CN105193645A - Sterilization liquid soap - Google Patents
Sterilization liquid soap Download PDFInfo
- Publication number
- CN105193645A CN105193645A CN201510561249.4A CN201510561249A CN105193645A CN 105193645 A CN105193645 A CN 105193645A CN 201510561249 A CN201510561249 A CN 201510561249A CN 105193645 A CN105193645 A CN 105193645A
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- CN
- China
- Prior art keywords
- hand cleanser
- disinfection hand
- cleanser according
- parts
- disinfection
- Prior art date
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- Granted
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- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 29
- 239000007788 liquid Substances 0.000 title abstract description 29
- 230000001954 sterilising effect Effects 0.000 title abstract description 16
- 239000000344 soap Substances 0.000 title abstract description 4
- 239000004094 surface-active agent Substances 0.000 claims abstract description 5
- 239000002562 thickening agent Substances 0.000 claims abstract description 3
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical compound C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 claims description 18
- 230000000844 anti-bacterial effect Effects 0.000 claims description 14
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- OSDLLIBGSJNGJE-UHFFFAOYSA-N 4-chloro-3,5-dimethylphenol Chemical compound CC1=CC(O)=CC(C)=C1Cl OSDLLIBGSJNGJE-UHFFFAOYSA-N 0.000 claims description 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 8
- 239000012141 concentrate Substances 0.000 claims description 7
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 6
- -1 hydroxypropyl Chemical group 0.000 claims description 5
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 claims description 4
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 4
- 150000001408 amides Chemical class 0.000 claims description 4
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 4
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 4
- 235000019864 coconut oil Nutrition 0.000 claims description 4
- 239000003240 coconut oil Substances 0.000 claims description 4
- 239000008367 deionised water Substances 0.000 claims description 4
- 229910021641 deionized water Inorganic materials 0.000 claims description 4
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 claims description 4
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 4
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 4
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 4
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 4
- 239000011780 sodium chloride Substances 0.000 claims description 4
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 4
- 235000011152 sodium sulphate Nutrition 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical group CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 claims description 3
- DHHFDKNIEVKVKS-MVUYWVKGSA-N Betanin Natural products O=C(O)[C@@H]1NC(C(=O)O)=C/C(=C\C=[N+]/2\[C@@H](C(=O)[O-])Cc3c\2cc(O)c(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)c3)/C1 DHHFDKNIEVKVKS-MVUYWVKGSA-N 0.000 claims description 3
- FPVVYTCTZKCSOJ-UHFFFAOYSA-N Ethylene glycol distearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCCCCCCCCC FPVVYTCTZKCSOJ-UHFFFAOYSA-N 0.000 claims description 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 3
- 235000012677 beetroot red Nutrition 0.000 claims description 3
- 239000001654 beetroot red Substances 0.000 claims description 3
- 235000002185 betanin Nutrition 0.000 claims description 3
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 3
- 235000010234 sodium benzoate Nutrition 0.000 claims description 3
- 239000004299 sodium benzoate Substances 0.000 claims description 3
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 2
- 230000002421 anti-septic effect Effects 0.000 claims description 2
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 2
- 229940071826 hydroxyethyl cellulose Drugs 0.000 claims description 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 2
- 239000003002 pH adjusting agent Substances 0.000 claims description 2
- 235000013599 spices Nutrition 0.000 claims description 2
- 238000005406 washing Methods 0.000 abstract description 3
- 230000007935 neutral effect Effects 0.000 abstract description 2
- 239000002738 chelating agent Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 230000003020 moisturizing effect Effects 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 239000002002 slurry Substances 0.000 abstract 1
- 239000003206 sterilizing agent Substances 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 11
- 238000003756 stirring Methods 0.000 description 8
