CN104587202A - Traditional Chinese medicine ointment for treating eczema and preparation method traditional Chinese medicine ointment - Google Patents

Traditional Chinese medicine ointment for treating eczema and preparation method traditional Chinese medicine ointment Download PDF

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CN104587202A
CN104587202A CN201510031059.1A CN201510031059A CN104587202A CN 104587202 A CN104587202 A CN 104587202A CN 201510031059 A CN201510031059 A CN 201510031059A CN 104587202 A CN104587202 A CN 104587202A
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radix
chinese medicinal
rhizoma
eczema
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张雪英
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Abstract

The invention discloses a traditional Chinese medicine ointment for treating eczema and a preparation method of the traditional Chinese medicine ointment, relating to the field of medicaments for treating eczema, and mainly solving the problems that the existing medicine for treating eczema is incapable of treating both symptoms and root causes and has side effects. The traditional Chinese medicine ointment is prepared from the following bulk pharmaceutical chemicals as active ingredients in parts by mass: 6-27 parts of rhizoma dioscoreae hypoglaucae, 12-25 parts of cortex dictamni, 6-29 parts of herba schizonepetae, 13-32 parts of fructus malvae, 9-24 parts of radix saposhnikoviae, 17-31 parts of juncus, 11-26 parts of exocarpium benincasae, 6-23 parts of radix angelicae sinensis, 12-27 parts of radix cyathulae, 11-28 parts of radix rehmanniae recens, 6-21 parts of flos sophorae, 8-29 parts of herba taraxaci, 11-31 parts of radix paeoniae rubra, 5-26 parts of radix angelicae dahuricae, 13-32 parts of rhizoma atractylodis macrocephalae, 9-23 parts of rhizoma bletillae, 8-24 parts of radix astragali seu hedysari, 11-26 parts of radix sophorae flavescentis, 5-27 parts of radix ampelopsis and 15-30 parts of radix glycyrrhizae. The traditional Chinese medicine ointment can promote the elimination of eczema syndromes, and the total effective rate for treating eczema can achieve more than 98%.

Description

A kind of Chinese medicinal ointment for the treatment of eczema and preparation method thereof
Technical field
The present invention relates to treatment eczema technical field of pharmaceuticals, specifically a kind of Chinese medicinal ointment for the treatment of eczema and preparation method thereof.
Background technology
Eczema is a kind of scytitis reaction of the acute pruritus caused by multiple internal and external factor.The traditional Chinese medical science thinks that primary disease is mainly due to retention of damp-heat in the interior, innate excess of YANG in the body, the dry domination of wind of blood, spleen asthenia and dampness retention, emptiness of spleen and stomach, often paddle and soak in addition, damp pathogen being sticky and stagnant in nature gathers in the flesh natural fibre line of meat, impact is defended gas a surname and is sent out, and battalion defends and becomes estranged, hematogenous blockage, defend not solid outward, be subject to the heresy invasion of wind heat, wet and wind, hot three heresies are fought mutually and are tied, and fill in the flesh natural fibre line of meat, contamination skin, sends out as eczema.The clinical manifestation of eczema is varied, can be erythema, pimple, swelling, vesicle, erosion, ooze out, form a scab, squama, infiltration, plumpness and the multiple skin lesion such as to chap.Current doctor trained in Western medicine there is no specific short to eczema, many employings are with antihistamine drug for oral administration, hormone medicine suppresses for many temporarily, as oral western medicine, and oral hormone, externally-applied ointment, Emulsion, liniment, tincture and plaster etc., but can only relief of symptoms, can not effect a radical cure, and there is certain side effect, thus add treatment difficulty, use exists certain drawback.
Summary of the invention
The object of the invention is, in order to overcome the above problems, to provide a kind for the treatment of both the principal and secondary aspects of a disease, the Chinese medicinal ointment of the treatment eczema had no side effect.
