CN108096396A - A kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa - Google Patents
A kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa Download PDFInfo
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The present invention provides a kind of Traditional Chinese medicine gel compositions antibacterial for vaginal mucosa, are made of the raw material of following weight ratio：The root of Dahurain angelica, Cananga odorata quintessence oil, Geranium Essential, propolis, frutus cnidii, kuh-seng, frankincense, honeysuckle, safflower, Radix Angelicae Sinensis, grape pip, carbomer, remaining be purified water；The product of the present invention enters after vagina, affected part can be diffused to rapidly, the living environment of harmful bacteria is destroyed, adjusts the colony balance and acid-base balance of intravaginal, repairs damaged vaginal mucosa, then go deep into vagina and progressively clear up the toxin and harmful bacteria being attached to inside vagina, the autoimmunity of vagina is made gradually to be restored, for safeguarding the normal weakly acidic condition of vagina, recovers vagina self-cleaning antibacterial ability, it nourishes lubricious, there is fabulous maintenance effect.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa.
Background technology
The vagina mucosa of female reproductive system refers to the holding vaginal walls surface wettability of vaginal walls secretion, keeps table
The mucus film layer of face vigor, due to various reasons, vagina can be by pathogenic infection or the colony balance and soda acid because of vagina by women
Equilibrium problem causes vaginal environment to change, and causes colporrhagia or various gynaecological diseases, in terms of traditional Chinese medical science angle, bacterial vaginosis BV
Etiology and pathogenesis mostly because liver,spleen,kidney three is dirty and wind, cold, wet, hot heresy；The etiology and pathogenesis of trichomonas vaginitis is mainly because wet
Heat is pented up, caused by worm-eaten the moon；Monilial vaginitis etiology and pathogenesis mostly because it is wet it is turbid pent up, infect cult poison caused by；Senile the moon
The etiology and pathogenesis main mechanism of road inflammation be the deficiency of liver-yin and kidney-yin, damp invasion of lower energizer, and mainly think in doctor trained in Western medicine by virus or germ infection institute
It causes, vaginitis causes to perplex to women's daily life, may result in infertile, serious influence life and health.
The content of the invention
According to above-mentioned elaboration, it is an object of the invention to provide a kind of Chinese medicine composition gel, for inhibiting vaginal mucosa
Infection, have it is promoting blood circulation and removing blood stasis, the effect of antibacterial anti-inflammatory.
Technical solution provided by the invention：A kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa, is by following heavy
The raw material of amount ratio is made：
The root of Dahurain angelica 1%~3%, Cananga odorata quintessence oil 3%~8%, Geranium Essential 1%~4%, propolis 1%~3%, frutus cnidii
8%~15%, kuh-seng 1%~3%, frankincense 1%~3%, honeysuckle 1%~3%, safflower 4%~6%, Radix Angelicae Sinensis 1%~
6%th, grape pip 1%~2%, carbomer 1%~3%, remaining be purified water；
In above-mentioned technical proposal, the root of Dahurain angelica 1%, Cananga odorata quintessence oil 1%, Geranium Essential 1%, propolis 1%, frutus cnidii 1%, hardship
Ginseng 1%, frankincense 1%, honeysuckle 1%, safflower 1%, Radix Angelicae Sinensis 1%, grape pip 1%, carbomer 1%, remaining be purified water.
A kind of preparation method for the antibacterial Traditional Chinese medicine gel composition of vaginal mucosa provided by the invention is：It will be described heavy
Measure part raw material：Cananga odorata quintessence oil, Geranium Essential, propolis, with the roots of Dahurain angelica of parts by weight, kuh-seng, frankincense, honeysuckle, safflower, when
Return, frutus cnidii, grape seed extract, mixed with carbomer, add in purified water and mix gel.
The extraction of Chinese medicine uses aqueous solvent extracting mode, the active ingredient of extraction.
For the present invention based on the pathogenesis to gynecological disease and treatment principle, compatibility is reasonable, science, is tested through a large amount of clinics
Card, without any toxicity and side effects, product of the invention enters after vagina, can diffuse to affected part rapidly, destroys the existence ring of harmful bacteria
Border adjusts the colony balance and acid-base balance of intravaginal, repairs damaged vaginal mucosa, then gos deep into vagina and progressively clear up attachment
Toxin and harmful bacteria inside vagina, make the autoimmunity of vagina gradually be restored, for safeguarding that vagina is normal
Weakly acidic condition recovers vagina self-cleaning antibacterial ability, and nourishing is lubricious, there is fabulous maintenance effect.
