CN104274617A - Traditional Chinese medicine composition for nursing treatment of acute cervicitis - Google Patents
Traditional Chinese medicine composition for nursing treatment of acute cervicitis Download PDFInfo
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- CN104274617A CN104274617A CN201410595739.1A CN201410595739A CN104274617A CN 104274617 A CN104274617 A CN 104274617A CN 201410595739 A CN201410595739 A CN 201410595739A CN 104274617 A CN104274617 A CN 104274617A
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Classifications
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Abstract
The invention discloses a traditional Chinese medicine composition for nursing treatment of acute cervicitis, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 8-13 parts of dandelion, 8-13 parts of roots of Chinese pulsatilla, 4-8 parts of semen plantaginis, 4-8 parts of oldenlandia diffusa, 4-8 parts of herba patriniae, 8-13 parts of fructus cnidii, 4-8 parts of golden cypress, 4-8 parts of frankincense, 8-13 parts of myrrh, 8-13 parts of coptis chinensis, 5-7 parts of folium callicarpae pedunculalae and 5-7 parts of sculellaria barbata. The traditional Chinese medicine composition disclosed by the invention can promote cervicitis inflammation absorption and block or reverse development of acute cervicitis, and is lasting in action, free of a side effect and consolidated in curative effect, and both symptoms and root causes are treated.
Description
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine composition of nursing for treating acute cervicitis.
Background technology
Chronic cervicitis is modal one in gynaecopathia, and after being more common in childbirth, miscarriage or surgical injury cervix uteri, pathogen invades and causes infection, and is changed by acute cervicitis.Acute cervicitis treatment is thorough often, and pathogen is lived in seclusion and form chronic inflammatory disease in cervical mucosa.The acute inflammation that acute cervicitis (acute cervieitis) causes for pathogenic infection cervix uteri.Be mainly seen in septic abortion, obstetric infection, unclean sexual activity, cervical lesions or vaginal foreign body, pathogenic substance enters and infects.Show as cervix uteri redness, the hyperemia of cervical canal mucosa, edema, purulent secretion can flow out through cervical orifice.The congestion of blood vessel is seen, a large amount of polymorphonuclear leukocyte infiltration around cervical mucosal and sub-mucosal tissues, body of gland, visible purulent secretion in lumen of gland under mirror.Pathogenic factor has: 1. anthropic factor, and (1) medical worker is careless, leaves over gauze, cotton balls or other foreign bodies, be easy to bring out infection and cause acute cervicitis during overlong time in birth canal; (2), during some operation on cervix, the damage of cervix dilating or perforation, and the damage of cervix uteri or palace body when diagnostic scrapes uterus are also one of cause of disease of acute cervicitis.2. pathogen factor, modal be staphylococcus, the suppurative inflammation that causes of escherichia coli, streptococcus, Diplococcus gonorrhoeae and chlamydia trachomatis, bacillus pyocyaneus etc., virus, infusorian etc. all can cause cervicitis.3. mechanical irritation or damage: childbirth or the laceration of cervix secondary infection that causes of miscarrying be acute cervicitis commonly encountered diseases because of.4. when acute trichomonal vaginitis or colpitis mycotica, bacterial vaginitis occur vagina, also can cause acute cervicitis disease simultaneously; Also acute gonococcal cervicitis is often there is in gonorrhea diplococcus when infecting.5. chemical substance stimulates: the acidity of unsuitable use high concentration or alkaline medicine liquid washing vagina etc. all can cause acute cervicitis.
Naturopathy is current widely used a kind of Therapeutic Method, has short treating period, eutherapeutic advantage.Be applicable to the case that inflammation is comparatively serious and inflammatory infiltration is darker, conventional means has electricity to press art, laser therapy or cryotherapy.But shortcoming is that relapse rate is high.Operative treatment only has when older, cureless cervicitis or doubtful precancerous lesion person take into account row cervicitis operative treatment.But in fact just to the vital interests of patient, easily cause apparatus to infect, produce larger injury to cervix uteri, vaginal dilator is exactly one of them, if disease is not very serious, had better not at will perform the operation, treatment cervicitis, operation there be limited evidence currently of uses.
