CN111329807A

CN111329807A - Acne removing cream and preparation method thereof

Info

Publication number: CN111329807A
Application number: CN202010255826.8A
Authority: CN
Inventors: 莫远清; 廖声友
Original assignee: Guangzhou Yixuan Fine Chemical Co ltd
Current assignee: Guangzhou Yixuan Fine Chemical Co ltd
Priority date: 2020-04-02
Filing date: 2020-04-02
Publication date: 2020-06-26

Abstract

The invention relates to acne-removing cream and a preparation method thereof. The acne-removing cream mainly comprises: hamamelis virginiana liquid, zanthoxylum bungeanum fruit extract, capsicum frutescens fruit extract, kava root extract, sophora flavescens root extract, loquat leaf extract, phellodendron amurense bark extract, artemisia capillaris plant liquid, mulberry root bark extract, glycyrrhiza glabra root extract, camphor tree rhizome extract and the like. The acne-removing cream takes various natural plant extracts as a skin conditioner, so that the irritation to the skin is reduced, and the acne-removing cream has strong acne-removing and antibacterial effects; the preparation method is simple to operate, the process is easy to control, and large-scale production is facilitated.

Description

Acne removing cream and preparation method thereof

Technical Field

The invention belongs to the field of skin care products, and particularly relates to acne removing cream and a preparation method thereof.

Background

The acne-removing cream is a cosmetic with the functions of eliminating and relieving whelk. The acne is commonly known as acne, and is also called as whelk, pimple or comedo. The reason is that: the skin is often inflamed due to the blockage of hair follicles and sebaceous glands, accompanied by the growth of bacteria. The acne cream can effectively clean, beautify and relieve acne skin.

However, the existing acne removing cream usually uses a chemical synthetic product as a main force for the acne removing effect, and the acne removing cream has large stimulation to skin and is easy to cause the recurrence of the affected part.

Disclosure of Invention

In order to solve the problems in the prior art, the invention provides an acne-removing cream and a preparation method thereof. The acne-removing cream takes various natural plant extracts as a skin conditioner, so that the irritation to the skin is reduced, and the acne-removing cream has strong acne-removing and antibacterial effects; the preparation method is simple to operate, the process is easy to control, and large-scale production is facilitated.

The scheme of the invention is that the acne-removing cream comprises a component A, a component B, a component C and a component D; the component A comprises the following raw materials in parts by weight: 4.5-5.5 parts of cyclopentadimethylsiloxane, 3.5-4.5 parts of ethylhexyl palmitate, 3.5-3.7 parts of cetearyl alcohol, 2.3-2.5 parts of cetearyl glucoside, 1-2 parts of laurocapram, 0.6-1.0 part of polydimethylsiloxane and 0.3-0.5 part of menthol; the component B comprises the following raw materials in parts by weight: 3.5-4.5 parts of propylene glycol, 0.3-0.7 part of p-hydroxyacetophenone, 0.08-0.12 part of carbomer, 0.04-0.06 part of xanthan gum, 0.1-0.3 part of allantoin, 0.04-0.06 part of EDTA disodium and 55-65 parts of water; the component C comprises the following raw materials in parts by weight: 0.2-0.3 part of polyacrylamide, 0.1-0.2 part of C13-14 isoparaffin, 0.32-0.04 part of laureth-70.03, 0.15-0.2 part of water and 0.01-0.03 part of arginine; the component D comprises the following raw materials in parts by weight: 6-10 parts of witch hazel liquid, 0.1-0.15 part of zanthoxylum bungeanum fruit extract, 0.13-0.15 part of capsicum frutescens fruit extract, 0.1-0.11 part of kava root extract, 0.12-0.14 part of sophora flavescens root extract, 0.01-0.03 part of p-hydroxyacetophenone, 0.01-0.03 part of 1, 2-hexanediol, 0.3-0.35 part of butanediol, 3-3.3 parts of water, 0.8-0.9 part of loquat leaf extract, 0.5-0.7 part of phellodendron bark extract, 0.3-0.34 part of artemisia capillaris plant liquid, 0.25-0.3 part of mulberry root extract, 0.14-0.18 part of glycyrrhiza glabra root extract, 0.03-0.05 part of butanediol, 0.03-0.05 part of glycerin, 1.5-2.5 parts of hexanediol, 0.4 part of camphor tree extract, 0.6-0.6 part of glycyrrhiza glabra root extract, 0.6-0.09 part of hexanediol root extract, 0.06 part of essence, 0.09-0.06 part of hexanediol essence, and 0.09-0.06 part of.

