CN102579807B - Chinese medicine composition for treating dental ulcer - Google Patents

Chinese medicine composition for treating dental ulcer Download PDF

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Publication number
CN102579807B
CN102579807B CN 201210086264 CN201210086264A CN102579807B CN 102579807 B CN102579807 B CN 102579807B CN 201210086264 CN201210086264 CN 201210086264 CN 201210086264 A CN201210086264 A CN 201210086264A CN 102579807 B CN102579807 B CN 102579807B
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parts
chinese medicine
medicine composition
rhizoma
ulcer
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CN102579807A (en
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崔景明
董兴红
赵海玲
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Haimen Linjiang Biological Medicine Science And Technology Pioneer Park Co Ltd
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Abstract

A Chinese medicine composition for treating dental ulcer is prepared by selfheal, drymoglossum piloselloides presl, chinarue, honeysuckle, radix ophiopogonis, rhubarb, poria cocos, dogwood, cimicifugae foetidae, indigo naturalis, pinellia ternate and semen cuscutae. The Chinese medicine composition can be used for treating dental ulcer in clinical application.

Description

A kind of Chinese medicine composition for the treatment of oral ulcer
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of oral ulcer.
Background technology
Oral ulcer, oral mucosa painful, recurrent, single-shot or multiple ulcer, it is modal a kind of disease in the oral mucosal disease, be apt to occur in by rear portion, oral cavity, cheek, the pharynx, hard palate or soft palate intersection, its clinical symptoms is shown effect as main repeatedly take causalgia, ulcer, the primary disease cause of disease is unclear, and the someone thinks wound, chemical substance stimulation, endocrine alteration, psychentonia and anxious state of mind, and various infection may be inducement.
Motherland's medical science thinks that primary disease is many by due to accumulation of heat in the heart and spleen, flaming up of stomach-fire, hyperactivity of fire caused by deficiency of YIN, the insufficiency of the spleen leading to overabundance of dampness, is referred to as " aphtha ", " aphtha ", how because of the heresy of affection due to external wind and heat, the oral cavity is unclean, and damaged in mouthful, evil poison enters interior relevant, in in close relations with the visceral dysfunction such as accumulation of heat in the heart and spleen flaming up of heart-fire, cause hyperactivity of fire caused by deficiency of YIN, pyretic toxicity is burnt bright, and inner clip is damp and hot, upper steaming and mouth, the unsuccessful heart spleen that undermines of temperament and interest all causes oral ulcer.
Summary of the invention
The Chinese medicine composition of the treatment oral ulcer that the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopts Spica Prunellae, newspaper tree lotus, Herba Boenninghauseniae, Flos Lonicerae, Radix Ophiopogonis, Radix Et Rhizoma Rhei, Poria, Fructus Corni, Rhizoma Cimicifugae, Indigo Naturalis, the Rhizoma Pinelliae, Semen Cuscutae is made, according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: Spica Prunellae 40-60 part, newspaper tree lotus 40-60 part, Herba Boenninghauseniae 20-40 part, Flos Lonicerae 20-40 part, Radix Ophiopogonis 20-40 part, the 10-20 of Radix Et Rhizoma Rhei part, Poria 10-20 part, Fructus Corni 10-20 part, Rhizoma Cimicifugae 10-20 part, Indigo Naturalis 10-20 part, Rhizoma Pinelliae 10-20 part, Semen Cuscutae 10-20 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 50 parts of Spica Prunellaes, 50 parts in newspaper tree lotus, 30 parts of Herba Boenninghauseniaes, 30 parts of Flos Loniceraes, 30 parts of Radix Ophiopogonis, 15 parts in Radix Et Rhizoma Rhei, 15 parts in Poria, 15 parts of Fructus Corni, 15 parts of Rhizoma Cimicifugaes, 15 parts of Indigo Naturaliss, 15 parts of the Rhizoma Pinelliaes, 15 parts of Semen Cuscutae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Spica Prunellae: hot, bitter, cold.Return liver, gallbladder meridian.Clearing away liver-fire, Disperse hepatic depression.Be used for that conjunctival congestion and swelling pain, headache are dizzy, scrofula goiter etc.
Drymoglossum Herba Drymoglossi: sweet, light, little cold.Return liver, lung meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, hemostasis.Be used for jaundice due to damp-heat, conjunctival congestion and swelling pain, parotitis, lymphadenitis, traumatic injury.