- 241000191967 Staphylococcus aureus Species 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 241000588724 Escherichia coli Species 0.000 description 4
- 239000003085 diluting agent Substances 0.000 description 4
- 230000007613 environmental effect Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 239000003599 detergent Substances 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 230000001408 fungistatic effect Effects 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000006916 nutrient agar Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 239000006159 Sabouraud's agar Substances 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- VQLYBLABXAHUDN-UHFFFAOYSA-N bis(4-fluorophenyl)-methyl-(1,2,4-triazol-1-ylmethyl)silane;methyl n-(1h-benzimidazol-2-yl)carbamate Chemical compound C1=CC=C2NC(NC(=O)OC)=NC2=C1.C=1C=C(F)C=CC=1[Si](C=1C=CC(F)=CC=1)(C)CN1C=NC=N1 VQLYBLABXAHUDN-UHFFFAOYSA-N 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 230000009514 concussion Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000008233 hard water Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
- A61K2800/436—Interference pigments, e.g. Iridescent, Pearlescent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Detergent Compositions (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides sterilization liquid soap, which is prepared from the following ingredients in parts by weight: 10 to 25 parts of surface active agents, 0.5 to 5 parts of pearly slurry, 0.1 to 2 parts of sterilizing agents, 3 to 5 parts of thickening agents, 0.01 to 0.1 parts of preservatives, 0.01 to 1 part of chelating agents and 0.01 to 1 part of pH regulators. The sterilization liquid soap provided by the invention is neutral and does not have irritation, has the washing and sterilization functions and also has a skin moisturizing effect.
Description
Technical field
The present invention relates to washing field, particularly relate to a kind of disinfection hand cleanser.
Background technology
The eighties in 20th century, handwashing liquid starts to move towards family by the hotel in west, hotel, and is well known gradually, thus, worldwide obtains and promotes comparatively widely.1999, " ancestral's silk " handwashing liquid entered Chinese market, had broken the blank in Chinese handwashing liquid market.Have passed through the development of more than ten years, handwashing liquid has become widely known, becomes the requirement in people's life.At present, the handwashing liquid on market is of a great variety, but really environmental protection, sterilizing function are rolled into one less.
The patent of invention about handwashing liquid was applied for before the applicant, the application number of this patent application is CN201310005303.8, name is called a kind of sterilization moisture retention hand cleanser of environmental protection, compared to CN201310005303.8, the present invention has selected gentleer surfactant, and with the addition of Pearl Concentrate, and make product more attractive in appearance, non-stimulated.Antibacterial has selected parachlorometaxylenol (PCMX), and at least one in the chloro-2'-dihydroxy diphenyl ether (DP-300) of 2,4,4'-tri-, by experiment, this handwashing liquid is to staphylococcus aureus, and escherichia coli have good fungistatic effect.
Summary of the invention
The object of the invention is to solve the subproblem existed in existing handwashing liquid technology, a kind of disinfection hand cleanser is provided.
The object of the invention is to be achieved through the following technical solutions:
A kind of disinfection hand cleanser, comprises component and mass fraction is as follows:
Preferably, described disinfection hand cleanser comprises component and mass fraction is as follows:
Preferably, described surfactant is Dodecyl Polyoxyethylene Ether sodium sulfate, cocamido propyl betaine, at least one of coconut oil diethanol amide.
Preferably, described antibacterial is to chlorine Resorcino (PCMX), at least one in the chloro-2'-dihydroxy diphenyl ether (DP-300) of 2,4,4'-tri-.
Preferably, described thickening agent is at least one in hydroxyethyl-cellulose, hydroxypropyl emthylcellulose, sodium chloride.
Preferably, described chelating agen is at least one in ethylenediaminetetraacetic acid, disodium edta.
Preferably, described antiseptic is at least one in 1,3-dihydroxymethyl-5,5-dimethyl hydantoin (DMDMH), 2-methyl-4-isothiazoline-3 ketone (MIT), sodium benzoate.
Preferably, described pH adjusting agent is citric acid.
Preferably, described Pearl Concentrate is ether alcohol sulfate/Ethylene Glycol Distearate/alkanolamide/betanin compound.
Preferably, also containing essence or spice and deionized water.