Preferably, the acne cream comprises component a, component B, component C and component D; the component A comprises the following raw materials in parts by weight: 5 parts of cyclopenta dimethyl silicone polymer, 4 parts of ethylhexyl palmitate, 3.6 parts of cetearyl alcohol, 2.4 parts of cetearyl glucoside, 1.5 parts of laurocapram, 0.8 part of polydimethylsiloxane and 0.4 part of menthol; the component B comprises the following raw materials in parts by weight: 4 parts of propylene glycol, 0.5 part of p-hydroxyacetophenone, 0.1 part of carbomer, 0.05 part of xanthan gum, 0.2 part of allantoin, 0.05 part of EDTA disodium and 60 parts of water; the component C comprises the following raw materials in parts by weight: 0.25 part of polyacrylamide, 0.15 part of C13-14 isoparaffin, 0.18 part of laureth-70.035 part of water and 0.02 part of arginine; the component D comprises the following raw materials in parts by weight: 8 parts of witch hazel liquid, 0.12 part of zanthoxylum bungeanum fruit extract, 0.14 part of capsicum frutescens fruit extract, 0.105 part of kava root extract, 0.13 part of sophora flavescens root extract, 0.02 part of p-hydroxyacetophenone, 0.02 part of 1, 2-hexanediol, 0.32 part of butanediol, 3.15 parts of water, 0.85 part of loquat leaf extract, 0.6 part of phellodendron bark extract, 0.32 part of artemisia capillaris thunbergii plant liquid, 0.27 part of mulberry root bark extract, 0.16 part of glycyrrhiza glabra root extract, 0.04 part of butanediol, 0.04 part of glycerol, 2 parts of hexanediol, 0.5 part of camphor tree rhizome extract, 0.5 part of 1, 2-hexanediol, 0.78 part of quaternary ammonium salt-730.05 and 0.08 part of essence.

Preferably, the preparation method of the loquat leaf extract comprises the following steps:

(1) drying and crushing loquat leaves to obtain loquat leaf powder;

(2) mixing the loquat leaf powder obtained in the step (1) with distilled water, heating and refluxing for extraction, and filtering primary filter residue and primary extracting solution after the extraction is finished;

(3) mixing the primary filter residue obtained in the step (2) with ethanol, heating and refluxing for extraction, and filtering to obtain secondary filter residue and a secondary extracting solution;

(4) and mixing the primary extract and the secondary extract to obtain a mixed solution, concentrating and drying to obtain the loquat-leaf-free extract.

Preferably, in the step (1), the crushing is carried out until the granularity is 50-70 meshes.

Preferably, in the step (2), the weight ratio of the loquat leaf powder to the distilled water is 1: 1-2; the heating reflux temperature is 90-94 ℃, and the extraction time is 1-2 h.

Preferably, in the step (3), the weight ratio of the primary filter residue to the ethanol is 1: 2-4; the heating reflux temperature is 68-72 ℃, and the extraction time is 4-6 h.

Preferably, in the step (4), the concentration is carried out until the concentration is 1/4-1/3 of the original volume; the drying temperature is 40-50 ℃.

Based on the same technical concept, the invention further provides a preparation method of the acne-removing cream, which comprises the following steps:

(i) heating and stirring all the raw materials in the component A, fully mixing, and keeping the temperature for later use to obtain a mixture A;

(ii) heating and stirring all the raw materials in the component B, fully mixing, and keeping the temperature for later use to obtain a mixture B;

(iii) emulsifying the mixture B under a vacuum condition, adding the mixture A, uniformly stirring, adding all the raw materials of the component C, homogenizing, adding all the raw materials of the component D after the temperature is reduced, fully stirring, discharging and standing to obtain the acne-removing cream.

Preferably, in the steps (i) and (ii), the heating and stirring temperature is 75-80 ℃.

Preferably, in step (iii), the homogenization time is 3-5 min.

