CN112586441A - African swine fever prevention and control method and application thereof - Google Patents
African swine fever prevention and control method and application thereof Download PDFInfo
- Publication number
- CN112586441A CN112586441A CN202011442555.3A CN202011442555A CN112586441A CN 112586441 A CN112586441 A CN 112586441A CN 202011442555 A CN202011442555 A CN 202011442555A CN 112586441 A CN112586441 A CN 112586441A
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- swine fever
- african swine
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Abstract
The invention relates to the technical field of prevention and control of African swine fever, and particularly relates to a method for preventing and controlling African swine fever and application thereof. The traditional Chinese medicine formula improves the immunity and the resistance of live pigs by improving the environment in an organism, greatly reduces the infection probability and pressure by using strong alkali for disinfection in a large environment, avoids the protection of a biological membrane in a complex environment around the live pigs to pathogenic microorganisms by using a composite disinfectant compounded by glacial acetic acid, hydrogen peroxide and phosphoric acid for disinfection in a pigsty, avoids the harm of the disinfectant to the live pigs, has no pollution to the environment, changes the pH value of the disinfectant and uses oxides in a superposition way, furthest reduces the survival and reproduction possibility of the pathogenic microorganisms, can effectively prevent and control the occurrence of African swine fever, and has obvious effect; and the limitation is small, and the prevention and control cost is low.
Description
Technical Field
The invention relates to the technical field of prevention and control of African swine fever, and particularly relates to a method for preventing and controlling African swine fever and application thereof.
Background
Since the occurrence of African swine fever, the swine fever causes serious harm to the swine industry and brings heavy attacks to the industry. Because the production conditions of the pig industry are large in difference and different in scale degree, and the sanitary conditions of a pigsty are influenced, the existing epidemic disease prevention and control method has great limitation, for example, the existing prevention and control method for the African swine fever mainly adopts the traditional disinfection medicaments (disinfectant disinfection such as glutaraldehyde and potassium dihydrogen sulfate) to achieve the aim of controlling the biosafety so as to prevent the disease, other effective methods are not available, and no medicament or vaccine is available for prevention and control; moreover, the existing prevention and control method has the disadvantages of large investment, high prevention and control cost and poor prevention and control effect.
Disclosure of Invention
In order to solve the problems, the invention aims to provide a method for preventing and controlling African swine fever and application thereof. The method for preventing and controlling the African swine fever provided by the invention can effectively prevent and control the occurrence of the African swine fever, and has obvious effect; and the limitation is small, and the prevention and control cost is low.
In order to achieve the purpose, the invention provides the following technical scheme:
the invention provides an African swine fever prevention and control method, which comprises the following steps:
adopting caustic soda solution to disinfect the periphery of the pigsty;
disinfecting the pigs by adopting a compound disinfectant; the composite disinfectant comprises 1-3% of glacial acetic acid, 0.135-0.81% of hydrogen peroxide, 0.1% of phosphoric acid and the balance of water by volume concentration percentage;
feeding traditional Chinese medicine feed; the traditional Chinese medicine feed comprises a traditional Chinese medicine composition and a basic feed; the mass ratio of the traditional Chinese medicine composition to the basic feed is (0.5-2): 100, respectively; the traditional Chinese medicine composition comprises the following raw materials in parts by mass: 5-35 parts of burdock, 10-25 parts of fructus forsythiae, 5-20 parts of dandelion, 5-10 parts of subprostrate sophora, 5-10 parts of folium phyllanthi, 5-10 parts of oriental wormwood, 5-10 parts of radix bupleuri, 5-15 parts of semen plantaginis, 5-15 parts of poria cocos slice, 5-10 parts of radix scrophulariae, 5-10 parts of lithospermum, 5-20 parts of houttuynia cordata, 5-22 parts of cortex moutan, 5-20 parts of radix sophorae flavescentis, 5-25 parts of caulis polygoni multiflori, 5-25 parts of glossy privet fruit, 10-25 parts of Chinese yam, 5-10 parts of radix paeoniae alba and 5-15 parts of liquorice.
Preferably, the method for preventing and controlling African swine fever comprises prevention and control; when the African swine fever is prevented, the prevention opportunity is when epidemic situation does not occur or after an individual with abnormal epidemic situation elimination occurs; when the African swine fever control is carried out, the control is carried out at the moment that the abnormal pigs are still positive by adopting PCR detection after prevention.
Preferably, when prophylaxis is performed: the composite disinfectant comprises 1 percent of glacial acetic acid, 2 percent of glacial acetic acid, 0.135 percent of hydrogen peroxide, 0.81 percent of phosphoric acid and the balance of water according to volume concentration percentage;
the dosage of the disinfectant is 50-100 ml/m2(ii) a The disinfection frequency is 1-2 times/d;
the mass concentration of the caustic soda is 0.5 percent and 1.0 percent, and the dosage of the caustic soda solution is 50-100 ml/m2(ii) a The disinfection frequency is 1 time/d;
the mass ratio of the traditional Chinese medicine composition to the basic feed is (0.5, 1.5): 100.
preferably, when the control is performed: the composite disinfectant comprises glacial acetic acid (2%, 3%), hydrogen peroxide (0.6%, 0.81%), phosphoric acid (0.1%) and water (the balance) by volume concentration percentage;
the dosage of the disinfectant is 100ml/m2(ii) a The disinfection frequency is 3-5 times/d;
the mass concentration of the caustic soda is 1 percent and 2 percent]The amount of the caustic soda solution is 100ml/m2(ii) a The disinfection frequency is 1-2 times/d;
the mass ratio of the traditional Chinese medicine composition to the basic feed is [1.5,2 ]: 100.
preferably, the control further includes: and (3) carrying out full-group quantitative PCR detection every 3-5 days from the beginning of control, and removing positive individuals and fever individuals.
