CN101099714B - Antibiotic hand-care liquid preparing method - Google Patents
Antibiotic hand-care liquid preparing method Download PDFInfo
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- CN101099714B CN101099714B CN2006100286358A CN200610028635A CN101099714B CN 101099714 B CN101099714 B CN 101099714B CN 2006100286358 A CN2006100286358 A CN 2006100286358A CN 200610028635 A CN200610028635 A CN 200610028635A CN 101099714 B CN101099714 B CN 101099714B
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- 239000007788 liquid Substances 0.000 title claims description 17
- 230000003115 biocidal effect Effects 0.000 title claims description 10
- 238000000034 method Methods 0.000 title description 2
- 239000004094 surface-active agent Substances 0.000 claims abstract description 14
- 230000002421 anti-septic effect Effects 0.000 claims abstract description 13
- 229960002233 benzalkonium bromide Drugs 0.000 claims abstract description 12
- 238000002360 preparation method Methods 0.000 claims abstract description 11
- 239000002671 adjuvant Substances 0.000 claims abstract description 5
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid group Chemical group C(CC(O)(C(=O)O)CC(=O)O)(=O)O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 21
- 238000003756 stirring Methods 0.000 claims description 18
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical group NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 14
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- KHSLHYAUZSPBIU-UHFFFAOYSA-M benzododecinium bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 KHSLHYAUZSPBIU-UHFFFAOYSA-M 0.000 claims description 11
- -1 propyl amide amine Chemical class 0.000 claims description 10
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 9
- SYELZBGXAIXKHU-UHFFFAOYSA-N dodecyldimethylamine N-oxide Chemical compound CCCCCCCCCCCC[N+](C)(C)[O-] SYELZBGXAIXKHU-UHFFFAOYSA-N 0.000 claims description 8
- NCBISIFFSNXYQJ-UHFFFAOYSA-N 1-dodecyl-4,5-dihydroimidazole Chemical compound CCCCCCCCCCCCN1CCN=C1 NCBISIFFSNXYQJ-UHFFFAOYSA-N 0.000 claims description 7
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 7
- 229960000458 allantoin Drugs 0.000 claims description 7
- 239000012752 auxiliary agent Substances 0.000 claims description 7
- 229960003237 betaine Drugs 0.000 claims description 7
- QCCKPZOPTXCJPL-UHFFFAOYSA-N dodecyl(dimethyl)azanium;hydroxide Chemical compound [OH-].CCCCCCCCCCCC[NH+](C)C QCCKPZOPTXCJPL-UHFFFAOYSA-N 0.000 claims description 7
- 150000003839 salts Chemical class 0.000 claims description 7
- 238000005303 weighing Methods 0.000 claims description 7
- OSDLLIBGSJNGJE-UHFFFAOYSA-N 4-chloro-3,5-dimethylphenol Chemical compound CC1=CC(O)=CC(C)=C1Cl OSDLLIBGSJNGJE-UHFFFAOYSA-N 0.000 claims description 6
- 239000008367 deionised water Substances 0.000 claims description 6
- 229910021641 deionized water Inorganic materials 0.000 claims description 6
- 239000000796 flavoring agent Substances 0.000 claims description 6
- 235000013355 food flavoring agent Nutrition 0.000 claims description 6
- 101000957776 Escherichia coli O157:H7 Mannose-1-phosphate guanylyltransferase 1 Proteins 0.000 claims description 5
- 239000003086 colorant Substances 0.000 claims description 5
- WOWHHFRSBJGXCM-UHFFFAOYSA-M cetyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)C WOWHHFRSBJGXCM-UHFFFAOYSA-M 0.000 claims description 4
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 4
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 238000004140 cleaning Methods 0.000 abstract description 5
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 description 10
- 238000004659 sterilization and disinfection Methods 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 230000000694 effects Effects 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 230000000844 anti-bacterial effect Effects 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 239000007864 aqueous solution Substances 0.000 description 5
- 235000015165 citric acid Nutrition 0.000 description 5
- 239000006260 foam Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000003599 detergent Substances 0.000 description 3
- 239000012467 final product Substances 0.000 description 3
