CN103505384A - Antibacterial skin-moisturizing hand-washing liquid - Google Patents
Antibacterial skin-moisturizing hand-washing liquid Download PDFInfo
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- CN103505384A CN103505384A CN201210210653.3A CN201210210653A CN103505384A CN 103505384 A CN103505384 A CN 103505384A CN 201210210653 A CN201210210653 A CN 201210210653A CN 103505384 A CN103505384 A CN 103505384A
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Abstract
The invention relates to the field of biological pharmacy, and provides an antibacterial skin-moisturizing hand-washing liquid which is characterized by comprising the components: surfactants comprising 1, an anionic surfactant (a) with the weight accounting for 2.0-15% of the weight of the total components, 2, an anionic surfactant (b) with the weight accounting for 1.0-10.0% of the weight of the total components, and 3, an nonionic surfactant with the weight accounting for 1.5-20% of the weight of the total components; 4, a moisturizing agent with the weight accounting for 0.5-10% of the weight of the total components; 5, a bioactive factor with the weight accounting for 0.5-10% of the weight of the total components; 6, a chelating agent with the weight accounting for 0.05-1.0% of the weight of the total components; 7, an antibacterial agent with the weight accounting for 0.05-5.0% of the weight of the total components; and 8, the balance being water. The antibacterial skin-moisturizing hand-washing liquid can be used in skin disinfection and sterilization and a cleaning agent and the like.
Description
Technical field
The invention belongs to field of biological pharmacy, is a kind of antibiotic skin moistening liquid soap.
Background technology
In recent years, along with improving constantly of people's prevent disease consciousness, the market various handwashing liquid of raising variety has also entered into life gradually, yet most of function is more single, and its prescription nearly all be take chemical medicine as main, and large to the zest of skin, antibacterial effect is poor.For detergency, and gentleness do not stimulate, and antibacterial bacteriostatic skin protection moisturizer is more and more subject to people's favor, and has very wide market development space.
Summary of the invention
The present invention is a kind of antibiotic skin moistening liquid soap.It mainly comprises: 1. anion surfactant (a) accounts for total composition weight 2.0～15%.2. anion surfactant (b) accounts for total composition 1.0～10.0%.3. non-ionic surface active agent accounts for 1.5～20% of total composition weight.4 wetting agents account for total composition weight 0.5～10%.5. bioactie agent accounts for 0.5～10% of total composition weight.6. chelating agen accounts for total composition weight 0.05～1.0%.7. antibacterial accounts for total composition weight 0.05～5.0%.Surplus is water.
Unless otherwise indicated, all percent of the present invention all calculates with the weight of compositions, and all ratios are all weight ratios.
The advantages such as anion surfactant of the present invention (a) is sodium lauryl sulphate, and content is 2.0～15%, and tool emulsifying disperses, and sterilization reduces surface tension, and compatibility is better.(b) be polyoxyethylenated alcohol sodium sulfate, content is 1.0～10.0%, and character is gentle, and anti-performance of hard water is good, and both interworkings can effectively reduce the zest of handwashing liquid, strengthens foaming characteristic and the dirt-removing power of this product.
Non-ionic surface active agent of the present invention is alkyl polyglucoside, content is 1.5～20%, a kind of pure natural surfactant, stable in properties, moisturizing moistening function is remarkable, be easy to biodegradation, the pollution of reduction to environment, can reduce the zest of handwashing liquid with above-mentioned anion surfactant compatibility, and foam is abundant, fine and smooth gentleness is not dry and astringent, does not have greasy or dry sensation after washing hands.Alkyl polyglucoside has stronger broad spectrum antibiotic activity, can increase the antibacterial effect of this handwashing liquid, extends the bacteriostasis time.
Wetting agent of the present invention is glycerol, and content is 0.5～10%.
Bioactie agent of the present invention is Aloe extract; content is 0.5～10%; Aloe is herbaceos perennial; its extract (as tinctura aloes, Aloe polysaccharide, multivitamin etc.) has many compositions to have good nutrition to moisten effect to human body skin; and nonirritant, with rear comfortable, can play nutrition to skin as the additive of this handwashing liquid; moisten protective effect such as antibacterial grade.
Chelating agen of the present invention is sodium citrate, and content is 0.05～1.0%.So that the washing of product adaptation under hard water environment, also tool regulates PH function simultaneously.
The present invention also includes the acceptable a small amount of thickening agent of handwashing liquid, PH regulator, antiseptic, spice, pigment etc.PH regulator is citric acid, adjusts pH value to 5.5～6.5.
