CN100551416C - 'Jinsong ' itching-relieving lotion - Google Patents
'Jinsong ' itching-relieving lotion Download PDFInfo
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- CN100551416C CN100551416C CNB200710202089XA CN200710202089A CN100551416C CN 100551416 C CN100551416 C CN 100551416C CN B200710202089X A CNB200710202089X A CN B200710202089XA CN 200710202089 A CN200710202089 A CN 200710202089A CN 100551416 C CN100551416 C CN 100551416C
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Abstract
Be used for adult female's vulvitis, damp-heat vaginal discharge, the 'Jinsong ' itching-relieving lotion of diseases such as pudendum and skin Pruritus.Be characterized in that Chinese medicine washing liquid of the present invention made by following raw materials in weight content: Herba Senecionis Scandentis 200-100g, Folium Eucalypti Robustae 200-100g, Cortex Dictamni 200-100g, Radix Scutellariae 70-30g, Flos Lonicerae 70-30g, Rhizoma Smilacis Glabrae 150-50g, Folium Pini 300-100g, Fructus Cnidii 150-100g, Radix Glycyrrhizae 70-30g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.Its advantage is that the nontoxic Chinese medicine of employing is that primary raw material is made, and except that the cleaning and protecting skin effect with common bath gel, also can prevent skin eczema, men and women's sexually transmitted disease (STD), and can be used for the bathroom facilities sterilization, the new external use health medicine that the prevention dermatopathy and venereal disease infects.
Description
Technical field
The present invention relates to a kind of adult female's of being used for vulvitis, damp-heat vaginal discharge, the 'Jinsong ' itching-relieving lotion of diseases such as pudendum and skin Pruritus.
Background technology
Along with country's opening, the enforcement of the policy of enlivening the domestic economy, domestic economy develops rapidly, the mobile personnel increases, suffering from dermopathic passenger increases by hotel bathroom facilities bedding propagation source of disease chance, particularly the coastal south temperature high humility is big, and men and women's sexually transmitted disease (STD) and dermopathic cross infection are even more serious.
Be used for the treatment of adult female's vulvitis at present, damp-heat vaginal discharge, the washing liquid of diseases such as pudendum and skin Pruritus has " FUFANG HUANGSONG XIYE " and " JIEERYIN XIYE " etc., these washing liquids have therapeutical effect preferably to above-mentioned inflammation, people continue many Chinese medicines are studied at present, to excavate more Chinese medicine washing liquid, treat above-mentioned inflammation, be mankind's service.
Summary of the invention
It is that house and out of town trip person study preparation except that the cleaning and protecting skin effect with common bath gel that purpose of the present invention just provides a kind of, also can prevent skin eczema, men and women's sexually transmitted disease (STD), and can be used for the bathroom facilities sterilization, the new external use health medicine that the prevention dermatopathy and venereal disease infects, and to adopt nontoxic Chinese herbal medicine be the 'Jinsong ' itching-relieving lotion of main material production.
Chinese medicine washing liquid of the present invention is made by following raw materials in weight content:
Herba Senecionis Scandentis 200-100g, Folium Eucalypti Robustae 200-100g, Cortex Dictamni 200-100g, Radix Scutellariae 70-30g, Flos Lonicerae 70-30g, Rhizoma Smilacis Glabrae 150-50g, Folium Pini 300-100g, Fructus Cnidii 150-100g, Radix Glycyrrhizae 70-30g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
A kind of production method of the present invention is: gets Folium Eucalypti Robustae and Folium Pini by weight, adds the water distillation, collect distillate 175g, and standby; Medicinal residues and all the other flavour of a drug decoct with water secondary, and 10 times of amounts were extracted 2 hours for the first time, and 4 times of amounts were extracted 1 hour for the second time, filter, and merging filtrate, vacuum concentration take out to about 400g, add 2 times of amounts of ethanol, stir evenly, and leave standstill 48 hours, filter; Filtrate 80.℃ reclaim ethanol to about 450g, standby; Get above-mentioned medicinal liquid, add the distillate that has collected the front, add water move to 1000ml, stir, mixing left standstill 12 hours, and fine straining promptly.
This prescription of prescription of the present invention medicine of respectively distinguishing the flavor of is Chinese herbal medicine used for a long time, and each medicine of distinguishing the flavor of all has definite curative effect, share and plays heat-clearing and toxic substances removing altogether, expelling wind and removing dampness, the merit of killing parasites for relieving itching.
Respectively distinguish the flavor of in the side relevant document record of medicine:
1, Folium Pini (Folium Pini)
1., " Guangxi book on Chinese herbal medicine a collection of selected materials ": " dispel the wind, dampness, promoting regeneration of the tissue and arresting bleeding, parasite killing, pain relieving.Cure mainly cold syndrome of the stomach pain, traumatic hemorrhage, rheumatic arthralgia, edema, chilblain, the carbuncle skin ulcer is festered, and burn and scald festers and does not close up for a long time, and articular sprain swells and ache, the skin tinea of itching.”