Specific embodiment
Technical scheme is clearly and completely described below, it is clear that described embodiment is only this
Invention part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art exist
All other embodiments obtained under the premise of creative work are not made, belong to the scope of protection of the invention.
The compatibility of drugs of the present invention is reasonable, and component effect is：
The effect of root of Dahurain angelica, warm-natured, acrid flavour, hardship attach to the lung and stomach meridians, and the present invention is using root of Dahurain angelica antipyretic-antalgic, anti-inflammatory, antibacterial.
Cananga odorata quintessence oil, using there is good anti-inflammatory effects on the skin, the present invention is using Cananga odorata quintessence oil is anti-inflammatory, work(of antibacterial
Effect.
The effect of Geranium Essential, the present invention utilizes anti-inflammatory Geranium Essential, antibacterial.
Propolis has the effect of moisturizing myogenic, anti-inflammatory analgetic.
Frutus cnidii, warm-natured, bitter return kidney channel, and the present invention utilizes antibacterial, antimycotic, anti-inflammatory effect.
Kuh-seng, bitter is cold in nature, the thoughts of returning home, liver, stomach, large intestine, bladder warp, has heat-clearing, eliminating dampness, and the effect of desinsection can control drop
Worm property vaginitis.
Frankincense, acrid flavour, hardship are warm-natured.The thoughts of returning home, liver, the spleen channel, the present invention utilize frankincense promoting blood circulation analgesic therapy, the function of detumescence and promoting granulation.
The effect of safflower, function of promoting blood circulation to disperse blood clots is strong, and the present invention utilizes safflower promoting blood circulation and removing blood stasis, swelling and pain relieving.
Kuh-seng, bitter is cold in nature, has antibacterial, anti-inflammatory effect.
Frutus cnidii, acrid flavour, hardship are warm-natured；It is slightly poisonous.There are antimycotic, antifungi, removing toxic substances desinsection, eliminating dampness, the function of wind-dispelling.
Kuh-seng, acrid flavour is cold in nature, there is heat-clearing and fire-dispersing, detumescence effect.
Frankincense as excitants, acts on skin or mucous membrane, there is refrigerant itching-relieving action.
Honeysuckle, cold in nature, sweet in flavor, channel tropism lung, stomach, the present invention using honeysuckle resisting pathogenic microbes, it is anti-inflammatory, antipyretic,
Anti-allergic effects.
Safflower, it is sweet in flavor mild-natured, for promoting blood circulation and removing blood stasis in the present invention.
Radix Angelicae Sinensis, it is sweet in flavor, pungent, bitter, it is warm-natured, enter liver, the heart, the spleen channel, it can be with blood-nourishing and blood, tonifying blood and regulating menstruation, promoting blood circulation and stopping pain.
Grape pip can go deep into cell, fundamentally inhibit the release of sensitizing factor " histamine ", improve cell to anaphylactogen
Tolerance；Remove sensitization free radical, anti-inflammatory, antiallergy；Stablize skin heart tissue, effectively adjust immunity of organisms.
Carbomer is the effect of thickening.
According to above-mentioned component and compatibility principle analysis, the present invention discloses following embodiment.
Embodiment：
It takes：A kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa, is to be made from the following raw materials in parts by weight：
Root of Dahurain angelica effective content is effective for 10% Angelica Dahurica extract 10g, Cananga odorata quintessence oil 10g, Geranium Essential 10g, propolis
Common cnidium fruit P.E 10g that propolis 10g that content is 10%, frutus cnidii effective content are 10%, matrine effective content are
Frankincense seed extract 10g that 98% shrubby sophora extract 10g, frankincense effective content are 10%, honeysuckle effective content are 10%
Honegsukle flower P.E 10g, safflower effective content be 10% safranine flower extract 10g, Radix Angelicae Sinensis effective content be 10%
Angelica extract 10g, the grape seed extract 10g that grape pip effective content is 10%, carbomer 10g plus purified water are extremely
1000g, stirs evenly gelled, and the last weight of mixture is 1000g.
In use, Chinese medicine composition gel is injected intravaginal by patient.
To show the fungistatic effect of the present invention, the embodiment of the present invention does bacteriostatic test：
First, equipment
1st, test strain：Escherichia coli (8099), 9 generations of culture, Candida albicans (ATCC10231), culture 9 generations, golden yellow
Color staphylococcus (ATCC6538) cultivated for 9 generations, is provided by Chinese Culture Collection Center.
2nd, general English agar medium, sabouraud's agar are provided by Beijing road and bridge technology Co., Ltd.