Chinese medicine is had great advantage by dialectical treatment acute cervicitis, and therefore by a kind of Chinese patent medicine for the treatment of acute cervicitis of research and development, this seems very urgent.
Summary of the invention
The present invention according to Traditional Chinese medical theory, through to a large amount of screenings of drug component, restructuring, trial, made by lot of experiments again.Therefore, the object of the present invention is to provide a kind of Chinese medicine composition of more safe and reliable treatment acute cervicitis.
The object of the present invention is achieved like this:
The Chinese medicine composition of a kind of nursing for treating acute cervicitis of the present invention, is prepared from by the Chinese crude drug of following weight portion: Herba Taraxaci 8-13 part, Radix Pulsatillae 8-13 part, Semen Plantaginis 4-8 part, Herba Hedyotidis Diffusae 4-8 part, Herba Patriniae 4-8 part, Fructus Cnidii 8-13 part, Cortex Phellodendri 4-8 part, Olibanum 4-8 part, Myrrha 8-13 part, Rhizoma Coptidis 8-13 part, Folium Callicarpae Formosanae 5-7 part, Herba Scutellariae Barbatae 5-7 part.
In a most preferred embodiment, the Chinese medicine composition of described nursing for treating acute cervicitis, is prepared from by the Chinese crude drug of following weight portion: Herba Taraxaci 10 parts, the Radix Pulsatillae 10 parts, Semen Plantaginis 6 parts, Herba Hedyotidis Diffusae 6 parts, Herba Patriniae 6 parts, Fructus Cnidii 10 parts, Cortex Phellodendri 6 parts, Olibanum 6 parts, Myrrha 10 parts, Rhizoma Coptidis 10 parts, Folium Callicarpae Formosanae 6 parts, Herba Scutellariae Barbatae 6 parts.
Further preferably, the Chinese medicine composition of described nursing for treating acute cervicitis is oral formulations.
Again further preferably, the Chinese medicine composition of described nursing for treating acute cervicitis is oral liquid, granule, tablet or capsule.
Found by clinical application research, the pharmaceutical composition be prepared from by above-mentioned Chinese crude drug obtains satisfied curative effect in treatment acute cervicitis patient.Therefore, second object of the present invention is to provide a kind of new medical use, the application of namely above-mentioned Chinese medicine composition in the Chinese medicine of preparation treatment acute cervicitis.
According to Chinese medicine Historical Data Data About, above-mentioned Chinese crude drug has following pharmacologically active and function cures mainly:
Herba Taraxaci: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, have inhibitory action to staphylococcus aureus, Bacillus typhi, is used for the treatment of liver-heat conjunctival congestion and swelling pain, and multi-infection, purulent disease.Be selected from the herb of dry Herba Taraxaci.
Semen Plantaginis: clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminates the phlegm.For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.Select the dry mature seed of Plantaginaceae plant Herba Plantaginis or Plantago depressa Willd.
The Radix Pulsatillae: there is heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, effect of removing dampness and killing parasites.Note controls pyretic toxicity dysentery, epistaxis, internal hemorrhoid with bleeding, leukorrhagia, pudendal pruritus, carbuncle skin ulcer, scrofula.Select the dry root of ranunculaceae plant Radix Pulsatillae Pulsatilla chinensis (Bge.) Regel.
Herba Hedyotidis Diffusae: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, inducing diuresis to remove edema.For laryngopharynx swelling and pain, dyspnea and cough due to lung-heat, the puckery pain of pyretic stranguria, jaundice due to damp-heat, venom, skin ulcer swells hot carbuncle.Select the dry herb of Maguireothamnus speciosus Herba Hedyotidis Diffusae Hedyotis diffusa Willd..