Beneficial effect of the present invention: the handwashing liquid of the application is a kind of neutral handwashing liquid, sterilization does not hinder hands, has both had washing and sterilizing function, has had again skin moisture-keeping effect.Described Pearl Concentrate can produce obvious pearl effect.Described Pearl Concentrate is ether alcohol sulfate/Ethylene Glycol Distearate/alkanolamide/betanin compound, be a kind of liquid can the ethylene glycol stearate crystal of cold dispersion, for the pulpous state pearling agent of liquid detergent article.Dissolve or emulsifying after ethylene glycol stearate heats in surfactant complex, mirror flaky crystal can be separated out in temperature-fall period, thus produce nacreous lustre.For obvious pearl effect can be produced in handwashing liquid, and there is skin care, increase the effects such as the viscosity of product, make product more attractive in appearance than common handwashing liquid and attractive.Described antibacterial can effectively suppress staphylococcus aureus and escherichia coli.Described antibacterial is PCMX, PCMX is a kind of antimildew and antibacterial agent of wide spectrum, to most Gram-positive, negative bacterium, fungus, mycete kills effect, it can be used as antimildew and antibacterial agent and is widely used in sterilization or personal-care supplies, as anti-dandruff shampoo, in the antibacterial detergents such as handwashing liquid, soap and other hygienic article.In this handwashing liquid, the amount of interpolation is within the scope of 0.1%-2%, and to staphylococcus aureus, escherichia coli have stronger bacteriostasis.In this handwashing liquid, during PCMX0.5% content, to staphylococcus aureus, colibacillary bacteriostasis rate is all greater than 99%.DP-300 be praise highly in the world at present wide spectrum, efficiently, almost do not have virose sterilization, antibacterial., there is not any toxicity table disease and environmental pollution in its stable chemical performance, heatproof, weather-proof, that acid and alkali hydrolysis, is the specially good effect antibacterial kind of generally acknowledging in the world.In this handwashing liquid, the amount of interpolation has good bacteriostasis within the scope of 0.05%-2%.It is when 0.6% content, and to staphylococcus aureus, the bacteriostasis rate of large field bacillus is all greater than 99%.
Detailed description of the invention
In order to better the present invention is described, below the technical scheme in the embodiment of the present invention is clearly and completely described.
Embodiment 1
A kind of disinfection hand cleanser, its component and mass fraction thereof are:
The preparation method of a kind of disinfection hand cleanser of embodiment 1 is as follows:
1. add the deionized water 76.1 parts, the disodiumedetate 1 part that measure successively, stir and be warming up to 60 DEG C-70 DEG C, add 8 parts, Dodecyl Polyoxyethylene Ether sodium sulfate again, cocamido propyl betaine 6 parts, coconut oil diethanol amide 3 parts, stirring make it to dissolve.
2. be cooled to less than 30 DEG C, add Pearl Concentrate 2 parts, sodium benzoate 0.1 part, 0.2 part, essence, PCMX0.5 part, stir and make it to dissolve, regulate pH ≈ 7 with citric acid 0.1 part, then add 3 parts, sodium chloride, stir and make it to dissolve.
3. pack after filtering with 300 mesh filter screens.
Embodiment 2
A sterilization moisture retention hand cleanser for environmental protection, its component and mass fraction thereof are:
The preparation method of a kind of disinfection hand cleanser of embodiment 2 is as follows:
1. add the deionized water 74.52 parts, the disodiumedetate 1 part that measure successively, stir and be warming up to 60 DEG C-70 DEG C, add 5 parts, Dodecyl Polyoxyethylene Ether sodium sulfate again, cocamido propyl betaine 10 parts, coconut oil diethanol amide 2 parts, stirring make it to dissolve.
2. be cooled to less than 30 DEG C, add Pearl Concentrate 3 parts, DMDMH0.1 part, 0.1 part, essence, DP-300 (2,4, the chloro-2'-dihydroxy diphenyl ether of 4'-tri-) 0.2 part, stir and make it to dissolve, regulate pH ≈ 7 with citric acid 0.08 part, then add 4 parts, sodium chloride, stir and make it to dissolve.
