CN106511114A - Broad spectrum bactericidal pure natural orange extract essence and preparation method thereof - Google Patents
Broad spectrum bactericidal pure natural orange extract essence and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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Abstract
The invention provides broad spectrum bactericidal pure natural orange extract essence and a preparation method thereof. Active ingredients of the broad spectrum bactericidal pure natural orange extract essence comprise hesperidin, neohesperidin, naringin, limonin, vitamin P, hesperetin and vitamin C. The broad spectrum bactericidal pure natural orange extract essence is pure natural citrus plant extract, has broad-spectrum antibacterial activity and is strong, efficient, safe and non-toxic. The main active ingredient orange extract essence is natural, has no any toxic or side effect, is an organic active ingredient separated from the natural citrus fruit, is a native antioxidant bacteriostatic agent, can break the microbial cell membrane under combined action of complex vitamin polymers, effectively inhibits staphylococcus aureus, escherichia coli and candida albicans and prevents bacterial resistance to drugs. The vitamin polymer has the effect of nourishing the skin and is the ideal native antibacterial agent.
Description
Technical field
The present invention relates to a kind of Fructus Citri tangerinae extracts elite.
Background technology
In the vagina of women, various different floras of living always, in addition to protentomon, funguses, are also needed including a lot
Oxygen bacterium and anaerobe, these microorganisms can be divided into commensalism microorganism and pathologic microorganism, have antagonism between them.Just
In the case of often, in occupation of leading position, it is a kind of probioticss to lactobacilluss, can then make the moon by glycogenolysis into lactic acid
In road, environment is in faintly acid, so as to suppress the growth reproduction of other pathogenic bacterium such as mycete, maintains vaginal microbial flora balance, is unlikely to draw
Send out disease.But, vaginal environment is often subject to itself product of host metabolism product, antibacterial and extrinsic factor (sexual intercourse, use alkalescence
Bath gel or clear water are rinsed) and it is unstable.Bacterial vaginosis be due to ability of Lactobacillus in human vagina reduce and other antibacterials are a large amount of
Breeding is caused a disease.In order to prevent various vaginitiss, people are usually used medicine font size, disappear font size or adornment font size washing liquid, disinfection pad etc.,
And the main active of these conditioning liquids is mostly hibitane, hibitane has broad-spectrum sterilization, bacteriostasis, including leather
Blue positive and negative bacterium, funguses and some viruses.Human body skin, oral mucosa, disease in the female sexual system majority are by several
More typically, often there are various inflammatory reactions to antibacterial MOI in lesions position, and Jing often widely applies Western medicine to have certain secondary work
With, and Chinese medicine has the shortcomings that action is slow.
The content of the invention
The shortcoming of prior art in view of the above, present invention aim at providing a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae extraction essence
China and preparation method thereof, the characteristics of natural Fructus Citri tangerinae extraction elite has efficient, nontoxic, noresidue, can effectively kill golden yellow Fructus Vitis viniferae
Coccus, Candida albicans, escherichia coli antibacterial.
For achieving the above object and other related purposes, the present invention provides a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae and extracts elite, its
Effective ingredient includes that hesperidin, neohesperidin, naringin, limonin, Citrin, hesperetin and vitamin C are made jointly
With, can prevent cellular plasm film absorb aminoacid, block Cellular respiration, so as to reach destruction microbial cell film work
With playing, be pure natural truly
Physical sterilization product.
Preferably, wherein, hesperidin proportion is 0.2-18 weight portions；Neohesperidin proportion is 0.04-
1.24 weight portion；Naringin proportion is 0.015-0.86 weight portions；Limonin proportion is 0.01-0.5 weights
Amount part；Citrin proportion is 0.05-2.5 weight portions；Hesperetin proportion is 0.03-0.85 weight portions；Dimension
Raw element C proportions are 0.25-13.8 weight portions.