The technical solution used in the present invention is: a kind of Chinese medicinal ointment for the treatment of eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 6 ~ 27 parts, Cortex Dictamni 12 ~ 25 parts, Herba Schizonepetae 6 ~ 29 parts, Semen Abutili 13 ~ 32 parts, Radix Saposhnikoviae 9 ~ 24 parts, Medulla Junci 17 ~ 31 parts, Exocarpium Benincasae 11 ~ 26 parts, Radix Angelicae Sinensis 6 ~ 23 parts, Radix Cyathulae 12 ~ 27 parts, 11 ~ 28 parts, the Radix Rehmanniae, 6 ~ 21 parts, Flos Sophorae, Herba Taraxaci 8 ~ 29 parts, Radix Paeoniae Rubra 11 ~ 31 parts, the Radix Angelicae Dahuricae 5 ~ 26 parts, the Rhizoma Atractylodis Macrocephalae 13 ~ 32 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 9 ~ 23 parts, the Radix Astragali 8 ~ 24 parts, Radix Sophorae Flavescentis 11 ~ 26 parts, Radix Ampelopsis 5 ~ 27 parts, 15 ~ 30 parts, Radix Glycyrrhizae.
Further, a kind of Chinese medicinal ointment for the treatment of eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 10 ~ 22 parts, Cortex Dictamni 17 ~ 20 parts, Herba Schizonepetae 11 ~ 22 parts, Semen Abutili 18 ~ 26 parts, Radix Saposhnikoviae 13 ~ 20 parts, Medulla Junci 23 ~ 28 parts, Exocarpium Benincasae 18 ~ 23 parts, Radix Angelicae Sinensis 14 ~ 19 parts, Radix Cyathulae 17 ~ 20 parts, 16 ~ 20 parts, the Radix Rehmanniae, 12 ~ 18 parts, Flos Sophorae, Herba Taraxaci 13 ~ 20 parts, Radix Paeoniae Rubra 16 ~ 26 parts, the Radix Angelicae Dahuricae 12 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 18 ~ 27 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 12 ~ 19 parts, the Radix Astragali 14 ~ 19 parts, Radix Sophorae Flavescentis 17 ~ 23 parts, Radix Ampelopsis 14 ~ 20 parts, 20 ~ 25 parts, Radix Glycyrrhizae.
Further, treat a Chinese medicinal ointment for eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 16 parts, Cortex Dictamni 18 parts, Herba Schizonepetae 17 parts, Semen Abutili 23 parts, Radix Saposhnikoviae 17 parts, Medulla Junci 25 parts, Exocarpium Benincasae 20 parts, Radix Angelicae Sinensis 16 parts, Radix Cyathulae 18 parts, 17 parts, the Radix Rehmanniae, 15 parts, Flos Sophorae, Herba Taraxaci 17 parts, Radix Paeoniae Rubra 20 parts, the Radix Angelicae Dahuricae 17 parts, the Rhizoma Atractylodis Macrocephalae 22 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, the Radix Astragali 17 parts, Radix Sophorae Flavescentis 21 parts, Radix Ampelopsis 17 parts, 22 parts, Radix Glycyrrhizae.
The present invention also comprises a kind of preparation method for the treatment of the Chinese medicinal ointment of eczema, and described preparation method concrete steps are as follows: crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch, crude drug Radix Angelicae Sinensis according to crude drug and Pulvis concha Mactrae weight ratio, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, and brine strength is 20%, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae is that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, is mixed by the feed components after processing, grinds, cross 70 mesh sieves and obtain coarse powder, in coarse powder, add the clear water leaching coarse powder 1 ~ 3cm, decoct to obtain decoction liquor, by decoction liquor through 16 layers of filtered through gauze, filtrate concentrates at outer circulation concentrator, concentrated condition is: pressure 0.03Mpa, temperature 70 C, is concentrated into the extractum that relative density is 1.13 ~ 1.14, high temperature sterilize, obtains described Chinese medicinal ointment.
Using method: adult every day 2 times for affected part, sooner or later each once, within 5 days, be a course for the treatment of.
