant knotweed 12-15 weight portion, Radix Glycyrrhizae 15-40 weight portion.
3. the somatotrophic Chinese medicine fodder of pig as claimed in claim 1, the ratio of weight and number of each component in described Chinese medicine composition additive is, coptis 6-8 weight portion, bighead atractylodes rhizome 20-35 weight portion, rhizome of cyrtomium 15-20 weight portion, kaladana 10-15 weight portion, Radix Angelicae Sinensis 20-25 weight portion, sweet wormwood 6-10 weight portion, Fructus Hordei Germinatus 20-30 weight portion, Asiatic plantain 15-20 weight portion, rascal 5-10 weight portion, radix bupleuri 10-25 weight portion, Poria cocos 20-25 weight portion, safflower 6-10 weight portion, honeysuckle 20-30 weight portion, root of large-flowered skullcap 15-20 weight portion, tuber of pinellia 10-15 weight portion, hawthorn 15-40 weight portion, Sculellaria barbata 10-15 weight portion, bletilla 5-10 weight portion, kuh-seng 7-10 weight portion, capsule of weeping forsythia 5-10 weight portion, dried immature fruit of citron orange 5-10 weight portion, Radix Astragali 10-30 weight portion, fruit of Chinese magnoliavine 10-15 weight portion, radix scrophulariae 12-15 weight portion, rhizoma Gastrodiae 10-13 weight portion, cortex albiziae 6-8 weight portion, giant knotweed 12-14 weight portion, Radix Glycyrrhizae 15-30 weight portion.
4. the somatotrophic Chinese medicine fodder of pig as claimed in claim 1, wherein, feed vector is one or more mixing in corn, dregs of beans, wheat bran, paddy.
5. the somatotrophic Chinese medicine composition of a boar, is made by the coptis, the bighead atractylodes rhizome, rhizome of cyrtomium, kaladana, Radix Angelicae Sinensis, sweet wormwood, Fructus Hordei Germinatus, Asiatic plantain, rascal, radix bupleuri, Poria cocos, safflower, honeysuckle, the root of large-flowered skullcap, the tuber of pinellia, hawthorn, Sculellaria barbata, bletilla, kuh-seng, the capsule of weeping forsythia, the dried immature fruit of citron orange, the Radix Astragali, the fruit of Chinese magnoliavine, radix scrophulariae, rhizoma Gastrodiae, cortex albiziae, giant knotweed, Radix Glycyrrhizae;
The ratio of weight and number of each component in described Chinese medicine composition is, coptis 5-10 weight portion, bighead atractylodes rhizome 10-40 weight portion, rhizome of cyrtomium 10-20 weight portion, kaladana 10-20 weight portion, Radix Angelicae Sinensis 10-30 weight portion, sweet wormwood 5-10 weight portion, Fructus Hordei Germinatus 10-50 weight portion, Asiatic plantain 10-20 weight portion, rascal 5-15 weight portion, radix bupleuri 10-25 weight portion, Poria cocos 20-30 weight portion, safflower 5-10 weight portion, honeysuckle 10-30 weight portion, root of large-flowered skullcap 10-25 weight portion, tuber of pinellia 10-15 weight portion, hawthorn 10-40 weight portion, Sculellaria barbata 10-15 weight portion, bletilla 5-10 weight portion, kuh-seng 5-10 weight portion, capsule of weeping forsythia 5-15 weight portion, dried immature fruit of citron orange 5-20 weight portion, Radix Astragali 10-30 weight portion, fruit of Chinese magnoliavine 10-15 weight portion, radix scrophulariae 10-15 weight portion, rhizoma Gastrodiae 10-15 weight portion, cortex albiziae 5-10 weight portion, giant knotweed 10-15 weight portion, Radix Glycyrrhizae 10-40 weight portion.
6. the somatotrophic Chinese medicine composition of a boar, described Chinese medicine composition is prepared from by the following method: each component in Chinese medicine composition described in claim 5 is mixed in proportion, obtain mixture, add the water with respect to 2 ~ 4 times of mixture qualities, decoct and process 1~3 hour, decoction liquor is filtered, concentration, obtain the lotion of removing moisture, the ethanol that is 65% ~ 75% by the determining alcohol adding in the lotion of acquisition with respect to 3~5 times of first step mixture qualities, stir 20 minutes ~ 40 minutes, at 0~4 ℃, refrigerate 1 ~ 2 hour, filter, decompression recycling ethanol, obtain and get dry extract, be ground into 20 order ~ 200 object powder.
Claim 5 or 6 pig with somatotrophic Chinese medicine composition in preparation application in somatotrophic Chinese medicine fodder for pig.
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