CN104399017A - Composition for prevention and treatment of female vulva inflammation - Google Patents
Composition for prevention and treatment of female vulva inflammation Download PDFInfo
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- CN104399017A CN104399017A CN201410578939.6A CN201410578939A CN104399017A CN 104399017 A CN104399017 A CN 104399017A CN 201410578939 A CN201410578939 A CN 201410578939A CN 104399017 A CN104399017 A CN 104399017A
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- 0 COCC([C@@](CC1)[C@@]1(C(*1(CC2)O)O)OCC(*C(*)*3O)OC(C*)C3O)[C@@]12O Chemical compound COCC([C@@](CC1)[C@@]1(C(*1(CC2)O)O)OCC(*C(*)*3O)OC(C*)C3O)[C@@]12O 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Medicines Containing Plant Substances (AREA)
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Abstract
The invention aims to provide a ''composition'' for prevention and treatment of female vulva inflammation. The composition is prepared precisely from an EM probiotic stock solution, marine ferment, ginger ferment, allicin, pineapple ferment, trehalose, lactic acid, and mineral nutrients as the raw materials. By protecting the ecological environment of vulva probiotic groups, and by means of the bacteria balancing effect, the quantity of harmful bacteria can be inhibited, and the toxin and malodor generated by harmful flora can be eliminated. In addition to effective prevention and treatment of female vulva inflammation, the composition also can restore cells, nourish skin and hair. The used raw materials are all food grade and pharmaceutical grade, and the ''composition'' cannot generate drug resistance and toxic and side effects.
Description
Technical field
The present invention relates to " a kind of compositions of preventing and treating female vulva inflammation " and preparation method thereof, belong to control gynecological's episioitis field.
Background technology
Female vulva inflammation also claims vaginitis, and vulvitis is one of modal gynaecopathia, has the women of 70% to suffer from vulvitis in the modern life.Trichomonal vaginitis, multiple vagina such as candidiasis (mycete) property vaginitis, bacterial vaginitis etc. can be divided into again according to the different vulvitises of the cause of disease.
There is the main cause of episioitis:
1, unclean sexual life makes the seminal fluid remaining in vagina change the normal environment of vagina, (vagina home is acid, and pH value is about 4.5, and the pH value of alkaline seminal fluid is greater than 7); Property contact also can propagate trichomonal vaginitis.
2, use soap, showering agent, body lotion wash privates and use antibiotic or Chinese medicine dipping bath improperly improperly, have impact on the balance of flora, also cause vagina PH to change, thus destroy the antibacterial barrier of acid vagina, cause colpitis to occur or recurrent exerbation.
3, urinary tract infection, the side-product of urinary tract infection is " strong ammonia " (pH value is greater than 7), also causes the change of vagina PH value, thus affects the balance of flora.
Like this, pernicious bacteria (as; Candidiasis, mycete, antibacterial, fungus, staphylococcus, streptococcus, escherichia coli, trichomonas vaginitis etc.), more than the profitable strain of vagina, and produce toxin, stench, cause colpitis to occur and recurrent exerbation.
During existing control female vulva inflammation is for oral administration, Western medicine product many employings antibiotic, also the different liquid demibain medicament of multiselect, pudendum painting antimicrobial ointment, antifungal preparation etc. of external, in these oral administration and externallies, Western medicine product serve no small effect when preventing and treating female vulva inflammation and suppression, kill harmful flora, but also have unsatisfactory place, as: produce drug resistance and toxic and side effects; Also suppress when suppression, kill harmful flora, killed vagina profitable strain, also destroy the ecological environment of vagina beneficial flora, cause generation or the recurrent exerbation of colpitis.
Be somebody's turn to do " compositions " for above reason, vagina is recovered and maintains the environment of the growth being beneficial to the growth of vagina beneficial flora and being unfavorable for pernicious bacteria and decomposed by biological oxidation and dispel the toxin and stench etc. that pernicious bacteria produces, with suppression, kill harmful flora, the outbreak of control colpitis or recurrent exerbation.