In order to facilitate the understanding of the present invention, some of the raw materials of the present invention are further described below.

And (3) Chinese prickly ash fruit extract: has strong antibacterial and bactericidal effects, and can protect skin from being damaged.

Capsicum frutescens extract: the product is rich in high unit vitamin C, carotene, protein and minerals, is a strong antioxidant, can brighten skin color around eyes, can improve skin irritation resistance, and has good moisture keeping effect.

Kava root extract: has excellent antioxidant, antibacterial, antiinflammatory and dispersing effects. And can remove the internal wastes of the skin and help to remove the aging substances which are easy to induce various skin problems.

Extract of kuh-seng root: the effective component is mainly matrine, which is a traditional herbal medicine. It can be used for treating eczema and dermatitis, and has antibacterial and anti-inflammatory effects; has effects in promoting collagen production, promoting fibroblast proliferation, and resisting skin aging; meanwhile, the product has the efficacy of moisturizing.

Loquat leaf extract: has broad-spectrum antibacterial effect, and can inhibit Staphylococcus aureus, Staphylococcus albus, hemolytic streptococcus, pneumococcus, and Catalpa.

Phellodendron amurense bark extract: is a yellow powder extract product of bark of phellodendron amurense belonging to Rutaceae. Mainly contains berberine, and contains palmatine, phellodendrine, dauricine, sinomenine, phellodendron bark, etc. Can promote the generation of collagen, and has the function of anti-aging by combining the oxidation resistance; can inhibit hair growth, and can be used for treating skin hirsutism in combination with aromatase activation; has anti-inflammatory and odor inhibiting effects.

Mulberry root bark extract: contains reducing sugar, pentosan, galactoside, tannin, flavone, etc. Can inhibit elastase, and has antiaging effect; promoting the synthesis of fiber bud cell brain amide and softening and moistening skin; can well prevent and treat acne caused by high androgen; has contraction effect on collagen fiber, and can be used for reducing weight; promoting the activation of luciferase, and showing that the luciferase has anti-inflammatory efficacy; can inhibit tyrosinase activity, and has skin whitening effect.

Glycyrrhiza glabra root extract: can penetrate into skin and maintain high activity, effectively inhibit activity of multiple enzymes (such as tyrosinase) in melanin production process, and simultaneously the Glycyrrhiza glabra extract also has effects of preventing pachylosis, anti-inflammatory and antibacterial.

The invention has the beneficial effects that:

1. according to the acne-removing cream disclosed by the invention, various natural plant extracts are used as a skin conditioner, so that the irritation to the skin is reduced, and meanwhile, the acne-removing cream has strong acne-removing and bacteriostatic effects; and the detection is carried out according to national standards, and all the sensory, physicochemical and sanitary items of the product meet the national standards.

2. The preparation method of the acne-removing cream disclosed by the invention is simple to operate, and the process is easy to control, and is beneficial to large-scale production.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.

Example 1

The embodiment provides a preparation method of an acne-removing cream, which comprises the following steps:

(I) the preparation method of the loquat leaf extract comprises the following steps:

(1) drying loquat leaves, and crushing the loquat leaves until the granularity is 50 meshes to obtain loquat leaf powder;

(2) mixing the loquat leaf powder obtained in the step (1) with distilled water according to the weight ratio of 1:1, heating and refluxing for extraction for 1h at the temperature of 90 ℃, and filtering primary filter residue and primary extracting solution after the extraction is finished;

(3) mixing the primary filter residue obtained in the step (2) with ethanol according to the weight ratio of 1:2, heating and refluxing for extraction for 4 hours at 68 ℃, and filtering secondary filter residue and secondary extracting solution after the extraction is finished;

(4) mixing the primary extractive solution and the secondary extractive solution to obtain a mixed solution, concentrating to 1/4 of the original volume, and drying at 40 deg.C to obtain folium Eriobotryae extract.

