CN105687938A - Traditional Chinese medicine preparation for anal fissure and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for anal fissure and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for anal fissure. The raw materials include sanguisorba officinalis, fructus sophorae, herba agrimoniae, herba cirsii, circium japonicum, pseudo-ginseng, radix salviae miltiorrhizae, herba cistanche, fructus cannabis, rheum officinale, radix aucklandiae, radix astragali, chinese angelica, rhizoma cimicifugae, cortex moutan, radix paeoniae rubra, fructus forsythiae, lonicera japonica, folium isatidis, herba violae, flos chrysanthemi indici, rhizoma smilacis glabrae, stem of sargentg loryvine, herba portulacae, Chinese pulsatilla root and lithospermum purpurocaeruleum; and the traditional Chinese medicine preparation belongs to the invention field of traditional Chinese medicines. According to different characteristics of the traditional Chinese medicines, the traditional Chinese medicines are pretreated by cleaning and chopping and then mixed proportionally; the traditional Chinese medicine preparation is prepared by a special method and has the functions of cooling blood and stopping bleeding, clearing heat and relieving pain, moistening intestines to relieve constipation and diminishing swelling and dissipating mass; the combination and preparation methods of the product are unique; and according to clinical verification, the traditional Chinese medicine preparation has the advantages of remarkable treatment effect, short treatment cycle, low price and no adverse reaction or toxic or side effect and has a broad market application prospect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for anal fissure, the preparation method that the invention still further relates to this Chinese medicine preparation。
Background technology
Anus is anal canal, and splitting is split, and anal fissure is that digestive tract outlet is split from tooth trace to the anal canal tissue surface that anus this section of edge is the narrowest, a kind of disease repeatedly not healed。The modal position of anal fissure is the center, front and back of anus, and center was for many in the past。Burning property pain when anal fissure cardinal symptom is defecation and after defecation, and have spastic increasing the weight of, begin to alleviate after continuing half an hour or longer time。Then feel anus mouth discomfort or pruritus at ordinary times。During defecation, anal fissure often has hemorrhage on a small quantity。The feature of symptom is: constipation, pain, hemorrhage reciprocal causation。
Chinese medicine is thought, the people of the pungent savoury of this cause of disease addiction, causes accumulation of heat dryness of the intestine or damp invasion of lower energizer or YIN fluid being insufficient, and feces is hard dry, it is difficult to discharge, and exerts by force then damage anus and causes hemorrhage pain symptom。
At present, anal fissure there is no specific short。Put on the skin outside MAYINGLONGZHICHUANGGAO, erythromycin ointment, indomethacin suppository, hibitane hemorrhoid suppository receive anus etc. anti-inflammatory analgetic effect, and treatment disease is played certain curative effect, and severe patient takes surgical cut to treat。But the long-term or short time uses these medicines to treat, after drug withdrawal, primary affection knock-on increases the weight of the side effect with secondary, and patient can be made to produce very big misery, therapeutic process is again and again, DeGrain, expense is high, causes bigger pressure at heart and ailing pressure to patient。
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation for anal fissure, it is notable that this Chinese medicine preparation has therapeutic effect for treatment anal fissure, and healing time is short, cheap, and have no adverse reaction the feature with secondary toxic action。
Inventor in clinical treatment for many years is put into practice, the law of development according to this disease, and the combination principle of Chinese medicine, and by substantial amounts of clinical verification, Exploration and conclusion goes out the new formula of the Chinese medicine preparation for treating anal fissure repeatedly。It is notable that the present invention has therapeutic effect, and healing time is short, cheap, and have no adverse reaction the feature with secondary toxic action。
The effect of Chinese medicine of the present invention:
Wherein:
Radix Sanguisorbae: for rosaceous plant Radix Sanguisorbae SanguisorbaofficinalisL. or the Radix Sanguisorbae SanguisorbaofficinalisL.var.longifolia(Bert. that comes into leaves) dry root of YuetLi。Nature and flavor: bitter, sour, puckery, are slightly cold。Effect: cooling blood for hemostasis, sore of detoxifying。For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus。Recording in " not Lu ": only pus and blood, all fistulas, malignant boil, disappear wine, except quenching one's thirst, mends wound absolutely, and in puerperal, plug, can make incised wound cream。
