CN102462768A - External care solution for women - Google Patents
External care solution for women Download PDFInfo
- Publication number
- CN102462768A CN102462768A CN2010105372464A CN201010537246A CN102462768A CN 102462768 A CN102462768 A CN 102462768A CN 2010105372464 A CN2010105372464 A CN 2010105372464A CN 201010537246 A CN201010537246 A CN 201010537246A CN 102462768 A CN102462768 A CN 102462768A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- care solution
- liquid
- supercritical extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims abstract description 22
- 239000007788 liquid Substances 0.000 claims abstract description 22
- 238000000194 supercritical-fluid extraction Methods 0.000 claims abstract description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 7
- 239000009806 pulsatillae Substances 0.000 claims description 5
- 241000717679 Mosla Species 0.000 claims description 4
- 238000005538 encapsulation Methods 0.000 claims description 4
- 239000000284 extract Substances 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 238000010298 pulverizing process Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 11
- 230000002147 killing effect Effects 0.000 abstract description 7
- 208000003251 Pruritus Diseases 0.000 abstract description 6
- 206010061218 Inflammation Diseases 0.000 abstract description 5
- 238000004140 cleaning Methods 0.000 abstract description 5
- 230000004054 inflammatory process Effects 0.000 abstract description 4
- 230000002401 inhibitory effect Effects 0.000 abstract description 4
- 241000206469 Pulsatilla Species 0.000 abstract description 3
- 230000007803 itching Effects 0.000 abstract description 3
- 241000238631 Hexapoda Species 0.000 abstract description 2
- 238000002360 preparation method Methods 0.000 abstract description 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 235000002566 Capsicum Nutrition 0.000 abstract 1
- 239000006002 Pepper Substances 0.000 abstract 1
- 235000016761 Piper aduncum Nutrition 0.000 abstract 1
- 235000017804 Piper guineense Nutrition 0.000 abstract 1
- 244000203593 Piper nigrum Species 0.000 abstract 1
- 235000008184 Piper nigrum Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000000474 nursing effect Effects 0.000 abstract 1
- 230000003750 conditioning effect Effects 0.000 description 9
- 230000003110 anti-inflammatory effect Effects 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 210000004392 genitalia Anatomy 0.000 description 4
- 241000222122 Candida albicans Species 0.000 description 3
- 206010046914 Vaginal infection Diseases 0.000 description 3
- 229940095731 candida albicans Drugs 0.000 description 3
- 244000045947 parasite Species 0.000 description 3
- 206010002198 Anaphylactic reaction Diseases 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 208000007074 Trichomonas Vaginitis Diseases 0.000 description 2
- 208000025206 Trichomonas vaginitis urogenital infection Diseases 0.000 description 2
- 208000003455 anaphylaxis Diseases 0.000 description 2
- 230000001139 anti-pruritic effect Effects 0.000 description 2
- 239000003908 antipruritic agent Substances 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 208000008710 Amebic Dysentery Diseases 0.000 description 1
- 206010001986 Amoebic dysentery Diseases 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 208000004145 Endometritis Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 208000006374 Uterine Cervicitis Diseases 0.000 description 1
- 201000008100 Vaginitis Diseases 0.000 description 1
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 206010008323 cervicitis Diseases 0.000 description 1
- 210000003756 cervix mucus Anatomy 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000000749 insecticidal effect Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 230000035943 smell Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a female external care solution and a preparation method thereof. The nursing liquid is prepared from the following Chinese medicinal materials (by weight portion) through CO2Extracting the liquid medicine by supercritical extraction. 2-6 parts of fructus cnidii, 2-6 parts of herba elsholtziae, 1-5 parts of pepper and 1-3 parts of Chinese pulsatilla root. The pH value of the care solution is 6-7, and the care solution has remarkable effects of inhibiting bacteria, killing insects, resisting inflammation, relieving itching, cleaning pudendum and removing peculiar smell.
Description
Technical field
The present invention relates to feminine care products, be specifically related to externally-applied female conditioning liquid and preparation method thereof.
Background technology
Gynecological's pudendum, colpitis are a kind of commonly encountered diseases, frequently-occurring disease.Investigation shows, adult female's infection in various degree in the whole world about 87% gynecological inflammation, clinical common gynecologic inflammation has vaginitis, cervicitis, endometritis etc.Symptom such as gynecological inflammation mainly shows as pudendal pruritus, scorching hotly swells and ache clinically, leucorrhoea grow in quantity, frequent micturition, urgent micturition, dysurea, abnormal smells from the patient are unusual; Outbreak repeatedly; Prolongedly do not heal, have influence on routine work and with people's contacts, bring serious physiology and psychological burden to the patient.At present feminine care liquid or with antibacterial be main, or be main with the cleaning external genital, act on comparatively single.
