CN112138071A

CN112138071A - Sterilizing and inflammation-diminishing composition and preparation method and application thereof

Info

Publication number: CN112138071A
Application number: CN202011080929.1A
Authority: CN
Inventors: 宗延强; 陈惠亿; 赖明星; 王俊杰; 宗凌康
Original assignee: Guangzhou Laiyue Biotechnology Co ltd
Current assignee: Guangzhou Laiyue Biotechnology Co ltd
Priority date: 2020-10-11
Filing date: 2020-10-11
Publication date: 2020-12-29

Abstract

The application relates to the field of washing and caring, and particularly discloses a sterilization and inflammation-diminishing composition, and a preparation method and application thereof. The composition with antibacterial and anti-inflammatory effects comprises Chinese arborvitae extract, rhizoma Belamcandae extract, and fructus Trichosanthis extract; the preparation method comprises the following steps: adding Chinese arborvitae extract, rhizoma Belamcandae extract and fructus Trichosanthis extract into 60-90% ethanol solution, and stirring at 40-60 deg.C under 0.12-0.15Mpa and 80-120r/min for 20-40min to obtain composition with antibacterial and antiinflammatory effects. The sterilizing and inflammation diminishing composition can be used in washing and caring products, and has the advantages of excellent sterilizing effect and inflammation diminishing effect; in addition, the preparation method has the advantage of enabling the sterilization effect and the anti-inflammation effect of the sterilization and anti-inflammation composition to be better.

Description

Sterilizing and inflammation-diminishing composition and preparation method and application thereof

Technical Field

The application relates to the field of washing and caring products, in particular to a sterilization and inflammation-diminishing composition, a preparation method and application thereof.

Background

At present, head cleaning and protecting products, face cleaning and protecting products, body cleaning and protecting products, amphoteric cleaning and protecting products and the like are commonly used in washing and protecting products, and the existing washing and protecting products not only have good cleaning capacity, but also have the effects of sterilization and inflammation diminishing so that the skin is not easy to be infected by germs and inflammation is not easy to cause.

In order to meet the requirement of toxicological safety of washing and care products, plant extracts are usually selected as active ingredients of the bactericidal and anti-inflammatory composition, the plant extracts can bring certain bactericidal and anti-inflammatory effects, and in order to obtain better bactericidal and anti-inflammatory effects, multiple plant extracts are preferably selected for compounding.

The plant extracts comprise various substances, alkaloids, glycosides, volatile oil, unsaturated fatty acids and the like, and other unknown components, so that the mutual inhibition or the basically unchanged effect may exist in the compounding of different plant extracts, so that a few products which simultaneously meet the toxicological safety and the excellent sterilizing and anti-inflammatory effects are available on the market, the requirements of consumers are difficult to meet, and the improvement space is provided.

Disclosure of Invention

In order to satisfy toxicological safety and excellent bactericidal effect, one of the objects of the present application is to provide a bactericidal anti-inflammatory composition.

Another object of the present application is to provide a method for preparing a composition for sterilization and anti-inflammation.

The application also aims to provide application of the composition for sterilizing and diminishing inflammation.

In a first aspect, the present application provides a composition for sterilization and inflammation diminishing, which adopts the following technical scheme:

the composition with the functions of sterilization and inflammation diminishing comprises the following components in parts by mass:

3-5 parts of platycladus orientalis extract;

2-4 parts of blackberry lily extract;

3-5 parts of trichosanthes kirilowii maxim extract;

16-28 parts of 60-90% ethanol solution.

By adopting the technical scheme, the platycladus orientalis extract is added, contains quercetin and apigenin, has certain anti-inflammatory activity, mainly shows the inhibition effect of inflammatory factors, also contains myricetin, leads protein to be inactivated and lose functions through the nonspecific reaction of phenolic hydroxyl in the structure and protein in bacteria, has different degrees of sterilization effects on candida albicans, staphylococcus, streptococcus, bacillus subtilis and the like, and further has sterilization and anti-inflammatory effects.