Medical material effect of the present invention is resolved as follows:
Rhizoma Dioscoreae Septemlobae bitter in the mouth, property is put down, and have dampness removing and go turbid, effect of wind expelling stagnation removing, is mainly used in stranguria marked by chyluria, nebulousurine, leukorrhagia, rheumatic arthralgia, articular instability, lumbocrural pain.Cortex Dictamni bitter in the mouth, cold in nature, have heat clearing and damp drying, the effect of removing toxic substances of dispeling the wind, the damp and hot sore of primary treatment, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia.Herba Schizonepetae acrid in the mouth, slightly warm in nature, have the loose wind that induces sweat, rash, the effect of the skin ulcer that disappears, primary treatment be used for flu, headache, measles, rubella, skin infection from the beginning of.Semen Abutili sweet in the mouth, cold in nature, there is effect of relieving stranguria by diuresis, clearing away heat-damp and promoting diuresis, detumescence, primary treatment urinary obstruction, urinary tract infection, urinary system calculus, lack of lactation after delivery.Radix Saposhnikoviae acrid in the mouth, sweet, slightly warm in nature, has expelling pathogenic wind from the body surface, removing dampness to relieve pain, effect of relieving convulsion, primary treatment diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus just, insufficiency of the spleen leading to overabundance of dampness.Medulla Junci sweet in the mouth, slightly warm in nature, has clearing away heart-fire, effect of diuresis, and primary treatment is used for vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue.Exocarpium Benincasae sweet in the mouth, cool in nature, have the effect of inducing diuresis to remove edema, primary treatment edema distension, dysuria, summer-heat is thirsty, oliguria with reddish urine.Radix Angelicae Sinensis acrid in the mouth, sweet, warm in nature, have and enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, be mainly used in that menoxenia, amenorrhea, dysmenorrhea, lump in the abdomen knot are poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, weight, ulcer sores, injury from falling down after bloody dysentery.Radix Cyathulae sweet in the mouth, property is put down, and has eliminating blood stasis and inducing menstruation, easing joint movement, effect of inducing diuresis for treating stranguria syndrome, is mainly used in amenorrhea lump in the abdomen, retention of placenta, injury from falling down, rheumatic arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, the diseases such as hematuria stranguria with blood.Radix Rehmanniae sweet in the mouth, cold, warm in nature, there is clearing away heat and cooling blood, effect that tonifying YIN promotes the production of body fluid, be mainly used in warm febrile disease and join the army blood, high fever coma, xerostomia crimson tongue.Flos Sophorae bitter in the mouth, cold nature, has cooling blood for hemostasis, effect of purging liver-fire, be mainly used in having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, haematemesis, epistaxis, liver-heat conjunctival congestion, the disease such as to have a headache dizzy.Herba Taraxaci sweet in the mouth, cold in nature, there is the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting, be mainly used in pyretic toxicity, carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Radix Paeoniae Rubra bitter in the mouth, cold nature, has clearing away heat and cooling blood, effect of eliminating stasis to stop pain, is mainly used in thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass stomachache, injury from falling down, carbuncle skin infection.Radix Angelicae Dahuricae acrid in the mouth, warm in nature, have the cold expelling that induces sweat, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis, effect of dispelling wind for relieving itching, is mainly used in anemofrigid cold, headache, toothache, rheumatic arthralgia, and nasal sinusitis, leukorrhagia is demonstrate,proved, sore and toxic.Rhizoma Atractylodis Macrocephalae bitter in the mouth, warm in nature, there is invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, insufficiency of the spleen lack of appetite can be controlled, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Pseudobulbus Bletillae (Rhizoma Bletillae) bitter in the mouth, cold nature, has astringing to arrest bleeding, the effect of detumescence and promoting granulation, is mainly used in spitting of blood, spits blood, traumatic hemorrhage, sore swollen toxin, chapped skin.Radix Astragali sweet in the mouth, slightly warm in nature, has effect of benefiting QI for strengthening the superficies, promoting pus discharge and tissue regeneration strengthening, be mainly used in enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Radix Sophorae Flavescentis bitter in the mouth, warm in nature, there is effect of heat clearing and damp drying, parasite killing, diuresis, be mainly used in hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.Radix Ampelopsis bitter in the mouth, cold nature, has heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, and effect of expelling pus and promoting granulation is mainly used in carbuncle carbuncle on the back, furuncle, scrofula, burn and scald.Radix Glycyrrhizae sweet in the mouth, property are flat, and it contains number of chemical composition, and effect is replenishing QI to invigorate the spleen, expelling phlegm for arresting cough, heat-clearing and toxic substances removing, relieving spasm to stop pain.
