CN102871885B - A kind of hair growth promoter and application thereof - Google Patents
A kind of hair growth promoter and application thereof Download PDFInfo
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- CN102871885B CN102871885B CN201210395803.2A CN201210395803A CN102871885B CN 102871885 B CN102871885 B CN 102871885B CN 201210395803 A CN201210395803 A CN 201210395803A CN 102871885 B CN102871885 B CN 102871885B
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Abstract
The invention discloses a kind of hair growth promoter, this hair growth promoter for essential component with humic acids sodium salt and/or potassium salt, and has blood circulation promoting and blood stasis dispelling, takes a tonic or nourishing food to build up one's health hair follicle, hair growth promoting hair care, Anti-hair loss effect; Sodium humate of the present invention (potassium) salt can blood circulation promoting, has facilitation to the hair growth of depilation mice, has certain inhibitory action to the mouse hair obscission of injection cyclophosphamide.By using sodium humate (potassium) salt as principle active component, provide have well promote hair growth, Anti-hair loss effect and natural, have no irritating odor, have no side effect, safe and reliable hair growth promoter and hair growth method.
Description
Technical field
The present invention relates to a kind of hair growth promoter, this hair growth promoter is essential component with sodium humate (potassium) salt, and have the effect promoting hair growth, Anti-hair loss, this hair growth promoter is applied in hair growth promoting, hair care, hair products (comprising medicine, health product or cosmetics) aspect.
Background technology
Humic acids (humicacid, HA) be the decomposition and inversion of animal and plant remains through microorganism, and the natural organic substance that geochemical a series of process is formed and accumulates, fulvic acid, ulmic acid and humic acid three major types can be divided into according to molecular size range, containing various active group, as carboxyl, phenolic hydroxyl group, alcoholic extract hydroxyl group, quinonyl, carbonyl etc., there is multiple biological activity.As far back as Ancient Times in China, the just existing record about similar humic acids medicine in the Compendium of Material Medica of Li Shizhen (1518-1593 A.D.), lot of experiments and clinical efficacy show that it has blood circulation promoting and blood stasis dispelling, antiinflammatory, the remarkable efficacy such as antibacterial both at home and abroad at present.
Alopecia is clinical frequently-occurring disease, commonly encountered diseases, can be judged as pathologic alopecia, mainly comprise androgenetic alopecia, alopecia areata, pseudopelade and growing period alopecia etc. when every day loses hair more than more than 100.Alopecia is for a long time the major issue of puzzlement people always, affects daily life, its cause of disease more complicated, and especially along with the increase of people's life, operating pressure, sickness rate is very high, has a strong impact on attractive in appearance.Also research and development and the sale of some product for improving hair-growing is had in the market, but some problems of ubiquity, as: (1) Chinese medicine aspect: Chinese medicine has more report to hair growth, but cannot therapy be unified; Irritant or the bad smell of some Chinese medicine self; Active ingredient of Chinese herbs mostly is organic solvent extraction, easily there is poisonous hazardous solvent and remains; Portioned product adopts the dosage form of organic solvent dissolution, even if solvent is ethanol also there is penetrating odor, even some there will be phenomena of cutaneous irritation; Raw material in some Chinese medicine product for improving hair-growing formula is too much, production technology more complicated, and product quality is difficult to control, and cost is higher; (2) Western medicine aspect: mostly be hormones or be with medicine excitatory, there is side effect, is even stopping using or after life-time service, is occurring rebound phenomenon.
Summary of the invention
According to reason and the feature of alopecia morbidity, the shortcoming for existing product and technology is not enough, the object of this invention is to provide a kind of hair growth promoting and anticreep is satisfactory for result, the hair growth promoter that has no side effect, have no irritating odor.This hair growth promoter contains humic acids sodium salt and/or humic acids potassium salt.
In the present invention, humic acids sodium salt is fulvic acid sodium and/or hymatomalenic acid sodium, and humic acids potassium salt is fulvic acid potassium and/or hymatomalenic acid potassium, is mixed by any ratio during two or more humate mixing.
In the present invention, the consumption of humic acids sodium salt and/or humic acids potassium salt is 1g/L-30g/L.
In the present invention, humic acids adopts H from peat, brown coal
20
2catalyzing oxidizing degrading legal system is standby, purification obtains, humic acids ash≤1% after purification; And yellow humic acid and hymatomalenic acid are separation and purifications from purifying humic acid, plant rotten acid except de-black and obtain; Humic acids sodium salt or potassium salt in the humic acids obtained by said method, add alkali reaction namely obtain humic acids sodium salt or potassium salt; Such as with reference to the method in application number 200810233669.X " oxidation and degradation of brown coal produces the method for humic acids and salt thereof ".