Summary of the invention
The technical problem that the present invention will solve provides a kind of externally-applied female conditioning liquid; Can not only effectively suppress Candida albicans, staphylococcus aureus; And have the trichomonas vaginitis of killing, antiinflammatory, itching relieving and significantly act on; And reach the effect of cleaning external genital, thereby reach the purpose of treating both the principal and secondary aspects of a disease through reducing secretions.Another technical problem that the present invention will solve provides the method for preparing of externally-applied female conditioning liquid.
The present invention realizes through following technical scheme:
This feminine care liquid is characterized in that: by following weight portion Chinese medicine, through CO
2Make behind its medicinal liquid of supercritical extraction:
2～6 parts of Fructus Cnidiis, 2～6 parts of Herba Moslaes, 1～5 part in Pericarpium Zanthoxyli, 1～3 part of the Radix Pulsatillae.
The method for preparing of this feminine care liquid is characterized in that comprising the following steps:
(1) gets Fructus Cnidii, Pericarpium Zanthoxyli, Herba Moslae, the Radix Pulsatillae, mix by the described weight proportion of claim 1 and pulverize, add 1～3 times of ethanol of above-mentioned Chinese medicine weight, under the control temperature is 35 ℃～55 ℃, the condition of pressure 30Mpa～40Mpa, carry out CO
2Supercritical extraction 2 hours～4 hours obtains Chinese medicine extraction medicinal liquid;
(2) get the Chinese medicine extract that step (1) obtains, add mix homogeneously in 1000 times the water, divide again to be filled in the medicine bottle, and make encapsulation process.
Advantage of the present invention:
One, has broad-spectrum antibacterial, antiinflammatory and itching-relieving action
This conditioning liquid all has bacteriostasis to Candida albicans, staphylococcus aureus, escherichia coli and Pseudomonas aeruginosa, especially Candida albicans is had strong inhibitory action, and minimal inhibitory concentration is 2mg/ml.This conditioning liquid antiinflammatory action is remarkable, and antipruritic suppression ratio reaches 68%.
Two, have and significantly kill the trichomonas vaginitis effect
Use this conditioning liquid after 24 hours mirror observe down infusorian mortality rate in the vaginal secretions BIAO and BEN, will not move, the edge is not put in order, include a large amount of particulate circular polypides is judged to be dead infusorian, the infusorian killing rate can reach more than 80%.
Three, safe in utilization
This conditioning liquid has no stimulation to vaginal mucosa, local skin anaphylaxis or systemic anaphylaxis also do not occur, and is safe in utilization.
The major function of each medicine among the present invention:
One, Fructus Cnidii: the effect of tool warming the kidney to invigorate YANG, expelling wind and cold, parasite killing pain relieving, clinical its dampness wind dispelling insecticide effect of getting is used to treat gynecological and all diseases of skin outward.
Two, Pericarpium Zanthoxyli: medication is with a long history, and its pain relieving insecticidal action is used widely in clinical after the Qing Dynasty.Pericarpium Zanthoxyli has inhibitory action in various degree to antibacterial, fungus, has to kill the infusorian effect significantly.
Three, Herba Moslae: expelling insect and relieving itching has significant broad-spectrum antiseptic and pharmacological actions such as antiinflammatory, enhance immunity, and can effectively eliminate stink.
Four, the Radix Pulsatillae: having the effect of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, removing dampness and killing parasites, clinically be usually used in treating bacillary dysentery, amebic dysentery and gynecology colpitis etc., is early to find to have one of Chinese medicine of obviously killing the trichomonal vaginitis effect.
To sum up, this conditioning liquid has broad-spectrum antibacterial, parasite killing, inflammation-resisting itch-stopping and the effect of cleaning external genital, thereby reaches the multi-functional effect of treating both the principal and secondary aspects of a disease, and side effect such as non-stimulated, allergy.
The specific embodiment
Embodiment one:
(1) get 2 parts of Fructus Cnidiis, 3 parts of Herba Moslaes, 4 parts in Pericarpium Zanthoxyli, 2 parts of the Radix Pulsatillaes mix to be pulverized, and add 2 times of ethanol of above-mentioned Chinese medicine weight, under the control temperature is 45 ℃, the condition of pressure 40Mpa, carry out CO
2Supercritical extraction 2 hours obtains Chinese medicine extraction medicinal liquid;
(2) get the Chinese medicine extract that step (1) obtains, add mix homogeneously in 1000 times the water, divide again to be filled in the medicine bottle, and make encapsulation process.
Be mainly used in and kill infusorian and antipruritic.
Embodiment two:
(1) get 3 parts of Fructus Cnidiis, 6 parts of Herba Moslaes, 1 part in Pericarpium Zanthoxyli, 2 parts of the Radix Pulsatillaes mix to be pulverized, and add 1 times of ethanol of above-mentioned Chinese medicine weight, under the control temperature is 35 ℃, the condition of pressure 40Mpa, carry out CO
2Supercritical extraction 2 hours obtains Chinese medicine extraction medicinal liquid;
(2) get the Chinese medicine extract that step (1) obtains, add mix homogeneously in 1000 times the water, divide again to be filled in the medicine bottle, and make encapsulation process.