3/0.03mol/L phosphate buffer solution (PBS)
4th, carrier：Filter paper (2.0cm × 3.0cm), sterile measuring pipette, sterilized petri dishes, sterile test tube, constant incubator
Deng
2nd, sample is the present embodiment 5g, is put into sterile mortar grinding, crushes, mixing, is put into sterilized petri dishes and is directly pressed down
Bacterium is tested.
3rd, method is according to GB15979-200《Disposable Sanitary Accessory sanitary standard》Appendix C 4,《Disinfection technology is advised
Model》2002 editions 2.1.8 test.
Bacteriostatic test is carrier test, and 20 DEG C ± 1 DEG C of test temperature, experiment is repeated 3 times.
4th, result
Under conditions of 20 DEG C ± 2 DEG C of test temperature, embodiment is to Escherichia coli, Candida albicans, Staphylococcus aureus
Bacterium inhibition.
The embodiment of the present invention is shown in Table 1 to the inhibition inspection of staphylococcus aureus；
The inhibition of 1 staphylococcus aureus of table
The embodiment of the present invention is shown in Table 2 for the inhibition inspection of Candida albicans.
The inhibition of 2 Candida albicans of table
The embodiment of the present invention is shown in Table 3 to the inhibition inspection of Escherichia coli；
The inhibition of 3 Escherichia coli of table
The conclusion tested above, for embodiment to Escherichia coli, Candida albicans, staphylococcus aureus inhibiting rate are reachable
More than 90%.
Meanwhile to do bright Tests For Irritating Effects as follows for this hair embodiment：
First, material and method
Experimental animal provides Japan big ear various schools of thinkers rabbit 6 by Xi'an Jiaotong University Medical College's Experimental Animal Center, female, body
Weigh 2.0-2.5kg, primary animal, credit number：SCXK (Shan) 2014-003, feed bedding and padding source Xi'an Communications University doctor
Institute's Experimental Animal Center provides.
Animal room environmental：22-25 DEG C of temperature, relative humidity：45% -55%.
2nd, Tests For Irritating Effects method
1st, test basis《Disinfection technology standard》2002 editions 2.1.8 test.
2nd, tested material dosage：2g/ is only.
3rd, test method：6 big ear various schools of thinkers rabbits of estrus Japan are randomly divided into 2 groups, respectively tested material and control group,
Every group 3, supine is fixed during experiment, and tested material group Via vagina injection tested material, control group gives physiological saline, and animal faces upward
Sleeping fixed 4h, makes tested material be come into full contact with vaginal mucosa.After the test, animal puts back to raising in cage, puts to death animal afterwards for 24 hours
Phenomena such as taking out vagina tissue, visually examining mucous membrane denaturation, secretion, the congestion of blood vessel, oedema, such as changes and does pathologic group
It knits to check.
3rd, result of the test, tested material group vaginal mucosa form is normal, no secretion, without congested, swelling, has no that mucous membrane becomes
Property.
4th, conclusion：Embodiment is 0 for rabbit vagina mucosa irritation reaction average score, according to《Disinfection technology standard》
Medial vagina mucosa irritation reacts pulvis standard, belongs to non-stimulated.
To show the clinical application effect of the present invention, the present invention is proved through clinical and experimental study：To the composition of embodiment
Crowd through age groups and different gynaecological diseases carries out test effect, and through experiment, this product is for bacterial vaginitis, trichomonad
Property the vaginal diseases such as vaginitis, monilial vaginitis, purulent vaginitis, colpitis simplex there is good effect, such as
Patient there are leucorrhea increasing or has foul smell, vulva to have itch, scorching hot before use, and the symptoms such as vaginal relaxation, intercourse pain make
With obtaining larger improvement after 3-7 days, after when use cleans vulva, 5 grams of this product is taken, gel is slowly injected uncomfortable to vagina
Position.It is 1-2 times, every time 5 grams daily.
The above description is merely a specific embodiment, but protection scope of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can readily occur in change or replacement, should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention described should be subject to the protection scope in claims.
Claims (2)
1. a kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa, it is characterised in that：It is by the raw material system of following weight ratio
Into：The root of Dahurain angelica 1%~3%, Cananga odorata quintessence oil 3%~8%, Geranium Essential 1%~4%, propolis 1%~3%, frutus cnidii 8%~
15%th, kuh-seng 1%~3%, frankincense 1%~3%, honeysuckle 1%~3%, safflower 4%~6%, Radix Angelicae Sinensis 1%~6%, Portugal
Grape seed 1%~2%, carbomer 1%~3%, remaining be purified water；
By the raw material：Cananga odorata quintessence oil, Geranium Essential, propolis, the root of Dahurain angelica, kuh-seng, frankincense, gold and silver with parts by weight
Flower, safflower, Radix Angelicae Sinensis, frutus cnidii, grape seed extract, mix with carbomer, add in purified water and mix gel.