Yellow humic acid physical and chemical index: acidic groups 13.82mmol/g, carboxyl 10.18mmol/g, phenolic hydroxyl group 3.64mmol/g, the composition that molecular weight is less than or equal to 1000 is that 75%, C, H, N, O constituent content (%) is respectively 38.77,4.166,1.993,55.07.
Hair growth promoter of the present invention is from the head percutaneous hair growth promoter that to give containing one or more mixture (arbitrarily than) humic acids sodium salt and/or humic acids potassium salt be effective ingredient.
Another object of the present invention is for the preparation of hair growth promoting, hair care, hair products (comprising medicine, health product or cosmetics) using the aforementioned hair growth promoter of one or more mixture in humic acids sodium salt and/or humic acids potassium salt as effective ingredient that contain, its dosage form is lotion, emulsion, Emulsion (ointment), gel and spray etc., uses conventional method manufacture according to object dosage form.
When hair growth promoter is for the preparation of hair growth promoting, hair care, hair products, the routine used in conventional cosmetic, health product, medicine preparation process can be added as required and assist blending constituent, as being generally used for the excipient of hair growth promoter, vasodilation, wetting agent, various animals and plants activity extract, vitamins, antioxidant, water, cosolvent, metabolism revivifier, surfactant, spice and dyestuff etc., can matched combined use in the scope not affecting effect of the present invention.
Hair growth promoter of the present invention directly acts on setation position when using, and promotes that induction natural on-off cycles of hair growth is grown, hair is thickened thicker through skin.
Relative to prior art, advantage of the present invention and technique effect as follows:
1, provided by the invention with humic acids sodium salt and/or the potassium salt hair growth promoter that is main component can blood circulation promoting and blood stasis dispelling, take a tonic or nourishing food to build up one's health hair follicle, have good facilitation and Anti-hair loss effect to hair growth.
2, the humic acids as principle active component of the present invention adopts H from peat, brown coal
2o
2catalyzing oxidizing degrading legal system is standby, purification obtains, and yellow humic acid and hymatomalenic acid are separation and purifications from purifying humic acid, plants rotten acid and obtain except de-black.Yellow humic acid physical and chemical index: acidic groups 13.82mmol/g, carboxyl 10.18mmol/g, phenolic hydroxyl group 3.64mmol/g, the composition that molecular weight is less than or equal to 1000 is that 75%, C, H, N, O constituent content (%) is respectively 38.77,4.166,1.993,55.07.
3, humic acids source is polarized as peat, brown coal, the generation of some toxic and side effects of later stage can be avoided.Adopt H
2o
2catalyzing oxidizing degrading legal system is for humic acids, concise in technology, environmental protection, product biological activity are high, gained humic acids sodium salt or potassium salt is natural, self nonirritant or bad smell, do not exist poisonous hazardous solvent residual, active high, have no side effect, safe and reliable.
4, the present invention is widely applicable, all has good curative effect for alopecia in seborrheic alopecia, alopecia areata, mixed type alopecia, cancer treatment procedure etc.
Accompanying drawing explanation
Fig. 1 is mouse neonatal hair growth condition grading curve synoptic diagram of the present invention.
Fig. 2 is mice of the present invention depilation district skin heart profiles versus schematic diagram, and A is blank group; B is administration group.
Fig. 3 is mouse back skin HE stained of the present invention blank group schematic diagram;
Fig. 4 is dosage group schematic diagram in mouse back skin HE stained of the present invention;
Fig. 5 is that the present invention contains fulvic acid sodium hair growth promoter administration 0 day mice picture;
Fig. 6 is that the present invention contains fulvic acid sodium hair growth promoter administration 8 days mice pictures;
Fig. 7 is that the present invention contains fulvic acid sodium hair growth promoter administration 16 days mice pictures.
Detailed description of the invention
Below in conjunction with drawings and Examples, the present invention is described in further detail, but scope is not limited to described content.
Embodiment 1: fulvic acid sodium is to the action effect experiment of depilation mouse hair growth
The present embodiment adopts normal mouse to check fulvic acid sodium of the present invention to the action effect of depilation mouse hair growth, smears the fulvic acid sodium water preparation pharmacodynamic action of 15 days continuously observe depilation mice epilating area.
