CN104288518A - Traditional Chinese medicine composition for treating cervicitis - Google Patents

Traditional Chinese medicine composition for treating cervicitis Download PDF

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Publication number
CN104288518A
CN104288518A CN201410582115.6A CN201410582115A CN104288518A CN 104288518 A CN104288518 A CN 104288518A CN 201410582115 A CN201410582115 A CN 201410582115A CN 104288518 A CN104288518 A CN 104288518A
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China
Prior art keywords
parts
fructus
radix
herba
cervicitis
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张萍
史光军
刘萍
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Qingdao Municipal Hospital
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Qingdao Municipal Hospital
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Abstract

The invention relates to the field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine composition for treating cervicitis. The traditional Chinese medicine composition for treating cervicitis comprises the following components: frankincense, schisandra chinensis, fructus cnidii, dried alum, compound of glauber-salt and liquorice, cutch, radix sophorae flavescentis, fructus malvae vertillatae, plantain herb, angelica sinensis, liquorice, root and rhizome of iris speculatrix, shiny-leaved yellowhorn, plum blossom, jamaica falsevalerian herb, common andrographis herb, trichosanthes kirilowii maxim, selfheal, folium artemisiae argyi, sargentgloryvine stem, rhizoma acori graminei, rhizoma bletillae, dragon's blood, dioscorea panthaica, Chinese wolfberries, herba corydalis bungeanae, fructus evodiae, stichopus japonicus and radix bupleuri. The traditional Chinese medicine composition for treating cervicitis has the efficacies of clearing away heat and toxic materials, sterilization and relieving itching; the curative effect on cervicitis is excellent.

Description

A kind of Chinese medicine composition for the treatment of cervicitis
Technical field
The invention belongs to technical field of traditional Chinese pharmacology, be specifically related to a kind of Chinese medicine composition for the treatment of cervicitis.
Background technology
Cervicitis is gynecological's common disease, and sickness rate increases just year by year in recent years, and cervicitis serious threat is to women's health.The understanding cardinal symptom of cervicitis, pathogenic factor, harm and preventive measure is inquired into from life and medical angle.More common with chronic cervicitis clinically, how to be changed by acute cervicitis.Childbirth, miscarriage or surgical injury cervix uteri, pathogen invades cervical mucosal.And hide herein. because cervical mucosal pleat is many, infect and not easily thoroughly remove, often become chronic cervicitis.In addition, chronic cervicitis and sexual life overfrequency, physics or chemical stimulation, endometritis, vaginitis are also relevant.The morbidity of cervical cancer and chronic cervicitis have certain relation, and the cervical cancer incidence rate having cervical erosion is 0.75%, is significantly higher than without cervical erosion person.Therefore, active treatment cervicitis is to the generation important in inhibiting of prevention cervical cancer.
Cervicitis main clinic symptoms, acute cervicitis cardinal symptom is leucorrhoea grow in quantity, in purulence, other symptom has lumbago and backache, pelvic cavity bearing down and frequent micturition, urgent micturition.Some patients has dyspareunia.And chronic cervicitis cardinal symptom is leucorrhoea grow in quantity.Because pathogen is different, leucorrhea amount, matter, color and abnormal smells from the patient are also different, and be creamy white mucus shape more, are faint yellow in purulence sometimes, easily have sanguinous leukorrhea or postcoital bleeding during companion's polyp.When inflammation is diffused into pelvic cavity along uterosacral ligament, there is waist and sacrum pain, pelvic cavity tenesmus pain etc.The leucorrhoea grow in quantity caused because of inflammation, sticky, in purulence, be unfavorable for that sperm is by cervical canal, and cause infertile.Cause the reason of cervicitis mainly in daily life.Some women have life-time service protective pad, long-time sitting motionless, blindly use the living habit such as vaginal lotion.Expert represents that these customs often make the cervix uteri of women be subject to antibacterial and invade and harass. and then cause various gynaecopathia.There are many women all to think, use protective pad that pudendum can be avoided to contact with the direct of underwear, contribute to keeping pudendum clean environment.This idea is very wrong, because life-time service protective pad, easily makes pudendum breathe freely bad and cause infection.So, recommend preferably only in menstruation, near for clean or menstruation to be used protective pad in a short time.In addition, long-time sitting is motionless, and custom sitting can cause blood circulation very not unimpeded, and the more important thing is, women's federation's pudendum of long-time sitting is breathed freely bad, and blood circulation is obstructed, and also occurs to infect cervicitis than being easier to.The cervicitis that excessive cleaning vagina causes, a lot of women when feeling that pudendum is uncomfortable, usually all can arrive pharmacy buy vaginal lotion return use.In fact. frequently use vaginal lotion, very large destruction can be caused to intravaginal environment, cause colpitic increasing the weight of on the contrary.
Chronic cervicitis often shows as uterine erosion, uterine glands cyst, and also secondary can cause urinary tract infection, patient often occurs infertile.Chronic cervicitis harm is a lot, once suffer from this disease, easily repeatedly, the more difficult radical cure of disease, therefore preventive measure is imperative for the state of an illness.
Can various diseases be caused when cervicitis is serious:
One, cervical cancer is caused: if virus in patients with cervicitis, not being controlled effectively, is likely cause canceration, if cervicitis canceration, so financial burden of inherently making patients when treatment, so it is wonderful that this situation had better not be allowed to occur as.
Two, the quality of sexual life is affected: the women suffering from cervicitis can feel special pain in sexual life, so naturally will rejection live, present man and wife compares the quality focusing on sexual life, in the event of above-mentioned situation, directly can cause the unhappy of sex partner, what send out therefrom is exactly the harmony of family.