The present invention has following beneficial effect: Chinese medicinal ointment of the present invention adopts pure Chinese medicinal preparation, effectively overcomes the toxic and side effects of Western medicine preparation, each crude drug effective ingredient synergism, can treating both the principal and secondary aspects of a disease eczema, treats safe and effective, has no adverse reaction, specifically:
(1) Rhizoma Dioscoreae Septemlobae dampness removing goes turbid, Cortex Dictamni heat clearing and damp drying, Herba Schizonepetae induces sweat loose wind, Semen Abutili clearing away heat-damp and promoting diuresis, Exocarpium Benincasae treatment edema distension, effectively can treat retention of damp-heat in the interior; Chinese angelica blood supplementing is invigorated blood circulation, Radix Cyathulae eliminating blood stasis and inducing menstruation, Radix Rehmanniae clearing away heat and cooling blood, Flos Sophorae cooling blood for hemostasis, Herba Taraxaci heat clearing and blood cooling, Radix Paeoniae Rubra eliminating stasis to stop pain, can effectively treat dry wind blood victory, soothing the channels and quicking the network vessels; Radix Angelicae Dahuricae dampness leukorrhagia stopping, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic, Pseudobulbus Bletillae (Rhizoma Bletillae) detumescence and promoting granulation, Radix Astragali benefiting QI for strengthening the superficies, promoting pus discharge and tissue regeneration strengthening, Radix Sophorae Flavescentis heat clearing and damp drying, Radix Ampelopsis expelling pus and promoting granulation, Radix Glycyrrhizae replenishing QI to invigorate the spleen, can effectively promoting pus discharge and tissue regeneration strengthening, promoting blood circulation to restore menstrual flow; Medulla Junci, Cortex Dictamni, Radix Saposhnikoviae, Herba Taraxaci, the mutual compatibility of the Rhizoma Atractylodis Macrocephalae, effectively can suppress the pathogenic bacteria such as skin staphylococcus aureus, staphylococcus epidermidis, Hemolytic Type streptococcus causing eczema, and other Chinese medicines can increase the bactericidal effect of Medulla Junci, Cortex Dictamni, Radix Saposhnikoviae, Herba Taraxaci, the Rhizoma Atractylodis Macrocephalae, drug matching is suitable for, treating both the principal and secondary aspects of a disease, and medical material is easy to get.
(2) crude drug crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch according to crude drug and Pulvis concha Mactrae weight ratio, medicine is made to be convenient to preparation and adjustment, reduce the property that the taste of medicine is greasy, correct bad smell, the clearing heat and expelling damp effect of medicine can be strengthened, crude drug Radix Angelicae Sinensis, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, brine strength is 20%, saline is fried afterwards and medicine plays synergism, medicine heat clearing and blood cooling curative effect can be strengthened, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae are that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, smoke the effect that stir-fry can strengthen scattered silt pain relieving, removing the necrotic tissue and promoting granulation, can give full play to the effectiveness of medicine through Testa Tritici, grind and can promote cell rupture, middle the effective elements of the medicine is freely flowed out, is conducive to follow-up concentration extraction.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further elaborated.
Embodiment 1:
Treat a Chinese medicinal ointment for eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 6 parts, Cortex Dictamni 12 parts, Herba Schizonepetae 6 parts, Semen Abutili 13 parts, Radix Saposhnikoviae 9 parts, Medulla Junci 17 parts, Exocarpium Benincasae 11 parts, Radix Angelicae Sinensis 6 parts, Radix Cyathulae 12 parts, 11 parts, the Radix Rehmanniae, 6 parts, Flos Sophorae, Herba Taraxaci 8 parts, Radix Paeoniae Rubra 11 parts, the Radix Angelicae Dahuricae 5 parts, the Rhizoma Atractylodis Macrocephalae 13 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 9 parts, the Radix Astragali 8 parts, Radix Sophorae Flavescentis 11 parts, Radix Ampelopsis 5 parts, 15 parts, Radix Glycyrrhizae.
Crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch according to crude drug and Pulvis concha Mactrae weight ratio, crude drug Radix Angelicae Sinensis, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, brine strength is 20%, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae is that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, feed components after process is mixed, grind, cross 70 mesh sieves and obtain coarse powder, the clear water leaching coarse powder 3cm is added in coarse powder, decoct to obtain decoction liquor, by decoction liquor through 16 layers of filtered through gauze, filtrate concentrates at outer circulation concentrator, concentrated condition is: pressure 0.03Mpa, temperature 70 C, be concentrated into the extractum that relative density is 1.13, high temperature sterilize, obtain described Chinese medicinal ointment.
