CN101391065B - Compound momordica seed pepper soup for treating urgent chronic pelvic inflammatory disease - Google Patents

Abstract

The invention relates to the medicine preparation field, in particular to a semen momordicae Chinese pepper soup for curing acute and chronic pelvic inflammatory diseases, which is composed of following materials: semen momordicae, phellodendron, lightyellow sophora root, tuckahoe, taraxacum, honeysuckle, dahuricae angelica root, root of herbaceous peony with bark, liquorice, corydalis tuber, coix seed and Chinese pepper; the above materials are completely prepared and added with cool water to inundate the medicine materials, and then dipped, decocted and filtered so as to prepare the soup medicine; the soup is characterized in that the materials by weight ratio are as following: 4 to 7 parts of semen momordicae, 4 to 7 parts of phellodendron, 6 to 9 parts of lightyellow sophora root, 13 to 17 parts of tuckahoe, 13 to 17 parts of taraxacum, 8 to 12 parts of honeysuckle, 1 to 4 parts of dahuricae angelica root, 5 to 9 parts of root of herbaceous peony with bark, 4 to 7 parts of liquorice, 6 to 9 parts of corydalis tuber, 13 to 17 parts of coix seed and 4 to 6 parts of Chinese pepper. The soup medicine has the advantages of low cost materials, high efficiency for curing the acute and chronic pelvic inflammatory diseases, no side effect, and improving the patient organism resistibility.

Description

A kind of momordica seed pepper soup that is used for the treatment of urgent chronic pelvic inflammatory disease

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of compound momordica seed pepper soup that is used for the treatment of women's urgent chronic pelvic inflammatory disease.

Background technology

As everyone knows, pelvic inflammatory disease is meant pelvic cavity genitals (body of uterus, fallopian tube, ovary) and pelvic peritoneum and periuterine ICT, and symptoms such as clinical appearance heating, stomachache, leucorrhoea grow in quantity are called pelvic inflammatory disease.Pelvic inflammatory disease belongs to traditional Chinese medical science “ WEIJIA ", category such as " leukorrhagia ".Chronic pelvic inflammatory disease is often failed thoroughly treatment for acute pelvic inflammatory disease, or due to the relatively poor course of disease delay of patient's body constitution, but also can not have the acute pelvic inflammatory disease medical history, as ureteritis due to the chlamydia trachomatis.The chronic pelvic inflammatory disease state of an illness is obstinate, when Abwehrkraft des Koepers is relatively poor, acute attack can be arranged.Acute pelvic inflammatory disease shows as shiver with cold, heating, abdominal pain with tenderness, fulminant leucorrhagia with yellowish discharge and increases like pus, smelly dirty, aching pain in waist and back, can there be nausea and vomiting, abdominal pain diarrhea, inflammatory masses and masses that the local compression irritation is arranged when forming during companion's peritonitis, or frequent micturition, dysurea, difficult defecation, tenesmus etc. are arranged.Chronic pelvic inflammatory disease shows as low thermal fluctuation, lower abdomen dull pain or abdominal pain with tenderness, and leukorrhagia increases, yellow skin thickness or oxious gas is arranged, the dark coloured urine constipation.Chronic pelvic inflammatory disease is because the course of disease is long, and clinical main long-term or multiple repeatedly antibiotic therapeutic alliance there is no significant curative effect sometimes, the medical expense height, and patient's thought pressure is big, becomes clinical difficult point, has had a strong impact on pelvic inflammatory disease patient's physical and mental health.