Three, cervicitis can cause infertile: if chronic cervicitis is not treated, female acyesis can be caused, the shape of many women's acute cervicitis diseases is unconspicuous, general often out in the cold, thus cause the generation of chronic cervicitis, suffer from the women of cervicitis, can because sperm cannot arrive uterus by cervix uteri, thus can produce infertile.
Chronic cervicitis can affect pregnancy, when cervicitis occurring especially moderate, severe cervical are scorching, affect women and becomes pregnant, cause infertility, even cause miscarrying or fetal anomaly.
At present, the Western medicine for the treatment of cervicitis is a lot, but most drug therapeutic effect is poor, and treats into the shortcomings such as high, side effect is large in addition, even affects patient health time serious.In addition, also have the Chinese medicine of a lot for the treatment of cervicitis, but great majority have the shortcomings such as the low and treatment cycle of therapeutic effect difference, cure rate is long.
Summary of the invention
In order to solve the problems of the technologies described above, the technical solution used in the present invention is as follows: a kind of Chinese medicine composition for the treatment of cervicitis, be made up of each component of following parts by weight: Olibanum 10-50 part, Fructus Schisandrae Chinensis 10-50 part, Fructus Cnidii 5-40 part, dried Alumen 5-40 part, Matrii Sulfas Exsiccatus 10-60 part, catechu 10-30 part, Radix Sophorae Flavescentis 10-50 part, Fructus Malvae 10-50 part, Herba Plantaginis 20-60 part, Radix Angelicae Sinensis 20-45 part, Radix Glycyrrhizae 10-30 part, Iris speculatrix Hance 10-60 part, Lignum Xanthoceratis 10-30 part, Flos Mume 15-45 part, Herba Stachytarphetae Jamaicensis 10-50 part, Herba Andrographis 10-40 part, Fructus Trichosanthis 10-30 part, Spica Prunellae 10-40 part, Folium Artemisiae Argyi 10-60 part, Caulis Sargentodoxae 10-25 part, Rhizoma Acori Graminei 10-45 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-50 part, Sanguis Draxonis 10-30 part, Dioscorea panthaica Prain et Burkill 10-60 part, Fructus Lycii 10-45 part, Herba Corydalis Bungeanae 10-35 part, Fructus Evodiae 10-60 part, Radix Morinae Bulleyanae 5-10 part, Radix Bupleuri 5-60 part.
Further, the present invention can be made up of each component of following parts by weight: Olibanum 20-50 part, Fructus Schisandrae Chinensis 15-50 part, Fructus Cnidii 10-40 part, dried Alumen 10-40 part, Matrii Sulfas Exsiccatus 15-60 part, catechu 15-30 part, Radix Sophorae Flavescentis 20-50 part, Fructus Malvae 20-50 part, Herba Plantaginis 25-60 part, Radix Angelicae Sinensis 30-45 part, Radix Glycyrrhizae 15-30 part, Iris speculatrix Hance 20-60 part, Lignum Xanthoceratis 15-30 part, Flos Mume 20-45 part, Herba Stachytarphetae Jamaicensis 15-50 part, Herba Andrographis 15-40 part, Fructus Trichosanthis 15-30 part, Spica Prunellae 15-40 part, Folium Artemisiae Argyi 20-60 part, Caulis Sargentodoxae 15-25 part, Rhizoma Acori Graminei 20-45 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-50 part, Sanguis Draxonis 15-30 part, Dioscorea panthaica Prain et Burkill 20-60 part, Fructus Lycii 20-45 part, Herba Corydalis Bungeanae 15-35 part, Fructus Evodiae 16-60 part, Radix Morinae Bulleyanae 8-10 part, Radix Bupleuri 10-60 part.
Further, the present invention can be made up of each component of following parts by weight: Olibanum 30 parts, Fructus Schisandrae Chinensis 25 parts, Fructus Cnidii 15 parts, dried Alumen 15 parts, Matrii Sulfas Exsiccatus 15 parts, 25 parts, catechu, Radix Sophorae Flavescentis 25 parts, Fructus Malvae 30 parts, Herba Plantaginis 25 parts, Radix Angelicae Sinensis 30 parts, 15 parts, Radix Glycyrrhizae, Iris speculatrix Hance 30 parts, Lignum Xanthoceratis 20 parts, 30 parts, Flos Mume, Herba Stachytarphetae Jamaicensis 20 parts, Herba Andrographis 30 parts, Fructus Trichosanthis 30 parts, Spica Prunellae 15 parts, Folium Artemisiae Argyi 20 parts, Caulis Sargentodoxae 25 parts, Rhizoma Acori Graminei 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Sanguis Draxonis 30 parts, Dioscorea panthaica Prain et Burkill 40 parts, Fructus Lycii 25 parts, Herba Corydalis Bungeanae 20 parts, Fructus Evodiae 30 parts, Radix Morinae Bulleyanae 8 parts, Radix Bupleuri 20 parts.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition, comprise the following steps:
The first step, Olibanum, Fructus Schisandrae Chinensis, Fructus Cnidii, dried Alumen, Matrii Sulfas Exsiccatus, catechu, Radix Sophorae Flavescentis, Fructus Malvae, Herba Plantaginis, Radix Angelicae Sinensis, Iris speculatrix Hance, Lignum Xanthoceratis, Herba Stachytarphetae Jamaicensis, Herba Andrographis, Fructus Trichosanthis, Spica Prunellae, Folium Artemisiae Argyi, Caulis Sargentodoxae, Rhizoma Acori Graminei, Pseudobulbus Bletillae (Rhizoma Bletillae), Sanguis Draxonis, Dioscorea panthaica Prain et Burkill, Fructus Lycii, Herba Corydalis Bungeanae, Fructus Evodiae, Radix Morinae Bulleyanae are mixed in proportion, adopt in super micron mill and pulverize, medicinal mixture after pulverizing is dissolved in ethanol, heating and refluxing extraction 2 times ~ 5 times, filter, merge all filtrate, vacuum-concentrcted removes ethanol, obtains dry mastic A;
Second step, adopts Radix Glycyrrhizae, Flos Mume the medicine powder component B pulverized in super micron mill;
3rd step, cleans Radix Bupleuri, dries, and is placed in container, mixes thoroughly with vinegar, puts in pot and fries with slow fire, fries and to exhaust and micro-dry to vinegar, take out, dry, be placed in mortar, grind into powder, cross 200 order fine powder C for subsequent use;
4th step, adds capsule adjuvant, sterilizing by the A of above-mentioned acquisition, B, component C, and packaging, gets product.