Herba Boenninghauseniae: suffering; Bitter; Cool in nature; Mild toxicity.Lung; The stomach warp.Dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing, promoting flow of QI and blood.Be used for flu, tonsillitis, bronchitis, pneumonia, pyelonephritis, stomachache abdominal distention, thromboangiitis obliterans, lumbago, traumatic injury etc.
Flos Lonicerae: sweet, cold, return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Be used for carbuncle furuncle, toxic-heat and blood stasis.
Radix Ophiopogonis: sweet, little hardship, be slightly cold.Return lung, stomach, heart channel.Nourishing YIN and moistening the lung, reinforcing stomach reg fluid, relieving restlessness clears away heart-fire.Cure mainly dryness of the lung dry cough, the deficiency of YIN, Tianjin wound is thirsty, the cards such as vexed insomnia.
Radix Et Rhizoma Rhei: bitter, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, the effect of detoxifcation.Be used for the excess-heat constipation, the accumulation of heat feeling of stuffiness in chest, damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria, conjunctival congestion etc.
Poria: sweet, light, flat.GUIXIN, spleen, lung, kidney channel.Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Be used for dysuria, the edema distension, the phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite is had loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.
Fructus Corni: acid, tepor, return liver, kidney channel.Liver and kidney tonifying, convergence are taken off admittedly.Cure mainly and have a dizzy spell, the cards such as deafness and tinnitus.
Rhizoma Cimicifugae: hot, sweet, be slightly cold, return lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.Be used for headache due to pathogenic wind-heat, measles without adequate eruption, laryngopharynx swelling and pain, collapse of QI, chronic diarrhea proctoptosis, metrostaxis etc.
Indigo Naturalis: salty, cold.Return liver, lung, stomach warp.Heat-clearing and toxic substances removing, cooling blood for hemostasis, purging liver-fire.Be used for the epidemic febrile disease maculopapulae due to toxic heat, heat in blood is spitted blood, epistaxis, spitting of blood, liver-heat infantile convulsion, liver-fire invading the lung cough, laryngopharynx swelling and pain etc.
The Rhizoma Pinelliae: hot, temperature, poisonous.Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Cure mainly the cough with asthma abundant expectoration, feeling of oppression and fullness in the chest and epigastrium, it is dizzy to have a headache etc.
Semen Cuscutae: hot, sweet, put down, return the liver,kidney,spleen warp.The kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the tire stopping leak.Be used for soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst stranguria with turbid discharge, the enuresis etc.
Spica Prunellae of the present invention, newspaper tree lotus, Herba Boenninghauseniae, Flos Lonicerae, Radix Et Rhizoma Rhei, Rhizoma Cimicifugae, Indigo Naturalis heat-clearing and toxic substances removing, detumescence, dispelling wind and heat pathogens, purging liver-fire are invigorated blood circulation in hemostasis; Radix Ophiopogonis, Poria, Fructus Corni, the Rhizoma Pinelliae, Semen Cuscutae nourishing YIN and moistening the lung, liver and kidney tonifying, it is strong that The spleen is closely related to the stomach, and compatibility uses, and promotes the very fast healing of local ulcer, reaches the purpose for the treatment of oral ulcer.
Chinese medicine composition of the present invention is used in 2006 to 2010 clinical observation oral ulcer disease 150 routine patients, and clinical report is as follows:
1, physical data
Among the 150 routine patients, women's 80 examples, male's 70 examples, at minimum 20 years old of age, maximum 79 years old, the course of disease was many at 3 months to 4 years, 32.6 years old mean age.
2, diagnostic criteria
Reference " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":
1. the ulcer of single or several diameters 3~5mm occurs with oral mucosa, scorching hot pain is cardinal symptom;
2. onset is very fast, healing in general about 7 days, if down here, then the course of disease prolongs, rear normal easily recurrence;
3. examination of mouth: stomatocace is shown shallow, and is circular or oval, 1~2 at least of quantity, and more than 10 at most, the surface has faint yellow secretions to adhere to, and mucosa is mostly congested around the ulcer.
3, Therapeutic Method
3.1 prescription: Spica Prunellae 50g, newspaper tree lotus 50g, Herba Boenninghauseniae 30g, Flos Lonicerae 30g, Radix Ophiopogonis 30g, the 15g of Radix Et Rhizoma Rhei, Poria 15g, Fructus Corni 15g, Rhizoma Cimicifugae 15g, Indigo Naturalis 15g, Rhizoma Pinelliae 15g, Semen Cuscutae 15g.
3.2 preparation method: said medicine routinely technique is made decoction.
