CN105535674A

CN105535674A - A medicine for treating chronic cervicitis

Info

Publication number: CN105535674A
Application number: CN201510973104.5A
Authority: CN
Inventors: 许梅
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-23
Filing date: 2015-12-23
Publication date: 2016-05-04

Abstract

A medicine for treating chronic cervicitis is provided. Raw material medicines comprise common cnidium fruit, amur cork-tree, root and vine of manyprickle acanthopanax, scabrous elephantfoot, szechwan chinaberry fruit, fleeceflower root, dahurian angelica root, atractylodes rhizome, draconis resin, spikemoss, sappan wood, coix seed, heterophylly falsestarwort root, bigfruit phymatopsis herb, lightyellow sophora root, borneol, honeysuckle bud and flower, herba houttuyniae, hemisteptia lyrata, asiatic cornelian cherry fruit, dodder seed, cockcomb inflorescence, myrrh, common knotgrass herb, sargentgloryvine stem and teucrium quadrifarium. The medicine is prepared into an external application dosage form and an oral administration dosage form. Through combined internal and external medicine administration, cervical erosion is effectively treated, waist bone pains, abdomen tenesmus and other related clinical symptoms are obviously improved and quality of life of a patient is improved. The medicine is safe, reliable and free of obvious untoward effects.

Description

Be used for the treatment of the medicine of chronic cervicitis

Technical field

The present invention relates to technical field of Chinese medicine, particularly relate to a kind of medicine being used for the treatment of chronic cervicitis.

Background technology

Chronic cervicitis is one of common gynecological disease and frequently-occurring disease, how to be transferred by acute cervicitis, and after childbirth, miscarriage, surgical injury cervix uteri, the pathogen such as staphylococcus, streptococcus, escherichia coli invade infection and cause.Clinical manifestation is mainly that vaginal secretions increases, contact bleeding, sanguinous leukorrhea etc., the clinical specific treatment that there is no at present, suits the medicine to the illness Supporting Therapy in the local that adopts more.

Chronic cervicitis mostly is acute cervicitis and does not treat or thoroughly do not cure caused by delay.Main pathogens is staphylococcus, streptococcus, escherichia coli etc., and often after childbirth, miscarriage equivalent damage cervix uteri, cervical surface barrier action is destroyed, and pathogen is invaded and causes infecting.Clinically adopt naturopathy at present more, but naturopathy require through after 2 ~ 7d carry out, and a large amount of discharge opeing of normal companion's vagina after treatment, even hemorrhage.

Chronic cervicitis pathological changes is based on cervix uteri local patholoic change, and cervical erosion is local pathological characters the most common in chronic cervicitis pathological process, and local is red, swollen, has ulcer.

According to its main clinical manifestation profuse leukorrhea or as pus as tears or leukorrhagia red white or belong to " leukorrheal diseases " category of the traditional Chinese medical science with diseases such as pruritus vulvaes.This pathogenesis is damp and hot conjunction with insect poison and changes corruption, and congestion blocks, and erosion blood flesh slough is rotten, and dislike meat and do not go, the not life of new flesh, and cause cervical erosion, sepage is outflowed, and redly holds concurrently mutually in vain, and turbid band outflow vagina, and stain turbid yin portion, cause pruritus vulvae.Visible " wet, heat, poison " heresy is the Chinese pathology essence of chronic cervicitis.Treatment should to change local functional status.According to tcm theory, this is that rotten silt of flesh is deposited, and waste heat is most, and flesh is difficult raw pathomechanism, and treatment emphasis should at clearing away heat-damp and promoting diuresis, silt of invigorating blood circulation, parasite killing removing toxic substances, astringing to arrest bleeding, putrefaction-removing granulation-promoting sore, and heat then can be stopped blooding clearly, and silt is gone can granulation promoting.

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of medicine being used for the treatment of chronic cervicitis, be prepared into exterior-applied formulation and dosage form for oral administration, by inside and outside drug combination, effectively can not only treat cervical erosion, and obviously can alleviate the associated clinical symptoms such as waist bones of the body portion pain, abdominal part tenesmus, improve the life quality of patient, and it is safe and reliable, without obvious adverse reaction, therefore, clinic is applied.

For solving the problems of the technologies described above, the invention provides a kind of medicine being used for the treatment of chronic cervicitis, its crude drug comprises Fructus Cnidii, Cortex Phellodendri, Radix Et Caulis Acanthopanacis Senticosi, Elephantopus scaber L., Fructus Toosendan, Radix Polygoni Multiflori, the Radix Angelicae Dahuricae, Rhizoma Atractylodis, Sanguis Draxonis, Herba Selaginellae, Lignum Sappan, Semen Coicis, Radix Pseudostellariae, Phymatopsis griffithiana (Hook.) J. Sm., Radix Sophorae Flavescentis, Borneolum Syntheticum, Flos Lonicerae, Herba Houttuyniae, Herba Hemisteptae Lyratae, Fructus Corni, Semen Cuscutae, Flos Celosiae Cristatae, Myrrha, Herba Polygoni Avicularis, Caulis Sargentodoxae and Radix et Herba Teucrii Quadrifari.

Wherein, in described medicine, the weight of each crude drug is respectively Fructus Cnidii 25g ~ 35g, Cortex Phellodendri 55g ~ 65g, Radix Et Caulis Acanthopanacis Senticosi 25g ~ 35g, Elephantopus scaber L. 30g ~ 40g, Fructus Toosendan 25g ~ 35g, Radix Polygoni Multiflori 30g ~ 40g, Radix Angelicae Dahuricae 25g ~ 35g, Rhizoma Atractylodis 15g ~ 25g, Sanguis Draxonis 15g ~ 25g, Herba Selaginellae 20g ~ 30g, Lignum Sappan 25g ~ 35g, Semen Coicis 20g ~ 30g, Radix Pseudostellariae 30g ~ 40g, Phymatopsis griffithiana (Hook.) J. Sm. 25g ~ 35g, Radix Sophorae Flavescentis 20g ~ 30g, Borneolum Syntheticum 20g ~ 30g, Flos Lonicerae 35g ~ 45g, Herba Houttuyniae 25g ~ 35g, Herba Hemisteptae Lyratae 20g ~ 30g, Fructus Corni 30g ~ 40g, Semen Cuscutae 25g ~ 35g, Flos Celosiae Cristatae 20g ~ 30g, Myrrha 25g ~ 35g, Herba Polygoni Avicularis 20g ~ 30g, Caulis Sargentodoxae 25g ~ 35g and Radix et Herba Teucrii Quadrifari 25g ~ 35g.

