CN104587033A - Nano-silver rhinitis cream - Google Patents

Nano-silver rhinitis cream Download PDF

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Publication number
CN104587033A
CN104587033A CN201410830992.0A CN201410830992A CN104587033A CN 104587033 A CN104587033 A CN 104587033A CN 201410830992 A CN201410830992 A CN 201410830992A CN 104587033 A CN104587033 A CN 104587033A
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parts
rhinitis
radix
nanometer silver
silver
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CN201410830992.0A
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CN104587033B (en
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徐爱玲
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Wuhan Ciningtang Medical Technology Co Ltd
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Wuhan Ciningtang Medical Technology Co Ltd
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Abstract

The invention belongs to the technical field of treatment for rhinitis, and specifically relates to a nano-silver rhinitis cream. The nano-silver rhinitis cream comprises the following components in parts by weight: 10-20 parts of radix gentianae, 10-25 parts of fingered citron, 10-20 parts of mint, 10-20 parts of coptis chinensis, 10-20 parts of wild chrysanthemum flower, 10-20 parts of pearl, 10-20 parts of honeysuckle, 10-20 parts of salvia miltiorrhiza, 10-20 parts of beautiful sweetgum fruit, 10-20 parts of cortex dictamni, 10-20 parts of houttuynia cordata, 10-20 parts of rheum officinale, 10-20 parts of asarum, 10-20 parts of radix angelicae, 10-20 parts of liquorice, 10-20 parts of violet magnolia, 1-10 parts of camphor, 10-20 parts of radix scrophulariae, 10-20 parts of white paeony root, 10-80 parts of nano-silver and 1-10 parts of borneol. The nano-silver rhinitis cream disclosed by the invention is searched on the basis of a-hundred-year ancestral secret prescription, is prepared from pure traditional Chinese medicine components, and is scientific and reasonable, free from toxic and side effects, quick in curative effect, good in curative effect, stable in efficacy, remarkable in treatment effect on allergic rhinitis, acute or chronic rhinitis, atrophic rhinitis, nasosinusitis, nasal polyp and acute or chronic nasosinusitis, capable of realizing radical cure at one time, and free from recurrence.