The specific embodiment
Preparation process is as follows: anion surfactant (a) sodium lauryl sulphate is joined in retort, add appropriate water, add again anion surfactant (b) polyoxyethylenated alcohol sodium sulfate, be heated to 80 ± 2 ℃, be stirred well to completely and dissolve, add successively non-ionic surface active agent alkyl polyglucoside, wetting agent, chelating agen, continue to be stirred to cooling, in the time of below 40 ℃, add Aloe extract, tea tree oil, essence, antiseptic, add citric acid to regulate PH to 5.5～7.0, finally by NaCl, be adjusted to needed viscosity, after fully stirring, fill.This product can be added various suitable essence and pigment as required, to beautify outward appearance.
Below implementing all percent all calculates with the weight ratio of compositions.
Implement one:
Implement two:
Implement three:
Implement four:
Implement five:
Effect evaluation to embodiment:
1. Evaluation of Germicidal Efficacy
In a kind of antibiotic skin moistening liquid soap of the present invention, Aloe, tea tree oil all have bactericidal effect, especially in tea tree oil, contain various ingredients and there is Synergistic fungicidal active, the antibacterium with wide spectrum, remove fastbacteria, antifungal, antiviral isoreactivity, in daily use chemicals, medicine and other fields application is comparatively extensive.
The bactericidal property of the antibiotic skin moistening liquid soap of table 1. (5.0%) diluent
Note: the average clump count of staphylococcus aureus positive controls is 1790000cfu/ sheet, the average clump count of Candida albicans positive controls is 1720000/, the average clump count of escherichia coli positive controls is 865000cfu/ sheet, and each organizes the equal zero growth of negative control.
2. sensory evaluation
20 testers are equally divided into 5 groups, by " double blinding " experiment, give immediately test group sample, requiring tester to wash one's hands by self daily custom of washing one's hands (is handwashing liquid consumption, Handwashing ways, the bath time does not limit), evaluate successively this handwashing liquid foaming characteristic, dirt-removing power, zest, flushing difficulty, wash rear salubrious sense, tester according to oneself feel mark, standards of grading adopt ten point system, wherein foaming characteristic, dirt-removing power, to wash rear salubrious sense the poorest with 1 minute, 10 minutes are best; Zest, to rinse difficulty best with 1 minute, the poorest calculating in 10 minutes, the sensory effects scoring of finally recording each specific embodiment with mean values.
The sensory evaluation of a table 2 antibiotic skin moistening liquid soap hand-washing effect
Claims (3)
1. an antibiotic skin moistening liquid soap, is characterised in that 1. it comprise. anion surface active (a) agent accounts for total composition weight 2.0～15%.2.. anion surfactant (b) accounts for total composition 1.0～10.0%.3.. non-ionic surface active agent accounts for 1.5～20% of total composition weight.4.. wetting agent accounts for total composition weight 0.5～10%.5.. bioactie agent accounts for 0.5～10% of total composition weight.6.. chelating agen accounts for total composition weight 0.05～1.0%.7.. antibacterial accounts for total composition weight 0.05～5.0%.8. surplus is water.
2. according to claim 1, it is characterized by the surfactant in antibiotic skin moistening liquid soap, 1.. anion surfactant (a) is sodium lauryl sulphate; 2.. anion surfactant.
3. according to claim 2, it is characterized in that providing a kind of antibiotic skin moistening liquid soap of many effects that contains natural surfactant, natural herb plant extract.This handwashing liquid character is gentle, and zest is little, and nourishing and moisturizing hand skin has good antibacterial bacteriostatic ability simultaneously, and resistance to hard water is strong, the gentle advantage such as fine and smooth of feel during washing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210210653.3A CN103505384A (en) | 2012-06-25 | 2012-06-25 | Antibacterial skin-moisturizing hand-washing liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201210210653.3A CN103505384A (en) | 2012-06-25 | 2012-06-25 | Antibacterial skin-moisturizing hand-washing liquid |
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| CN103505384A true CN103505384A (en) | 2014-01-15 |
