CN103070963A - Traditional Chinese medicine preparation for treating candida albicans infection diseases - Google Patents

Traditional Chinese medicine preparation for treating candida albicans infection diseases Download PDF

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CN103070963A
CN103070963A CN2013100583918A CN201310058391A CN103070963A CN 103070963 A CN103070963 A CN 103070963A CN 2013100583918 A CN2013100583918 A CN 2013100583918A CN 201310058391 A CN201310058391 A CN 201310058391A CN 103070963 A CN103070963 A CN 103070963A
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chinese medicine
candida albicans
medicine preparation
weight portions
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CN103070963B (en
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梁贵文
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating candida albicans infection diseases. The traditional Chinese medicine preparation comprises the following ingredients in parts by weights: 6 to 10 parts of golden cypress, 6 to 10 parts of coptis chinensis, 6 to 10 parts of skullcap, 3 to 8 parts of cortex pseudolaricis, 3 to 8 parts of cortex dictamni, 3 to 8 parts of hibiscus syriacus, 3 to 8 parts of gallnut, 3 to 6 parts of fructus kochiae and 3 to 6 parts of fructus cnidii. The recipe of the traditional Chinese medicine preparation has the advantages that the cure rate on the chronic candida albicans infection diseases is high, the effect taking speed is high, the disease cannot easily recur after the cure, the patients have no pain, the treatment cost is low, and in addition, no toxic or side effect is caused on the body.

Description

A kind of Chinese medicine preparation that infects the Candida albicans disease for the treatment of
Technical field
The technical field of Chinese crude drug under the present invention, specifically a kind of Chinese medicine formula that infects the Candida albicans disease for the treatment of.
Background technology
Candida albicans is a kind of fungus, often invades skin mucosa, often betides men and women's genitals, internal organs and whole body.Genitals is candidiasis balanitis, candidal vaginitis (also claiming colpitis mycotica) because infecting the common disease of candidiasis.The behavior of disease trafficability characteristic is propagated mutually, and is obstinate difficult, repeatedly outbreak.The disease that the male infects involves body of penis, scrotum, femoribus internus and groin etc. to be located, and such as untimely systematic treating, outbreak can cause the glans penis atrophy repeatedly, is developed to drying property occlusive balanitis, concurrent glans penis cancer when serious.The candidiasis balanitis also can cause Other diseases, such as phallic inflammation such as prostatitis, orchitis, epididymitis, deferentitiies, also easily cause the up inflammation of urinary system, be more common in cystitis, nephritis, pyelonephritis etc., deal with improperly such as acute onset and can cause uremia's threat to life.The women infects Candida albicans can cause vaginitis, also can cause cervicitis, cervical erosion, salpingitis, oophoritis, pelvic inflammatory disease etc., can cause infertile when serious.At present, approximately 1,600,000 people of patient that Candida albicans causes epidemic disease suffer from China, candidiasis balanitis patient 600,000 people wherein, and the vaginitis patient is 1,000,000 people approximately, the person between twenty and fifty that patient 80% enlivens for property.
The disease of present western medical treatment candida albicans infection, overall therapeutic effect is not good, 50% above patient's obstinate, outbreak is controlled heavier and heavier repeatedly.Its main cause is for the Western medicine of Candida albicans or externally applied ointment the effect that suppresses Candida albicans only to be arranged, but does not kill function, and at once recurrence appears in inducement.The patient that onset infects Candida albicans only is Mucocutaneous diseases, oral medicine and intravenous drip poor effect, and expensive, especially the medicine for external use that contains hormones, can cause after the medication repeatedly showing effect, increased again the difficulty of follow-up regular treatment, and hormone also can cause harmful effect to other organ of health.
Summary of the invention
Infect not good, the easy recurrence of Candida albicans disease effects, expensive for solving existing Drug therapy, and the hormone that contains in the medicine can cause dysgenic problem to other organ of health, the invention discloses a kind of Chinese medicine preparation that infects the Candida albicans disease for the treatment of, purpose be the treatment candida albicans infection the persistent ailment treatment more height, instant effect, more after difficult recurrence, patient's no pain, medical expense low,
And health is had no side effect.
