CN108721544A - The externally-applied female of anticancer function is sprayed - Google Patents

The externally-applied female of anticancer function is sprayed Download PDF

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CN108721544A
CN108721544A CN201810377994.7A CN201810377994A CN108721544A CN 108721544 A CN108721544 A CN 108721544A CN 201810377994 A CN201810377994 A CN 201810377994A CN 108721544 A CN108721544 A CN 108721544A
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externally
anticancer function
sprayed
applied female
female
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张俊琴
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Sichuan Life Source Health Management Co Ltd
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Sichuan Life Source Health Management Co Ltd
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

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Abstract

The invention discloses gynaecological applications technical field, specific field is that the externally-applied female of anticancer function is sprayed, and the externally-applied female spraying of the anticancer function is made of following weight ratio, the tuber of stemona 5%~10%, dandelion 10%~15%, Java brucea 4%~9%, active sugar 1%~3%, Poria cocos 8%~12%, collargol 0.8%~2%, 1,2- butanediols 18%~22%, parahydroxyacet-ophenone 8%~12%, chlorhexidine acetate 0.1%~0.5%, caramel 0.1%~1%, remaining is seawater；The externally-applied female spraying that anticancer function is made using Chinese medicine as raw material has many advantages, such as that raw material is easy to get, to be formulated reasonable and bactericidal and bacteriostatic effect good, the various bacterias such as human papilloma virus and herpes simplex virus virus can be effectively killed, there is certain prevention effect to cervical carcinoma.