Wherein, in described medicine, the weight of each crude drug is respectively Fructus Cnidii 28g ~ 32g, Cortex Phellodendri 58g ~ 62g, Radix Et Caulis Acanthopanacis Senticosi 28g ~ 32g, Elephantopus scaber L. 33g ~ 37g, Fructus Toosendan 28g ~ 32g, Radix Polygoni Multiflori 33g ~ 37g, Radix Angelicae Dahuricae 28g ~ 32g, Rhizoma Atractylodis 18g ~ 22g, Sanguis Draxonis 18g ~ 22g, Herba Selaginellae 23g ~ 27g, Lignum Sappan 28g ~ 32g, Semen Coicis 23g ~ 27g, Radix Pseudostellariae 33g ~ 37g, Phymatopsis griffithiana (Hook.) J. Sm. 28g ~ 32g, Radix Sophorae Flavescentis 23g ~ 27g, Borneolum Syntheticum 23g ~ 27g, Flos Lonicerae 38g ~ 42g, Herba Houttuyniae 28g ~ 32g, Herba Hemisteptae Lyratae 23g ~ 27g, Fructus Corni 33g ~ 37g, Semen Cuscutae 28g ~ 32g, Flos Celosiae Cristatae 23g ~ 27g, Myrrha 28g ~ 32g, Herba Polygoni Avicularis 23g ~ 27g, Caulis Sargentodoxae 28g ~ 32g and Radix et Herba Teucrii Quadrifari 28g ~ 32g.

Wherein, in described medicine, the weight of each crude drug is respectively Fructus Cnidii 30g, Cortex Phellodendri 60g, Radix Et Caulis Acanthopanacis Senticosi 30g, Elephantopus scaber L. 35g, Fructus Toosendan 30g, Radix Polygoni Multiflori 35g, Radix Angelicae Dahuricae 30g, Rhizoma Atractylodis 20g, Sanguis Draxonis 20g, Herba Selaginellae 25g, Lignum Sappan 30g, Semen Coicis 25g, Radix Pseudostellariae 35g, Phymatopsis griffithiana (Hook.) J. Sm. 30g, Radix Sophorae Flavescentis 25g, Borneolum Syntheticum 25g, Flos Lonicerae 40g, Herba Houttuyniae 30g, Herba Hemisteptae Lyratae 25g, Fructus Corni 35g, Semen Cuscutae 30g, Flos Celosiae Cristatae 25g, Myrrha 30g, Herba Polygoni Avicularis 25g, Caulis Sargentodoxae 30g and Radix et Herba Teucrii Quadrifari 30g.

Wherein, described medicine is prepared into endo-medicine dosage form and liniment dosage form.

Wherein, described liniment dosage form is powder.

Wherein, described endo-medicine dosage form is soup decoct.

When described medicine is prepared into decoction liquor, its preparation method is specially:

Each crude drug is pulverized respectively, be mixed in proportion, obtain mixture, decoct with water 2 times, first time adds the water relative to mixture quality 8 ~ 10 times of quality, decoct 1 ~ 2 hour, filter, in filtering residue, again add the water relative to mixture quality 4 ~ 6 times of quality, decoct 1 ~ 2 hour, filter, the filtrate mixing twice filtration obtained, is concentrated into the solution of 1g/ml.

When described medicine is prepared into powder, its preparation method is specially:

The first step, by borneol and grinding powdered;

Second step, by remaining components by above-mentioned weight portion mixing, be placed in percolator, adding determining alcohol is in the ethanol of 85% ~ 95%, flood 24 hours ~ 36 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation subsequently, collect percolate, the quality of the ethanol added is 3 ~ 6 times of this mixture quality, be evaporated to about 1/10 of original volume, adopt centrifuge, obtain supernatant, subsequently, by supernatant hold over night at the temperature of 0 DEG C, filter, obtain the first extracting solution, the clear paste of relative density 1.05 ~ 1.15 is concentrated into 55 ~ 60 DEG C time with decompression concentrator, steam is selected to concentrate again, the thick paste of relative density 1.25 ~ 1.30 when clear paste steam is concentrated into 55 ~ 60 DEG C,

3rd step, the thick paste mix homogeneously that the powder obtain the first step and second step obtain, dry, flour powdered, crosses 200 mesh sieves, obtains powder.

Beneficial effect of the present invention:

The medicine being used for the treatment of chronic cervicitis provided by the invention can not only treat cervical erosion effectively, and obviously can alleviate the associated clinical symptoms such as waist bones of the body portion pain, abdominal part tenesmus, improves the life quality of patient, and safe and reliable, without obvious adverse reaction.

Detailed description of the invention

The invention provides a kind of medicine being used for the treatment of chronic cervicitis, its crude drug comprises Fructus Cnidii, Cortex Phellodendri, Radix Et Caulis Acanthopanacis Senticosi, Elephantopus scaber L., Fructus Toosendan, Radix Polygoni Multiflori, the Radix Angelicae Dahuricae, Rhizoma Atractylodis, Sanguis Draxonis, Herba Selaginellae, Lignum Sappan, Semen Coicis, Radix Pseudostellariae, Phymatopsis griffithiana (Hook.) J. Sm., Radix Sophorae Flavescentis, Borneolum Syntheticum, Flos Lonicerae, Herba Houttuyniae, Herba Hemisteptae Lyratae, Fructus Corni, Semen Cuscutae, Flos Celosiae Cristatae, Myrrha, Herba Polygoni Avicularis, Caulis Sargentodoxae and Radix et Herba Teucrii Quadrifari.

Further, described medicine is only made up of above-mentioned raw materials medicine.