Realize that the above-mentioned purpose technical scheme is, the Chinese medicine preparation that the Candida albicans disease is infected in treatment comprises that parts by weight are 6~10 parts Cortex Phellodendri, Rhizoma Coptidis, Radix Scutellariae, parts by weight are 3~8 parts Cortex Pseudolaricis, Cortex Dictamni, Cortex Hibisci, Galla Chinensis, and parts by weight are 3~6 parts the Fructus Kochiae and Fructus Cnidii.
Also addible Chinese medicinal ingredients has 3~8 parts of Radixs Stemonae, 2~5 parts of Rhizoma Smilacis Glabraes, 2~5 portions of Flos Loniceraes, 3~8 parts of Flos Chrysanthemi Indicis, 2~5 parts of Herba Senecionis Scandentiss, 1~4 part of Alumen in above-mentioned preparation, above composition can add separately in the Chinese medicine formula, also can several mixing add in the Chinese medicine formula, described umber is parts by weight.
When treatment candida albicans infection disease, as long as utilize prescription of the present invention, can be made into any dosage form that now has on the market, the patient that onset infects, the state of an illness is lighter can make this Chinese medicine formula Chinese medicinal decoction, Chinese medicine pill or capsule oral and take, state of an illness moderate is to serious, can be with spraying or the washing liquid of this Chinese medicine formula, therapeutic effect is not processed the restriction of dosage form.
The drug action of each component of Chinese medicine formula of the present invention:
Cortex Phellodendri: resisting pathogenic microbes effect: in vitro tests proves, the Cortex Phellodendri decoct, the water logging agent has bacteriostasis to the various skin fungus, its antibacterial action principle be because of its strong inhibition bacterial respiratory and RNA(ribonucleic acid) synthetic.
The property of medicine: bitter in the mouth, be slightly cold, have no side effect.
Effect: heat clearing and damp drying, eliminating fire and detoxication, distant skin ulcer cure mainly cellulitis sore, eczema pruritus.
Rhizoma Coptidis: resisting pathogenic microbes effect: Huanglian Decoction, water logging agent have inhibitory action to sufficient sole of the foot hair moss bacterium, Candida albicans, and its antibacterial mechanisms is by acting on fungal cell membrane, changing its selectivity, permeability.
The property of medicine: bitter in the mouth, cold in nature, have no side effect.
Effect: clearing away heat-fire, dampness, detoxifcation cure mainly pathopyretic ulcer, vitro inhibition trichomonas vaginitis and eczema.
Fructus Cnidii: the property of medicine: acrid in the mouth, hardship, warm in nature.
Effect: dampness is dispeled the wind, killing parasites for relieving itching.External cures mainly scrotum pruritus due to damp pathogen, eczema scabies moss, married woman resistance itch swell and ache, trichomonal vaginitis.
Cortex Pseudolaricis: resisting pathogenic microbes: multiple pathomycete is had bacteriostasis.
Effect: expelling wind and removing dampness, killing parasites for relieving itching cures mainly scabies moss, eczema, neurodermatitis.
Radix Scutellariae: the property of medicine: bitter in the mouth, cold in nature, have no side effect.
Function cures mainly: heat clearing and damp drying, pathogenic fire reducing detoxifcation.
Radix Scutellariae is proved for the inhibitory action of Candida albicans, " the different extracts of Radix Scutellariae to the In Vitro Bacteriostasis effect of two kinds of deep fungals relatively " of delivering such as pathogenic microorganism teaching and research room of Gannan Medical College, Radix Scutellariae ethanol extraction and decocting liquid all have good antibacterial action to Candida albicans, such as Radix Scutellariae ethanol extract antibacterial circle diameter 28mm, minimal inhibitory concentration MIC12.5~62,5mg/ml; Radix Scutellariae decocting liquid is to Candida albicans antibacterial circle diameter 34mm, minimal inhibitory concentration MIC7.8~15.6mg/ml.Have again Anhui Chinese Medicine College, the clinical institute of Chinese and western medicine also in " the Radix Scutellariae glycosides is on Candida albicans germ tube and adhering impact " article explanation Radix Scutellariae glycosides to the Candida albicans Germination, be stained with inhibitory action with host cell.