By adding the blackberry lily extract which contains isoflavone components such as irigenin, irigenin glycoside and the like, the blackberry lily extract has anti-inflammatory effect on the early and late stages of inflammation, and has strong bacteriostatic and bactericidal effects on staphylococcus aureus, escherichia coli, pseudomonas aeruginosa and part of fungi, so that the composition has the bactericidal and anti-inflammatory effects at the same time.

The antibacterial and anti-inflammatory composition has the advantages that the trichosanthes kirilowii maxim extract is added, contains various functional components such as protein, mannose and xylose, can effectively condition the skin, provides a natural protective barrier for the skin, prevents the skin from being damaged by the outside, and has a certain effect of protecting the skin.

By adding the trichosanthes kirilowii maxim extract, the inhibition effect of the platycladus orientalis extract and the blackberry lily extract on the sterilizing and inflammation diminishing effects is relieved, and the sterilizing and inflammation diminishing effects are further enhanced, so that the sterilizing and inflammation diminishing effects of the composition are better.

Preferably, the bactericidal and anti-inflammatory composition further comprises: 3-5 parts of folium artemisiae argyi extract.

By adopting the technical scheme, the folium artemisiae argyi extract is added, so that the folium artemisiae argyi extract has an obvious bactericidal effect on staphylococcus aureus, escherichia coli, staphylococcus epidermidis and candida albicans, has the effect of reducing the secretion of inflammatory cytokines, and can inhibit the expression of IL-31 and IL-33 which cause pruritus, so that the bactericidal and anti-inflammatory composition has a better bactericidal and anti-inflammatory effect.

Preferably, the bactericidal and anti-inflammatory composition further comprises: 2.5-4.5 parts of sophora flavescens extract.

By adopting the technical scheme, the radix sophorae flavescentis extract is added, contains alkaloid and kurarinol, has good killing effect on escherichia coli, candida albicans, staphylococcus aureus and fungi, and can regulate immunity, increase leucocytes and inhibit the release of inflammation media, so that the sterilizing and inflammation diminishing effect of the composition is better.

Preferably, the bactericidal and anti-inflammatory composition further comprises: 1-3 parts of tamarind aloe extract.

By adopting the technical scheme, the aloe ferox extract is added, so that the aloe ferox extract has different degrees of inhibition effects on skin fungi such as staphylococcus aureus, escherichia coli, shigella flexneri, anaerobe, bacteroides fragilis, epidermophyton ventricosa, epidermophyton rubrum and nocardia stellata, and meanwhile, carboxypeptidase and bradypeptidase in the aloe ferox extract have obvious anti-inflammatory activity, so that the sterilization and anti-inflammation effects of the composition are better.

In a second aspect, the application provides a preparation method of a composition for sterilization and inflammation diminishing, which adopts the following technical scheme:

a preparation method of a sterilizing and inflammation diminishing composition comprises the following steps:

adding Chinese arborvitae extract, rhizoma Belamcandae extract, and fructus Trichosanthis extract into 60-90% ethanol solution, stirring at 40-60 deg.C under 0.12-0.15Mpa and 80-120r/min for 20-40min to obtain composition with antibacterial and antiinflammatory effects.

By adopting the technical scheme, the extracts can be fully fused together by pressurizing and stirring, so that a combination system is more stable, the stirring temperature is 40-60 ℃, the active ingredients of the components are not easily damaged, and the sterilizing and inflammation diminishing effects of the composition are maintained.

Preferably, the preparation method of the bactericidal and anti-inflammatory composition further comprises the following steps: mixing the Chinese arborvitae extract, the blackberry lily extract, the trichosanthes kirilowii maxim extract and 60-90% ethanol solution, adding the folium artemisiae argyi extract, and uniformly stirring to obtain the sterilizing and inflammation diminishing composition.

Preferably, the preparation method of the bactericidal and anti-inflammatory composition further comprises the following steps: mixing the Chinese arborvitae extract, rhizoma Belamcandae extract and fructus Trichosanthis extract with 60-90% ethanol solution, adding radix Sophorae Flavescentis extract, and stirring to obtain composition with antibacterial and antiinflammatory effects.

Preferably, the preparation method of the bactericidal and anti-inflammatory composition further comprises the following steps: mixing the Chinese arborvitae extract, rhizoma Belamcandae extract and fructus Trichosanthis extract with 60-90% ethanol solution, adding Aloe ferox extract, and stirring to obtain antibacterial and antiinflammatory composition.

