CN107007515A - A kind of women secret conditioning liquid and preparation method thereof - Google Patents
A kind of women secret conditioning liquid and preparation method thereof Download PDFInfo
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- CN107007515A CN107007515A CN201710443014.4A CN201710443014A CN107007515A CN 107007515 A CN107007515 A CN 107007515A CN 201710443014 A CN201710443014 A CN 201710443014A CN 107007515 A CN107007515 A CN 107007515A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
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- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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Abstract
The invention discloses a kind of women secret conditioning liquid, including following components in percentage by weight:Cationic thickener 0.1% 1%, NMF 1% 20%, surfactant 1% 20%, functional component 1% 30%, acidity-basicity regulator 0.1% 1%, surplus is purified water.Preparation method, comprises the following steps:(1)Cationic thickener, plus purified water stirring are weighed, homogeneous liquid is formed;(2)NMF, surfactant and functional component are added into homogeneous liquid, is stirred;(3)To step(2)Acidity-basicity regulator is added in gains, its pH value of solution is adjusted to 45.Cationic thickener of the present invention, surfactant, functional component and NMF are combined, and synergy is played in terms of restraining and sterilizing bacteria;Functional component and acidity-basicity regulator can synergic adjustment its conditioning liquid acid-base value, and then suppress harmful bacteria protection probiotics.
Description
Technical field
The invention belongs to female private part sanitary care article technical field, and in particular to a kind of women secret conditioning liquid and its
Preparation method.
Background technology
Female private part vagina is an open cavity, is the important Tiny ecosystem area of women, its construct it is sufficiently complex and
Sensitivity, body has visibly different change the every month as private parts vagina without other organs.The cuticula ratio of private parts
It is relatively thin, but crinite protection, in addition to general sweat gland, there are many special sebum bodies of gland, dimension under the hair of private parts
Hold the acid-base value and lubricity of genital skin.These bodies of gland can also secrete sweat, but different from general sweat gland, they are first
Then accumulation secretion be secreted again in body of gland, and can change with the menstrual cycle, menstruation come before secrete compared with
To be vigorous, so being just easier to produce infection or long acne, situation is serious in the event of blocking in this period, in some instances it may even be possible to
Cause abscess.Private parts is acid environment with vagina environment, and pH value is about 4, and intravaginal has many Bacillus acidi lacticis remaining cloudy
The health of road environment, number is all seldom at nominal conditions for other bacteriums, mould, if external interference or cause of disease enter
Invade, be likely to result in the infection of germ hyperplasia, cause vulvovaginal uncomfortable or even produce gynecological disease.
The problem of nursing due to some notional errors and not in time, private parts such as vulvovaginal itching, peculiar smell, secretion
Thing, which increases, swollen and ache etc., usually annoyings female friend.Therefore, the maintenance of the health maintenance of women, especially female private part with it is clear
It is clean more and more to be paid attention to by modern female.In the daily nursing of female private part, feminine wash is protected as numerous women secrets
The first choice of product is managed, about 45% women selection alleviates privates discomfort and auxiliary treatment gynaecological imflammation using feminine wash.It is existing
Lotion product is generally Chinese herbal and crude drugs preparations or traditional Chinese medicine mix preparation, by largely using clearing heat and detoxicating Chinese medicine come restraining and sterilizing bacteria or
Person's collocation antibiotic, bactericide thoroughly rapidly to kill bacterium.But, often effect is slow for pure Chinese herbal medicine washing lotion, simply
It is clearing heat and detoxicating, the destruction of reverse side can be caused to female reproductive system.And the product of bactericide or antibiotic is added, though effect is fast,
But side effect is larger, commonly using can destroy environment in female genital tract, or even drug resistance is produced.
The content of the invention
For above-mentioned deficiency of the prior art, the invention provides a kind of women secret conditioning liquid and preparation method thereof,
It can effectively solve that lotion product effect of the prior art is slow or side effect big, what female reproductive system was damaged asks
Topic.
