CN105326681B - A kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract and preparation method thereof - Google Patents
A kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Abstract
The invention belongs to field of daily chemicals, and in particular to a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract and preparation method thereof.The anti-bacterial hand lotion containing Folium Artemisiae Argyi extract of the present invention is mainly made up of aliphatic acid sodium isethionate, SAS, Dodecyl Glucoside, NMF, plant extracts, tetrasodium ethylenediamine tetraacetate, sodium chloride, citric acid, jojoba oil and water.Anti-bacterial hand lotion provided by the invention containing Folium Artemisiae Argyi extract have foam it is soft and smooth it is fine and smooth, non-stimulated, do not hurt hands, and dirt-removing power by force and antibacterial action it is notable the advantages of, can reach fast and effectively cleaning both hands effect.The hand cleanser also added NMF and jojoba oil simultaneously, there is moist, moisturizing after use to skin, can effectively prevent that the phenomenon dried, peeled occurs in skin after using hand cleanser.
Description
Technical field
The invention belongs to field of daily chemicals, and in particular to a kind of anti-bacterial hand lotion and its system containing Folium Artemisiae Argyi extract
Preparation Method.
Background technology
Modern study finds that many pathogen of people are all internal by entering in hand feed mouth, or by hand and nose,
The location contacts such as eye are taken advantage of a weak point.Therefore, people increasingly focus on the health of hand.Past, people use perfumed soap conduct always
Hand-washing article, but due to perfumed soap, easily landing, chance water and high temperature can soften and consume naturally when in use, and easily become bacterium
Pollution sources and gradually substituted by other hand-washing articles.At present, in order to avoid the secondary pollution that hand-washing article is brought, antibacterial type are washed
Hand liquid turns into main flow.
At present, anti-bacterial hand lotion on the market is mainly to sterilize antibacterial effect by adding chemical raw material to reach it,
But long-term use of this hand cleanser can cause larger stimulation to skin, easily there is dry skin, coarse and chap phenomenon,
If also cleaning in use not thoroughly, chemical raw material can be passed to intraoral by hand, and larger harm is produced to human body.
Plant extracts contains substantial amounts of fungicide active ingredient, and is a kind of bactericide not hurt hands naturally to no skin irritation.
Therefore, it is more and more favored by consumers as the hand cleanser of bactericide to add plant extracts.
Chinese patent CN101185621B discloses a kind of Chinese herbal medicinal antibacterial hand cleanser and preparation method thereof, and the antibacterial is washed
Hand liquid is by 50% alkyl-glucoside, AEO (9), AEO (7), 30% dodecane
Base dimethyl betaine, 70% sodium sulfate of polyethenoxy ether of fatty alcohol, 5% moutan bark extract, 5% radix glycyrrhizae extract, 5% mountain
Tea fruit extract, essence, citric acid and deionized water composition.The Chinese herbal medicinal antibacterial hand cleanser being prepared has relatively strong sterilization effect
Fruit, but also there is decontamination, moist, moisturizing and handguard.But the AEO (9) in the hand cleanser
It is a kind of low toxicity material with AEO (7), in long-term suction body, larger injury is produced to health.
Chinese patent CN102949310B discloses a kind of Chinese medicine antibacterial hand cleanser and preparation method thereof, the Chinese medicine antibacterial
Hand cleanser by hydroxyethyl cellulose, Dodecyl Polyoxyethylene Ether sodium sulphate, lauryl sodium sulfate, coconut oleoyl diethanol amine,
KF88 CG, natural borneol, citric acid, sodium benzoate, essence, natural pigment, climbing groundsel and Rosmarinus officinalis extract and deionized water
Composition.The Chinese medicine antibacterial hand cleanser being prepared has the function that preferable decontamination, antibiotic and sterilizing and skin care.But should
Lauryl sodium sulfate and coconut oleoyl diethanol amine in anti-bacterial hand lotion is irritant to skin and eyes, is unfavorable for long-term
Use.