Present invention also offers the using method of above-mentioned Chinese medicine composition, comprise the following steps: the pharmaceutical composition taking out treatment cervicitis, is dissolved in 100-1000mL warm water, after medicine fully dissolves, rinse affected part, once a day.
Fang Xie:
Olibanum: " Bencao Jingshu " is recorded into lunar, the hands of foot few cloudy, double enter meridian of Foot-JUE YIN; Cure mainly regulating qi and activating blood, analgesic therapy, chase after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Bencao Jingshu ": edema due to wind pathogen poison is swollen, invade in evil dry heart spleen, bad odor, also by two through empty and evilly easily to violate.Urticaria itch poison, always because heart spleen causes it by rheumatism pathogenic heat is dry.Spleen governing muscles and sufferings skin infection all belongs to heart-fire, this medicine is just entering two warps, and Xin Xiangneng falls apart, and all stay knot, then all cards are from recover." solar corona " cloud, soft extracts pain relieving is put on flesh; CHEN Zang-Qi cloud, controls married woman's vim and vigour; Treat all skin ulcers, make internal diabetes.Then moderns are in order to control all pains of internal injury, and the medicine of toxic swelling Orally taken and externally, have from the beginning.
Fructus Schisandrae Chinensis: have and astringe the lung, nourishing kidney, promotes the production of body fluid, and receives antiperspirant, arresting seminal emission.Control the deficiency of the lung to breath with cough, xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery." Bencao Jingshu ": the main QI invigorating person of Fructus Schisandrae Chinensis, all gas of lung master, acid can be received, and just entering lung tonifying the lung, therefore QI invigorating also.Its main cough with dyspnea person, the deficiency of vital energy is then above stopped up and is not returned unit, sour flavor having the property of astringing, takes the photograph gas and returns unit, then cough with dyspnea is from removing.Impairment caused by overstrain weakness and emaciation, tonifying for the deficiency, reinforcing YIN-essence, beneficial man's essence." not Lu " supports the five internal organs, heat extraction, flesh person in raw the moon, the special the kidney invigorating of Fructus Schisandrae Chinensis, tonifying five ZANG-organs of holding concurrently, kidney storing essence, and essence is contained then cloudy strong, and receive and take the photograph, vital qi returns unit, and public region is warmed up, digesting food, steams waste matter and changes precise and tiny, then smart spontaneous, and essence is raw then cloudy long, therefore main as above all diseases also.
Fructus Cnidii; Nature and flavor, warm in nature, bitter.Function cures mainly: warming the kidney to invigorate YANG, and dampness is dispeled the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.
Dried Alumen: sour in the mouth, cold.Function cures mainly: expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, parasite killing.Control epilepsy, sore throat, remorse saliva is stopped up very, hepatitis, jaundice, general edema with yellowish skin, taste-blindness rate, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite." detailed outline ": " tell lower sputum drink phosphorus, dampness is detoxified, and chases after saliva, hemostasis analgesic therapy, and meat is disliked in erosion, and raw good meat is controlled carbuncle furuncle and swollen, malignant boil, epilepsy, subcutaneous ulcer disease, relieving bowels, all diseases of ability to speak eyes, brave dog snakes and scorpions hundred insect bite.″
Matrii Sulfas Exsiccatus: purgatives medicine; Softening the hard mass medicine; Heat and toxic materials clearing away medicine, Xin Xian; Cold; Nontoxic, " detailed outline ": " legendary god of farming's book on Chinese herbal medicine " speech, Mirabilitum refining bait takes it, and make light of one's life by commiting suicide angle.The speech that lid necromancer scurries into.Therefore descendant is made as Matrii Sulfas Exsiccatus.Enure multipass, helps with Radix Glycyrrhizae, removes the poison that it is salty-cold, and meet three burnt the intestines and stomach excess-heat and stagnate, the juvenile gas person of strengthening, measures and take it, also having immediate effect.Air slaking disappear, sweet slow frivolous, therefore control part of the body cavity above the diaphragm housing the heart and lungs cardiopulmonary expectorant heat and do not let out profit.
Catechu: to protect the liver, choleretic effect; Promote the removing of hepatitis B antigen; Resisting pathogenic microbes effect; Suppress intestinal movement and anti-CaM antibody; Hypoglycemic activity; Effect to blood and cardiovascular system: cachou extract has the effects such as significant antiplatelet aggregation, antithrombus formation; Analgesic activity.