To achieve the above object, the technical solution adopted for the present invention to solve the technical problems is:
A kind of women secret conditioning liquid, including following components in percentage by weight:Cationic thickener 0.1%-1%, NMF 1%-
20%th, surfactant 1%-20%, functional component 1%-30%, acidity-basicity regulator 0.1%-1%, surplus is purified water;
Wherein, functional component be niacinamide, alpha-glucans oligosaccharides, perilla leaf extract, collargol, smilax root extract,
In skin berry extract, cnidium monnieri berry extract, kuh-seng root extract, A. gigas root extract and grape Fructus Citri grandis extract at least
It is a kind of.
A kind of women secret conditioning liquid, including following components in percentage by weight:Cationic thickener 0.2%, NMF
10%th, surfactant 7%, functional component 18%, acidity-basicity regulator 0.5%, surplus is purified water.
Further, cationic thickener is chitosan, carboxymethyl chitin sodium salt or sylvite, carboxymethyl chitosan
At least one of sugared sodium salt or sylvite, guar gum and polyacrylamide.
Further, NMF is propane diols, glycerine, polyethylene glycol 200, polyethylene glycol 400, butanediol and glycine betaine
At least one of in.
Further, surfactant is lauryl glucoside, soapberry extract, Cocoamidopropyl betaine, told
At least one of temperature, ethoxylated dodecyl alcohol sodium sulphate and sodium cocoyl glycinate.
Further, acidity-basicity regulator be lactic acid, sodium lactate, triethanolamine, citric acid and sodium citrate at least
It is a kind of.
The preparation method of above-mentioned women secret conditioning liquid, comprises the following steps:
(1)Cationic thickener, plus purified water stirring are weighed, homogeneous liquid is formed;
(2)NMF, surfactant and functional component are added into homogeneous liquid, is stirred;
(3)To step(2)Acidity-basicity regulator is added in gains, its pH value of solution is adjusted to 4-5.
A kind of women secret conditioning liquid that the present invention is provided and preparation method thereof, has the advantages that:
(1)Cationic thickener has good biocompatibility, adhesion, degradability, biocidal property and plasticity, can promote wound
Mouth healing and regeneration.
Surfactant, green safety and the effect with bactericidal, from following several materials, between its each composition
By synergy, the mildness of product can be improved, increase its wetability, played while can also be combined with cationic thickener
Thickening power, is combined with functional component and plays restraining and sterilizing bacteria effect, such as:
The nonionic surfactant that lauryl glucoside is made up of renewable plant material, can be with various ionics, nonionic
Type surfactant compound produces synergistic effect, and can significantly improve the mildness of product of the present invention.
Soapberry extract, containing abundant glycoside material, with very strong surface-active action, be it is natural it is non-from
Subtype surfactant, has effects that antibacterial, sterilization and anti-inflammatory;Soapberry also contains many materials beneficial to human body, such as
Reduced sugar, aliphatic acid, grease, oleic acid, carotenoid, riboflavin, protein, vitamin C, vitamin A, vitamin B and bad ammonia
The several amino acids of acid, tyrosine, phenylalanine, glutamic acid, glycine and histidine etc. 10, have opsonic action to human body.
Cocoamidopropyl betaine, is a kind of zwitterionic surfactant, uniform under acid and alkalescence condition
Excellent stability, presentation male and female is ionic respectively, is often used in combination with anions and canons and nonionic surfactant, and it is stimulated
It is small, it is soluble in water, to ph stability, with excellent thickening property, flexibility, bactericidal properties.
Tween, is nonionic surface active agent, nontoxic, non-stimulated, and has bacteriostasis.
Lauryl glucoside, is nonionic surface active agent, nontoxic, non-stimulated, soluble in water, with other surfaces activity
Agent is compounded, and substantially, thickening effect is notable, acid-fast alkali-proof for synergy, and with restraining and sterilizing bacteria effect.
Functional component has effects that deodorization, antipruritic, bactericidal, maintains acid-base balance, such as:
Niacinamide, can quickly pass through cuticula, improve the barrier action of skin, improve the resistance of skin, reduce its dehydration
Rate, so as to protect the growth of probiotics at women secret.
Alpha-glucans oligosaccharides, can promote the growth of probiotics at women secret, have inhibitory action to pathogenic bacteria.