Preferably, wherein, hesperidin proportion is 8-12 weight portions；Neohesperidin proportion is 0.076-1.02 weights
Amount part；Naringin proportion is 0.03-0.26 weight portions；Limonin proportion is 0.016-0.13 weight portions；Dimension life
Plain P proportions are 0.08-0.15 weight portions；Hesperetin proportion is 0.06-0.33 weight portions；Shared by vitamin C
Ratio is 5.2-8.24 weight portions.
Preferably, wherein, hesperidin proportion is 10 weight portions；Neohesperidin proportion is 1 weight portion；Naringin
Proportion is 0.25 weight portion；Limonin proportion is 0.1 weight portion；Citrin proportion is 0.1 weight
Part；Hesperetin proportion is 0.25 weight portion；Vitamin C proportion is 7 weight portions.
Within this range, hesperidin can play antiinflammatory antiviral, strengthen the effect of vitamin C effect.Neohesperidin exists
Citrin assists lower performance to maintain capillary permeability, the effect of sterilization anticancer.Naringin can play antimicrobial antiphlogistic, resist
Virus, the effect of anti-peroxidation.Limonin can strengthen naringin and play suppression tumor, the effect of anticancer.Citrin can be sent out
Wave the effect for preventing vitamin C to be oxidized, strengthening capillary permeability, prevent injury with blood-stasis.Hesperetin can play suppression inflammatory
The mediation of medium, the effect for removing peroxynitrite.It is anti-bad that vitamin C and Citrin collaboration can strengthen performance
Disorders of blood, promotion collagen protein synthesis, prevention gingival atrophy and bleeding, antioxidative effect.
A kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae extracts the preparation method of elite, will be citrus fruit raw material pressure pulverizing broken, then carries out
Extraction, extraction process include non-volatile solvents extraction, the extraction of volatile solvent extract, water, alcohol and water extraction, alcohol extraction,
Non-volatile solvents extraction acquisition is non-alcohol extract, needs to remove, and alcohol and water is extracted for removing tincture, to volatile solvent
Extract, water extraction, alcohol extract obtained solution and are removed solvent, and layering obtains oleoresin, extractum, solid phase extraction thing three
Class, removes oleoresin and solid phase extraction thing, and extractum is carried out alcohol extraction again, easily concentrating after then extracting to alcohol,
Obtain Fructus Citri tangerinae extraction elite.
Preferably, it is stored in -10-0 DEG C of temperature after during solvent is removed by liquid mixing, receives after layering
Collection supernatant simultaneously mixes with fraction is collected before, adjusts PH to 3.2-5.0, adjusts acidity to 0.01-0.02%.
Preferably, the centrifugal filter filtering and concentrating of 130 mesh is adopted during concentration, filtering residue is removed.
As described above, a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae that the present invention is provided extracts elite and preparation method thereof, with following
Beneficial effect：It 100% is pure natural citrus plants extract that the present invention is, with broad-spectrum antibacterial, strength efficiently, safety non-toxic etc.
Feature.Its principle active component Fructus Citri tangerinae extraction elite be it is primary natural, it is without any side effects, be to separate from natural citrus fruit
Primary antibacterial organic active ingredients, be a kind of primary non-oxidizability antibacterial, its complicated vitamin polymer is made jointly
With the cell membrane of destruction microorganism, effectively suppress staphylococcus aureuses, escherichia coli, Candida albicans, prevent antibacterial from producing
Toleration.Vitamin polymer possesses effect of nourishes rough skin, is preferable natural primary antibacterial.
Description of the drawings
Fig. 1 is to prepare the Making programme that broad-spectrum sterilization pure natural Fructus Citri tangerinae extracts elite.
Fig. 2 is that the natural Fructus Citri tangerinae for preparing extracts elite to escherichia coli biocidal property test result.
Fig. 3 is that the natural Fructus Citri tangerinae for preparing extracts elite to staphylococcus aureuses property test result.
Fig. 4 is that the natural Fructus Citri tangerinae for preparing extracts elite to Candida albicans test result.