In described medicine, the weight of each crude drug is respectively Fructus Cnidii 25g ~ 35g, Cortex Phellodendri 55g ~ 65g, Radix Et Caulis Acanthopanacis Senticosi 25g ~ 35g, Elephantopus scaber L. 30g ~ 40g, Fructus Toosendan 25g ~ 35g, Radix Polygoni Multiflori 30g ~ 40g, Radix Angelicae Dahuricae 25g ~ 35g, Rhizoma Atractylodis 15g ~ 25g, Sanguis Draxonis 15g ~ 25g, Herba Selaginellae 20g ~ 30g, Lignum Sappan 25g ~ 35g, Semen Coicis 20g ~ 30g, Radix Pseudostellariae 30g ~ 40g, Phymatopsis griffithiana (Hook.) J. Sm. 25g ~ 35g, Radix Sophorae Flavescentis 20g ~ 30g, Borneolum Syntheticum 20g ~ 30g, Flos Lonicerae 35g ~ 45g, Herba Houttuyniae 25g ~ 35g, Herba Hemisteptae Lyratae 20g ~ 30g, Fructus Corni 30g ~ 40g, Semen Cuscutae 25g ~ 35g, Flos Celosiae Cristatae 20g ~ 30g, Myrrha 25g ~ 35g, Herba Polygoni Avicularis 20g ~ 30g, Caulis Sargentodoxae 25g ~ 35g and Radix et Herba Teucrii Quadrifari 25g ~ 35g.

Further, in described medicine, the weight of each crude drug is respectively Fructus Cnidii 28g ~ 32g, Cortex Phellodendri 58g ~ 62g, Radix Et Caulis Acanthopanacis Senticosi 28g ~ 32g, Elephantopus scaber L. 33g ~ 37g, Fructus Toosendan 28g ~ 32g, Radix Polygoni Multiflori 33g ~ 37g, Radix Angelicae Dahuricae 28g ~ 32g, Rhizoma Atractylodis 18g ~ 22g, Sanguis Draxonis 18g ~ 22g, Herba Selaginellae 23g ~ 27g, Lignum Sappan 28g ~ 32g, Semen Coicis 23g ~ 27g, Radix Pseudostellariae 33g ~ 37g, Phymatopsis griffithiana (Hook.) J. Sm. 28g ~ 32g, Radix Sophorae Flavescentis 23g ~ 27g, Borneolum Syntheticum 23g ~ 27g, Flos Lonicerae 38g ~ 42g, Herba Houttuyniae 28g ~ 32g, Herba Hemisteptae Lyratae 23g ~ 27g, Fructus Corni 33g ~ 37g, Semen Cuscutae 28g ~ 32g, Flos Celosiae Cristatae 23g ~ 27g, Myrrha 28g ~ 32g, Herba Polygoni Avicularis 23g ~ 27g, Caulis Sargentodoxae 28g ~ 32g and Radix et Herba Teucrii Quadrifari 28g ~ 32g.

Most preferably, in described medicine, the weight of each crude drug is respectively Fructus Cnidii 30g, Cortex Phellodendri 60g, Radix Et Caulis Acanthopanacis Senticosi 30g, Elephantopus scaber L. 35g, Fructus Toosendan 30g, Radix Polygoni Multiflori 35g, Radix Angelicae Dahuricae 30g, Rhizoma Atractylodis 20g, Sanguis Draxonis 20g, Herba Selaginellae 25g, Lignum Sappan 30g, Semen Coicis 25g, Radix Pseudostellariae 35g, Phymatopsis griffithiana (Hook.) J. Sm. 30g, Radix Sophorae Flavescentis 25g, Borneolum Syntheticum 25g, Flos Lonicerae 40g, Herba Houttuyniae 30g, Herba Hemisteptae Lyratae 25g, Fructus Corni 35g, Semen Cuscutae 30g, Flos Celosiae Cristatae 25g, Myrrha 30g, Herba Polygoni Avicularis 25g, Caulis Sargentodoxae 30g and Radix et Herba Teucrii Quadrifari 30g.

Fructus Cnidii: latin name cnidiifructus, acrid in the mouth, hardship, warm in nature, enter kidney channel, have the effect of warming the kidney to invigorate YANG, removing dampness and killing parasites, dispelling wind for relieving itching, the impotence in male caused for kidney yang deficiency, woman's cold womb are infertile, the cards such as cold-damp leukorrhagia or chills and pain of the waist and kness.

Cortex Phellodendri: latin name PhellodendriChinensisCortex, bitter in the mouth, cold in nature, enter kidney, bladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, and seminal emission, sore swollen toxin, the cards such as eczema pruritus, Cortex Phellodendri has good antibacterial action to multiple gram-positive bacterium.

Radix Et Caulis Acanthopanacis Senticosi: be the root of studies on plants of Acanthopanax Miq. in Araliaceae Radix Et Caulis Acanthopanacis Senticosi, rhizome or stem and leaf, latin name AcanthopanacisSenticosiRadixetRhizomaseuCaulis, acrid in the mouth, hardship, micro-sweet, warm in nature, enter spleen, kidney, heart channel, there is replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, effect of expelling wind and removing dampness, soft for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity, be slow in action, the card such as body weakness with emaciation is weak, traumatic injury, fracture, edema, beriberi, uncontrolled urination are itched

Elephantopus scaber L.: cold in nature, bitter in the mouth is pungent, has heat-clearing and toxic substances removing, and effect of inducing diuresis to remove edema, cures mainly flu, acute tonsillitis, pharyngolaryngitis, eye conjunctivitis, epidemic encephalitis type B, pertussis, acute icterohepatitis, cirrhotic ascites, acute and chronic nephritis, furuncle and phyma, the cards such as eczema.

Fructus Toosendan: bitter in the mouth, cold in nature, returns liver, small intestinal, urinary bladder channel, have soothing the liverly to expel the heat-evil, effects of promoting the circulation of QI to relieve pain, cure mainly pathogenic fire derived from stagnation of liver-QI, the breast side of body, play the cards such as abdominal distention and pain, hernia pain, abdominal pain due to worm stagnation.

Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature, returns liver, kidney channel, has effect of nourishing the blood and yin, loosening bowel to relieve constipation, cures mainly blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body is empty; Rubella pruritus; Carbuncle sore; Scrofula; The cards such as hemorrhoid.

The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature, enter lung, spleen, stomach warp, there is the cold expelling that induces sweat, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, effect of detumescence and apocenosis, cures mainly headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, the cards such as scabies.

Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature, return spleen, stomach, Liver Channel, have drying damp and strengthening spleen, expelling wind and dampness, effect of improving eyesight, cure mainly the bellyache and diarrhea profit of retention of dampness in middle-JIAO; Incoordination between the spleen and stomach, to epigastric pain, is vomitted indigestion and loss of appetite; The distending pain in the chest and hypochondrium of incoordination between the liver and stomach, the cards such as vomiting with acid regurgitation.

Sanguis Draxonis: latin name DraconisSanguis, sweet in the mouth, salty, property is put down, and enters the heart, liver, spleen channel, has promoting blood circulation to remove blood stasis, effect of hemostasia and promoting granulation, for congestion amenorrhea, dysmenorrhea, postpartum stagnation, lump in the abdomen mass in the abdomen, breast ventral spine pain, traumatic injury, congestion swells and ache, traumatic hemorrhage, the cards such as ulcer being unable to heal.

Herba Selaginellae: latin name SelaginellaeHerba is the dry herb of Spikemoss plant Herba Selaginellae or Selaginella pulvinata: acrid in the mouth, property is put down, and returns liver, heart channel, has effect of promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, spit blood, metrorrhagia, has blood in stool, the cards such as proctoptosis.

Lignum Sappan: latin name sappanlignum, sweet in the mouth, salty, property is put down, and enters the heart, liver, large intestine channel, has blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain, for blood stasis amenorrhea, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, traumatic injury, the cards such as fracture carbuncle sore tumefacting virus.

Semen Coicis: latin name CoicisSemen, sweet in the mouth, light, cold nature, enters lung, spleen, large intestine channel, has invigorating the spleen to arrest diarrhea, diuretic eliminating impediment, and effect of row's skin ulcer pus, curing mainly having loose bowels of wet tired lung stomach; Damp invades the hydrosarca of stain skin, dysuria; The damp and hot numbness hindered in QI and blood passes to and the scorchingly hot card such as lung abscess, acute appendicitis pented up in lung intestinal.

Radix Pseudostellariae: sweet in the mouth, micro-hardship, property is put down, and enters spleen, lung meridian, has air making-up and spleen enlivening, the effect of the lung moistening and production of body fluid promoting, for the lack of appetite asthenia of deficiency-weakness of spleen-QI, deficiency of stomach-Yin, energy strengthening the spleen gas, nourishing stomach-YIN, for deficiency of the lung cough caused by dryness and cardiopalmus sleeplessness, the deficiency-heat hyperhidrosis of deficiency of vital energy Tianjin wound, energy supplementing QI for promoting the production of body fluid, controls deficiency of vital energy xeropulmonary cough, the card such as cardiopalmus sleeplessness, hyperhidrosis of deficiency of both QI and YIN.

Phymatopsis griffithiana (Hook.) J. Sm.: be the herb of Polypodiaceae pseudotumor Cyclosorus plant Phymatopsis integrifolia Ching, bitter in the mouth, cold in nature, enter spleen channel, have heat clearing away, removing heat from blood, removing toxic substances, treating stranguria effect, cures mainly carbuncle, toxic swelling, malignant boil, sudden and violent red acute catarrhal conjunctivitis, cough due to lung-heat, stranguria, the cards such as discharging fresh blood stool.

Radix Sophorae Flavescentis: bitter in the mouth, cold in nature, enter liver, kidney, large intestine, small intestinal, bladder, heart channel, have heat clearing and damp drying, effect of wind dispelling insecticide, cures mainly damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, the cards such as noxious dampness skin infection.

Borneolum Syntheticum: acrid in the mouth, hardship, cool in nature, GUIXIN, lung meridian, have refreshment of having one's ideas straightened out, and the loose poison of heat clearing away, the effect of improving acuity of vision and removing nebula, cures mainly apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, and hemorrhoid, order is nebula film also, the cards such as enterobiasis.

Flos Lonicerae: latin name loniceraejaponicaeflos, sweet in the mouth, cold in nature, enter the heart, lung, stomach, large intestine channel, have the effect of heat-clearing and toxic substances removing, holding concurrently can eliminating pathogenic heat from blood to cure dysentery.Be mainly used in affection due to external wind and heat, epidemic febrile disease pyretic toxicity is comparatively contained, or when epidemic febrile disease is still not descending at the part of the body cavity above the diaphragm housing the heart and lungs from the beginning of pathogenic heat; Pyretic toxicity dysentery, stool hematochezia; Fever disease in summer is demonstrate,proved.

Herba Houttuyniae: latin name houttuyniaeherba, acrid in the mouth, cold nature, enters lung, urinary bladder channel, has heat-clearing and toxic substances removing, removing pus and relieving carbuncle, effect of inducing diuresis for treating stranguria syndrome, and for lung abscess vomiting pus, expectorant heat syndrome cough is breathed heavily, toxic-heat and blood stasis, damp-heat gonorrhoea, pyretic toxicity carbuncle sore, and snakeworm wants first-class card.

Herba Hemisteptae Lyratae: be herb or the root of Compositae Herba Hemisteptae Lyratae platymiscium Herba Hemisteptae Lyratae, acrid in the mouth, hardship, cold in nature, have heat-clearing and toxic substances removing, effect of mass dissipating and swelling eliminating, cures mainly anal fistula, carbuncle furuncle, acute mastitis, lymphadenitis, rubella pruritus, traumatic hemorrhage, the cards such as fracture.

Fructus Corni: latin name cornifructus, sour in the mouth, puckery, slightly warm in nature, returns liver, kidney channel, has liver and kidney tonifying, effect of essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.Interior-heat such as to be quenched one's thirst at the card.

Semen Cuscutae: sweet in the mouth, pungent, property is put down, and enters liver,kidney,spleen warp, has the kidney invigorating and essence nourishing, the effect of nourishing the liver to improve visual acuity, be mainly used in the sexual impotence of insufficiency of kidney-YANG, seminal emission premature ejaculation, frequent micturition, dizziness and tinnitus; To suffer from a deficiency of the kidney pain in the lumbar region, married woman's leukorrhagia, nausea is solid; The binocular of both liver and kidney deficiency, deficiency of liver-blood is dim-sighted, blurring of vision; The loose stool stomachache of asthenia of both the spleen and kidney, the symptoms such as aqueous-grainy diarrhea.

