CN106466454A - A kind of prevention and the gel for the treatment of gynecological inflammation - Google Patents
A kind of prevention and the gel for the treatment of gynecological inflammation Download PDFInfo
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- CN106466454A CN106466454A CN201510514713.4A CN201510514713A CN106466454A CN 106466454 A CN106466454 A CN 106466454A CN 201510514713 A CN201510514713 A CN 201510514713A CN 106466454 A CN106466454 A CN 106466454A
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Abstract
A kind of prevention and the gel for the treatment of gynecological inflammation, the raw material making described gel effective ingredient consists of:Hydroxyethyl cellulose, Cortex Phellodendri, Fructus Cnidii, the Radix Stemonae, matrine, chlorhexidine acetate, Mentholum, Borneolum Syntheticum.Chinese medicine, chemicalses are combined by the present invention, Synergistic, there is quick suppression, kill the pathogenic microorganism such as staphylococcus aureuses, mycete, bacillus pyocyaneus, simultaneously to cervical erosion, leucorrhea with red and white discharge, the female chronic inflammation such as trichomonal vaginitis and vagina fungal infection is evident in efficacy.
Description
Technical field
The present invention relates to Chinese medicine health field and in particular to a kind of prevention and treatment gynecological inflammation gel.
Background technology
Gynecological inflammation is women common disease, is primarily referred to as the inflammation of female sex organ, specifically includes female vulva inflammation, vaginitiss, cervix uteri
Scorching, pelvic inflammatory disease.Infusorian, mycete and all kinds of pathogenic infection, lead to body inflammation, and body part resistances against diseases decline.
At present on the market, prevention and treatment gynecological inflammation medicine are more, but there is problems with:1. curative effect is more single;2. it is directed to gynecological scorching
Drugs on patients's reproductive tract environment of disease and the generation of mucosa itself secretory function destruction to a certain extent, local immunity power declines, and pathogenic bacterium produce
Drug resistance is so that inflammation recurrent exerbation;3. medicine stability is poor, and action time is short, and curative effect is slower.How to solve above-mentioned technical deficiency, become
Problem demanding prompt solution.
Content of the invention
The present invention provide a kind of prevention and treatment gynecological inflammation gel, with solve existing for gynecological inflammation curative effect of medication single, destroy life
Grow environment and mucosa itself secretory function, inflammation recurrent exerbation, medicine stability be poor, slow curative effect problem.
For reaching above-mentioned purpose, the technical solution used in the present invention is:
A kind of prevention and treatment gynecological inflammation gel it is characterised in that:Described gel is with hydroxyethyl cellulose as adhesive agent, slow-released carrier,
Matrine, chlorhexidine acetate, Fructus Cnidii, the Radix Stemonae, Cortex Phellodendri Synergistic.
The pharmacology analysis of each herbal medicine of the present invention are as follows:
Chlorhexidine acetate:Cidex-7, wishes to part staphylococcuses, Streptococcus mutans, streptococcus salivariuss, Candida albicans, large intestine angstrom
Bacterium, anaerobism bacterium acidi propionici are in extremely sensitive.
Matrine:For infusorian or monilial vaginitises, chronic cervicitiss, also can be used for senile vaginitiss, pelvic inflammatory disease etc..
Cortex Phellodendri:Antibacterial, heat clearing away, pathogenic fire purging, reducing the asthenic fever.
Fructus Cnidii:Removing dampness and killing parasites, wind-dispelling.
The Radix Stemonae:Antibacterial, parasite killing.
Hydroxyethyl cellulose:Adhesive agent, slow releasing carrier of medication.
Borneolum Syntheticum:Sensory nerve there is is minimal irritation act on, and there is refrigerant, itching-relieving action, and have and make local assume gentle pain relieving and detumescence
Some antibacterials are also had suppression and killing action with funguses by effect.
Mentholum:Excitantss, act on skin and mucosa, have refrigerant itching-relieving action.