3.3 instructions of taking: each 1 dose, every day 2 times, 5 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 reference " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":
Cure: the oral ulcer healing, local without sense of discomfort;
Take a turn for the better: although recurrence is arranged during aphtha, quantity reduces, and degree alleviates;
Do not heal: aphtha symptom and ulcer are without significant change.
4.2 result: among the 150 routine patients, cure 95 examples (64%), 50 examples that take a turn for the better (33%), 5 examples (3%) that do not heal, total effective rate is 97%.
5, model case
5.1 the man, 52 years old, oral erosion more than 3 years showed effect, rises one after another, once takes Chinese and western drugs and intramuscular injection interferon etc. repeatedly, and the state of an illness is without being clearly better.See when medical that there is the ulcer of two Semen Viciae fabae sample sizes on the tongue body both sides, intermediate recess, the surface is covered by white pod membrane, both sides a plurality of aphthas that also the sporadically appear oral cavity in, surperficial greyish white, ambient color is light red.Body of the tongue is light red, and thin white fur of tongue is slightly greasy, deep-thready pulse.Take the Chinese medicine composition that the present invention treats oral ulcer and treat, treat 1 course for the treatment of after, the patient is in high spirits, ulcer improves gradually, rear taking medicine continuously 1 course for the treatment of, not again recurrence in 1 year is followed up a case by regular visits in recovery from illness.
5.2 the man, 36 years old, stomatocace was 2 years repeatedly, mostly was and was dispersed in distribution, isolated circular or oval little fester, and diameter 2-3mm, red and swollen, causalgia, 1 all left and right sides ulcer heals voluntarily.The time larger area stomatocace is arranged, diameter is about 5mm, number is 1 or 2, about 2-3 week could heal.Taken the Chinese medicine composition that the present invention treats oral ulcer, 2 courses for the treatment of, disease obtains recovery from illness, follows up a case by regular visits to not again recurrence in 1 year.
5.3 the woman, 26 years old, recently, festered in the oral cavity repeatedly, and recur once or for several times, be dispersed in lingual surface, gingiva with a plurality of ulcer general January, local pain, impact feed.Red tongue, yellow and thin fur, wiry and frequent pulse.Taken the Chinese medicine composition that the present invention treats oral ulcer, after 1 course for the treatment of, oral ulcer is surplus 1 place only, continues to take 1 course for the treatment of, and disease obtains recovery from illness, follows up a case by regular visits to not again recurrence in 1 year.
5.4 the woman, 69 years old, oral cavity and 2 weeks of gingiva many places ulcer, the large about 5mm of person, the about 2mm of little person, local scorching hot, pain accompanies that the xerostomia eye is dried, insomnia and dreamful sleep, soreness of the waist and knees, dizziness and tinnitus.Taken the Chinese medicine composition that the present invention treats oral ulcer, after 2 courses for the treatment of, disease obtains recovery from illness, follows up a case by regular visits to not again recurrence in 1 year.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and following this embodiment only for explanation the present invention to the present invention without limits.
Embodiment 1, a kind of Chinese medicine composition for the treatment of oral ulcer, and it is to be made by following raw material medicaments: Spica Prunellae 40g, newspaper tree lotus 40g, Herba Boenninghauseniae 20g, Flos Lonicerae 20g, Radix Ophiopogonis 20g, the 10g of Radix Et Rhizoma Rhei, Poria 10g, Fructus Corni 10g, Rhizoma Cimicifugae 10g, Indigo Naturalis 10g, Rhizoma Pinelliae 10g, Semen Cuscutae 10g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of oral ulcer, and it is to be made by following raw material medicaments: Spica Prunellae 50g, newspaper tree lotus 50g, Herba Boenninghauseniae 30g, Flos Lonicerae 30g, Radix Ophiopogonis 30g, the 15g of Radix Et Rhizoma Rhei, Poria 15g, Fructus Corni 15g, Rhizoma Cimicifugae 15g, Indigo Naturalis 15g, Rhizoma Pinelliae 15g, Semen Cuscutae 15g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of oral ulcer, and it is to be made by following raw material medicaments: Spica Prunellae 60g, newspaper tree lotus 60g, Herba Boenninghauseniae 40g, Flos Lonicerae 40g, Radix Ophiopogonis 40g, the 20g of Radix Et Rhizoma Rhei, Poria 20g, Fructus Corni 20g, Rhizoma Cimicifugae 20g, Indigo Naturalis 20g, Rhizoma Pinelliae 20g, Semen Cuscutae 20g.