Description

A kind of nanometer silver rhinitis ointment
Technical field
The invention belongs to the treatment technology field of rhinitis, be specifically related to a kind of nanometer silver rhinitis ointment.
Background technology.
Silver can kill the microorganisms such as antibacterial, virus, fungus, but harmless to human normal cell, has multiple special efficacy very widely.Silver ion all has good therapeutic effect for treatment gastritis, malaria, parasitic infection, psoriasis, ear,nose & throat, ophthalmology, department of stomatology infection, yeast infection, and it can take orally also can external.It can control the antibacterial bacterial strain of obstinate drug resistance effectively, the drug resistance flora of stubbornness is comprised to the existence of antibacterial known today and extracellular virus, and silver has the effect well killed or suppress, and can not produce any Drug resistance.Even silver ion complexes can extend the life of full-blown AIDS patient, has significant resistance to the virus in its body, antibacterial, and it can reduce some appeal that may cause the virus of acquired immune deficiency syndrome (AIDS), effectively prevents AIDS.
Silver after nanotechnology is broad spectrum high-effect antibacterial especially, there is antibacterial effect more lasting more outstanding, to comprise antibacterial, fungus, infusorian, mycoplasma multiple noxious bacteria have and well suppress or killing action, have equal killing power to Resistant strain flora, antibiotic rate reaches more than 99.9%.Money base serial nano antibacterial to the pathogenic bacteria killing rate of escherichia coli, staphylococcus aureus these two kinds serious threat human healths in life up to 99.99%.
Nanoscale science and technology is cross-centennial new disciplines, is the core high-end technology of 21 century.It is the hot spot technology that countries in the world scientific circles and engineering technological are extremely paid close attention to, the development of nanotechnology has caused the revolution far away of a field depth of drug world, kink characteristics and the surprising efficacy of Nano medication product property cause gazing at of common people, the effective ingredient using nanotechnology manufacture particle diameter to be less than 100nm acts on former medicine and the compound preparation of effective site, not only can improve the bioavailability of medicine, the toxic and side effects of effective reduction Chinese medicine, strengthens clinical efficacy.Because nanotechnology is to the effect of medicine Ultrafine, its large specific surface area increases agents area and is exposed to specific surface area in medium, facilitate the dissolubility of medicine, because its particle diameter is very little, increase medicine Germ distribution in vivo, substantially increase drug absorption and utilization rate, facilitate giving full play to of curative effect of medication, thus obtain surprising, beyond thought fancy effect.
But the Chinese medicine of current treatment rhinitis, mainly make confection with various Chinese medicine and used again.Drug effect and treatment cycle are all more general.
Summary of the invention
For solving the deficiencies in the prior art, the object of this invention is to provide a kind of nanometer silver rhinitis ointment.
A kind of nanometer silver rhinitis ointment, comprise each component of following parts by weight: Radix Gentianae 10 ~ 20 parts, Fructus Citri Sarcodactylis 10 ~ 25 parts, Herba Menthae 10 ~ 20 parts, Rhizoma Coptidis 10 ~ 20 parts, Flos Chrysanthemi Indici 10 ~ 20 parts, Margarita 10 ~ 20 parts, Flos Lonicerae 10 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 20 parts, Fructus Liquidambaris 10 ~ 20 parts, Cortex Dictamni 10 ~ 20 parts, Herba Houttuyniae 10 ~ 20 parts, Radix Et Rhizoma Rhei 10 ~ 20 parts, Herba Asari 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts, 10 ~ 20 parts, Radix Glycyrrhizae, Flos Magnoliae 10 ~ 20 parts, Camphora 1 ~ 10 part, Radix Scrophulariae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, nanometer silver 10 ~ 80 parts, Borneolum Syntheticum 1 ~ 10.
Preferably, nanometer silver is 20 ~ 40 parts, or 25 ~ 60 parts, or 50 ~ 80 parts.
Preferably, 1 ~ 10 part, Moschus is also comprised.
Preferably, Folium Perillae 10 ~ 20 parts is also comprised.
Preferably, also comprise 40 ~ 100 parts, vaseline, or 40 ~ 100 parts, Cera Flava.
Radix Gentianae: eliminating pathogen in the liver gallbladder excess-fire, except damp-heat in lower-JIAO.Treating the liver is through intenseness of heat, and infantile convulsion is manic, and headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, scrotum swells and ache, pudendum pruritus due to damp pathogen.For damp and hot yellow cellulitis, swelling of the vulva pudendal pruritus, leukorrhagia, eczema pruritus, deafness, hypochondriac pain, bitter taste, convulsion with spasms.
Flos Lonicerae: cure mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, has stronger restraint to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc.