Perilla leaf extract, containing multivitamin, mineral matter, also containing perillaldehyde, eugenol, Soviet Union's ketenes, perilla alcohol,
The various bioactivators such as limonene, citral, Polyphenols;Containing big in plant polyphenol and flavone compound molecular structure
The phenolic hydroxyl group of amount, these phenolic hydroxyl groups can act on the ultrastructure of microorganism, to staphylococcus aureus, Escherichia coli,
Pseudomonas aeruginosa is inhibited.
Collargol, with excellent antibacterial and deodouring effect, and is easier to be absorbed by and excretes, and can effectively suppress single
The bacterium of one cell, the growth of viral and fungi, are respectively provided with good inhibitory action, its nontoxic nothing to bacterium, virus and fungi
Taste has no side effect, harmless to human body cell without free radical, compared with antibiotic and bactericide, and maximum advantage is not produce
Drug resistance.
Smilax root extract, containing materials such as saponin(e, tannins, the saponin(e has antibacterial, antipyretic activity;Tannin has
Stronger reproducibility, can remove the superoxide radical in organism, anti-aging, the additionally effect with anti-bacteria and anti-virus.
Summer cypress berry extract, containing a large number of nutrients protein, carbohydrate, electrolytes and minerals outside, also
With bacteriostasis, pruitus can be treated.
Common cnidium fruit P.E, with bacteriostasis, available for preventing and treating female vulva itch, vaginitis, but is used alone, effect
Fruit is not good, is used together with the formula of other in this programme, effect is obvious.
Kuh-seng root extract, with heat-clearing and damp-drying drug, the antipruritic effect of desinsection has to alleviate well to pruitus and made
With it combines summer cypress berry extract and common cnidium fruit P.E is combined, and has obvious work(well in terms of pruitus is treated
Effect.
A. gigas extract, the effect with improvement skin microcirculation promoting blood circulation and removing blood stasis, its SOD sample activity is stronger, can press down
Caused by superoxide radical processed membrane lipid peroxidatio reaction and radical reaction, and with biological film phospholipid join protection membrane lipid
Etc. infringement of the antagonism free radical to tissue is carried out, it is combined with smilax root extract, can remove internal superoxide radical, is delayed
Aging.
Grape Fructus Citri grandis extract, can nurse tissue cell, effect of antibacterial anti-infection can be with other of the invention functional components
It is used in combination, plays a part of restraining and sterilizing bacteria.
Above-mentioned functional component, which is combined, can treat pruitus, play a part of restraining and sterilizing bacteria, while can also remove body
Interior superoxide radical, anti-aging.
Cationic thickener, surfactant, functional component and NMF are combined, and collaboration is played in terms of restraining and sterilizing bacteria
Effect.
Functional component and acidity-basicity regulator can synergic adjustment its conditioning liquid acid-base value, make itself and female private part acid-base value
It is consistent.
(2)The present invention is by specific recipe ingredient, and the product prepared has restraining and sterilizing bacteria effect to harmful bacteria, and to benefit
Raw bacterium can play a part of protection, and it is free of antibiotic, bactericide and preservative, and drug resistance will not be produced after human body use.
Embodiment
Embodiment 1
A kind of women secret conditioning liquid, including following components in percentage by weight:Chitosan 0.1%, lactic acid 0.4%, third
Glycol 3%, glycerine 3%, polyethylene glycol 400 3%, glycine betaine 1%, niacinamide 2%, collargol 0.5%, summer cypress berry extract 1%, snake
Machine tool extract 3%, kuh-seng root extract 3%, A. gigas extract 1%, grape Fructus Citri grandis extract 1%, soapberry extract 2%,
Cocoamidopropyl betaine 10%, polysorbas20 1%, surplus is ultra-pure water.