Summary of the invention

Technical problem to be solved by this invention is in order to overcome above-mentioned existing technical deficiency, to provide a kind of cost low, treat urgent chronic pelvic inflammatory disease curative effect height, have no side effect, and can strengthen patient's Abwehrkraft des Koepers, being applicable to urgent chronic pelvic inflammatory disease.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of momordica seed pepper soup that is used for the treatment of urgent chronic pelvic inflammatory disease, adopt Semen Momordicae, Cortex Phellodendri, Radix Sophorae Flavescentis, Poria, Herba Taraxaci, Flos Lonicerae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Glycyrrhizae, Rhizoma Corydalis, Semen Coicis, Pericarpium Zanthoxyli is that feedstock production forms, after medicine assorted, add cold water and cover powder, through soaking, decoct, filtration is prepared into decoction, it is characterized in that the raw material composition is by weight percentage: Semen Momordicae 4～7, Cortex Phellodendri 4～7, Radix Sophorae Flavescentis 6～9, Poria 13～17, Herba Taraxaci 13～17, gold silver～spend 8～12, the Radix Angelicae Dahuricae 1～4, Radix Paeoniae Rubra 5～9, Radix Glycyrrhizae 4～7, Rhizoma Corydalis 6～9, Semen Coicis 13～17, Pericarpium Zanthoxyli 4～6.

The invention has the beneficial effects as follows that cost of material is low, treatment urgent chronic pelvic inflammatory disease curative effect height has no side effect, and can strengthen patient's Abwehrkraft des Koepers.

The specific embodiment

The invention will be further described below in conjunction with embodiment:

Embodiment 1:

