A kind of Chinese medicine composition for the treatment of allergic asthma
Technical field
The invention belongs to the technical field of the medicine for the treatment of allergic asthma, refer to a kind of Chinese medicine composition being used for the treatment of allergic asthma especially.
Background technology
Allergic asthma is that body fight originality or nonantigenic stimulate the reactive disease excessively increased of a kind of trachea-bronchial epithelial cell caused.Allergic asthma is a kind of chronic respiratory system diseases that global incidence is the highest, and it is a kind of more obstinate disease, if ignore treatment, and can with lifelong.Premonitory symptom is had as sneeze, watery nasal discharge, cough, uncomfortable in chest etc. before allergic asthma outbreak, as processed not in time, asthma can be there is because bronchial obstruction increases the weight of, severe patient can be forced to take seat or in orthopnea,, even there is cyanosis etc. in dry cough or cough up a large amount of white foam expectorant, but generally can voluntarily or with alleviating voluntarily or with after the treatments such as suppressing panting calming medicine, some patient can again show effect after alleviation a few hours, even causes status asthmaticus.
Allergic asthma frequently-occurring disease is childhood, and patient often has the atopy body constitution to Cucumber allergy, can have obvious allergen exposure history, or relevant with season; Many morbidities when night or morning rise, sickness rate 1%-11%; In recent years, its sickness rate, mortality rate have the trend increased.Because the allergic asthma cause of disease is complicated, pathogenesis is still not clear, and lacks effective medicine.
At present, clinical treatment allergic asthma, except instrucion patient is away from except anaphylactogen, main use hormone and anti-inflammatory drug, with the frequency of Control of asthma outbreak and cycle, but these medicines have obvious toxic and side effects, and, often recur very soon after drug withdrawal.Many TCM investigation persons also develop the Chinese medicine of some treatment allergic asthmas, these also Chinese medicine exist and take inconvenience, damage is caused to the intestines and stomach of patient, and, take effect slow, add the misery of patient.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of allergic asthma, solve in prior art that the drug side effect for the treatment of allergic asthma is large, the problem of weak curative effect and easily recurrence.
A kind of Chinese medicine composition for the treatment of allergic asthma of the present invention, it is mainly realized by the following technical programs:
Chinese medicine composition of the present invention, the raw material comprising following weight portion is made: Bal(n)phyllia sp. 10-15 part, old Caulis Perillae 6-12 part, Rhizoma Polygonati 10-15 part, Radix Dipsaci 10-15 part, Herba Ephedrae (processed) 6-12 part, Radix Scutellariae 10-15 part, Cortex Mori 6-12 part, Periostracum Cicadae 3-6 part, coltsfoot 10-15 part, Rhizoma Zingiberis 10-15 part, Radix Aconiti Lateralis Preparata 6-12 part, Flos Magnoliae 3-6 part, Fructus Xanthii 6-12 part, Fructus Viticis Negundo 10-15 part, Rhizoma Belamcandae 6-12 part, Herba Plantaginis 6-12 part, Radix Saposhnikoviae 6-12 part, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 20-40 part, Folium Elaeagni 10-15 part, Ramulus Cinnamomi 6-12 part, Cortex Eucommiae 6-12 part, PINGDIMU 10-15 part, Folium Mahoniae 6-12 part, Herba Artemisiae Scopariae 6-12 part, Flos Chrysanthemi Indici 6-12 part, Fructus Atriplicis Sibiricae 6-12 part.
Chinese medicine composition compatibility of the present invention is scientific and reasonable, and drug effect complements each other, and medicine source is wide, is cheaply easy to get; Relieved oedema or abdominal distension through diuresis or purgation by lung qi dispersing, warming spleen and stomach for dispelling cold, warming the kidney to invigorate YANG, invigorating the spleen and benefiting QI, dispersing the stagnated live-QI to relieve the stagnation of QI, reach heat radiation lung heat clearing, relieving cough and asthma, blood stasis dispelling sending down the abnormal ascending QI, antiphlogistic antibacterial, eliminating pathogenic factor for supporting vital QI effect; Meanwhile, also there is the effect strengthening body immunity, fundamentally can cure allergic asthma, reach the object for the treatment of both the principal and secondary aspects of a disease; Treatment for allergic asthma has instant effect, stable curative effect, does not recur, has no side effect.
In Chinese medicine composition of the present invention, Bal(n)phyllia sp.: property is sweet, salty in the mouth, tepor; Return lung, kidney, stomach warp; There is warming the lung, tonifying YANG, effect of lactogenesis; Cure mainly lung cold chronic cough, asthenia cough with asthma, impotence and premature ejaculation, emission, cold arthralgia of loins and legs, galactostasis.