The preparation method of above-mentioned women secret conditioning liquid, comprises the following steps:
(1)Ultra-pure water is heated to 100 DEG C, placement certain time makes its temperature be down to less than 40 DEG C, then that deacetylated shell is more
Sugar is added in purified water and stirred, and forms homogeneous liquid;
(2)Propane diols, glycerine, polyethylene glycol 400, glycine betaine, soapberry extract, cocounut oil are sequentially added into homogeneous liquid
Amido propyl betaine, polysorbas20, niacinamide, collargol, summer cypress berry extract, common cnidium fruit P.E, kuh-seng root extract, court
Fresh Radix Angelicae Sinensis extract and grape Fructus Citri grandis extract, often add and 20min are stirred after a kind of material, and mixing speed is 400r/min;
(3)To step(2)Lactic acid is added in gains, its pH value of solution is adjusted to 4-5.
The application method of above-mentioned women secret conditioning liquid is:Clean after hand, take appropriate women secret conditioning liquid to be applied to private
After Mi Chu, soft 1-2min, rinsed well with clear water.
Embodiment 2
A kind of women secret conditioning liquid, including following components in percentage by weight:Chitosan 0.1%, citric acid 0.1%,
Lactic acid 0.2%, propane diols 3%, glycerine 3%, polyethylene glycol 400 3%, glycine betaine 1%, lauryl glucoside 5%, coconut oleoyl amine third
Base glycine betaine 8%, niacinamide 2%, alpha-glucans oligosaccharides 2%, perilla leaf extract 3%, summer cypress berry extract 1%, common cnidium fruit P.E
3%th, kuh-seng root extract 3%, A. gigas extract 1%, grape Fructus Citri grandis extract 1%, surplus is ultra-pure water.
The preparation method of above-mentioned women secret conditioning liquid, comprises the following steps:
(1)Ultra-pure water is heated to 100 DEG C, placement certain time makes its temperature be down to less than 40 DEG C, then that deacetylated shell is more
Sugar is added in purified water and stirred, and forms homogeneous liquid;
(2)Propane diols, glycerine, polyethylene glycol 400, glycine betaine, lauryl glucoside, cocounut oil are sequentially added into homogeneous liquid
Amido propyl betaine, niacinamide, alpha-glucans oligosaccharides, perilla leaf extract, summer cypress berry extract, common cnidium fruit P.E, hardship
Join root extract, A. gigas extract and grape Fructus Citri grandis extract, often add and 20min, mixing speed are stirred after a kind of material
For 400r/min;
(3)To step(2)Lactic acid and citric acid are added in gains, its pH value of solution is adjusted to 4-5.
The application method of above-mentioned women secret conditioning liquid is:Clean after hand, take appropriate women secret conditioning liquid to be applied to private
After Mi Chu, soft 1-2min, rinsed well with clear water.
Embodiment 3
A kind of women secret conditioning liquid, including following components in percentage by weight:Chitosan 0.2%, lactic acid 0.5%, third
Glycol 3%, glycerine 3%, polyethylene glycol 400 3%, glycine betaine 1%, soapberry extract 2%, Cocoamidopropyl betaine 10%,
Polysorbas20 1%, niacinamide 2%, alpha-glucans oligosaccharides 2%, perilla leaf extract 3%, smilax root extract 2%, summer cypress fruit are extracted
Thing 1%, common cnidium fruit P.E 3%, kuh-seng root extract 3%, A. gigas extract 1%, grape Fructus Citri grandis extract 1%, surplus is
Ultra-pure water.
The preparation method of above-mentioned women secret conditioning liquid, comprises the following steps:
(1)Ultra-pure water is heated to 100 DEG C, placement certain time makes its temperature be down to less than 40 DEG C, then that deacetylated shell is more
Sugar is added in purified water and stirred, and forms homogeneous liquid;
(2)Propane diols, glycerine, polyethylene glycol 400, glycine betaine, soapberry extract, cocounut oil are sequentially added into homogeneous liquid
Amido propyl betaine, polysorbas20, niacinamide, alpha-glucans oligosaccharides, perilla leaf extract, smilax root extract, summer cypress fruit
Extract, common cnidium fruit P.E, kuh-seng root extract, A. gigas extract and grape Fructus Citri grandis extract, often add a kind of thing
20min is stirred after matter, mixing speed is 400r/min;
(3)To step(2)Lactic acid is added in gains, its pH value of solution is adjusted to 4-5.