2., " Chinese medicine voluminous dictionary ": " dispel the wind except that dampness killing parasites for relieving itching.Can be used for treating the rheumatism flaccidity syndrome and arthralgia syndrome, traumatic injury, insomnia, edema, eczema, scabies.”
3., " book on Chinese herbal medicine converges and says ": " key medicine of the insane malignant boil of treatment tinea also for Folium Pini, curing rheumatism.The dry matter profit of property.Fry black kind curing rheumatism, stubborn dermatitis is wet mashed, does not soak and does, and freeze deep blue the deposited the eleventh month of the lunar calendar.Give birth to mash and make ball, can control big paralysis disease, or the severe and migratory arthralgia pain, or the beriberi flaccidity syndrome and arthralgia syndrome, or disease such as wind syndrome of head headache.”
4., " can cure mirror approximately ": " ward off pestilence gas.”
5., " the SHENGCAO property of medicine be equipped with want ": " kill magnetic, solid carbon dioxide, antipruritic, bury mouthful (closing the open sore part), wash chancre, control the magnetic scabies.”
6., " detailed outline ": " conference practice pain foot numbness is killed cadelle.”
7., " Japan hanako materia medica ": " moxibustion administration chilblain, rheumatism skin ulcer.”
8., " Waike Zhengzong, Orthodox Manual of External Diseases " record cooperates other medicine dispelling the wind and dampness pathogens stubborn dermatitis with Folium Pini, and removes the method for strong wind impetigo with Folium Pini." easy folk prescription " then put down in writing with Folium Pini and controlled the scrotum pruritus due to damp pathogen.
2, Folium Eucalypti Robustae
1., " Chinese medicine voluminous dictionary ": " heat-clearing and toxic substances removing.Cure cold, acute enteritis, dysentery, nephropyelitis, erysipelas, carbuncle is scalded, traumatic infection, ulcer of the lower limb is changed swollen property keratitis, the atrophic rhinitis.”
2., " south of the Five Ridges herbal ": " dispelling wind is analgesic, and is anticorrosion antipruritic.”
3., " Guangxi Chinese herbal medicine ": " heat-clearing and toxic substances removing, parasite killing convergence.Control diarrhoea, dysentery, flu is treated carbuncle furuncle and eczema.”
4., " record is treated deep pus infections with Folium Eucalypti Robustae in the Chinese herbal medicine handbook commonly used, traumatic infection, and neurodermatitis is scalded." Zhejiang medical herbs commonly used among the people " also is useful on the record of surgery disinfectant." the medical herbs handbook is washed affected part treatment ulcer of the lower limb with Folium eucalypti globueli (Eucalyptus globulus Labill.) soup.
3, Herba Senecionis Scandentis
1., " Guangxi book on Chinese herbal medicine a collection of selected materials ": " heat-clearing and toxic substances removing, removing the necrotic tissue makes new advances.Control influenza, icterohepatitis, parotitis, acute tonsillitis, acute dysentery, acute appendicitis, acute enteritis, gallbladder is assisted inflammation, and the pain skin ulcer is festered, eczema, impetigo is scalded, conjunctivitis.”
2., " Chinese medicine voluminous dictionary ": " heat-clearing and toxic substances removing, parasite killing make eye bright.Control various acute inflammatory diseases, the wind-fire acute conjunctivitis, corneal nebula, typhoid fever, bacillary dysentery, lobar pneumonia ... carbuncle is treated poison, dried exudative dermatitis skin ulcer, and erysipelas, eczema is scalded trichomonal vaginitis.”
3., " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " wash mange tinea skin ulcer, peeling skin wind heat.”
4., " Sichuan Chinese medicinal herbal ": " killing parasites for relieving itching is washed scrofula and all itchy skin eruptions (washout).”
5., " Jiangxi traditional herbal medicine " be loaded with Herba Senecionis Scandentis decoction being used as a lotion treatment skin sore, dried exudative dermatitis skin ulcer is person more with the passing of time, pruritus due to damp pathogen between toe, anus is itched, itching of vagina." Zhejiang medical herbs commonly used among the people " carries and to fry in shallow oil the soup washout with Herba Senecionis Scandentis and control skin of scrotum flowing water and very itch scabies, toxic swelling.
4, Cortex Dictamni
1., " Chinese medicine voluminous dictionary ": " dispel the wind dampness, heat clearing away, detoxifcation.Control the wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia.”
2., " property of medicine opinion ": " control all pyretic toxicity wind, aversion to wind, wind skin ulcer, scabies is red mashed etc. "
3., " book on Chinese herbal medicine is original ": " control all mange, aversion to wind, scabies, Fructus Myricae rubrae, all skin ulcer pyretic toxicity.”
4., " Shengji Zonglu ": " Cortex Dictamni looses and controls lung Tibetan wind heat, poison, attacks skin pruritus.”