Fructus Liquidambaris: dispelling wind and removing obstruction in the collateral, diuretic dehumidifies.Control limbs arthralgia pain, contracture of the limbs, stomachache, edema, distension, amenorrhea, breast is few, carbuncle, anal fistula, scabies, eczema.
Herba Asari: dispel the wind, cold expelling, row water, has one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.
Flos Magnoliae: dispel the wind, sensible.Control headache, nasal sinusitis, have a stuffy nose obstructed, toothache.
The Radix Angelicae Dahuricae: dispel the wind, dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Cortex Dictamni: dispel the wind, dampness, heat clearing away, removing toxic substances.Control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.
Radix Scrophulariae: warm febrile disease and nutrient blood; Fever of the body; Excessive thirst; Crimson tongue; Send out speckle; Hectic fever due to YIN-deficiency chronic cough; Fidgets due to deficiency is awake not; Constipation is hindered in Tianjin; Order is puckery dim-sighted; Throat larynx swells and ache; Scrofula sucutaneous nodule; Skin sore.
The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Nanometer silver rhinitis ointment provided by the present invention, has stronger bacteriostasis to nasal cavity antibacterial, fungus, effectively can remove retaining and propagating of nasal cavity pathogenic bacteria, makes nasal cavity keep happy sensible, clean health, nontoxic to nasal membrane, non-stimulated.Frequent use can recover the normal function of nasal cavity.It develops based on century-old secret prescription handed down in the family from generation to generation, pure Chinese medicinal components, scientific and reasonable, has no side effect, curative effect is fast, good effect, efficacy stability, evident in efficacy to allergic rhinitis, acute and chronic rhinitis, atrophic rhinitis, sinusitis, nasal polyp, acute and chronic nasal sinusitis, disposablely can effect a radical cure, do not recur.
Detailed description of the invention
Be described principle of the present invention and feature below, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1
A kind of nanometer silver rhinitis ointment, comprise each component of following parts by weight: Radix Gentianae 11 parts, Fructus Citri Sarcodactylis 18 parts, Herba Menthae 14 parts, Rhizoma Coptidis 10 parts, Flos Chrysanthemi Indici 20 parts, Margarita 15 parts, Flos Lonicerae 13 parts, Radix Salviae Miltiorrhizae 17 parts, Fructus Liquidambaris 16 parts, Cortex Dictamni 10 parts, Herba Houttuyniae 17 parts, Radix Et Rhizoma Rhei 13 parts, Herba Asari 11 parts, the Radix Angelicae Dahuricae 19 parts, 16 parts, Radix Glycyrrhizae, Flos Magnoliae 10 parts, Camphora 8 parts, Radix Scrophulariae 15 parts, the Radix Paeoniae Alba 12 parts, nanometer silver 20 parts, Borneolum Syntheticum 2 parts, 9 parts, Moschus, Folium Perillae 15 parts, 40 parts, vaseline.
Will Homogeneous phase mixing after each component grinding above, the medicine to paste, both.
Embodiment 2
A kind of nanometer silver rhinitis ointment, comprise each component of following parts by weight: Radix Gentianae 20 parts, Fructus Citri Sarcodactylis 10 parts, Herba Menthae 14 parts, Rhizoma Coptidis 19 parts, Flos Chrysanthemi Indici 12 parts, Margarita 16 parts, Flos Lonicerae 17 parts, Radix Salviae Miltiorrhizae 11 parts, Fructus Liquidambaris 15 parts, Cortex Dictamni 20 parts, Herba Houttuyniae 10 parts, Radix Et Rhizoma Rhei 14 parts, Herba Asari 18 parts, the Radix Angelicae Dahuricae 10 parts, 16 parts, Radix Glycyrrhizae, Flos Magnoliae 20 parts, Camphora 1 part, Radix Scrophulariae 13 parts, the Radix Paeoniae Alba 120 parts, nanometer silver 30 parts, Borneolum Syntheticum 9 parts, 3 parts, Moschus, Folium Perillae 14 parts, 80 parts, Cera Flava.
Will Homogeneous phase mixing after each component grinding above, the medicine to paste, both.
Embodiment 3
A kind of nanometer silver rhinitis ointment, comprise each component of following parts by weight: Radix Gentianae 10, Fructus Citri Sarcodactylis 15 parts, Herba Menthae 20 parts, Rhizoma Coptidis 11 parts, Flos Chrysanthemi Indici 14 parts, Margarita 19 parts, Flos Lonicerae 13 parts, Radix Salviae Miltiorrhizae 16 parts, Fructus Liquidambaris 19 parts, Cortex Dictamni 11 parts, Herba Houttuyniae 15 parts, Radix Et Rhizoma Rhei 17 parts, Herba Asari 12 parts, the Radix Angelicae Dahuricae 16 parts, 18 parts, Radix Glycyrrhizae, Flos Magnoliae 10 parts, Camphora 5 parts, Radix Scrophulariae 19 parts, the Radix Paeoniae Alba 14 parts, nanometer silver 55 parts, Borneolum Syntheticum 6 parts, 1 part, Moschus, Folium Perillae 16 parts, 80 parts, vaseline.
Will Homogeneous phase mixing after each component grinding above, the medicine to paste, both.
Embodiment 4