Radix Sophorae Flavescentis: function cures mainly heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy.Compendium of Material Medica: the bitter cold of Radix Sophorae Flavescentis, Cortex Phellodendri, all can the kidney invigorating, and lid gets its bitter dampness, and cold heat extraction also.Hot air wind producing, humidogene worm, therefore wind parasite killing can be controlled again.Only kidney water is weak and mutually fiery victor is suitable with it, the cold sperm if fire declines, and true strength is not enough, and year high people is also unavailable.ZHANG Cong-zheng is cloud also, all medicines all poison also, though Radix Glycyrrhizae, Radix Sophorae Flavescentis, can not poison unexpectedly, take for a long time, the five tastes respectively return it dirty, must have the trouble of victory gas increasings partially, and all medicines are all right, scholar's length when tactile class can also, as the same as diet.Again by " Records of the Historian " cloud, the sick dental caries of granary public Chunyu Yi doctor doctor Qi, moxibustion left hand yangming meridian, gargles three liters with kuh-seng soup day, careful wind of coming in and going out, and more this also got the justice that it removes the damp and hot parasite killing of pathogenic wind on five, six.
Fructus Malvae: meridian distribution of property and flavor; Sweet, puckery, cool.Function cures mainly: clearing away heat and promoting diuresis, detumescence.For urine retention, edema, thirsty; Urinary tract infection.
Herba Plantaginis: nature and flavor: sweet, cold.Gui Jing: return liver, kidney, lung, small intestine meridian.Function cures mainly: clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Herba Plantaginis: nature and flavor: sweet, cold.Gui Jing: return liver, kidney, lung, small intestine meridian.Function cures mainly: clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Radix Angelicae Sinensis: having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Availablely control apoplexy syncope, spit out white foams, puerperal paralysis.There is oxygen lack resistant function; Conditioner body immunity function, there is antitumaous effect; Cosmetology effect; To enrich blood the effect of invigorating blood circulation; Antibacterial, arteriosclerosis effect.
Iris speculatrix Hance: nature and flavor: pungent, prevents, slightly poisonous.Function cures mainly: deliver loose wind; With middle removing dampness; Hemostasis.Main anemofrigid cold; Vomiting; Leakage is rushed down; Wind dampness rheumatic anesthesia pain; Eczema pruritus; Beriberi wets rotten; Knife injury is hemorrhage.
Lignum Xanthoceratis: Wen Gan, flat, expelling wind and removing dampness.
Herba Stachytarphetae Jamaicensis: nature and flavor: micro-hardship, cold.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main pyretic stranguria; Stranguria caused by urinary stone; Nebulousurine; Leucorrhea; Rheumatic ostalgia; Acute conjunctivitis; Pharyngolaryngitis; Gingivitis; Cholecystitis; Carbuncle furuncle; Hemorrhoid; Treating swelling and pain by traumatic injury.
Herba Andrographis: nature and flavor: bitter, cold.Gui Jing: GUIXIN, lung, large intestine, urinary bladder channel.Function cures mainly: heat-clearing and toxic substances removing, removing heat from blood, detumescence.For cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, venom.
Fructus Trichosanthis: have antipyreticly to quench the thirst, diuresis, the effect such as relieving cough and expelling phlegm.Seed is containing fat flower fat oil; Fruit is containing triterpene saponin, organic acid, resin, saccharide, color element; Root is containing protein, saponin, acids." detailed outline ": " Fructus Trichosanthis, its root is directly lower raw, Nian Jiuzhe long number chi, and pick person is solid after autumn powder, and Xia Yue pick person has muscle without powder, can't bear to use.Circle is long in fact, and as melon time blue or green, as ripe Fructus Kaki time yellow, mountain man children's also eats it.Inside have flat son, large as Semen Luffae, shell color is brown, and core color is green, greasiness, makes blue or green gas.”
Spica Prunellae: the property of medicine: pungent, bitter, cold.Return liver, gallbladder meridian.Clearing away heat-fire, improving eyesight, mass dissipating and swelling eliminating.For conjunctival congestion and swelling pain, dizzy, order pearl nyctalgia of having a headache; Scrofula, goiter; Acute mastitis swells and ache.
Folium Artemisiae Argyi: Folium Artemisiae Argyi acrid in the mouth, hardship, warm in nature, nontoxic; Return spleen, liver, kidney channel; Fragrance temperature is loose, can rise to fall to have warming the meridian for stopping bleeding, dispersing cold for relieving pain, effect of wet down parasite killing.Cure mainly menoxenia, dysmenorrhea, infertility, frequent fetal movement, trusted subordinate's cold type of pain, spit blood, epistaxis, spitting of blood, has blood in stool, metrorrhagia, gestation hemorrhage, chronic dysentery of having loose bowels, leukorrhagia, eczema, scabies, carbuncle, hemorrhoid, moxibustion treatment all kinds of diseases and ailments.
Caulis Sargentodoxae: nature and flavor are bitter, flat.There is the eliminating carbuncle that relieves internal heat, promoting blood circulation to remove obstruction in the collateral, the effect of wind dispelling insecticide.Control acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, injury from falling down.
Rhizoma Acori Graminei: function cures mainly: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.
Pseudobulbus Bletillae (Rhizoma Bletillae): be mainly used in astringing to arrest bleeding, detumescence and promoting granulation.Meridian distribution of property and flavor: bitter in the mouth, sweet, puckery, cold in nature, returns lung, liver, stomach warp.There is astringing to arrest bleeding, the merit of detumescence and promoting granulation, for all cards of interior external haemorrhage and carbuncle, scald, rhagadia manus et pedis, anal fissure etc.
Sanguis Draxonis: effect: promoting blood circulation to remove blood stasis for oral administration, analgesic therapy, external hemostasia and promoting granulation, sore.There is promoting blood circulation to remove blood stasis, analgesic therapy, effect of hemostasia and promoting granulation.For congestion amenorrhea, dysmenorrhea, postpartum stagnation; Lump in the abdomen mass in the abdomen, breast ventral spine pain; Traumatic injury, congestion swells and ache; Traumatic hemorrhage, ulcer being unable to heal.