5, Rhizoma Smilacis Glabrae
1., " Guangxi book on Chinese herbal medicine a collection of selected materials ": " detoxification and promoting urination, dispersing swelling and dissipating binds.Control that leptospirosis, diarrhoea, oedema due to nephritis, urinary tract infection, diabetes, tuberculous lymphadenitis, pain furuncle are swollen, rheumatic arthralgia, traumatic injury, the mashed head sore of children's.”
2., " Chinese medicine voluminous dictionary ": " detoxifcation, dehumidifying, sharp joint.Control syphilis, drench poison, muscles and bones spasm and pain, beriberi, carbuncle, scrofula.”
3., " Bencao Tujing ": " apply sore.”
4., " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control the five types of stranguria nebulousurine, double syphilitic sore, the erysipelas controlled.”
5., " book on Chinese herbal medicine just ": " treat carbuncle, sore throat removes whole body cold-damp malignant boil.”
6., " the SHENGCAO property of medicine is wanted fully ": " the sterilization skin ulcer is treated skin ulcer, and moxibustion juice applies it, and pot wine also can.”
7., " book on Chinese herbal medicine is new again ": " damp eliminating heat, relieving rigidity of muscles and joints.”
8., " Jiangxi medical herbs ": " parasite killing detoxifcation.”
9., " Jiangxi medical herbs " is with this medicine and tea root partner treatment stranguria with blood.Other flavor medicine treatment sore swollen toxins of the cooperation that " Zhejiang medical herbs commonly used among the people " used.Record in " the southern regions of the Yunnan Province book on Chinese herbal medicine ": control big skin infection redness, it is promptly indiscriminate to hope for success, and uses Rhizoma Smilacis Glabrae, is smalls, and good vinegar is transferred and applied.Two to three liang of Rhizoma Smilacis Glabraes of " Jiangxi medical herbs " record, decocting is worked as tea-drinking: treatment dermatitis.
6, Fructus Cnidii
1., " Guangxi book on Chinese herbal medicine a collection of selected materials ": " killing parasites for relieving itching, warming the kidney to invigorate YANG.Control vulval eczema, trichomonal vaginitis, cervical erosion, skin scabies, infantile eczema, antiperspirant suitcase rash, sexual impotence.”
2., " Chinese medicine voluminous dictionary ": " parasite killing is controlled the scrotum rash for warming the kidney to activate YANG, dispeiling pathogenic wind and removing dampness, women's leukorrhagia pudendal pruritus ... scabies eczema.”
3., " herbal classic ": " swelling and ache man's impotence, pruritus due to damp pathogen in housewife people's the moon ... "
4., " property of medicine opinion ": " main strong wind itching over the body is fried in shallow oil being recovered that soup controls.”
5., " giving birth to the herbal property of medicine wants fully ": " it is antipruritic to apply skin ulcer.”
6., " be on the point of collection letter side, lake " and carry and fry in shallow oil soup washout married woman pudendal pruritus with Alumen." a collection of selected materials of Chinese herbal medicine new therapy that combines both Chinese and Western medical practices data " (Inner Mongol): Fructus Cnidii decocting lavation vagina is controlled trichomonal vaginitis." medical herbs handbook (Jiangxi): the Fructus Cnidii list is used or compatibility treatment eczema scrotum, allergic dermatitis, tinea manus and pedis.
7, Flos Lonicerae
1., " Guangxi book on Chinese herbal medicine a collection of selected materials ": " heat-clearing and toxic substances removing.The wind heat that cures cold, dysentery, enteritis, tonsillitis, acute conjunctivitis, acute appendicitis is spitted blood, spitting of blood, metrorrhagia is had blood in stool, mastitis, trauma infection contamination, innominate toxic swelling, skin infection festers.”
2., " Chinese medicine voluminous dictionary ": " heat-clearing and toxic substances removing.Control the damp disease heating, carbuncle and ulcer, toxic swelling, scrofula.”
3., " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " heat clearing away.Separate all skin ulcers, carbuncle cellulitis carbuncle on the back, red stream scrofula "
4., essentials of Matea Medica: " nourish blood and quench the thirst.Control scabies.”
5., " the SHENGCAO property of medicine is wanted fully ": " can the eliminating carbuncle cellulitis treat poison ... remove the peel the skin heat in blood.”
6., " hall of accumulating virtue is through proved recipe ": " apply with slag with the Flos Lonicerae decoction, control all toxic swellings "
7., " Medicine Comprehended ": " fry in shallow oil the water clothes altogether with Radix Glycyrrhizae and control external carbuncle in all.”
8., " surgery ten methods ": " match to be decocted in water for oral dose with Radix Glycyrrhizae, Rhizoma Smilacis Glabrae, Black Semen glycines sojae and control syphilis of the bone.”
8, Radix Scutellariae
1., " Chinese medicine voluminous dictionary ": " removing the relative excess fire.Except that damp and hot, hemostasis, antiabortive, control the high fever excessive thirst ... carbuncle is treated skin ulcer.”
2., " Japan hanako materia medica ": " therapeutic method to keep the adverse QI flowing downwards, the main day hot disease of row treated skin ulcer, evacuation of pus.”