Adopting Semen Momordicae, Cortex Phellodendri, Radix Sophorae Flavescentis, Poria, Herba Taraxaci, Flos Lonicerae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Glycyrrhizae, Rhizoma Corydalis, Semen Coicis, Pericarpium Zanthoxyli is that feedstock production forms.Its component (weight %) is Semen Momordicae 4.98, Cortex Phellodendri 4.5, Radix Sophorae Flavescentis 7.49, Poria 14.9, Herba Taraxaci 14.9, Flos Lonicerae 9.95, the Radix Angelicae Dahuricae 2.99, Radix Paeoniae Rubra 7.49, Radix Glycyrrhizae 5.97, Rhizoma Corydalis 7.46, Semen Coicis 14.9, Pericarpium Zanthoxyli 4.47, getting above-mentioned 12 kinds of raw material gross weights is 402g, at ambient temperature above-mentioned 12 kinds of Chinese herbal medicine are added water to 3500ml, soaked 5～8 hours, decoct then more than 60 minutes, remove slag filtrate 1500ml, add water 1500ml again and decoct 60 minutes, remove slag filtrate 500ml, altogether medicinal liquid 2000ml.At first allow patient's emptying defecation, get the 1600ml medicinal liquid, the fumigation and wash method perineal position was treated to begin demibain when fluid temperature is reduced to 40 ℃ of left and right sides about 20 minutes while hot, once a day, and each about 30 minutes.Get the remaining 400ml of liquid after the demibain, divide twice coloclysis sooner or later, about each 200ml, patient's buttocks is raised 10 centimetres, get right arm reclining, 200 milliliters of taking liquids, 39～41 ℃ of temperature, (or disposable) No. 14 catheters with sterilization insert 15 centimetres of anal, and liquid level is lower than 30 centimetres apart from anus, keeps about 60 of per minutes, medicinal liquid was kept about 2 hours, be a course of treatment at twice, 10 day sooner or later every day, but continuous application 2--3 course of treatment.The principal agent Semen Momordicae is the mature seed of cucurbitaceous plant Semen Momordicae in of the present invention group, nature and flavor hardship, little sweet, warm, poisonous.Go into liver, spleen, stomach warp.Have the middle eliminating stagnation that disappears, the function of the poison of dispelling, can treat diseases such as epilepsy is swollen, furuncle, innominate toxic swelling, tinea skin ulcer, rheumatic arthralgia, the contracture of muscle arteries and veins.Chemical constituent contains sterol, oleanolic acid, momordic acid.By Saponin, the α that the Radix Kaki ruscogenin became--keto acid, trehalose etc.Can control that meridians have a cold that pathogen, muscle arteries and veins involve, skin pain, the poly-nucleation of knot, contracture paralysis.Control to beat and pounce on the diffusing pain of damage, blood stasis.Cortex Phellodendri nature and flavor hardship, cold is gone into kidney, urinary bladder channel.Have heat clearing away, dampness, pathogenic fire purging, antidotal function.Can treat hematodiarrhoea, have loose bowels, hemorrhoid, have blood in stool, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin etc.Water decoction or pure preserved material have in various degree inhibitory action external to staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, Diplococcus pneumoniae, escherichia coli, bacillus pyocyaneus etc., many laboratory report proof Cortex Phellodendris have stronger inhibitory action to Fu Shi, Song Nei Shi, will Hayes and Amur dysentery bacterium, tubercule bacillus also there is inhibitory action, and the tulase bacterial strain to streptomycin, aminosalicylic acid, isoniazid is also effective, also has the stronger leptospira effect of killing.Radix Sophorae Flavescentis nature and flavor hardship, tremble with fear, return liver, kidney, large intestine, small intestine meridian.Have heat clearing away, dampness, parasite killing, anticancer function, can treat toxic-heat and blood stasis, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pain over the perineum, eczema, eczema, skin pruritus, acute enteritis, bacillary dysentery, amebic dysentery, external treatment trichomonal vaginitis etc.The oxymatrine intramuscular injection is similar to the oxidation cortisone, can obviously resist the exudative inflammation that Oleum Tiglii, carrageenin (rat) and glacial acetic acid (mice) bring out, and in vitro experimental results show that it is direct inflammation-inhibiting reaction.Matrine has anti-lamb Type B clostridieum welchii and the effect of anti-sheep escherichia coli, each experimental group and the equal highly significant of matched group difference in vivo.In vitro tests proves that 1% matrine all has the obvious suppression effect to dysentery bacterium, escherichia coli, Bacillus proteus, group B streptococcus and staphylococcus aureus, and pure extractum has an anti-trichomonal effect external.Poria is the dry sclerotia of Polyporaceae fungus Poria, and nature and flavor are sweet, flat, light, GUIXIN, lung, spleen, kidney channel.Have functions such as eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming, can treat dysuria, edema distension, phlegm retention cough with dyspnea, loose stool diarrhea, irritability, stranguria with turbid discharge, insufficiency of the spleen, stop that drink is not eaten, gastral cavity is vexed, three YIN malaria (malaria pathogen in three YIN) expectorant, Yu that generates heat not etc.Antibacterial action, 100% decoct has inhibitory action with the flat board method that burrows to staphylococcus aureus, escherichia coli and Bacillus proteus, tubercule bacillus etc.Hemolytic plaque test shows has facilitation to mouse humoral immune.Herba Taraxaci is feverfew Herba Taraxaci, alkali ground Herba Taraxaci or the dry herb that belongs to several plants together.The nature and flavor hardship, sweet, tremble with fear, return liver, stomach warp.Function with heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.Control acute mastitis, lymphadenitis, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria etc.This product is a broad-spectrum antiseptic.50% the dull and stereotyped trench method of bright grass juice factor has inhibitory action to staphylococcus aureus, Bacillus typhi, bacillus pyocyaneus, and Hemolytic streptococcus, meningococcus, diphtheria corynebacterium, Bacillus proteus, dysentery bacterium etc. are had inhibitory action.Extracorporeal bacteria inhibitor test proves that TMP has antibacterial potentiation to Herba Taraxaci, and the compound dandelion bacteriostatic activity strengthens.The Ultrastructural observation Herba Taraxaci is to the structural change of staphylococcus aureus, and Herba Taraxaci can make cell expand, and cell wall thickens, and therefore karyon ribosome homopolymerization integrated package has disturbed the synthetic of RNA and DNA, the blocking-up bacterial growth.Flos Lonicerae is honeysuckle root plant Radix Ophiopogonis, the flower that the dry flower of Flos Lonicerae, Flos Lonicerae or hair style Radix Ophiopogonis or band are just opened.Nature and flavor are sweet, tremble with fear, return lung, the heart, stomach warp.Have heat-clearing and toxic substances removing, wind-heat dissipating is used for carbuncle furuncle, larynx illness, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating etc.In vitro tests proves, Flos Lonicerae all has certain inhibitory action to