In Chinese medicine composition of the present invention, old Caulis Perillae: property is pungent, sweet in the mouth, tepor; Enter spleen, stomach, lung three warp; Have and regulate the flow of vital energy, Shu Yu, pain relieving, antiabortive effect; Cure mainly the stagnation of QI, dyspepsia, chest and diaphragm painful abdominal mass is vexed, epigastric pain, and nausea is got along well.
In Chinese medicine composition of the present invention, Rhizoma Polygonati: sweet in the mouth, property is put down; Enter lung, spleen, kidney channel; There is nourishing kidney lung moistening, effect of invigorating the spleen and replenishing QI; Cure mainly lung-dryness syndrome due to deficiency of YIN, dry cough expectorant is few, polydipsia of quenching one's thirst; Weakness of the spleen and stomach, deficiency of spleen-QI or deficiency of spleen-YIN; Deficiency of kidney essence, soreness of the waist and knees, early whitening of beard and hair.
In Chinese medicine composition of the present invention, Radix Dipsaci: bitter in the mouth, property is pungent, tepor; Return liver, kidney channel; There is invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous injured, effect of only metrorrhagia; Cure mainly aching pain in waist and back, podomere flaccidity syndrome and arthralgia syndrome, fall flutter wound, damage muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer swell.
In Chinese medicine composition of the present invention, Herba Ephedrae (processed): property is pungent, micro-hardship, taste temperature; Return lung, urinary bladder channel; There is effect of diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema; Cure mainly exterior syndrome due to wind-cold, breath with cough card, edema etc.
In Chinese medicine composition of the present invention, Radix Scutellariae: sweet in the mouth, tepor; Return spleen, lung meridian; There is benefit and defend consolidating superficial resistance, tonifying Qi and lifting yang, promoting pus discharge and tissue regeneration strengthening, effect of inducing diuresis to remove edema; Cure mainly the deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, spontaneous sweating, blood deficiency and yellow complexion, carbuncle of yin nature is unrestrained swollen, and deficiency of vital energy edema, interior-heat is quenched one's thirst.
In Chinese medicine composition of the present invention, Cortex Mori: sweet in the mouth, cold in nature; Enter lung meridian; There is eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema, repair effect of cicatrix; Cure mainly lung-heat cough with asthma, the edema of the face, the diseases such as dysuria.
In Chinese medicine composition of the present invention, Periostracum Cicadae: sweet in the mouth, property are pungent, micro-cool; Return lung, Liver Channel; Have dispelling wind and heat pathogens, rash sore-throat relieving, improving acuity of vision and removing nebula, the effect of expellingging wind and relieving convulsion, cures mainly anemopyretic cold, cough, dizzy, measles without adequate eruption, pharyngalgia hoarseness, cataract, pruritus before wind, pediatric epilepsy scared, night cry, tetanus.
In Chinese medicine composition of the present invention, coltsfoot: property is pungent, taste temperature; Return lung meridian; There is preventing phlegm from forming and stopping coughing, the antitussive therapeutic method to keep the adverse QI flowing downwards, effect that lung moistening is eliminated the phlegm; Cure mainly cough, asthma, consumptive lung disease, coughs the diseases such as blood of spitting, and is particularly suitable for chronic cough of deficiency lung more than.
In Chinese medicine composition of the present invention, Rhizoma Zingiberis: acrid in the mouth, hot in nature; Return spleen, stomach, the heart, lung meridian; There is warming spleen and stomach for dispelling cold, recuperating depleted YANG promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention effect; Cure mainly coldness and pain in the epigastrium, vomiting, have loose bowels, YANG-depletion is fainted inverse, and cold fluid-retention is breathed with cough, arthralgia due to cold-dampnes.
In Chinese medicine composition of the present invention, Radix Aconiti Lateralis Preparata: property is pungent, sweet in the mouth, hot greatly; GUIXIN, kidney, spleen channel; There is recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, effect of dispersing cold for relieving pain; Cure mainly excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea, it is inverse to faint, cold extremities faint pulse, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, sexual impotence, cold womb, and deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor.
In Chinese medicine composition of the present invention, Flos Magnoliae: acrid in the mouth, warm in nature; Enter lung meridian, stomach warp; There is dispersing wind and cold, effect of clearing the nasal passage; Cure mainly cold stuffy nasal obstruction, nasosinusitis headache.