The Radix Stemonae: the effect of resisting pathogenic microbes: Radix Stemonae infusion has certain inhibitory action external to some fungus, and Radix Stemonae extract (infusion) can be killed pubic louse, body louse, head louse, and non-stimulated to skin, not only louse is also had stronger killing action to ovum.
The property of medicine: bitter in the mouth, little sweet, slightly warm in nature.
Effect: parasite killing delousing.External cures mainly pubic louse, body louse, pudendal pruritus, scabies moss.
Alumen: be called again Alumen, resisting pathogenic microbes effect: to Candida albicans
Trichomonas vaginitis all has inhibitory action.
The property of medicine: puckery, acid cold.
Effect: external detoxifcation parasite killing, dampness removing to stop itchin.Cure mainly pruritus due to damp pathogen, scabies moss, leukorrhagia pudendal pruritus, malignant boil.
The Fructus Kochiae: the property of medicine: cold in nature, bitter in the mouth, suffering, have no side effect.
Effect: Candida albicans is had inhibitory action, clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.Be used for pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus, sore, scabies moss, pudendum pruritus due to damp pathogen.
Cortex Dictamni: resisting pathogenic microbes effect: the Cortex Dictamni water decoction has inhibitory action to various pathomycetes.
The property of medicine: bitter in the mouth, little suffering, cold in nature.
Function cures mainly: dispeiling pathogenic wind and removing dampness, heat-clearing and toxic substances removing.Cure mainly skin pruritus, rubella, sore, eczema, scabies moss, especially be usually used in that the skin rash is itched, the female genital pruritus due to damp pathogen.
Herba Senecionis Scandentis: resisting pathogenic microbes effect: the Herba Senecionis Scandentis water decoction has broad-spectrum antibacterial action.
The property of medicine: bitter in the mouth, suffering, cold in nature.
Function cures mainly: heat-clearing and toxic substances removing, killing parasites for relieving itching.Cure mainly that pain is swollen, sore, eczema, scabies moss, pudendal pruritus.
Cortex Hibisci: claim again Shrubalthea Bark, the property of medicine: sweet in the mouth, hardship, cold nature, have no side effect.
Effect: clearing away heat-damp and promoting diuresis, killing parasites for relieving itching.Cure mainly pudendal pruritus, scabies moss, eczema scrotum is controlled in external.
Galla Chinensis: the property of medicine: sour in the mouth, puckery.
Effect: can control scrotum eczema, year for a long time cloudy stupid evil moss, foot moss, cervical erosion, mycotic stomatitis.
Rhizoma Smilacis Glabrae: the property of medicine: sweet in the mouth, light, property are flat.
Effect: detoxicating and resolving stagnation of pathogens, expelling wind and removing dampness, cure mainly syphilis, eczema scabies moss.
Flos Chrysanthemi Indici: the property of medicine: bitter in the mouth, suffering, cool in nature.
Effect: heat-clearing and toxic substances removing, cure mainly furuncle, erysipelas, eczema scabies moss.
Flos Lonicerae: resisting pathogenic microbes effect: Flos Lonicerae water logging agent has in various degree inhibitory action external to dermatophytes.
The property of medicine: sweet in the mouth, little hardship, cold in nature.
Effect: heat-clearing and toxic substances removing, cure mainly the carbuncle furuncle.
The beneficial effect of Chinese medicine formula of the present invention is: most of compositions such as Cortex Phellodendri, Rhizoma Coptidis, Cortex Pseudolaricis, Radix Scutellariae, Alumen, Cortex Dictamni, Herba Senecionis Scandentis, Galla Chinensis all have fully elimination and inhibitory action to Candida albicans in the prescription, effect is not subjected to the restriction of any dosage form, cost is low, the cure rate for the treatment of various infection Candida albicans diseases is high, nothing recurrence after curing, treating initial infection and general state of an illness person's medication can be fully recovered in 15~20 days, and severe patient can be fully recovered in 30~70 days, and the healing relapse rate is extremely low.
The specific embodiment
Below in conjunction with embodiment summary of the invention is done specific description.