PH adjusting agent:Cidex-7, and regulating drug pH, maintain medicine stability, maintain reproductive tract environment and mucosa itself secretion work(
Energy.
A kind of prevention and the gel for the treatment of gynecological inflammation, are mainly made up of following raw material, with weight ratio meter are:
Chlorhexidine acetate 0.05%~3.0%, matrine 0.5%~5.0%, Cortex Phellodendri 1.0%~5.0%, Fructus Cnidii 1.0%~5.0%, the Radix Stemonae 1.0%~
5.0%th, hydroxyethyl cellulose 0.2%~3.0%, Borneolum Syntheticum 0.04%~3.5%, Mentholum 0.04%~1.0%, pH adjusting agent 0~5.0%.
A kind of prevention and treatment gynecological inflammation gel preparation method it is characterised in that:Comprise the following steps that:
Take Fructus Cnidii, Cortex Phellodendri, Radix Stemonae decontamination to clean, dry, be placed in container, add the purified water of 5~10 times amount, soak 1~2 little
When, heated and boiled 1~2 hour, filter, medicinal residues repeat the above steps, merge filtrate twice, standby.
Borneolum Syntheticum, Mentholum are dissolved with a small amount of ethanol, adds above-mentioned middle drug filtrate, sequentially add chlorhexidine acetate, matrine, standby.
Take appropriate purified water, be heated to 70 DEG C~90 DEG C, add hydroxyethyl cellulose, be sufficiently stirred for.When solution is cooled to 50 DEG C~70 DEG C,
Add resulting solution in (2), be sufficiently stirred for, obtain rufous or brown yellow gel.With acetic acid or hydrochloric acid or lactic acid, adjust pH to 3.5~5.5,
It is the gel of described treatment gynecological inflammation.
The present invention wound no any to human body, non-stimulated, no hormone, without any side effects on the premise of, Chinese medicine ingredients and chemical drugss
Multipath suppression virus and the activity of antibacterial, instant effect, have good stability;And action time is longer, nourishes and repair sexual cell, improve itself
Secretory function and local immunity power.Thus realizing to the prevention of multiple gynecological chronic inflammatory disease, treatment, conditioning, it is the solution that patient provides better and safer
Certainly method.
Specific embodiment
Below the present invention is described in further detail, but it should illustrating, protection scope of the present invention is not limited only to this.
Embodiment one:
A kind of prevention and the gel for the treatment of gynecological inflammation, are mainly made up of following raw material, with weight ratio meter are:Chlorhexidine acetate 0.05g, hardship
Ginseng alkali 2.0g, Cortex Phellodendri 2.0g, Fructus Cnidii 3.0g, Radix Stemonae 3.0g, hydroxyethyl cellulose 1.1g, Borneolum Syntheticum 1.5g, Mentholum 0.04g, pH adjust
Section agent (lactic acid) is appropriate, add water to 100.0g.
Preparation method:
Take Fructus Cnidii, Cortex Phellodendri, Radix Stemonae decontamination to clean, dry, be placed in container, add the purified water of 5~10 times amount, soak 1~2 little
When, heated and boiled 1~2 hour, filter, medicinal residues repeat the above steps, merge filtrate twice, standby.
Borneolum Syntheticum, Mentholum are dissolved with a small amount of ethanol, add above-mentioned middle drug filtrate, sequentially add chlorhexidine acetate, matrine, obtain A liquid,
Standby.
Take appropriate purified water, be heated to 70 DEG C~90 DEG C, add hydroxyethyl cellulose, be sufficiently stirred for, obtain B liquid.
When B liquid is cooled to 50 DEG C~70 DEG C, A, B liquid is mixed, is sufficiently stirred for, obtains rufous or brown yellow gel.
With pH adjusting agent breast acid for adjusting pH to 3.5~5.5, the gel of as described treatment gynecological inflammation.
Using method:
Cleaning medicine-feeding part, the gynecological gel of the present embodiment is applied to patient's pudendum or vagina, acts on 5~10 minutes.