In Chinese medicine composition of the present invention, Fructus Xanthii: bitter in the mouth, property are pungent, tepor; Enter lung, Liver Channel; There is effect of dispersing wind-cold, clearing the nasal passage, wind-damp dispelling and pain relieving; Control headche due to wind-cold, nasal sinusitis, toothache, anemofrigid-damp arthralgia, limb pain twin, mange, pruritus.
In Chinese medicine composition of the present invention, Fructus Viticis Negundo: acrid in the mouth, warm in nature; Return lung, stomach, Liver Channel; There is expelling pathogenic wind from the body surface, relieving cough and asthma, regulate the flow of vital energy and help digestion, effect of pain relieving; Cure mainly Common Cold, cough, asthma, stomachache acid regurgitation, dyspepsia, food stagnation dysentery, cholecystitis, cholelithiasis, hernia.
In Chinese medicine composition of the present invention, Rhizoma Belamcandae: bitter in the mouth, cold in nature; Enter lung, Liver Channel; There is heat-clearing and toxic substances removing, throat, effect of expectorant saliva; Cure mainly laryngopharynx swelling and pain, expectorant dyspnea due to attack of the lung by retained fluid is coughed.
In Chinese medicine composition of the present invention, Herba Plantaginis: property is sweet, lightly seasoned, be slightly cold; Return lung, liver, kidney, urinary bladder channel; There is clearing away heat and promoting diuresis, effect that eliminating dampness by diuresis antidiarrheal, improving eyesight are eliminated the phlegm; Cure mainly dysuria, stranguria with turbid discharge leukorrhagia, edema distension, heat-damp in summer dysentery, conjunctival congestion are hidden from view, expectorant heat syndrome cough is breathed heavily.
In Chinese medicine composition of the present invention, Radix Saposhnikoviae: acrid in the mouth, property are sweet, tepor; Return bladder, liver, spleen channel; There is expelling pathogenic wind from the body surface, effect that removing dampness to relieve pain, relieving convulsion are jerked surely; Cure mainly diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.
In Chinese medicine composition of the present invention, Lagenaria siceraria(Molina) Standl.var.depressa Ser.: bitter in the mouth, warm in nature; Enter kidney channel; There is warming the kidney to invigorate YANG, effect of expelling cold and dampness; Cure mainly warming the kidney to invigorate YANG, cold expelling dries pain relieving.
In Chinese medicine composition of the present invention, Folium Elaeagni: sour in the mouth, property are flat; Enter lung meridian; There is relieving cough and asthma, hemostasis, effect of removing toxic substances; Cure mainly cough due to deficiency of the lung, asthma, hemoptysis, spit blood, traumatic hemorrhage, carbuncle, swelling and pain of hemorrhoid.
In Chinese medicine composition of the present invention, Ramulus Cinnamomi: property is pungent, sweet in the mouth, tepor; GUIXIN, lung, urinary bladder channel; There is diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, effect of dispersing cold for relieving pain; Cure mainly exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea, lump in the abdomen lumps, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria.
In Chinese medicine composition of the present invention, the Cortex Eucommiae: sweet in the mouth, warm in nature; Return liver, kidney channel; There is invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect; Cure mainly spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, vaginal bleeding during pregnancy for falling, frequent fetal movement, hypertension.
In Chinese medicine composition of the present invention, PINGDIMU: property is flat, acrid in the mouth, micro-hardship; Return lung, Liver Channel; There is preventing phlegm from forming and stopping coughing, dampness removing, the effect of invigorating blood circulation; Cure mainly new chronic cough to cough, sputum mixed with blood, jaundice, edema, stranguria, leucorrhea, amenorrhea dysmenorrhea, rheumatic arthralgia, traumatic injury, painful and swollen testis.
In Chinese medicine composition of the present invention, Folium Mahoniae: bitter in the mouth, cool in nature; Enter liver, kidney channel; There is clearind deficient heat, liver and kidney tonifying, effect of wind-damp dispelling; Cure mainly hectic fever due to deficiency of YIN, cough spitting of blood, has a dizzy spell, soreness of the waist and knees, rheumatic arthralgia, vitiligo.
In Chinese medicine composition of the present invention, Herba Artemisiae Scopariae: bitter in the mouth, property be pungent, be slightly cold; Return spleen, stomach, liver, gallbladder meridian; There is clearing away damp-heat, effect of jaundice eliminating subcutaneous ulcer; Cure mainly jaundice oliguria, eczema pruritus, infectious jaundice type hepatitis.