The Fructus Sophorae: for the fruit of leguminous plant Chinese scholartree。The honey Fructus Sophorae: first take the Fructus Sophorae and put the interior slow fire stir-fry of pot to heaving, spray into mulse, then fry to crust bright, tack-free for spending, take out and cool (every Fructus Sophorae 100 jin, with refining hot Mel 5 jin)。Nature and flavor: bitter, cold。Return liver, large intestine channel。Effect: heat clearing away, moistens liver, removing heat from blood, hemostasis。Controlling hemorrhoidal hamorrhage and rush down blood, hemorrhoidal bleeding, metrorrhagia, stranguria with blood, dysentery, ambition is unhappy, and dizziness due to wind pathogen is intended to down, erosion of vulva pruritus due to damp pathogen。" herbal classic " is recorded: pathogen heat in main five, only saliva and spittle, mend wound, five hemorrhoid, burn, married woman's breast abdominal mass, sub-Tibetan shoot absolutely。
Herba Agrimoniae: for the dry aerial parts of rosaceous plant Radix Agrimoniae AgrimoniapilosaLedeb.。Nature and flavor: bitter, puckery are flat。GUIXIN, Liver Channel。Effect: astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances。For hemoptysis, spit blood, metrostaxis, malaria, dysentery, de-power impairment caused by overstrain, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia。" BAICAO mirror ": the therapeutic method to keep the adverse QI flowing downwards is invigorated blood circulation, manages all kinds of diseases and ailments, dissipates feeling of fullness；Fall and flutter haematemesis, metrorrhagia, dysentery, discharging fresh blood stool。
Herba Cirsii: for Compositae field thistle platymiscium field thistle Cephalanoplossegetum(Bunge) dry aerial parts (wounded in the battle herb) of Kitam. [CirsiumsegetumBunge], root stock also can be used as medicine。Nature and flavor: sweet, bitter, cold。GUIXIN, Liver Channel。Effect: cooling blood for hemostasis, removing blood stasis to reduce swelling。For epistaxis, spit blood, hematuria, have blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus。Root stock: hepatitis。
Radix Cirsii Japonici: for the aerial parts of feverfew Ji CirsiumjapokicumDC.。Nature and flavor: cool in nature, sweet in the mouth, hardship。Effect: cooling blood for hemostasis, removing blood stasis to reduce swelling。For epistaxis, haematemesis, hematuria, have blood in stool, metrostaxis, traumatic hemorrhage, carbuncle sore tumefacting virus。" Fujian traditional herbal medicine " is recorded: cooling blood for hemostasis, antiinflammatory detumescent。Control lung-heat hemoptysis, accumulation of heat stranguria with blood, furuncle furuncle cancer, dermatitis rhus, the burning hot wound of soup。
Radix Notoginseng: for panax araliaceae plant Panaxnotoginseng(Burk.) dry root of F.H.Chen。Nature and flavor: hardship sweet, micro-, temperature。Return liver, stomach warp。Effect: dissipating blood stasis stops blooding, subduing swelling and relieving pain。For spitting blood, spit blood, epistaxis, to have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling。" jade seizes medicine solution " is recorded: " and battalion's hemostasis, clots absorbing of promoting blood circulation, clots absorbing blood and hold back fresh blood。
Radix Salviae Miltiorrhizae: for the dry root and rhizome of labiate Radix Salviae Miltiorrhizae SalviamiltiorrhizaBunge.。Nature and flavor: bitter, are slightly cold。GUIXIN, Liver Channel。Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness。For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia；Hepatosplenomegaly, angina pectoris。" the southern regions of the Yunnan Province book on Chinese herbal medicine " is recorded: reinforcing the heart sedate, calming heart and tranquilizing mind。Controlling forgetful punching seized with terror, palpitation with fear is insomnia。
Herba Cistanches: for the fleshy stem of the dry zone scale leaf of orobanchaceae plant cistanche CistanchedeserticolaY.C.Ma。Nature and flavor: sweet, salty, temperature。Return kidney, large intestine channel。Effect: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation。For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation。" herbal classic " is recorded: main five kinds of strain and seven kinds of impairment, invigorating middle warmer, except stem invasion by pathogenic cold burning pain, support the five internal organs, reinforcing YIN-essence, benefit vital essence, gynecological mass in abdomen。
Fructus Cannabis: for the dry mature fruit of moraceae plants Fructus Cannabis CannabissativaL.。Nature and flavor: sweet are flat。Return spleen, stomach, large intestine channel。Effect: loosening bowel to relieve constipation。For blood deficiency and depleted fluid, dryness of the intestine constipation。" not Lu " be recorded: main sweating caused by wind pathogen, relieve oedema or abdominal distension through diuresis or purgation, diuresis, removing mass blood, multiple blood vessels, disease more than breast woman puerperal。