3., " strange card odd-prescription ": " Radix Scutellariae (parched with wine) 2 money, for not, the wine clothes are controlled post-moxibustion sore blood and are gone out.”
4., " Mei Shi collection proved recipe ": " erysipelas of controlling of applying is transferred at pestle Radix Scutellariae end, water.”
9, Radix Glycyrrhizae
1., " Chinese medicine voluminous dictionary ": ", detoxify coordinating the actions of various ingredients in a prescription with middle emergency, lung moistening.Give birth to controlling ulcer sores ... "
2., Materia Medica of Decoction: " skin ulcer cellulitis of five etc. disappears.”
3., " herbal classic ": " main incised wound is swollen, detoxifcation.”
4., " health preserving must with side ": " the Radix Glycyrrhizae decoction being used as a lotion be controlled uncontrolled urination and is itched.”
5., " strange card odd-prescription ": " Radix Glycyrrhizae is fried in shallow oil close being coated with and controls the bright skin ulcer of soup fire.”
The side separates:
Theory of Chinese medical science is thought: damp-heat vaginal discharge, vulvitis, nonspecific vaginitis and skin pruritus etc. all cause a disease because of damp and hot ailment said due to cold or exposure virus.It is rule of treatment that treatment is worked as with heat-clearing and toxic substances removing, expelling wind and removing dampness.And we are made up of the medicine with heat-clearing and toxic substances removing, expelling wind and removing dampness, killing parasites for relieving itching effect just.
With heat-clearing and toxic substances removing, expelling wind and removing dampness, the killing parasites for relieving itching of Herba Senecionis Scandentis, Folium Eucalypti Robustae, Cortex Dictamni, be the monarch drug in the side in the side.
With heat clearing and damp drying, the detoxifcation of Radix Scutellariae, Flos Lonicerae, Rhizoma Smilacis Glabrae, the effect of strengthening monarch drug heat-clearing and toxic substances removing, dampness is arranged, so the ministerial drug in the side of being.
Folium Pini, Fructus Cnidii are product warm in nature, and dispeiling pathogenic wind and removing dampness, detoxifcation parasite killing, antipruritic effect are arranged, and are the adjuvant drug in the side.
The Radix Glycyrrhizae sweet in the mouth is flat, the merit of heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription is arranged, so the messenger drug in the side of being.
All medicines are usefulness entirely, becomes the agent of heat-clearing and toxic substances removing, expelling wind and removing dampness, killing parasites for relieving itching altogether.
Herba Senecionis Scandentis in the side, bitter in the mouth is cool in nature, and the effect of heat-clearing and toxic substances removing, expelling wind and removing dampness is arranged.Cure mainly diseases such as the carbuncle furuncle is swollen, dried scabies humida tinea, eczema scrotum.Folium Eucalypti Robustae, bitter in the mouth, hot puckery, gas perfume (or spice) is cool in nature.The merit that heat-clearing and toxic substances removing, parasite killing convergence are arranged.Cure mainly that the carbuncle furuncle is swollen, eczema etc.Cortex Dictamni, bitter in the mouth is cold in nature, and heat-clearing and toxic substances removing, expelling wind and removing dampness, antipruritic merit are arranged.Cure mainly diseases such as rubella due to the wind heat noxious dampness, eczema, impetigo, scabies.More than three medicines share, the merit of heat-clearing and toxic substances removing, expelling wind and removing dampness, killing parasites for relieving itching is arranged, so the monarch drug in the side of being.
Radix Scutellariae in the side, bitter in the mouth is cold in nature, and the merit of heat clearing and damp drying is arranged.Flos Lonicerae, sweet in the mouth is cold in nature, and the function heat-clearing and toxic substances removing is the key medicine of treatment carbuncle pyogenic infections from tumour or sore.Rhizoma Smilacis Glabrae, slightly sweet flavor, property is flat, function dehumidifying, heat-clearing and toxic substances removing.Cure mainly diseases such as syphilis, stranguria with turbid discharge, carbuncle, skin ulcer tinea.Rhizoma Smilacis Glabrae is also for treating the key medicine of syphilis.Compendium of Material Medica contained it " search wind detoxifcation soup ", treatment syphilitic skin lesion (syphilis), though the depth, so be principal agent with this product.Modern clinically join Flos Lonicerae, Radix Glycyrrhizae etc. with Rhizoma Smilacis Glabrae, the existing disease syphilis of treatment, latent syphilis all have certain effect.The treatment sore swollen toxin can be joined Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci etc.Radix Scutellariae, Flos Lonicerae, Rhizoma Smilacis Glabrae three medicines share, and so have heat clearing and damp drying, detoxifcation and can strengthen the effect of monarch drug the ministerial drug in the side of being.