In Chinese medicine composition of the present invention, Flos Chrysanthemi Indici: property is pungent, bitter in the mouth, be slightly cold; Return lung, Liver Channel; There is heat-clearing and toxic substances removing, effect of dispelling wind suppressing the hyperactive liver; Cure mainly furuncle, carbuncle, erysipelas, eczema, dermatitis, anemopyretic cold, laryngopharynx swelling and pain, hypertension.
In Chinese medicine composition of the present invention, Fructus Atriplicis Sibiricae: property is pungent, bitter in the mouth, tepor; Enter liver, lung meridian; There is effect of dispersing the stagnated live-QI to relieve the stagnation of QI, dispelling pathogenic wind for improving eyesight, promoting flow of QI and blood and dispelling wind for relieving itching.
Preferably, Chinese medicine composition of the present invention, the raw material comprising following weight portion is made: Bal(n)phyllia sp. 12 parts, old Caulis Perillae 9 parts, Rhizoma Polygonati 12 parts, Radix Dipsaci 12 parts, Herba Ephedrae (processed) 9 parts, Radix Scutellariae 12 parts, Cortex Mori 9 parts, Periostracum Cicadae 4.5 parts, coltsfoot 12 parts, Rhizoma Zingiberis 12 parts, Radix Aconiti Lateralis Preparata 9 parts, Flos Magnoliae 4.5 parts, Fructus Xanthii 9 parts, Fructus Viticis Negundo 12 parts, Rhizoma Belamcandae 9 parts, Herba Plantaginis 9 parts, Radix Saposhnikoviae 9 parts, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 30 parts, Folium Elaeagni 12 parts, Ramulus Cinnamomi 9 parts, the Cortex Eucommiae 9 parts, PINGDIMU 12 parts, Folium Mahoniae 9 parts, Herba Artemisiae Scopariae 9 parts, Flos Chrysanthemi Indici 9 parts, Fructus Atriplicis Sibiricae 9 parts.
Chinese medicine composition of the present invention by comprise Bal(n)phyllia sp., old Caulis Perillae, Rhizoma Polygonati, Radix Dipsaci, Herba Ephedrae (processed), Radix Scutellariae, Cortex Mori, Periostracum Cicadae, coltsfoot, Rhizoma Zingiberis, Radix Aconiti Lateralis Preparata, Flos Magnoliae, Fructus Xanthii, Fructus Viticis Negundo, Rhizoma Belamcandae, Herba Plantaginis, Radix Saposhnikoviae, Lagenaria siceraria(Molina) Standl.var.depressa Ser., Folium Elaeagni, Ramulus Cinnamomi, the Cortex Eucommiae, PINGDIMU, Folium Mahoniae, Herba Artemisiae Scopariae, Flos Chrysanthemi Indici, Fructus Atriplicis Sibiricae at least two ten Six-element herbal raw materials formulated, its drug effect brings out the best in each other, through focus depths, inside of human body function is comprehensively nursed one's health thoroughly, significantly reduces patient's economy and psychological burden.Through clinical verification, the cure rate of traditional Chinese medicine composition for treating allergic asthma of the present invention is high, and total effective rate reaches 99%, efficacy stability.
Particularly, in Chinese medicine composition of the present invention, the dosage form of described Chinese medicine composition is the one in decoction, pill, granule, capsule or tablet.Decoction in the dosage form of Chinese medicine composition of the present invention can on-the-spotly decoct, and also can decoct into oral liquid and take at any time, can also load in bottle and make spray, it is easy to carry, can take at any time, bring great convenience to patient.
The usage of Chinese medicine composition of the present invention: every day, sooner or later respectively once taking for 1 hour after meal, five days was a course for the treatment of.
Beneficial effect of the present invention: Chinese medicine composition compatibility of the present invention is scientific and reasonable, and drug effect complements each other, medicine source is wide, is cheaply easy to get; Relieved oedema or abdominal distension through diuresis or purgation by lung qi dispersing, warming spleen and stomach for dispelling cold, warming the kidney to invigorate YANG, invigorating the spleen and benefiting QI, dispersing the stagnated live-QI to relieve the stagnation of QI, reach effect of heat radiation lung heat clearing, relieving cough and asthma, blood stasis dispelling sending down the abnormal ascending QI, antiphlogistic antibacterial, eliminating pathogenic factor for supporting vital QI, through focus depths; Meanwhile, comprehensively can also nurse one's health thoroughly inside of human body function, enhance the immunity of human body, reach the object for the treatment of both the principal and secondary aspects of a disease; Treatment for allergic asthma has taking convenience, and instant effect, cure rate are high, stable curative effect, the feature not recurring and have no side effect.