Embodiment 2:
Treat a Chinese medicinal ointment for eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 27 parts, Cortex Dictamni 25 parts, Herba Schizonepetae 29 parts, Semen Abutili 32 parts, Radix Saposhnikoviae 24 parts, Medulla Junci 31 parts, Exocarpium Benincasae 26 parts, Radix Angelicae Sinensis 23 parts, Radix Cyathulae 27 parts, 28 parts, the Radix Rehmanniae, 21 parts, Flos Sophorae, Herba Taraxaci 29 parts, Radix Paeoniae Rubra 31 parts, the Radix Angelicae Dahuricae 26 parts, the Rhizoma Atractylodis Macrocephalae 32 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 23 parts, the Radix Astragali 24 parts, Radix Sophorae Flavescentis 26 parts, Radix Ampelopsis 27 parts, 30 parts, Radix Glycyrrhizae.
Crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch according to crude drug and Pulvis concha Mactrae weight ratio, crude drug Radix Angelicae Sinensis, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, brine strength is 20%, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae is that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, feed components after process is mixed, grind, cross 70 mesh sieves and obtain coarse powder, the clear water leaching coarse powder 1cm is added in coarse powder, decoct to obtain decoction liquor, by decoction liquor through 16 layers of filtered through gauze, filtrate concentrates at outer circulation concentrator, concentrated condition is: pressure 0.03Mpa, temperature 70 C, be concentrated into the extractum that relative density is 1.13, high temperature sterilize, obtain described Chinese medicinal ointment.
Embodiment 3:
Treat a Chinese medicinal ointment for eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 10 parts, Cortex Dictamni 17 parts, Herba Schizonepetae 11 parts, Semen Abutili 18 parts, Radix Saposhnikoviae 13 parts, Medulla Junci 23 parts, Exocarpium Benincasae 18 parts, Radix Angelicae Sinensis 14 parts, Radix Cyathulae 17 parts, 16 parts, the Radix Rehmanniae, 12 parts, Flos Sophorae, Herba Taraxaci 13 parts, Radix Paeoniae Rubra 16 parts, the Radix Angelicae Dahuricae 12 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, the Radix Astragali 14 parts, Radix Sophorae Flavescentis 17 parts, Radix Ampelopsis 14 parts, 20 parts, Radix Glycyrrhizae.
Crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch according to crude drug and Pulvis concha Mactrae weight ratio, crude drug Radix Angelicae Sinensis, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, brine strength is 20%, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae is that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, feed components after process is mixed, grind, cross 70 mesh sieves and obtain coarse powder, the clear water leaching coarse powder 2cm is added in coarse powder, decoct to obtain decoction liquor, by decoction liquor through 16 layers of filtered through gauze, filtrate concentrates at outer circulation concentrator, concentrated condition is: pressure 0.03Mpa, temperature 70 C, be concentrated into the extractum that relative density is 1.14, high temperature sterilize, obtain described Chinese medicinal ointment.
Embodiment 4:
Treat a Chinese medicinal ointment for eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 22 parts, Cortex Dictamni 20 parts, Herba Schizonepetae 22 parts, Semen Abutili 26 parts, Radix Saposhnikoviae 20 parts, Medulla Junci 28 parts, Exocarpium Benincasae 23 parts, Radix Angelicae Sinensis 19 parts, Radix Cyathulae 20 parts, 20 parts, the Radix Rehmanniae, 18 parts, Flos Sophorae, Herba Taraxaci 20 parts, Radix Paeoniae Rubra 26 parts, the Radix Angelicae Dahuricae 20 parts, the Rhizoma Atractylodis Macrocephalae 27 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 19 parts, the Radix Astragali 19 parts, Radix Sophorae Flavescentis 23 parts, Radix Ampelopsis 20 parts, 25 parts, Radix Glycyrrhizae.
Crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch according to crude drug and Pulvis concha Mactrae weight ratio, crude drug Radix Angelicae Sinensis, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, brine strength is 20%, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae is that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, feed components after process is mixed, grind, cross 70 mesh sieves and obtain coarse powder, the clear water leaching coarse powder 3cm is added in coarse powder, decoct to obtain decoction liquor, by decoction liquor through 16 layers of filtered through gauze, filtrate concentrates at outer circulation concentrator, concentrated condition is: pressure 0.03Mpa, temperature 70 C, be concentrated into the extractum that relative density is 1.14, high temperature sterilize, obtain described Chinese medicinal ointment.