Embodiment one: the Chinese medicine formula that the Candida albicans disease is infected in treatment comprises:
Cortex Phellodendri 6 weight portions
Rhizoma Coptidis 7 weight portions
Radix Scutellariae 6 weight portions
Flos Lonicerae 2 weight portions
Cortex Dictamni 5 weight portions
Cortex Hibisci 6 weight portions
Galla Chinensis 5 weight portions
The Fructus Kochiae 3 weight portions
Fructus Cnidii 5 weight portions
The Radix Stemonae 3 weight portions
Rhizoma Smilacis Glabrae 2 weight portions
Above-mentioned prescription is made the method for Chinese medicine decoction: the Chinese medicinal components of above-mentioned parts by weight is soaked 30min, the amount that adds entry is the amount of 6 times of total medical materials, after the immersion, put and decoct with water in the multi-function extractor twice, decoct for the first time 1h, decoct for the second time the water that adds up medical material 5 back of the body amounts, decoct 40min, get twice decocting liquid merging and staticly settle together 12h, filter, boil, in the heat-sealing bag, 105 ℃ of high temperature sterilize packings get final product, and every bag specification is 250ml, just morbidity, when state of an illness the lighter takes, every bag with early, twice of evening or morning, in, evening three times, 10-20 days is a course for the treatment of.
Embodiment two: the Chinese medicine formula that the Candida albicans disease is infected in treatment comprises:
Cortex Phellodendri 10 weight portions
Rhizoma Coptidis 6 weight portions
Radix Scutellariae 10 weight portions
Cortex Pseudolaricis 3 weight portions
Rhizoma Smilacis Glabrae 5 weight portions
Cortex Dictamni 3 weight portions
Cortex Hibisci 3 weight portions
Galla Chinensis 8 weight portions
The Fructus Kochiae 5 weight portions
Fructus Cnidii 3 weight portions
The Radix Stemonae 5 weight portions
Flos Lonicerae 4 weight portions
Flos Chrysanthemi Indici 3 weight portions
Herba Senecionis Scandentis 2 weight portions
Alumen 1 weight portion
Above-mentioned prescription is made the usage of external fumigation and washing agent or spraying: the Chinese medicinal components heating water of above-mentioned parts by weight is soaked 30min, the amount that adds entry is the amount of 6 times of total medical materials, after the immersion, to first stifling again immersion or spraying of affected part, directly act on skin, and the absorbing transmission from skin efficacy of a drug enters blood, reach the purpose of healing, the heavier patient of the state of an illness can use the method, can fully recover in 15~70 days.
Embodiment three: the Chinese medicine formula that the Candida albicans disease is infected in treatment comprises:
Cortex Phellodendri 8 weight portions
Rhizoma Coptidis 10 weight portions
Radix Scutellariae 8 weight portions
Rhizoma Smilacis Glabrae 3 weight portions
Cortex Dictamni 8 weight portions
Cortex Hibisci 8 weight portions
Galla Chinensis 3 weight portions
The Fructus Kochiae 6 weight portions
Fructus Cnidii 6 weight portions
The Radix Stemonae 8 weight portions
Flos Lonicerae 5 weight portions
Flos Chrysanthemi Indici 8 weight portions
Herba Senecionis Scandentis 5 weight portions
Alumen 4 weight portions
Above-mentioned prescription is made medicine pill, first the composition except Alumen being added water boils, when waiting to boil sticky shape, medicinal residues are filtered, its solution is cooled to room temperature naturally, put into again Cera Flava and Alumen, solution is transferred to the low place of temperature,, in the cold compartment of refrigerator of 0 ° of C~4 ° C, stir and after cooling, naturally condense agglomeratingly such as temperature, be shaped into by hand again the ball shape.
When taking Chinese medicine of the present invention, this ball shape preparation can be divided into some pillers and take, every ball is 1g heavily approximately, each serving with 5~7 balls, takes three times in 1st, is all one after each meal, and the pill that utilizes the amount of above-mentioned each component to make can be taken 7 days.
When taking Chinese medicine of the present invention, do not avoid food.