The invention also provides application of the African swine fever control method in the scheme in control of animal fulminating infection diseases.
Preferably, the animal virulent infectious disease comprises one or more of swine fever, ringworm disease, foot and mouth disease, blue ear disease and epidemic diarrhea.
Has the advantages that:
the invention provides an African swine fever prevention and control method which is characterized by comprising the following steps: adopting caustic soda solution to disinfect the periphery of the pigsty; disinfecting the pigs by adopting a compound disinfectant; the composite disinfectant comprises 1-3% of glacial acetic acid, 0.135-0.81% of hydrogen peroxide, 0.1% of phosphoric acid and the balance of water by volume concentration percentage; feeding traditional Chinese medicine feed; the traditional Chinese medicine feed comprises a traditional Chinese medicine composition and a basic feed; the mass ratio of the traditional Chinese medicine composition to the basic feed is (0.5-2): 100, respectively; the traditional Chinese medicine composition comprises the following raw materials in parts by mass: 5-35 parts of burdock, 10-25 parts of fructus forsythiae, 5-20 parts of dandelion, 5-10 parts of subprostrate sophora, 5-10 parts of folium phyllanthi, 5-10 parts of oriental wormwood, 5-10 parts of radix bupleuri, 5-15 parts of semen plantaginis, 5-15 parts of poria cocos slice, 5-10 parts of radix scrophulariae, 5-10 parts of lithospermum, 5-20 parts of houttuynia cordata, 5-22 parts of cortex moutan, 5-20 parts of radix sophorae flavescentis, 5-25 parts of caulis polygoni multiflori, 5-25 parts of glossy privet fruit, 10-25 parts of Chinese yam, 5-10 parts of radix paeoniae alba and 5-15 parts of liquorice. The traditional Chinese medicine formula improves the immunity and the resistance of live pigs by improving the environment in an organism, greatly reduces the infection probability and pressure by using strong alkali for disinfection in a large environment, avoids the protection of a biological membrane in a complex environment around the live pigs to pathogenic microorganisms by using a composite disinfectant compounded by glacial acetic acid, hydrogen peroxide and phosphoric acid for disinfection in a pigsty, avoids the harm of the disinfectant to the live pigs, has no pollution to the environment, changes the pH value of the disinfectant and uses oxides in a superposition way, furthest reduces the survival and reproduction possibility of the pathogenic microorganisms, can effectively prevent and control the occurrence of African swine fever, and has obvious effect; and the limitation is small, and the prevention and control cost is low.
Furthermore, the composite disinfectant provided by the invention not only can effectively prevent and control African swine fever, but also has good prevention and control effects on one or more severe infectious diseases in swine fever, ring disease, foot and mouth disease, blue ear disease and epidemic diarrhea, and can reduce the prevention and control times of other severe diseases while preventing and controlling African swine fever, thereby greatly reducing the prevention and control drug cost of swinery and improving the economic benefit.
Detailed Description
The invention provides an African swine fever prevention and control method, which comprises the following steps:
adopting caustic soda solution to disinfect the periphery of the pigsty;
disinfecting the pigs by adopting a compound disinfectant; the composite disinfectant comprises 1-3% of glacial acetic acid, 0.135-0.81% of hydrogen peroxide, 0.1% of phosphoric acid and the balance of water by volume concentration percentage;
feeding traditional Chinese medicine feed; the traditional Chinese medicine feed comprises a traditional Chinese medicine composition and a basic feed; the mass ratio of the traditional Chinese medicine composition to the basic feed is (0.5-2): 100, respectively; the traditional Chinese medicine composition comprises the following raw materials in parts by mass: 5-35 parts of burdock, 10-25 parts of fructus forsythiae, 5-20 parts of dandelion, 5-10 parts of subprostrate sophora, 5-10 parts of folium phyllanthi, 5-10 parts of oriental wormwood, 5-10 parts of radix bupleuri, 5-15 parts of semen plantaginis, 5-15 parts of poria cocos slice, 5-10 parts of radix scrophulariae, 5-10 parts of lithospermum, 5-20 parts of houttuynia cordata, 5-22 parts of cortex moutan, 5-20 parts of radix sophorae flavescentis, 5-25 parts of caulis polygoni multiflori, 5-25 parts of glossy privet fruit, 10-25 parts of Chinese yam, 5-10 parts of radix paeoniae alba and 5-15 parts of liquorice.
In the invention, the modes of the caustic soda solution sterilization, the compound disinfectant with pig sterilization and the traditional Chinese medicine feed feeding in the prevention and control method are not limited in time sequence, preferably, the caustic soda solution sterilization is carried out firstly, and the compound disinfectant with pig sterilization and the traditional Chinese medicine feed feeding are not limited in time sequence.
In the present invention, the method for prevention and control of African swine fever preferably comprises prevention and control; when the African swine fever is prevented, the prevention time is preferably when the epidemic situation does not occur or after an individual with abnormal epidemic situation elimination occurs; when controlling African swine fever, the timing of the control is preferably that abnormal swine is detected to be positive by PCR after prevention. When the invention is used for prevention and control, the periphery of the pigsty is preferably disinfected by adopting the caustic soda solution; a method for preventing and controlling the pig from being disinfected and feeding traditional Chinese medicine feed by adopting a compound disinfectant.