- 231100000252 nontoxic Toxicity 0.000 description 3
- 230000003000 nontoxic effect Effects 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 230000002335 preservative effect Effects 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 229960000686 benzalkonium chloride Drugs 0.000 description 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 239000000576 food coloring agent Substances 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 229940051841 polyoxyethylene ether Drugs 0.000 description 2
- 229920000056 polyoxyethylene ether Polymers 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- OTEKOJQFKOIXMU-UHFFFAOYSA-N 1,4-bis(trichloromethyl)benzene Chemical compound ClC(Cl)(Cl)C1=CC=C(C(Cl)(Cl)Cl)C=C1 OTEKOJQFKOIXMU-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- DHHFDKNIEVKVKS-FMOSSLLZSA-N Betanin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC(C[C@H]2C([O-])=O)=C1[N+]2=C\C=C\1C=C(C(O)=O)N[C@H](C(O)=O)C/1 DHHFDKNIEVKVKS-FMOSSLLZSA-N 0.000 description 1
- DHHFDKNIEVKVKS-MVUYWVKGSA-N Betanin Natural products O=C(O)[C@@H]1NC(C(=O)O)=C/C(=C\C=[N+]/2\[C@@H](C(=O)[O-])Cc3c\2cc(O)c(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)c3)/C1 DHHFDKNIEVKVKS-MVUYWVKGSA-N 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 235000012677 beetroot red Nutrition 0.000 description 1
- 239000001654 beetroot red Substances 0.000 description 1
- 235000002185 betanin Nutrition 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 229960002152 chlorhexidine acetate Drugs 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 239000012954 diazonium Substances 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-O diazynium Chemical compound [NH+]#N IJGRMHOSHXDMSA-UHFFFAOYSA-O 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- MTNDZQHUAFNZQY-UHFFFAOYSA-N imidazoline Chemical compound C1CN=CN1 MTNDZQHUAFNZQY-UHFFFAOYSA-N 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000006166 lysate Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- ONLRKTIYOMZEJM-UHFFFAOYSA-N n-methylmethanamine oxide Chemical compound C[NH+](C)[O-] ONLRKTIYOMZEJM-UHFFFAOYSA-N 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 238000012372 quality testing Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Detergent Compositions (AREA)
Abstract
The present invention discloses a formula of antiseptic hand-protecting liquor and its preparation method. It is made up by using benzalkonium bromide cationic active group as main active component and adding other surfactant, conditioner and adjuvant as auxiliary components through a certain preparation process. Said antiseptic hand-protecting liquor has three functions of killing bacterial, cleaning skin and moistening skin.
Description
One, technical field:
The present invention relates to a kind of preparation method with disposable foam type antibiotic hand-care liquid of sterilization, cleaning and the three-in-one function of skin moistening.
Two, background technology:
Along with reform deeply and the developing by leaps and bounds of national economy, people's economic activity contacts are frequent, the frequency of amusement and travel is also more and more higher, and is bright from the medical science data sheet, a lot of its routes of transmission of pathogenic bacterium mainly contact with pathogen with air and on infected.Thereby at first avoid colliding the article that polluted in outdoor activity, contacts and the amusement and travel process, priorly to accomplish the duty sterilization of washing one's hands, stop because of the hands contact infected.The kind of the handwashing liquid of the usefulness of washing one's hands, handguard liquid is many, but this series products on the market mainly is based on decontamination, and some bottle sticks and indicates antibiotic, bacteriostasis, and being actually does not have or effect seldom.To the quality testing of Shanghai commercial anti (pressing down) bacterium lotion, the antibacterial qualification rate is 53.1% as a result, antibacterial class lotion 46.9% according to Chinese Disinfection magazine (2006.1 phase) report.Report from existing patent documentation, some liquid handwashing liquid of having developed have defective in various degree.