Summary of the invention
The object of the present invention is to provide " a kind of compositions of preventing and treating female vulva inflammation ", to solve the above-mentioned problems in the prior art, protect the ecological environment of vagina beneficial flora and the normal pH value about 4.5 of vagina with " compositions " of the present invention; And the quantity of anaerobe or other harmful bacteria is suppressed by strain balanced action, make it produce stink, dispel toxin and the stench of pernicious bacteria generation; Outside decapacitation effectively preventing female vulva inflammation, thin race, skin nutrition, hair can also be repaired;
The present composition shows there is following advantage through the application test result of several years:
1, the raw material selected of the present invention, each component is food stage and pharmaceutical grade entirely, meets national regarding safety regulation, can also be used on medicine, food, cosmetics
2, vagina is recovered be conducive to the growth of vagina beneficial flora and is unfavorable for the environment (be greater than 7 by PH, return to about PH4.5) of growth of pernicious bacteria,
3, suppression, kill harmful flora, dispelled stench, the outbreak of control colpitis or recurrent exerbation,
4, drug resistance can not be produced and have no side effect
Another object of the present invention is to provide the manufacture method of above-mentioned " compositions ".
" compositions " of the present invention is made up of following compositions in weight percentage:
EM probiotic bacteria stock solution in above-mentioned " compositions ", optimised quantity 50-60%; Ocean ferment optimised quantity 10-15%; Bromelain optimised quantity 10-15%; Rhizoma Zingiberis Recens (ferment) optimised quantity 8-10%.
" nutrient " is Fe++, Mg++, Zn++ element, all adopts organic salt.
The Main Function of above raw material is:
1, EM probiotic bacteria stock solution
Antiphlogistic antibacterial, enhancing immunity, comprising Candida albicans to multiple pathomycete has suppression or killing action; Good therapeutical effect is had to trichomonal vaginitis.(note: EM bacterium Effective Microorganisms is made up of about 80 kinds of microorganisms, EM bacterium is studied successfully by the ratio of university of Japanese Ryukyu is good according to professor's nineteen sixty-eight, puts goods on the market the eighties.EM bacterium is light and bacterium, lactobacillus, yeast, bacillus cereus, acetic acid bacteria, bacillus bifidus, 10 in the large quasi-microorganism of actinomycetes seven belong to more than 80 and plant a kind of microorganism formulation that microorganism is composited);
2, ocean ferment
The base substance of 18 seed amino acids-formation protein in the ferment of ocean, can promote the reparation of the regeneration of body cell and the impaired rear cell of body, meanwhile, also has very strong Antifungal activities; Zinc-cytothesis and protective factors in the ferment of ocean, can accelerate the healing of some ulcer wound; Selenium in the ferment of ocean-can improve SOD activity, reduces the probability of free radical attack cells; Germanium-scavenging free radicals in the ferment of ocean, keeps cytoactive effect.
3, Rhizoma Zingiberis Recens ferment
Rhizoma Zingiberis Recens ferment English name ENZYME, also known as comprehensive plant organized enzyme.There is the effect of detoxicating, killing bacteria and kill effect of trichomonas vaginitis.
4, garlicin
Be somebody's turn to do " garlicin " another name in " compositions ": allicin, allicin; Chemical name: GIUCOSinoate CH2=CH-CH2-S (O)-S-CH2-CH=CH2 molecular formula: C6H10S20, " garlicin " has stronger antibacterial and anti-inflammation functions, all has suppression or killing action to multiple coccus, bacillus, fungus, virus etc.; Garlicin significantly suppresses or killing action as staphylococcus, meningitis, Diplococcus pneumoniae, streptococcus and diphtheria, dysentery, escherichia coli, typhoid fever, paratyphoid fever, pertussis, tubercule bacillus and vibrio cholera etc. have various pathogens; Candida albicans is comprised to multiple pathomycete and has suppression or killing action; Good therapeutical effect is had to trichomonal vaginitis,
5, bromelain
Containing abundant protease in " bromelain ", in addition also containing phosphatase, peroxidase etc.Clinical medicine has many functions, as anti-inflammatory, improve joint and muscular injuries, remove wound slough, in addition, have the effect such as enhancing immunity and anticancer growth, Fructus Ananadis comosi is rich in trace element, can supplement the needs of human body.Fructus Ananadis comosi is nutritious, and its composition comprises saccharide, protein, fat, vitamin A, B1, B2, C, proteolytic enzyme and calcium, phosphorus, ferrum, organic acid, nicotinic acid etc., especially the highest with Vitamin C content;