In the present invention, when the prevention is performed: the composite disinfectant is preferably glacial acetic acid (1%, 2%) in percentage by volume concentration]Hydrogen peroxide [ 0.135%, 0.81% ]]0.1 percent of phosphoric acid and the balance of water, and further preferably 1 to 1.5 percent of glacial acetic acid, 0.3 to 0.6 percent of hydrogen peroxide, 0.1 percent of phosphoric acid and the balance of water; the dosage of the disinfectant is preferably 50-100 ml/m2More preferably 70 to 100ml/m2Most preferably 70ml/m2(ii) a The disinfection frequency is preferably 1 time/d; the mass concentration of the caustic soda is preferably [ 0.5%, 1%), and more preferably 0.8%; the preferable dosage of the caustic soda solution is 50-100 ml/m2More preferably 70 to 100ml/m2Most preferably 70ml/m2(ii) a The disinfection frequency is preferably 1-2 times/d; the mass ratio of the traditional Chinese medicine composition to the basic feed is preferably [0.5, 1.5): 100, more preferably 1: 100. the invention can economically and effectively prevent African swine fever by controlling the concentration and the proportioning dosage of the caustic soda solution, the compound disinfectant and the traditional Chinese medicine feed.
In the present invention, when performing control: the composite disinfectant is preferably glacial acetic acid (2%, 3%)]Hydrogen peroxide (0.6%, 0.81%)]0.1% of phosphoric acid and the balance of water; further preferably 2.5 to 3 percent of glacial acetic acid, 0.7 to 0.8 percent of hydrogen peroxide, 0.1 percent of phosphoric acid and the balance of water; the disinfectant is preferably used in an amount of 100ml/m2(ii) a The disinfection frequency is preferably 3-5 times/d, and more preferably 5 times; the mass concentration of the caustic soda is preferably [ 1%, 2%]More preferably 1.5%; the amount of caustic soda solution used is preferably 100ml/m2(ii) a The disinfection frequency is preferably 1-2 times/d; the mass ratio of the traditional Chinese medicine composition to the basic feed is (1.5, 2)]:100, more preferably 1.5: 100. When the control is carried out, the method preferably further comprises the following steps: and (3) carrying out full-group quantitative PCR detection every 3-5 days from the beginning of control, and removing positive individuals and fever individuals. The invention can economically and effectively control African swine fever by controlling the concentration and the proportion of the caustic soda solution, the compound disinfectant and the traditional Chinese medicine feed.
The invention adopts the compound disinfectant to disinfect the pigs; the composite disinfectant comprises 1-3% of glacial acetic acid, 0.135-0.81% of hydrogen peroxide, 0.1% of phosphoric acid and the balance of water by volume concentration percentage.
In the present invention, the area with pig disinfection preferably includes a pigsty area other than a pigsty road.
Unless otherwise specified, the present invention does not require any particular source for each component of the composite disinfectant, and any commercially available product known to those skilled in the art may be used.
The glacial acetic acid in the composite disinfectant disclosed by the invention can play a good role in inactivating the African swine fever virus within a concentration range, and does not harm the health of pigs; meanwhile, after the feed additive is compounded with hydrogen peroxide and phosphoric acid, the pungent taste of glacial acetic acid can be relieved, the digestion of pigs can be promoted, the feed conversion efficiency is improved, and the production cost is saved.
In the invention, the raw material for preparing the hydrogen peroxide preferably comprises 27 volume percent hydrogen peroxide. By controlling the concentration of the hydrogen peroxide in the composite disinfectant, the invention not only can quickly and efficiently kill all pathogenic microorganisms including African swine fever virus, effectively prevent the spread and diffusion of infectious diseases through the excretion of the sick pigs, but also can disinfect the wounds of the pigs; meanwhile, after the compound disinfectant is compounded with glacial acetic acid and phosphoric acid, the compound disinfectant of hydrogen peroxide, glacial acetic acid and phosphoric acid is obtained, so that acid-resistant microorganisms and microorganisms protected by a cyst membrane or a biological membrane can be killed, the occurrence of African swine fever is effectively prevented and controlled, and the effect is obvious; and has small limitation and no pollution to the environment.
In addition, the effective environment temperature of the hydrogen peroxide solution is 0-45 ℃, the ordinary temperature of the pigsty environment is 15-28 ℃, the composite disinfectant sprayed to the swinery in the temperature environment can kill mites in 3min, and worm eggs such as roundworms and coccidian can be killed in 5min, so that the risk of disease propagation among the swinery is greatly reduced, and the health index of the swinery is improved.
In the present invention, the raw material for producing phosphoric acid preferably includes a phosphoric acid solution having a mass concentration of 85%. According to the invention, the phosphoric acid, the glacial acetic acid and the hydrogen peroxide are compounded, so that the stability of the hydrogen peroxide can be improved, and the effectiveness of the disinfectant can be improved; but also can reduce the irritation of hydrogen peroxide and glacial acetic acid and reduce the discomfort of the live pigs; meanwhile, the contact disinfection time of the effective content of the composite disinfectant and the dirt can be prolonged, and the disinfection efficiency is improved.
The invention preferably also provides a preparation method of the compound disinfectant, which comprises the step of mixing glacial acetic acid, phosphoric acid, hydrogen peroxide and water to obtain the compound disinfectant.
In the present invention, the mixing means preferably includes the steps of: mixing glacial acetic acid and phosphoric acid for the first time to obtain a mixed solution; and secondly, mixing the mixed solution, hydrogen peroxide and water to obtain the composite disinfectant. The present invention does not require any particular mixing means, and the compositions may be mixed in a manner known to those skilled in the art. According to the invention, phosphoric acid serving as a stabilizer is mixed with glacial acetic acid and then mixed with hydrogen peroxide, so that the composite disinfectant is more stable, the irritation of the hydrogen peroxide and the glacial acetic acid is further reduced, and the discomfort of live pigs is relieved.