Embodiment 5:
Treat a Chinese medicinal ointment for eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 16 parts, Cortex Dictamni 18 parts, Herba Schizonepetae 17 parts, Semen Abutili 23 parts, Radix Saposhnikoviae 17 parts, Medulla Junci 25 parts, Exocarpium Benincasae 20 parts, Radix Angelicae Sinensis 16 parts, Radix Cyathulae 18 parts, 17 parts, the Radix Rehmanniae, 15 parts, Flos Sophorae, Herba Taraxaci 17 parts, Radix Paeoniae Rubra 20 parts, the Radix Angelicae Dahuricae 17 parts, the Rhizoma Atractylodis Macrocephalae 22 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, the Radix Astragali 17 parts, Radix Sophorae Flavescentis 21 parts, Radix Ampelopsis 17 parts, 22 parts, Radix Glycyrrhizae.
Crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch according to crude drug and Pulvis concha Mactrae weight ratio, crude drug Radix Angelicae Sinensis, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, brine strength is 20%, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae is that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, feed components after process is mixed, grind, cross 70 mesh sieves and obtain coarse powder, the clear water leaching coarse powder 2cm is added in coarse powder, decoct to obtain decoction liquor, by decoction liquor through 16 layers of filtered through gauze, filtrate concentrates at outer circulation concentrator, concentrated condition is: pressure 0.03Mpa, temperature 70 C, be concentrated into the extractum that relative density is 1.13, high temperature sterilize, obtain described Chinese medicinal ointment.
Embodiment 6:
Treat a Chinese medicinal ointment for eczema, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 21 parts, Cortex Dictamni 18 parts, Herba Schizonepetae 22 parts, Semen Abutili 13 parts, Radix Saposhnikoviae 19 parts, Medulla Junci 24 parts, Exocarpium Benincasae 16 parts, Radix Angelicae Sinensis 17 parts, Radix Cyathulae 20 parts, 25 parts, the Radix Rehmanniae, 21 parts, Flos Sophorae, Herba Taraxaci 23 parts, Radix Paeoniae Rubra 15 parts, the Radix Angelicae Dahuricae 5 parts, the Rhizoma Atractylodis Macrocephalae 29 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, the Radix Astragali 16 parts, Radix Sophorae Flavescentis 19 parts, Radix Ampelopsis 20 parts, 15 parts, Radix Glycyrrhizae.
Crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch according to crude drug and Pulvis concha Mactrae weight ratio, crude drug Radix Angelicae Sinensis, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, brine strength is 20%, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae is that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, feed components after process is mixed, grind, cross 70 mesh sieves and obtain coarse powder, the clear water leaching coarse powder 3cm is added in coarse powder, decoct to obtain decoction liquor, by decoction liquor through 16 layers of filtered through gauze, filtrate concentrates at outer circulation concentrator, concentrated condition is: pressure 0.03Mpa, temperature 70 C, be concentrated into the extractum that relative density is 1.13, high temperature sterilize, obtain described Chinese medicinal ointment.
Bacteriostatic test checks
Crude drug Medulla Junci 17 parts, Cortex Dictamni 12 parts, Radix Saposhnikoviae 9 parts, Herba Taraxaci 8 parts, the preparation method of the Rhizoma Atractylodis Macrocephalae 13 parts employing described in embodiment 1, obtained Chinese medicinal ointment A is as contrast, and embodiment 1 gained Chinese medicinal ointment B is that experimental group carries out antibacterial inspection.
The preparation of culture medium: take in the water-soluble 800mL of beef extract 5g, adds peptone 10g and dissolves, and adds casein 34g and dissolves, then adds NaCl 5g and dissolve, and is adjusted to pH7.6 ~ 7.8, is diluted to 1000mL.Add agar powder 18g, autoclaving 15min, when being cooled to 40 DEG C ~ 50 DEG C, a kind of rhyme scheme in Chinese operas serving as the prelude to a complete score for voices, solidifies, and the 4 DEG C of refrigerators placing no bacteria pollution are for subsequent use.
Strain is: staphylococcus aureus, staphylococcus epidermidis, Hemolytic Type streptococcus.