Dioscorea panthaica Prain et Burkill: nature and flavor: sweet, micro-pungent, flat.Function cures mainly: removing toxic substances and promoting subsidence of swelling, pain relieving.For stomachache, traumatic injury; Tuberculous lymphadenitis is controlled in external.
Fructus Lycii: nature and flavor: sweet is flat.Gui Jing: return liver, kidney channel.Function cures mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Herba Corydalis Bungeanae: heat-clearing and toxic substances removing, controls the high heat of epidemic febrile disease irritated, influenza, infectious hepatitis, nephritis, scrofula, parotitis, furuncle and other pyogenic infection.Function cures mainly: heat-clearing and toxic substances removing; Subduing inflammation.Main influenza; Upper respiratory tract infection; Tonsillitis; Infectious hepatitis; Intestinal is scorching; Dysentery; Nephritis; Parotitis; Conjunctivitis.
Fructus Evodiae: warming middle-JIAO, pain relieving, regulates the flow of vital energy, dampness, and stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation, Diarrhoea, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.
Radix Morinae Bulleyanae: record in supplementary Amplifications of the Compendium of Materia Medica: Stichopus japonicus, sweet-salty, the kidney invigorating, beneficial marrow, takes the photograph urine, and flaccidity is treated in tonifying YANG, its benefit warm in nature, sufficient enemy's ginseng, therefore named Stichopus japonicus.Modern study shows, Stichopus japonicus has raising memory, delays gonad aging, prevents the effects such as arteriosclerosis, diabetes and antitumor.
Radix Bupleuri: another name ground is smoked, mountain dish, mushroom are careless, faggot.Nature and flavor are bitter, are slightly cold.Return liver, gallbladder meridian.There is reconciling superficies and interior, soothing the liver, effect of yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.Nature and flavor: bitter, cool.Gui Jing: enter liver, gallbladder meridian; " detailed outline ": control yang-energy and sink, suppressing the hyperactive liver, gallbladder, three burnt, envelope is mutually fiery, and headache, dizzy, and blurred vision, swelling pain are hidden from view, deaf ring, all malarias, and lump at the left hypochondrium cold and heat, married woman's invasion of the blood-chamber by heat, irregular menstruation, children's's varioliform exanthema waste heat, the thin heat of five kinds of child malnutrition.
Chinese crude drug is the mature fruit of Meliaceae deciduous tree toosendanin, cold in nature, and bitter in the mouth is the one of qi-activating drug.There are soothing liver-QI promoting the circulation of QI to relieve pain, the drug effect of anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.But also be make efficiently without the important source material of the free of contamination novel plant pesticide of residual hazard.The sedimentation of Fructus Toosendan bitter cold, mainly enters Liver Channel, catharsis liver-heat, and promoting the circulation of QI to relieve pain, control the stagnation of QI and have the card of heat especially suitable.
Radix Glycyrrhizae: there is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.For insufficiency of heart-QI, severe palpitation, irregularly intermittent and regularly intermittent pulse, and deficiency of spleen-QI and stomach-QI, fatigue and weakness etc.; For ulcer sores, laryngopharynx swelling and pain etc.; For asthma and cough; For stomachache, stomachache and the anxious pain of gastrocnemius contraction etc.; Normal with the same use of Radix Paeoniae, significantly can strengthen the curative effect controlling contraction urgency pain, as peony and licorice decoction; For being in harmonious proportion the strong of some drugs.
Flos Mume: dissipating depression of QI and in, expelling summer-heat, promote the production of body fluid, reduce phlegm, detoxify.Cure mainly: the cough of acute and chronic pharyngitis, hoarseness, aphonia, abundant expectoration, pertussis, acute conjunctivitis, inappetence, dizziness, burn due to hot liquid or fire, measles, dysmenorrhea etc.
In sum, the present invention has heat-clearing and toxic substances removing, effect of sterilizing and itch-relieving, has good therapeutic effect to cervicitis.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine composition effective ingredient of the present invention and parts by weight are: Olibanum 30 parts, Fructus Schisandrae Chinensis 25 parts, Fructus Cnidii 15 parts, dried Alumen 15 parts, Matrii Sulfas Exsiccatus 15 parts, 25 parts, catechu, Radix Sophorae Flavescentis 25 parts, Fructus Malvae 30 parts, Herba Plantaginis 25 parts, Radix Angelicae Sinensis 30 parts, 15 parts, Radix Glycyrrhizae, Iris speculatrix Hance 30 parts, Lignum Xanthoceratis 20 parts, 30 parts, Flos Mume, Herba Stachytarphetae Jamaicensis 20 parts, Herba Andrographis 30 parts, Fructus Trichosanthis 30 parts, Spica Prunellae 15 parts, Folium Artemisiae Argyi 20 parts, Caulis Sargentodoxae 25 parts, Rhizoma Acori Graminei 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Sanguis Draxonis 30 parts, Dioscorea panthaica Prain et Burkill 40 parts, Fructus Lycii 25 parts, Herba Corydalis Bungeanae 20 parts, Fructus Evodiae 30 parts, Radix Morinae Bulleyanae 8 parts, Radix Bupleuri 20 parts.