Specific embodiment
Embodiments of the present invention are illustrated by particular specific embodiment below, those skilled in the art can be by this explanation
Content disclosed by book understands other advantages and effect of the present invention easily.
The present invention provides a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae extraction elite its effective ingredient includes hesperidin, neohesperidin, Fructus Citri grandiss
Skin glycoside, limonin, Citrin, hesperetin and vitamin C collective effect, can prevent cellular plasm film from absorbing amino
Acid, blocks Cellular respiration, so as to reach the effect of destruction microbial cell film, plays
It is infested to wait harmful microbe effect, it is pure natural physical sterilization product truly.
Embodiment one, wherein, hesperidin proportion is 10 weight portions；Neohesperidin proportion is 1 weight portion；Pericarpium Citri grandiss
Glycoside proportion is 0.25 weight portion；Limonin proportion is 0.1 weight portion；Citrin proportion is 0.1 weight
Part；Hesperetin proportion is 0.25 weight portion；Vitamin C proportion is 7 weight portions.
Embodiment two, wherein, hesperidin proportion is 8 weight portions；Neohesperidin proportion is 0.076 weight portion；
Naringin proportion is 0.03 weight portion；Limonin proportion is 0.016 weight portion；Citrin proportion is
0.08 weight portion；Hesperetin proportion is 0.06 weight portion；Vitamin C proportion is 5.2 weight portions.
Embodiment three, wherein, hesperidin proportion is 12 weight portions；Neohesperidin proportion is 1.02 weight portions；
Naringin proportion is 0.26 weight portion；Limonin proportion is 0.13 weight portion；Citrin proportion is
0.15 weight portion；Hesperetin proportion is 0.33 weight portion；Vitamin C proportion is 8.24 weight portions.
Within this range, hesperidin can play antiinflammatory antiviral, strengthen the effect of vitamin C effect.Neohesperidin exists
Citrin assists lower performance to maintain capillary permeability, the effect of sterilization anticancer.Naringin can play antimicrobial antiphlogistic, resist
Virus, the effect of anti-peroxidation.Limonin can strengthen naringin and play suppression tumor, the effect of anticancer.Citrin can be sent out
Wave the effect for preventing vitamin C to be oxidized, strengthening capillary permeability, prevent injury with blood-stasis.Hesperetin can play suppression inflammatory
The mediation of medium, the effect for removing peroxynitrite.It is anti-bad that vitamin C and Citrin collaboration can strengthen performance
Disorders of blood, promotion collagen protein synthesis, prevention gingival atrophy and bleeding, antioxidative effect.
As shown in Figure 1, there is provided a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae extracts the preparation method of elite, citrus fruit raw material pressure is ground
Crush, then extracted, extraction process includes non-volatile solvents extraction, the extraction of volatile solvent extract, water, alcohol and water
Extraction, alcohol extraction, non-volatile solvents extraction acquisition is non-alcohol extract, needs to remove, and alcohol and water is extracted for removing tincture,
Obtained solution is extracted to volatile solvent extract, water extraction, alcohol and is removed solvent, layering acquisition oleoresin, extractum, admittedly
Three class of body extract, removes oleoresin and solid phase extraction thing, and extractum is carried out alcohol extraction again, easy after then extracting to alcohol
Concentrated, obtained Fructus Citri tangerinae extraction elite.
In the present embodiment, it is stored in -10-0 DEG C of temperature after during solvent is removed by liquid mixing, is layered
Supernatant is collected afterwards and is mixed with fraction is collected before, adjust PH to 3.2-5.0, adjust acidity to 0.01-0.02%.
In the present embodiment, the centrifugal filter filtering and concentrating of 130 mesh is adopted during concentration, filtering residue is removed.
Fructus Citri tangerinae extraction elite to producing is tested, and detects its bactericidal property.
Experimental procedure is as follows：
(1) equipment
1st, test specimen：Orange essence NTS01 of the present invention.