Detailed description of the invention
Be clearly and completely described technical scheme of the present invention below in conjunction with specific embodiment, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
A kind of Chinese medicine composition for the treatment of allergic asthma, the raw material comprising following weight portion is made: Bal(n)phyllia sp. 10-15 part, old Caulis Perillae 6-12 part, Rhizoma Polygonati 10-15 part, Radix Dipsaci 10-15 part, Herba Ephedrae (processed) 6-12 part, Radix Scutellariae 10-15 part, Cortex Mori 6-12 part, Periostracum Cicadae 3-6 part, coltsfoot 10-15 part, Rhizoma Zingiberis 10-15 part, Radix Aconiti Lateralis Preparata 6-12 part, Flos Magnoliae 3-6 part, Fructus Xanthii 6-12 part, Fructus Viticis Negundo 10-15 part, Rhizoma Belamcandae 6-12 part, Herba Plantaginis 6-12 part, Radix Saposhnikoviae 6-12 part, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 20-40 part, Folium Elaeagni 10-15 part, Ramulus Cinnamomi 6-12 part, Cortex Eucommiae 6-12 part, PINGDIMU 10-15 part, Folium Mahoniae 6-12 part, Herba Artemisiae Scopariae 6-12 part, Flos Chrysanthemi Indici 6-12 part, Fructus Atriplicis Sibiricae 6-12 part.
Further, Chinese medicine composition of the present invention, the raw material comprising following weight portion is made: Bal(n)phyllia sp. 12 parts, old Caulis Perillae 9 parts, Rhizoma Polygonati 12 parts, Radix Dipsaci 12 parts, Herba Ephedrae (processed) 9 parts, Radix Scutellariae 12 parts, Cortex Mori 9 parts, Periostracum Cicadae 4.5 parts, coltsfoot 12 parts, Rhizoma Zingiberis 12 parts, Radix Aconiti Lateralis Preparata 9 parts, Flos Magnoliae 4.5 parts, Fructus Xanthii 9 parts, Fructus Viticis Negundo 12 parts, Rhizoma Belamcandae 9 parts, Herba Plantaginis 9 parts, Radix Saposhnikoviae 9 parts, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 30 parts, Folium Elaeagni 12 parts, Ramulus Cinnamomi 9 parts, the Cortex Eucommiae 9 parts, PINGDIMU 12 parts, Folium Mahoniae 9 parts, Herba Artemisiae Scopariae 9 parts, Flos Chrysanthemi Indici 9 parts, Fructus Atriplicis Sibiricae 9 parts.
Further, in Chinese medicine composition of the present invention, the dosage form of described Chinese medicine composition is the one in decoction, pill, granule, capsule or tablet.
embodiment one
Treat a Chinese medicine composition for allergic asthma, comprise following raw material: Bal(n)phyllia sp. 10g, old Caulis Perillae 6g, Rhizoma Polygonati 10g, Radix Dipsaci 10g, Herba Ephedrae (processed) 6g, Radix Scutellariae 10g, Cortex Mori 6g, Periostracum Cicadae 3g, coltsfoot 10g, Rhizoma Zingiberis 10g, Radix Aconiti Lateralis Preparata 6g, Flos Magnoliae 3g, Fructus Xanthii 6g, Fructus Viticis Negundo 10g, Rhizoma Belamcandae 6g, Herba Plantaginis 6g, Radix Saposhnikoviae 6g, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 20g, Folium Elaeagni 10g, Ramulus Cinnamomi 6g, Cortex Eucommiae 6g, PINGDIMU 10g, Folium Mahoniae 6g, Herba Artemisiae Scopariae 6g, Flos Chrysanthemi Indici 6g, Fructus Atriplicis Sibiricae 6g.