The application method of above-mentioned women secret conditioning liquid is:Clean after hand, take appropriate women secret conditioning liquid to be applied to private
After Mi Chu, soft 1-2min, rinsed well with clear water.
Bacteriostatic experiment of the conditioning liquid of experimental example 1 to pathogenic bacteria
Object:The secret conditioning liquid prepared from Candida albicans testing example 1-3 is to the inhibitions of pathogenic bacteria.
Vaccination ways:Candida albicans is inoculated with using test tube.
Experiment packet:This experimental example sets blank group, positive controls, physiological saline group and treatment group, treatment group difference
Using the product prepared by embodiment 1, embodiment 2 and embodiment 3.
Blank control group:Only 15ml sabouraud culture mediums.
Positive controls:It is 1 × 10 to take bacterial strain quantity3White chain pearl bacterium 0.5ml be inoculated in 15ml sabouraud culture mediums,
In 37 DEG C, 48h is cultivated under the conditions of 220r/min.
Physiological saline group:It is 1 × 10 to take bacterial strain quantity3White chain pearl bacterium 0.5ml be inoculated in 15ml sabouraud culture mediums,
Then 0.5ml physiological saline is added, in 37 DEG C, 48h is cultivated under the conditions of 220r/min.
Treatment group:It is 1 × 10 to take bacterial strain quantity3White chain pearl bacterium 0.5ml be inoculated in 15ml sabouraud culture mediums, then
0.5ml products of the present invention are added, in 37 DEG C, 48h is cultivated under the conditions of 220r/min.
Experimental result:With not plus compared with the positive controls of secret conditioning liquid, the nutrient solution transparency for the treatment of group is limpid
It is transparent, and positive controls are white opacity liquid.Treatment group transparency and blank control group, physiological saline group are consistent, and display adds
Plus after secret conditioning liquid, the growth of white chain pearl bacterium is totally constrained.
Experimental example 2
Object:Influence of the secret conditioning liquid to probiotics prepared from Lactobacillus acidophilus testing example 1-3.
Vaccination ways:Lactobacillus acidophilus is inoculated with using test tube.
Experiment packet:This experimental example sets blank group, positive controls, physiological saline group and treatment group, treatment group difference
Using the product prepared by embodiment 1, embodiment 2 and embodiment 3.
Blank control group:Only 15ml MRS culture mediums.
Positive controls:It is 1 × 10 to take bacterial strain quantity5Lactobacillus acidophilus 0.5ml be inoculated in 15ml MRS culture mediums,
In 37 DEG C, 24h is cultivated under the conditions of 220r/min.
Physiological saline group:It is 1 × 10 to take bacterial strain quantity5Lactobacillus acidophilus 0.5ml be inoculated in 15ml MRS culture mediums,
Then 0.5ml physiological saline is added, in 37 DEG C, 24h is cultivated under the conditions of 220r/min.
Treatment group:It is 1 × 10 to take bacterial strain quantity5Lactobacillus acidophilus 0.5ml be inoculated in 15ml sabouraud culture mediums, then
0.5ml products of the present invention are added, in 37 DEG C, 48h is cultivated under the conditions of 220r/min.
Experimental result:With not plus compared with the positive controls of secret conditioning liquid, adding the training of the treatment group of secret conditioning liquid
Nutrient solution turbidity is consistent with positive controls, is faint yellow turbid solution.Blank control group, physiological saline group are as clear as crystal liquid
Body.As a result show, the growth of probiotics is not suppressed because of addition secret conditioning liquid, in other words, secret conditioning liquid
There are product best results prepared by protective effect, especially embodiment 3 to the growth of probiotics.
Claims (7)
1. a kind of women secret conditioning liquid, it is characterised in that including following components in percentage by weight:Cationic thickener
0.1%-1%, NMF 1.0%-20%, surfactant 1.0%-20%, functional component 1%-30%, acidity-basicity regulator 0.1%-1%,
Surplus is purified water;
Wherein, functional component be niacinamide, alpha-glucans oligosaccharides, perilla leaf extract, collargol, smilax root extract,
In skin berry extract, cnidium monnieri berry extract, kuh-seng root extract, A. gigas root extract and grape Fructus Citri grandis extract at least
It is a kind of.