The content of the invention
The defects of existing for the hand cleanser for solving prior art, it is an object of the invention to provide it is a kind of it is safe,
Antibiotic and sterilizing effect is good, it is non-stimulated, do not hurt hands, and the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract with certain skin care effect and
Its preparation method, to solve disadvantages described above.
The invention provides a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract, including following components and its parts by weight：
Aliphatic acid sodium isethionate 8-12 parts, SAS 6-10 parts, Dodecyl Glucoside 7-15 parts, NMF
1-4 parts, plant extracts 1-3 parts, tetrasodium ethylenediamine tetraacetate 0.1-1 parts, sodium chloride 0.02-0.5 parts, citric acid 0.1-1 parts,
Jojoba oil 0.02-0.08 parts and water 70-90 parts.
Further, the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract includes following components and its parts by weight：
10 parts of aliphatic acid sodium isethionate, 7 parts of SAS, 12 parts of Dodecyl Glucoside, 2 parts of NMF, plant
2 parts of thing extract, 0.5 part of tetrasodium ethylenediamine tetraacetate, 0.2 part of sodium chloride, 0.4 part of citric acid, 0.04 part of jojoba oil and water
80 parts.
Further, the NMF is by sodium lactate and glycerine 1-2 by volume:1-3 is formed.
Further, the NMF is by sodium lactate and glycerine by volume 1:2 compositions.
Further, the plant extracts by Folium Artemisiae Argyi extract, Lonicera confusa extract and Herba Plantaginis extract by weight
Compare 2-4:0.5-2:1-2 is formed.
Further, the plant extracts by Folium Artemisiae Argyi extract, Lonicera confusa extract and Herba Plantaginis extract by weight
Than 3:1:1.5 composition.
Aliphatic acid sodium isethionate in anti-bacterial hand lotion provided by the invention containing Folium Artemisiae Argyi extract be it is a kind of by
The green anion surfactant for the purified fatty acid production extracted from natural coconut oil, it has excellent detergency
Energy, stability in hard water energy, skin-friendliness and skin care effect.SAS has good decontamination and emulsifying ability, biology drop
Solution property is splendid, is a kind of green, non-stimulated anion surfactant.Dodecyl Glucoside has that wetting power is strong, detergency
Significantly, it is non-stimulated to skin, it is biodegradable good the advantages of, and compatibility is good, have to skin certain protective role it is non-from
Sub- surfactant.
The present invention is sugared by aliphatic acid sodium isethionate and SAS anion surfactant and dodecyl
Glycosides nonionic surfactant compounding use, make obtained hand cleanser have foam it is soft and smooth it is fine and smooth, non-stimulated, do not hurt hands, and
The advantages of dirt-removing power is strong, the effect for fast and effectively cleaning both hands can be reached.
Folium Artemisiae Argyi extract in anti-bacterial hand lotion provided by the invention containing Folium Artemisiae Argyi extract contain abundant volatile oil,
Flavones, eudesmane and triterpene substance, it has bactericidal properties and antianaphylaxis.The main component of Lonicera confusa extract is chlorogenic acid
And there is higher radicals scavenging to act on for galuteolin, both compositions.Herba Plantaginis extract is to Trichophyton concentricum, wool
Shape microsporum, starlike slave card bacterium have different degrees of inhibitory action, are a kind of preferable plant extracts of bactericidal effect.
Folium Artemisiae Argyi extract, Lonicera confusa extract and Herba Plantaginis extract are mixed to be added to and washed by the present invention by certain weight ratio
In hand liquid, the bactericidal action of hand cleanser can be significantly improved, be found through experiment, it is provided by the invention containing Folium Artemisiae Argyi extract
Anti-bacterial hand lotion reaches more than 96% to the sterilizing rate of staphylococcus aureus, Escherichia coli and Candida albicans, it was demonstrated that this is washed
Hand liquid has stronger sterilizing ability.