Claims (2)

1. Chinese medicine composition for the treatment of oral ulcer is characterized in that being comprised of following crude drug:
Spica Prunellae 40-60 part, Drymoglossum Herba Drymoglossi 40-60 part, Herba Boenninghauseniae 20-40 part, Flos Lonicerae 20-40 part, Radix Ophiopogonis 20-40 part, the 10-20 of Radix Et Rhizoma Rhei part, Poria 10-20 part, Fructus Corni 10-20 part, Rhizoma Cimicifugae 10-20 part, Indigo Naturalis 10-20 part, Rhizoma Pinelliae 10-20 part, Semen Cuscutae 10-20 part.
2. Chinese medicine composition according to claim 1 is characterized in that being comprised of following crude drug:
50 parts of Spica Prunellaes, 50 parts of Drymoglossum Herba Drymoglossis, 30 parts of Herba Boenninghauseniaes, 30 parts of Flos Loniceraes, 30 parts of Radix Ophiopogonis, 15 parts in Radix Et Rhizoma Rhei, 15 parts in Poria, 15 parts of Fructus Corni, 15 parts of Rhizoma Cimicifugaes, 15 parts of Indigo Naturaliss, 15 parts of the Rhizoma Pinelliaes, 15 parts of Semen Cuscutae.
CN 201210086264 2012-03-21 2012-03-21 Chinese medicine composition for treating dental ulcer Expired - Fee Related CN102579807B (en)

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104187470B (en) * 2014-08-12 2016-05-25 黄太锋 A kind of auricularia auriculajudae cucumber congee that can alleviate canker sore
CN105816651A (en) * 2016-04-28 2016-08-03 彭晓玲 Preparation for treating oral ulcer and preparation method and medicine of preparation
CN106166246A (en) * 2016-08-18 2016-11-30 北华大学 A kind of Chinese medicine formula treating recurrent oral ulceration and preparation method thereof
CN107854577A (en) * 2017-11-28 2018-03-30 李妍 A kind of preparation method of spraying agent for ulcer of oral cavity

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361870A (en) * 2008-10-13 2009-02-11 祝亮环 Traditional Chinese medicine combination for preventing infection after mouth operation
CN101757212A (en) * 2008-11-07 2010-06-30 贠钦亮 Traditional Chinese medicine powder for treating dental ulcer
CN102100744A (en) * 2009-12-18 2011-06-22 朱鸿龙 Chinese medicine composition for treating mouth ulcer
CN102228531A (en) * 2011-07-14 2011-11-02 黎红 Chinese medicinal composition for treating dental ulcers

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361870A (en) * 2008-10-13 2009-02-11 祝亮环 Traditional Chinese medicine combination for preventing infection after mouth operation
CN101757212A (en) * 2008-11-07 2010-06-30 贠钦亮 Traditional Chinese medicine powder for treating dental ulcer
CN102100744A (en) * 2009-12-18 2011-06-22 朱鸿龙 Chinese medicine composition for treating mouth ulcer
CN102228531A (en) * 2011-07-14 2011-11-02 黎红 Chinese medicinal composition for treating dental ulcers

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