The CN1112157A skin care hand cleaning liquid is with the handwashing liquid of alkylol polyoxyethylene ether, betanin, alkylol polyoxyethylene ether sulfuric acid ester potassium, glycerol, ethanol preparation, with 1-3 times of double as leave of 10-90% ethanol dilution handwashing liquid, contain so many alcohols handwashing liquid, can cause stimulation skin and mucosa; This antibacterial of patent of invention ZL02126050.8 is formulated by chlorhexidine acetate, benzalkonium bromide, glycerol etc., although the obvious sterilization effect is arranged, but contain glycerol, skin had stimulation, the product that other enterprise produced, example, the patent EP0843002 foam type desinfactant detergent of Japanese Kao company, it is to be master's active ingredient by benzalkonium chloride, hibitane; The patent JP11263995 of Japan Shiseido company is the good detergent of clean skin bactericidal effect, and it is to be main active ingredient by benzalkonium chloride, trichlorine to hexichol, hibitane, and shown production cost is higher relatively.
Three, summary of the invention
The objective of the invention is to overcome above-mentioned defective, what a kind of alcohol-free composition was provided is main active ingredient with benzalkonium bromide, and sterilizing rate moment can reach more than 99.9%, has the preparation method of the leave antibiotic hand-care liquid of sterilization, cleaning and skin moistening three big functions.The present invention is achieved by following technical proposals: it is characterized in that: its prescription (by weight percentage) is to form with following component:
Benzalkonium bromide 0.1-0.2%
Surfactant 1-10%
Conditioner 0.1-1%
Auxiliary agent 0.5-5%
Adjuvant 0.5-2%
All the other are deionized water.
Above raw material is commercially available;
Its preparation method: take by weighing each component: benzalkonium bromide is water-soluble by prescription, stir, add surfactant, conditioner more successively, after adding the water stirring again, after adding the stirring of PCMX antiseptic and allantoin again, solution is heated to 70-80 ℃ is stirred to dissolving fully, cool off Yi Bian place.Get and be dissolved in water again after another container takes by weighing citric acid and HPMC mixing, get a container again and add the minimal amounts of dissolved triethanolamine, the aqueous solution of another container is poured in the container of benzalkonium bromide and gone, ceaselessly stir until complete mix homogeneously, survey pH value, add triethanolamine solution then as one feels fit and adjust PH=5.5-6.5, solution is cooled to add below 35 ℃ flavouring agent and coloring agent in the molten device, cool to room temperature gets final product fill; Described conditioner is two or more in dimethyl dodecyl amine oxide, cocamidopropyl propyl amide amine oxide, the CH3-(CH2)13N(CH3)2-O; Described auxiliary agent is an allantoin.Described auxiliary agent also comprises triethanolamine and hydroxypropyl emthylcellulose (HPMC).Described auxiliary agent is PCMX (4-chloro-3,5-diformazan atmosphere) efficient antiseptic and compound preservative GMP-1 (by diazonium alkyl imidazoline urine, the mixture aqueous solution of third fat, propylene glycol preparation).Described adjuvant also comprises citric acid, flavouring agent and food coloring.Described surfactant be in dodecyldimethylammonium hydroxide inner salt, hexadecyltrimethylammonium chloride, lauryl imidazolinium betaine, the cocamido propyl betaine more than three kinds or three kinds;
The foam type antibiotic hand-care liquid that the present invention makes has sterilization, cleaning, skin protection three big functions, mainly is to be given by surfactant, conditioner, auxiliary agent and main active ingredient in the prescription, is summarized as follows:
Benzalkonium bromide is dissociated into the cation activity group in aqueous solution, this product has sterilization and detergent power concurrently, and effect is strong and fast.Be widely used in aspects such as sterilization, sterilization, anticorrosion, de-sludging, stable in properties is easy to preserve, free from environmental pollution.
Surfactant in the prescription mainly is two property ionic surface active agents, good with other surfactant compatibility, stable in more extensive PH scope, zest to eyes, skin is little, and have washing, detergency ability, antistatic and bactericidal action, flexibility is good, and foaminess is good, and safety non-toxic, biological degradability are also fine.
The dodecayl dimethyl amine oxide that conditioner in the prescription is selected for use etc. belong to weak ionic surface active agent, and scourability is good, and foam is many and stablize; the gentle performance that stimulates of character is low; and having good flexibility, can be used as foam enhancing and move infusion, is effective skin smoothing, emollient; nontoxic, biological degradability good; need not the water flushing after the use, safe in utilization, convenient, nontoxic, nonirritant (soft composition) has protection skin; the feel exquisiteness, sterilization and detergency are strong.And effect is fast, and moment is removed antibacterial rate 〉=99.9%, it is behind people ante cibum, the lavatory, at home tourism carry, cheap a kind of new product.