In addition, the anti-bacterial hand lotion provided by the invention containing Folium Artemisiae Argyi extract also added NMF and jojoba oil,
The NMF is mixed by sodium lactate and glycerine, has preferable moisturizing, moisturizing effects.Jojoba oil is rich in vitamin
E and mineral matter, enough nutrition can be provided for skin, and jojoba oil can also be paved into a tunic in skin surface, can
Effectively to pin moisture and reach the effect of moisturizing.After the hand cleanser use, there is moist, moisturizing to skin, can be with
It is effective to prevent that the phenomenon dried, peeled occurs in skin after using hand cleanser.
In addition, present invention also offers a kind of preparation method of the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract, including it is following
Step：
S1 adds water to aliphatic acid sodium isethionate, SAS, Dodecyl Glucoside, NMF and Jojoba
Mixed in oil, stirring is to being completely dissolved；
S2 adds plant extracts, tetrasodium ethylenediamine tetraacetate, citric acid in the mixed liquor that step S1 is obtained, and stirring is equal
It is even；
In the mixed liquor that S3 obtains sodium chloride addition step S2, adjustment liquid viscosity is 2500-2800mPa.s, is produced.
Compared with prior art, the anti-bacterial hand lotion provided by the invention containing Folium Artemisiae Argyi extract has the advantage that：
（1）Anti-bacterial hand lotion provided by the invention containing Folium Artemisiae Argyi extract uses anion surfactant and nonionic
Surfactant compound uses, make obtained hand cleanser have foam it is soft and smooth it is fine and smooth, non-stimulated, do not hurt hands, and dirt-removing power
The advantages of strong, the effect for fast and effectively cleaning both hands can be reached；
（2）Anti-bacterial hand lotion provided by the invention containing Folium Artemisiae Argyi extract has the antibacterial action of wide spectrum, and will not
It is a kind of healthy, non-stimulated anti-bacterial hand lotion to skin irritant；
（3）Anti-bacterial hand lotion provided by the invention containing Folium Artemisiae Argyi extract with the addition of NMF and jojoba oil, use
There is moist, moisturizing to skin afterwards, can effectively prevent that the phenomenon dried, peeled occurs in skin after using hand cleanser.
Embodiment：
Below by way of the description of embodiment, the invention will be further described, but this is not the limit to the present invention
System, those skilled in the art according to the present invention basic thought, various modifications may be made or improve, but without departing from this
The basic thought of invention, within the scope of the present invention.The each component of the present invention is conventional commercial product, such as：Fat
Sour sodium isethionate is purchased from Taiwan Strait Exchange Association and led to（Group）Co., Ltd, model Yi Jiebang A；Jojoba oil is purchased from Hubei Xing Hehua
Work raw material Co., Ltd, No. CAS is：61789-91-1；Folium Artemisiae Argyi extract is purchased from Xi'an Bioisystech Co., Ltd of Tianrui, scientific name
For：Folium Artemisiae；Lonicera confusa extract is purchased from Xi'an Sai Ao Bioisystech Co., Ltd, and scientific name is
Lonicerae；Herba Plantaginis extract, which is purchased from, receives Tu Ruikesi commerce and trade (Shanghai) Co., Ltd., scientific name Pkabtagi
kabceikata。
Embodiment 1, a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
The anti-bacterial hand lotion containing Folium Artemisiae Argyi extract includes following components and its parts by weight：
8 parts of aliphatic acid sodium isethionate, 6 parts of SAS, 7 parts of Dodecyl Glucoside, 2 parts of NMF, plant
1 part of extract, 0.1 part of tetrasodium ethylenediamine tetraacetate, 0.05 part of sodium chloride, 0.1 part of citric acid, 0.02 part of jojoba oil and water 70
Part；The NMF is by sodium lactate and glycerine by volume 1:1 composition, the plant extracts is by Folium Artemisiae Argyi extract, Honeysuckle flower
Extract and Herba Plantaginis extract are by weight 2:0.5:1 composition.