Flos Celosiae Cristatae: sweet in the mouth, puckery, cool in nature, returns liver, large intestine channel, has astringing to arrest bleeding, effect of leukorrhagia stopping dysentery relieving, and for spitting blood, metrorrhagia, has blood in stool, hemorrhoidal bleeding, leucorrhea with red and white discharge, and chronic dysentery waits card incessantly.

Myrrha: latin name Myrrha, bitter in the mouth, pungent, property is put down, and enters liver, spleen, the heart, kidney channel, has effect of promoting blood circulation and stopping pain, detumescence and promoting granulation, cure mainly the cards such as breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.

Herba Polygoni Avicularis: latin name PolygoniAvicularisHerba, bitter in the mouth, cold nature, enters urinary bladder channel, has relieving stranguria by diuresis, effect of killing parasites for relieving itching, and for stranguria, especially sand Stranguria, stranguria caused by urinary stone, dysuria, jaundice due to damp-heat, dysentery, is with inferior card.

Caulis Sargentodoxae: latin name SargentodoxaeCaulis, bitter in the mouth, property is put down, and returns liver, large intestine channel, has the eliminating carbuncle that relieves internal heat, promoting blood circulation to remove obstruction in the collateral, the effect of wind dispelling insecticide, cures mainly acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, the cards such as injury from falling down.

Radix et Herba Teucrii Quadrifari: be the herb of Labiatae Teucrium plant Radix et Herba Teucrii Quadrifari, root or leaf, acrid in the mouth, hardship, cool in nature, there is the expelling summer-heat that dispels the wind, inducing diuresis and reducing edema, effect of removing pathogenic heat from blood and toxic substance from the body, cures mainly anemopyretic cold, and heatstroke is lossless, cough due to lung-heat, lung abscess, pyretic toxicity dysentery, edema, rheumatalgia, spits blood, has blood in stool, acute mastitis, innominate toxic swelling, rubella, eczema, traumatic injury, traumatic hemorrhage, the cards such as venom.

Medicine provided by the invention is prepared into endo-medicine dosage form and liniment dosage form, liniment dosage form is powder, endo-medicine dosage form is soup decoct, by inside and outside drug combination, effectively can not only treat cervical erosion, and obviously can alleviate the associated clinical symptoms such as waist bones of the body portion pain, abdominal part tenesmus, improve the life quality of patient, and safe and reliable, without obvious adverse reaction, therefore, clinic is applied.、

The first step, by borneol and grinding powdered;

In addition, microwave is novel physiotherapy, expansible blood vessel, blood circulation promoting, improves the regeneration capacity of cell, strengthens lymphocytic immunologic function, improve leukocytic phagocytic function, promote the healing in rotten to the corn face, adopt treatment of chronic cervicitis by microwave, there is required instrument volume little, portable, easy to operate, have no irritating odor in art, smoke dust, is directly contacted with tissue by probe, directed accurately, the not easily advantage such as damaging surrounding tissue.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1 soup decoct 1

By Fructus Cnidii 30g, Cortex Phellodendri 60g, Radix Et Caulis Acanthopanacis Senticosi 30g, Elephantopus scaber L. 35g, Fructus Toosendan 30g, Radix Polygoni Multiflori 35g, Radix Angelicae Dahuricae 30g, Rhizoma Atractylodis 20g, Sanguis Draxonis 20g, Herba Selaginellae 25g, Lignum Sappan 30g, Semen Coicis 25g, Radix Pseudostellariae 35g, Phymatopsis griffithiana (Hook.) J. Sm. 30g, Radix Sophorae Flavescentis 25g, Borneolum Syntheticum 25g, Flos Lonicerae 40g, Herba Houttuyniae 30g, Herba Hemisteptae Lyratae 25g, Fructus Corni 35g, Semen Cuscutae 30g, Flos Celosiae Cristatae 25g, Myrrha 30g, Herba Polygoni Avicularis 25g, Caulis Sargentodoxae 30g and Radix et Herba Teucrii Quadrifari 30g pulverizes respectively, mixing, obtain mixture, decoct with water 2 times, add the water of 7kg for the first time, decoct 2 hours, filter, the water of relative 4kg is again added in filtering residue, decoct 2 hours, filter, the filtrate mixing that twice filtration is obtained, be concentrated into the solution of 1g/ml, obtain soup decoct 1.

Embodiment 2 soup decoct 2

By Fructus Cnidii 28g, Cortex Phellodendri 58g, Radix Et Caulis Acanthopanacis Senticosi 28g, Elephantopus scaber L. 33g, Fructus Toosendan 28g, Radix Polygoni Multiflori 33g, Radix Angelicae Dahuricae 28g, Rhizoma Atractylodis 18g, Sanguis Draxonis 18g, Herba Selaginellae 23g, Lignum Sappan 28g, Semen Coicis 23g, Radix Pseudostellariae 33g, Phymatopsis griffithiana (Hook.) J. Sm. 28g, Radix Sophorae Flavescentis 23g, Borneolum Syntheticum 23g, Flos Lonicerae 38g, Herba Houttuyniae 28g, Herba Hemisteptae Lyratae 23g, Fructus Corni 33g, Semen Cuscutae 28g, Flos Celosiae Cristatae 23g, Myrrha 28g, Herba Polygoni Avicularis 23g, Caulis Sargentodoxae 28g and Radix et Herba Teucrii Quadrifari 28g pulverizes respectively, mixing, obtain mixture, decoct with water 2 times, add the water of 7kg for the first time, decoct 2 hours, filter, the water of relative 4kg is again added in filtering residue, decoct 2 hours, filter, the filtrate mixing that twice filtration is obtained, be concentrated into the solution of 1g/ml, obtain soup decoct 2.