(II) preparing the acne-removing cream, which comprises the following steps:

(i) stirring 4.5kg of cyclopentadimethylsiloxane, 3.5kg of ethylhexyl palmitate, 3.5kg of cetearyl alcohol, 2.3kg of cetearyl glucoside, 1kg of laurocapram, 0.6kg of polydimethylsiloxane and 0.3kg of menthol at 75 ℃, fully mixing and keeping the temperature for later use to obtain a mixture A;

(ii) stirring 3.5kg of propylene glycol, 0.3kg of p-hydroxyacetophenone, 0.08kg of carbomer, 0.04kg of xanthan gum, 0.1kg of allantoin, 0.04kg of disodium EDTA and 55kg of water at 75 ℃, fully mixing, and keeping the temperature for later use to obtain a mixture B;

(iii) pumping the mixture B into a vacuum emulsifying pot for emulsification, pumping the mixture A into the vacuum emulsifying pot, stirring uniformly, adding 0.2kg polyacrylamide, 0.1kg C13-14 isoparaffin, 0.03kg laureth-7, 0.15kg water and 0.01kg arginine, homogenizing for 3min, then stirring at constant temperature for 20min, cooling, adding 6kg Hamamelis virginiana liquid, 0.1kg prickly ash fruit extract, 0.13kg capsicum frutescens fruit extract, 0.1kg kava root extract, 0.12kg Kushen root extract, 0.01kg p-hydroxyacetophenone, 0.01kg 1, 2-hexanediol, 0.3kg butanediol, 3kg water, 0.8kg loquat leaf extract, 0.5kg phellodendron bark extract, 0.3kg Artemisia capillaris thunbergii plant liquid, 0.25kg mulberry root bark extract, 0.14kg Glycyrrhiza glabra root extract, 0.03kg butanediol, 0.03kg glycerin, 1.5kg hexanediol, 0.5kg camphor tree bark extract, 0.4kg Litsea cubeba extract, 0.3kg rhizome artemisia officinalis plant liquid, 0.25kg sanguinea bark extract, 0.4kg of 1, 2-hexanediol, 0.04kg of quaternary ammonium salt-73 and 0.07kg of essence, continuously and fully stirring, and sequentially cooling, discharging, standing, inspecting, filling, packaging, code spraying, spot inspection and warehousing after the completion to obtain the acne removing cream.

Example 2

(1) drying loquat leaves, and crushing the loquat leaves to 70 meshes to obtain loquat leaf powder;

(2) mixing the loquat leaf powder obtained in the step (1) with distilled water according to the weight ratio of 1:2, heating and refluxing for 2 hours at 94 ℃, and filtering primary filter residue and primary extracting solution after the heating and refluxing are finished;

(3) mixing the primary filter residue obtained in the step (2) with ethanol according to the weight ratio of 1:4, heating and refluxing for 6 hours at 72 ℃, and filtering the secondary filter residue and the secondary extracting solution after the heating and refluxing are finished;

(4) mixing the primary extractive solution and the secondary extractive solution to obtain a mixed solution, concentrating to 1/3 of the original volume, and drying at 50 deg.C to obtain folium Eriobotryae extract.

(II) preparing the acne-removing cream, which comprises the following steps:

(i) stirring 5.5kg of cyclopentadimethylsiloxane, 4.5kg of ethylhexyl palmitate, 3.7kg of cetearyl alcohol, 2.5kg of cetearyl glucoside, 2kg of laurocapram, 1kg of polydimethylsiloxane and 0.5kg of menthol at 80 ℃, and preserving heat for later use after fully mixing to obtain a mixture A;

(ii) stirring 4.5kg of propylene glycol, 0.7kg of p-hydroxyacetophenone, 0.12kg of carbomer, 0.06kg of xanthan gum, 0.3kg of allantoin, 0.06kg of disodium EDTA and 65kg of water at 80 ℃, fully mixing, and keeping the temperature for later use to obtain a mixture B;