Radix Et Rhizoma Rhei: for polygonum rheum palmatum RheumpalmatumL。, Rheum tanguticum RheumtanguticumMaxim。ExBalf。Or Rheum officinale RheumofficinaleBaill。Dry root and rhizome。Nature and flavor: bitter, cold。Return spleen, stomach, large intestine, liver, pericardium channel。Effect: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation。Recording in " not Lu ": flat stomach, the therapeutic method to keep the adverse QI flowing downwards, expectorant is real, stagnation of pathogenic heat between intestinal, trusted subordinate's distension, and the cold blood of woman closes swollen, and lower abdominal pain, all old blood stays knot。
The Radix Aucklandiae: for the dry root of feverfew Radix Aucklandiae AucklandialappaDecne.。Nature and flavor: pungent, bitter, temperature。Return spleen, stomach, large intestine, three burnt, gallbladder meridians。Effect: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion。For breast gastral cavity distending pain, weight after dysentery, food stagnation does not disappear, anorexia。Radix Aucklandiae (roasted) reality intestinal antidiarrheal。For stomachache of having loose bowels。" not Lu " be recorded: treat that gas is bad, partially cold in flesh；Main QI-insufficiency, sterilization, (controlling) pyrexial malaria, the essence of row medicine。
The Radix Astragali: for leguminous plant Radix Astagali Astragalusmembranaceus(Fisch.) Bge.var.mongholicus(Bge.) Hsiao or Radix Astragali Astragalusmembranaceus(Fisch.) dry root of Bge.。Nature and flavor: sweet, temperature。Return lung, spleen channel。Effect: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation。Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and bursts for a long time and does not hold back, and blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst；Chronic nephritis proteinuria, diabetes。
Radix Angelicae Sinensis: for umbelliferae angelica Angelicasinensis(Oliv.) dry root of Diels。Nature and flavor: sweet, acrid, warm。Return liver, the heart, spleen channel。Effect: replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation。For blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores。Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow。For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down。Recording in " not Lu ": warming middle-JIAO to relieve pain, except plug, middle puerperal tetanus, no sweating, arthralgia chiefly caused by damp pathogen in visitor's blood, attacked by pestiferous factors is courteous, cold caused by deficiency, mends five Tibetan, granulation promoting meat。
Rhizoma Cimicifugae: for ranunculaceae plant C.heracleifolia CimicifugaheracleifoliaKom., Cimicifuga Dahurica Cimicifugadahurica(Turcz.) dry rhizome of Maxim. or Rhizoma Cimicifugae CimicifugafoetidaL.。Nature and flavor: pungent, micro-sweet, are slightly cold。Return lung, spleen, stomach, large intestine channel。Effect: deliver rash, heat-clearing and toxic substances removing, rise and lift yang-energy。For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome sends out speckle；Proctoptosis, uterine prolapse。" not Lu " be recorded: main attacked by pestiferous factors is suffered from abdominal pain, seasonal epidemic pathogens poison pestilence, cold and heat of having a headache, all poison of swelling due to wind, laryngalgia, aphtha。
Cortex Moutan: for the dry root bark of ranunculaceae peony PaeoniasuffruticosaAndr.。Nature and flavor: bitter, pungent, are slightly cold。GUIXIN, liver, kidney channel。Effect: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling。For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, fall and flutter the pain of injury。" herbal classic " is recorded: main cold and heat, apoplexy, convulsion, infantile convulsion pathogen, except disease heavily fortified point blood stasis stays house the intestines and stomach, settling five organs, treat ulcerative carbuncle。
Radix Paeoniae Rubra: for the dry root of ranunculaceae plant Radix Paeoniae PaeonialactifloraPall. or river Radix Paeoniae Rubra PaeoniaveitchiiLynch。Nature and flavor: bitter, are slightly cold。Return Liver Channel。Effect: clearing away heat and cooling blood, eliminating stasis to stop pain。For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection。TAO Hong-Jing is said: " the red person's minor benefit of Radix Paeoniae, custom side, with pain relieving, is do not subtract Radix Angelicae Sinensis。
Fructus Forsythiae: for Oleaceae plants Fructus Forsythiae Forsythiasuspensa(Thunb.) dry fruit of Vahl。Nature and flavor: bitter, are slightly cold。Return lung, the heart, small intestine meridian。Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds。For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warm is joined the army, high hot excessive thirst, and coma sends out speckle, pyretic stranguria urine retention。" herbal classic " is recorded: main cold and heat, Mus flaccidity, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat。