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| CN201210210653.3A Pending CN103505384A (en) | 2012-06-25 | 2012-06-25 | Antibacterial skin-moisturizing hand-washing liquid |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989623A (en) * | 2014-06-13 | 2014-08-20 | 云南白药清逸堂实业有限公司 | Functional female care washing liquor by using probiotics and preparation method of functional female care washing liquor |
| CN104095789A (en) * | 2014-07-08 | 2014-10-15 | 贾会春 | Special Chinese honey locust liquid soap used in clinical laboratory and preparation method thereof |
| CN104940063A (en) * | 2015-06-15 | 2015-09-30 | 韩进 | Medical liquid soap |
| CN105708764A (en) * | 2016-03-24 | 2016-06-29 | 攀柔莎（江苏）生物科技股份有限公司 | Liquid soap containing aloe extract |
| CN106214513A (en) * | 2016-08-29 | 2016-12-14 | 山东新华医疗器械股份有限公司 | Medical worker is with faintly acid handwashing liquid and preparation method thereof |
| CN106726956A (en) * | 2016-12-23 | 2017-05-31 | 严志海 | A kind of antibacterial skin moistening liquid soap and preparation method thereof |
| CN108434006A (en) * | 2017-02-16 | 2018-08-24 | 天津国际生物医药联合研究院 | A kind of leakage of liquid and preparation method thereof of prevention hand-foot-and-mouth disease |
| CN108434008A (en) * | 2017-02-16 | 2018-08-24 | 天津国际生物医药联合研究院 | A kind of foam liquid soap and preparation method thereof of prevention hand-foot-and-mouth disease |
| CN108434007A (en) * | 2017-02-16 | 2018-08-24 | 天津国际生物医药联合研究院 | A kind of disposable foam liquid soap and preparation method thereof of prevention hand-foot-and-mouth disease |
| CN108589281A (en) * | 2018-03-23 | 2018-09-28 | 江苏宇道生物科技有限公司 | A kind of novel surfactant system and preparation method thereof |
| CN111067814A (en) * | 2019-10-30 | 2020-04-28 | 广州市浪奇实业股份有限公司 | Antibacterial skin cleaning product |
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| CN1114181A (en) * | 1994-06-28 | 1996-01-03 | 乌力吉 | 6-in-1 long-acting nutritious shampoo containing extract liquid of snail |
| CN101475879A (en) * | 2009-01-19 | 2009-07-08 | 广东拉芳日化有限公司 | Sterilizing skin-protective hand cleanser |
| CN102423291A (en) * | 2011-12-30 | 2012-04-25 | 山西振东制药股份有限公司 | Traditional Chinese medicine antibiotic skincare hand cleanser and preparation method thereof |
-
2012
- 2012-06-25 CN CN201210210653.3A patent/CN103505384A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1114181A (en) * | 1994-06-28 | 1996-01-03 | 乌力吉 | 6-in-1 long-acting nutritious shampoo containing extract liquid of snail |
| CN101475879A (en) * | 2009-01-19 | 2009-07-08 | 广东拉芳日化有限公司 | Sterilizing skin-protective hand cleanser |
| CN102423291A (en) * | 2011-12-30 | 2012-04-25 | 山西振东制药股份有限公司 | Traditional Chinese medicine antibiotic skincare hand cleanser and preparation method thereof |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989623A (en) * | 2014-06-13 | 2014-08-20 | 云南白药清逸堂实业有限公司 | Functional female care washing liquor by using probiotics and preparation method of functional female care washing liquor |
| CN103989623B (en) * | 2014-06-13 | 2016-08-24 | 云南白药清逸堂实业有限公司 | A kind of functional Feminine care lotion applying probiotic bacteria and preparation method |
| CN104095789A (en) * | 2014-07-08 | 2014-10-15 | 贾会春 | Special Chinese honey locust liquid soap used in clinical laboratory and preparation method thereof |
| CN104940063A (en) * | 2015-06-15 | 2015-09-30 | 韩进 | Medical liquid soap |
| CN105708764A (en) * | 2016-03-24 | 2016-06-29 | 攀柔莎（江苏）生物科技股份有限公司 | Liquid soap containing aloe extract |
| CN106214513A (en) * | 2016-08-29 | 2016-12-14 | 山东新华医疗器械股份有限公司 | Medical worker is with faintly acid handwashing liquid and preparation method thereof |
| CN106726956A (en) * | 2016-12-23 | 2017-05-31 | 严志海 | A kind of antibacterial skin moistening liquid soap and preparation method thereof |
| CN108434006A (en) * | 2017-02-16 | 2018-08-24 | 天津国际生物医药联合研究院 | A kind of leakage of liquid and preparation method thereof of prevention hand-foot-and-mouth disease |
| CN108434008A (en) * | 2017-02-16 | 2018-08-24 | 天津国际生物医药联合研究院 | A kind of foam liquid soap and preparation method thereof of prevention hand-foot-and-mouth disease |
| CN108434007A (en) * | 2017-02-16 | 2018-08-24 | 天津国际生物医药联合研究院 | A kind of disposable foam liquid soap and preparation method thereof of prevention hand-foot-and-mouth disease |
| CN108589281A (en) * | 2018-03-23 | 2018-09-28 | 江苏宇道生物科技有限公司 | A kind of novel surfactant system and preparation method thereof |
| CN111067814A (en) * | 2019-10-30 | 2020-04-28 | 广州市浪奇实业股份有限公司 | Antibacterial skin cleaning product |
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Application publication date: 20140115 |