Embodiment four: the Chinese medicine formula that the Candida albicans disease is infected in treatment comprises:
Cortex Phellodendri 7 weight portions
Rhizoma Coptidis 8 weight portions
Radix Scutellariae 9 weight portions
Rhizoma Smilacis Glabrae 4 weight portions
Cortex Dictamni 6 weight portions
Cortex Pseudolaricis 8 weight portions
Cortex Hibisci 4 weight portions
Galla Chinensis 7 weight portions
The Fructus Kochiae 4 weight portions
Fructus Cnidii 4 weight portions
The Radix Stemonae 4 weight portions
Flos Lonicerae 3 weight portions
Flos Chrysanthemi Indici 5 weight portions
Herba Senecionis Scandentis 3 weight portions
Alumen 2 weight portions
Above-mentioned prescription can be utilized prior art to make capsule, spray and all can use, the change of dosage form can not affect its effect.
The therapeutic effect of this Chinese medicine formula is described below in conjunction with concrete case
<1 〉. Li Yongqiang, sex man, 32 years old, the state of an illness: pruritus of balanus, erythema, pimple, adularescent transudate occur, use the external of this Chinese medicine formula, every day fumigation and wash method 30min, week recovery from illness.
<2〉Yang Yecai, the sex man, at 45 years old age, the initial state of an illness: patient diagnosis had used daktarin external, oral fluconazol sheet for infecting the candidiasis balanitis, belong to secondary recurrence situation, use Chinese medicine formula external of the present invention, every day, fumigation and wash method 30min fully recovered in 20 days afterwards, after respectively consolidated 10 days in two seasons of spring and fall of Second Year again, through paying a return visit recurrence.
<3〉Liu Sili, sex man, at 19 years old age, the initial state of an illness: reddened and swollen glans penis, show speckle, foreskin is red and swollen, the shallow table of glans penis is rotten to the corn, pruritus is unbearably and with burn feeling, uses the external fumigation and washing of Chinese medicine formula of the present invention, fumigation in treating healing in 20 days.
<4〉Jiang, the sex man, at 25 years old age, initial disease: this patient is fallen flat in the public bathhouse, infects balanitis, belongs to the onset disease, takes the decoction of Chinese medicine formula of the present invention, every day early, evening twice, be the 250ml medicinal liquid altogether, afterwards healing in 10 days there is no recurrence.
<5〉Xu Jianhua, the sex woman, at 34 years old age, initial disease: pruritus vulvae is unbearably, vaginal mucosa is rubescent, edema, pudendum flushing, swelling, vesicle shape pimple is arranged, involved around the pudendum and external Chinese medicine formula fumigation and wash method of the present invention erythema appears, in femoribus internus, in conjunction with taking pill of the present invention, every day fumigation and wash method 30min, early, take pill twice, afterwards recovery from illness in 18 days evening.
<6〉Zhang Ping, sex man, 55 years old age, initial disease: glans penis, foreskin redness, the adularescent sepage has been involved femoribus internus, scrotum, mons pubes, pruritus unbearably, burning sensation is arranged, constantly recurrence is used Chinese medicine formula external fumigation and washing of the present invention, again in conjunction with Chinese medicine decoction over ill 8 years, every day fumigation and wash method 30min, take decoction, common 250ml medicinal liquid, afterwards recovery from illness in 70 days early.
<7〉Xu certain, sex woman, 39 years old age, initial disease: genital skin flushing, vaginal mucosa are congested, pruritus unbearably, uses Chinese medicine formula external of the present invention, fumigation in treating was fully recovered in 20 days afterwards.
Below only for to further specify the cited specific embodiment of content of the present invention, the replacement of all identical effect Chinese medicinal ingredients or the change of dosage form all should drop within the scope of the invention.

Claims (4)

1. treat the Chinese medicine preparation that infects the Candida albicans disease for one kind, it is characterized in that, this Chinese medicine preparation comprises that parts by weight are 6~10 parts Cortex Phellodendri, Rhizoma Coptidis, Radix Scutellariae, parts by weight are 3~8 parts Cortex Pseudolaricis, Cortex Dictamni, Cortex Hibisci, Galla Chinensis, and parts by weight are 3~6 parts the Fructus Kochiae and Fructus Cnidii.
2. the Chinese medicine preparation of Candida albicans disease is infected in treatment according to claim 1, it is characterized in that, this Chinese medicine preparation comprises that also parts by weight are 3~8 parts the Radix Stemonae, in the Flos Chrysanthemi Indici one or both.