various pathogens such as staphylococcus aureus, Hemolytic streptococcus, escherichia coli, dysentery bacterium, vibrio cholera, Bacillus typhi, Salmonella paratyphi etc., and is also effective to streptococcus pneumoniae, bacillus pyocyaneus, tubercule bacillus.Flos Lonicerae has good antibacterial and bactericidal action to causing dental caries, Streptococcus mutans.The Flos Lonicerae decoct is diluted to 1: 1280 concentration, still can promote leukocytic phagocytic function.The Radix Angelicae Dahuricae is the dry root of the samphire Radix Angelicae Dahuricae or the anti-Radix Angelicae Dahuricae, nature and flavor suffering, temperature, returns stomach, large intestine, lung meridian.Have diffusing wind dehumidifying, understand things pain-stopping, detumescence and apocenosis, rash, antidotal function.And control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies, anemofrigid cold, anal fistula are had blood in stool, leucorrhea, carbuncle pyogenic infections from tumour or sore etc.Antibacterial action, in vitro tests, Radix Angelicae Dahuricae water decoction has certain inhibitory action to escherichia coli, dysentery bacterium, typhoid fever, Salmonella paratyphi, bacillus pyocyaneus, Bacillus proteus and vibrio cholera etc., and the water logging agent also has certain inhibitory action to pathomycetes such as Du Shi microspore's tinea bacterium difficult to understand.Radix Paeoniae Rubra is the dry root of ranunculaceae plant Radix Paeoniae, the nature and flavor hardship, is slightly cold, and returns Liver Channel.Have the function of clearing away heat and cooling blood, eliminating stasis to stop pain, be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, WEIJIA stomachache, injury from falling down, carbuncle skin infection etc.Antiinflammatory and to immune effect, Radix Paeoniae Rubra n-butanol extract 3g/kg subcutaneous injection 5 times, mice reticuloendothelial system phagocytic index significantly improves, liver weight obviously increases, the delayed hypersensitivity that chicken red blood cell is excited also has remarkable inhibitory action, and active T lymphocyte is had inhibitory action.Paeoniflorin has more weak antiinflammatory action.Radix Paeoniae Rubra and paeoniflorin can suppress rat and the motion of Cavia porcellus intestinal tube stomach function regulating, the smooth muscle spasm that anti-acetylcholine is caused, the rat uterus smooth muscle there is inhibitory action, and can resists the uterine contraction that pituitrin causes, the rat stomach anxiety that the antagonism pilocarpine causes.Radix Glycyrrhizae is the dry root and rhizome of glycyrrhizic legume Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L., nature and flavor are sweet, flat, GUIXIN, lung, spleen, stomach warp, function with invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, be used for various the swelling and ache that deficiency of QI in middle-JIAO, deficiency of vital energy blood decline, process with controlling weakness of the spleen and stomach, lack of appetite stomachache loose stool,, overstrain heating, consumptive lung disease cough, cardiopalmus, infantile convulsion, life is with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separating poison of drug and alimentary toxicosis.Antiviral and antibacterial action, Angelica Polysaccharide have tangible anti-vesicular stomatitis virus, adenovirus etc., can significantly suppress cytopathic generation, and the cell of tissue culture is protected, and the effect that has phenomenons such as promoting the corneal opacity to recover in advance.Antibacterial action, glycyrol extract and sodium glycyrrhetate all have inhibitory action external to staphylococcus aureus, tubercule bacillus, escherichia coli, ameba and infusorian, and the inflammation of chronic granulation tissue hyperplasia is also had the obvious suppression effect.To Immune Effects, can suppress the mast cell degranulation that histamine liberators's----compound 48/80 causes, thereby stop the release of crossing sensitive media, avoid the generation of anaphylactic shock, and have the effect of adrenocortical hormone sample.The stomach motion weakened gradually after spasmolysis, 10% Radix Glycyrrhizae extractum 4mg/kg were irritated stomach to rabbit, and the stomach motion almost stops after 30 minutes, and hepatoprotective effect is arranged, and the degeneration of liver and necrosis are significantly weakened.Rhizoma Corydalis is the tuber of Papaveraceae Corydalis plant Rhizoma Corydalis, northeast Rhizoma Corydalis and tooth lobe Rhizoma Corydalis.Nature and flavor suffering, hardship, wet are returned the liver spleen channel.Have invigorate blood circulation, promoting the circulation of QI, analgesic function, be used for the breast side of body, Anhui abdomen pain, amenorrhea dysmenorrhea, postpartum stagnation, treating swelling and pain by traumatic injury etc.Have analgesia, anesthesia, hypnosis, calm and stable effect.Semen Coicis is the dry mature kernal of grass Semen Coicis, and nature and flavor are sweet, light, cool, returns spleen, stomach, lung meridian.Have strong liver eliminating dampness by diuresis, remove spleen antidiarrheal, the function of clearing away heat and discharging pus, be used for edema, beriberi, dysuria, wet spleen contracture, diarrhea due to hypofunction of the spleen, lung abscess, acute appendicitis, women's leukorrhagia, rheumatic arthritis etc.To the central nervous system have calmness, suppress multisynaptic reflex, effects such as cooling and analgesic, analgesia.In vitro tests shows that Semen Coicis herb (bright product) is squeezed the juice or root (dry product) decoct has certain antibacterial action to staphylococcus aureus, beta hemolytic streptococcus, anthrax bacillus, diphtheria corynebacterium, and the Semen Coicis ethanol extraction also is a kind of effective antibacterial.Pericarpium Zanthoxyli is the peel or the seed of rutaceae Pericarpium Zanthoxyli and green pepper, and nature and flavor suffering, temperature are returned spleen, stomach, kidney channel.Function with warming middle-JIAO to relieve pain, killing parasites for relieving itching is used for the treatment of stomach abdomen cold type of pain, vomits, has loose bowels, schistosomicide, ascariasis, filaricide, and external is controlled toothache, seborrheic dermatitis, and can be done topical anesthesia and use.Analgesic activity, pepper water extract 5-10g/kg and ether extract 3-6ml/kg to ether cause mouse writhing reaction the obvious suppression effect is arranged.Antibacterial action, 100% Pericarpium Zanthoxyli decoct all has inhibitory action with dull and stereotyped little agar diffusion method to first, group B streptococcus, staphylococcus, Diplococcus pneumoniae, anthrax bacillus, diphtheria corynebacterium, vibrio cholera, Bacillus proteus, typhoid fever, Salmonella paratyphi, escherichia coli, Song Shi dysentery bacterium, bacillus pyocyaneus, gram negative bacilli etc.Volatile oil can make ascaris suum seriously poison in the ringer solution of insulation, and this may be the synergistic result with contained phellandrene, limonene, citronellol etc.All medicines share, and play the specially good effect of urgent chronic pelvic inflammatory disease altogether.