Be mainly used in antiinflammatory and cleaning external genital.
Claims (2)
1. a feminine care liquid is characterized in that: by following weight portion Chinese medicine, through CO
2Make behind its medicinal liquid of supercritical extraction: 2～6 parts of Fructus Cnidiis, 2～6 parts of Herba Moslaes, 1～5 part in Pericarpium Zanthoxyli, 1～3 part of the Radix Pulsatillae.
2. the method for preparing of a feminine care liquid is characterized in that comprising the following steps:
(1) gets Fructus Cnidii, Pericarpium Zanthoxyli, Herba Moslae, the Radix Pulsatillae; Mix pulverizing by the described weight proportion of claim 1; 1～3 times of ethanol that adds above-mentioned Chinese medicine weight; Under the control temperature is 35 ℃～55 ℃, the condition of pressure 30Mpa～40Mpa, carried out the CO2 supercritical extraction 2 hours～4 hours, obtain Chinese medicine extraction medicinal liquid;
(2) get the Chinese medicine extract that step (1) obtains, add mix homogeneously in 1000 times the water, divide again to be filled in the medicine bottle, and make encapsulation process.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105372464A CN102462768A (en) | 2010-11-09 | 2010-11-09 | External care solution for women |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105372464A CN102462768A (en) | 2010-11-09 | 2010-11-09 | External care solution for women |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102462768A true CN102462768A (en) | 2012-05-23 |
Family
ID=46067076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105372464A Pending CN102462768A (en) | 2010-11-09 | 2010-11-09 | External care solution for women |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102462768A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306513A (en) * | 2014-11-01 | 2015-01-28 | 李钦源 | Production technology of female external care solution |
| CN113318179A (en) * | 2021-06-30 | 2021-08-31 | 李占芳 | Kelp polysaccharide tightening antibacterial liquid and preparation method thereof |
| CN113559147A (en) * | 2021-08-19 | 2021-10-29 | 武汉禾本泰医药科技有限公司 | A pharmaceutical composition for treating gynecological inflammation, and its preparation method |
-
2010
- 2010-11-09 CN CN2010105372464A patent/CN102462768A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104306513A (en) * | 2014-11-01 | 2015-01-28 | 李钦源 | Production technology of female external care solution |
| CN113318179A (en) * | 2021-06-30 | 2021-08-31 | 李占芳 | Kelp polysaccharide tightening antibacterial liquid and preparation method thereof |
| CN113559147A (en) * | 2021-08-19 | 2021-10-29 | 武汉禾本泰医药科技有限公司 | A pharmaceutical composition for treating gynecological inflammation, and its preparation method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106334067B (en) | Gynecological gel containing silver ion antibacterial agent, preparation method and application | |
| CN101347541B (en) | Medicament for treating gynecology disease and dermatopathy and preparation thereof | |
| CN103385926B (en) | Antibiosis gel for curing cervical and vaginal diseases of gynaecology | |
| CN103110868A (en) | Skin care solution and preparation method thereof | |
| CN105833333A (en) | Nursing pad with antibacterial, itching relieving and disinfection functions and method for manufacturing nursing pad | |
| US10478463B2 (en) | External-use medicament for cleaning and care of the ovaries, vagina, and vulva | |
| CN102205077B (en) | Gynecopathy external use washing lotion and preparation method thereof | |
| CN102755578B (en) | Washing liquid for treating gynecologic diseases and preparation method thereof | |
| CN104771671B (en) | A kind of traditional Chinese medicine lotion for treating gynaecological imflammation | |
| CN102462768A (en) | External care solution for women | |
| CN101288754B (en) | Huyuebao preparation | |
| CN102988844A (en) | Gynaecological gel and extraction method thereof | |
| CN104288552A (en) | Vagina-cleaning care solution and preparation method thereof | |
| CN104587033B (en) | A kind of Nano Silver rhinitis ointment | |
| CN103751532A (en) | Traditional Chinese medicine composition for treating gynecological inflammation and preparation method thereof | |
| CN103239676A (en) | Topical pharmaceutical composition for preventing and treating bacterial vaginosis | |
| CN103372087A (en) | Skin protecting health-care traditional Chinese medicine composition | |
| CN103721138B (en) | A kind of traditional Chinese medicine for external application and its preparation method treating rosacea | |
| CN105535723A (en) | Traditional Chinese medicinal composition for treating vulvitis and external preparation of traditional Chinese medicinal composition | |
| CN103341044B (en) | Itching-relieving compound preparation and preparation method thereof | |
| CN102462767A (en) | Vaginal effervescent tablet and preparation method thereof | |
| CN104922449A (en) | Traditional Chinese medicine disinfection solution and preparation method thereof | |
| CN105311328A (en) | Traditional Chinese medicine composition for treating gynecological inflammation and application thereof | |
| CN1431012A (en) | Externally used Chinese herbal medicine for treating gynecology inflammation | |
| CN103599272B (en) | Chinese herbal lotion for the treatment of gynecological inflammation and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120523 |