CN108186867B

CN108186867B - Traditional Chinese medicine composition for treating viral influenza and preparation method thereof

Info

Publication number: CN108186867B
Application number: CN201810173538.0A
Authority: CN
Inventors: 王永保
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-03-05
Filing date: 2018-03-05
Publication date: 2021-03-05
Anticipated expiration: 2038-03-05
Also published as: CN108186867A

Abstract

The invention discloses a traditional Chinese medicine composition for treating viral influenza, which comprises the following components in parts by mass: 20-40 parts of honeysuckle, 10-20 parts of fructus forsythiae, 10-20 parts of dandelion, 10-20 parts of folium isatidis, 10-20 parts of radix isatidis, 10-20 parts of houttuynia cordata, 10-20 parts of scutellaria baicalensis, 10-20 parts of blackberry lily, 10-20 parts of gypsum, 10-20 parts of fritillaria, 5-15 parts of arisaema cum bile, 5-15 parts of almond, 5-15 parts of pinellia ternata, 5-15 parts of platycodon grandiflorum, 5-15 parts of loquat leaf, 5-15 parts of aster, 5-15 parts of inula flower, 5-15 parts of tussilago fara, 5-15 parts of radix bupleuri and 2-6 parts of liquorice. The traditional Chinese medicine components of the invention are scientifically compatible and cooperate, the immunity of a patient is obviously improved, and the invention has obvious effects of treating viral cold, high fever, myalgia, headache, cough, phlegm, dry cough, continuous breathing and sore throat.

Description

Traditional Chinese medicine composition for treating viral influenza and preparation method thereof

Technical Field

The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a traditional Chinese medicine composition for treating viral influenza and a preparation method thereof.

Background

Viral influenza is one of the most common diseases of the respiratory tract, and common viruses causing viral influenza include: influenza virus, rhinovirus, coronavirus, parainfluenza virus, respiratory syncytial virus, adenovirus and the like, which mainly show symptoms such as sneezing, nasal obstruction, pharyngalgia, cough, hoarseness and the like. Western medicines are not suitable for the symptoms and have insignificant treatment effect, and traditional Chinese medicines are increasingly and widely applied due to the advantages of unique theoretical basis, small toxic and side effects and the like.

However, the traditional Chinese medicine composition for treating viral influenza only has good treatment effect on a certain viral influenza. For example: patent CN102085311A discloses a Chinese medicinal composition for preventing or treating cold and/or influenza, which comprises honeysuckle, forsythia, mint, schizonepeta or schizonepeta spike, hypericum perforatum, burdock, platycodon grandiflorum, lophatherum gracile and liquorice; the Chinese medicinal composition has the effects of dispelling wind, relieving exterior syndrome, clearing heat and detoxicating, and has remarkable effects of resisting the influenza A HIN1 virus and inhibiting the avian influenza virus H9N 2.

Therefore, the development of the traditional Chinese medicine composition with the treatment effect on most viral colds has important significance.

Disclosure of Invention

The invention aims to solve the problems in the prior art and provides a traditional Chinese medicine composition for treating viral influenza and a preparation method thereof.

In order to achieve the aim, the invention provides a traditional Chinese medicine composition for treating viral influenza, which comprises the following components in parts by mass: 20-40 parts of honeysuckle, 10-20 parts of fructus forsythiae, 10-20 parts of dandelion, 10-20 parts of folium isatidis, 10-20 parts of radix isatidis, 10-20 parts of houttuynia cordata, 10-20 parts of scutellaria baicalensis, 10-20 parts of blackberry lily, 10-20 parts of gypsum, 10-20 parts of fritillaria, 5-15 parts of arisaema cum bile, 5-15 parts of almond, 5-15 parts of pinellia ternata, 5-15 parts of platycodon grandiflorum, 5-15 parts of loquat leaf, 5-15 parts of aster, 5-15 parts of inula flower, 5-15 parts of tussilago fara, 5-15 parts of radix bupleuri and 2-6 parts of liquorice.

Preferably, the composition also comprises the following components in parts by mass: 5-15 parts of radix angelicae.

Preferably, the composition also comprises the following components in parts by mass: 5-15 parts of burdock.