2. women secret conditioning liquid according to claim 1, it is characterised in that including following components in percentage by weight:
Cationic thickener 0.2%, NMF 10%, surfactant 7%, functional component 18%, acidity-basicity regulator 0.5%, surplus are pure
Change water.
3. women secret conditioning liquid according to claim 1 or 2, it is characterised in that cationic thickener is deacetylated shell
In polysaccharide, carboxymethyl chitin sodium salt or sylvite, carboxymethyl chitosan sodium salt or sylvite, guar gum and polyacrylamide at least
It is a kind of.
4. women secret conditioning liquid according to claim 1 or 2, it is characterised in that NMF be propane diols, glycerine,
At least one of in polyethylene glycol 200, polyethylene glycol 400, butanediol and glycine betaine.
5. women secret conditioning liquid according to claim 1 or 2, it is characterised in that surfactant is lauryl glucose
Glycosides, soapberry extract, Cocoamidopropyl betaine, tween, ethoxylated dodecyl alcohol sodium sulphate and cocounut oil acyl glycine
At least one of sodium.
6. women secret conditioning liquid according to claim 1 or 2, it is characterised in that acidity-basicity regulator is lactic acid, lactic acid
At least one of sodium, triethanolamine, citric acid and sodium citrate.
7. the preparation method of the women secret conditioning liquid described in claim any one of 1-6, it is characterised in that including following step
Suddenly:
(1)Cationic thickener, plus purified water stirring are weighed, homogeneous liquid is formed;
(2)NMF, surfactant and functional component are added into homogeneous liquid, is stirred;
(3)To step(2)Acidity-basicity regulator is added in gains, its pH value of solution is adjusted to 4-5.
Priority Applications (1)
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CN109106806A (en) * | 2018-06-20 | 2019-01-01 | 广州宏韵医药科技股份有限公司 | A kind of women secret nursing washing lotion and preparation method thereof |
CN109260124A (en) * | 2018-11-30 | 2019-01-25 | 成都珂萝瑞诗化妆品有限公司 | A kind of women secret nursing lubricating fluid and preparation method thereof |
CN109568206A (en) * | 2018-12-26 | 2019-04-05 | 株洲千金药业股份有限公司 | A kind of bacteria inhibiting composition being exclusively used in women and washing lotion and preparation method |
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CN112022745A (en) * | 2020-09-09 | 2020-12-04 | 湖南小黄巾卫生用品有限公司 | Female private part nursing wet tissue containing prebiotic ecological nutrient solution |
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CN109106806A (en) * | 2018-06-20 | 2019-01-01 | 广州宏韵医药科技股份有限公司 | A kind of women secret nursing washing lotion and preparation method thereof |
CN109260124A (en) * | 2018-11-30 | 2019-01-25 | 成都珂萝瑞诗化妆品有限公司 | A kind of women secret nursing lubricating fluid and preparation method thereof |
CN109568206A (en) * | 2018-12-26 | 2019-04-05 | 株洲千金药业股份有限公司 | A kind of bacteria inhibiting composition being exclusively used in women and washing lotion and preparation method |
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CN112220728A (en) * | 2020-11-12 | 2021-01-15 | 河南美凝生物科技有限公司 | Gynecological cleaning fluid with antibacterial and prebiotics maintenance functions and preparation method thereof |
CN112220737A (en) * | 2020-11-24 | 2021-01-15 | 广州市拓瑞科技有限公司 | Female private nursing gel and preparation method thereof |
CN112999290A (en) * | 2021-03-25 | 2021-06-22 | 亚美利加(辽宁)药业有限公司 | Multifunctional private repair care solution |
CN113332210A (en) * | 2021-06-16 | 2021-09-03 | 广东快女生物技术有限公司 | Formula of composite traditional Chinese medicine female private film for deep nursing |
CN114344192A (en) * | 2022-01-24 | 2022-04-15 | 耀然实业股份有限公司 | Personal care composition, personal care product and personal care product |
CN116898901A (en) * | 2023-08-14 | 2023-10-20 | 陕西科技大学 | External genitalia nursing spray and preparation method thereof |
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