CN109106806A - A kind of women secret nursing washing lotion and preparation method thereof - Google Patents

A kind of women secret nursing washing lotion and preparation method thereof Download PDF

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Publication number
CN109106806A
CN109106806A CN201810634009.6A CN201810634009A CN109106806A CN 109106806 A CN109106806 A CN 109106806A CN 201810634009 A CN201810634009 A CN 201810634009A CN 109106806 A CN109106806 A CN 109106806A
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CN
China
Prior art keywords
women
extract
washing lotion
secret
nursing washing
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Pending
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CN201810634009.6A
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Chinese (zh)
Inventor
张静
吴美音
郑亚美
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Guangzhou Yun Yun Medicine Polytron Technologies Inc
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Guangzhou Yun Yun Medicine Polytron Technologies Inc
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Priority to CN201810634009.6A priority Critical patent/CN109106806A/en
Publication of CN109106806A publication Critical patent/CN109106806A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Abstract

The present invention provides a kind of women secret nursing washing lotion and preparation method thereof, belongs to daily personal care product scope;The Feminine care lotion contains unique CPS care formula, and main composition is lactic acid bacteria, big fruit blueberry berry extract, Seabuckthorm Seed Oil, lycium ruthenicum extract, raspberry extract and red pomegranate extract;Present invention is mainly used for the cleaning of women private parts, antibacterial, anti-inflammatory, antiviral, raising private parts skin immunity, care secret health;Product is weakly acidic simultaneously, pH 4.5, coincide with female vulva pH, mildly non-stimulated to skin.