Preferably, the composition comprises the following components in parts by mass: 30 parts of honeysuckle, 15 parts of fructus forsythiae, 15 parts of dandelion, 15 parts of folium isatidis, 15 parts of radix isatidis, 15 parts of houttuynia cordata, 15 parts of scutellaria baicalensis, 15 parts of blackberrylily rhizome, 15 parts of gypsum, 15 parts of fritillaria, 10 parts of arisaema cum bile, 10 parts of almond, 10 parts of pinellia ternate, 10 parts of platycodon grandiflorum, 10 parts of loquat leaf, 10 parts of aster, 10 parts of inula flower, 10 parts of flos farfarae, 10 parts of radix bupleuri and 5 parts of liquorice.

The invention also provides a preparation method of the traditional Chinese medicine composition for treating viral influenza, which comprises the steps of crushing the traditional Chinese medicine components, sieving the crushed traditional Chinese medicine components with a 100-200-mesh sieve, adding the sieved traditional Chinese medicine components into water with the mass of 20-50 times of that of the crushed traditional Chinese medicine components, decocting the mixture for 2-3 times, and decocting the mixture for 20-40min each time, combining the filtrates, and decocting the mixed filtrate to obtain decoction.

The traditional Chinese medicine composition has the following effects:

honeysuckle flower: has the efficacies of clearing heat and removing toxicity, and is mainly used for treating warm disease fever, heat toxin bloody dysentery, carbuncle and ulcer, pyogenic infections, scrofula, anal fistula and other diseases.

Fructus forsythiae: has the effects of clearing away heat and toxic materials, relieving swelling and resolving hard mass, and can be used for treating carbuncle, cellulitis, scrofula, mammary abscess, erysipelas, wind-heat type common cold, early stage epidemic febrile disease, fever entering nutrient system, hyperpyrexia, polydipsia, coma, macula, heat stranguria, and anuresis.

Dandelion: has the effects of clearing away heat and toxic materials, relieving swelling, resolving hard mass, inducing diuresis for treating stranguria, and can be used for treating furuncle, pyogenic infection, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, pulmonary abscess, appendicitis, jaundice due to damp-heat pathogen, stranguria with astringency, etc.

Folium isatidis: has the effects of clearing away heat and toxic materials, cooling blood and removing speckle, and can be used for treating warm pathogen invasion, hyperpyrexia, coma, macula and erythra; jaundice, dysentery, mumps, sore throat, erysipelas, carbuncle and swelling.

Radix isatidis: has effects of clearing heat, removing toxic substance, cooling blood, and relieving sore throat, and can be used for treating influenza, epidemic encephalitis, encephalitis B, pneumonia, erysipelas, toxic heat, speckle, unconsciousness, hematemesis, pharyngeal swelling, mumps, pinkeye, sore rash, crimson dark tongue, pharyngitis, erysipelas of throat, fever with swollen head, epidemic febrile disease, carbuncle, etc., and preventing and treating epidemic encephalitis B, acute and chronic hepatitis, epidemic parotitis, osteomyelitis, etc.

Houttuynia cordata: has effects of clearing away heat and toxic materials, expelling pus, resolving carbuncle, inducing diuresis, and treating stranguria, and can be used for treating pneumonia, lung abscess, dysentery, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, rectocele, eczema, alopecia, scabies, and tinea.

Scutellaria baicalensis: has effects of clearing heat, eliminating dampness, clearing pathogenic fire, removing toxic substance, stopping bleeding, and preventing miscarriage, and can be used for treating chest distress, nausea, damp-heat distention, dysentery, jaundice, cough due to lung heat, hyperpyrexia, polydipsia, hematemesis, carbuncle, swelling, sore, and threatened abortion.

Shooting: has the effects of clearing away heat and toxic materials, eliminating phlegm and relieving sore throat, and can be used for treating heat-toxin phlegm-fire stagnation, sore throat, excessive phlegm and saliva, cough, asthma, etc.

Gypsum: has effects of clearing heat-fire, relieving restlessness and relieving cough, and can be used for treating common cold and fever, hyperpyrexia and vexation, cough and asthma due to lung heat, excessive stomach fire, headache, toothache, etc.

Fritillary bulb: the functions are mainly used for clearing heat and resolving masses, eliminating phlegm and relieving cough, and is used for treating wind-heat affecting lung, phlegm-fire cough, lung carbuncle, acute mastitis, scrofula, sore and other diseases.

Arisaema cum bile: the functions are mainly used for clearing heat, resolving phlegm, calming endogenous wind and arresting convulsion. Can be used for treating phlegm-heat cough, yellow and thick phlegm, apoplexy with phlegm, mania, and epilepsy.