Matched group antibacterial liquid is prepared: be dissolved in respectively in 10ml sterile deionized water by 3 parts of 5g Chinese medicinal ointment A, diluted respectively by liquor strength, with stock solution than being 1:2,1:4,1:8,1:16,1:32.
Experimental group antibacterial liquid is prepared: get 3 parts of 5g Chinese medicinal ointment B and be dissolved in respectively in 10ml sterile deionized water, diluted respectively by liquor strength, with stock solution than being 1:2,1:4,1:8,1:16,1:32.
Staphylococcus aureus result:
Staphylococcus epidermidis result:
Hemolytic Type streptococcus result:
Result of the test shows, Chinese medicinal ointment B of the present invention has better bactericidal effect than Chinese medicinal ointment A, shows that Chinese medicine mutual compatibility fungistatic effect is better.Clinical data and case:
In order to show therapeutic effect of the present invention, system clinical observation treatment being carried out to 100 routine eczema patients, in the process of above-mentioned clinical observation, record being carried out to the medical history of above-mentioned patient, the state of an illness and curative effect.
Clinical therapeutic efficacy criterion is:
Cure: common symptom has pimple, papulovesicle or phlysis, erubescence, pruritus, and fever of the body is vexed, thirsty, constipation, and red urine is few, skin lesion flushing, pale tongue, corpulent tongue, tongue fur is white, deep-thready pulse or deep and slow etc. all to disappear.
Take a turn for the better: common sympton skin has pimple, papulovesicle or phlysis, erubescence, pruritus, and fever of the body is vexed, thirsty, constipation, and red urine is few, skin lesion flushing, pale tongue, corpulent tongue, tongue fur is white, and deep-thready pulse or deep and slow etc. disappears substantially.
Invalid: symptom is not improved.
Therapeutic effect: the present invention treats through 100 routine eczema patients, 81 examples are fully recovered, and 17 examples take a turn for the better, and 2 examples are invalid, and total effective rate reaches 98%, and nobody occurs untoward reaction, to recovery from illness follow-up of patients nothing recurrence in a year.
Model case:
Case 1: patient Jiang, female, 1 years old, patient's constipation, red urine is few, skin lesion flushing, mild swelling, then miliaria is in blocks or vesicle is intensive, sepage stream Tianjin, and pruritus is more than, red tongue, tongue fur is white, stringy and rolling pulse, after using 2 courses for the treatment of of Chinese medicinal ointment of the present invention, symptom obviously alleviates, and continues 1 course for the treatment of of use, symptom disappears completely, follows up a case by regular visits to and does not recur for 1 year.
Case 2: patient Lee, man, 17 years old, the coarse plumpness of lesions of patients had a small amount of sepage concurrently, skin lesion has pimple, papulovesicle and phlysis, skin is slight flushing, pruritus, the tired symptom of body, after using 3 courses for the treatment of of Chinese medicinal ointment of the present invention, symptom disappears completely, follows up a case by regular visits to and does not recur for 1 year.
Case 3: patient Jiang, female, 32 years old, the coarse plumpness of lesions of patients, keratinization are chapped, and there are scratch, blood crusts in surface, darker in color, pale tongue, corpulent tongue, tongue fur is white, after using 1 course for the treatment of of Chinese medicinal ointment of the present invention, symptom obviously alleviates, after continuing to use 2 courses for the treatment of of Chinese medicinal ointment of the present invention, malaise symptoms disappears completely, follows up a case by regular visits to and does not recur for 1 year.

Claims (4)

1. treat the Chinese medicinal ointment of eczema for one kind, it is characterized in that, the active ingredient raw materials medicine mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 6 ~ 27 parts, Cortex Dictamni 12 ~ 25 parts, Herba Schizonepetae 6 ~ 29 parts, Semen Abutili 13 ~ 32 parts, Radix Saposhnikoviae 9 ~ 24 parts, Medulla Junci 17 ~ 31 parts, Exocarpium Benincasae 11 ~ 26 parts, Radix Angelicae Sinensis 6 ~ 23 parts, Radix Cyathulae 12 ~ 27 parts, 11 ~ 28 parts, the Radix Rehmanniae, 6 ~ 21 parts, Flos Sophorae, Herba Taraxaci 8 ~ 29 parts, Radix Paeoniae Rubra 11 ~ 31 parts, the Radix Angelicae Dahuricae 5 ~ 26 parts, the Rhizoma Atractylodis Macrocephalae 13 ~ 32 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 9 ~ 23 parts, the Radix Astragali 8 ~ 24 parts, Radix Sophorae Flavescentis 11 ~ 26 parts, Radix Ampelopsis 5 ~ 27 parts, 15 ~ 30 parts, Radix Glycyrrhizae.