A kind of nanometer silver rhinitis ointment, comprise each component of following parts by weight: Radix Gentianae 16 parts, Fructus Citri Sarcodactylis 17 parts, Herba Menthae 14 parts, Rhizoma Coptidis 13 parts, Flos Chrysanthemi Indici 20 parts, Margarita 10 parts, Flos Lonicerae 16 parts, Radix Salviae Miltiorrhizae 18 parts, Fructus Liquidambaris 10 parts, Cortex Dictamni 16 parts, Herba Houttuyniae 15 parts, Radix Et Rhizoma Rhei 14 parts, Herba Asari 17 parts, the Radix Angelicae Dahuricae 10 parts, 15 parts, Radix Glycyrrhizae, Flos Magnoliae 0 part, Camphora 2 parts, Radix Scrophulariae 16 parts, the Radix Paeoniae Alba 18 parts, nanometer silver 75 parts, Borneolum Syntheticum 6 parts, 3 parts, Moschus, Folium Perillae 12 parts, 80 parts.
Will Homogeneous phase mixing after each component grinding above, the medicine to paste, both.
Experimental example
One, diagnostic criteria
The diagnostic criteria of acute sinusitis
There are acute rhinitis, influenza or acute infectious diseases history;
There are the symptoms such as general malaise, joint aches, lassitude, fever with chills;
Nasal obstruction, hyposmia, intranasal has a large amount of sticky purulence or purulent secretion, and headache can appear at forehead, glabella or occipitalia, hole chamber local pain;
Nasal cavity checks: nasal decongestion, concha nasalis enlargement, and middle nasal meatus and olfactory cleft have purulent secretion to overflow, and there is tenderness in nasal sinuses district;
X-ray checks: change sign in inflammatory;
Lab testing: total white blood cells and neutrophilic granulocyte number increase.
The diagnostic criteria of chronic sinusitis
There is acute nose (hole) scorching history of repeated attack;
Long-term nasal obstruction, the sticky pus of stream or pus tears, headache and dizziness, absent minded, hyposmia or disappearance;
Nasal cavity checks: nasal mucosa swelling or plumpness, and middle nasal concha enlargement or Polypoid changes, have sticky pus tears in the corresponding nasal meatus of sick hole;
X-ray checks: hole chamber is fuzzy, muddy, increase in density, pachymucosa or have liquid level: puncture or catheters irrigation has pus overflow.
Two, curative effect determinate standard
Recovery from illness: every day in nasal cavity 3-4 time, uses 5 days with this rhinitis ointment film continuously, without other drug, transference cure of having a headache and fever, mouth, nose, chamber check normally.
Effective: every day with this rhinitis ointment film in nasal cavity 3-4 time, use one week continuously, without other drug, flu disappearance, throat and nasal cavity inspection normally have mild inflammation.
Effective: use every day this rhinitis ointment film in nasal cavity 3-4 time, be no less than 5 times, after using 7 days continuously, do not use other drug, headache due to common cold alleviates, and throat and nasal cavity still have comparatively Mild edema, inflammation, sometimes still have nasal mucus.
Invalid: use every day this rhinitis ointment film in nasal cavity 3-4 time, it is invalid that continuous two weeks is still considered as without being clearly better.
Three, result judges
General effect: in 527 examples, wherein male 270 is routine, women 257 example, the oldest 60 years old, minimum 11 years old, the course of disease was the longest 14 days, the shortest 4 days.。
Acute and chronic nasal sinusitis: 104 examples, recovery from illness 93 example, accounts for 89.4%; Effective 7 examples, account for 6.7%; Effective 4 examples, account for 3.9%, effective percentage 100%.
Chronic rhinitis: 108 examples, recovery from illness 97 example, accounts for 89.8%; Effective 5 examples, account for 4.6%; Effective 6 examples, account for 5.6%, effective percentage 100%.
Chronic rhinitis companion nasal obstruction: 98 examples, recovery from illness 89 example, accounts for 90.8%; Effective 7 examples, account for 7.1%; Effective 2 examples, account for 2.1%, effective percentage 100%.
Acute rhinitis: 110 examples, recovery from illness 101 example, accounts for 91.8%; Effective 5 examples, account for 4.5%; Effective 2 examples, account for 1.8%, and invalid 2 examples, account for 1.8%, effective percentage 99.18%.
Acute rhinitis companion headache: 107 examples, recovery from illness 90 example, accounts for 84.1%; Effective 10 examples, account for 9.3%; Effective 4 examples, account for 3.7%, and invalid 3 examples, account for 2.8%, effective percentage 97.2%.
Amount in 527 examples 527 examples of fully recovering, account for 89.8%, effective 40 examples, account for 6.8%; Effective 19 examples, account for 3%, and invalid 1 example, accounts for 0.2%, total effective rate 99.83%.
Four, nanometer silver rhinitis ointment uses curative effect table
Sick kind Number of cases Recovery from illness Effective Effectively Invalid Total effective rate
Acute and chronic nasal sinusitis 104 93 7 4 0 100%
Chronic rhinitis 108 97 5 6 0 100%
Chronic rhinitis companion nasal obstruction 98 89 7 2 0 100%
Acute rhinitis 110 101 5 2 2 99.18%
Acute rhinitis companion headache 107 90 10 4 3 97.2%
Amount to 527 470 34 18 5 99.%
The foregoing is only better embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (7)