Folium Pini in the side, bitter and puckery flavor, property is wet, have dispel the wind, invigorate blood circulation, detoxifcation, antipruritic merit, external controls that the carbuncle furuncle is swollen, eczema etc.Fructus Cnidii, the bitter in the mouth suffering, warm in nature.External has the merit of removing dampness and killing parasites.Cure mainly diseases such as scabies, stubborn dermatitis, eczema.Folium Pini, Fructus Cnidii share, have dispeiling pathogenic wind and removing dampness, detoxifcation, parasite killing, antipruritic it; Effect is to be the adjuvant drug in the side.
Radix Glycyrrhizae, sweet in the mouth is flat, the merit of heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription is arranged, so the messenger drug in the side of being.
More than all medicines share, become the agent of heat-clearing and toxic substances removing, expelling wind and removing dampness, killing parasites for relieving itching altogether and cure mainly above-mentioned all diseases.
Advantage of the present invention is that the nontoxic Chinese medicine of employing is that primary raw material is made, and except that the cleaning and protecting skin effect with common bath gel, also can prevent skin eczema, men and women's sexually transmitted disease (STD), and can be used for the bathroom facilities sterilization, the new external use health medicine that the prevention dermatopathy and venereal disease infects.
The present invention is through No.1 Hospital Attached to Guangxi Medical Univ., Guangxi institute of internal medicine, No. 1 People's Hospital of Nanning adopts at random, the method of contrast is to 115 routine leukorrhagia, the pruritus caused by wind pathogen patient has carried out clinical verification, (establishing matched group 56 examples in addition), the result proves that 'Jinsong ' itching-relieving lotion of the present invention truly has heat-clearing and toxic substances removing, expelling wind and removing dampness, the effect of killing parasites for relieving itching, differential diagnosis in tcm belongs to the vulvitis of damp-heat leukorrhagia, nonspecific vaginitis patient and differential diagnosis in tcm belong to wind heat blood-heat type pruritus caused by wind pathogen disease patient therapeutical effect, 115 routine total effective rates this 86.1%, this product safety is reliable, and viewing duration is not found obvious adverse reaction and toxic and side effects.
Through Hospital No.1 Attached to Zhongsha Medical Science Univ.'s department of dermatologry to the sexually transmitted disease (STD) of infectious nephropathy and common genital area totally 85 examples treat, total effective rate is 83.4%, the proof antipruritic effect is remarkable, rapid-action, has certain bacteriostasis, infectious skin disease and genitals smelting leaf site sexually transmitted disease (STD) there is certain therapeutical effect, can make the shortening course of treatment of its conventional therapy, the symptom and sign morbidity improves fast, helping the cloudy commentaries on classics of pathogen, is infectious skin disease and the optional auxiliary therapeutic agent of reproduction position sexually transmitted disease (STD).
Through prevention and treatment of venereal diseases center, Guangzhou to gonococcal urethritis (vaginitis and nongonococcal urethritis) totally 73 examples treat, proof has antiinflammatory, removes scorching, itching relieving effect, and shortened the course of treatment, easy to use, non-evident effect is obtained satisfied curative effect, under using with a kind of condition for the treatment of gonorrhea and non-gonorrhea medicine contemporaneity, add and use 'Jinsong ' itching-relieving lotion of the present invention, cure rate 97.6% is higher than the matched group (70%) that does not add with 'Jinsong ' itching-relieving lotion altogether.
Through the Wuhan Chinese ﹠ Westen Medicine Hospital to eczema, skin class itching skin disease totally 103 examples treat its common cure rate 28.2%, obvious effective rate 32%, effective percentage 23.3%, total effective rate is 83.5%, and medication in half an hour itching-relieving action takes place promptly, does not see other any toxic and side effects.
Department of obstetrics and gynecology are treated 120 routine patients through chaste tree Shashi, Hubei Province central hospital, proof has antibacterial, antiinflammatory, effect such as antipruritic, antipruritic effect is remarkable, rapid-action, even the invalid patient of some other medicine for external use also had antipruritic preferably, anti-inflammatory effect, drug effect often began to occur after medication in several minutes, particularly the agnogenio person of the long-term pruritus of pudendum, even some patient's skin of vulva thickens, and antipruritic effect 100% after the medication; Have the quick-acting bactericidal actions of wide spectrum, especially for vulvitis, pudendum, colpitis that nonspecific vaginitis, infusorian, colpitis mycotica or infection such as gonococcus, chlamydia cause, with the dilute liquid medicine washout, vaginadouche and outer spray combine, local symptom can disappear in 24-48 hour, leucorrhea can reduce rapidly, and the vulvar erosions face heals rapidly, and pruritus vulvae disappears, 1-2 further consultation after week, it is negative to look into bacterium.