Embodiment two:
A kind of prevention and the gel for the treatment of gynecological inflammation, are mainly made up of following raw material, with weight ratio meter are:Chlorhexidine acetate 0.10g, hardship
Ginseng alkali 1.0g, Cortex Phellodendri 5.0g, Fructus Cnidii 5.0g, Radix Stemonae 5.0g, hydroxyethyl cellulose 1.1g, Borneolum Syntheticum 0.5g, Mentholum 0.08g, pH adjust
Section agent (acetic acid) is appropriate, add water to 100.0g.
Preparation method and using method, with embodiment one.
Although describing multiple case study on implementation of the present invention, those skilled in the art can make respectively within scope
Plant deformation or change, as long as less than the protection domain described by claim of the present invention, all should be within protection scope of the present invention.
Claims (5)
1. a kind of prevention and treatment gynecological inflammation gel it is characterised in that by chlorhexidine acetate, matrine, Cortex Phellodendri, Fructus Cnidii,
The Radix Stemonae uses cooperatively, Synergistic;And with hydroxyethyl cellulose as adhesive agent, slow-released carrier, add Borneolum Syntheticum, Mentholum to make
Gel, its composition of raw materials is as follows:
2. the gel of a kind of prevention according to claim 1 and treatment gynecological inflammation is it is characterised in that described adhesive agent, slow release
Carrier is hydroxyethyl cellulose, Hypromellose, methylcellulose, Carbomer one of which or two kinds of things mixed above, energy
Make gel stick to inflammatory tissue position, and make sustained drug act on inflammatory tissue position.
3. according to claim 1 a kind of prevention and treatment gynecological inflammation gel it is characterised in that by Chinese medicine ingredients (Cortex Phellodendri,
Fructus Cnidii, the Radix Stemonae) it is combined with chlorhexidine acetate, matrine, Synergistic.
4. according to a kind of prevention described in claim 1 and treatment gynecological inflammation gel it is characterised in that with acetic acid, hydrochloric acid, lactic acid,
One of citric acid, phosphoric acid, adjust pH to 3.5~5.5, strengthen medicine stability, maintain reproductive tract environment and mucosa
Itself secretory function.
5. according to claim 1 a kind of prevention and treatment gynecological inflammation gel preparation method it is characterised in that:Including
Following processing step:
(1) take Fructus Cnidii, Cortex Phellodendri, Radix Stemonae decontamination to clean, dry, be placed in container, add the purified water of 5~10 times amount, leaching
Bubble 1~2 hour, heated and boiled 1~2 hour, filter, medicinal residues repeat the above steps, merge filtrate twice, standby.
(2) Borneolum Syntheticum, Mentholum are dissolved with a small amount of ethanol, add above-mentioned middle drug filtrate, sequentially add chlorhexidine acetate, matrine,
Standby.
(3) take appropriate purified water, be heated to 70 DEG C~90 DEG C, add hydroxyethyl cellulose, be sufficiently stirred for.Treat solution be cooled to 50 DEG C~
When 70 DEG C, add resulting solution in (2), be sufficiently stirred for, obtain rufous or brown yellow gel.
(4) use acetic acid or hydrochloric acid or lactic acid, adjust pH to 3.5~5.5, the gel of as described treatment gynecological inflammation.