In a third aspect, the application provides an application of a composition for sterilizing and diminishing inflammation, which adopts the following technical scheme:

the application of the bactericidal and anti-inflammatory composition comprises the step of adding the bactericidal and anti-inflammatory composition into a washing and care product.

By adopting the technical scheme, the sterilizing and inflammation diminishing composition is added into the washing and care product, so that the washing and care product has excellent sterilizing and inflammation diminishing effects.

Preferably, the addition amount of the sterilizing and inflammation diminishing composition in the washing and caring product accounts for 8% -12% of the total mass of the washing and caring product.

By adopting the technical scheme, the addition amount of the sterilizing and inflammation diminishing composition in the washing and caring product accounts for 8-12% of the total mass of the washing and caring product, so that a good sterilizing effect is achieved by using a reasonable amount, and the waste of resources is reduced.

In summary, the present application has the following beneficial effects:

1. by adding the trichosanthes kirilowii maxim extract, the inhibition effect of the platycladus orientalis extract and the blackberry lily extract on the sterilizing and inflammation diminishing effects is relieved, and the sterilizing and inflammation diminishing effects are enhanced, so that the sterilizing and inflammation diminishing effects of the composition are better.

2. The extracts can be fully fused together by pressurizing and stirring, so that a combination system is more stable, the stirring temperature is 40-60 ℃, active ingredients of the components are not easily damaged, and the sterilizing and anti-inflammatory effects of the composition are maintained.

3. By adding the sterilizing and inflammation-diminishing composition into the washing and care product, the washing and care product has excellent sterilizing and inflammation-diminishing effects.

Detailed Description

The present application will be described in further detail with reference to examples and application examples.

The source information of each raw material component in the following examples and application examples is detailed in Table 1

TABLE 1

Examples 1 to 4:

the sterilizing and inflammation diminishing composition comprises the following components:

arborvitae extract, blackberry lily extract, trichosanthes kirilowii maxim extract and 70% ethanol solution.

In examples 1 to 4, the amounts (parts) of the respective components added are specified in Table 2

TABLE 2

	Example 1	Example 2	Example 3	Example 4
					Platycladus orientalis extract	3	4	4.5	5
Rhizoma Belamcandae extract	2	3	3.5	4
					Trichosanthes kirilowii Maxim extract	3	4	4.5	5
70% ethanol solution	16	22	25	28

The preparation method of the anti-aging day cream of examples 1 to 4 includes the following steps:

adding Chinese arborvitae extract, rhizoma Belamcandae extract, fructus Trichosanthis extract, and 70% ethanol solution into a stirring kettle, and stirring at 50 deg.C under 0.13Mpa and 100r/min for 30min to obtain the composition with antibacterial and antiinflammatory effects.

Example 5

Compared with example 2, the difference is only that: in the step, the pressure is 0.12Mpa, the temperature is 40 ℃, the rotating speed is 80r/min, and 60 percent ethanol solution is used.

Example 6

Compared with example 2, the difference is only that: in the step, the pressure is 0.15Mpa, the temperature is 60 ℃, the rotating speed is 120r/min, and 90 percent ethanol solution is adopted.

Examples 7 to 10

Compared with example 2, the difference is only that:

the composition for sterilizing and diminishing inflammation also comprises folium Artemisiae Argyi extract.

In examples 7 to 10, the amounts (parts) of the respective components added are specified in Table 3

TABLE 3

	Example 7	Example 8	Example 9	Example 10
					Platycladus orientalis extract	4	4	4	4
Rhizoma Belamcandae extract	3	3	3	3
					Trichosanthes kirilowii Maxim extract	4	4	4	4
70% ethanol solution	16	22	25	28
					Folium Artemisiae Argyi extract	3	4	4.5	5

Adding folium Artemisiae Argyi extract, Chinese arborvitae extract, rhizoma Belamcandae extract, fructus Trichosanthis extract, and 70% ethanol solution into a stirring kettle, and stirring.

Examples 11 to 14

Compared with example 2, the difference is only that:

the composition for sterilizing and diminishing inflammation also comprises a lightyellow sophora root extract.