The specific embodiment
This parasol pine itching-relieving lotion is made by following raw materials in weight content:
Herba Senecionis Scandentis 200-100g, Folium Eucalypti Robustae 200-100g, Cortex Dictamni 200-100g, Radix Scutellariae 70-30g, Flos Lonicerae 70-30g, Rhizoma Smilacis Glabrae 150-50g, Folium Pini 300-100g, Fructus Cnidii 150-100g, Radix Glycyrrhizae 70-30g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
Following table embodiment is the component and the content of the required Chinese medicine extract of the every 1000ml preparation of the present invention:
| The name of an article | Herba Senecionis Scandentis | Cortex Dictamni | Folium Eucalypti Robustae | Flos Lonicerae | Radix Scutellariae | Rhizoma Smilacis Glabrae | Fructus Cnidii | Folium Pini | Radix Glycyrrhizae |
| Prescription one (g) | 200 | 150 | 200 | 70 | 30 | 50 | 150 | 100 | 50 |
| Prescription two (g) | 100 | 200 | 100 | 50 | 30 | 150 | 150 | 150 | 70 |
| Prescription three (g) | 150 | 100 | 100 | 30 | 70 | 100 | 100 | 300 | 50 |
| Prescription four (g) | 150 | 200 | 150 | 70 | 50 | 150 | 100 | 100 | 30 |
| Prescription five (g) | 200 | 100 | 100 | 50 | 50 | 150 | 100 | 200 | 50 |
| Prescription six (g) | 100 | 200 | 150 | 30 | 50 | 100 | 150 | 150 | 70 |
| Prescription seven (g) | 150 | 100 | 200 | 70 | 30 | 50 | 100 | 250 | 50 |
| Prescription eight (g) | 100 | 150 | 150 | 50 | 50 | 100 | 100 | 250 | 50 |
| Prescription nine (g) | 150 | 150 | 100 | 30 | 70 | 150 | 100 | 200 | 50 |
| Prescription ten (g) | 150 | 150 | 150 | 30 | 50 | 150 | 150 | 100 | 70 |
Most preferred embodiment is:
Herba Senecionis Scandentis 150g, Folium Eucalypti Robustae 150g, Cortex Dictamni 150g, Radix Scutellariae 50g, Flos Lonicerae 50g, Rhizoma Smilacis Glabrae 100g, Folium Pini 200g, Fructus Cnidii 100g, Radix Glycyrrhizae 50g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
In the above-described embodiments, preparation method of the present invention is, by arbitrary embodiment of last table or most preferred embodiment preparation raw material, gets Folium Eucalypti Robustae and Folium Pini by weight, adds the water distillation, collects distillate 175g, and is standby; Medicinal residues and all the other flavour of a drug decoct with water secondary, and 10 times of amounts were extracted 2 hours for the first time, and 4 times of amounts were extracted 1 hour for the second time, filter, and merging filtrate, vacuum concentration take out to about 400g, add 2 times of amounts of ethanol, stir evenly, and leave standstill 48 hours, filter; Filtrate is reclaimed ethanol to about 450g for 80 ℃, and is standby; Get above-mentioned medicinal liquid, add the distillate that has collected the front, add water move to 1000ml, stir, mixing left standstill 12 hours, and fine straining promptly.
The acute toxicity test report of 'Jinsong ' itching-relieving lotion of the present invention
(sample)
'Jinsong ' itching-relieving lotion contains alcohol 26%, and every ml contains crude drug 1g.Clinical plan is coated with or is sprayed on the affected part for 1-2ml/ time with this product, every day 2 times.Test sample is 10 times of concentrated solutions of this product, contains alcohol 20%.
(animal)
Cavia porcellus: regular grade, ♀ ♂ dual-purpose, body weight 250-500g purchases in this city country fair, and animal feeding is fed mixed fodder and greenfeed in the automated cleaning cage.18 ± 2 ℃ of experiment room temperatures, relative humidity 60 ± 5% adapts to this chamber condition and supplies examination after one week.
(method and result)
1, Cavia porcellus intact skin acute toxicity test
Get 20 of Cavia porcelluss, ♀ ♂ half and half, with 1ml/kg/ dispensing of test sample, the ♀ Cavia porcellus splashes into intravaginal and is applied to its surrounding skin, and the ♂ Cavia porcellus is applied to penis and surrounding skin thereof, all is administered four times in 12 hours.Observe the situation such as outward appearance, behavior, appetite, drainage, body weight, death of Cavia porcellus in 7 days.After the administration 7 days as a result, the outward appearance of Cavia porcellus, behavior, appetite, drain, show no obvious abnormalities, the no phenomena of mortality, but body weight and on average alleviate 4.8% after 7 days.
2, Cavia porcellus damaged skin acute toxicity test
Get 8 of Cavia porcelluss, ♀ ♂ half and half is divided into 2 groups at random, the cropping respectively of both sides, every Mus back, the about 4 * 5cm of area
2, after the sterilization of 2% iodine tincture, become " T " shape with blade incised wound skin, be about 3cm, reach subcutaneous tissue deeply.Two groups all are coated with respectively with test sample and deionized water by 1ml/ time, every day 1 time, continuous 7 days, general toxic reaction and the local wound healing state of Cavia porcellus during the observation administration.The outward appearance of all Cavia porcelluss, behavior, appetite, drainage as a result shows no obvious abnormalities, and the no phenomena of mortality, local wound are swollen, the downright bad phenomenon of water breakthrough not, incrustation in the 3rd day, and all decrustations are not seen significant difference for two groups in 11 days.