The invention feeds the traditional Chinese medicine feed; the traditional Chinese medicine feed comprises a traditional Chinese medicine composition and a basic feed; the mass ratio of the traditional Chinese medicine composition to the basic feed is (0.5-2): 100, respectively; the traditional Chinese medicine composition comprises the following raw materials in parts by mass: 5-35 parts of burdock, 10-25 parts of fructus forsythiae, 5-20 parts of dandelion, 5-10 parts of subprostrate sophora, 5-10 parts of folium phyllanthi, 5-10 parts of oriental wormwood, 5-10 parts of radix bupleuri, 5-15 parts of semen plantaginis, 5-15 parts of poria cocos slice, 5-10 parts of radix scrophulariae, 5-10 parts of lithospermum, 5-20 parts of houttuynia cordata, 5-22 parts of cortex moutan, 5-20 parts of radix sophorae flavescentis, 5-25 parts of caulis polygoni multiflori, 5-25 parts of glossy privet fruit, 10-25 parts of Chinese yam, 5-10 parts of radix paeoniae alba and 5-15 parts of liquorice.
If not specifically stated, the invention has no special requirements for the sources of the components in the traditional Chinese medicine feed, and the invention can adopt commercial products which are well known to those skilled in the art.
The traditional Chinese medicine composition comprises, by mass, 5-35 parts of burdock, preferably 10-35 parts, and more preferably 25 parts.
The traditional Chinese medicine composition comprises 10-25 parts by mass of fructus forsythiae, preferably 10-20 parts by mass of fructus forsythiae, and more preferably 15 parts by mass of fructus forsythiae.
The traditional Chinese medicine composition comprises, by mass, 5-20 parts of dandelion, preferably 5-15 parts of dandelion, and more preferably 15 parts of dandelion. The dandelion is preferably whole dandelion and comprises dandelion roots and dandelion leaves.
The traditional Chinese medicine composition comprises, by mass, 5-10 parts of subprostrate sophora, preferably 5-8 parts, and more preferably 8 parts.
The traditional Chinese medicine composition comprises, by mass, 5-10 parts of beautyberry leaves, preferably 5-8 parts, and more preferably 8 parts.
The traditional Chinese medicine composition comprises, by mass, 5-10 parts of oriental wormwood, preferably 5-8 parts of oriental wormwood, and more preferably 8 parts of oriental wormwood. The present invention is not limited to the above-mentioned capillary artemisia, and commercially available products known to those skilled in the art may be used.
The traditional Chinese medicine composition comprises, by mass, 5-10 parts of radix bupleuri, preferably 5-8 parts of radix bupleuri, and more preferably 8 parts of radix bupleuri.
The traditional Chinese medicine composition comprises, by mass, 5-15 parts of plantain seeds, preferably 5-10 parts of plantain seeds, and more preferably 10 parts of plantain seeds.
The traditional Chinese medicine composition comprises, by mass, 5-15 parts of poria cocos slices, preferably 5-10 parts, and more preferably 10 parts.
The traditional Chinese medicine composition comprises, by mass, 5-10 parts of radix scrophulariae, preferably 5-8 parts, and more preferably 8 parts.
The traditional Chinese medicine composition comprises, by mass, 5-10 parts of lithospermum, preferably 5-8 parts of lithospermum, and more preferably 8 parts of lithospermum.
The traditional Chinese medicine composition comprises, by mass, 5-20 parts of houttuynia cordata, preferably 15-20 parts of houttuynia cordata, and more preferably 15 parts of houttuynia cordata.
The traditional Chinese medicine composition comprises, by mass, 5-22 parts of cortex moutan, preferably 15-22 parts, and more preferably 15 parts.
The traditional Chinese medicine composition comprises, by mass, 5-20 parts of radix sophorae flavescentis, preferably 15-20 parts of radix sophorae flavescentis, and more preferably 15 parts of radix sophorae flavescentis.
The traditional Chinese medicine composition comprises, by mass, 5-25 parts of vine of multiflower knotweed, preferably 20-25 parts, and more preferably 20 parts.
The traditional Chinese medicine composition comprises, by mass, 5-25 parts of glossy privet fruit, preferably 20-25 parts, and more preferably 20 parts.
The traditional Chinese medicine composition comprises, by mass, 10-25 parts of Chinese yam, preferably 20-25 parts of Chinese yam, and more preferably 20 parts of Chinese yam.
The traditional Chinese medicine composition comprises, by mass, 5-10 parts of white paeony root, preferably 5-8 parts of white paeony root, and more preferably 8 parts of white paeony root.
The traditional Chinese medicine composition comprises, by mass, 5-15 parts of liquorice, preferably 10-15 parts, and more preferably 10 parts.
In the invention, the mass parts of dandelion, fructus forsythiae, burdock, houttuynia cordata, cortex moutan, radix sophorae flavescentis, caulis polygoni multiflori, glossy privet fruit and Chinese yam are preferably higher than those of other medicines.
The Chinese yam, the liquorice and the white paeony root play the main roles of benefiting qi and nourishing blood together; herba Artemisiae Scopariae, bupleuri radix, semen plantaginis and Poria tablet are added to exert the effects of invigorating spleen and eliminating dampness; radix scrophulariae, radix Arnebiae, herba Houttuyniae, cortex moutan and radix Sophorae Flavescentis together have effects of clearing heat and cooling blood; the burdock, the weeping forsythia, the dandelion, the subprostrate sophora and the beautyberry leaf play the efficacies of clearing heat and removing toxicity together; caulis Polygoni Multiflori and fructus Ligustri Lucidi have effects of nourishing yin and invigorating kidney. The invention combines the medicines according to the proportion, combines the medicines together, emphasizes the prevention and treatment of diseases, effectively improves the immunity and the resistance of animals from various aspects, and has the effect of preventing and controlling African swine fever by combining with the disinfection of caustic soda solution and the disinfection of pigs by composite disinfectant.