(iii) pumping the mixture B into a vacuum emulsifying pot for emulsification, pumping the mixture A into the vacuum emulsifying pot, stirring uniformly, adding 0.3kg polyacrylamide, 0.2kg C13-14 isoparaffin, 0.04kg laureth-7, 0.2kg water and 0.03kg arginine, homogenizing for 5min, then stirring at constant temperature for 20min, cooling, adding 10kg Hamamelis virginiana liquid, 0.15kg prickly ash fruit extract, 0.15kg capsicum fruit extract, 0.11kg kava root extract, 0.14kg radix Sophorae Flavescentis extract, 0.03kg p-hydroxyacetophenone, 0.03kg 1, 2-hexanediol, 0.35kg butanediol, 3.3kg water, 0.9kg loquat leaf extract, 0.7kg cork tree bark extract, 0.34kg artemisia capillaris rhizome plant liquid, 0.3kg mulberry root bark extract, 0.18kg Glycyrrhiza glabra root extract, 0.05kg butanediol, 2.05 kg glycerin, 2.5kg hexanediol, 0.6kg camphor tree bark extract, 0.6kg liquorice root extract, 0.6kg artemisia scopolia root extract, 0.03kg rhizome plant liquid, 0.3kg of 1, 0.15kg of hydrangea, 0.6kg of 1, 2-hexanediol, 0.06kg of quaternary ammonium salt-73 and 0.09kg of essence, continuously and fully stirring, and sequentially cooling, discharging, standing, inspecting, filling, packaging, code spraying, spot inspection and warehousing after the completion to obtain the acne removing cream.

Example 3

(1) drying loquat leaves, and crushing the loquat leaves to obtain loquat leaf powder with the granularity of 60 meshes;

(2) mixing the loquat leaf powder obtained in the step (1) with distilled water according to the weight ratio of 1:1.5, heating and refluxing for extraction for 1.5h at the temperature of 92 ℃, and filtering primary filter residue and primary extracting solution after the extraction is finished;

(3) mixing the primary filter residue obtained in the step (2) with ethanol according to the weight ratio of 1:3, heating and refluxing for extraction for 5 hours at 70 ℃, and filtering secondary filter residue and secondary extracting solution after the extraction is finished;

(4) mixing the primary extractive solution and the secondary extractive solution to obtain a mixed solution, concentrating to 1/4 of the original volume, and drying at 45 deg.C to obtain folium Eriobotryae extract.

(II) preparing the acne-removing cream, which comprises the following steps:

(i) stirring 5kg of cyclopentadimethylsiloxane, 4kg of ethylhexyl palmitate, 3.6kg of cetearyl alcohol, 2.4kg of cetearyl glucoside, 1.5kg of laurocapram, 0.8kg of polydimethylsiloxane and 0.4kg of menthol at 77 ℃, fully mixing and keeping the temperature for later use to obtain a mixture A;

(ii) stirring 4kg of propylene glycol, 0.5kg of p-hydroxyacetophenone, 0.1kg of carbomer, 0.05kg of xanthan gum, 0.2kg of allantoin, 0.05kg of disodium EDTA and 60kg of water at 77 ℃, and preserving heat for later use after fully mixing to obtain a mixture B;

(iii) pumping the mixture B into a vacuum emulsifying pot for emulsification, pumping the mixture A into the vacuum emulsifying pot, stirring uniformly, adding 0.25kg of polyacrylamide, 0.15kg of C13-14 isoparaffin, 0.035kg of laureth-7, 0.18kg of water and 0.02kg of arginine, homogenizing for 4min, then stirring at constant temperature for 20min, cooling, adding 8kg of Hamamelis virginiana liquid, 0.12kg of zanthoxylum bungeanum fruit extract, 0.14kg of capsicum frutescens fruit extract, 0.105kg of kava root extract, 0.13kg of Sophora flavescens root extract, 0.02kg of p-hydroxyacetophenone, 0.02kg of 1, 2-hexanediol, 0.32kg of butanediol, 3.15kg of water, 0.85kg of loquat leaf extract, 0.6kg of Berberis amurensis bark extract, 0.32kg of Artemisia capillaris thunbergii plant liquid, 0.27kg of mulberry root bark extract, 0.16kg of Glycyrrhiza glabra root extract, 0.04kg of butanediol, 0.04kg of hexanediol, 2kg of hexanediol extract, 0.5kg of Cinnamom, 0.5kg of 1, 2-hexanediol, 0.05kg of quaternary ammonium salt-73 and 0.08kg of essence, continuously and fully stirring, and then sequentially cooling, discharging, standing, inspecting, filling, packaging, spraying codes, performing spot inspection and warehousing to obtain the acne removing cream.

Sensory, physicochemical and sanitary standards are set by referring to QB/T1645-2004 and are used for detecting the acne-removing cream disclosed by the invention, the detection standards are shown in Table 1, and the detection results are shown in Table 2.