2nd, test strain：Escherichia coli ATCC8739, staphylococcus aureuses ATCC6538, Candida albicans
ATCC10231。
3rd, positive control：The positive control of escherichia coli and staphylococcus aureuses be ammonia benzyl antibiotic, Candida albicans
Positive control be fluconazole.Used by positive control, concentration is 100mg/ml.
4th, test equipment：Liquid-transfering gun, Tube propagation ware, biochemical cultivation case, super-clean bench etc.
(2) method
1st, this experiment is detected using inhibition zone method
2nd, orange essence sample is carried out into 10 times 100 times 1000 times of dilutions.
Sample NTS01 stock solutions are to three kinds of target bacterium escherichia coli, golden gold staphylococcuses, the biocidal property of Candida albicans
Detection.
(3) result
The antibacterial positive control MIC of sample effect test stock solution
Numbering time strain loop diameter（mm）Antibacterial circle diameter（mm）
NTS01 24h escherichia coli 23 32 1/1000
Staphylococcus aureuses 26 40 1/5000
Candida albicans 28 13 1/3000
* MIC has the maximum dilution multiple of bacteriostatic activity for stock solution
This experimental result detects that using inhibition zone method the antibacterial result that 10,100 and 1000 times of diluted sample vides infra shown in figure,
By experimental result as can be seen that sample NTS01 stock solutions are respectively provided with obvious bacteriostatic activity to three kinds of target bacterium, which is to escherichia coli
Be significantly lower than positive control with the bacteriostatic activity of staphylococcus aureuses, but to the bacteriostatic activity of Candida albicans apparently higher than
Positive control, sample are respectively to the maximum dilution multiple of escherichia coli, three kinds of bacterium of staphylococcus aureuses and Candida albicans
1000th, 5000 and 3000 times.
Bacteriostatic activity result figure：
（1）For trying strain：Escherichia coli
Fig. 2 escherichia coli biocidal property is tested
Left figure：Fructus Citri tangerinae extraction stock solution dilution 101Dilution 102Dilution 103There is biocidal property to escherichia coli
Right figure：Fructus Citri tangerinae extracts stock solution water antibiotic to escherichia coli biocidal property.Fructus Citri tangerinae extraction stock solution has certain biocidal property
（2）For trying strain：Staphylococcus aureuses
Fig. 3 is tested for staphylococcus aureuses biocidal property
Left figure：Fructus Citri tangerinae extraction stock solution dilution 101Dilution 102Dilution 103There is biocidal property to staphylococcus aureuses
Right figure：Fructus Citri tangerinae extracts stock solution water Antibiotics On Staphylococcus Aureus biocidal property.Fructus Citri tangerinae extraction stock solution has certain biocidal property
（3）For trying strain：Candida albicans
Fig. 4 Candida albicans biocidal property is tested
Left figure：Fructus Citri tangerinae extraction stock solution dilution 101Dilution 102Dilution 103There is biocidal property to Candida albicans
Right figure：Antibiotic is to Candida albicans biocidal property.Antibiotic reads ball without biocidal property to white
The key technical indexes of Project Product
Antibacterial index：8099 stock solution of escherichia coli acts on 2min, bacteriostasis rate >=90.0%；Staphylococcus aureus liquid is made
With 2min, bacteriostasis rate >=90.0%；To funguses（Candida albicans）Stock solution acts on 2min, bacteriostasis rate >=90.0%.
Microbiological contaminant index：Total number of bacterial colonies（cfu/ml）≤200；Coliform must not be detected；Golden yellow Fructus Vitis viniferae
Coccus must not detect；Pseudomonas aeruginosa must not be detected；Hemolytic streptococcuss must not be detected；Fungus colony sum（cfu/ml）≤
100。
Stability indicator：Product is deposited 90 days under the conditions of 37 DEG C, relative humidity 75%, and product is to escherichia coli, gold
Staphylococcus aureus, Candida albicans bacteriostasis rate still >=90.0%.