In examples 11 to 14, the amounts (in Kg) of the respective components added are specified in Table 4

TABLE 4

Adding radix Sophorae Flavescentis extract, Chinese arborvitae extract, rhizoma Belamcandae extract, fructus Trichosanthis extract, and 70% ethanol solution into stirring kettle, and stirring.

Examples 15 to 18

Compared with example 2, the difference is only that:

the composition for sterilizing and relieving inflammation further comprises Aloe ferox extract.

In examples 15 to 18, the amounts (in Kg) of the components added are specified in Table 5

TABLE 5

Adding the Aloe ferox Miller extract, Chinese arborvitae extract, rhizoma Belamcandae extract, fructus Trichosanthis extract, and 70% ethanol solution into a stirring kettle, and stirring.

Examples 19 to 22

Compared with example 2, the difference is only that:

the composition also comprises folium Artemisiae Argyi extract, radix Sophorae Flavescentis extract, and Aloe ferox extract.

In examples 19 to 22, the amounts (in Kg) of the respective components added are specified in Table 6

TABLE 6

Adding folium Artemisiae Argyi extract, radix Sophorae Flavescentis extract, Aloe ferox extract, Chinese arborvitae extract, rhizoma Belamcandae extract, fructus Trichosanthis extract, and 70% ethanol solution into a stirring kettle, and stirring.

Comparative example 1

Compared with example 2, the difference is only that:

in the step of preparing the sterilizing and inflammation diminishing composition, 70% ethanol solution is used to replace the equal amount of the platycladus orientalis extract, the blackberry lily extract and the trichosanthes kirilowii maxim extract.

Comparative example 2

Compared with example 2, the difference is only that:

in the step of preparing the sterilizing and inflammation diminishing composition, 70 percent ethanol solution is adopted to replace the blackberrylily rhizome extract and the trichosanthes kirilowii maxim extract in equal amount.

Comparative example 3

Compared with example 2, the difference is only that:

in the step of preparing the sterilizing and inflammation diminishing composition, 70% ethanol solution is used to replace the extract of Chinese arborvitae and the extract of Chinese trichosanthes in equal amount.

Comparative example 4

Compared with example 2, the difference is only that:

in the step of preparing the sterilizing and inflammation diminishing composition, 70% ethanol solution is used to replace the arborvitae extract and the blackberry lily extract in equal amount.

Comparative example 5

Compared with example 2, the difference is only that:

Comparative example 6

Compared with example 2, the difference is only that:

Comparative example 7

Compared with example 2, the difference is only that:

Comparative example 8

Comparative example 8 of the present application discloses a shampoo:

the shampoo comprises the following components in parts by mass:

42.7Kg of ammonium lauryl sulfate, 14.2Kg of dimethyl silicone oil, 14.2Kg of potassium alginate, 20Kg of sucrose cottonseed oleate, 4725.7Kg of polyquaternium, 14.2Kg of hyaluronic acid, 5.7Kg of citric acid, 17.2Kg of octyl dodecanol, 8.5Kg of sodium polyglutamate, 0.3Kg of methylisothiazolinone and 88.3Kg of deionized water.

The preparation method of the shampoo comprises the following steps:

step 1), adding lauryl alcohol ether ammonium sulfate, dimethyl silicone oil, sucrose cottonseed oleate, polyquaternium-47, methylisothiazolinone, octyl dodecanol and deionized water into an emulsification homogenizer, heating to 80 ℃ while stirring, rotating at the speed of 100r/min, stirring for 30min, and homogenizing for 20min to obtain a premix;

and 2), cooling the premix to 50 ℃, adding potassium alginate, hyaluronic acid, citric acid and sodium polyglutamate into an emulsifying homogenizer at the rotating speed of 80r/min, and stirring for 20min to obtain the shampoo.