Herba Patriniae: heat-clearing and toxic substances removing, detumescence and apocenosis, cooling blood for hemostasis.Cure mainly acute appendicitis, lung abscess, cough due to lung-heat, enteritis, dysentery disease, cholecystitis, pelvic inflammatory disease, furuncle toxic swelling, eczema scrotum, haematemesis, epistaxis, metrorrhagia, the traumatic injury person of dragging for wound.Select dry herb or the root of feverfew Herba Ixeritis chinensis.
Fructus Cnidii: warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago, vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.Select the dry mature fruit of samphire cnidium monnieri Cnidium monnieri (L.) Cuss..
Cortex Phellodendri: heat-clearing and toxic substances removing, heat clearing and damp drying.Cure mainly hygropyretic dysentery, have loose bowels, jaundice; Nocturnal emission, stranguria with turbid discharge, leukorrhagia; Hectic fever due to YIN-deficiency consumptive fever, night sweat; And aphtha of the mouth and tongue; Conjunctival congestion and swelling pain; Skin sore; Skin eczema.Select the bark of rutaceae Cortex Phellodendri or wampee.
Olibanum: regulating qi and activating blood, analgesic therapy, chases after poison, has strong bacteriostasis, and effectively can kill infusorian.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select the scented resin containing volatile oil of olive subject plant Olibanum wood (Boswellia thurifera or Boswellia sacra) output.
Myrrha: loose blood blood stasis removing, subduing swelling and relieving pain.Cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, mass in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There is the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation.Select the gum resin of olive subject plant myrrh CommiphoramyrrhaEngl. or Alan fort myrrh.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; Select the dry rhizome of cohosh Rhizoma Coptidis (Coptis chinensis Franch.), Coptis deltoidea C.Y.Cheng et Hsiao (Coptis deltoidea C. Y. Cheng et Hsiao) and Coptis Teeta Wall (Coptis teeta Wall.).
Folium Callicarpae Formosanae: have heat-clearing and toxic substances removing, cooling blood for hemostasis, dephlogistication and promoting nuscle growth, the Peculiar function such as anticancer, Folium Callicarpae Formosanae has inhibitory action to escherichia coli, bacterium flexneri, staphylococcus aureus, streptococcus etc., otch hemorrhage and postoperative hemorrhage when can be used for treatment gastrointestinal hemorrhage, surgical operation.The dry root of Herba Verbenae Callicarpa plant Folium Callicarpae Macrophyllae Callicarpa macrophylla Vah and leaf is selected to be used as medicine.
Herba Scutellariae Barbatae: the hemostasis of heat-clearing and toxic substances removing, dissipating blood stasis, inducing diuresis to remove edema.Cure mainly pyretic toxicity carbuncle, have sore throat, lung abscess, acute appendicitis, scrofula, venom, traumatic injury, haematemesis, epistaxis, stranguria with blood, edema, ascites and cancer.Select the dry herb of labiate Herba Scutellariae Barbatae.
Above-mentioned each Chinese crude drug is prepared into the preparation method of compound oral liquid of the present invention, comprise the steps: to take and clean up and the Herba Taraxaci of drying, the Radix Pulsatillae, Semen Plantaginis, Herba Hedyotidis Diffusae, Herba Patriniae, Fructus Cnidii, Cortex Phellodendri, Olibanum, Myrrha, Rhizoma Coptidis, Folium Callicarpae Formosanae, Herba Scutellariae Barbatae, merge, decoct with water twice, collecting decoction, when being evaporated to 70 DEG C, relative density is 1.15-1.20, adding ethanol makes the percent by volume of alcohol content reach 75-85%, stir, leave standstill, filter, during filtrate reduced in volume to 70 DEG C, relative density is 1.10-1.20 and reclaims ethanol to obtain concentrated solution, concentrated solution to be added water and auxiliaries becomes oral liquid.