The experiment material used in the present embodiment is as follows:
(1) fulvic acid sodium: adopt brown coal H
2o
2catalyzing oxidizing degrading legal system is standby obtains fulvic acid sodium with purification, and method is with reference to the method in application number 200810233669.X " oxidation and degradation of brown coal produces the method for humic acids and salt thereof ".
(2) laboratory animal is clean type Kun Ming mice, male, body weight 18 ~ 22g, purchased from unming Medical College's Experimental Animal Center, observes two days before experiment, selects active, healthy mice for experiment.
Concrete operations are as follows: get Kunming mouse, under light anesthesia, by mass ratio 1:1 mix Colophonium and mineral wax mixture heating and melting after be applied to mouse back, until its solidify hardening after throw off gently, the epilating area area of every mice is about 2 × 2cm
2, by body weight random packet after depilation, often organize 10, totally 4 groups, specific as follows:
(1) blank group: water is smeared in depilation district;
(2) fulvic acid sodium low dosage administration group: the fulvic acid sodium water liquid smearing 1g/L;
(3) dosed administration group in fulvic acid sodium: the fulvic acid sodium water liquid smearing 5g/L;
(4) fulvic acid sodium high dose administration group: the fulvic acid sodium water liquid smearing 25g/L;
Administration every day 1 time, continuous 15 days, puts to death, surveys territory, newborn hair-fields Mus staple length and Mus gross weight, get skin of back and observe its vascularity on the 16th day.Observe each treated animal hair growth situation every day, every day, standards of grading were: be 1. grown to 0 point without hair to the virgin wool upgrowth situation scoring of mice depilation district; 2. shallow hair, growth completely lose hair or feathers district be 1 point; 3. newborn staple length and density are the do not lose hair or feathers half in district is 2 points; 4. virgin wool growth is 3 points with district's indifference of not losing hair or feathers; Scoring is carried out curve fitting, the results are shown in Table 1, Fig. 1 and Fig. 2.
Result shows: fulvic acid sodium has the effect promoting the growth of depilation mouse hair, and administration group compares with blank group significant difference, and administration mice medication area skin blood vessel obviously becomes abundanter and blood vessel is thicker.
Table 1: fulvic acid sodium on depilation mouse hair growth impact (
± s)
In table: compare with blank group, * represents P<0.05, has statistical significance, * * represents P<0.01, has significant difference.
Embodiment 2: hymatomalenic acid potassium is to the histological observation experiment of depilation mouse hair growth
This experimental example adopts normal mouse to check hymatomalenic acid potassium of the present invention to the action effect of depilation mouse hair growth, smear the hymatomalenic acid potassium water preparation pharmacodynamic action of 15 days continuously to depilation mice epilating area to observe, and paraffin section is done to newborn hair area skin, HE dyes, and carries out histological observation.
The experiment material used in the present embodiment is as follows:
(1) hymatomalenic acid potassium: adopt conventional H
2o
2oxidative degradation brown coal legal system is standby obtains hymatomalenic acid potassium with purification, and method is with reference to the method in application number 200810233669.X " oxidation and degradation of brown coal produces the method for humic acids and salt thereof ".
(2) laboratory animal is clean type Kun Ming mice, male, body weight (18 ~ 22g), purchased from unming Medical College's Experimental Animal Center, observes two days before experiment, selects active, healthy mice for experiment.
Experiment concrete operations as follows: get Kunming mouse, under light anesthesia, by mass ratio 1:1 mix Colophonium/mineral wax mixture heating and melting after be applied to mouse back, until its solidify hardening after throw off gently, the epilating area area of every mice is about 2 × 2cm
2, by body weight random packet after depilation, often organize 10, totally 4 groups, specific as follows:
(1) blank group: water is smeared in depilation district;
(2) hymatomalenic acid potassium low dosage administration group: the hymatomalenic acid potassium water liquid smearing 1g/L;
(3) dosed administration group in hymatomalenic acid potassium: the hymatomalenic acid potassium water liquid smearing 5g/L;
(4) hymatomalenic acid potassium high dose administration group: the hymatomalenic acid potassium water liquid smearing 30g/L;
Administration every day 1 time, continuous 15 days, within the 16th day, put to death, paraffin section is done to newborn hair area skin, HE dyes, carry out histological observation, hair follicle counts, the hair follicle number of every number of cases 3 high power fields (× 400), get its average, calculate again and often organize every mouse hair follicles number meansigma methods, analyze the significance of each group of difference, the results are shown in Table 2, Fig. 3 and Fig. 4.