Comparative example 9

Comparative example 9 of the present application discloses a hand sanitizer:

the hand sanitizer comprises the following components in parts by mass:

0.8Kg of carbomer gel, 0.2Kg of chlorhexidine gluconate, 0.2Kg of triclosan, 7.7Kg of glycerol, 6.7Kg of propylene glycol, 4.8Kg of stearic acid, 4.8Kg of polyethylene glycol-4007.7 Kg, 0.2Kg of lavender essential oil, 53.8Kg of vitamin B, 3.8Kg of tocopheryl ester, 11.5Kg of glyceryl stearate, 8.1Kg of coconut monoethanolamide, 6.3Kg of diazolidinyl urea, 9.6Kg of natural olive oil, 6.0Kg of triethanolamine and 173.1Kg of deionized water.

The preparation method of the hand sanitizer comprises the following steps:

step 1), adding deionized water, carbomer gel, stearic acid, propylene glycol, glycerol, polyethylene glycol and glycerol stearate into a stirring kettle, heating to 85 ℃ while stirring, and stirring for 25min at a rotating speed of 100r/min to obtain a premix;

and 2) cooling the premix to 60 ℃, adding triclosan, triethanolamine, chlorhexidine gluconate, vitamin B5, tocopheryl acid ester, lavender essential oil, coconut monoethanolamide, diazolidinyl urea and natural olive oil into a stirring kettle, stirring at the rotating speed of 80r/min for 20min, and thus obtaining the hand sanitizer.

Comparative example 10

Comparative example 10 of the present application discloses a private care solution:

the private care solution comprises the following components in parts by mass:

1.9Kg of lactic acid bacteria, 8.3Kg of lactic acid, 44.0Kg of sodium methyl cocoyl taurate, 39.3Kg of butanediol, 3.1Kg of sea buckthorn seed oil, 0.7Kg of p-hydroxybenzoic acid and 154.8Kg of deionized water.

The preparation method of the private care solution comprises the following steps:

step 1), adding sodium methyl cocoyl taurate, sea buckthorn seed oil and deionized water into a stirrer, heating to 85 ℃ while stirring, rotating at a speed of 80r/min, and stirring for 20min to obtain a first mixture;

step 2), cooling the first mixture to 60 ℃, adding the sterilizing and anti-inflammatory composition, the lactic acid bacteria, the butanediol and the p-hydroxybenzoic acid into a stirrer, rotating at the speed of 100r/min, and stirring for 30min to obtain a second mixture;

and 3) adding lactic acid into the stirrer, stirring for 10min, and adjusting the pH to 4.5 to obtain the private care solution.

Comparative example 11

Comparative example 11 of the present application discloses a shower cream:

the shower cream comprises the following components in parts by mass:

26.6Kg of ethoxylated alkyl sodium sulfate, 22.6Kg of starch sugar octenyl succinate, 1.1Kg of cetyltrimethylammonium bromide, 4.0Kg of vitamin E, 9.3Kg of glycerol, 2.1Kg of citric acid, 2.1Kg of triethanolamine, 9.6Kg of transparent xanthan gum, 1.1Kg of phenoxyethanol, 1.1Kg of essence and 172.9Kg of deionized water.

The preparation method of the shower cream comprises the following steps:

step 1), adding deionized water, ethoxylated alkyl sodium sulfate, octenyl succinic acid starch sugar ester and transparent xanthan gum into a stirring kettle, heating to 80 ℃ while stirring, rotating speed of 80r/min, and stirring for 40min to obtain a premix;

and 2) cooling the premix to 65 ℃, adding citric acid, triethanolamine, cetyltrimethylammonium bromide, phenoxyethanol, vitamin E, glycerol, essence and the sterilizing and anti-inflammatory composition into a stirring kettle, and stirring at the rotating speed of 35r/min for 20min to obtain the body wash.

Experimental examples 1 to 29

Experimental examples 1 to 29 of the present application disclose a shampoo:

in the experimental examples 1 to 29, shampoos prepared by adding the bactericidal and anti-inflammatory compositions prepared in examples 1 to 22 and comparative examples 1 to 7, respectively, to comparative example 8 were prepared.

Experimental examples 30 to 58

Experimental examples 30 to 58 of the present application disclose a liquid soap:

in the experimental examples 30 to 58, the hand washing solutions prepared by adding the compositions for sterilizing and diminishing inflammation prepared in the examples 1 to 22 and the comparative examples 1 to 7 respectively to the comparative example 9 were used.