Description

A kind of women secret nursing washing lotion and preparation method thereof
Technical field
The present invention relates to a kind of novel women secrets to nurse washing lotion, belongs to personal feminine hygiene articles field.
Background technique
In recent years, the secret nursing of women is more and more widely paid close attention to health.According to investigations the results show that having up to 91% women by include secretion it is unclean, it is bored itch, the puzzlement of privates discomfort such as peculiar smell, especially in day heat (46%), menstrual period (43%), office's sitting (30%) and intimate front and back (29%) are easy to appear discomfort.Human papilloma virus (HPV) infection is to cause The HPV infection rate of the main factor of cervical carcinoma, current China women is about 16.8%, and in healthy women crowd, HPV's Infection rate generally 13.5% or so, has the women of 70-80% at least to infect a HPV in all one's life, since HPV infection rate is more general Time, intimate contact, mediate contact all may cause infection HPV, therefore women should pay attention to secret cleaning and protection in daily life.
In terms of daily nursing, more and more women selections use conditioning liquid, at present women secret nursing on the market Washing lotion mainly has the medicinal lotion with disease treatment effect and the general duty nursing liquid with cleaning, biocidal efficacies, medicinal lotion It is mainly used for treating various gynecological diseases, general duty nursing washing lotion major function then concentrates on cleaning and sterilization;For general duty nursing Washing lotion, if biocidal efficacies are too strong or the excessive industrial chemicals of addition seriously destroys beneficial bacterium while easily leading to killing harmful bacteria Proliferation, and then the normal pH of private parts is destroyed, lead to Flora Disturbance, it is serious to reduce body self purification.How a kind of peace is provided Quan Xinggao, good product effect women secret nursing washing lotion be one of this field urgent problem to be solved.
Summary of the invention
The purpose of the present invention is starting with from Tiny ecosystem angle, a kind of women secret nursing washing lotion is provided, can effectively be pressed down The proliferation of staphylococcus aureus processed, Escherichia coli and Candida albicans adjusts the increasing of women private parts beneficial bacterium lactobacillus It grows, maintains the normal pH of private parts, adjust colony balance, improve body self-cleaning and immune function, prevent virus infection, make simultaneously The salubrious state of privates holding free from extraneous odour.
The present invention is achieved through the following technical solutions:
A kind of women secret nurses washing lotion, containing the antibacterial formula of unique CPS, main composition by mass percentage, by Following raw material is made: Cranberry extract 5%, lycium ruthenicum extract 3%, raspberry extract 5%, red pomegranate extract 2%, sea-buckthorn Seed oil 4%, lactic acid bacteria 0.5%;Increase the moistening effect of product with a certain amount of butanediol (about 8%) simultaneously, is formulated selected table The sodium methyl cocoyl taurate that face activating agent and emulsifier are 8%, pH adjusting agent are lactic acid (additive amount about 3%).
As the technical solution of present invention further optimization, a kind of novel women secret nurses washing lotion, special The main composition of some antibacterial formulas of CPS is prepared from the following raw materials by mass percentage: Cranberry extract 5-7%, Lycium ruthenicum extract 3-5%, raspberry extract 5-7%, red pomegranate extract 2-5%, Seabuckthorm Seed Oil 4-9%, lactic acid bacteria 0.5-1%;
Preferably, the pH value of the women secret nursing washing lotion is 4.5.
In prescription of the present invention, lactic acid bacteria can effectively reduce the mistake of staphylococcus aureus, Candida albicans and Escherichia coli Degree breeding, improves secret immune function;Cranberry is North America small berries, is known as " North America ruby ", rich in a variety of former cyanine Element, while Official US's pharmacopeia USP is recorded, Cranberry has effects that prevent urethra, vaginal bacterial infection;Lycium ruthenicum is referred to as " soft gold " is known as the title of " king of anthocyanidin ", is the highest natural fruits of procyanidin content found so far, multi-section Ancient books, which records it, has adjusting female irregular menstruation, menopause, soreness and weakness of waist and knees and other effects;In red raspberry fruits, content of vitamin E is occupied It first of all kinds of fruit, is known as the title of " king of third generation gold fruit ", while being rich in " ellagic acid " abundant in red raspberry fruits, The study found that ellagic acid all has preferable protective effect to colon, uterine neck;Contain special pomegranate root skin in red pomegranate fruit Alkali has good inhibiting effect to staphylococcus aureus and a variety of dermatophytes, while red pomegranate fruit is rich in polyphenol and flower Green element, can improve skin antioxidant effect and immune function;Seabuckthorm Seed Oil is rich in flavones, organic acid, alkaloid, sterols, three 140 various bioactive components such as terpenes and various vitamins, anti-infection effect is stronger, can promote wound healing, wide It is general for burning, scalding, frostbite etc., the osajin in Seabuckthorm Seed Oil has oestrogen-like hormone ingredient, can make vagina epithelium Hyperplasia and angling;A large amount of neutraceutical active ingredients in sea-buckthorn can provide nutrition for Vaginal lactobacilli, and Bacillus acidi lactici is promoted to increase It grows, makes vagina in acidity, keep the effect for killing pathogen, while a large amount of clinical study results show based on Seabuckthorm Seed Oil Want the compound external-use preparation of ingredient that there is preferable therapeutic effect to high-risk HPV cervical infection, total effective rate can achieve 80% More than, make HPV negative conversion rate up to 50% or more.