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Cited By (12)
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CN107661494A (en) * | 2017-11-20 | 2018-02-06 | 方晓东 | It is a kind of to be used for gynaecological imflammation, the Chinese medicine composition gel of koro and its production technology |
CN107812137A (en) * | 2017-10-25 | 2018-03-20 | 北京中蜜科技发展有限公司 | A kind of draft skin bacteriostatic gel of propolis-containing and preparation method thereof |
CN108452295A (en) * | 2018-03-28 | 2018-08-28 | 丹东欣时代生物医药科技有限公司 | A kind of compact gel and preparation method antibacterial, that adjust microecological balance |
CN108721544A (en) * | 2018-04-25 | 2018-11-02 | 四川生命源健康管理有限公司 | The externally-applied female of anticancer function is sprayed |
CN108785680A (en) * | 2018-07-10 | 2018-11-13 | 杨先锋 | It is a kind of to be applied using the gel of biomass through pyrolysis liquid preparation and its in preparing gynaecology external-use drug |
CN110624062A (en) * | 2019-11-02 | 2019-12-31 | 本冠生物科技(上海)有限公司 | Efficient stable antibacterial powder and preparation method thereof |
CN111053893A (en) * | 2019-12-30 | 2020-04-24 | 重庆宫妙生物科技有限公司 | Antibacterial effervescent tablet and preparation method thereof |
CN112386662A (en) * | 2020-10-23 | 2021-02-23 | 安徽科治医疗科技有限公司 | Gynecological bacteriostatic temperature-sensitive gel and preparation method thereof |
CN112386666A (en) * | 2019-08-19 | 2021-02-23 | 西安泉脉生物科技有限公司 | Traditional Chinese medicine for pudendum care, gel and method |
CN113995793A (en) * | 2021-12-21 | 2022-02-01 | 海而思(郑州)科技有限公司 | Chlorhexidine acetate ointment and preparation method thereof |
CN115317540A (en) * | 2022-08-10 | 2022-11-11 | 广东同德药业有限公司 | Foam bacteriostatic agent |
CN115317527A (en) * | 2022-08-10 | 2022-11-11 | 广东同德药业有限公司 | Plant bacteriostatic agent |
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- 2015-08-20 CN CN201510514713.4A patent/CN106466454A/en active Pending
Cited By (12)
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CN107812137A (en) * | 2017-10-25 | 2018-03-20 | 北京中蜜科技发展有限公司 | A kind of draft skin bacteriostatic gel of propolis-containing and preparation method thereof |
CN107661494A (en) * | 2017-11-20 | 2018-02-06 | 方晓东 | It is a kind of to be used for gynaecological imflammation, the Chinese medicine composition gel of koro and its production technology |
CN108452295A (en) * | 2018-03-28 | 2018-08-28 | 丹东欣时代生物医药科技有限公司 | A kind of compact gel and preparation method antibacterial, that adjust microecological balance |
CN108721544A (en) * | 2018-04-25 | 2018-11-02 | 四川生命源健康管理有限公司 | The externally-applied female of anticancer function is sprayed |
CN108785680A (en) * | 2018-07-10 | 2018-11-13 | 杨先锋 | It is a kind of to be applied using the gel of biomass through pyrolysis liquid preparation and its in preparing gynaecology external-use drug |
CN112386666A (en) * | 2019-08-19 | 2021-02-23 | 西安泉脉生物科技有限公司 | Traditional Chinese medicine for pudendum care, gel and method |
CN110624062A (en) * | 2019-11-02 | 2019-12-31 | 本冠生物科技(上海)有限公司 | Efficient stable antibacterial powder and preparation method thereof |
CN111053893A (en) * | 2019-12-30 | 2020-04-24 | 重庆宫妙生物科技有限公司 | Antibacterial effervescent tablet and preparation method thereof |
CN112386662A (en) * | 2020-10-23 | 2021-02-23 | 安徽科治医疗科技有限公司 | Gynecological bacteriostatic temperature-sensitive gel and preparation method thereof |
CN113995793A (en) * | 2021-12-21 | 2022-02-01 | 海而思(郑州)科技有限公司 | Chlorhexidine acetate ointment and preparation method thereof |
CN115317540A (en) * | 2022-08-10 | 2022-11-11 | 广东同德药业有限公司 | Foam bacteriostatic agent |
CN115317527A (en) * | 2022-08-10 | 2022-11-11 | 广东同德药业有限公司 | Plant bacteriostatic agent |
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Application publication date: 20170301 |