Compared with prior art, tool of the present invention has the following advantages and progress significantly: (1) good effect.Found by a large amount of clinical practices, the Chinese medicine composition that the present invention relates to can not only promote cervicitis site absorption, blocks or reverse acute cervicitis development, and persistent, and treating both the principal and secondary aspects of a disease, has no side effect, efficacy consolidation.Further, lot of experiments research display, most acute cervicitis patient takes medicine of the present invention and namely occurs obvious curative effects 1 course for the treatment of.(2) safety is high.Because medicine of the present invention is prepared from by adopting Chinese medicine material, toxicity is low, and patient medication is safer.
Detailed description of the invention
The present invention is further illustrated below by embodiment.Embodiments of the invention are only used for the present invention is described, instead of limitation of the present invention, under concept thereof of the present invention, all belong to the scope of protection of present invention to the simple modifications of preparation method of the present invention.
Embodiment 1 prepares the Chinese medicine composition oral liquid of nursing for treating acute cervicitis
Crude drug prescription: Herba Taraxaci 10 parts, the Radix Pulsatillae 10 parts, Semen Plantaginis 6 parts, Herba Hedyotidis Diffusae 6 parts, Herba Patriniae 6 parts, Fructus Cnidii 10 parts, Cortex Phellodendri 6 parts, Olibanum 6 parts, Myrrha 10 parts, Rhizoma Coptidis 10 parts, Folium Callicarpae Formosanae 6 parts, Herba Scutellariae Barbatae 6 parts.Preparation method: the medical material taking above-mentioned recipe quantity merges, decoct with water twice, first time adds water as 10 times amount of medical material weight, decoct 2h, second time adds water as 8 times amount of medical material weight, decoct 1.5h, collecting decoction, 0.08MPa, relative density is 1.15 when being evaporated to 70 DEG C at 70 DEG C, adds 95% (v/v) ethanol and makes alcohol content reach 75% (v/v), stir, hold over night, filter, under 0.08MPa, 65 DEG C of conditions, concentrating under reduced pressure becomes filtrate is 1.15g/mL to relative density when 65 DEG C, adds water and sucrose is mixed with oral liquid.
Embodiment 2 prepares the Chinese medicine composition oral liquid of nursing for treating acute cervicitis
Crude drug prescription: Herba Taraxaci 13 parts, the Radix Pulsatillae 13 parts, Semen Plantaginis 7 parts, Herba Hedyotidis Diffusae 7 parts, Herba Patriniae 7 parts, Fructus Cnidii 11 parts, Cortex Phellodendri 7 parts, Olibanum 7 parts, Myrrha 10 parts, Rhizoma Coptidis 10 parts, Folium Callicarpae Formosanae 6 parts, Herba Scutellariae Barbatae 6 parts.
Preparation method: the medical material taking above-mentioned recipe quantity merges, decoct with water twice, first time adds water as 10 times amount of medical material weight, decoct 2h, second time adds water as 8 times amount of medical material weight, decoct 1.5h, collecting decoction, 0.08MPa, relative density is 1.15 when being evaporated to 70 DEG C at 70 DEG C, adds 95% (v/v) ethanol and makes alcohol content reach 85% (v/v), stir, hold over night, filter, under 0.08MPa, 65 DEG C of conditions, concentrating under reduced pressure becomes filtrate is 1.15g/mL to relative density when 65 DEG C, adds water and sucrose is mixed with oral liquid.
Embodiment 3 prepares the Chinese medicine composition oral liquid of nursing for treating acute cervicitis
Crude drug prescription: Herba Taraxaci 8 parts, the Radix Pulsatillae 11 parts, Semen Plantaginis 8 parts, Herba Hedyotidis Diffusae 7 parts, Herba Patriniae 7 parts, Fructus Cnidii 11 parts, Cortex Phellodendri 8 parts, Olibanum 8 parts, Myrrha 11 parts, Rhizoma Coptidis 11 parts, Folium Callicarpae Formosanae 6 parts, Herba Scutellariae Barbatae 6 parts.