Jiangsu Prov. Disease Preventing and Controlling Center's toxicological test examining report shows：Acute eye irritation test belongs to nonirritant；
Multiple intact skin irritant test：For nonirritant;Tests For Irritating Effects are nonirritant；Acute oral toxicity is tried
Test（Mice）：The nontoxic level in true border.Mice bone marrow micronucleus：Do not detect which to the thermophilic polychromatophilia of mouse bone marrow cells
The cause micronucleus effect of erythrocyte.
Suzhou Municipal Disease Control and Prevention Center examining report shows：Stock solution is acted on 2 minutes, to Candida albicans bacteriostasis rate
100%, to staphylococcus aureuses bacteriostasis rate 100%, to escherichia coli bacteriostasis rate 100%.
Except above-mentioned excellent antibacterial effect, Fructus Citri tangerinae extraction elite is also very excellent in terms of security performance：
A, safety non-toxic, will not it is carcinogenic, will not induced gene mutation；
B, the stability of biological degradable, good continuous action and biological agent；
C, to the nonirritant, harmless of skin mucosa, do not change taste of food and color.
Efficiently, pure natural plant formula, sterilization, maintenance unite two into one Fructus Citri tangerinae extraction elite broad-spectrum, rich in abundant natural
Plant nutrient ingredient, nourish skin, defending and fighting against diseases, and different from the single anti-microbial type product of general common body local,
Which is related to partes corporis humani position sterilizing disease-preventing, therefore nurses before this just has wide utilization and exploitation on one side in Personal hygiene
On the way.The market orientation of this Project Product：The daily bactericidal nursing of infant, the bactericidal washing liquid nursing of female consumer,
Mouth care and collutory, agricultural, forestry, the animals and plants bactericidal insect-pest of animal husbandry, food fresh keeping anti-corrosion.
In sum, the present invention provides a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae extraction elite and preparation method thereof, and the present invention is used
Fructus Citri tangerinae extraction elite be 100% be pure natural citrus plants extract, with broad-spectrum antibacterial, strength efficiently, safety non-toxic the features such as.
Its principle active component Fructus Citri tangerinae extraction elite be it is primary natural, it is without any side effects, be the original separated from natural citrus fruit
Raw antibacterial organic active ingredients, are a kind of primary non-oxidizability antibacterial, and its complicated vitamin polymer collective effect is broken
The cell membrane of bad microorganism, effectively suppresses staphylococcus aureuses, escherichia coli, Candida albicans, prevents antibacterial from producing tolerance
Property.Vitamin polymer possesses effect of nourishes rough skin, is preferable natural primary antibacterial.So, the present invention effectively overcomes
Various shortcoming of the prior art and have high industrial utilization.
The principle and its effect of above-described embodiment only illustrative present invention, it is of the invention not for limiting.It is any ripe
The personage for knowing this technology all can carry out modifications and changes to above-described embodiment under the spirit and the scope without prejudice to the present invention.Cause
This, those of ordinary skill in the art is complete with institute under technological thought without departing from disclosed spirit such as
Into all equivalent modifications or change, should by the present invention claim be covered.
Claims (7)
1. a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae extracts elite, it is characterised in that：Its effective ingredient includes hesperidin, neohesperidin, Fructus Citri grandiss
Skin glycoside, limonin, Citrin, hesperetin and vitamin C collective effect.
2. a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae according to claim 1 extracts elite, it is characterised in that：Wherein, hesperidin institute
Accounting example is 0.2-18 weight portions；Neohesperidin proportion is 0.04-1.24 weight portions；Naringin proportion is
0.015-0.86 weight portions；Limonin proportion is 0.01-0.5 weight portions；Citrin proportion is
0.05-2.5 weight portions；Hesperetin proportion is 0.03-0.85 weight portions；Vitamin C proportion is 0.25-
13.8 weight portions.