Embodiment 3 soup decoct 3

By Fructus Cnidii 32g, Cortex Phellodendri 62g, Radix Et Caulis Acanthopanacis Senticosi 32g, Elephantopus scaber L. 37g, Fructus Toosendan 32g, Radix Polygoni Multiflori 37g, Radix Angelicae Dahuricae 32g, Rhizoma Atractylodis 22g, Sanguis Draxonis 22g, Herba Selaginellae 27g, Lignum Sappan 32g, Semen Coicis 27g, Radix Pseudostellariae 37g, Phymatopsis griffithiana (Hook.) J. Sm. 32g, Radix Sophorae Flavescentis 27g, Borneolum Syntheticum 27g, Flos Lonicerae 42g, Herba Houttuyniae 32g, Herba Hemisteptae Lyratae 27g, Fructus Corni 37g, Semen Cuscutae 32g, Flos Celosiae Cristatae 27g, Myrrha 32g, Herba Polygoni Avicularis 27g, Caulis Sargentodoxae 32g and Radix et Herba Teucrii Quadrifari 32g pulverizes respectively, mixing, obtain mixture, decoct with water 2 times, add the water of 7kg for the first time, decoct 2 hours, filter, the water of relative 4kg is again added in filtering residue, decoct 2 hours, filter, the filtrate mixing that twice filtration is obtained, be concentrated into the solution of 1g/ml, obtain soup decoct 3.

Embodiment 4 powder 1

By 25g borneol and grinding powdered, by Fructus Cnidii 30g, Cortex Phellodendri 60g, Radix Et Caulis Acanthopanacis Senticosi 30g, Elephantopus scaber L. 35g, Fructus Toosendan 30g, Radix Polygoni Multiflori 35g, Radix Angelicae Dahuricae 30g, Rhizoma Atractylodis 20g, Sanguis Draxonis 20g, Herba Selaginellae 25g, Lignum Sappan 30g, Semen Coicis 25g, Radix Pseudostellariae 35g, Phymatopsis griffithiana (Hook.) J. Sm. 30g, Radix Sophorae Flavescentis 25g, Flos Lonicerae 40g, Herba Houttuyniae 30g, Herba Hemisteptae Lyratae 25g, Fructus Corni 35g, Semen Cuscutae 30g, Flos Celosiae Cristatae 25g, Myrrha 30g, Herba Polygoni Avicularis 25g, Caulis Sargentodoxae 30g and Radix et Herba Teucrii Quadrifari 30g mixes, be placed in percolator, adding determining alcohol is in the ethanol 4kg of 95%, flood 24 hours, adopt percolation with the speed of 2ml per minute slowly percolation subsequently, collect percolate, be evaporated to about 1/10 of original volume, adopt centrifuge, obtain supernatant, subsequently, by supernatant hold over night at the temperature of 0 DEG C, filter, obtain the first extracting solution, be concentrated into the clear paste of relative density 1.15 with decompression concentrator 60 DEG C time, then select steam to concentrate, the thick paste of relative density 1.30 when clear paste steam is concentrated into 60 DEG C, by the borneol powder that obtains and thick paste mix homogeneously, dry, flour powdered, cross 200 mesh sieves, obtain powder 1.

Embodiment 5 powder 2

By 23g borneol and grinding powdered, by Fructus Cnidii 28g, Cortex Phellodendri 58g, Radix Et Caulis Acanthopanacis Senticosi 28g, Elephantopus scaber L. 33g, Fructus Toosendan 28g, Radix Polygoni Multiflori 33g, Radix Angelicae Dahuricae 28g, Rhizoma Atractylodis 18g, Sanguis Draxonis 18g, Herba Selaginellae 23g, Lignum Sappan 28g, Semen Coicis 23g, Radix Pseudostellariae 33g, Phymatopsis griffithiana (Hook.) J. Sm. 28g, Radix Sophorae Flavescentis 23g, Flos Lonicerae 38g, Herba Houttuyniae 28g, Herba Hemisteptae Lyratae 23g, Fructus Corni 33g, Semen Cuscutae 28g, Flos Celosiae Cristatae 23g, Myrrha 28g, Herba Polygoni Avicularis 23g, Caulis Sargentodoxae 28g and Radix et Herba Teucrii Quadrifari 28g mixes, be placed in percolator, adding determining alcohol is in the ethanol 4kg of 95%, flood 24 hours, adopt percolation with the speed of 2ml per minute slowly percolation subsequently, collect percolate, be evaporated to about 1/10 of original volume, adopt centrifuge, obtain supernatant, subsequently, by supernatant hold over night at the temperature of 0 DEG C, filter, obtain the first extracting solution, be concentrated into the clear paste of relative density 1.15 with decompression concentrator 60 DEG C time, then select steam to concentrate, the thick paste of relative density 1.30 when clear paste steam is concentrated into 60 DEG C, by the borneol powder that obtains and thick paste mix homogeneously, dry, flour powdered, cross 200 mesh sieves, obtain powder 2.

Embodiment 6 powder 3

By 27g borneol and grinding powdered, by Fructus Cnidii 32g, Cortex Phellodendri 62g, Radix Et Caulis Acanthopanacis Senticosi 32g, Elephantopus scaber L. 37g, Fructus Toosendan 32g, Radix Polygoni Multiflori 37g, Radix Angelicae Dahuricae 32g, Rhizoma Atractylodis 22g, Sanguis Draxonis 22g, Herba Selaginellae 27g, Lignum Sappan 32g, Semen Coicis 27g, Radix Pseudostellariae 37g, Phymatopsis griffithiana (Hook.) J. Sm. 32g, Radix Sophorae Flavescentis 27g, Flos Lonicerae 42g, Herba Houttuyniae 32g, Herba Hemisteptae Lyratae 27g, Fructus Corni 37g, Semen Cuscutae 32g, Flos Celosiae Cristatae 27g, Myrrha 32g, Herba Polygoni Avicularis 27g, Caulis Sargentodoxae 32g and Radix et Herba Teucrii Quadrifari 32g mixes, be placed in percolator, adding determining alcohol is in the ethanol 5kg of 95%, flood 24 hours, adopt percolation with the speed of 2ml per minute slowly percolation subsequently, collect percolate, be evaporated to about 1/10 of original volume, adopt centrifuge, obtain supernatant, subsequently, by supernatant hold over night at the temperature of 0 DEG C, filter, obtain the first extracting solution, be concentrated into the clear paste of relative density 1.15 with decompression concentrator 60 DEG C time, then select steam to concentrate, the thick paste of relative density 1.30 when clear paste steam is concentrated into 60 DEG C, by the borneol powder that obtains and thick paste mix homogeneously, dry, flour powdered, cross 200 mesh sieves, obtain powder 3.