Flos Lonicerae: the flower just opened for caprifoliaceae plant Radix Ophiopogonis LonicerajaponicaThunb., Flos Lonicerae LonicerahypoglaucaMiq., the dry flower of Flos Lonicerae (hair calyx Radix Ophiopogonis) LoniceraconfusaDC. or hair style Radix Ophiopogonis LoniceradasystylaRehd. or band。Nature and flavor: sweet, cold。Return lung, the heart, stomach warp。Effect: heat-clearing and toxic substances removing, wind-heat dissipating。For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat。" the SHENGCAO property of medicine is standby to be wanted " is recorded: energy eliminating carbuncle cellulitis furunculosis, dysentery relieving disease, wash chancre, remove the peel skin heat in blood。
Folium Isatidis: for the dried leaves of cruciferae isatis IsatisindigoticaFort.。Nature and flavor: bitter, cold。GUIXIN, stomach warp。Effect: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing。Join the army for pathogenic warmth, unconsciousness due to high fever, send out speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle。Recording in " book on Chinese herbal medicine is just ": control pestilence pyretic toxicity and go mad, wind heat macule, carbuncle and ulcer swells and ache, relieving thirst and restlessness, only epistaxis, haematemesis, kills infantile malnutrition erosion, incised wound curare。All hold concurrently poison person with heat, all LANYE should smash juice and use it。
Herba Violae: for the dry herb of Violaceae Chinese violet ViolayedoensisMakino。Nature and flavor: bitter, acrid, cold。GUIXIN, Liver Channel。Effect: heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling。For furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom。
Flos Chrysanthemi Indici: for the dry capitulum of feverfew chrysanthemum ChrysanthemummorifoliumRamat.。Nature and flavor: sweet, bitter, are slightly cold。Return lung, Liver Channel。Function cures mainly: dissipate wind heat clearing away, suppressing the hyperactive liver improving eyesight。For anemopyretic cold, dizziness of having a headache, conjunctival congestion and swelling pain, eyes is dim-sighted。Recording in " herbal classic ": main all dizziness due to wind, swell and ache, order is intended to de-, lacrimation, the dead flesh of skin, aversion to wind arthralgia chiefly caused by damp pathogen, profit vim and vigour。
Rhizoma Smilacis Glabrae: for the dry rhizome of liliaceous plant smilacis glabra SmilaxglabraRoxb.。Nature and flavor: sweet, light are flat。Return liver, stomach warp。Effect: dehumidifying, removing toxic substances, easing joint movement。For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain。" book on Chinese herbal medicine is just " is recorded: treat carbuncle, sore throat, except the whole body cold-damp, malignant boil。
Caulis Sargentodoxae: for plants of Lardizabalaceae Caulis Sargentodoxae Sargentodoxacuneata(Oliv.) the dry rattan of Rehd.etWils.。Nature and flavor: bitter are flat。Return large intestine, Liver Channel。Effect: heat-clearing and toxic substances removing, invigorates blood circulation, and dispels the wind。For abdominalgia with intestinal abscess, amenorrhea dysmenorrhea, rheumatic arthralgia, tumbling and swelling。" simple and easy medical herbs " is recorded: control bones and muscles pain, chase after wind, strong waist knee joint, tonifying YANG thing。
Herba Portulacae: for portulacaceous plant Herba Portulacae PortulacaoleraceaL., with all herbal medicine。Nature and flavor: acid, cold。Effect: clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body。For bacillary dysentery, acute gastroenteritis, acute appendicitis, mastitis, bleeding hemorrhoids, leucorrhea；Furuncle swelling toxin, eczema, herpes zoster are controlled in external。
The Radix Pulsatillae: for ranunculaceae plant Radix Pulsatillae Pulsatillachinensis(Bge.) dry root of Regel。Nature and flavor: bitter, cold。Return stomach, large intestine channel。Effect: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery。For toxic-heat and blood stasis, pudendal pruritus leukorrhagia, amebic dysentery。" herbal classic " is recorded: the mad easy cold and heat of main pyrexial malaria, lump in the abdomen, goiter, by blood and relieving pain, incised wound。
Radix Arnebiae (Radix Lithospermi): for comfrey lithospermum euchromum Royle Arnebiaeuchroma(Royle) dry root of Johnst., Radix Arnebiae (Radix Lithospermi) LithospermumerythrorhizonSieb.etZucc. or arnebia guttata Bunge ArnebiaguttataBunge。Nature and flavor: sweet, salty, cold。GUIXIN, Liver Channel。Effect: removing heat from blood, invigorates blood circulation, rash of detoxifying。Containing for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire。" detailed outline " is recorded: control macule, pox poison, promoting blood circulation and cooling blood, profit large intestine。