3. pack after filtering with 300 mesh filter screens.
For proving the bactericidal effect of disinfection hand cleanser of the present invention, carry out following sterilization experiment.
1. experimental subject
Interpolation PCMX is the handwashing liquid of antibacterial is the handwashing liquid of antibacterial with adding DP-300.
2. collecting cells
2.1 test organismss: staphylococcus aureus ATCC6538, escherichia coli 8099
2.2 collecting cells: the nutrient agar inclined-plane fresh cultured thing getting strain the 5th generation, adds inclined-plane with 5mL diluent, wash lower lawn, and concussion mixing.
3. bacteriostatic test operating procedure
Test organisms suspension dilutes with PBS liquid by 3.1, requires that concentration is: get 0.1mL and drip in contrast sample liquid (PBS) 5.0mL, bacterial count recovered is 1 × 10
4~ 9 × 10
4cfu/mL;
Test specimen Sterile standard hard water is diluted to the concentration of regulation by 3.2;
3.3 absorption test specimen stock solutions or its diluent 5mL put into sterilizing test tubes, 20 DEG C of constant temperature 5min;
3.4 draw test organisms liquid 0.1mL joins in the test tube containing 5mL sample, mixes rapidly, and timing immediately;
3.5 effects, to setting-up time, are got the mixed liquor 0.1mL of test organisms and sample, are joined containing 5mL in the test tube of the PBS of sterilizing, mixing;
After 3.6 placement 10min, draw sample liquid (or after doing suitably dilution, getting the individual dilution diluent of wherein 2-3) 1mL, be placed in sterilizing plate, each sample liquid or diluent inoculate two sterilizing plates.Pour into cool nutrient agar (antibacterial) to 40-45 DEG C or (sabouraud's agar yeast) 15mL, rotate plate, make it full and uniform, plate is overturn after agar solidification, after (35 scholar 2) DEG C cultivates 48h (antibacterial) or 72h (yeast), do viable bacteria colony counting;
3.7 replace test specimen with PBS, simultaneously by above step operation, and sample in contrast;
3.8 experiments in triplicate, ask its meansigma methods.
4. evaluation criterion
Bacteriostasis rate >=50% ~ 90%, product has bacteriostasis, bacteriostasis rate >=90%, and product has stronger bacteriostasis.
5. antibacterial result
The evaluation of table 1 fungistatic effect
As shown in Table 1, handwashing liquid of the present invention is all greater than 99% to staphylococcus aureus and colibacillary bacteriostasis rate, has good bacteriostasis.
The above; be only the present invention's preferably detailed description of the invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; the change that can expect easily or replacement, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of claims.
Claims (10)
1. a disinfection hand cleanser, is characterized in that, comprises component and mass fraction is as follows:
2. disinfection hand cleanser according to claim 1, is characterized in that, comprises component and mass fraction is as follows:
3. disinfection hand cleanser according to claim 1 and 2, is characterized in that, described surfactant is Dodecyl Polyoxyethylene Ether sodium sulfate, cocamido propyl betaine, at least one of coconut oil diethanol amide.
4. disinfection hand cleanser according to claim 1 and 2, is characterized in that, described antibacterial is PCMX (parachlorometaxylenol), at least one in DP-300 (the chloro-2'-dihydroxy diphenyl ether of 2,4,4'-tri-).
5. disinfection hand cleanser according to claim 1 and 2, is characterized in that, described thickening agent is at least one in hydroxyethyl-cellulose, hydroxypropyl emthylcellulose, sodium chloride.
6. disinfection hand cleanser according to claim 1 and 2, is characterized in that, described chelating agen is at least one in ethylenediaminetetraacetic acid, disodium edta.
7. disinfection hand cleanser according to claim 1 and 2, it is characterized in that, described antiseptic is at least one in 1,3-dihydroxymethyl-5,5-dimethyl hydantoin (DMDMH), 2-methyl-4-isothiazoline-3 ketone (MIT), sodium benzoate.