3. the Chinese medicine preparation of Candida albicans disease is infected in treatment according to claim 1, it is characterized in that, said preparation comprises that also parts by weight are a kind of, two or more mixing in 2~5 parts Rhizoma Smilacis Glabrae, Flos Lonicerae, Flos Chrysanthemi Indici, Herba Senecionis Scandentis and 1~4 weight portion Alumen.
4. the Chinese medicine preparation of Candida albicans disease is infected in treatment according to claim 1, it is characterized in that, the dosage form of described Chinese medicine preparation is pill, decoction, capsule, washing liquid or spraying.
CN201310058391.8A 2013-02-25 2013-02-25 Traditional Chinese medicine preparation for treating candida albicans infection diseases Expired - Fee Related CN103070963B (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103462740A (en) * 2013-09-25 2013-12-25 桂林恒保健康用品有限公司 Condom for treating cervical erosion
CN105534372A (en) * 2016-02-05 2016-05-04 株洲千金药业股份有限公司 Urination tissue with antibacterial effect and disinfecting effect and preparation method thereof
CN105534373A (en) * 2016-02-05 2016-05-04 株洲千金药业股份有限公司 Urination tissue with antibacterial effect and disinfecting effect and preparation method thereof
CN105640409A (en) * 2016-02-05 2016-06-08 株洲千金药业股份有限公司 Urination tissue with antimicrobial and sterilizing functions and preparation method thereof
CN105727353A (en) * 2016-02-05 2016-07-06 株洲千金药业股份有限公司 Liquid medicine having bacteriostatic and sterilizing effects and application thereof
CN105902666A (en) * 2016-04-24 2016-08-31 张昌莲 Traditional Chinese medicinal composition for treating pruritus vulvae
CN106361951A (en) * 2016-10-24 2017-02-01 严成 Traditional Chinese medicine for treating chronic mucocutaneous candidiasis

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CN101274093A (en) * 2008-05-06 2008-10-01 广冬云 Chinese medicine for curing fungal dermatopathy
CN101664526A (en) * 2008-09-02 2010-03-10 陈瑞华 External Chinese medicinal lotion
JP2011088854A (en) * 2009-10-22 2011-05-06 Kao Corp Involucrin expression inhibitor

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CN1879831A (en) * 2006-05-17 2006-12-20 杨晋懿 Bacteriostatic externally applied preparation for treating gynecological inflammation and method for preparing same
CN101274093A (en) * 2008-05-06 2008-10-01 广冬云 Chinese medicine for curing fungal dermatopathy
CN101664526A (en) * 2008-09-02 2010-03-10 陈瑞华 External Chinese medicinal lotion
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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103462740A (en) * 2013-09-25 2013-12-25 桂林恒保健康用品有限公司 Condom for treating cervical erosion
CN105534372A (en) * 2016-02-05 2016-05-04 株洲千金药业股份有限公司 Urination tissue with antibacterial effect and disinfecting effect and preparation method thereof
CN105534373A (en) * 2016-02-05 2016-05-04 株洲千金药业股份有限公司 Urination tissue with antibacterial effect and disinfecting effect and preparation method thereof
CN105640409A (en) * 2016-02-05 2016-06-08 株洲千金药业股份有限公司 Urination tissue with antimicrobial and sterilizing functions and preparation method thereof
CN105727353A (en) * 2016-02-05 2016-07-06 株洲千金药业股份有限公司 Liquid medicine having bacteriostatic and sterilizing effects and application thereof
CN105534373B (en) * 2016-02-05 2018-11-16 株洲千金药业股份有限公司 It is a kind of with antibacterial, disinfection towel and preparation method thereof of going to the lavatory
CN105534372B (en) * 2016-02-05 2018-11-16 株洲千金药业股份有限公司 It is a kind of with antibacterial, disinfection towel and preparation method thereof of going to the lavatory
CN105640409B (en) * 2016-02-05 2018-11-16 株洲千金药业股份有限公司 It is a kind of with antibacterial, disinfection towel and preparation method thereof of going to the lavatory
CN105902666A (en) * 2016-04-24 2016-08-31 张昌莲 Traditional Chinese medicinal composition for treating pruritus vulvae
CN106361951A (en) * 2016-10-24 2017-02-01 严成 Traditional Chinese medicine for treating chronic mucocutaneous candidiasis

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