Application examples 1 to 3

Experimental examples 1-3 of the present application disclose a personal care solution:

in experimental examples 1 to 3, the personal care solutions prepared by adding the bactericidal and anti-inflammatory compositions prepared in example 2, example 20 and comparative example 1 to comparative example 10, respectively, were used.

Application examples 4 to 6

Experimental examples 4 to 6 of the present application disclose a body wash:

in the experimental examples 4 to 6, the bath milks prepared by adding the bactericidal and anti-inflammatory compositions prepared in example 2, example 20 and comparative example 1 to comparative example 11, respectively, were used.

Experiment 1

Sterilization performance detection

Taking freeze-dried strain tubes of staphylococcus aureus, candida albicans, escherichia coli and propionibacterium acnes, adding a proper amount of nutrient broth into a capillary suction tube, culturing in 10ml of culture medium at 37 ℃ for 18h, then inoculating the nutrient broth onto a nutrient agar slant, transferring the lotion into another sterile tube by using the suction tube, shaking and knocking 80 times on a palm to ensure that the bacterial suspension is uniform, and the bacterial content is 1 multiplied by 10⁸-3×10⁸cfu/ml, using sterile forceps to clamp one corner of sterilized 10mm × 10mm filter paper, injecting 10 μ l bacterial suspension, placing into sterile plate, drying in 37 deg.C oven for 20min, making into bacterial tablet, diluting 5g of the washing product in each application example to 0.02g/ml, sucking 5.0ml of sample liquid, injecting into a sterilized plate, after 12 hours of action, 5.0ml of neutralizing agent is added and mixed evenly, after 10 minutes of neutralization, 15ml of nutrient agar culture medium at 40 ℃ is inoculated, the mixture is rotated under a plate 15, after solidification, the mixture is cultured at 35 +/-2 ℃ for 48 hours, viable bacteria colonies are counted, three groups of experiments are carried out, the average value is taken, the final result is that the sterilization rate (%) - (A-B)/A multiplied by 100 percent, A is the average colony number of the cleaning and protecting product added with the composition of the comparative example 1 in the application example, and B is the average colony number of the cleaning and protecting product added with the composition of the comparative examples 2-7 in the application example.

Experiment 2

Detection of anti-inflammatory Properties

72 female Balb/c mice with a body mass of 14-18g were prepared, given sufficient food and water, adaptively feeding at 25 + -2 deg.C and humidity of 60 + -5% for 24h, then randomly dividing mice into 36 groups of 2 mice each, marking a detection area inside and outside the right ear of the mouse, uniformly coating 20ml/ear of dimethylbenzene on the marking area for causing inflammation, measuring the ear thickness X of the mouse in the marking area after 30imn, uniformly coating 0.6 +/-0.02 mg/ear of the washing and caring products prepared by each application example on a marked area, cleaning after 5min, the above procedure was repeated every 2h for 6h, the mouse ear thickness Y of the marked region after 6h was measured, the net reduction in the mouse ear thickness was calculated, and the anti-inflammatory rate (%) - (X-Y)/X × 100% was calculated, and the final anti-inflammatory effect was expressed as the average of the anti-inflammatory rates.

The detailed data of experiment 1 and experiment 2 are shown in Table 7

TABLE 7

According to comparison of data in experimental example 24 and experimental example 23, and data in experimental example 53 and experimental example 52 in table 7, the disinfection rate and the anti-inflammatory rate are improved by adding the biota orientalis extract, which indicates that the biota orientalis extract has the disinfection and anti-inflammatory effects, so that the washing and care product has the disinfection and anti-inflammatory effects.

According to the comparison between the data of experimental example 25 and experimental example 23, and the data of experimental example 54 and experimental example 52 in table 7, the sterilization rate and the anti-inflammatory rate are improved by adding the belamcanda chinensis extract, which indicates that the belamcanda chinensis extract has the sterilization and anti-inflammatory effects, so that the washing and caring product has the sterilization and anti-inflammatory effects.

According to comparison of data of experimental example 26 and experimental example 23, and data of experimental example 55 and experimental example 52 in table 7, the bactericidal rate and the anti-inflammatory rate are not obviously changed by adding the trichosanthes kirilowii maxim extract, which indicates that the trichosanthes kirilowii maxim extract has the bactericidal and anti-inflammatory effects without negative influence.