1. a nanometer silver rhinitis ointment, it is characterized in that, comprise each component of following parts by weight: Radix Gentianae 10 ~ 20 parts, Fructus Citri Sarcodactylis 10 ~ 25 parts, Herba Menthae 10 ~ 20 parts, Rhizoma Coptidis 10 ~ 20 parts, Flos Chrysanthemi Indici 10 ~ 20 parts, Margarita 10 ~ 20 parts, Flos Lonicerae 10 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 20 parts, Fructus Liquidambaris 10 ~ 20 parts, Cortex Dictamni 10 ~ 20 parts, Herba Houttuyniae 10 ~ 20 parts, Radix Et Rhizoma Rhei 10 ~ 20 parts, Herba Asari 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts, 10 ~ 20 parts, Radix Glycyrrhizae, Flos Magnoliae 10 ~ 20 parts, Camphora 1 ~ 10 part, Radix Scrophulariae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, nanometer silver 10 ~ 80 parts, Borneolum Syntheticum 1 ~ 10.
2. nanometer silver rhinitis ointment according to claim 1, is characterized in that: also comprise 1 ~ 10 part, Moschus.
3. nanometer silver rhinitis ointment according to claim 1, is characterized in that: also comprise Folium Perillae 10 ~ 20 parts.
4. nanometer silver rhinitis ointment according to claim 1, is characterized in that: also comprise 40 ~ 100 parts, vaseline, or 40 ~ 100 parts, Cera Flava.
5., according to the arbitrary described nanometer silver rhinitis ointment of Claims 1-4, it is characterized in that: nanometer silver is 20 ~ 40 parts.
6., according to the arbitrary described nanometer silver rhinitis ointment of Claims 1-4, it is characterized in that: nanometer silver is 25 ~ 60 parts.
7., according to the arbitrary described nanometer silver rhinitis ointment of Claims 1-4, it is characterized in that: nanometer silver is 50 ~ 80 parts.
CN201410830992.0A 2014-12-26 2014-12-26 A kind of Nano Silver rhinitis ointment Expired - Fee Related CN104587033B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395610A (en) * 2015-12-09 2016-03-16 刘传新 Preparation for treatment of rhinitis and production method thereof
CN109512863A (en) * 2018-12-11 2019-03-26 广东圣堂春中医学研究院 A kind of nasopharynx pot is formulated with pack
CN115487275A (en) * 2022-10-25 2022-12-20 湖南祥民制药有限公司 A Chinese medicinal granule containing Notoginseng radix extract and its preparation method

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CN101612280A (en) * 2009-07-16 2009-12-30 杨立光 A kind of unguentum that is used for the treatment of rhinitis and nasosinusitis
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CN101612280A (en) * 2009-07-16 2009-12-30 杨立光 A kind of unguentum that is used for the treatment of rhinitis and nasosinusitis
CN102258650A (en) * 2011-08-28 2011-11-30 陈晓阳 External rhinitis paste

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395610A (en) * 2015-12-09 2016-03-16 刘传新 Preparation for treatment of rhinitis and production method thereof
CN109512863A (en) * 2018-12-11 2019-03-26 广东圣堂春中医学研究院 A kind of nasopharynx pot is formulated with pack
CN115487275A (en) * 2022-10-25 2022-12-20 湖南祥民制药有限公司 A Chinese medicinal granule containing Notoginseng radix extract and its preparation method

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