TABLE 1 organoleptic, physicochemical and hygienic standards

TABLE 2 sensory, physicochemical, and hygiene test results

Results and conclusions:

the acne removing cream obtained in the embodiment 1-3 meets the relevant requirements of the standard.

In order to detect the irritation of the acne-removing cream, a skin patch test and a chick embryo chorioallantoic membrane test are also performed with emphasis.

The method of the skin patch test is as follows: 15 healthy volunteers were selected, and the acne cream of the invention was applied to the back skin of 20 volunteers for a 48-hour closed class test, with the results shown in table 3.

TABLE 3 Patch test results

Group of	Example 1	Example 2	Examples3
				Results	Has no irritation	Has no irritation	Has no irritation

Method of chick embryo chorioallantoic membrane test the acne cream of the present invention was formulated into 0.1%, 0.5% and 0.8% aqueous solutions, respectively, and tested according to the technique disclosed in french official gazette at 26 th 12 th 1996, and the results are shown in table 4.

TABLE 4 chick embryo chorioallantoic Membrane test results

Note a: a test result of 0 indicates no irritation at this concentration.

Results and conclusions: the anti-acne cream patch test and the chick embryo chorioallantoic membrane test obtained in examples 1 to 3 both show no irritation.

In order to detect the acne removing effect of the acne removing cream, 20 volunteers with acne on face are selected, wherein 10 men and 10 women are selected.

The specific detection method comprises the following steps: the face of each volunteer was equally divided into A, B regions on average, and A, B regions showed similar whelk distribution. Each volunteer cleans the face once in the morning and at night, and after cleaning the face, the acne-removing cream disclosed by the invention is used for smearing an area A, while an area B is not smeared for 30 days. The results are shown in Table 5.

TABLE 5 acne removing Effect

Results and discussion:

the acne-removing cream disclosed by the invention has an extremely obvious curing effect on acne.

In order to detect the bacteriostatic effect of the acne cream, a bacteriostatic test is carried out, and the method comprises the following steps:

the acne cream is prepared into a solution to be detected for later use, then a sterilized solid culture medium is heated to be molten, and when the temperature is cooled to 50 ℃, every 20ml of culture tool is poured into a sterile culture dish. After the plate is naturally dried, 0.1ml of solution to be tested and 0.1ml of test bacterium suspension (propionibacterium acnes, malassezia furfur, staphylococcus epidermidis, escherichia coli and lactobacillus) are respectively transferred and evenly smeared on a dosing plate; a control group was set up and smeared with an equal amount of sterile water instead of the test solution. And (3) culturing the prepared bacterial plate at the constant temperature of 37 ℃ for 24h, counting the number of colonies, and calculating the bacteriostasis rate according to the following formula.

The bacteriostasis rate is × 100 percent (the number of control colonies-the number of treated colonies)/the number of control colonies

The results of the experiment are shown in Table 6.

TABLE 6 results of bacteriostatic experiments

The results show that: the acne-removing cream disclosed by the invention has an excellent antibacterial effect on escherichia coli, staphylococcus aureus and lactobacillus.

The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims

1. The acne-removing cream is characterized by comprising a component A, a component B, a component C and a component D; the component A comprises the following raw materials in parts by weight: 4.5-5.5 parts of cyclopentadimethylsiloxane, 3.5-4.5 parts of ethylhexyl palmitate, 3.5-3.7 parts of cetearyl alcohol, 2.3-2.5 parts of cetearyl glucoside, 1-2 parts of laurocapram, 0.6-1.0 part of polydimethylsiloxane and 0.3-0.5 part of menthol; the component B comprises the following raw materials in parts by weight: 3.5-4.5 parts of propylene glycol, 0.3-0.7 part of p-hydroxyacetophenone, 0.08-0.12 part of carbomer, 0.04-0.06 part of xanthan gum, 0.1-0.3 part of allantoin, 0.04-0.06 part of EDTA disodium and 55-65 parts of water; the component C comprises the following raw materials in parts by weight: 0.2-0.3 part of polyacrylamide, 0.1-0.2 part of C13-14 isoparaffin, 0.32-0.04 part of laureth-70.03, 0.15-0.2 part of water and 0.01-0.03 part of arginine; the component D comprises the following raw materials in parts by weight: 6-10 parts of witch hazel liquid, 0.1-0.15 part of zanthoxylum bungeanum fruit extract, 0.13-0.15 part of capsicum frutescens fruit extract, 0.1-0.11 part of kava root extract, 0.12-0.14 part of sophora flavescens root extract, 0.01-0.03 part of p-hydroxyacetophenone, 0.01-0.03 part of 1, 2-hexanediol, 0.3-0.35 part of butanediol, 3-3.3 parts of water, 0.8-0.9 part of loquat leaf extract, 0.5-0.7 part of phellodendron bark extract, 0.3-0.34 part of artemisia capillaris plant liquid, 0.25-0.3 part of mulberry root extract, 0.14-0.18 part of glycyrrhiza glabra root extract, 0.03-0.05 part of butanediol, 0.03-0.05 part of glycerin, 1.5-2.5 parts of hexanediol, 0.4 part of camphor tree extract, 0.6-0.6 part of glycyrrhiza glabra root extract, 0.6-0.09 part of hexanediol root extract, 0.06 part of essence, 0.09-0.06 part of hexanediol essence, and 0.09-0.06 part of.