Experimental result shows: through general histological observation, finds skin complete, without reactions such as hyperemia, edema, cell infiltration, shows that animal skin tissue is without breakage, stimulation and inflammatory reaction; Hymatomalenic acid potassium has the effect promoting mouse hair growth, and hair follicle number increases and skin corium thickness obviously thickens, and comparing with blank group has pole significant difference.
Table 2: hymatomalenic acid potassium to depilation mouse hair growing tissue learn observation experiment (
± s)
In table: compare with blank group, * represents P<0.05, has statistical significance, * * represents P<0.01, has significant difference.
Embodiment 3: fulvic acid sodium and hymatomalenic acid sodium mixture (1:5) suppress mouse hair to come off to test
The effect that this experimental example adopts the mice of intraperitoneal injection of cyclophosphamide modeling to check sodium humate of the present invention to suppress mouse hair to come off, to lumbar injection, fulvic acid sodium is smeared and hymatomalenic acid sodium mixture (1:5) the water preparation pharmacodynamic action of 28 days observes continuously in the mouse back region of cyclophosphamide, found that the mouse hair of this medicine to intraperitoneal injection of cyclophosphamide comes off and have inhibitory action, medication mice medication area skin blood vessel obviously becomes abundant, and gross weight increases.
The experiment material that the present embodiment uses is as follows:
(1) fulvic acid sodium, hymatomalenic acid sodium: adopt conventional H
2o
2oxidative degradation brown coal legal system is standby and purification is obtained, and method is with reference to the method in application number 200810233669.X " oxidation and degradation of brown coal produces the method for humic acids and salt thereof ".
(2) cyclophosphamide: Hengrui Medicine Co., Ltd., Jiangsu Prov., compound concentration is 10mg/mL, and consumption is 100mg/kg Mouse Weight.
(3) laboratory animal is clean type Kun Ming mice, male, body weight 18 ~ 22g, purchased from unming Medical College's Experimental Animal Center, observes two days before experiment, selects active, healthy mice for experiment.
Concrete operations are as follows: get Kunming mouse, by body weight random packet after intraperitoneal injection of cyclophosphamide, often organize 8, totally 4 groups, specific as follows:
(1) blank group: smear water;
(2) fulvic acid sodium and hymatomalenic acid sodium mixture (1:5) low dosage administration group: the medicinal liquid smearing 1g/L;
(3) fulvic acid sodium and the middle dosed administration group of hymatomalenic acid sodium mixture (1:5): the medicinal liquid smearing 5g/L;
(4) fulvic acid sodium and hymatomalenic acid sodium mixture (1:5) high dose administration group: the medicinal liquid smearing 25g/L;
Administration every day 1 time, continuous 28 days, puts to death, surveys coating region Mus gross weight on the 29th day, and gets skin of back and observe its vascularity situation, in table 3.
Result shows: fulvic acid sodium and hymatomalenic acid sodium mixture (1:5) have the effect promoting that mouse hair grows, the mouse hair of intraperitoneal injection of cyclophosphamide is come off and has inhibitory action, medication mice medication area skin blood vessel obviously becomes abundant, and gross weight increases.
Table 3: fulvic acid sodium and hymatomalenic acid sodium mixture on inject Acu-point plaster therapy alopecia impact (
± s)
Embodiment 4: the effect of hair growth promoter to the growth of depilation mouse hair containing fulvic acid sodium is tested
The present embodiment contains composition and the weight distribution ratio following (solvent is water) of fulvic acid sodium hair growth promoter:
Fulvic acid sodium 5g/L Radix Angelicae Sinensis 20g Radix Polygoni Multiflori 15g
Cacumen Platycladi 15g Flos Chrysanthemi Indici 10g
Preparation method: pulverize after said medicine mixing, boils after soaking 24h, cold filtration by liquid medicine than 1:4.Fulvic acid sodium is added into the liquid.
This water preparation dosage form hair growth promoter is natural, self nonirritant or bad smell, do not exist poisonous hazardous solvent remain, have no side effect, safe and reliable.The verification method adopted, with embodiment 1, take ZHANGGUANG 101 as positive control, not add fulvic acid sodium hair growth promoter for negative control, the results are shown in Table 4, Fig. 5-7.
Result shows: the hair growth promoter medication mouse skin containing fulvic acid sodium absorbs better, hair is smooth, and medication area skin blood vessel obviously becomes abundant, has the effect promoting the growth of depilation mouse hair, administration group and blank organize staple length, gross weight has significant difference, and effect is slightly better than positive control.