The invention preferably also provides a preparation method of the traditional Chinese medicine composition in the scheme, which comprises the following steps:
pulverizing fructus Arctii, fructus forsythiae, herba Taraxaci, radix Sophorae Tonkinensis, folium Callicarpae Formosanae, herba Artemisiae Scopariae, bupleuri radix, semen plantaginis, Poria tablet, radix scrophulariae, radix Arnebiae, herba Houttuyniae, cortex moutan, radix Sophorae Flavescentis, caulis Polygoni Multiflori, fructus Ligustri Lucidi, rhizoma Dioscoreae, radix Paeoniae alba and Glycyrrhrizae radix to obtain Chinese medicinal composition. The traditional Chinese medicine composition in the embodiment of the application is obtained by adopting the preparation method.
In the present invention, the pulverization method is not particularly limited, and a pulverization method known to those skilled in the art may be used.
The African swine fever is caused by exogenous pathogenic heat, the excess pathogenic qi is exuberant, the healthy qi is not weakened, the healthy qi and the pathogenic factors are struggled against each other, the initial onset of the disease is characterized by intense struggle, and the excess heat syndrome occurs because the pathogenic heat from yang and the pathogenic factors from yang to yang. The excessive yang causes yin diseases, and the excessive yang in the middle and late stages consumes yin fluid of the body, which is converted into excessive heat and yin deficiency. The traditional Chinese medicine composition provided by the invention has the main effects of benefiting qi and nourishing blood, is supplemented with medicines for tonifying spleen and eliminating dampness, clearing heat and cooling blood, and nourishing yin and tonifying kidney, and has the effects of preventing and controlling African swine fever by being matched with the disinfection of caustic soda solution and the disinfection of pigs by a compound disinfectant.
In addition, when the traditional Chinese medicine composition is used for preventing and controlling the African swine fever, the independent use of auxiliary vital qi medicines such as qi tonifying and yang supporting medicines, such as ginseng, codonopsis pilosula, astragalus and the like, is not selected for prevention, and the independent auxiliary vital qi only can enable the vital qi and pathogenic factors to be more violent and the death to be quicker after the African swine fever is infected. The traditional Chinese medicine composition provided by the invention has the main effects of benefiting qi and nourishing blood, is supplemented with medicines for tonifying spleen and eliminating dampness, clearing heat and cooling blood, and nourishing yin and tonifying kidney, and has the effects of preventing and controlling African swine fever by being matched with the disinfection of caustic soda solution and the disinfection of pigs by a compound disinfectant.
Finally, a large amount of bitter and cold medicines are not suitable for preventing the African swine fever without the onset of disease, the medicines disturb yin and yang when pathogenic factors do not arrive at the stool, and are not desirable when the organism balance is broken, and the method is recorded as 'secret at the middle of yin and yang, and psychology treatment'. The traditional Chinese medicine composition provided by the invention has the main effects of benefiting qi and nourishing blood, is supplemented with medicines for tonifying spleen and eliminating dampness, clearing heat and cooling blood, and nourishing yin and tonifying kidney, and has the effects of preventing and controlling African swine fever by adjusting the balance of yin and yang and matching with the disinfection of caustic soda solution and the disinfection of pigs with compound disinfectant.
The Chinese yam, the liquorice and the white paeony root play the main roles of benefiting qi and nourishing blood together; herba Artemisiae Scopariae, bupleuri radix, semen plantaginis and Poria tablet are added to exert the effects of invigorating spleen and eliminating dampness; radix scrophulariae, radix Arnebiae, herba Houttuyniae, cortex moutan and radix Sophorae Flavescentis together have effects of clearing heat and cooling blood; the burdock, the weeping forsythia, the dandelion, the subprostrate sophora and the beautyberry leaf play the efficacies of clearing heat and removing toxicity together; caulis Polygoni Multiflori and fructus Ligustri Lucidi have effects of nourishing yin and invigorating kidney. The invention combines the medicines according to the proportion, combines the medicines together, emphasizes the prevention and treatment of diseases, effectively improves the immunity and disease resistance of animals from various aspects, and has the effect of preventing and controlling African swine fever by combining with the disinfection of caustic soda solution and the disinfection of pigs with compound disinfectant.
The traditional Chinese medicine composition and the traditional Chinese medicine feed provided by the invention are composed of feeding natural plant Chinese herbal medicines, are green and safe, meet the current national culture limit resistance, resistance reduction and resistance prohibition policies, and effectively replace the use of chemical medicines.
The traditional Chinese medicine formula improves the immunity and the resistance of live pigs by improving the environment in an organism, greatly reduces the infection probability and pressure by using strong alkali for disinfection in a large environment, avoids the protection of a biological membrane in a complex environment around the live pigs to pathogenic microorganisms by using a composite disinfectant compounded by glacial acetic acid, hydrogen peroxide and phosphoric acid for disinfection in a pigsty, avoids the harm of the disinfectant to the live pigs, has no pollution to the environment, changes the pH value of the disinfectant and uses oxides in a superposition way, furthest reduces the survival and reproduction possibility of the pathogenic microorganisms, can effectively prevent and control the occurrence of African swine fever, and has obvious effect; and the limitation is small, and the prevention and control cost is low.