(conclusion)
This product there is no obvious acute toxic reaction through Cavia porcellus intravaginal administration, external genitalia and surrounding skin coating thereof, damaged skin coating, and the Cavia porcellus weight average alleviates 4.8%, and maximum tolerated dose is greater than 40ml/kg (be equivalent to clinical plan consumption 500 times).Should be safe by intending consumption in clinical practice.
Model case:
Case one:
Poplar, man, 30 years old, Jinan, Nanning City road general merchandise market self-employed entrepreneurs.Urethra flows out dense sexual secretion, glans penis flushing, swelling, rotten to the corn two days, chemical examination gonococcus positive when on March 9th, 1 went to a doctor, examine and be acute gonorrhea and balanitis, give one bottle of 'Jinsong ' itching-relieving lotion, advise its dilution back to soak or wet gesture part, after four days, reddened and swollen glans penis disappears substantially, and rotten to the corn reduction of area is little, advises it to continue medication, came further consultation March 17, erythra disappears fully, check gonococcus ball feminine gender, patient satisfaction.
Case two:
The week so-and-so, the man, 32 years old, the Nanning City built two work area workmans, once suffered from gonorrhea before 3 years.Coronary sulcus pimpling before half a year, once examined in this city hospital and be " condyloma acuminatum ", burnt with snack made with traditional Chinese medicines, local rotten to the corn, the coronary sulcus edema, a little sepage was gone to a doctor on March 19th, 1, intended condyloma acuminatum and infected, doing the chlamydia inspection is positive, give the 'Jinsong ' itching-relieving lotion dilution and soak, further consultation on March 27, erythra recovery from illness.April 27, the duplicate chlamydia was negative.
Case three:
Peng so-and-so, the woman, 46 years old, the city proper and areas just outside its gates, Ningming County workman, lover suffers from gonorrhea the year before, its infected (looking into the gonococcus positive) be dysurea often, pruritus vulvae, the time redness, erosion arranged.Go to a doctor on March 31st, 1, the pudendum redness of regarding sb. as an outsider is looked into the gonococcus feminine gender, gives 2 bottles of soaks of 'Jinsong ' itching-relieving lotion or presses spray, comes further consultation on April 15, and pudendum is red and swollen to disappear, and pruritus alleviates, patient satisfaction.
Case four:
Thunder so-and-so, man, 29 years old, southern machine workman, suffered from gonorrhea before half a year, rotten to the corn three months of glans penis is instead done, repeatedly repeatedly at the city hospital therapy, effect is undesirable, goes to a doctor on March 12nd, 1, and (laboratory personnel's balanitis has a holiday, do not do chemical examination), give 1 bottle of 'Jinsong ' itching-relieving lotion, soak or immersion, further consultation on March 26, rotten to the corn reduction of area is little by 1/2, gives one bottle of 'Jinsong ' itching-relieving lotion soak again, further consultation on April 25, rotten to the corn face recovery from illness, the patient is very grateful.
Case five:
Hu, the women, 40 years old, pruritus vulvae over 2 months, profuse leukorrhea, yellow skin, matter is sticky, and is smelly dirty, red tongue yellow and greasy fur, vagina cleanness degree.The vaginal secretion object lens are checked down: leukocyte (+++), pyocyte (+).Western medicine diagnose: nonspecific vaginitis.Tcm diagnosis: leukorrhagia (damp-heat type).Give the 'Jinsong ' itching-relieving lotion treatment.Played symptom on the 3rd day and all disappear, gynecological's check in the 7th day, vagina cleanness degree, vaginal secretions microscopy leukocyte and pyocyte are all turned out cloudy.
Case six:
Thunder, the male, 38 years old, skin pruritus January surplus, obvious with abdominal part and strand medial part, have less and irregular scratch is examined skin pruritus.Give the 'Jinsong ' itching-relieving lotion treatment.Played pruritus on the 3rd day and alleviate, pruritus disappeared in the 7th day, and scratch disappears.