Description

The externally-applied female of anticancer function is sprayed
Technical field
The present invention relates to gynaecological applications technical field, specific field is that the externally-applied female of anticancer function is sprayed.
Background technology
Cervical carcinoma is to cause the second of female patient death most common, with the increase at age, cervical cancer pathogenesis rate and The death rate increases.Too early (< 16 years old), sexual life is disorderly, active, and sexual life is unclean for first sexual life, more, the mouth of final recognition frequency Contraceptive is taken, is smoked, host genetic neurological susceptibility, nutritional deficiency etc. is all the promoting factor of cervical cancer pathogenesis.However, demonstrate,proving already Bright, Detection of high risk human papillomavirus (HR-HPV), up to 13 kinds of high-risk HPVs including 16,18,31,33,35 etc. continue Infection is the arch-criminal of cervical cancer pathogenesis, and HPV circulation ways, also can be by sharing towel, toilet seat etc. based on spreading through sex intercourse Vertical transmission etc. between propagation and mother and baby indirectly, in view of this ensures the sanitation and hygiene of private parts, secretion is avoided to stimulate, actively antibacterial It is anti-inflammatory to prevent the viral Via vagina such as human papilloma virus and herpes simplex virus from entering in uterine cavity, to effectively reduce uterine neck The incidence probability of cancer.
Invention content
It is mentioned above in the background art to solve the purpose of the present invention is to provide the spraying of the externally-applied female of anticancer function Problem.
To achieve the above object, the present invention provides the following technical solutions：The externally-applied female of anticancer function is sprayed, the anticancer The externally-applied female spraying of effect is composed of the following components：
The tuber of stemona, dandelion, Java brucea, Bacillus acidi lactici/pear juice tunning filtrate, activity is sugared, Poria cocos, collargol, and 1, 2- butanediols, parahydroxyacet-ophenone, chlorhexidine acetate, caramel, remaining is seawater.
Preferably, the externally-applied female spraying of the anticancer function is made of following weight ratio：
The tuber of stemona 5%~10%, dandelion 10%~15%, Java brucea 4%~9%, active sugar 1%~3%, Poria cocos 8%~12%, collargol 0.8%~2%, 1,2- butanediol 18%~22%, parahydroxyacet-ophenone 8%~12%, acetic acid chlorine Oneself fixed 0.1%~0.5%, and caramel 0.1%~1%, remaining is seawater.
Preferably, in the seawater sodium chloride a concentration of 0.8%~1%.
Preferably, the sugared preparation method of activity includes the following steps：
1) use plant high speed disintegrator by dried mushroom dry grinding at the dried mushroom powder that grain size is 100~200 mesh, and by dried mushroom Powder is with alcohol with volume ratio 1~2：1 ratio is mixed to prepare paste dried mushroom powder；
2) by paste dried mushroom powder made from step 1) and distilled water with volume ratio for 1：18~22 ratio mixing, 40~70 Constant temperature impregnates 3~4 hours obtained dried mushroom hot-water soak mixtures in DEG C water bath；
3) dried mushroom hot-water soak mixture made from step 2) is filtered by the way that pump is filtered by vacuum, obtains first-time filtrate And filter residue；
4) filter residue and distilled water obtained step 3) is with volume ratio 1:15~20 ratio mixing, 40~70 DEG C waters Vacuum filtration pump, which filter, after constant temperature impregnates 3~4 hours in bath obtains secondary filtrate and filter residue, merges first-time filtrate and two It is sugared that secondary filtrate obtains activity.
Compared with prior art, the beneficial effects of the invention are as follows：The externally-applied female of anticancer function is sprayed, and the present invention is with Chinese medicine For raw material, have many advantages, such as that raw material is easy to get, is formulated rationally and bactericidal and bacteriostatic effect is good, the tuber of stemona can inhibit pruritus vulvae, and dandelion can be clear Thermal detoxification is a kind of broad spectrum antibiotic, Java brucea can putrefaction-removing granulation-promoting, collargol restraining and sterilizing bacteria, Bacillus acidi lactici/pear juice tunning Filtrate, which can boost metabolism, improves skin elasticity, and especially sugar has preferable anticancer effect to activity, can effectively kill people Class papillomavirus and herpes simplex virus reduce the possibility that women suffers from cervical carcinoma, the externally-applied female spray of this anticancer function Mist can the various bacterias virus such as staphylococcus aureus, Escherichia coli, human papilloma virus and herpes simplex virus effectively processed, And bacteriostasis rate is respectively 94.4%, 95.7%, 91.9% and 92.1%, there is certain prevention effect to cervical carcinoma.
Specific implementation mode
Below in conjunction with the embodiment of the present invention, technical scheme of the present invention is clearly and completely described, it is clear that institute The embodiment of description is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, Every other embodiment obtained by those of ordinary skill in the art without making creative efforts, belongs to this hair The range of bright protection.
Embodiment 1：
The raw material composition and weight ratio of the externally-applied female spraying of this anticancer function are as follows：
The tuber of stemona 5%, dandelion 10%, Java brucea 4%, active sugar 1%, Poria cocos 8%, collargol 0.8%, 1,2- fourths two Alcohol 18%, parahydroxyacet-ophenone 8%, chlorhexidine acetate 0.1%, caramel 0.1%, remaining is seawater.
The externally-applied female spraying of this anticancer function is made by following steps：According to above-mentioned weight ratio by the tuber of stemona, dandelion, Java brucea, it is 1 that volume ratio is added after Poria cocos mixing:In 10 distilled water, heating is decocted and is filtered after sixty minutes, is concentrated the filtrate to After 0.5 times of former mixed volume, Bacillus acidi lactici/pear juice tunning filtrate of above-mentioned weight ratio is added, activity is sugared, colloidal state Silver, 1,2- butanediol, parahydroxyacet-ophenone, chlorhexidine acetate, caramel, seawater can be obtained the externally-applied female spray of anticancer function Mist, the externally-applied female of anticancer function is sprayed to staphylococcus aureus, Escherichia coli, human papilloma in the embodiment 1 Poison and the fungistatic effect of herpes simplex virus are shown in Table 1.