In above-mentioned raw materials, add 1500mL water, decoct, after boiling 3h, pour out decoction liquor; Remaining filtering residue is continued to decoct with water, decocts 3 times altogether; Decoction liquor is merged, concentrated, make decoction; This decoction is carried out sterilization fill through activated carbon filtration, a kind of Traditional Chinese medicinal spray for the treatment of allergic asthma; This Traditional Chinese medicinal spray, every bottled 25mL, 1h takes after meal, every day twice, each one, within five days, is a course for the treatment of.
embodiment two
Treat a Chinese medicine composition for allergic asthma, comprise following raw material: Bal(n)phyllia sp. 12g, old Caulis Perillae 9g, Rhizoma Polygonati 12g, Radix Dipsaci 12g, Herba Ephedrae (processed) 9g, Radix Scutellariae 12g, Cortex Mori 9g, Periostracum Cicadae 4.5g, coltsfoot 12g, Rhizoma Zingiberis 12g, Radix Aconiti Lateralis Preparata 9g, Flos Magnoliae 4.5g, Fructus Xanthii 9g, Fructus Viticis Negundo 12g, Rhizoma Belamcandae 9g, Herba Plantaginis 9g, Radix Saposhnikoviae 9g, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 30g, Folium Elaeagni 12g, Ramulus Cinnamomi 9g, Cortex Eucommiae 9g, PINGDIMU 12g, Folium Mahoniae 9g, Herba Artemisiae Scopariae 9g, Flos Chrysanthemi Indici 9g, Fructus Atriplicis Sibiricae 9g.
Above-mentioned raw materials is added water, soaks, distillation, concentrated, spraying dry, makes granule, often packs 1g, and wrap each serving with 1,1h takes after meal, every day 2 times, within five days, is a course for the treatment of.
embodiment three
Treat a Chinese medicine composition for allergic asthma, comprise following raw material: Bal(n)phyllia sp. 15g, old Caulis Perillae 12g, Rhizoma Polygonati 15g, Radix Dipsaci 15g, Herba Ephedrae (processed) 12g, Radix Scutellariae 15g, Cortex Mori 12g, Periostracum Cicadae 6g, coltsfoot 15g, Rhizoma Zingiberis 15g, Radix Aconiti Lateralis Preparata 12g, Flos Magnoliae 6g, Fructus Xanthii 12g, Fructus Viticis Negundo 15g, Rhizoma Belamcandae 12g, Herba Plantaginis 12g, Radix Saposhnikoviae 12g, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 40g, Folium Elaeagni 15g, Ramulus Cinnamomi 12g, Cortex Eucommiae 12g, PINGDIMU 15g, Folium Mahoniae 12g, Herba Artemisiae Scopariae 12g, Flos Chrysanthemi Indici 12g, Fructus Atriplicis Sibiricae 12g.
Above-mentioned raw materials is pulverized grinding, and mix homogeneously, makes pill, and every ball weight is 1g, and each serving using 2-4 ball, every day 2 times, 1h takes after meal, within five days, is a course for the treatment of.
embodiment four
Treat a Chinese medicine composition for allergic asthma, comprise following raw material: Bal(n)phyllia sp. 11g, old Caulis Perillae 7g, Rhizoma Polygonati 11g, Radix Dipsaci 14g, Herba Ephedrae (processed) 11g, Radix Scutellariae 14g, Cortex Mori 8g, Periostracum Cicadae 4g, coltsfoot 11g, Rhizoma Zingiberis 11g, Radix Aconiti Lateralis Preparata 8g, Flos Magnoliae 3.5g, Fructus Xanthii 7g, Fructus Viticis Negundo 11g, Rhizoma Belamcandae 11g, Herba Plantaginis 11g, Radix Saposhnikoviae 8g, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 25g, Folium Elaeagni 14g, Ramulus Cinnamomi 8g, Cortex Eucommiae 11g, PINGDIMU 11g, Folium Mahoniae 7g, Herba Artemisiae Scopariae 8g, Flos Chrysanthemi Indici 11g, Fructus Atriplicis Sibiricae 11g.
Soaked by above-mentioned raw materials, distillation, concentrated, dry, incapsulate, make capsule, every capsules dress 0.5g, each serving with 2,1h takes after meal, every day 2 times, within five days, is a course for the treatment of.
embodiment five
Treat a Chinese medicine composition for allergic asthma, comprise following raw material: Bal(n)phyllia sp. 13g, old Caulis Perillae 10g, Rhizoma Polygonati 13g, Radix Dipsaci 11g, Herba Ephedrae (processed) 8g, Radix Scutellariae 11g, Cortex Mori 11g, Periostracum Cicadae 5.5g, coltsfoot 13g, Rhizoma Zingiberis 13g, Radix Aconiti Lateralis Preparata 10g, Flos Magnoliae 5.5g, Fructus Xanthii 11g, Fructus Viticis Negundo 13g, Rhizoma Belamcandae 7g, Herba Plantaginis 8g, Radix Saposhnikoviae 11g, Lagenaria siceraria(Molina) Standl.var.depressa Ser. 35g, Folium Elaeagni 11g, Ramulus Cinnamomi 10g, Cortex Eucommiae 8g, PINGDIMU 14g, Folium Mahoniae 10g, Herba Artemisiae Scopariae 10g, Flos Chrysanthemi Indici 8g, Fructus Atriplicis Sibiricae 7g.