Table 4: containing fulvic acid sodium hair growth promoter on depilation mouse hair growth impact (
± s)
| Grouping | Staple length (cm) | Gross weight g/ (cm 2) |
| Blank | 0.61±0.08660 | 0.015±0.0040 |
| Positive control (ZHANGGUANG 101) | 0.662±0.05178 | 0.0192±0.0033 |
| Containing fulvic acid sodium hair growth promoter | 0.764±0.05029* | 0.02098±0.0023* |
| Negative control | 0.667±0.05111 | 0.0178±0.0042 |
In table: compare with blank group, * represents P<0.05, has statistical significance, * * represents P<0.01, has significant difference.
Embodiment 5: containing the hair growth promoter of fulvic acid sodium and fulvic acid potassium mixture (1:3)
The composition of hair growth promoter and weight distribution ratio following (solvent is water):
Fulvic acid sodium and fulvic acid potassium mixture (1:3) 5g/L Rhizoma Zingiberis Recens 20g
Rhizoma Pinelliae 15g Cacumen Platycladi 15g Cortex Mori 10g
Preparation method: by Rhizoma Zingiberis Recens, the Rhizoma Pinelliae, Cacumen Platycladi, Cortex Mori decocting twice, cold filtration; Add into the liquid by fulvic acid sodium and fulvic acid potassium mixture (1:3), product is water formulation.
Claims (2)
1. a hair growth promoter, is characterized in that: containing humic acids sodium salt and/or humic acids potassium salt;
The consumption of wherein said humic acids sodium salt and/or humic acids potassium salt is 1g/L-30g/L;
Described humic acids sodium salt and humic acids potassium salt obtain as follows: with peat, brown coal for raw material, adopt H
20
2catalyzing oxidizing degrading legal system is standby, purification obtains humic acids, humic acids ash≤1% after purification; Separation and purification yellow humic acid and hymatomalenic acid from the humic acids of purification; In yellow humic acid and hymatomalenic acid, add alkali reaction namely obtain humic acids sodium salt or potassium salt;
Wherein said humic acids sodium salt is fulvic acid sodium and/or hymatomalenic acid sodium;
Described humic acids potassium salt is fulvic acid potassium and/or hymatomalenic acid potassium.
2. the application of hair growth promoter described in claim 1 in preparation hair growth promoting, hair care, hair products.
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| CN104398869B (en) * | 2014-10-30 | 2017-09-29 | 昆明理工大学 | A kind of Chinese medicine compound prescription ointment for being used to treat burn and scald |
| CN106265225B (en) * | 2016-08-10 | 2019-05-31 | 云南尚呈生物科技有限公司 | A kind of eyebrow pencil composition and preparation method thereof |
| CN108078827B (en) * | 2018-01-08 | 2021-09-17 | 河北源本生物科技有限责任公司 | Alopecia-stopping and hair-growing shampoo and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1568929A (en) * | 2003-07-16 | 2005-01-26 | 刘南凯 | Cosmetics containing humic acid and application of humic acid in cosmetics |
| CN101423536A (en) * | 2008-12-02 | 2009-05-06 | 昆明理工大学 | Method for preparing humic acid and salt thereof by oxidation and degradation of brown coal |
| CN101684132A (en) * | 2008-09-25 | 2010-03-31 | 唐毅 | Production method and application of humic acid and fulvic acid extracted from humus and organic salts of mineral compounds thereof |
-
2012
- 2012-10-18 CN CN201210395803.2A patent/CN102871885B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1568929A (en) * | 2003-07-16 | 2005-01-26 | 刘南凯 | Cosmetics containing humic acid and application of humic acid in cosmetics |
| CN101684132A (en) * | 2008-09-25 | 2010-03-31 | 唐毅 | Production method and application of humic acid and fulvic acid extracted from humus and organic salts of mineral compounds thereof |
| CN101423536A (en) * | 2008-12-02 | 2009-05-06 | 昆明理工大学 | Method for preparing humic acid and salt thereof by oxidation and degradation of brown coal |
Non-Patent Citations (3)
| Title |
|---|
| 《"乌金散"助动护肤品回归大自然》;黄良才;《腐植酸》;20041231;30-31 * |
| 腐植酸医用研究新进展;周霞萍 等;《腐植酸》;20111231(第3期);5-9 * |
| 药用黄腐酸的开发应用探讨;张常书 等;《第八届全国绿色环保肥料（农药）新技术、新产品交流会》;20091224;65-69 * |
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