Present invention also offers the preparation method of above-mentioned Chinese medicine composition, comprise the following steps:
The first step, Olibanum, Fructus Schisandrae Chinensis, Fructus Cnidii, dried Alumen, Matrii Sulfas Exsiccatus, catechu, Radix Sophorae Flavescentis, Fructus Malvae, Herba Plantaginis, Radix Angelicae Sinensis, Iris speculatrix Hance, Lignum Xanthoceratis, Herba Stachytarphetae Jamaicensis, Herba Andrographis, Fructus Trichosanthis, Spica Prunellae, Folium Artemisiae Argyi, Caulis Sargentodoxae, Rhizoma Acori Graminei, Pseudobulbus Bletillae (Rhizoma Bletillae), Sanguis Draxonis, Dioscorea panthaica Prain et Burkill, Fructus Lycii, Herba Corydalis Bungeanae, Fructus Evodiae, Radix Morinae Bulleyanae are mixed in proportion, adopt in super micron mill and pulverize, medicinal mixture after pulverizing is dissolved in ethanol, heating and refluxing extraction 2 times, filter, merge all filtrate, vacuum-concentrcted removes ethanol, obtains dry mastic A;
Second step, adopts Radix Glycyrrhizae, Flos Mume the medicine powder component B pulverized in super micron mill;
3rd step, cleans Radix Bupleuri, dries, and is placed in container, mixes thoroughly with vinegar, puts in pot and fries with slow fire, fries and to exhaust and micro-dry to vinegar, take out, dry, be placed in mortar, grind into powder, cross 200 order fine powder C for subsequent use;
4th step, adds capsule adjuvant, sterilizing by the A of above-mentioned acquisition, B, component C, and packaging, gets product.
Embodiment 2
The raw material composition of Chinese medicine composition effective ingredient of the present invention and parts by weight are: Olibanum 20 parts, Fructus Schisandrae Chinensis 15 parts, Fructus Cnidii 10 parts, dried Alumen 10 parts, Matrii Sulfas Exsiccatus 15 parts, 15 parts, catechu, Radix Sophorae Flavescentis 20 parts, Fructus Malvae 20 parts, Herba Plantaginis 25 parts, Radix Angelicae Sinensis 30 parts, 15 parts, Radix Glycyrrhizae, Iris speculatrix Hance 20 parts, Lignum Xanthoceratis 15 parts, 20 parts, Flos Mume, Herba Stachytarphetae Jamaicensis 15 parts, Herba Andrographis 15 parts, Fructus Trichosanthis 15 parts, Spica Prunellae 15 parts, Folium Artemisiae Argyi 20 parts, Caulis Sargentodoxae 15 parts, Rhizoma Acori Graminei 25 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Sanguis Draxonis 15 parts, Dioscorea panthaica Prain et Burkill 20 parts, Fructus Lycii 20 parts, Herba Corydalis Bungeanae 15 parts, Fructus Evodiae 16 parts, Radix Morinae Bulleyanae 8 parts, Radix Bupleuri 10 parts.
Preparation method is as embodiment 1
Embodiment 3
The raw material composition of Chinese medicine composition effective ingredient of the present invention and parts by weight are: Olibanum 50 parts, Fructus Schisandrae Chinensis 50 parts, Fructus Cnidii 40 parts, dried Alumen 40 parts, Matrii Sulfas Exsiccatus 60 parts, 30 parts, catechu, Radix Sophorae Flavescentis 50 parts, Fructus Malvae 50 parts, Herba Plantaginis 60 parts, Radix Angelicae Sinensis 45 parts, 30 parts, Radix Glycyrrhizae, Iris speculatrix Hance 60 parts, Lignum Xanthoceratis 30 parts, 45 parts, Flos Mume, Herba Stachytarphetae Jamaicensis 50 parts, Herba Andrographis 40 parts, Fructus Trichosanthis 30 parts, Spica Prunellae 40 parts, Folium Artemisiae Argyi 60 parts, Caulis Sargentodoxae 25 parts, Rhizoma Acori Graminei 45 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 50 parts, Sanguis Draxonis 30 parts, Dioscorea panthaica Prain et Burkill 60 parts, Fructus Lycii 45 parts, Herba Corydalis Bungeanae 35 parts, Fructus Evodiae 60 parts, Radix Morinae Bulleyanae 10 parts, Radix Bupleuri 60 parts.
Preparation method is as embodiment 1
Using method of the present invention takes out the pharmaceutical composition for the treatment of cervicitis, is dissolved in 800mL warm water, after medicine fully dissolves, rinses affected part, once a day.
Toxicity test:
Laboratory animal
SD rat is provided by Qingdao City's Experimental Animal Center.
Toxicity test:
Choose SD rat 80, be divided into matched group, experimental group often to organize 30, male and female half and half.Matched group adopts normal saline gavage, and experimental group adopts the present embodiment 1 gavage, three times on the one gavages, successive administration 30 weeks, observes the index such as animal ordinary circumstance and body weight.Drug withdrawal is after three days, and observe the index such as hair, behavior, defecation, body weight of SD rat, result shows all to have no significant effect, and internal organs naked eyes do not find difference change.Put to death rat, tissue slice is carried out to its internal organs, shows without any pathological changes and exception under Electronic Speculum.
Illustrate that medicine of the present invention is little to toxicity after SD rat long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Clinical trial:
Therapeutic scheme: take the circumstances into consideration administration according to the state of an illness.
The standard of curative effect evaluation: determine curative effect with reference to " new Chinese medicine guideline of clinical investigations ".
Clinical recovery: vaginal secretions increases, in mucus purulence, guides secretions to stimulate and can cause the transference cure such as pruritus vulvae and burning sensation.In addition, the transference cure such as intermenstrual bleeding, postcoital bleeding.Merge urinary tract infection, the hyperemia of urethral orifice, vaginal orifice mucosa, edema and volume purulent secretion transference cure.
Effective: vaginal secretions increases, in mucus purulence, guide secretions to stimulate and the symptom such as pruritus vulvae and burning sensation can be caused to improve.In addition, the symptom such as intermenstrual bleeding, postcoital bleeding is alleviated to some extent.Merge urinary tract infection, the hyperemia of urethral orifice, vaginal orifice mucosa, edema and volume purulent secretion symptom make moderate progress.