Preparation method：
S1 adds water to aliphatic acid sodium isethionate, SAS, Dodecyl Glucoside, NMF and Jojoba
Mixed in oil, stirring is to being completely dissolved；
S2 adds plant extracts, tetrasodium ethylenediamine tetraacetate, citric acid in the mixed liquor that step S1 is obtained, and stirring is equal
It is even；
In the mixed liquor that S3 obtains sodium chloride addition step S2, adjustment liquid viscosity is 2500mPa.s, is produced.
Embodiment 2, a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
The anti-bacterial hand lotion containing Folium Artemisiae Argyi extract includes following components and its parts by weight：
10 parts of aliphatic acid sodium isethionate, 7 parts of SAS, 12 parts of Dodecyl Glucoside, 2 parts of NMF, plant
2 parts of thing extract, 0.5 part of tetrasodium ethylenediamine tetraacetate, 0.2 part of sodium chloride, 0.4 part of citric acid, 0.04 part of jojoba oil and water
80 parts；The NMF is by sodium lactate and glycerine by volume 1:2 compositions, the plant extracts is by Folium Artemisiae Argyi extract, mountain silver
Flower extract and Herba Plantaginis extract are by weight 3:1:1.5 composition.
Preparation method such as embodiment 1 is similar.
Embodiment 3, a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
The anti-bacterial hand lotion containing Folium Artemisiae Argyi extract includes following components and its parts by weight：
12 parts of aliphatic acid sodium isethionate, 10 parts of SAS, 15 parts of Dodecyl Glucoside, 3 parts of NMF, plant
3 parts of thing extract, 0.8 part of tetrasodium ethylenediamine tetraacetate, 0.03 part of sodium chloride, 0.8 part of citric acid, 0.06 part of jojoba oil and water
90 parts；The NMF is by sodium lactate and glycerine by volume 2:3 compositions, the plant extracts is by Folium Artemisiae Argyi extract, mountain silver
Flower extract and Herba Plantaginis extract are by weight 4:2:1 composition.
Preparation method such as embodiment 1 is similar.
Comparative example 1, a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
The anti-bacterial hand lotion containing Folium Artemisiae Argyi extract includes following components and its parts by weight：
7 parts of SAS, 12 parts of Dodecyl Glucoside, 2 parts of NMF, 2 parts of plant extracts, ethylenediamine tetra-acetic acid
80 parts of four 0.5 part of sodium, 0.2 part of sodium chloride, 0.4 part of citric acid, 0.04 part of jojoba oil and water；The NMF by sodium lactate and
Glycerine by volume 1:2 compositions, the plant extracts is by Folium Artemisiae Argyi extract, Lonicera confusa extract and Herba Plantaginis extract by weight
Measure ratio 3:1:1.5 composition.
Preparation method such as embodiment 1 is similar.
Comparative example 2, a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
The anti-bacterial hand lotion containing Folium Artemisiae Argyi extract includes following components and its parts by weight：
10 parts of aliphatic acid sodium isethionate, 12 parts of Dodecyl Glucoside, 2 parts of NMF, 2 parts of plant extracts, second two
80 parts of 0.5 part of four sodium of amine tetraacethyl, 0.2 part of sodium chloride, 0.4 part of citric acid, 0.04 part of jojoba oil and water；The NMF by
Sodium lactate and glycerine by volume 1:2 compositions, the plant extracts are carried by Folium Artemisiae Argyi extract, Lonicera confusa extract and Asiatic plantain
Thing is taken by weight 3:1:1.5 composition.
Preparation method such as embodiment 1 is similar.
Comparative example 3, a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
The anti-bacterial hand lotion containing Folium Artemisiae Argyi extract includes following components and its parts by weight：
10 parts of aliphatic acid sodium isethionate, 7 parts of SAS, 12 parts of Dodecyl Glucoside, 2 parts of NMF, plant
2 parts of thing extract, 0.5 part of tetrasodium ethylenediamine tetraacetate, 0.2 part of sodium chloride, 0.4 part of citric acid, 0.04 part of jojoba oil and water
80 parts；The NMF is by sodium lactate and glycerine by volume 1:2 compositions, the plant extracts is by Folium Artemisiae Argyi extract and Chinese herbaceous peony
Careless extract is by weight 3:2.5 composition.