8. disinfection hand cleanser according to claim 1 and 2, is characterized in that, pH adjusting agent is citric acid.
9. disinfection hand cleanser according to claim 1 and 2, is characterized in that, described Pearl Concentrate is ether alcohol sulfate/Ethylene Glycol Distearate/alkanolamide/betanin compound.
10. disinfection hand cleanser according to claim 1 and 2, is characterized in that, also containing essence or spice and deionized water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510561249.4A CN105193645B (en) | 2015-09-06 | 2015-09-06 | A kind of disinfection hand cleanser |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510561249.4A CN105193645B (en) | 2015-09-06 | 2015-09-06 | A kind of disinfection hand cleanser |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105193645A true CN105193645A (en) | 2015-12-30 |
| CN105193645B CN105193645B (en) | 2018-03-13 |
Family
ID=54941847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510561249.4A Expired - Fee Related CN105193645B (en) | 2015-09-06 | 2015-09-06 | A kind of disinfection hand cleanser |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105193645B (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106309347A (en) * | 2016-08-25 | 2017-01-11 | 攀柔莎（江苏）生物科技股份有限公司 | Foaming hand washing liquid containing enzymes |
| CN106465715A (en) * | 2016-09-22 | 2017-03-01 | 长兴净安环保科技有限公司 | A kind of multi-functional bacteria-removing liquid and preparation method thereof |
| CN106479698A (en) * | 2016-09-22 | 2017-03-08 | 长兴净安环保科技有限公司 | A kind of high-efficiency multi-function bacteria-removing liquid and preparation method thereof |
| CN107280997A (en) * | 2017-06-20 | 2017-10-24 | 江苏开源康达医疗器械有限公司 | A kind of composite lysozyme sterilization ora, disinfectant and preparation method thereof |
| CN108048240A (en) * | 2017-11-27 | 2018-05-18 | 武威霖沐科技发展有限公司 | A kind of production method of feature of environmental protection Green detergent |
| CN112315894A (en) * | 2020-11-19 | 2021-02-05 | 聂绪明 | EM (effective microorganisms) hand sanitizer and preparation method thereof |
| CN112494366A (en) * | 2020-09-26 | 2021-03-16 | 福建省梦娇兰日用化学品有限公司 | PCMX-containing bacteriostatic hand sanitizer for children and preparation method thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106309347A (en) * | 2016-08-25 | 2017-01-11 | 攀柔莎（江苏）生物科技股份有限公司 | Foaming hand washing liquid containing enzymes |
| CN106465715A (en) * | 2016-09-22 | 2017-03-01 | 长兴净安环保科技有限公司 | A kind of multi-functional bacteria-removing liquid and preparation method thereof |
| CN106479698A (en) * | 2016-09-22 | 2017-03-08 | 长兴净安环保科技有限公司 | A kind of high-efficiency multi-function bacteria-removing liquid and preparation method thereof |
| CN107280997A (en) * | 2017-06-20 | 2017-10-24 | 江苏开源康达医疗器械有限公司 | A kind of composite lysozyme sterilization ora, disinfectant and preparation method thereof |
| CN108048240A (en) * | 2017-11-27 | 2018-05-18 | 武威霖沐科技发展有限公司 | A kind of production method of feature of environmental protection Green detergent |
| CN112494366A (en) * | 2020-09-26 | 2021-03-16 | 福建省梦娇兰日用化学品有限公司 | PCMX-containing bacteriostatic hand sanitizer for children and preparation method thereof |
| CN112315894A (en) * | 2020-11-19 | 2021-02-05 | 聂绪明 | EM (effective microorganisms) hand sanitizer and preparation method thereof |
| CN113456545A (en) * | 2021-05-17 | 2021-10-01 | 江苏敖广日化集团股份有限公司 | Antibacterial hand sanitizer and preparation method thereof |
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| CN105193645B (en) | 2018-03-13 |
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