The present invention also provides a kind of preparation methods of above-mentioned women secret nursing washing lotion, it is characterised in that including as follows Step:
(1) 4 parts of Cranberry extract are weighed, it is 3 parts of lycium ruthenicum extract, 3 parts of raspberry extract, 4 parts of red pomegranate extract, husky 1 part of oil of spine seed, 0.5 part of lactic acid bacteria, 15 parts of sodium methyl cocoyl taurate, 14 parts of butanediol, 3 parts of lactic acid, preservative benzene oxygen 0.01 part of ethyl alcohol.
(2) first sodium methyl cocoyl taurate is added in blender, deionized water is then added, heats while stirring To 75 °C, butanediol and Seabuckthorm Seed Oil are added after making it completely dissolved, stirs and naturally cools to 35 °C.
(3) by Cranberry extract, black fruit fructus lycii extract, raspberry extract, red pomegranate extract, lactic acid bacteria, benzene Oxyethanol is added in above-mentioned material, stirs evenly.
(4) Material pH to pH4.5 is adjusted with lactic acid, the metering packing that sterilizes after mixing evenly is up to this product.
Advantages of the present invention:
The present invention adjusts women private parts colony balance with lactic acid bacteria, stablizes pH, improves private parts skin immune function controlling, Effectively inhibit the invasion of harmful bacteria;Addition simultaneously is rich in procyanidine plant extracts: Cranberry extract, lycium ruthenicum are extracted Object, raspberry extract, red pomegranate extract, raising secret skin is anti-oxidant and immune function, addition Seabuckthorm Seed Oil improve it Antibacterial, resists the effect of poisoning intrusion at anti-inflammatory;Each component is synergistic, and it is daily that the nursing washing lotion being prepared is suitable for women Secret nursing, Product Safety is high, can effectively promote the proliferation of women private parts beneficial bacterium lactobacillus, inhibit harmful bacteria Excessive multiplication balances private parts flora, improves private parts skin immunity, makes the salubrious free from extraneous odour of privates;Product is in simultaneously Faintly acid is coincide with women secret pH, mildly non-stimulated to skin, is more advantageous to women's health.
Specific embodiment:
Form is described further a specific embodiment of the invention by the following examples, but should not be interpreted as this The range of above content of the present invention is only limitted to following example, and all technologies realized based on above content of the present invention belong to this hair Bright range.
Lactic acid bacteria is purchased from Guangzhou Jin Sheng Biotechnology Co., Ltd;Cranberry extract, lycium ruthenicum extract, raspberry Extract, red pomegranate extract and Seabuckthorm Seed Oil are purchased from Beijing Brilliance Biochemical Co., Ltd..
Embodiment:
Preparation method:
(1) according to specific implementation case, Cranberry extract, lycium ruthenicum extract, raspberry extract, red pomegranate are accurately weighed Extract, lactic acid bacteria, Seabuckthorm Seed Oil, sodium methyl cocoyl taurate, butanediol, lactic acid, preservative Phenoxyethanol are each appropriate.
(2) first sodium methyl cocoyl taurate is added in blender, deionized water is then added, heats while stirring To 75 °C, butanediol and Seabuckthorm Seed Oil are added after making it completely dissolved, 35 °C are naturally cooled to after stirring.
(3) by Cranberry extract, lycium ruthenicum extract, raspberry extract, red pomegranate extract, lactic acid bacteria, benzene oxygen Ethyl alcohol is added in above-mentioned material, stirs evenly.
(4) Material pH to pH4.5 is adjusted with lactic acid, the metering packing that sterilizes after mixing evenly is up to this product.
Above-described embodiment 1-3 feminine wash is carried out assessment on probation, using effect is as follows: each group number on probation is no less than 30 people after continuous use 30 days, assess its cleaning effect, moist degree, antipruritic and taste removal effect, assessment result such as following table It is shown:
1. 2. number 3. test item 4. cleaning effect is good 5. cleaning effect is general 6. there is no cleaning effect
7. embodiment 1 8. 30 9. nursing washing lotion 10. 30 11. 0 12. 0
13. embodiment 2 14. 30 15. nursing washing lotion 16. 30 17. 0 18. 0
19. embodiment 3 20. 30 21. nursing washing lotion 22. 29 23. 1 24. 0
25. blank 26. 30 27. clear water 28. 5 29. 10 30. 15
31. 32. number 33. test item 34. antipruritic, taste removal effect Fruit is good 35. antipruritic, taste removal effect Fruit is general 36. without not antipruritic and Taste removal effect
37. embodiment 1 38. 30 39. nursing washing lotion 40. 28 41. 3 42. 1
43. embodiment 2 44. 30 45. nursing washing lotion 46. 25 47. 3 48. 2
49. embodiment 3 50. 30 51. nursing washing lotion 52. 26 53. 2 54. 2
55. blank 56. 30 57. clear water 58. 0 59. 1 60. 29