6, trehalose
Trehalose is made up of with 1,1-glycosidic bond two glucose molecules, and nonreducing sugar has 3 kinds of isomers and trehalose (α, α), isotrehalose (β, β) and neotrehalose (α, β)
" trehalose " is except can as except the excellent activity protective agent of pharmaceutical grade protein, enzyme, vaccine and other biological goods; still cytoactive is kept; to organism, there is magical protective effect; be the super Moisture factor of a new generation, therefore have the good reputation of " sugar of life " in scientific circles.The special literary composition evaluated trehalose once delivered by " nature " magazine of internal authority in July, 2000, the article pointed out: " for many life entities; the being and not being of trehalose, meaning life or death " " trehalose " is a large amount of for food, beverage, medicine, cosmetics industry;
7, lactic acid
Be somebody's turn to do the lactic acid in " compositions ", chemical name is 2 hydroxy propanoic acid or α-hydracrylate, finds at first from clabber, therefore being commonly called as lactic acid, lactic acid is colourless or light yellow viscous liquid, and fusing point is 180C, odorless, there is tart flavour, have hygroscopicity, can water-soluble, ethanol and glycerol.Lactic acid has sterilization effect, and lactic acid is in a large number for medicine, food, beverage, cosmetics industry;
8, " nutrient water solution ", the nutrient in this " compositions " is be the activator of multiple enzyme, also plays the protective effect to above-mentioned active matter.
" compositions of control female vulva inflammation " is: liquid, color of soy sauce or beans are yellow, and pH value 1.0-4.0, is made up of following steps:
1), by above-mentioned percentage by weight " trehalose " being dissolved into aqueous solution with distilled water, is aqueous trehalose solution,
2), by above-mentioned percentage by weight aqueous trehalose solution is entered in EM probiotic bacteria stock solution, stirs,
3), by above-mentioned percentage by weight ocean ferment is added in " 2) ", stirs,
4), by above-mentioned percentage by weight Rhizoma Zingiberis Recens ferment is added in " 3) ", stirs,
5), by above-mentioned percentage by weight uncooked garlic element is added in " 4) ", stir
6), by above-mentioned percentage by weight bromelain is added in " 5) ", stir
7), by above-mentioned percentage by weight added at leisure by lactic acid in " 6) ", limit adds at leisure, while stir, to pH value 1.0-4.0; Static 24-72 hour; Mend 100% with distilled water to filter, be this " compositions of control female vulva inflammation ".
Above steps is carried out at normal temperatures and pressures.
Detailed description of the invention
" compositions " of the present invention is made up of following compositions in weight percentage:
Embodiment 1
Raw material (kilogram) is taken by following proportioning:
1, EM probiotic bacteria stock solution 60,2, ocean ferment 5,3, bromelain 10,4, Rhizoma Zingiberis Recens ferment 10,5, trehalose 2,6, nutrient 0.3,7, organic acid soln is appropriate, 8, pure water surplus to 100;
Embodiment 2
Raw material (kilogram) is taken by following proportioning:
1, EM probiotic bacteria stock solution 50,2, ocean ferment 5,3, bromelain 15,4, Rhizoma Zingiberis Recens ferment 15,5, trehalose 2,6, nutrient 0.3,7, organic acid soln is appropriate, 8, pure water surplus to 100.
Production method is as follows:
(1), first " trehalose " is dissolved into aqueous solution with distilled water;
(2), again " trehalose " solution is entered in EM probiotic bacteria stock solution, stir;
(3), ocean ferment add in " 2) ", stir;
(4), Rhizoma Zingiberis Recens ferment is added in " 3) " stir;
(5), garlicin add in " 4) ", stir;
(6), bromelain adds in " 5) ", stirs
(7), lactic acid adds in " 6) " at leisure, and limit adds at leisure, while stir, to pH value 1.0-4.0; Static 24-72 hour; Mend 100% with distilled water to filter, be this " compositions of control female vulva inflammation ".
Above steps is carried out at normal temperatures and pressures.
Claims (5)
1. prevent and treat a compositions for female vulva inflammation, it is characterized in that he is made up of the raw material of following percentage by weight:
EM probiotic bacteria stock solution 40-70, ocean ferment 10-20, Rhizoma Zingiberis Recens ferment 5-10, garlicin 0.3-0.5, bromelain 5-10, trehalose 1-8, lactic acid are appropriate, nutrient 0.1-0.5, pure water surplus to 100.