Claims (10)
1. 'Jinsong ' itching-relieving lotion, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 200-100g, Folium Eucalypti Robustae 200-100g, Cortex Dictamni 200-100g, Radix Scutellariae 70-30g, Flos Lonicerae 70-30g, Rhizoma Smilacis Glabrae 150-50g, Folium Pini 300-100g, Fructus Cnidii 150-100g, Radix Glycyrrhizae 70-30g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
2. 'Jinsong ' itching-relieving lotion according to claim 1, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 150g, Folium Eucalypti Robustae 150g, Cortex Dictamni 150g, Radix Scutellariae 50g, Flos Lonicerae 50g, Rhizoma Smilacis Glabrae 100g, Folium Pini 200g, Fructus Cnidii 100g, Radix Glycyrrhizae 50g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
3. 'Jinsong ' itching-relieving lotion according to claim 1, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 200g, Folium Eucalypti Robustae 200g, Cortex Dictamni 150g, Radix Scutellariae 50g, Flos Lonicerae 70g, Rhizoma Smilacis Glabrae 50g, Folium Pini 100g, Fructus Cnidii 150g, Radix Glycyrrhizae 50g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
4. 'Jinsong ' itching-relieving lotion according to claim 1, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 100g, Folium Eucalypti Robustae 100g, Cortex Dictamni 200g, Radix Scutellariae 30g, Flos Lonicerae 50g, Rhizoma Smilacis Glabrae 150g, Folium Pini 150g, Fructus Cnidii 150g, Radix Glycyrrhizae 70g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
5. 'Jinsong ' itching-relieving lotion according to claim 1, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 150g, Folium Eucalypti Robustae 100g, Cortex Dictamni 100g, Radix Scutellariae 70g, Flos Lonicerae 30g, Rhizoma Smilacis Glabrae 100g, Folium Pini 300g, Fructus Cnidii 100g, Radix Glycyrrhizae 50g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
6. 'Jinsong ' itching-relieving lotion according to claim 1, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 150g, Folium Eucalypti Robustae 150g, Cortex Dictamni 200g, Radix Scutellariae 50g, Flos Lonicerae 70g, Rhizoma Smilacis Glabrae 150g, Folium Pini 100g, Fructus Cnidii 100g, Radix Glycyrrhizae 30g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
7. 'Jinsong ' itching-relieving lotion according to claim 1, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 200g, Folium Eucalypti Robustae 100g, Cortex Dictamni 100g, Radix Scutellariae 50g, Flos Lonicerae 50g, Rhizoma Smilacis Glabrae 150g, Folium Pini 200g, Fructus Cnidii 100g, Radix Glycyrrhizae 50g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
8. 'Jinsong ' itching-relieving lotion according to claim 1, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 100g, Folium Eucalypti Robustae 150g, Cortex Dictamni 200g, Radix Scutellariae 50g, Flos Lonicerae 30g, Rhizoma Smilacis Glabrae 100g, Folium Pini 150g, Fructus Cnidii 150g, Radix Glycyrrhizae 70g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
9. 'Jinsong ' itching-relieving lotion according to claim 1, it is characterized in that it is made by following raw materials in weight content: Herba Senecionis Scandentis 150g, Folium Eucalypti Robustae 200g, Cortex Dictamni 100g, Radix Scutellariae 30g, Flos Lonicerae 70g, Rhizoma Smilacis Glabrae 50g, Folium Pini 250g, Fructus Cnidii 100g, Radix Glycyrrhizae 50g, adding distil water, ethanol are an amount of, make the 1000ml medicinal liquid altogether.
10. according to the preparation method of claim 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 described 'Jinsong ' itching-relieving lotions, it is characterized in that getting Folium Eucalypti Robustae and Folium Pini by weight, add the water distillation, collect distillate 175g, standby; Medicinal residues and all the other flavour of a drug decoct with water secondary, and 10 times of amounts were extracted 2 hours for the first time, and 4 times of amounts were extracted 1 hour for the second time, filter, and merging filtrate, vacuum concentration take out to about 400g, add 2 times of amounts of ethanol, stir evenly, and leave standstill 48 hours, filter; Filtrate is reclaimed ethanol to about 450g for 80 ℃, and is standby; Get above-mentioned medicinal liquid, add the distillate that has collected the front, add water move to 1000ml, stir, mixing left standstill 12 hours, and fine straining promptly.
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| CN101366898B (en) * | 2008-09-27 | 2011-04-27 | 浙江巨都药业集团有限公司 | Gynopathy treating traditional Chinese medicine composition and method of preparing the same |
| CN101849983B (en) * | 2010-06-10 | 2011-08-10 | 吴启明 | Medicament for treating eczema |
| CN102302715B (en) * | 2011-09-24 | 2012-12-12 | 徐宝兰 | External medicine for perineal incision and preparation method thereof |
| CN103462740B (en) * | 2013-09-25 | 2015-06-10 | 桂林恒保健康用品有限公司 | Condom for treating cervical erosion |
| CN103637973A (en) * | 2013-12-02 | 2014-03-19 | 太仓市伟基生物科技有限公司 | Skin-protecting and itch-relieving bath cream |
| CN104688823B (en) * | 2013-12-10 | 2017-09-29 | 广西壮族自治区花红药业股份有限公司 | Antipruritic Chinese medicine composition of a kind of anti-inflammation and preparation method thereof |
| CN104474076A (en) * | 2014-12-06 | 2015-04-01 | 重庆市中医院 | Traditional Chinese medicine composition for treating eczema |
| CN105560498B (en) * | 2016-02-05 | 2019-05-03 | 株洲千金药业股份有限公司 | It is a kind of with antibacterial, disinfection medical fluid and its application |
| CN105749084B (en) * | 2016-02-05 | 2019-05-03 | 株洲千金药业股份有限公司 | It is a kind of with antibacterial, disinfection medical fluid and its application |
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