The square solution of the present invention is: Radix Sanguisorbae cooling blood for hemostasis, removing toxic substances sore, the Fructus Sophorae heat clearing away profit liver, cooling blood for hemostasis, Herba Cirsii cooling blood for hemostasis, removing blood stasis to reduce swelling, Radix Cirsii Japonici cooling blood for hemostasis, removing blood stasis to reduce swelling, Cortex Moutan clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, Radix Paeoniae Rubra clearing away heat and cooling blood, eliminating stasis to stop pain, Folium Isatidis heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, Herba Violae heat-clearing and toxic substances removing, removing heat from blood are subsided a swelling, Herba Portulacae clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, Radix Pulsatillae heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, Radix Arnebiae (Radix Lithospermi) removing heat from blood and promoting blood circulation, removing toxic substances rash, above ten Herba indigoferae Pseudotinctoriae, as monarch drug in side, have the effect of cooling blood for hemostasis, clearing away heat to alleviate pain。Chinese medicine is thought, the people of the pungent savoury of this cause of disease addiction, causes accumulation of heat dryness of the intestine or damp invasion of lower energizer or YIN fluid being insufficient, and feces is hard dry, it is difficult to discharges, exerts by force, damages anus and causes hemorrhage due to anal fissure pain symptom。So cooling blood for hemostasis, clearing away heat to alleviate pain are the bases for the treatment of anal fissure, above ten Herba indigoferae Pseudotinctoriae are monarch drug, first fundamentally cooling blood for hemostasis, clearing away heat to alleviate pain, make disease obtain basic control。Herba Cistanches YANG invigorating benefit essence, loosening bowel to relieve constipation, Fructus Cannabis loosening bowel to relieve constipation, Radix Et Rhizoma Rhei purging heat and dredging bowels, eliminating blood stasis and inducing menstruation, Radix Aucklandiae promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, Radix Angelicae Sinensis menstruction regulating and pain relieving, loosening bowel to relieve constipation, Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, Flos Lonicerae heat-clearing and toxic substances removing, wind-heat dissipating, ministerial drug in the above seven flavor medicine side of being, assists effect of monarch drug cooling blood for hemostasis, clearing away heat to alleviate pain on the one hand；There is effect of loosening bowel to relieve constipation, dispersing swelling and dissipating binds on the other hand as ministerial drug。Herba Agrimoniae astringing to arrest bleeding, dysentery relieving detoxify, the hemostasis of Radix Notoginseng dissipating blood stasis, subduing swelling and relieving pain, Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, Rhizoma Cimicifugae heat-clearing and toxic substances removing, liter lift yang-energy, Flos Chrysanthemi Indici dissipates wind heat clearing away, suppressing the hyperactive liver improving eyesight, Rhizoma Smilacis Glabrae removing dampness and detoxicating, easing joint movement, Caulis Sargentodoxae heat-clearing and toxic substances removing, promoting blood circulation by removing wind, above eight taste medicines are as adjuvant drug, from pathology, treatment causes the inducement of anal fissure, can promote effect of the cooling blood for hemostasis of the monarch and his subjects two medicine, clearing away heat to alleviate pain as adjuvant drug, can promote the effect of body loosening bowel to relieve constipation, dispersing swelling and dissipating binds by using corrigent the monarch and his subjects two medicine again。Simultaneously as the effect with heat-clearing and toxic substances removing。The all medicines of this side share, and the monarch and his subjects pull together, and minister makes auxiliary altogether, have effect of cooling blood for hemostasis, clearing away heat to alleviate pain, loosening bowel to relieve constipation, dispersing swelling and dissipating binds, it is possible to effectively treat anal fissure。
Another important feature of the present invention is that this Chinese medicine preparation contains abundant nutritional labeling, more than 17 kinds are had rich in aminoacid, wherein essential amino acid has threonine, valine, methionine, isoleucine, leucine, lysine and phenylalanine, trace element containing needed by human has ferrum, chromium, copper, boron, manganese, strontium and zinc, several human body macroelement of another calcic, potassium, magnesium, phosphorus。Above nutritional labeling is all needed by human material, can effectively strengthen body immunity。