Embodiment 2:

Adopting Semen Momordicae, Cortex Phellodendri, Radix Sophorae Flavescentis, Poria, Herba Taraxaci, Flos Lonicerae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Glycyrrhizae, Rhizoma Corydalis, Semen Coicis, Pericarpium Zanthoxyli is that feedstock production forms.Its component (weight %) is Semen Momordicae 5.63, Cortex Phellodendri 4.21, Radix Sophorae Flavescentis 7.3, Poria 14.6, Herba Taraxaci 15.2, Flos Lonicerae 9.73, the Radix Angelicae Dahuricae 3.21, Radix Paeoniae Rubra 7.19, Radix Glycyrrhizae 6.27, Rhizoma Corydalis 8.09, Semen Coicis 13.9, Pericarpium Zanthoxyli 4.67 for every pair, getting above-mentioned 12 kinds of raw material gross weights is 402g, at ambient temperature above-mentioned 12 kinds of Chinese herbal medicine are added water to 3500ml, soaked 5---8 hour, decoct then more than 60 minutes, remove slag filtrate 1500ml, add water 1500ml again and decoct 60 minutes, remove slag filtrate 500ml, altogether medicinal liquid 2000ml.At first allow patient's emptying defecation, get the 1600ml medicinal liquid, the fumigation and wash method perineal position was treated to begin demibain when fluid temperature is reduced to 40 ℃ of left and right sides about 20 minutes while hot, once a day, and each about 30 minutes.Get the remaining 400ml of liquid after the demibain, divide twice coloclysis sooner or later, about each 200ml.Patient's buttocks is raised 10 centimetres, get right arm reclining, 200 milliliters of taking liquids, 39～41 ℃ of temperature are with (or disposable) No. 14 catheters insertions anal 15cm of sterilization, liquid level is lower than 30cm apart from anus, keep about 60 of per minutes, medicinal liquid was kept about 2 hours, twice sooner or later of every day, 10 days is a course of treatment, but continuous application 2--3 course of treatment.