Four, the specific embodiment:
Be example below, the present invention be further described with 2 embodiment:
Its prescription (by weight percentage) is to form with following component:
Benzalkonium bromide 0.15%
Dimethyl dodecyl amine oxide 1%
Dodecyldimethylammonium hydroxide inner salt 0.6%
Lauryl imidazolinium betaine 0.4%
Cocamidopropyl propyl amide amine oxide 0.1%
Dimethyl dodecyl amine oxide 0.1%
PCMX antiseptic 1% or alternative with compound preservative GMP-1;
Allantoin 0.1%
Citric acid 0.05%
Hydroxypropyl emthylcellulose (HPMC) 0.05%
Deionized water 96.45%.
Embodiment 1:
Take by weighing each component by formula ratio, at first benzalkonium bromide is dissolved in the deionized water in first container, after stirring, add dodecyldimethylammonium hydroxide inner salt, hexadecyltrimethylammonium chloride, lauryl imidazolinium betaine, dimethyl dodecyl amine oxide, cocamidopropyl propyl amide amine oxide successively, a kind of component of every adding all will ceaselessly stir, add the PCMX antiseptic again, after stirring, add allantoin successively, then this container is warmed to 70-80 ℃, stirs the back and place cooling.
Get second container and take by weighing citric acid and HPMC, behind the two mix homogeneously, add the small amount of deionized water dissolving again, be stirred to dissolving fully.
Get the 3rd container and take by weighing triethanolamine, add the low amounts of water dissolving, stir.Solution in second container is poured in first container, strengthened being stirred to and fully evenly survey pH value, add triethanolamine solution then as one feels fit and adjust pH value 5.5-6.5.Cool off while stirring, when solution is cooled to below 35 ℃, add flavouring agent and coloring agent, stir, be cooled to room temperature, fill gets final product.
Embodiment 2:
The benzalkonium bromide of formula ratio is dissolved in the aqueous solution of compound preservative GMP-1 and allantoin, be stirred to dissolving fully, add dodecyldimethylammonium hydroxide inner salt more successively, cocamido propyl betaine, the lauryl imidazolinium betaine, dimethyl dodecyl amine oxide, CH3-(CH2)13N(CH3)2-O, when adding each component again, need constantly stir, until evenly, add another kind of component again, the low amounts of water dissolving will be added behind HPMC and the citric acid mix homogeneously, stir the back fully evenly, pour into then in the above-mentioned lysate, mix, add the triethanolamine aqueous solution again and adjust PH=5.5-6.5.Add flavouring agent and food coloring coloring agent, after stirring, after static a few hours, fill gets final product.
Claims (3)
1. the preparation method of an antibiotic hand-care liquid is characterized in that step is as follows:
1), take by weighing each component by following prescription and percentage by weight:
Benzalkonium bromide 0.1-0.2%
Surfactant 1-10%
Conditioner 0.1-1%
Auxiliary agent 0.5-5%
Adjuvant 0.5-2%
All the other are deionized water,
Wherein, described surfactant is at least three kinds in dodecyldimethylammonium hydroxide inner salt, hexadecyltrimethylammonium chloride, lauryl imidazolinium betaine, the cocamido propyl betaine, described conditioner is at least two kinds in dimethyl dodecyl amine oxide, cocamidopropyl propyl amide amine oxide, the CH3-(CH2)13N(CH3)2-O, described auxiliary agent is allantoin, triethanolamine and hydroxypropyl emthylcellulose, and described adjuvant is citric acid, flavouring agent and coloring agent and PCMX antiseptic or GMP-1 antiseptic;
2), benzalkonium bromide is dissolved in the deionized water of first container, stir, add described surfactant and conditioner more successively, after adding the water stirring, after adding the stirring of described antiseptic and allantoin again, solution in first container is heated to 70-80 ℃, is stirred to dissolving fully, place cooling;
Get second container and take by weighing citric acid and hydroxypropyl emthylcellulose, be dissolved in water again behind the mixing;
Get the 3rd container triethanolamine that is dissolved in water, solution in second container is poured in the solution of first container, ceaselessly stir until mix homogeneously, survey pH value, the triethanolamine solution that adds again in the solution of first container in the 3rd container is adjusted pH value to 5.5-6.5, treats that the solution in first container is cooled to below 35 ℃, adds flavouring agent and coloring agent, cool to room temperature obtains the antibiotic hand-care liquid finished product.