Preparation method: the medical material taking above-mentioned recipe quantity merges, decoct with water twice, first time adds water as 10 times amount of medical material weight, decoct 2h, second time adds water as 8 times amount of medical material weight, decoct 1.5h, collecting decoction, 0.08MPa, relative density is 1.20 when being evaporated to 70 DEG C at 70 DEG C, adds 95% (v/v) ethanol and makes alcohol content reach 80% (v/v), stir, hold over night, filter, under 0.08MPa, 65 DEG C of conditions, concentrating under reduced pressure becomes filtrate is 1.15g/mL to relative density when 65 DEG C, adds water and sucrose is mixed with oral liquid.
Embodiment 4 Chinese medicine composition of the present invention is to the effectiveness study of acute cervicitis patient
Chinese medicine oral liquid sample preparation: take Herba Taraxaci 10 parts, the Radix Pulsatillae 10 parts, Semen Plantaginis 6 parts, Herba Hedyotidis Diffusae 6 parts, Herba Patriniae 6 parts, Fructus Cnidii 10 parts, Cortex Phellodendri 6 parts, Olibanum 6 parts, Myrrha 10 parts, Rhizoma Coptidis 10 parts, Folium Callicarpae Formosanae 6 parts, Herba Scutellariae Barbatae 6 parts, the medical material of above-mentioned recipe quantity is merged, decoct with water twice, first time adds water as 10 times amount of medical material weight, decoct 2h, second time adds water as 8 times amount of medical material weight, decoct 1.5h, collecting decoction, 0.08MPa, when being evaporated to 70 DEG C at 70 DEG C, relative density is 1.15, adding 95% (v/v) ethanol makes alcohol content reach 75% (v/v), stir, hold over night, filter, filtrate is at 0.08MPa, under 65 DEG C of conditions, concentrating under reduced pressure one-tenth is 1.15g/mL to relative density when 65 DEG C, .
The experimenter of this test is determined: (1) cervix uteri is red and swollen, and vaginal secretions increases, petechial hemorrhage, and leucorrhea is pus according to " TCM Gynecology disease Standardization of diagnosis and curative effect "; (2) with lower abdomen and lumbosacral region pendant pain, the irritative symptoms such as frequent micturition, urgent micturition, dysurea; (3) heating, malaise, other acute cervicitis diseases such as uterus and adnexa tenderness.50 acute cervicitis female patients, minimum 25 years old of age, maximum 55 years old; Slight 7 examples, moderate 28 example, severe 15 example.The Chinese medicine oral liquid sample that all patients give to prepare as stated above carries out Drug therapy, and sooner or later respectively take medicine once, each 20mL(can dilute rear sugaring and take).30d is 1 course for the treatment of, treats 1 ~ 3 course for the treatment of, the pungent stimulation food of period in a medicine fasting, and mood keeps happy.
With reference to the curative effect determinate standard of acute cervicitis in " up-to-date domestic and international disease treatment standard ", determine as follows to the criterion of therapeutical effect after treatment of the present invention:
Cure: red and swollen without cervix uteri, vaginal secretion is normal, without lower abdomen and lumbosacral region pendant pain, without symptoms such as heating, frequent micturitions, within after drug withdrawal 3 months, does not recur.
Effective: red and swollen without cervix uteri, vaginal secretion is normal, without lower abdomen and lumbosacral region pendant pain, without symptoms such as heating, frequent micturitions.
Effective: red and swollen without cervix uteri, leucorrhea is creamy white mucus shape, occasionally has lower abdomen and lumbosacral region pendant pain.