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Radix Sanguisorbae 13-17g, Fructus Sophorae 13-17g, Herba Agrimoniae 22-26g, Herba Cirsii 13-17g, Radix Cirsii Japonici 13-17g, Radix Notoginseng 10-14g, Radix Salviae Miltiorrhizae 22-26g, Herba Cistanches 22-26g, Fructus Cannabis 13-17g, Radix Et Rhizoma Rhei 7-11g, Radix Aucklandiae 10-14g, Radix Astragali 28-32g, Radix Angelicae Sinensis 16-20g, Rhizoma Cimicifugae 13-17g, Cortex Moutan 13-17g, Radix Paeoniae Rubra 13-17g, Fructus Forsythiae 13-17g, Flos Lonicerae 13-17g, Folium Isatidis 13-17g, Herba Violae 10-14g, Flos Chrysanthemi Indici 7-11g, Rhizoma Smilacis Glabrae 22-26g, Caulis Sargentodoxae 22-26g, Herba Portulacae 18-22g, Radix Pulsatillae 10-14g, Radix Arnebiae (Radix Lithospermi) 10-14g。
Wherein it is preferably: Radix Sanguisorbae 15g, Fructus Sophorae 15g, Herba Agrimoniae 24g, Herba Cirsii 15g, Radix Cirsii Japonici 15g, Radix Notoginseng 12g, Radix Salviae Miltiorrhizae 24g, Herba Cistanches 24g, Fructus Cannabis 15g, Radix Et Rhizoma Rhei 9g, Radix Aucklandiae 12g, Radix Astragali 30g, Radix Angelicae Sinensis 18g, Rhizoma Cimicifugae 15g, Cortex Moutan 15g, Radix Paeoniae Rubra 15g, Fructus Forsythiae 15g, Flos Lonicerae 15g, Folium Isatidis 15g, Herba Violae 12g, Flos Chrysanthemi Indici 9g, Rhizoma Smilacis Glabrae 24g, Caulis Sargentodoxae 24g, Herba Portulacae 20g, Radix Pulsatillae 12g, Radix Arnebiae (Radix Lithospermi) 12g。
A kind of preparation method for the Chinese medicine preparation of anal fissure is as follows:
Step one: by weight of the present invention, take the Fructus Sophorae: first take the Fructus Sophorae and put in pot and fry to heaving with slow fire, sprays into mulse (every Fructus Sophorae 100 jin, with refining hot Mel 5 jin), then fries to crust bright, tack-free for degree, and taking-up cools, and pulverizes, and crosses 200 mesh sieves, standby；
Step 2: by weight of the present invention, takes Radix Angelicae Sinensis, Rhizoma Cimicifugae, Radix Aucklandiae medical material are placed in marmite, add the water of 3 times of volumes, intense fire infusion 10-15 minute, fire infusion 10-20 minute of larding speech with literary allusions, filter liquor, repeatedly infusion three times, merge three filtrates, standby；
Step 3: by weight of the present invention, takes Radix Notoginseng, pulverizes pulverizing, crosses 200 mesh sieves, standby；
Step 4: by weight proportion of the present invention, take Radix Sanguisorbae, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra, Rhizoma Smilacis Glabrae, Caulis Sargentodoxae, the Radix Pulsatillae, Radix Arnebiae (Radix Lithospermi) medical material are placed in marmite, add the water of 8 times of volumes, after intense fire infusion 20-30 minute, add Herba Agrimoniae, Herba Cirsii, Radix Cirsii Japonici, Herba Cistanches, Flos Lonicerae, Folium Isatidis, Herba Violae, Flos Chrysanthemi Indici, Herba Portulacae and the Fructus Cannabis tied with bundle respectively, Fructus Forsythiae, intense fire infusion 10-20 minute, fire infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate for three times repeatedly, standby；
Step 5: combining step two, step 4 gained filtrate are taken after mixing it with water step one, three gained powder while hot, mixing, stir evenly, both the decoction for the treatment of anal fissure of the present invention。
Using method of the present invention: take decoction, take in meal one hour after, every day three times。
Medicine of the present invention has the effect of cooling blood for hemostasis, clearing away heat to alleviate pain, loosening bowel to relieve constipation, dispersing swelling and dissipating binds, and good analgesic effect, cheap, having no side effect, easy to use, the mode that this Chinese medicine preparation adopts treats the injury that can reduce Western medicine to patient body, alleviate the slight illness of patient, according to clinical 240 example patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 82.5%, two the course for the treatment of total effective rate 95%。
Detailed description of the invention
Embodiment one: Radix Sanguisorbae 15g, Fructus Sophorae 15g, Herba Agrimoniae 24g, Herba Cirsii 15g, Radix Cirsii Japonici 15g, Radix Notoginseng 12g, Radix Salviae Miltiorrhizae 24g, Herba Cistanches 24g, Fructus Cannabis 15g, Radix Et Rhizoma Rhei 9g, Radix Aucklandiae 12g, Radix Astragali 30g, Radix Angelicae Sinensis 18g, Rhizoma Cimicifugae 15g, Cortex Moutan 15g, Radix Paeoniae Rubra 15g, Fructus Forsythiae 15g, Flos Lonicerae 15g, Folium Isatidis 15g, Herba Violae 12g, Flos Chrysanthemi Indici 9g, Rhizoma Smilacis Glabrae 24g, Caulis Sargentodoxae 24g, Herba Portulacae 20g, Radix Pulsatillae 12g, Radix Arnebiae (Radix Lithospermi) 12g。