2. press the preparation method of the described antibiotic hand-care liquid of claim 1, it is characterized in that step 2) in, the described surfactant that adds in first container is dodecyldimethylammonium hydroxide inner salt, hexadecyltrimethylammonium chloride and lauryl imidazolinium betaine, the described conditioner that adds is dimethyl dodecyl amine oxide and cocamidopropyl propyl amide amine oxide, and the described antiseptic of adding is the PCMX antiseptic.
3. by preparation method by the described antibiotic hand-care liquid of claim 1, it is characterized in that step 2) in, the described surfactant that adds in first container is dodecyldimethylammonium hydroxide inner salt, cocamido propyl betaine and lauryl imidazolinium betaine, the described conditioner that adds is dimethyl dodecyl amine oxide and CH3-(CH2)13N(CH3)2-O, and the described antiseptic of adding is the GMP-1 antiseptic.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2006100286358A CN101099714B (en) | 2006-07-06 | 2006-07-06 | Antibiotic hand-care liquid preparing method |
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|---|---|---|---|
| CN2006100286358A CN101099714B (en) | 2006-07-06 | 2006-07-06 | Antibiotic hand-care liquid preparing method |
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| CN101099714B true CN101099714B (en) | 2010-12-08 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111065721A (en) * | 2017-10-30 | 2020-04-24 | 花王株式会社 | Bactericidal detergent composition |
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| HUE032612T2 (en) * | 2011-06-24 | 2017-10-30 | Sca Tissue France | Personal cleaning composition comprising gelling and foaming agents for tissue impregnation |
| CN103767894A (en) * | 2012-10-25 | 2014-05-07 | 阳紫威 | Anti-bacteria hand-washing solution |
| CN103725443A (en) * | 2013-12-10 | 2014-04-16 | 芜湖华海生物工程有限公司 | Allantoin-containing sterilization and skin-protection traditional Chinese medicine washing-up liquid |
| CN105832573A (en) * | 2016-04-19 | 2016-08-10 | 南京巨鲨显示科技有限公司 | Amine antibacterial liquid soap |
| WO2019126703A1 (en) | 2017-12-22 | 2019-06-27 | Ecolab Usa Inc. | Antimicrobial compositions with enhanced efficacy |
| CN108125860A (en) * | 2018-01-17 | 2018-06-08 | 上海茂久中医药科技有限公司 | A kind of formula of white flower loropetalum chinense sterilizing article |
| CN110859811B (en) * | 2019-12-05 | 2021-12-07 | 北京博恩特药业有限公司 | Medicine slow-release composition and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111065721A (en) * | 2017-10-30 | 2020-04-24 | 花王株式会社 | Bactericidal detergent composition |
| CN111065721B (en) * | 2017-10-30 | 2021-10-26 | 花王株式会社 | Bactericidal detergent composition |
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| CN101099714A (en) | 2008-01-09 |
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Effective date of registration: 20240605 Address after: Building 5, No. 95 Xiasha New Street, Hangtou Town, Pudong New Area, Shanghai, 201317 Patentee after: Shanghai Zhongying Health and Green Enterprise Development Co.,Ltd. Country or region after: China Address before: Xiangyang Road, Xinchang Town Shanghai City, No. 32, 201314 Patentee before: SHANGHAI WEILI DISINFECTANT Co.,Ltd. Country or region before: China |
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Correction item: transfer of patent right Correct: Shanghai Zhongyingjian Green Enterprise Development Co.,Ltd. False: Shanghai Zhongying Health and Green Enterprise Development Co.,Ltd. Number: 25-01 Volume: 40 |
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