The invention also provides application of the compound disinfectant in the scheme in preparation of drugs for preventing and controlling animal virulent infection.
In the present invention, the virulent infectious diseases preferably include porcine virulent infectious diseases; the porcine fulminating infection preferably comprises: one or more of swine fever, circovirus disease, foot and mouth disease, porcine reproductive and respiratory syndrome and epidemic diarrhea; the subject of said application preferably comprises a live pig. The method for preventing and controlling the African swine fever provided by the invention not only can effectively prevent and control the African swine fever, but also has good prevention and control effects on one or more severe infectious diseases in the swine fever, the ring disease, the foot and mouth disease, the blue ear disease and the epidemic diarrhea, and can reduce the prevention and control times of other severe diseases while preventing and controlling the African swine fever, thereby greatly reducing the prevention and control drug cost of swinery and improving the economic benefit.
In order to further illustrate the present invention, the method for controlling African swine fever and the application thereof provided by the present invention will be described in detail with reference to the following examples, which should not be construed as limiting the scope of the present invention.
Example 1
In a certain pig farm 1 in Hubei, 820 pigs are stored in a farm, 9-6 days in 2019, part of pigs only have the symptoms of fever, no eating and the like, a sick pig sample is collected for PCR detection, the detection result is positive African swine fever, 8-10 days, 820 sows in the whole farm are screened, the positive rate is 14%, positive individuals and peripheral individuals are eliminated, disinfectants such as glutaraldehyde and potassium dihydrogen sulfate are used for disinfection, the elimination treatment of the positive or inappetence-abnormal behavior pigs is found, the elimination treatment is reduced to 275 in 26 days in 9 months, and the prevention and control effect is not ideal.
9 months and 27 days, the rest herds are divided into three groups (original herds are not concentrated and are still in original piggeries, different groups of pigs are not in one piggery), and 90 groups are formed: 2 percent of caustic soda is used for disinfection twice a day according to the external environment of the pigsty; the pig house is disinfected with 3% glacial acetic acid (volume concentration), 0.81% hydrogen peroxide (volume concentration, diluted with 27% hydrogen peroxide), 0.1% phosphoric acid (volume concentration, easily diluted with 85% phosphoric acid) 5 times a day.
Two groups of 90: the pig basic feed is prepared by sterilizing the environment outside a pig house twice a day by using 2% of caustic soda, sterilizing the inside of the pig house by using glutaraldehyde and potassium dihydrogen sulfate disinfectants alternately twice a day respectively, and adding a traditional Chinese medicine composition (25 parts of burdock, 15 parts of fructus forsythiae, 15 parts of dandelion, 8 parts of vietnamese sophora root, 8 parts of beautyberry leaf, 8 parts of oriental wormwood, 8 parts of radix bupleuri, 10 parts of semen plantaginis, 10 parts of poria cocos, 8 parts of radix scrophulariae, 8 parts of lithospermum, 15 parts of houttuynia cordata, 15 parts of cortex moutan, 15 parts of radix sophorae flavescentis, 20 parts of caulis polygoni multiflori, 20 parts of glossy privet fruit, 20 parts of Chinese yam, 8 parts of radix paeoniae alba and 10 parts of liquorice).
Three groups of 95 heads: sterilizing with 1.0% caustic soda twice a day according to the environment outside the pigsty, sterilizing with pig 3 times a day with 2% glacial acetic acid (volume concentration) + 0.5% hydrogen peroxide (volume concentration, diluted with 27% hydrogen peroxide concentration) + 0.1% phosphoric acid (volume concentration, easily diluted with 85% phosphoric acid) in the pigsty; the pig basal feed is added with a traditional Chinese medicine composition (25 parts of burdock, 15 parts of fructus forsythiae, 15 parts of dandelion, 8 parts of subprostrate sophora, 8 parts of beautyberry leaves, 8 parts of oriental wormwood, 8 parts of radix bupleuri, 10 parts of semen plantaginis, 10 parts of poria cocos, 8 parts of radix scrophulariae, 8 parts of lithospermum, 15 parts of houttuynia cordata, 15 parts of cortex moutan, 15 parts of radix sophorae flavescentis, 20 parts of caulis polygoni multiflori, 20 parts of glossy privet fruit, 20 parts of Chinese yam, 8 parts of radix paeoniae alba and 10 parts of liquorice) according to a proportion of 1.0 percent of the total mass of.
After 10 months and 5 days, the positive rate and the incidence rate of each group of sow herds are reduced, an African swine fever virus positive sample cannot be detected in one group of environment and two groups of environment, and a small amount of samples in the second group of environment are detected to be positive (1.2%).
After 10 months and 10 days, the positive rate and the morbidity of each group of sow groups are obviously reduced, by 26 days in 10 months, 55 sows are reserved in one group, 65 sows are reserved in two groups, 76 sows are reserved in three groups, 196 sows are reserved in the other group, and all subsequent group-reserved sow groups are normally treated according to the technical scheme of the three groups, so that no positive or abnormal production condition occurs. The piglets born by the sows normally are negative in the whole fattening process and can be smoothly discharged, the sow herd in the current pig farm is enlarged to 553 pigs, the health condition of the pigherd is obviously improved, the immune procedure is continuously simplified, the immunity of highly pathogenic blue-ear disease and epidemic diarrhea is cancelled, and the diseases for reducing the immunity are as follows: the immunity times of the circovirus, the swine fever and the foot-and-mouth disease are respectively once, the positive rate of the whole virus of the highly pathogenic blue-ear disease, the epidemic diarrhea, the circovirus, the swine fever and the foot-and-mouth disease is detected to be reduced to 0.5 to 1.2 percent from 4.6 to 8.8 percent in the last year, the survival rate is improved to 96 percent from 92.7 percent in the last year in the whole process from delivery to slaughter, and the health care medicine cost of the pigs, such as vaccines, disinfection, medicines and the like, is reduced to 68 yuan from 200 yuan in the past to 68 yuan in the present (the reduction is 66 percent).