According to comparison of data in experimental example 27, experimental examples 24 and 25, and experimental example 56, experimental examples 53 and 54 in table 7, the addition of the arborvitae extract and the blackberry lily extract has a bactericidal rate higher than that of the arborvitae extract alone and lower than that of the blackberry lily extract alone, which indicates that the arborvitae extract has an inhibitory effect on the bactericidal effect of the blackberry lily extract, and the anti-inflammatory rate is higher than that of the blackberry lily extract alone and lower than that of the blackberry lily extract alone, which indicates that the blackberry lily extract has an inhibitory effect on the anti-inflammatory effect of the arborvitae extract.

According to comparison of data of experimental example 27 and experimental example 2 in table 7 and data of experimental example 56 and experimental example 31, the bactericidal rate and the anti-inflammatory rate are greatly increased by adding the trichosanthes kirilowii maxim extract, which indicates that the trichosanthes kirilowii maxim extract relieves the inhibition effect of the platycladus orientalis extract on the bactericidal effect of the belongings, relieves the inhibition effect of the platycladus orientalis extract on the bactericidal effect, improves the bactericidal rate and the anti-inflammatory rate, and enables the bactericidal and anti-inflammatory composition to have better bactericidal and anti-inflammatory effects in washing and protecting products.

According to the comparison between the data of experimental example 8 and experimental example 2 in table 7 and the data of experimental example 37 and experimental example 31, the sterilization rate and the anti-inflammatory rate of the added folium artemisiae argyi extract are both improved, which indicates that the folium artemisiae argyi extract has certain sterilization and anti-inflammatory effects, so that the sterilization and anti-inflammatory effects of the washing and caring product are better.

According to comparison of data of experimental example 12 and experimental example 2, and data of experimental example 41 and experimental example 31 in table 7, the bactericidal rate and the anti-inflammatory rate are both improved by adding the sophora flavescens extract, which indicates that the sophora flavescens extract has certain bactericidal and anti-inflammatory effects, so that the bactericidal and anti-inflammatory effects of the washing and caring product are better.

According to comparison of data of experimental example 16 and experimental example 2, and data of experimental example 45 and experimental example 31 in table 7, the sterilization rate and the anti-inflammatory rate of the aloe ferox extract are improved, which indicates that the aloe ferox extract has certain sterilization and anti-inflammatory effects, so that the sterilization and anti-inflammatory effects of the washing and caring product are better.

According to the comparison of the data of the experimental example 20 and the experimental examples 8, 12 and 16 in the table 7 and the data of the experimental example 49 and the experimental examples 37, 41 and 45, the sterilization rate and the anti-inflammatory rate are improved by adding the artemisia leaf extract, the sophora flavescens extract and the aloe ferox extract, which shows that the artemisia leaf extract, the sophora flavescens extract, the aloe ferox extract and the sterilization and anti-inflammatory composition play a synergistic effect in the sterilization and anti-inflammatory effects, so that the sterilization and anti-inflammatory effects of the washing and care product are better.

According to the comparison between the data of the application example 3 and the data of the comparative example 10 and the data of the application example 16 and the data of the comparative example 11 in the table 7, the sterilization rate and the anti-inflammatory rate are basically unchanged, and the fact that the sterilization and anti-inflammatory effects in the private care solution are not negatively influenced by adding the deionized water is shown.

According to the comparison between the data of the application example 1 and the data of the application example 3 and the data of the application example 4 and the data of the comparative example 6 in the table 7, the sterilization rate and the anti-inflammatory rate are both improved, which shows that the sterilization and anti-inflammatory effect of the sterilization and anti-inflammatory composition in the private care solution is improved, so that the sterilization and anti-inflammatory effect of the private care solution is better.

According to the comparison of the data of the application example 2 and the application example 3 in the table 7 and the comparison of the data of the application example 5 and the comparison example 6, the sterilization rate and the anti-inflammatory rate are both improved, which indicates that the sterilization and anti-inflammatory composition added with the sophora flavescens extract, the artemisia argyi extract and the aloe ferox extract has the advantages of improving the sterilization and anti-inflammatory effects in the private care solution and enabling the sterilization and anti-inflammatory effects of the private care solution to be better.