Preparation method such as embodiment 1 is similar.
Comparative example 4, a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
The anti-bacterial hand lotion containing Folium Artemisiae Argyi extract includes following components and its parts by weight：
10 parts of aliphatic acid sodium isethionate, 7 parts of SAS, 12 parts of Dodecyl Glucoside, 2 parts of NMF, plant
2 parts of thing extract, 0.5 part of tetrasodium ethylenediamine tetraacetate, 0.2 part of sodium chloride, 0.4 part of citric acid, 0.04 part of jojoba oil and water
80 parts；The NMF is by sodium lactate and glycerine by volume 1:2 compositions, the plant extracts is by Folium Artemisiae Argyi extract, mountain silver
Flower extract and Herba Plantaginis extract are by weight 1:2:2 compositions.
Preparation method such as embodiment 1 is similar.
The gross activity thing assay experiment of test example one, anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
1st, test material：Prepared by embodiment 1, embodiment 2, embodiment 3, comparative example 1 and comparative example 2 extracts containing folium artemisiae argyi
The anti-bacterial hand lotion of thing.
2nd, test method：
With reference to 8.1 prescriptive procedure in GB/T13173.2-2000 to embodiment 1, embodiment 2, embodiment 3, comparative example
1 and the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract for preparing of comparative example 2 carry out gross activity thing assay.
3rd, result of the test：Result of the test is as shown in table 1.
The gross activity thing assay data of anti-bacterial hand lotion of the table 1 containing Folium Artemisiae Argyi extract
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 1 | Comparative example 2 | |
| Gross activity thing content | 9.7 | 9.9 | 9.8 | 9.0 | 9.2 |
As shown in Table 1, the present invention uses aliphatic acid sodium isethionate and SAS anion surfactant
With Dodecyl Glucoside nonionic surfactant compounding use compounding use, the gross activity thing content of hand cleanser can be improved,
So as to strengthen the detergency of hand cleanser, its detergency is than single fat acid sodium isethionate or SAS anion table
Face activating agent and the clean effect of Dodecyl Glucoside nonionic surfactant compounding use are good.
Test example two, the sterilization test of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
1st, test material：Prepared by embodiment 1, embodiment 2, embodiment 3, comparative example 3 and comparative example 4 extracts containing folium artemisiae argyi
The anti-bacterial hand lotion of thing.
2nd, test method：
With reference to 15979-2002《Disposable Sanitary Accessory sanitary standard》The method for disinfection measure embodiment 1 of appendix C,
Anti-bacterial hand lotion containing Folium Artemisiae Argyi extract prepared by embodiment 2, embodiment 3, comparative example 3 and comparative example 4 is to golden yellow grape
The effect of coccus, Escherichia coli and Candida albicans, calculate sterilizing rate（%）.
3rd, result of the test：Result of the test is as shown in table 2.
The sterilizing rate of anti-bacterial hand lotion of the table 2 containing Folium Artemisiae Argyi extract（%）Data
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 3 | Comparative example 4 | |
| Staphylococcus aureus（%） | 98.89% | 99.54% | 99.12% | 85.78% | 89.98% |
| Escherichia coli（%） | 99.23% | 99.86% | 99.49% | 86.61% | 90.57% |
| Candida albicans（%） | 96.45% | 97.28% | 96.64% | 75.58% | 87.83% |
As shown in Table 2, the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract that prepared by the present invention is to staphylococcus aureus, large intestine
Bacillus and Candida albicans sterilizing rate reach more than 96%, it was demonstrated that the hand cleanser has stronger sterilizing ability.With comparative example pair
Than that can obtain：Comparative example 3 lacks Lonicera confusa extract, and its sterilizing rate to Candida albicans is relatively low, and the golden yellow Portugal of comparative example 4
The bactericidal action of grape coccus, Escherichia coli and Candida albicans is below embodiment 1-3 bactericidal effect, illustrates that folium artemisiae argyi is extracted
Thing, Lonicera confusa extract and Herba Plantaginis extract show the cooperative effect of sterilization in certain proportion, can be significantly
Raising sterilizing rate.