Embodiment 2：
The raw material composition and weight ratio of the externally-applied female spraying of this anticancer function are as follows：
The tuber of stemona 7%, dandelion 12%, Java brucea 6%, active sugar 1%, Poria cocos 9%, collargol 1%, 1,2- butanediols 20%, parahydroxyacet-ophenone 10%, chlorhexidine acetate 0.2%, caramel 0.5%, remaining is seawater.
The externally-applied female spraying of this anticancer function is made by following steps：According to above-mentioned weight ratio by the tuber of stemona, dandelion, Java brucea, it is 1 that volume ratio is added after Poria cocos mixing:In 10 distilled water, heating is decocted and is filtered after sixty minutes, is concentrated the filtrate to After 0.5 times of former mixed volume, Bacillus acidi lactici/pear juice tunning filtrate of above-mentioned weight ratio is added, activity is sugared, colloidal state Silver, 1,2- butanediol, parahydroxyacet-ophenone, chlorhexidine acetate, caramel, seawater can be obtained the externally-applied female spray of anticancer function Mist, the externally-applied female of anticancer function is sprayed to staphylococcus aureus, Escherichia coli, human papilloma in the embodiment 2 Poison and the fungistatic effect of herpes simplex virus are shown in Table 1.
Embodiment 3：
The raw material composition and weight ratio of the externally-applied female spraying of this anticancer function are as follows：
The tuber of stemona 7%, dandelion 12%, Java brucea 6%, active sugar 2%, Poria cocos 9%, collargol 1%, 1,2- butanediols 20%, parahydroxyacet-ophenone 10%, chlorhexidine acetate 0.2%, caramel 0.5%, remaining is seawater.
The externally-applied female spraying of this anticancer function is made by following steps：According to above-mentioned weight ratio by the tuber of stemona, dandelion, Java brucea, it is 1 that volume ratio is added after Poria cocos mixing:In 10 distilled water, heating is decocted and is filtered after sixty minutes, is concentrated the filtrate to After 0.5 times of former mixed volume, Bacillus acidi lactici/pear juice tunning filtrate of above-mentioned weight ratio is added, activity is sugared, colloidal state Silver, 1,2- butanediol, parahydroxyacet-ophenone, chlorhexidine acetate, caramel, seawater can be obtained the externally-applied female spray of anticancer function Mist, the externally-applied female of anticancer function is sprayed to staphylococcus aureus, Escherichia coli, human papilloma in the embodiment 3 Poison and the fungistatic effect of herpes simplex virus are shown in Table 1.
Embodiment 4：
The raw material composition and weight ratio of the externally-applied female spraying of this anticancer function are as follows：
The tuber of stemona 9%, dandelion 14%, Java brucea 7%, active sugar 1%, Poria cocos 10%, collargol 1.5%, 1,2- fourths Glycol 20%, parahydroxyacet-ophenone 10%, chlorhexidine acetate 0.4%, caramel 0.7%, remaining is seawater.
The externally-applied female spraying of this anticancer function is made by following steps：According to above-mentioned weight ratio by the tuber of stemona, dandelion, Java brucea, it is 1 that volume ratio is added after Poria cocos mixing:In 10 distilled water, heating is decocted and is filtered after sixty minutes, is concentrated the filtrate to After 0.5 times of former mixed volume, Bacillus acidi lactici/pear juice tunning filtrate of above-mentioned weight ratio is added, activity is sugared, colloidal state Silver, 1,2- butanediol, parahydroxyacet-ophenone, chlorhexidine acetate, caramel, seawater can be obtained the externally-applied female spray of anticancer function Mist, the externally-applied female of anticancer function is sprayed to staphylococcus aureus, Escherichia coli, human papilloma in the embodiment 4 Poison and the fungistatic effect of herpes simplex virus are shown in Table 1.
Embodiment 5：
The raw material composition and weight ratio of the externally-applied female spraying of this anticancer function are as follows：
The tuber of stemona 10%, dandelion 15%, Java brucea 9%, active sugar 3%, Poria cocos 12%, collargol 2%, 1,2- fourths two Alcohol 22%, parahydroxyacet-ophenone 12%, chlorhexidine acetate 0.5%, caramel 1%, remaining is seawater.
The externally-applied female spraying of this anticancer function is made by following steps：According to above-mentioned weight ratio by the tuber of stemona, dandelion, Java brucea, it is 1 that volume ratio is added after Poria cocos mixing:In 10 distilled water, heating is decocted and is filtered after sixty minutes, is concentrated the filtrate to After 0.5 times of former mixed volume, Bacillus acidi lactici/pear juice tunning filtrate of above-mentioned weight ratio is added, activity is sugared, colloidal state Silver, 1,2- butanediol, parahydroxyacet-ophenone, chlorhexidine acetate, caramel, seawater can be obtained the externally-applied female spray of anticancer function Mist, the externally-applied female of anticancer function is sprayed to staphylococcus aureus, Escherichia coli, human papilloma in the embodiment 5 Poison and the fungistatic effect of herpes simplex virus are shown in Table 1.
The fungistatic effect of the externally-applied female spraying of 1 anticancer function of table
Conclusion：As shown in Table 1, it is sprayed to private parts using the anticancer function external application of the embodiment of the present invention 1~5 spraying, Twice daily treated, it can staphylococcus aureus, Escherichia coli, human papilloma virus and herpes simplex virus effectively processed Etc. various bacterias virus, the fungistatic effect of wherein embodiment 3 is best, to staphylococcus aureus, Escherichia coli, human pailloma The bacteriostasis rate of virus and herpes simplex virus is respectively 94.4%, 95.7%, 91.9% and 92.1%, is had to cervical carcinoma certain Prevent effect.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace And modification, the scope of the present invention is defined by the appended.