Claims (9)

1. the present invention provides a kind of women secret nursing washing lotion and preparation method thereof, the Feminine care lotion contains unique CPS care formula, contains procyanidine abundant, there is a stronger free radical scavenging activity: main composition be lactic acid bacteria, it is climing more Certain kind of berries extract, Seabuckthorm Seed Oil, lycium ruthenicum extract, raspberry extract and red pomegranate extract;Present invention is mainly used for women It is private parts cleaning, antibacterial, anti-inflammatory, antiviral, the proliferation of women private parts beneficial bacterium lactic acid bacteria can be effectively promoted, is inhibited The excessive multiplication of harmful bacteria Escherichia coli, staphylococcus aureus, Candida albicans etc. improves private parts skin immunity, Take good care of secret health;Product is weakly acidic simultaneously, pH 4.5, coincide with female vulva pH, mildly non-stimulated to skin, more favorably In women's health.
2. a kind of women secret nurses washing lotion, take good care of and be formulated containing unique CPS, which is characterized in that be prepared from the following raw materials: planting Object extract 13-33%, Seabuckthorm Seed Oil 3-5%, lactic acid bacteria 0.5-1.0%;The surfactant of the nursing washing lotion and emulsification simultaneously Agent additive amount is 7-10%, and moisturizer 5-10%, pH adjusting agent 0.5-3%, preservative 0.003-0.01%, remaining is supplemented with water.
3. nursing washing lotion by women secret described in claim 1, it is characterised in that the plant extracts is with quality percentage Than the Cranberry extract 5-10% of meter, lycium ruthenicum extract 3-8%, raspberry extract 4-10%, red pomegranate extract 1-5%.
4. nursing washing lotion by women secret described in claim 1, it is characterised in that the surfactant and emulsifier be with The sodium methyl cocoyl taurate of the 7-10% of mass percent meter.
5. nursing washing lotion by women secret described in claim 1, it is characterised in that the moisturizer is by percentage to the quality 5-10% butanediol.
6. nursing washing lotion by women secret described in claim 1, it is characterised in that the pH adjusting agent is with mass percent The lactic acid of the 0.5-3% of meter.
7. nursing washing lotion by women secret described in claim 1, it is characterised in that the preservative is by percentage to the quality 0.003-0.01% Phenoxyethanol.
8. a kind of novel women secret nursing washing lotion described in -6 according to claim 1, which is characterized in that the novel women is private The pH value of close nursing washing lotion is 4.5.
9. a kind of dosage form of the described in any item women secret nursing washing lotions of claim 1-7 is mousse foam type.
CN201810634009.6A 2018-06-20 2018-06-20 A kind of women secret nursing washing lotion and preparation method thereof Pending CN109106806A (en)

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CN110051618A (en) * 2019-05-16 2019-07-26 上海复沣生物科技有限公司 A kind of microecological balance care composition and product
CN110201150A (en) * 2019-07-12 2019-09-06 广州莎蔓生物科技有限公司 A kind of drug increasing the anti-HPV of human body cell activity
CN111053870A (en) * 2019-12-30 2020-04-24 广州宏众生物科技有限公司 Natural composition extracting solution for female privacy care and preparation method thereof
CN111568785A (en) * 2020-06-17 2020-08-25 西安贝迪斯可生物科技有限公司 Female private part care solution with antioxidant effect and preparation method thereof
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
US11110049B2 (en) 2017-06-23 2021-09-07 The Procter & Gamble Company Composition and method for improving the appearance of skin
CN114344192A (en) * 2022-01-24 2022-04-15 耀然实业股份有限公司 Personal care composition, personal care product and personal care product
US11583488B2 (en) 2020-06-01 2023-02-21 The Procter & Gamble Company Method of improving penetration of a vitamin B3 compound into skin
US11622963B2 (en) 2018-07-03 2023-04-11 The Procter & Gamble Company Method of treating a skin condition

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11110049B2 (en) 2017-06-23 2021-09-07 The Procter & Gamble Company Composition and method for improving the appearance of skin
US11622963B2 (en) 2018-07-03 2023-04-11 The Procter & Gamble Company Method of treating a skin condition
CN110051618A (en) * 2019-05-16 2019-07-26 上海复沣生物科技有限公司 A kind of microecological balance care composition and product
CN110201150A (en) * 2019-07-12 2019-09-06 广州莎蔓生物科技有限公司 A kind of drug increasing the anti-HPV of human body cell activity
CN111053870A (en) * 2019-12-30 2020-04-24 广州宏众生物科技有限公司 Natural composition extracting solution for female privacy care and preparation method thereof
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
US11583488B2 (en) 2020-06-01 2023-02-21 The Procter & Gamble Company Method of improving penetration of a vitamin B3 compound into skin
US11911498B2 (en) 2020-06-01 2024-02-27 The Procter & Gamble Company Low pH skin care composition and methods of using the same
CN111568785A (en) * 2020-06-17 2020-08-25 西安贝迪斯可生物科技有限公司 Female private part care solution with antioxidant effect and preparation method thereof
CN111568785B (en) * 2020-06-17 2022-07-26 西安贝迪斯可生物科技有限公司 Female private part care solution with antioxidant effect and preparation method thereof
CN114344192A (en) * 2022-01-24 2022-04-15 耀然实业股份有限公司 Personal care composition, personal care product and personal care product

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Application publication date: 20190101