The results show that the prevention and control method has good prevention and control effect on the African swine fever, and the inhibition effect of the prevention and control method on the incidence rate of the African swine fever is obviously better than that of the prevention and control methods in one group or two groups.
Example 2
In a certain pig farm 2 in Hubei, 535 producing sows are produced, 11 months and 21 days in 2019, abnormal production is caused, partial pigs are fever and do not eat, a sick pig sample is collected for inspection, the PCR detection result is positive to African swine fever, the positive rate of the African swine fever detected in the whole field is 9.9%, 423 sows are left after all positive elimination treatment, and the 423 sows are left in 25 days in 11 months and begin to execute the following control scheme: 2% of caustic soda is used for disinfection twice a day according to the environment outside a pigsty, 3% of glacial acetic acid (volume concentration) + 0.8% of hydrogen peroxide (volume concentration, diluted by 27% of hydrogen peroxide) and 0.1% of phosphoric acid (volume concentration, easily diluted by 85% of phosphoric acid) are used for disinfection with pigs 3 times a day in the pigsty; the pig basal feed is added with a traditional Chinese medicine composition (25 parts of burdock, 15 parts of fructus forsythiae, 15 parts of dandelion, 8 parts of subprostrate sophora, 8 parts of beautyberry leaves, 8 parts of oriental wormwood, 8 parts of radix bupleuri, 10 parts of semen plantaginis, 10 parts of poria cocos, 8 parts of radix scrophulariae, 8 parts of lithospermum, 15 parts of houttuynia cordata, 15 parts of cortex moutan, 15 parts of radix sophorae flavescentis, 20 parts of caulis polygoni multiflori, 20 parts of glossy privet fruit, 20 parts of Chinese yam, 8 parts of radix paeoniae alba and 10 parts of liquorice) according to a proportion of 2.0 percent of the total mass of the basal feed, abnormal pigs are detected to be eliminated, 338 pigs are kept in 12 months and 12 days, and no. The main production performance is better than that of the prior year, and the survival rate of the whole pig farm is improved from 93.2 percent to 96.5 percent.
From the results, the method for preventing and controlling the African swine fever provided by the invention can effectively control the occurrence of the African swine fever, and has a remarkable effect.
Example 3
In the pig farm 1 described in example 1, in another 1 sow farm in the same area, 3000 pigs have fever, no food intake and other symptoms, a sick pig sample is collected for PCR detection, the detection result is negative in African swine fever, the environment outside the pig farm is strictly disinfected by 0.6% caustic soda 1 time a day in 11 months and 7 days in 2019, 1% glacial acetic acid (volume concentration) + 0.5% hydrogen peroxide (volume concentration, diluted by 27% hydrogen peroxide concentration) + 0.1% phosphoric acid (volume concentration, easily diluted by 85% phosphoric acid), and the pigs are disinfected 2 times a day; the pig basic feed is added with a traditional Chinese medicine composition (25 parts of burdock, 15 parts of fructus forsythiae, 15 parts of dandelion, 8 parts of subprostrate sophora, 8 parts of beautyberry leaves, 8 parts of oriental wormwood, 8 parts of radix bupleuri, 10 parts of semen plantaginis, 10 parts of poria cocos, 8 parts of radix scrophulariae, 8 parts of lithospermum, 15 parts of houttuynia cordata, 15 parts of cortex moutan, 15 parts of radix sophorae flavescentis, 20 parts of caulis polygoni multiflori, 20 parts of glossy privet fruit, 20 parts of Chinese yam, 8 parts of radix paeoniae alba and 10 parts of liquorice) according to a proportion of 1.0% of the total mass of the basic feed, and no African swine fever occurs.
The results show that the composite disinfectant provided by the invention can effectively prevent the occurrence of African swine fever and has a remarkable effect.
Comparative example 1
Before and after 7 months in 2019, a plurality of pig farms in the same area of the pig farm 1 in the example 1 are applied, caustic soda is used for environment disinfection, and potassium dihydrogen persulfate drinking water, citric acid drinking water and other prevention and control schemes are used in a pig house, so that positive individuals and suspicious individuals on the periphery are eliminated, pig groups are completely eliminated after two months, the pig farm is emptied, and the disinfectant of the two pig farms is used for about millions of yuan. The swinery of 90% or more of the swineries with different scales in the same area is completely eliminated, the swinery is emptied, and the capacity is not recovered to 30% by 4 months in 2020.
As can be seen from examples 1-3 and comparative example 1, the method for preventing and controlling African swine fever provided by the invention can effectively control the occurrence of African swine fever, can also prevent the occurrence of African swine fever, and has obvious effect; and the limitation is small, and the prevention and control cost is low.
The composite disinfectant provided by the invention can effectively prevent and control African swine fever, has a good prevention and control effect on one or more severe infectious diseases in swine fever, ring disease, foot and mouth disease, blue ear disease and epidemic diarrhea, and can reduce the prevention and control times of other severe diseases while preventing and controlling African swine fever, thereby greatly reducing the prevention and control drug cost of swinery and improving the economic benefit.
Although the present invention has been described in detail with reference to the above embodiments, it is only a part of the embodiments of the present invention, not all of the embodiments, and other embodiments can be obtained without inventive step according to the embodiments, and the embodiments are within the scope of the present invention.