2. a kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa according to claim 1, it is characterised in that：Be by
The raw material of following weight ratio is made：The root of Dahurain angelica 1%, Cananga odorata quintessence oil 1%, Geranium Essential 1%, propolis 1%, frutus cnidii 1%, kuh-seng
1%th, frankincense 1%, honeysuckle 1%, safflower 1%, Radix Angelicae Sinensis 1%, grape pip 1%, carbomer 1%, remaining be purified water.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810188608.XA CN108096396A (en) | 2018-03-07 | 2018-03-07 | A kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810188608.XA CN108096396A (en) | 2018-03-07 | 2018-03-07 | A kind of Traditional Chinese medicine gel composition antibacterial for vaginal mucosa |
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| Publication Number | Publication Date |
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| CN108096396A true CN108096396A (en) | 2018-06-01 |
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ID=62206001
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108686124A (en) * | 2018-07-23 | 2018-10-23 | 广州蜜蜜健康科技有限公司 | A kind of antibacterial formula of female private part nursing |
| CN108721449A (en) * | 2018-07-30 | 2018-11-02 | 西安万和医药科技有限公司 | One kind effectively enhancing the gel of anti-HPV infection for inhibiting HPV infection |
| CN110585418A (en) * | 2018-06-13 | 2019-12-20 | 广州合伊美生物科技有限公司 | External use disinfection essential oil emulsion for women and production process thereof |
| CN110652578A (en) * | 2018-06-29 | 2020-01-07 | 重庆合钰成贸易有限公司 | Female soft care gel and preparation method thereof |
| CN112237625A (en) * | 2019-07-17 | 2021-01-19 | 创技公司株式会社 | Composition for feminine cleanser comprising natural extract |
| CN112316012A (en) * | 2020-11-19 | 2021-02-05 | 陕西康乐实业有限公司 | Moisturizing antibacterial gel and preparation method thereof |
| CN112370490A (en) * | 2020-11-21 | 2021-02-19 | 陕西远志医药生物工程有限公司 | Polysaccharide antibacterial gel and preparation method thereof |
| CN112494617A (en) * | 2020-09-30 | 2021-03-16 | 金方卓越(厦门)生物科技有限公司 | Gynecological bacteriostatic natural herbal medicine formula and preparation method |
| CN113134066A (en) * | 2021-05-07 | 2021-07-20 | 诸暨市博美生物科技有限公司 | Preparation method of gynecological gel |
-
2018
- 2018-03-07 CN CN201810188608.XA patent/CN108096396A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110585418A (en) * | 2018-06-13 | 2019-12-20 | 广州合伊美生物科技有限公司 | External use disinfection essential oil emulsion for women and production process thereof |
| CN110652578A (en) * | 2018-06-29 | 2020-01-07 | 重庆合钰成贸易有限公司 | Female soft care gel and preparation method thereof |
| CN108686124A (en) * | 2018-07-23 | 2018-10-23 | 广州蜜蜜健康科技有限公司 | A kind of antibacterial formula of female private part nursing |
| CN108721449A (en) * | 2018-07-30 | 2018-11-02 | 西安万和医药科技有限公司 | One kind effectively enhancing the gel of anti-HPV infection for inhibiting HPV infection |
| CN112237625A (en) * | 2019-07-17 | 2021-01-19 | 创技公司株式会社 | Composition for feminine cleanser comprising natural extract |
| CN112494617A (en) * | 2020-09-30 | 2021-03-16 | 金方卓越(厦门)生物科技有限公司 | Gynecological bacteriostatic natural herbal medicine formula and preparation method |
| CN112494617B (en) * | 2020-09-30 | 2023-01-13 | 金方卓越(厦门)生物科技有限公司 | Gynecological bacteriostatic natural herbal medicine formula and preparation method |
| CN112316012A (en) * | 2020-11-19 | 2021-02-05 | 陕西康乐实业有限公司 | Moisturizing antibacterial gel and preparation method thereof |
| CN112370490A (en) * | 2020-11-21 | 2021-02-19 | 陕西远志医药生物工程有限公司 | Polysaccharide antibacterial gel and preparation method thereof |
| CN113134066A (en) * | 2021-05-07 | 2021-07-20 | 诸暨市博美生物科技有限公司 | Preparation method of gynecological gel |
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Application publication date: 20180601 |