Embodiment 7 toxicological experiment

Acute toxicity testing

Select Kunming mouse 20, female half and half, body weight (20 +2) the soup decoct 1 of point 2 gavage embodiment 1 preparations in g, 12h, each gavage 1.0ml//20g, to observation post administration 7d, record animal dead and toxicity symptom, at the end of experiment, by all animals process, dissect, perusal each main organs lesion tissue situation, after gavaging, animal activity, feed water inlet does not show any abnormalities, and observe 7d animal dead, gross necropsy has no the obvious exception of main organs tissue.

Long term toxicity test

Select 40 male SD rats, weight (180 ± 20) g, be divided into 2 groups at random, blank group and Chinese drug-treated group, often organize 20, blank group gives distilled water, on every Mondays to soup decoct 1 prepared by gastric infusion in morning Saturday 1 embodiment 1, continuous 180d, administration volume is 2ml/100g body weight, and every day observes rat general state, sign, food ration, drinking-water and feces situation before administration and during administration.During administration 90d after last administration 24h, the extraction 6 of each group, male and female half and half; During 180d after last administration 24h, the extraction 6 of each group, male and female half and half; After drug withdrawal, 30d respectively organizes extraction 6, male and female half and half, anaesthetize with urethane, blood is got from abdominal aortic, each group is all killed and gets animal, checks hematology and blood parameters, after getting blood, amass wealth by heavy taxation at once core, liver,kidney,spleen, lung, adrenal gland, thyroid, thymus, testis, ovary, uterus, brain, the internal organs such as prostate weigh, and make pathological examination according to weight calculator official weight coefficient.

On inspection, during successive administration, the activity of animal, body weight, food ration, stool and hair luster degree no abnormality seen, animal has no dead, naked eyes have no obvious pathological changes, each group of rat peripheral hemogram checking is all in normal range, and the raw tea index of blood is all in normal range, and Chinese drug-treated group Rats Organs and Tissues coefficient does not have significant difference compared with blank group.

Irritation test

By healthy adult white, man exempts from 4, body weight 2.5 ~ 2.7kg, male and female half and half.By its spinal column both sides skin unhairing 3cm × 3cm, powder 1 prepared by Example 1 is dissolved in water, 2.5cm × 2.5cm bis-layers of gauze are immersed in 10min in this dispersant solution, be applied on a plucked skin in rabbit back side subsequently, cover with one deck cellophane, fixed with nonirritant medical proof fabric and binder, opposite side distilled water compares again.Every experimental animal is applied ointment or plaster after 4h, removes tested material, with the skin of warm water cleaning application site, respectively at 1,24,48h observes and records the dermoreaction of application site, the standards of grading specified according to " disinfection technology standard " and classification are marked.Irritation test shows, Chinese powder medicine provided by the invention 1 pair of rabbit skin wound repair integration is 0, and skin, without erythema, belongs to non-stimulated.

Embodiment 8 clinical data

Physical data

Select virus in patients with cervicitis 170 example that 2011 in JIUYUE, 2 to 2013 are diagnosed at Out-patient Clinic of Department of Gynecology, according to the diagnostic criteria of " obstetrics and gynecology " the 7th edition.Cervicitis is defined as II ~ III degree, and is mastoid process type, granular pattern; Patient is and marriedly educates.Preoperative through gynecologial examination, leucorrhea is conventional, cervical scraping smear cytolgical examination and colposcopy, gets rid of acute inflammation and cervicitis.Be divided into two groups at random, experimental group 85 example, matched group 85 example.Two groups of mean aves, pregnant time, parity, cervicitis classification comparing difference not statistically significant (P > 0.05), have comparability.

Method

The treatment date selects clean period 2 ~ 7d to carry out.Microwave apparatus (YWY-2A) is produced by Nanjing Kang You microwave applications institute, selects power 40 ~ 50W.Two groups of patients all adopt microwave Vertical Uniform to burn pathological tissues, and make the rapid carbonization of pathological tissues become crust, scope crosses focus edge about 2mm.The powder 1 that embodiment 4 is prepared before sleeping the 2nd day evening by experimental group 85 example loads in sterile glass container for subsequent use, the front dry cotton ball of the drug of topical application is by cervical surface secretions wiped clean, and according to rotten to the corn face size, after dipping appropriate powder with band wire cotton balls, powder spreads on rotten to the corn face, avoid being coated on the healthy film that slits and cause damage, 24h takes out cotton balls, treats 1 time daily evening before sleep, simultaneously, soup decoct 1 prepared by oral embodiment 1, every day 2 times, take before early sleeping in 1h and evening before the meal, continuous 3 weeks.Matched group oral azithromycin postoperative every day 1 time, 0.5g/ time, and insert 0.25g clarithromycin in vagina deep uterus neck before sleeping every day.

Curative effect judging standard

Cure: cervix uteri is smooth, rotten to the corn face disappears, the whole squama of epithelium of cervix uteri; Effective: rotten to the corn area reduces > 50%; Invalid: rotten to the corn area is unchanged; Outpatient service follow-up observation in February after all operation in patients.Effectively total=to cure+effectively.

Statistical procedures

Measurement data adopts ± s represents, compares and adopt χ between group ²inspection, all data all adopt the process of SPSS17.0 statistical software.

Result

Two groups of neoplasm amounts and bleeding time compare, and the results are shown in Table 1.

Table 1 liang group neoplasm amount and bleeding time compare (unit: example)

Two groups of therapeutic effect compare, and the results are shown in Table 2.

A table 2 liang group therapeutic effect compares (unit: example)

Group	Number of cases	Cure	Effectively	Invalid	Total effective rate
						Experimental group	85	76	8	1	98.8%
Matched group	85	42	34	9	89.4%

As can be seen from the result of table 1 and table 2, significantly better than matched group patient in the patient's curative effect adopting Drug therapy provided by the invention.