Almond: has effects of eliminating phlegm, relieving cough, relieving asthma, moistening intestine, descending qi, and relieving arthralgia, and can be used for treating cough due to exogenous pathogenic factor, asthma, dryness-syndrome cough, cold and wind syndrome, infantile convulsion, thoracic obstruction, dyspepsia, epigastralgia, metrorrhagia, deafness, infantile malnutrition swelling, damp heat stranguria syndrome, scabies, pharyngitis, and constipation.

Pinellia ternata: has effects of eliminating dampness and phlegm, lowering adverse qi and relieving vomit, and relieving distension and fullness and resolving hard mass, and can be used for treating excessive phlegm cough and asthma, phlegm and fluid retention dizzy palpitation, wind phlegm giddiness, phlegm syncope headache, emesis regurgitation, chest and stomach fullness and stuffiness, globus hystericus, etc.

Balloon flower: has effects of dispersing lung qi, relieving sore throat, eliminating phlegm, and expelling pus, and can be used for treating cough with excessive phlegm, chest distress, pharyngalgia, hoarseness, lung carbuncle, suppuration, and pyocutaneous disease.

Loquat leaf: has effects of clearing lung-heat, relieving cough, lowering adverse flow of qi, and relieving vomit, and can be used for treating cough due to lung-heat, asthma, vomiting due to stomach-heat, dysphoria with smothery sensation, and thirst.

Aster root: has effects of warming lung, descending qi, eliminating phlegm, and relieving cough, and can be used for treating lung moistening, qi descending, phlegm eliminating, cough with dyspnea, cough with new and long-term symptoms, and cough with hemoptysis.

And (3) inula flower: has expectorant, dampness eliminating, and intestine smoothing effects, and can be used for treating phlegm, qi descending, hard mass softening, water retention, phlegm accumulation in chest, fullness in hypochondrium, cough and asthma, singultus, saliva such as resina Toxicodendri, epigastric fullness , belching, and abdominal edema.

And (3) common coltsfoot flower: has the effects of moistening lung, descending qi, eliminating phlegm and relieving cough, is mainly used for moistening lung, descending qi, relieving cough and eliminating phlegm, and is used for treating chronic cough, cough with dyspnea and excessive phlegm, cough with fatigue, hemoptysis and the like.

Radix angelicae: has the effects of dispelling pathogenic wind, removing dampness, promoting pus discharge, promoting granulation, promoting blood circulation, relieving pain, etc., and can be used for treating common cold, headache, supraorbital bone pain, nasal obstruction, nasosinusitis, toothache, leucorrhea, sore and ulcer, etc.

And (3) burdock: has the effects of dispelling wind and heat, clearing away heat and toxic materials, promoting eruption, dispersing lung qi, relieving sore throat, and relieving swelling, and can be used for treating wind and heat, lung qi, sore throat, and sore throat; can be used for treating wind-heat type common cold, cough with excessive phlegm, measles, rubella, sore throat, mumps, erysipelas, carbuncle, swelling, and suppurative sore.

Bupleurum root: has the effects of harmonizing exterior and interior, soothing liver-qi stagnation, invigorating yang and lifting subsidence, and clearing heat and preventing malaria, and can be used for treating common cold, fever, alternating chills and fever, distending pain in chest and hypochondrium, menoxenia, prolapse of son and sense organs, rectocele, etc.

Licorice root: the functions are mainly used for tonifying spleen and qi, clearing away heat and toxic materials, eliminating phlegm and stopping cough, relieving spasm and pain and harmonizing the medicines; can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, suppurative sore, and relieving drug toxicity and pungency.

A large number of animal acute toxicity tests, animal long-term toxicity tests and a large number of clinical tests for treating diseases are carried out on the composition, and scientific and objective basis is provided for the using link of the composition for treating the diseases. Experiments prove that the traditional Chinese medicine composition has no toxic or side effect.

The beneficial effects of the present invention will be further explained below in connection with clinical and typical cases.

1. General data

200 patients were treated with clinical observation, 105 male patients and 95 female patients aged 4-50 years all had viral influenza.

2. Method of treatment

The decoction prepared by the traditional Chinese medicine composition is orally taken once a day, and the decoction is taken in 2-3 times.

3. Criteria for efficacy assessment

The effect is shown: after 4 consecutive days, all cold symptoms disappeared.

The method has the following advantages: after continuous taking for 4 days, the main symptoms of cold are obviously relieved.