Claims (4)

1. the externally-applied female of anticancer function is sprayed, it is characterised in that：The externally-applied female of the anticancer function is sprayed by following components Composition：
The tuber of stemona, dandelion, Java brucea, Bacillus acidi lactici/pear juice tunning filtrate, activity is sugared, Poria cocos, collargol, 1,2- fourth Glycol, parahydroxyacet-ophenone, chlorhexidine acetate, caramel, remaining is seawater.
2. the externally-applied female of anticancer function according to claim 1 is sprayed, which is characterized in that the women of the anticancer function External application spraying is made of following weight ratio：
The tuber of stemona 5%~10%, dandelion 10%~15%, Java brucea 4%~9%, active sugar 1%~3%, Poria cocos 8%~ 12%, collargol 0.8%~2%, 1,2- butanediol 18%~22%, parahydroxyacet-ophenone 8%~12%, chlorhexidine acetate 0.1%~0.5%, caramel 0.1%~1%, remaining is seawater.
3. the externally-applied female of anticancer function according to claim 1 is sprayed, which is characterized in that sodium chloride in the seawater A concentration of 0.8%~1%.
4. the externally-applied female of anticancer function according to claim 1 is sprayed, which is characterized in that the sugared preparation method of activity Include the following steps：
1) use plant high speed disintegrator by dried mushroom dry grinding at the dried mushroom powder that grain size is 100~200 mesh, and by dried mushroom powder With alcohol with volume ratio 1~2：1 ratio is mixed to prepare paste dried mushroom powder；
2) by paste dried mushroom powder made from step 1) and distilled water with volume ratio for 1：18~22 ratio mixing, 40~70 is Celsius It spends constant temperature in water-bath and impregnates 3~4 hours obtained dried mushroom hot-water soak mixtures；
3) dried mushroom hot-water soak mixture made from step 2) is filtered by the way that pump is filtered by vacuum, obtains first-time filtrate and filter Slag；
4) filter residue and distilled water obtained step 3) is with volume ratio 1:15~20 ratio mixing, 40~70 DEG C water baths Vacuum filtration pump, which filter, after interior constant temperature impregnates 3~4 hours obtains secondary filtrate and filter residue, merges first-time filtrate and secondary filter It is sugared that liquid obtains activity.
CN201810377994.7A 2018-04-25 2018-04-25 The externally-applied female of anticancer function is sprayed Pending CN108721544A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111000955A (en) * 2019-12-30 2020-04-14 重庆宫妙生物科技有限公司 Firming antibacterial gel and preparation method thereof
CN111000954A (en) * 2019-12-30 2020-04-14 重庆宫妙生物科技有限公司 Antibacterial gel and preparation method thereof
CN111728987A (en) * 2020-07-09 2020-10-02 广西妙韵圆生药业有限公司 Traditional Chinese medicine penetrating fluid for treating cervical HPV virus infection

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CN1265320A (en) * 2000-01-13 2000-09-06 余徽 Natural herbal medicine composition with the functions of stopping itching, disinfection and antiphlogosis and its preparation
CN102160887A (en) * 2010-11-19 2011-08-24 厦门金日制药有限公司 Medicament for treating gynecological inflammation and preparation method thereof
CN104814918A (en) * 2015-05-13 2015-08-05 朱敏 Moisturizing facial mask solution, preparation method of moisturizing facial mask solution and moisturizing facial mask
CN106466454A (en) * 2015-08-20 2017-03-01 康多宝医疗健康产品（湖南）有限公司 A kind of prevention and the gel for the treatment of gynecological inflammation

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Publication number Priority date Publication date Assignee Title
CN1120442A (en) * 1994-03-22 1996-04-17 丹东市中药饮片厂 Pudenda lotion and its prepn. method
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