Invalid: vaginal secretions increases, in mucus purulence, guide secretions to stimulate and can cause the exacerbation of symptoms such as pruritus vulvae and burning sensation.In addition, the exacerbation of symptoms such as intermenstrual bleeding, postcoital bleeding.Merge urinary tract infection, the hyperemia of urethral orifice, vaginal orifice mucosa, edema and volume purulent secretion exacerbation of symptoms trend.
Therapeutic outcome: the present invention treats the cervicitis Chinese medicine composition clinical practice several years, totally 268 people take, and wherein women accounts for 54%, and male accounts for 46%, take medicine after a course for the treatment of, symptom takes a turn for the better all to some extent, after three courses for the treatment of of taking medicine, and 125 people's recoveries from illness, 100 people are effective, 43 people are invalid, effective percentage 84%, and curative effect of medication of the present invention is remarkable.
Case 1 female Liu
Symptom: post-abortion leucorrhoea grow in quantity, yellow skin abnormal flavour, lower abdomen pain half a year, lumbosacral region falling inflation.Vagina moderate pus tears sample secretions, have abnormal flavour, cervical erosion concomitant fertilizer is large; Leucorrhea and antibacterial culturing have all confirmed infection; Colposcopy: severe cervical erosion concomitant fertilizer is large, cervical biopsy gets rid of pernicious possibility.
Diagnosis: cervical hypertrophy chronic cervicitis moderate cervical erosion.
Therapeutic process: take capsule of the present invention every day, each two, once a day.Rinse after 3 days, symptom is alleviated, and rinse after 5 days, symptom is obviously improved, and after taking 8 days, patient returns to one's perfect health.
Case 2 Zhang 32
Symptom: because " vagina is smooth, inside sees a little blood; cervical hypertrophy, sees nano-capsule for unregular vaginal bleeding 20 days, abdominal part falling inflation 1 day, and uterus and double accessory district do not lay one's hand on and definitely extremely, B ultrasonic is pointed out: left renal calculus; right adnexal cyst, a little hydrops in rear, uterus, intrauterine contraceptive device in utero.
Diagnosis: menoxenia; Cervicitis.
Therapeutic process: take capsule of the present invention every day, each two, once a day.Rinse after 3 days, symptom is alleviated, and rinse after 3 days, patient returns to one's perfect health.
Case 3 Zheng 48
Symptom: vagina moderate pus tears sample secretions, have abnormal flavour, cervical erosion concomitant fertilizer is large; Leucorrhea and antibacterial culturing have all confirmed infection; Colposcopy: severe cervical erosion concomitant fertilizer is large, cervical biopsy gets rid of pernicious possibility.The conventional hematuria of gynecological routine examination leucorrhea conventional cervical cytological examination colposcopy HPV antibacterial culturing drug sensitive test mycoplasma chlamydia checks.
Diagnosis: cervical hypertrophy chronic cervicitis moderate cervical erosion.
Therapeutic process: take capsule of the present invention every day, each two, once a day.Rinse after 3 days, symptom is alleviated, and rinse after 4 days, patient returns to one's perfect health.
Case 4 Qin so-and-so 46
Symptom: post-abortion leucorrhoea grow in quantity, yellow skin abnormal flavour, lower abdomen pain half a year, lumbosacral region falling inflation, vagina moderate pus tears sample secretions, have abnormal flavour, cervical erosion concomitant fertilizer is large; Leucorrhea and antibacterial culturing have all confirmed infection; Colposcopy: severe cervical erosion concomitant fertilizer is large, cervical biopsy gets rid of pernicious possibility.
Diagnosis: cervical hypertrophy; Chronic cervicitis; Moderate cervical erosion.
Therapeutic process: take capsule of the present invention every day, each two, once a day.Rinse after 2 days, symptom is alleviated, and rinse after 2 days, patient returns to one's perfect health.
Case 5 king so-and-so 30
Symptom: patient's readme occurred waist sacrum and lower abdominal pain before half a year, through time pain increase the weight of, especially based on falling pain, companion leucorrhea amount is many, yellow skin, matter is thick, and taste is smelly, leucorrhea band blood once in a while, within 1 week, cause participates in heavy physical labour aggravation, and the capable colposcopy of provincial hospital of dieing is diagnosed as chronic cervicitis, capable any treatment, today is anxious to our hospital, and outpatient service admits to hospital with " chronic cervicitis ".
Diagnosis: chronic cervicitis
Therapeutic process: take capsule of the present invention every day, each two, once a day.Rinse after 3 days, symptom is alleviated, and rinse after 4 days, patient returns to one's perfect health.
The above; it is only most preferred embodiment of the present invention; not any pro forma restriction is done to the present invention; any those of ordinary skill in the art; do not departing under technical solution of the present invention ambit; utilize the method content of above-mentioned announcement to make many possible variations and modification to technical solution of the present invention, all belong to the scope of claims protection.

Claims (5)

1. treat the Chinese medicine composition of cervicitis for one kind, it is characterized in that: be made up of each component of following parts by weight: Olibanum 10-50 part, Fructus Schisandrae Chinensis 10-50 part, Fructus Cnidii 5-40 part, dried Alumen 5-40 part, Matrii Sulfas Exsiccatus 10-60 part, catechu 10-30 part, Radix Sophorae Flavescentis 10-50 part, Fructus Malvae 10-50 part, Herba Plantaginis 20-60 part, Radix Angelicae Sinensis 20-45 part, Radix Glycyrrhizae 10-30 part, Iris speculatrix Hance 10-60 part, Lignum Xanthoceratis 10-30 part, Flos Mume 15-45 part, Herba Stachytarphetae Jamaicensis 10-50 part, Herba Andrographis 10-40 part, Fructus Trichosanthis 10-30 part, Spica Prunellae 10-40 part, Folium Artemisiae Argyi 10-60 part, Caulis Sargentodoxae 10-25 part, Rhizoma Acori Graminei 10-45 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-50 part, Sanguis Draxonis 10-30 part, Dioscorea panthaica Prain et Burkill 10-60 part, Fructus Lycii 10-45 part, Herba Corydalis Bungeanae 10-35 part, Fructus Evodiae 10-60 part, Radix Morinae Bulleyanae 5-10 part, Radix Bupleuri 5-60 part.