2. a kind of Chinese medicinal ointment for the treatment of eczema according to claim 1, it is characterized in that, the effective ingredient mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 10 ~ 22 parts, Cortex Dictamni 17 ~ 20 parts, Herba Schizonepetae 11 ~ 22 parts, Semen Abutili 18 ~ 26 parts, Radix Saposhnikoviae 13 ~ 20 parts, Medulla Junci 23 ~ 28 parts, Exocarpium Benincasae 18 ~ 23 parts, Radix Angelicae Sinensis 14 ~ 19 parts, Radix Cyathulae 17 ~ 20 parts, 16 ~ 20 parts, the Radix Rehmanniae, 12 ~ 18 parts, Flos Sophorae, Herba Taraxaci 13 ~ 20 parts, Radix Paeoniae Rubra 16 ~ 26 parts, the Radix Angelicae Dahuricae 12 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 18 ~ 27 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 12 ~ 19 parts, the Radix Astragali 14 ~ 19 parts, Radix Sophorae Flavescentis 17 ~ 23 parts, Radix Ampelopsis 14 ~ 20 parts, 20 ~ 25 parts, Radix Glycyrrhizae.
3. a kind of Chinese medicinal ointment for the treatment of eczema according to claim 1, it is characterized in that, the effective ingredient mass fraction making Chinese medicinal ointment is: Rhizoma Dioscoreae Septemlobae 16 parts, Cortex Dictamni 18 parts, Herba Schizonepetae 17 parts, Semen Abutili 23 parts, Radix Saposhnikoviae 17 parts, Medulla Junci 25 parts, Exocarpium Benincasae 20 parts, Radix Angelicae Sinensis 16 parts, Radix Cyathulae 18 parts, 17 parts, the Radix Rehmanniae, 15 parts, Flos Sophorae, Herba Taraxaci 17 parts, Radix Paeoniae Rubra 20 parts, the Radix Angelicae Dahuricae 17 parts, the Rhizoma Atractylodis Macrocephalae 22 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts, the Radix Astragali 17 parts, Radix Sophorae Flavescentis 21 parts, Radix Ampelopsis 17 parts, 22 parts, Radix Glycyrrhizae.
4. treat a preparation method for the Chinese medicinal ointment of eczema, it is characterized in that, concrete steps are as follows: crude drug Rhizoma Dioscoreae Septemlobae, Cortex Dictamni, Herba Schizonepetae, Semen Abutili, Radix Saposhnikoviae, Medulla Junci, Exocarpium Benincasae is that 2:1 adds Pulvis concha Mactrae and carries out parch, crude drug Radix Angelicae Sinensis according to crude drug and Pulvis concha Mactrae weight ratio, Radix Cyathulae, the Radix Rehmanniae, Flos Sophorae, Herba Taraxaci, Radix Paeoniae Rubra carries out salt stir-fry according to crude drug and weight saline than for 50:1 adds saline, and brine strength is 20%, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Astragali, Radix Sophorae Flavescentis, Radix Ampelopsis, Radix Glycyrrhizae is that 10:1 adds Testa Tritici and carries out smoked stir-fry according to crude drug and Testa Tritici weight ratio, is mixed by the feed components after processing, grinds, cross 70 mesh sieves and obtain coarse powder, in coarse powder, add the clear water leaching coarse powder 1 ~ 3cm, decoct to obtain decoction liquor, by decoction liquor through 16 layers of filtered through gauze, filtrate concentrates at outer circulation concentrator, concentrated condition is: pressure 0.03Mpa, temperature 70 C, is concentrated into the extractum that relative density is 1.13 ~ 1.14, high temperature sterilize, obtains described Chinese medicinal ointment.
CN201510031059.1A 2015-01-22 2015-01-22 Traditional Chinese medicine ointment for treating eczema and preparation method traditional Chinese medicine ointment Pending CN104587202A (en)

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