The skin irritation test of test example three, anti-bacterial hand lotion containing Folium Artemisiae Argyi extract
1st, test material：Anti-bacterial hand lotion containing Folium Artemisiae Argyi extract prepared by embodiment 1, embodiment 2 and embodiment 3.
2nd, test method：
With reference to《Cosmetics health specification》（Version in 2007）Method of testing measure embodiment 1, the embodiment of skin irritation
2 and embodiment 3 prepare the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract to the irritant effects of skin, dermoreaction is commented
Point.
3rd, result of the test：
Drawn through dermoreaction scoring, the antibacterial containing Folium Artemisiae Argyi extract prepared by embodiment 1, embodiment 2 and embodiment 3
The integral estimation of hand cleanser is respectively less than 0.5, to no skin irritation.
Claims (4)
1. a kind of anti-bacterial hand lotion containing Folium Artemisiae Argyi extract, it is characterised in that including following components and its parts by weight：
Aliphatic acid sodium isethionate 8-12 parts, SAS 6-10 parts, Dodecyl Glucoside 7-15 parts, NMF 1-4
Part, plant extracts 1-3 parts, tetrasodium ethylenediamine tetraacetate 0.1-1 parts, sodium chloride 0.02-0.5 parts, citric acid 0.1-1 parts, suddenly
Bar oily 0.02-0.08 parts and water 70-90 parts suddenly；The NMF is by sodium lactate and glycerine 1-2 by volume:1-3 is formed；It is described
Plant extracts is by Folium Artemisiae Argyi extract, Lonicera confusa extract and Herba Plantaginis extract by weight 2-4:0.5-2:1-2 is formed.
2. the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract as claimed in claim 1, it is characterised in that including following components and its
Parts by weight：
10 parts of aliphatic acid sodium isethionate, 7 parts of SAS, 12 parts of Dodecyl Glucoside, 2 parts of NMF, plant carry
Take 80 parts of 2 parts of thing, 0.5 part of tetrasodium ethylenediamine tetraacetate, 0.2 part of sodium chloride, 0.4 part of citric acid, 0.04 part of jojoba oil and water.
3. the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract as claimed in claim 1, it is characterised in that the NMF is by lactic acid
Sodium and glycerine by volume 1:2 compositions.
4. the anti-bacterial hand lotion containing Folium Artemisiae Argyi extract as claimed in claim 1, it is characterised in that the plant extracts by
Folium Artemisiae Argyi extract, Lonicera confusa extract and Herba Plantaginis extract are by weight 3:1:1.5 composition.
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| CN108078815A (en) * | 2017-12-01 | 2018-05-29 | 吴义峰 | A kind of disposable hand cleanser of natural bacteriostatic and preparation method thereof |
| CN109953909A (en) * | 2017-12-25 | 2019-07-02 | 浙江神英科技有限公司 | A kind of anti-bacteria wet keeping hand cleanser |
| CN108379151A (en) * | 2018-04-13 | 2018-08-10 | 南京正宽医药科技有限公司 | A kind of plant hand sanitizer |
| CN109288771A (en) * | 2018-10-30 | 2019-02-01 | 云南顺心生物科技有限公司 | A kind of plant type Chinese medicine washing product |
| CN110051793A (en) * | 2019-05-09 | 2019-07-26 | 青岛大学附属医院 | A kind of skin radiation injury protective agent and preparation method thereof |
| CN111449999A (en) * | 2020-04-03 | 2020-07-28 | 广州暨南生物医药研究开发基地有限公司 | A hand sanitizer containing folium Artemisiae Argyi extract, and its preparation method |
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| DE102009028156A1 (en) * | 2009-07-31 | 2011-02-03 | Evonik Stockhausen Gmbh | Foamable O / W emulsion |
| CN104825356B (en) * | 2015-04-30 | 2016-10-19 | 威莱(广州)日用品有限公司 | A kind of anti-bacterial hand lotion and preparation method thereof |
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