Embodiment two: Radix Sanguisorbae 14g, Fructus Sophorae 14g, Herba Agrimoniae 23g, Herba Cirsii 16g, Radix Cirsii Japonici 16g, Radix Notoginseng 12g, Radix Salviae Miltiorrhizae 23g, Herba Cistanches 23g, Fructus Cannabis 14g, Radix Et Rhizoma Rhei 8g, Radix Aucklandiae 13g, Radix Astragali 31g, Radix Angelicae Sinensis 17g, Rhizoma Cimicifugae 15g, Cortex Moutan 14g, Radix Paeoniae Rubra 14g, Fructus Forsythiae 16g, Flos Lonicerae 16g, Folium Isatidis 16g, Herba Violae 12g, Flos Chrysanthemi Indici 9g, Rhizoma Smilacis Glabrae 23g, Caulis Sargentodoxae 23g, Herba Portulacae 21g, Radix Pulsatillae 11g, Radix Arnebiae (Radix Lithospermi) 11g。
Embodiment three: Radix Sanguisorbae 16g, Fructus Sophorae 16g, Herba Agrimoniae 25g, Herba Cirsii 14g, Radix Cirsii Japonici 14g, Radix Notoginseng 13g, Radix Salviae Miltiorrhizae 25g, Herba Cistanches 24g, Fructus Cannabis 14g, Radix Et Rhizoma Rhei 8g, Radix Aucklandiae 11g, Radix Astragali 30g, Radix Angelicae Sinensis 17g, Rhizoma Cimicifugae 17g, Cortex Moutan 17g, Radix Paeoniae Rubra 16g, Fructus Forsythiae 16g, Flos Lonicerae 15g, Folium Isatidis 14g, Herba Violae 12g, Flos Chrysanthemi Indici 8g, Rhizoma Smilacis Glabrae 23g, Caulis Sargentodoxae 23g, Herba Portulacae 21g, Radix Pulsatillae 11g, Radix Arnebiae (Radix Lithospermi) 11g。
Patient is presented herein below and uses the clinical statistics data of medicine of the present invention:
One, physical data
Accepting out-patient 240 example for medical treatment, patient is randomly divided into observation group and each 120 examples of matched group, wherein male 40 example, women 80 example, M-F 1:2, max age 50 years old, minimal ages 14 years old, course of disease some months to several years is not etc.。Every basic documents such as two groups of patient ages, sex, courses of disease are essentially identical, no significant difference (P > 0.05)。
Two, diagnostic criteria
1. during defecation, proctalgia is obvious, and post-defecatory pain can aggravate, and often has constipation and has blood in stool on a small quantity, position, center before and after being apt to occur in。2. the shallow table lobe of anal canal skin, edge of wound is neat, and substrate is fresh, color is red, touches a tender spot substantially, and wound surface springiness is more common in a phase anal fissure。
3. having history of repeated attack, edge of wound is irregular, thickens, poor flexibility, ulcer substrate aubergine or have purulent secretion, is more common in second phase anal fissure。
4. ulcer edge hardens, and base coat colour is purplish red, has purulent secretion, and contiguous anal sinus place, upper end hypertrophy of anal papilla, there are sentry's hemorrhoid edge of wound lower end, or has subcutaneous fistula to be formed, and is more common in three phase anal fissure。
Three, Therapeutic Method:
1, observation group is according to Medications Example one of the present invention, and weighting raw materials, by the treatment of invention implementation, takes decoction, takes in meal one hour after, every day three times。It within 7 days, it is a course for the treatment of。
2, matched group adopts the outer liniment for treatment of conventional western medicine erythromycin ointment, within 7 days, is a course for the treatment of。
Four, efficacy assessment standard:
1, curing: transference cure, anal fissure heals。
2, take a turn for the better: symptom disappears substantially, and anal fissure heals substantially, occasionally have constipation bleeding。3, invalid: after treatment, symptom is without being clearly better, anal fissure wound can not all healed。
Five, therapeutic outcome statistics:
Matched group result is added up
Use the Comparison of therapeutic situation of this Chinese medicine preparation two courses for the treatment of of two groups of patients
Wherein: total effective rate=cure rate+improvement rate
By contrasting the treatment total effective rate of two groups of patients it appeared that observation group is apparently higher than matched group, thus illustrate, Chinese medicine of the present invention has good clinical effectiveness in treatment anal fissure, the cure rate for the treatment of can be effectively improved, effect is notable, cheap, have no adverse reaction and any toxic and side effects, there is wide market application foreground。
Model case and curative effect:
Case one, patient Wang, female, 26 years old, people from Qingdao City, comes here and goes to a doctor on January 20th, 2013。Main suit: having during stool and serious after an action of the bowels burn sample, it is main for wiping blood after an action of the bowels on paper, and color is scarlet, will not occur spray blood as hemorrhoid, simultaneously with constipation symptom, removes examination in hospital and to do biopsy diagnosis is anal fissure。Through adopting the outer liniment for treatment pain relief of erythromycin ointment, but do not cure。Later because once eating maror, symptom occurs again, then here treatment, adopt made preparation in the embodiment of the present invention one, and selected preparation method, symptom goes down, and after medication 5 days, pain disappears, affected part recovers good, continues medication 6 days, thoroughly cures, and Effect of follow-up visit by telephone does not recur half a year。