3. a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae according to claim 2 extracts elite, it is characterised in that：Wherein, hesperidin institute
Accounting example is 8-12 weight portions；Neohesperidin proportion is 0.076-1.02 weight portions；Naringin proportion is 0.03-
0.26 weight portion；Limonin proportion is 0.016-0.13 weight portions；Citrin proportion is 0.08-0.15 weights
Amount part；Hesperetin proportion is 0.06-0.33 weight portions；Vitamin C proportion is 5.2-8.24 weight portions.
4. a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae according to claim 3 extracts elite, it is characterised in that：Wherein, hesperidin institute
Accounting example is 10 weight portions；Neohesperidin proportion is 1 weight portion；Naringin proportion is 0.25 weight portion；Fructus Citri Limoniae is bitter
Plain proportion is 0.1 weight portion；Citrin proportion is 0.1 weight portion；Hesperetin proportion is 0.25 weight
Part；Vitamin C proportion is 7 weight portions.
5. a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae extracts the preparation method of elite, it is characterised in that：Will be citrus fruit raw material pressure pulverizing broken,
Then extracted, extraction process include non-volatile solvents extraction, volatile solvent extract, water extraction, alcohol and water extraction,
Alcohol is extracted, and non-volatile solvents extraction acquisition is non-alcohol extract, needs to remove, and alcohol and water is extracted for removing tincture, to waving
The property sent out solvent extract, water extraction, alcohol extract obtained solution and are removed solvent, and layering obtains oleoresin, extractum, solid extract
Three class of thing is taken, removes oleoresin and solid phase extraction thing, extractum is carried out alcohol extraction again, easily carrying out after then extracting to alcohol
Concentration, obtains Fructus Citri tangerinae extraction elite.
6. a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae according to claim 5 extracts the preparation method of elite, it is characterised in that：Going
To be stored in after liquid mixing in -10-0 DEG C of temperature during except solvent, after layering collect supernatant and with receive before
Collection fraction mixing, adjusts PH to 3.2-5.0, adjusts acidity to 0.01-0.02%.
7. a kind of broad-spectrum sterilization pure natural Fructus Citri tangerinae according to claim 6 extracts the preparation method of elite, it is characterised in that：Dense
The centrifugal filter filtering and concentrating of 130 mesh is adopted during contracting, filtering residue is removed.
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| CN112293718A (en) * | 2020-06-04 | 2021-02-02 | 苏州汉德瑞生物工程有限公司 | Citrus extract and preparation method and application thereof |
| TWI756492B (en) * | 2017-11-20 | 2022-03-01 | 日商旭化成股份有限公司 | Concentrating system for articles containing solvent, method for concentrating articles containing solvent and concentrate |
| CN114748247A (en) * | 2022-04-20 | 2022-07-15 | 倍舒特(天津)卫生用品有限公司 | Sanitary towel capable of increasing comfort |
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| TWI756492B (en) * | 2017-11-20 | 2022-03-01 | 日商旭化成股份有限公司 | Concentrating system for articles containing solvent, method for concentrating articles containing solvent and concentrate |
| CN111616292A (en) * | 2020-05-25 | 2020-09-04 | 广州素旺生物科技有限公司 | Sterilization and bacteriostasis disinfectant and preparation method thereof |
| CN112293718A (en) * | 2020-06-04 | 2021-02-02 | 苏州汉德瑞生物工程有限公司 | Citrus extract and preparation method and application thereof |
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Address after: 215000 1 Kwun Tong Road, Suzhou Xiangcheng District Economic Development Zone, Suzhou, Jiangsu Applicant after: Dr. orange Biotechnology (Suzhou) Co., Ltd. Address before: 215000 1 Kwun Tong Road, Suzhou Xiangcheng District Economic Development Zone, Suzhou, Jiangsu Applicant before: Suzhou Li Li Ya Biological Technology Co., Ltd. |
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Application publication date: 20170322 |