All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims

1. be used for the treatment of a medicine for chronic cervicitis, it is characterized in that: crude drug comprises Fructus Cnidii, Cortex Phellodendri, Radix Et Caulis Acanthopanacis Senticosi, Elephantopus scaber L., Fructus Toosendan, Radix Polygoni Multiflori, the Radix Angelicae Dahuricae, Rhizoma Atractylodis, Sanguis Draxonis, Herba Selaginellae, Lignum Sappan, Semen Coicis, Radix Pseudostellariae, Phymatopsis griffithiana (Hook.) J. Sm., Radix Sophorae Flavescentis, Borneolum Syntheticum, Flos Lonicerae, Herba Houttuyniae, Herba Hemisteptae Lyratae, Fructus Corni, Semen Cuscutae, Flos Celosiae Cristatae, Myrrha, Herba Polygoni Avicularis, Caulis Sargentodoxae and Radix et Herba Teucrii Quadrifari.

2. be used for the treatment of the medicine of chronic cervicitis as claimed in claim 1, it is characterized in that: the weight of each crude drug is respectively Fructus Cnidii 25g ~ 35g, Cortex Phellodendri 55g ~ 65g, Radix Et Caulis Acanthopanacis Senticosi 25g ~ 35g, Elephantopus scaber L. 30g ~ 40g, Fructus Toosendan 25g ~ 35g, Radix Polygoni Multiflori 30g ~ 40g, Radix Angelicae Dahuricae 25g ~ 35g, Rhizoma Atractylodis 15g ~ 25g, Sanguis Draxonis 15g ~ 25g, Herba Selaginellae 20g ~ 30g, Lignum Sappan 25g ~ 35g, Semen Coicis 20g ~ 30g, Radix Pseudostellariae 30g ~ 40g, Phymatopsis griffithiana (Hook.) J. Sm. 25g ~ 35g, Radix Sophorae Flavescentis 20g ~ 30g, Borneolum Syntheticum 20g ~ 30g, Flos Lonicerae 35g ~ 45g, Herba Houttuyniae 25g ~ 35g, Herba Hemisteptae Lyratae 20g ~ 30g, Fructus Corni 30g ~ 40g, Semen Cuscutae 25g ~ 35g, Flos Celosiae Cristatae 20g ~ 30g, Myrrha 25g ~ 35g, Herba Polygoni Avicularis 20g ~ 30g, Caulis Sargentodoxae 25g ~ 35g and Radix et Herba Teucrii Quadrifari 25g ~ 35g.

3. be used for the treatment of the medicine of chronic cervicitis as claimed in claim 1 or 2, it is characterized in that: the weight of each crude drug is respectively Fructus Cnidii 28g ~ 32g, Cortex Phellodendri 58g ~ 62g, Radix Et Caulis Acanthopanacis Senticosi 28g ~ 32g, Elephantopus scaber L. 33g ~ 37g, Fructus Toosendan 28g ~ 32g, Radix Polygoni Multiflori 33g ~ 37g, Radix Angelicae Dahuricae 28g ~ 32g, Rhizoma Atractylodis 18g ~ 22g, Sanguis Draxonis 18g ~ 22g, Herba Selaginellae 23g ~ 27g, Lignum Sappan 28g ~ 32g, Semen Coicis 23g ~ 27g, Radix Pseudostellariae 33g ~ 37g, Phymatopsis griffithiana (Hook.) J. Sm. 28g ~ 32g, Radix Sophorae Flavescentis 23g ~ 27g, Borneolum Syntheticum 23g ~ 27g, Flos Lonicerae 38g ~ 42g, Herba Houttuyniae 28g ~ 32g, Herba Hemisteptae Lyratae 23g ~ 27g, Fructus Corni 33g ~ 37g, Semen Cuscutae 28g ~ 32g, Flos Celosiae Cristatae 23g ~ 27g, Myrrha 28g ~ 32g, Herba Polygoni Avicularis 23g ~ 27g, Caulis Sargentodoxae 28g ~ 32g and Radix et Herba Teucrii Quadrifari 28g ~ 32g.

4. the medicine being used for the treatment of chronic cervicitis as described in claims 1 to 3, is characterized in that: the weight of each crude drug is respectively Fructus Cnidii 30g, Cortex Phellodendri 60g, Radix Et Caulis Acanthopanacis Senticosi 30g, Elephantopus scaber L. 35g, Fructus Toosendan 30g, Radix Polygoni Multiflori 35g, Radix Angelicae Dahuricae 30g, Rhizoma Atractylodis 20g, Sanguis Draxonis 20g, Herba Selaginellae 25g, Lignum Sappan 30g, Semen Coicis 25g, Radix Pseudostellariae 35g, Phymatopsis griffithiana (Hook.) J. Sm. 30g, Radix Sophorae Flavescentis 25g, Borneolum Syntheticum 25g, Flos Lonicerae 40g, Herba Houttuyniae 30g, Herba Hemisteptae Lyratae 25g, Fructus Corni 35g, Semen Cuscutae 30g, Flos Celosiae Cristatae 25g, Myrrha 30g, Herba Polygoni Avicularis 25g, Caulis Sargentodoxae 30g and Radix et Herba Teucrii Quadrifari 30g.

5. the medicine being used for the treatment of chronic cervicitis as described in Claims 1-4, is characterized in that: described medicine is prepared into endo-medicine dosage form and liniment dosage form.

6. the medicine being used for the treatment of chronic cervicitis as described in claim 1 to 5, is characterized in that: described liniment dosage form is powder.

7. the medicine being used for the treatment of chronic cervicitis as described in claim 1 to 6, is characterized in that: described endo-medicine dosage form is soup decoct.

8. the preparation method being used for the treatment of the medicine of chronic cervicitis described in claim 1 to 7, is characterized in that:

When described medicine is prepared into decoction liquor, is specially and each crude drug is pulverized respectively, be mixed in proportion, obtain mixture, decoct with water 2 times, first time adds the water relative to mixture quality 8 ~ 10 times of quality, decocts 1 ~ 2 hour, filter, in filtering residue, again add the water relative to mixture quality 4 ~ 6 times of quality, decoct 1 ~ 2 hour, filter, the filtrate mixing twice filtration obtained, is concentrated into the solution of 1g/ml.

9. the preparation method being used for the treatment of the medicine of chronic cervicitis described in claim 1 to 7, is characterized in that: when described medicine is prepared into powder, be specially,

The first step, by borneol and grinding powdered;