Soaked by above-mentioned raw materials, distillation, concentrated, dry, tabletting, makes tablet, the heavy 0.5g of every sheet, and each serving with 2,1h takes after meal, every day 2 times, within five days, is a course for the treatment of.
Set forth the present invention further below in conjunction with concrete test example, wherein, comprise the animal toxicity test of Chinese medicine composition of the present invention, pharmacodynamics test and clinical observation test.
animal toxicity test
By the Chinese medicine composition of the embodiment of the present invention one to embodiment five, carried out repeatedly animal toxicity test respectively, when testing at every turn, get rat 20, male and female dual-purpose, body weight 180-220g, be divided into two groups, often organize 10, wherein one group is overdose test group, another group is normal amount test group, and overdose test group consumption is 4.0g/kg, and normal amount test group consumption is 1.0g/kg, administering mode is administration by gavage administration, every day respectively once, takes one week sooner or later continuously, observes administration reaction every day; Test of many times all result shows, two groups of rat spirit, activity, diet, excretion are all normal; Cut open inspection, naked eyes examine main inside internal organs, no abnormality seen; Therefore, this Chinese medicine composition is without bad toxic and side effects.
animal pharmacodynamics test
Ovalbumin aerosol sucks the impact of drawing Cavia porcellus and breathing heavily
Get Cavia porcellus 70, body weight 200-250g, male and female half and half, be divided into 7 groups at random, be i.e. a matched group and 6 administration groups, wherein, administration group comprises the administration group of the embodiment of the present invention one to embodiment five, the Chinese medicine administration group of certain treatment allergic asthma commercially available; Only every Cavia porcellus is retreated outside intramuscular injection 4% ovalbumin normal saline 0.2mL/, meanwhile, lumbar injection 4% gel aluminum hydroxide 0.2mL sensitization.From sensitization second day, administration group carried out gastric infusion with Chinese medicine composition of the present invention and certain commercially available Chinese medicine respectively, and matched group equivalent distilled water gavages, and amounted to two weeks.After last administration, animal is put in the bell glass of sealing, after peace and quiet, starts air compressor, after spraying into 3.5% ovalbumin normal saline 30s with the constant voltage of 53KPa, observe Cavia porcellus in 6min and occur incubation period and the tic number of animals of asthmatic tic; Experimental result gathers as shown in table 1.
Table 1 different pharmaceutical draws on ovalbumin aerosol the impact that Cavia porcellus breathes heavily
Remarks: compared with matched group, *---P<0.05; *---P<0.01.
As can be seen from Table 1, five kinds of Chinese medicine compositions of the present invention all can extend ovalbumin normal saline solution significantly and draw the incubation period of breathing heavily Cavia porcellus; Compared with treating the Chinese medicine of allergic asthma with commercially available certain, five kinds of Chinese medicine compositions of the present invention have obvious advantage, and namely its asthmatic latent period obviously extends, and tic size of animal obviously reduces; Therefore, five kinds of Chinese medicine compositions of the present invention have advantage of significantly relievining asthma.
clinical observation is tested
Patient data
Random selecting 5-60 year isolated from allergic asthmatic patients 600 example, wherein, man 300 example, female 300 example, mean age is 35.6 years old, the course of disease 1 year to 15 years, average course of disease 5.6 years, is divided into six groups according to the method for M-F, ratio of age and course of disease balanced proportion, be respectively a matched group and five treatment groups, often organize each 100 examples, do not have diversity statistically between six groups of patients, six groups of patients all meet allergic asthma diagnostic criteria; These six groups of patients are before accepting this treatment, and all once with the Therapeutic Method such as Western medicine or Chinese medicine, but effect is not remarkable, easily recurs, can not dig up the roots.
Therapeutic scheme
Matched group: patient takes the Chinese medicine of certain commercially available treatment allergic asthma orally, it is decoction, one after each meal, three times on the one, and each 50mL two weeks is a course for the treatment of, takes three courses for the treatment of continuously;
Treatment group: patient takes five kinds of Chinese medicine compositions of the embodiment of the present invention one to embodiment five respectively orally, and 1h takes after meal, a twice-daily, five days is a course for the treatment of, takes two courses for the treatment of continuously.