2. a kind of Chinese medicine composition for the treatment of cervicitis according to claim 1, it is characterized in that: be made up of each component of following parts by weight: Olibanum 20-50 part, Fructus Schisandrae Chinensis 15-50 part, Fructus Cnidii 10-40 part, dried Alumen 10-40 part, Matrii Sulfas Exsiccatus 15-60 part, catechu 15-30 part, Radix Sophorae Flavescentis 20-50 part, Fructus Malvae 20-50 part, Herba Plantaginis 25-60 part, Radix Angelicae Sinensis 30-45 part, Radix Glycyrrhizae 15-30 part, Iris speculatrix Hance 20-60 part, Lignum Xanthoceratis 15-30 part, Flos Mume 20-45 part, Herba Stachytarphetae Jamaicensis 15-50 part, Herba Andrographis 15-40 part, Fructus Trichosanthis 15-30 part, Spica Prunellae 15-40 part, Folium Artemisiae Argyi 20-60 part, Caulis Sargentodoxae 15-25 part, Rhizoma Acori Graminei 20-45 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-50 part, Sanguis Draxonis 15-30 part, Dioscorea panthaica Prain et Burkill 20-60 part, Fructus Lycii 20-45 part, Herba Corydalis Bungeanae 15-35 part, Fructus Evodiae 16-60 part, Radix Morinae Bulleyanae 8-10 part, Radix Bupleuri 10-60 part.
3. a kind of Chinese medicine composition for the treatment of cervicitis according to claim 1, it is characterized in that: be made up of each component of following parts by weight: Olibanum 30 parts, Fructus Schisandrae Chinensis 25 parts, Fructus Cnidii 15 parts, dried Alumen 15 parts, Matrii Sulfas Exsiccatus 15 parts, 25 parts, catechu, Radix Sophorae Flavescentis 25 parts, Fructus Malvae 30 parts, Herba Plantaginis 25 parts, Radix Angelicae Sinensis 30 parts, 15 parts, Radix Glycyrrhizae, Iris speculatrix Hance 30 parts, Lignum Xanthoceratis 20 parts, 30 parts, Flos Mume, Herba Stachytarphetae Jamaicensis 20 parts, Herba Andrographis 30 parts, Fructus Trichosanthis 30 parts, Spica Prunellae 15 parts, Folium Artemisiae Argyi 20 parts, Caulis Sargentodoxae 25 parts, Rhizoma Acori Graminei 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Sanguis Draxonis 30 parts, Dioscorea panthaica Prain et Burkill 40 parts, Fructus Lycii 25 parts, Herba Corydalis Bungeanae 20 parts, Fructus Evodiae 30 parts, Radix Morinae Bulleyanae 8 parts, Radix Bupleuri 20 parts.
4. a kind of preparation method for the treatment of the Chinese medicine composition of cervicitis according to claim 1, is characterized in that: comprise the following steps:
The first step, Olibanum, Fructus Schisandrae Chinensis, Fructus Cnidii, dried Alumen, Matrii Sulfas Exsiccatus, catechu, Radix Sophorae Flavescentis, Fructus Malvae, Herba Plantaginis, Radix Angelicae Sinensis, Iris speculatrix Hance, Lignum Xanthoceratis, Herba Stachytarphetae Jamaicensis, Herba Andrographis, Fructus Trichosanthis, Spica Prunellae, Folium Artemisiae Argyi, Caulis Sargentodoxae, Rhizoma Acori Graminei, Pseudobulbus Bletillae (Rhizoma Bletillae), Sanguis Draxonis, Dioscorea panthaica Prain et Burkill, Fructus Lycii, Herba Corydalis Bungeanae, Fructus Evodiae, Radix Morinae Bulleyanae are mixed in proportion, adopt in super micron mill and pulverize, medicinal mixture after pulverizing is dissolved in ethanol, heating and refluxing extraction 2 times-5 times, filter, merge all filtrate, vacuum-concentrcted removes ethanol, obtains dry mastic A;
Second step, adopts Radix Glycyrrhizae, Flos Mume the medicine powder component B pulverized in super micron mill;
3rd step, cleans Radix Bupleuri, dries, and is placed in container, mixes thoroughly with vinegar, puts in pot and fries with slow fire, fries and to exhaust and micro-dry to vinegar, take out, dry, be placed in mortar, grind into powder, cross 200 order fine powder C for subsequent use;
3rd step, adds capsule adjuvant, sterilizing by the A of above-mentioned acquisition, B, component C, and packaging, gets product.
5. a kind of using method for the treatment of the Chinese medicine composition of cervicitis according to claim 1 or 4, is characterized in that: the pharmaceutical composition taking out treatment cervicitis, is dissolved in 100-1000mL warm water, after medicine fully dissolves, rinses affected part, once a day.
CN201410582115.6A 2014-10-17 2014-10-17 Traditional Chinese medicine composition for treating cervicitis Pending CN104288518A (en)

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CN111700968A (en) * 2020-07-11 2020-09-25 杭州承影生物科技有限公司 Compact, antibacterial and anti-inflammation medicine-containing capsule formula for female private care

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CN111700968A (en) * 2020-07-11 2020-09-25 杭州承影生物科技有限公司 Compact, antibacterial and anti-inflammation medicine-containing capsule formula for female private care

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Application publication date: 20150121