Claims (7)
1. The method for preventing and controlling African swine fever is characterized by comprising the following steps:
adopting caustic soda solution to disinfect the periphery of the pigsty;
disinfecting the pigs by adopting a compound disinfectant; the composite disinfectant comprises 1-3% of glacial acetic acid, 0.135-0.81% of hydrogen peroxide, 0.1% of phosphoric acid and the balance of water by volume concentration percentage;
feeding traditional Chinese medicine feed; the traditional Chinese medicine feed comprises a traditional Chinese medicine composition and a basic feed; the mass ratio of the traditional Chinese medicine composition to the basic feed is (0.5-2): 100, respectively; the traditional Chinese medicine composition comprises the following raw materials in parts by mass: 5-35 parts of burdock, 10-25 parts of fructus forsythiae, 5-20 parts of dandelion, 5-10 parts of subprostrate sophora, 5-10 parts of folium phyllanthi, 5-10 parts of oriental wormwood, 5-10 parts of radix bupleuri, 5-15 parts of semen plantaginis, 5-15 parts of poria cocos slice, 5-10 parts of radix scrophulariae, 5-10 parts of lithospermum, 5-20 parts of houttuynia cordata, 5-22 parts of cortex moutan, 5-20 parts of radix sophorae flavescentis, 5-25 parts of caulis polygoni multiflori, 5-25 parts of glossy privet fruit, 10-25 parts of Chinese yam, 5-10 parts of radix paeoniae alba and 5-15 parts of liquorice.
2. The method for controlling African swine fever according to claim 1, wherein the method for controlling African swine fever comprises prevention and control; when the African swine fever is prevented, the prevention opportunity is when epidemic situation does not occur or after an individual with abnormal epidemic situation elimination occurs; when the African swine fever control is carried out, the control is carried out at the moment that the abnormal pigs are still positive by adopting PCR detection after prevention.
3. The method for controlling African swine fever according to claim 2, wherein the prevention is carried out by: the composite disinfectant comprises 1 percent of glacial acetic acid, 2 percent of glacial acetic acid, 0.135 percent of hydrogen peroxide, 0.81 percent of phosphoric acid and the balance of water according to volume concentration percentage;
the dosage of the disinfectant is 50-100 ml/m2(ii) a The disinfection frequency is 1-2 times/d;
the mass concentration of the caustic soda is 0.5 percent and 1.0 percent, and the dosage of the caustic soda solution is 50-100 ml/m2(ii) a The disinfection frequency is 1 time/d;
the mass ratio of the traditional Chinese medicine composition to the basic feed is (0.5, 1.5): 100.
4. the method for controlling African swine fever according to claim 3, wherein the controlling is carried out by: the composite disinfectant comprises glacial acetic acid (2%, 3%), hydrogen peroxide (0.6%, 0.81%), phosphoric acid (0.1%) and water (the balance) by volume concentration percentage;
the dosage of the disinfectant is 100ml/m2(ii) a The disinfection frequency is 3-5 times/d;
the mass concentration of the caustic soda is 1 percent and 2 percent]The amount of the caustic soda solution is 100ml/m2(ii) a The disinfection frequency is 1-2 times/d; (when the caustic soda is over 2.0%, the harm to disinfection equipment is large, and is generally not over 2.0%)
The mass ratio of the traditional Chinese medicine composition to the basic feed is [1.5,2 ]: 100.
5. the method for controlling African swine fever according to claim 3 or 4, further comprising: and (3) carrying out full-group quantitative PCR detection every 3-5 days from the beginning of control, and removing positive individuals and fever individuals.
6. The method for preventing and controlling African swine fever according to any one of claims 1-5, wherein the method is used for preventing and controlling animal virulent infectious diseases.
7. The use of claim 6, wherein said animal virulent infectious disease comprises one or more of hog cholera, circovirus, foot-and-mouth disease, porcine reproductive and respiratory disease, and epidemic diarrhea.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113317225A (en) * | 2021-05-31 | 2021-08-31 | 广州朴成生物科技有限公司 | Prevention and control method for African swine fever |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101554414A (en) * | 2008-04-09 | 2009-10-14 | 北京大北农动物保健科技有限责任公司 | Traditional Chinese medicine mixture for treating livestock and poultry virosis and preparation method thereof |
| CN103202294A (en) * | 2013-04-25 | 2013-07-17 | 广州迈高化学有限公司 | Disinfectant |
| CN109924213A (en) * | 2017-12-16 | 2019-06-25 | 常州普纳电子科技有限公司 | A kind of sanitizer formulations |
| CN110898126A (en) * | 2019-11-26 | 2020-03-24 | 陈俢龙 | Traditional Chinese medicine composition, preparation method and application thereof |
-
2020
- 2020-12-08 CN CN202011442555.3A patent/CN112586441A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101554414A (en) * | 2008-04-09 | 2009-10-14 | 北京大北农动物保健科技有限责任公司 | Traditional Chinese medicine mixture for treating livestock and poultry virosis and preparation method thereof |
| CN103202294A (en) * | 2013-04-25 | 2013-07-17 | 广州迈高化学有限公司 | Disinfectant |
| CN109924213A (en) * | 2017-12-16 | 2019-06-25 | 常州普纳电子科技有限公司 | A kind of sanitizer formulations |
| CN110898126A (en) * | 2019-11-26 | 2020-03-24 | 陈俢龙 | Traditional Chinese medicine composition, preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 冯三祥，等: "过氧乙酸的配制及稳定性观察报告", 《宁夏医学杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113317225A (en) * | 2021-05-31 | 2021-08-31 | 广州朴成生物科技有限公司 | Prevention and control method for African swine fever |
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