2. the compositions of control female vulva inflammation according to claim 1, wherein the weight ratio of each raw material is:
-EM probiotic bacteria stock solution, 50-60, ocean ferment 10-15, bromelain 10-15, Rhizoma Zingiberis Recens ferment 8-10, trehalose 1-8, nutrient 0.1-0.5, lactic acid are appropriate, pure water surplus to 100.
3. control female vulva inflammation compositions according to claim 1, wherein the weight ratio of each raw material is: EM probiotic bacteria stock solution 60, ocean ferment 5, bromelain 10, Rhizoma Zingiberis Recens ferment 10, trehalose 2, nutrient 0.3, lactic acid are appropriate, pure water surplus to 100.
4. according to claim 1,2,3, the compositions of described control female vulva inflammation, it is characterized in that said composition, is that liquid, color of soy sauce or beans are yellow, pH value 1.0-4.0.
5. the preparation method of the compositions of control female vulva inflammation according to claim 4, it is characterized in that, production method is as follows:
(1), first " trehalose " is dissolved into aqueous solution with distilled water,
(2), again " trehalose " solution is entered in EM probiotic bacteria stock solution, stirs,
(3), ocean ferment add in " 2) ", stir,
(4), Rhizoma Zingiberis Recens ferment add in " 3) " and stir,
(5), garlicin add in " 4) ", stir,
(6), bromelain adds in " 5) ", stirs,
(7), lactic acid adds in " 6) " at leisure, and limit adds at leisure, while stir, pH value is adjusted to 1.0-4.0, and static 24-72 hour, mends 100 with distilled water, filters, and is and " should prevents and treats compositions of female vulva inflammation ".
Above steps is carried out at normal temperatures and pressures.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410578939.6A CN104399017A (en) | 2014-10-27 | 2014-10-27 | Composition for prevention and treatment of female vulva inflammation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410578939.6A CN104399017A (en) | 2014-10-27 | 2014-10-27 | Composition for prevention and treatment of female vulva inflammation |
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| Publication Number | Publication Date |
|---|---|
| CN104399017A true CN104399017A (en) | 2015-03-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410578939.6A Pending CN104399017A (en) | 2014-10-27 | 2014-10-27 | Composition for prevention and treatment of female vulva inflammation |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105288218A (en) * | 2015-11-23 | 2016-02-03 | 西安木本贞生物科技有限公司 | Probiotics composite |
| CN105942490A (en) * | 2016-03-30 | 2016-09-21 | 北京森源华诚科技发展有限公司 | Compound enzyme composition for preventing and curing hyperlipidemia, hyperglycemia, and hypertension |
| CN106265864A (en) * | 2016-08-30 | 2017-01-04 | 王守亮 | A kind of compound probiotic for reproductive system and its production and use |
| CN109864965A (en) * | 2019-03-28 | 2019-06-11 | 叶绿芝生物科技（中山）有限公司 | A kind of gold skin base solution composition |
| CN110038121A (en) * | 2019-04-23 | 2019-07-23 | 深圳前海千水生物科技有限公司 | A kind of plant complex enzyme gynaecology detoxicating gel |
-
2014
- 2014-10-27 CN CN201410578939.6A patent/CN104399017A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105288218A (en) * | 2015-11-23 | 2016-02-03 | 西安木本贞生物科技有限公司 | Probiotics composite |
| CN105942490A (en) * | 2016-03-30 | 2016-09-21 | 北京森源华诚科技发展有限公司 | Compound enzyme composition for preventing and curing hyperlipidemia, hyperglycemia, and hypertension |
| CN106265864A (en) * | 2016-08-30 | 2017-01-04 | 王守亮 | A kind of compound probiotic for reproductive system and its production and use |
| CN109864965A (en) * | 2019-03-28 | 2019-06-11 | 叶绿芝生物科技（中山）有限公司 | A kind of gold skin base solution composition |
| CN110038121A (en) * | 2019-04-23 | 2019-07-23 | 深圳前海千水生物科技有限公司 | A kind of plant complex enzyme gynaecology detoxicating gel |
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Application publication date: 20150311 |
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