This kind of the present invention compound momordica seed pepper soup is people and different due to illness, only adjust the addition of Semen Momordicae, Cortex Phellodendri, Radix Sophorae Flavescentis, Poria, Herba Taraxaci, Flos Lonicerae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Glycyrrhizae, Rhizoma Corydalis, Semen Coicis, Pericarpium Zanthoxyli 12 flavor Chinese herbal medicine, its processing method and embodiment 1 or embodiment 2 are basic identical, but each raw material also the blended embodiment of the listed ratio of according to the form below (percentage by weight) realize.

Below in conjunction with my institute, promptly the clinical preliminary test that carries out of Shandong Province Wendeng Central Hospital, Weihai City is done further, is described in detail the present invention:

1, case is selected: this organizes 60 examples, woman.Age 21-30 year, 10 examples, age 31-40 year, 30 examples, age 41-50 year, 20 examples; 43 examples of wherein suffering from the chronic pelvic inflammatory disease disease are suffered from sick 17 examples of acute pelvic inflammatory disease.

2, Therapeutic Method: at first allow patient's emptying defecation, get the 1600ml medicinal liquid, the fumigation and wash method perineal position was treated to begin demibain when fluid temperature is reduced to 40 ℃ of left and right sides about 20 minutes while hot, once a day, and each about 30 minutes.Get the remaining 400ml of liquid after the demibain, divide twice coloclysis sooner or later, about each 200ml, patient's buttocks is raised 10 centimetres, get right arm reclining, 200 milliliters of taking liquids, 39～41 ℃ of temperature, (or disposable) No. 14 catheters with sterilization insert 15 centimetres of anal, and liquid level is lower than 30 centimetres apart from anus, keeps about 60 of per minutes, medicinal liquid was kept about 2 hours, be a course of treatment at twice, 10 day sooner or later every day, 3 courses of treatment of continuous application.

3, therapeutic effect: use the present invention to treat 60 examples altogether, produce effects 18 examples as a result, effective 40 examples, invalid 2 examples, obvious effective rate 30 is % as a result, and effective percentage is 67%, and inefficiency is 3%, and total effective rate is 97%.

Claims (1)

1. momordica seed pepper soup that is used for the treatment of urgent chronic pelvic inflammatory disease, adopt Semen Momordicae, Cortex Phellodendri, Radix Sophorae Flavescentis, Poria, Herba Taraxaci, Flos Lonicerae, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Radix Glycyrrhizae, Rhizoma Corydalis, Semen Coicis, Pericarpium Zanthoxyli is that feedstock production forms, after medicine assorted, add cold water and cover powder, through soaking, decoct, filtration is prepared into decoction, it is characterized in that: the raw material composition is Semen Momordicae 4～7 by weight percentage, Cortex Phellodendri 4～7, Radix Sophorae Flavescentis 6～9, Poria 13～17, Herba Taraxaci 13～17, Flos Lonicerae 8～12, the Radix Angelicae Dahuricae 1～4, Radix Paeoniae Rubra 5～9, Radix Glycyrrhizae 4～7, Rhizoma Corydalis 6～9, Semen Coicis 13～17, Pericarpium Zanthoxyli 4～6.