And (4) invalidation: after 4 days of continuous administration, the symptoms were not reduced or worsened.

4. Therapeutic results

153 cases of clinical significant effect account for 76.5 percent, 47 cases of clinical significant effect account for 23.5 percent, and the total effective rate is 100 percent.

Second, typical case

Case 1: for men, the age of 54 is 54, the pneumonia is infected by viral pneumonia in 2018 month 1, the pneumonia is determined by testing and X-ray of a first central hospital in Tianjin, the blood is infected by both viruses and bacteria, a virus treatment central doctor has no way, the bacteria are firstly treated by infusion, then the symptoms are fever more than 38 ℃, muscle pain throughout the body, cough is continuous, phlegm exists, levofloxacin and Mushutan are infused in the hospital for 4 days, the effect is not obvious, and all symptoms are finished after the prescription is taken for 4 days.

Case 2: the male, 31 years old, is infected with viral influenza in 2018 month 1, is determined to be viral influenza by testing in the first central hospital in Tianjin City, has symptoms of fever more than 38 degrees, general weakness, cough and phlegm, and has no effect when the patient says to drink the Shuanghuanglian oral liquid, and all symptoms are finished after 4 days of taking the prescription of the invention.

Case 3: for women, the age of 63 is 63, the patients are transfused for 21 days in the first central hospital in Tianjin city, the cold is not finished, and the symptoms of headache, nasal discharge, lacrimation, general weakness and muscle pain all disappear after the medicine is taken for 4 days.

Case 4: for men, the disease is 63 years old, the disease is infected with cold in 2014, the high fever is 39 degrees and 40 degrees, the high fever is not persistent, the whole body is painful after being infused for three days in a hospital, and all symptoms disappear after the medicine is taken for 4 days.

Case 5: in the case of men, the age of the male is 32 years old, and the male is infected with cold at the end of 2018, has headache, nasal discharge, phlegm and cough and is general and weak, and all symptoms disappear after the treatment of the formula disclosed by the invention for 4 days.

Case 6: in the age of 5 years old and at the end of 2018, 1 month, the male is infected with cold, fever, headache, rhinorrhea, phlegm, cough and general weakness, and all symptoms disappear after continuously taking the formula for 4 days.

Case 7: 30 female, 30 in SARS epidemic, the result of the test in hospital is H7N7 virus, when he takes the prescription of the invention, he also transfuses anti-inflammatory drugs, after one week of treatment, all cold symptoms still have H7N7 virus, and after the test in hospital, all the virus disappears.

The invention has the beneficial effects that:

(1) according to the formula of the traditional Chinese medicine composition, honeysuckle is used as a monarch drug, fructus forsythiae, dandelion, folium isatidis, radix isatidis and houttuynia cordata are used as ministerial drugs, influenza virus is resisted and treated, scutellaria baicalensis, blackberry lily, gypsum, fritillaria, arisaema cum bile, almond, pinellia ternate, platycodon grandiflorum, loquat leaf, aster, inula flower, flos farfarfarae, angelica dahurica, burdock, radix bupleuri and liquorice are used as auxiliary drugs, and scutellaria baicalensis, blackberry lily and gypsum clear lung heat and treat pharyngitis and pain; fritillary, arisaema cum bile, almond, pinellia ternate, platycodon grandiflorum, loquat leaf, aster, inula flower and tussilago farfara, and has the effects of relieving exterior syndrome and treating wind-cold type common cold, headache and nasal obstruction, and the burdock is used in spring and summer and has the effects of relieving exterior syndrome and treating wind-heat type common cold and sore throat; radix bupleuri has the effects of relieving exterior syndrome, reducing fever, resisting inflammation, resisting virus and upper respiratory tract infection, and regulating the drug properties of the medicines; the main cause of the viral influenza is virus, the virus is removed, and the natural diseases are completely disappeared.

(2) The traditional Chinese medicine components of the invention are scientifically compatible and cooperate, the immunity of a patient is obviously improved, and the invention has obvious effects of treating various viral colds, high fever, myalgia, headache, cough, phlegm, dry cough, continuous breathing and sore throat.

Detailed Description

The present invention will be explained in detail with reference to examples.