Case two, patient Lee, female, 32 years old, people from Linyi, Shandong。Coming here on May 14th, 2014 to go to a doctor, patient's chief complaint is as follows: have cutting pains serious after an action of the bowels during stool, and it is main for wiping blood after an action of the bowels on paper, and color is scarlet, will not occur spray blood as hemorrhoid, simultaneously with constipation symptom, is diagnosed as anal fissure。Adopting made preparation in the embodiment of the present invention one and selected preparation method, symptom goes down, and pain slightly alleviates, and after medication 7 days, affected part recovers good, thoroughly cures, and Effect of follow-up visit by telephone does not recur half a year。
Claims (4)
1. the Chinese medicine preparation for anal fissure, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Radix Sanguisorbae 13-17g, Fructus Sophorae 13-17g, Herba Agrimoniae 22-26g, Herba Cirsii 13-17g, Radix Cirsii Japonici 13-17g, Radix Notoginseng 10-14g, Radix Salviae Miltiorrhizae 22-26g, Herba Cistanches 22-26g, Fructus Cannabis 13-17g, Radix Et Rhizoma Rhei 7-11g, Radix Aucklandiae 10-14g, Radix Astragali 28-32g, Radix Angelicae Sinensis 16-20g, Rhizoma Cimicifugae 13-17g, Cortex Moutan 13-17g, Radix Paeoniae Rubra 13-17g, Fructus Forsythiae 13-17g, Flos Lonicerae 13-17g, Folium Isatidis 13-17g, Herba Violae 10-14g, Flos Chrysanthemi Indici 7-11g, Rhizoma Smilacis Glabrae 22-26g, Caulis Sargentodoxae 22-26g, Herba Portulacae 18-22g, Radix Pulsatillae 10-14g, Radix Arnebiae (Radix Lithospermi) 10-14g。
2. the Chinese medicine preparation for anal fissure according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Radix Sanguisorbae 15g, Fructus Sophorae 15g, Herba Agrimoniae 24g, Herba Cirsii 15g, Radix Cirsii Japonici 15g, Radix Notoginseng 12g, Radix Salviae Miltiorrhizae 24g, Herba Cistanches 24g, Fructus Cannabis 15g, Radix Et Rhizoma Rhei 9g, Radix Aucklandiae 12g, Radix Astragali 30g, Radix Angelicae Sinensis 18g, Rhizoma Cimicifugae 15g, Cortex Moutan 15g, Radix Paeoniae Rubra 15g, Fructus Forsythiae 15g, Flos Lonicerae 15g, Folium Isatidis 15g, Herba Violae 12g, Flos Chrysanthemi Indici 9g, Rhizoma Smilacis Glabrae 24g, Caulis Sargentodoxae 24g, Herba Portulacae 20g, Radix Pulsatillae 12g, Radix Arnebiae (Radix Lithospermi) 12g。
3. the Chinese medicine preparation for anal fissure according to claim 1 and 2, it is characterised in that: described Chinese medicine preparation is decoction。
4. the preparation method for the Chinese medicine preparation of anal fissure, it is characterized in that, preparation method is as follows: step one: by weight of the present invention, take the Fructus Sophorae: first takes the Fructus Sophorae and puts the interior slow fire stir-fry of pot to heaving, sprays into mulse (every Fructus Sophorae 100 jin, with refining hot Mel 5 jin), frying bright, tack-free to crust again is degree, and taking-up cools, and pulverizes, cross 200 mesh sieves, standby；Step 2: by weight of the present invention, takes Radix Angelicae Sinensis, Rhizoma Cimicifugae, Radix Aucklandiae medical material are placed in marmite, add the water of 3 times of volumes, intense fire infusion 10-15 minute, fire infusion 10-20 minute of larding speech with literary allusions, filter liquor, repeatedly infusion three times, merge three filtrates, standby；Step 3: by weight of the present invention, takes Radix Notoginseng, pulverizes pulverizing, crosses 200 mesh sieves, standby；Step 4: by weight proportion of the present invention, take Radix Sanguisorbae, Radix Salviae Miltiorrhizae, Radix Et Rhizoma Rhei, the Radix Astragali, Cortex Moutan, Radix Paeoniae Rubra, Rhizoma Smilacis Glabrae, Caulis Sargentodoxae, the Radix Pulsatillae, Radix Arnebiae (Radix Lithospermi) medical material are placed in marmite, add the water of 8 times of volumes, after intense fire infusion 20-30 minute, add Herba Agrimoniae, Herba Cirsii, Radix Cirsii Japonici, Herba Cistanches, Flos Lonicerae, Folium Isatidis, Herba Violae, Flos Chrysanthemi Indici, Herba Portulacae and the Fructus Cannabis tied with bundle respectively, Fructus Forsythiae, intense fire infusion 10-20 minute, fire infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate for three times repeatedly, standby；Step 5: combining step two, step 4 gained filtrate are taken after mixing it with water step one, three gained powder while hot, mixing, stir evenly, both the decoction for the treatment of anal fissure of the present invention。
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105853976A (en) * | 2016-05-04 | 2016-08-17 | 王兴山 | Chinese herbal medicine preparation for rectovesical fistula and preparation method of Chinese herbal medicine preparation |
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