According to the comparison between the data of the application example 3 and the data of the comparative example 10 and the data of the application example 16 and the data of the comparative example 11 in the table 7, the sterilization rate and the anti-inflammatory rate are basically unchanged, and the fact that the sterilization and anti-inflammatory effects of the shower cream are not negatively influenced by adding the deionized water is shown.

According to the comparison of the data of the application examples 1 and 3 and the data of the application examples 4 and 6 in the table 7, the sterilization rate and the anti-inflammation rate are improved, which shows that the sterilization and anti-inflammation effect of the sterilization and anti-inflammation composition in the bath milk is improved, so that the sterilization and anti-inflammation effect of the bath milk is better.

According to the comparison of the data of the application example 2 and the application example 3 in the table 7 and the comparison of the data of the application example 5 and the comparison example 6, the sterilization rate and the anti-inflammatory rate are both improved, which shows that the sterilization and anti-inflammatory composition added with the sophora flavescens extract, the artemisia argyi extract and the aloe ferox extract has the advantages of improving the sterilization and anti-inflammatory effects and enabling the sterilization and anti-inflammatory effects of the bath lotion to be better.

The present embodiment is only for explaining the present application, and it is not limited to the present application, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present application.

Claims

1. The sterilizing and inflammation diminishing composition is characterized in that: the paint comprises the following components in parts by mass:

3-5 parts of platycladus orientalis extract;

2-4 parts of blackberry lily extract;

3-5 parts of trichosanthes kirilowii maxim extract;

16-28 parts of 60-90% ethanol solution.

2. The bactericidal and anti-inflammatory composition of claim 1, wherein: the paint also comprises the following components in parts by mass:

3-5 parts of folium artemisiae argyi extract.

3. The bactericidal and anti-inflammatory composition of claim 1, wherein: the paint also comprises the following components in parts by mass:

2.5-4.5 parts of sophora flavescens extract.

4. The bactericidal and anti-inflammatory composition of claim 1, wherein: the paint also comprises the following components in parts by mass:

1-3 parts of tamarind aloe extract.

5. The method for preparing the composition for sterilizing and diminishing inflammation according to claim 1, wherein the composition comprises the following components in percentage by weight:

adding Chinese arborvitae extract, rhizoma Belamcandae extract and fructus Trichosanthis extract into 60-90% ethanol solution, stirring at 40-60 deg.C under 0.12-0.15Mpa and 80-120r/min for 20-40min to obtain composition with antibacterial and antiinflammatory effects.

6. The method for preparing the composition for sterilizing and diminishing inflammation according to claim 5, wherein the composition comprises the following components in percentage by weight: mixing the Chinese arborvitae extract, the blackberry lily extract, the trichosanthes kirilowii maxim extract and 60-90% ethanol solution, adding the folium artemisiae argyi extract, and uniformly stirring to obtain the sterilizing and inflammation diminishing composition.

7. The method for preparing the composition for sterilizing and diminishing inflammation according to claim 5, wherein the composition comprises the following components in percentage by weight: mixing the Chinese arborvitae extract, rhizoma Belamcandae extract, fructus Trichosanthis extract and 60-90% ethanol solution, adding radix Sophorae Flavescentis extract, and stirring to obtain antibacterial and antiinflammatory composition.

8. The method for preparing a bactericidal and anti-inflammatory composition as claimed in claim 5, wherein the arborvitae extract, blackberry lily extract, trichosanthes kirilowii maxim extract and 60-90% ethanol solution are mixed, and aloe ferox extract is further added, and the mixture is stirred uniformly to obtain the bactericidal and anti-inflammatory composition.

9. The use of a bactericidal and anti-inflammatory composition as claimed in claim 1, wherein: the sterilizing and inflammation diminishing composition is added into a washing and caring product.

10. The use of a bactericidal and anti-inflammatory composition as claimed in claim 9, wherein: the addition amount of the sterilizing and inflammation diminishing composition in the washing and protecting product accounts for 8-12% of the total mass of the washing and protecting product.