Follow up a case by regular visits to every day once, evaluate respectively before taking medicine He after taking medicine, treat complete after, continue to follow up a case by regular visits to 3 years, before treatment, further consultation and fill in case report form when following up a case by regular visits to.
All experimenters all must not merge the medicine using other treatment allergic asthma any and the medicine that may affect clinical efficacy and untoward reaction evaluation at duration of test.
The standard of curative effect evaluation
Recovery from illness: more than the symptomatic treatment medicine half a year of stopping using, without clinical symptoms and sign;
Effective: transference cure, chest films showed two lung shows no obvious abnormalities;
Take a turn for the better: symptom alleviates, disease amelioration, and chest films showed two pneumonopathy stove makes moderate progress;
Invalid: symptom is without improvement, and rabat shows that two parts of focuses are with originally similar or increase the weight of.
Therapeutic effect
Table 2 clinical treatment outcome summary sheet
Clinical observation result
Six groups of clinical treatment outcome gather as shown in table 2, and as can be seen from Table 2, five kinds of Chinese medicine compositions of the present invention all have good curative effect to treatment allergic asthma, and clearly, cure rate obviously raises advantage, and cure rate reaches 85%, and total effective rate is 99%; Dose is few, taking convenience, mild in medicine property and, significantly reduce the misery of patient; Instant effect, stable curative effect, short treating period, has no side effect, treating both the principal and secondary aspects of a disease.
Model case
Case 1: field, female, 23 years old, suffers from allergic asthma 5 years, every winter cold aggravation in season, cough and asthma, spit more than, informal dress antiinflammatory anti-asthmatic, does not effect a radical cure always; Take Chinese medicine composition of the present invention, sooner or later respectively once, one after each meal; After taking a course for the treatment of, cough and asthma symptom obviously disappear, and chest films showed two lung shows no obvious abnormalities; Continue to take a course for the treatment of to strengthen consolidating, follow up a case by regular visits to 2 years, have no recurrence, health is good.
Case 2: gold certain, man, 60 years old, suffer from allergic asthma 15 years, private prosecution is often slept to midnight and is breathed heavily for no reason at all, sometimes in good shape, and a burst of cold wind is blown over or just breathed heavily after contacting some penetrating odor and do not come suddenly; Or daytime, state was as ordinary person, night suppresses suddenly awake from sleep, and that breathes heavily feels bad very much, even has the sensation of suffocating; Took the Chinese medicine of some treatment allergic asthmas in the past, poor effect, has during drug withdrawal repeatedly; Take Chinese medicine composition of the present invention, sooner or later respectively once, one after each meal; After taking a course for the treatment of, cough and asthma symptom obviously disappear, and chest films showed two lung shows no obvious abnormalities; Continue to take a course for the treatment of, to strengthen consolidating; Follow up a case by regular visits to 3 years, have no recurrence, health is good.
Case 3: Chen, man, 5 years old, suffer from allergic asthma 1 year, expectoration during morbidity, feel suffocated, cough with asthma, taken a lot of Western medicine, but the state of an illness again and again always, suppresses the severity of breathing heavily when showing effect serious especially; Take Chinese medicine composition of the present invention, sooner or later respectively once, one after each meal; After taking a course for the treatment of, cough and asthma symptom disappear substantially, and chest films showed two lung shows no obvious abnormalities; Continue to take a course for the treatment of to strengthen consolidating, follow up a case by regular visits to 1 year, then without rebound phenomenon.
Therefore, the beneficial effect of Chinese medicine composition of the present invention is: Chinese medicine composition compatibility of the present invention is scientific and reasonable, and drug effect complements each other, and medicine source is wide, is cheaply easy to get; Relieved oedema or abdominal distension through diuresis or purgation by lung qi dispersing, warming spleen and stomach for dispelling cold, warming the kidney to invigorate YANG, invigorating the spleen and benefiting QI, dispersing the stagnated live-QI to relieve the stagnation of QI, reach effect of heat radiation lung heat clearing, relieving cough and asthma, blood stasis dispelling sending down the abnormal ascending QI, antiphlogistic antibacterial, eliminating pathogenic factor for supporting vital QI, through focus depths; Meanwhile, comprehensively can also nurse one's health thoroughly inside of human body function, enhance the immunity of human body, reach the object for the treatment of both the principal and secondary aspects of a disease; Treatment for allergic asthma has taking convenience, and instant effect, cure rate are high, stable curative effect, does not recur, and has no side effect.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.