Example 1

A traditional Chinese medicine composition for treating viral influenza comprises the following components: 20g of honeysuckle, 10g of fructus forsythiae, 10g of dandelion, 10g of folium isatidis, 10g of radix isatidis, 10g of houttuynia cordata, 10g of scutellaria baicalensis, 10g of blackberrylily rhizome, 10g of gypsum, 10 parts of fritillaria, 5 parts of arisaema cum bile, 5g of almond, 5g of pinellia ternate, 5g of platycodon grandiflorum, 5g of loquat leaf, 5g of aster, 5g of inula flower, 5g of flos farfarae, 5g of radix angelicae (used only in autumn and winter), 5g of fructus arctii (used only in spring and summer), 5g of radix bupleuri and 2g of liquorice.

The preparation method of the traditional Chinese medicine composition for treating viral influenza comprises the following steps: pulverizing the Chinese medicinal materials, sieving with 200 mesh sieve, adding into water 20 times of the weight of the Chinese medicinal materials, decocting for 3 times (each time for 30 min), mixing filtrates, and decocting to obtain decoction.

Example 2

A traditional Chinese medicine composition for treating viral influenza comprises the following components: 30g of honeysuckle, 15g of fructus forsythiae, 15g of dandelion, 15g of folium isatidis, 15g of radix isatidis, 15g of houttuynia cordata, 15g of scutellaria baicalensis, 15g of blackberrylily rhizome, 15g of gypsum, 15g of fritillaria, 10g of arisaema cum bile, 10g of almond, 10g of pinellia ternate, 10g of platycodon grandiflorum, 10g of loquat leaf, 10g of aster, 10g of inula flower, 10g of flos farfarae, 10g of radix angelicae (used only in autumn and winter), 10g of burdock (used only in spring and summer), 10g of radix bupleuri and 5g of liquorice.

The preparation method of the traditional Chinese medicine composition for treating viral influenza comprises the following steps: pulverizing the Chinese medicinal components, sieving with 100 mesh sieve, adding 40 times of water, decocting for 2 times (each time for 40 min), mixing filtrates, and decocting to obtain decoction.

Example 3

A traditional Chinese medicine composition for treating viral influenza comprises the following components: 40g of honeysuckle, 20g of fructus forsythiae, 20g of dandelion, 20g of folium isatidis, 20g of radix isatidis, 20g of houttuynia cordata, 20g of scutellaria baicalensis, 20g of blackberrylily rhizome, 20g of gypsum, 20 parts of fritillaria, 15g of arisaema cum bile, 15g of almond, 15g of pinellia ternate, 15g of platycodon grandiflorum, 15g of loquat leaf, 15g of aster, 15g of inula flower, 15g of tussilago farfara, 15g of radix angelicae (used only in autumn and winter), 15g of burdock (used only in spring and summer), 15g of radix bupleuri and 6g of liquorice.

The preparation method of the traditional Chinese medicine composition for treating viral influenza comprises the following steps: pulverizing the Chinese medicinal components, sieving with 100 mesh sieve, adding 50 times of water, decocting for 2 times (each time for 20 min), mixing filtrates, and decocting to obtain decoction.

The prescription in the embodiment 2 of the invention is used by 100 kg of adults, the weight is increased and decreased proportionally, the medicine is generally taken from 4 to 7 for curing, the dose is taken by one fourth from 3 to 8 years old, the medicine is good after 4 days, and the medicine is half-used for the aged from 8 to 18 and the aged over 60, and the medicine is good after 4 days.

5g of honeysuckle, 3g of dandelion, 3g of folium isatidis, 3g of houttuynia cordata and 5g of fritillaria are used by children under 1-3 years old, decocted and then added with honey or white sugar for 3 days.

The traditional Chinese medicine composition is prepared into other dosage forms such as aqua, ointment, pill and the like, and is within the protection scope of the patent.

The invention is not limited to the above preferred embodiments, but includes all modifications, equivalents, and simplifications that may be made by those skilled in the art without departing from the spirit of the invention.

Claims

1. A traditional Chinese medicine composition for treating viral influenza is characterized in that: the composition is prepared from the following components in parts by mass: 30g of honeysuckle, 15g of fructus forsythiae, 15g of dandelion, 15g of folium isatidis, 15g of radix isatidis, 15g of houttuynia cordata, 15g of scutellaria baicalensis, 15g of blackberrylily rhizome, 15g of gypsum, 15g of fritillaria, 10g of arisaema cum bile, 10g of almond, 10g of pinellia ternate, 10g of platycodon grandiflorum, 10g of loquat leaf, 10g of aster, 10g of inula flower, 10g of flos farfarae, 10g of radix angelicae or burdock, 10g of radix bupleuri and 5g of liquorice;