Invalid: cervix uteri is red and swollen, and vaginal secretions is many, petechial hemorrhage, and leucorrhea is purulence, lower abdomen and lumbosacral region pendant pain, with irritative symptoms such as frequent micturition, urgent micturition, dysureas, heating, malaise, uterus and adnexa tenderness etc., and symptom has the trend increased the weight of.
Result: cure 19 examples, effective 23 examples, effective 5 examples, invalid 3 examples, effective percentage reaches 94%.
Found by a large amount of clinical practices, the Chinese medicine composition persistent that the present invention relates to, treating both the principal and secondary aspects of a disease, have no side effect, efficacy consolidation, and, lot of experiments research display, most acute cervicitis patient takes medicine of the present invention and namely occurs obvious curative effects 1 course for the treatment of.
Claims (5)
1. a Chinese medicine composition for nursing for treating acute cervicitis, is characterized in that being prepared from by the Chinese crude drug of following weight portion: Herba Taraxaci 8-13 part, Radix Pulsatillae 8-13 part, Semen Plantaginis 4-8 part, Herba Hedyotidis Diffusae 4-8 part, Herba Patriniae 4-8 part, Fructus Cnidii 8-13 part, Cortex Phellodendri 4-8 part, Olibanum 4-8 part, Myrrha 8-13 part, Rhizoma Coptidis 8-13 part, Folium Callicarpae Formosanae 5-7 part, Herba Scutellariae Barbatae 5-7 part.
2. the Chinese medicine composition of nursing for treating acute cervicitis according to claim 1, is characterized in that being prepared from by the Chinese crude drug of following weight portion: Herba Taraxaci 10 parts, the Radix Pulsatillae 10 parts, Semen Plantaginis 6 parts, Herba Hedyotidis Diffusae 6 parts, Herba Patriniae 6 parts, Fructus Cnidii 10 parts, Cortex Phellodendri 6 parts, Olibanum 6 parts, Myrrha 10 parts, Rhizoma Coptidis 10 parts, Folium Callicarpae Formosanae 6 parts, Herba Scutellariae Barbatae 6 parts.
3. the Chinese medicine composition of nursing for treating acute cervicitis according to claim 1 and 2, is characterized in that: described Chinese medicine composition is oral formulations.
4. the Chinese medicine composition of nursing for treating acute cervicitis according to claim 3, is characterized in that: described Chinese medicine composition is oral liquid, granule, tablet or capsule.
5. the application of Chinese medicine composition in the medicine of preparation treatment acute cervicitis of the nursing for treating acute cervicitis described in claim 1 or 2.
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| CN104940410A (en) * | 2015-07-21 | 2015-09-30 | 陈�峰 | Traditional Chinese medicine composition for treating cervicitis and preparation method and application thereof |
| CN108245590A (en) * | 2018-04-16 | 2018-07-06 | 胡碧原 | A kind of Chinese medicine for treating septic abortion |
| CN118236426A (en) * | 2024-03-22 | 2024-06-25 | 青州仰天山中药材种植开发专业合作社 | Gynecological antibacterial liquid and method for treating leukorrhagia by combining with manipulation of rubbing tendons and dredging collaterals |
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| CN101549099A (en) * | 2009-05-15 | 2009-10-07 | 高月兰 | Traditional Chinese medicine for treating cervicitis |
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| CN101549099A (en) * | 2009-05-15 | 2009-10-07 | 高月兰 | Traditional Chinese medicine for treating cervicitis |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104940410A (en) * | 2015-07-21 | 2015-09-30 | 陈�峰 | Traditional Chinese medicine composition for treating cervicitis and preparation method and application thereof |
| CN108245590A (en) * | 2018-04-16 | 2018-07-06 | 胡碧原 | A kind of Chinese medicine for treating septic abortion |
| CN118236426A (en) * | 2024-03-22 | 2024-06-25 | 青州仰天山中药材种植开发专业合作社 | Gynecological antibacterial liquid and method for treating leukorrhagia by combining with manipulation of rubbing tendons and dredging collaterals |
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