2. The acne cream according to claim 1, comprising component A, component B, component C and component D; the component A comprises the following raw materials in parts by weight: 5 parts of cyclopenta dimethyl silicone polymer, 4 parts of ethylhexyl palmitate, 3.6 parts of cetearyl alcohol, 2.4 parts of cetearyl glucoside, 1.5 parts of laurocapram, 0.8 part of polydimethylsiloxane and 0.4 part of menthol; the component B comprises the following raw materials in parts by weight: 4 parts of propylene glycol, 0.5 part of p-hydroxyacetophenone, 0.1 part of carbomer, 0.05 part of xanthan gum, 0.2 part of allantoin, 0.05 part of EDTA disodium and 60 parts of water; the component C comprises the following raw materials in parts by weight: 0.25 part of polyacrylamide, 0.15 part of C13-14 isoparaffin, 0.18 part of laureth-70.035 part of water and 0.02 part of arginine; the component D comprises the following raw materials in parts by weight: 8 parts of witch hazel liquid, 0.12 part of zanthoxylum bungeanum fruit extract, 0.14 part of capsicum frutescens fruit extract, 0.105 part of kava root extract, 0.13 part of sophora flavescens root extract, 0.02 part of p-hydroxyacetophenone, 0.02 part of 1, 2-hexanediol, 0.32 part of butanediol, 3.15 parts of water, 0.85 part of loquat leaf extract, 0.6 part of phellodendron bark extract, 0.32 part of artemisia capillaris thunbergii plant liquid, 0.27 part of mulberry root bark extract, 0.16 part of glycyrrhiza glabra root extract, 0.04 part of butanediol, 0.04 part of glycerol, 2 parts of hexanediol, 0.5 part of camphor tree rhizome extract, 0.5 part of 1, 2-hexanediol, 0.78 part of quaternary ammonium salt-730.05 and 0.08 part of essence.

3. The acne cream according to claim 1 or 2, wherein the preparation method of the loquat leaf extract comprises the following steps:

(1) drying and crushing loquat leaves to obtain loquat leaf powder;

4. The acne cream according to claim 3, wherein in step (1), the grinding is carried out to a particle size of 50-70 meshes.

5. The acne cream according to claim 3, wherein in the step (2), the weight ratio of the loquat leaf powder to the distilled water is 1: 1-2; the heating reflux temperature is 90-94 ℃, and the extraction time is 1-2 h.

6. The acne cream according to claim 3, wherein in the step (3), the weight ratio of the primary filter residue to the ethanol is 1: 2-4; the heating reflux temperature is 68-72 ℃, and the extraction time is 4-6 h.

7. The acne cream according to claim 3, wherein in step (4), the acne cream is concentrated to 1/4-1/3; the drying temperature is 40-50 ℃.

8. The preparation method of the acne-removing cream disclosed by any one of claims 1-7 is characterized by comprising the following steps:

9. The preparation method of the acne cream according to claim 8, wherein in the steps (i) and (ii), the temperature of the heating and stirring is 75-80 ℃.

10. The preparation method of the acne cream according to claim 8, wherein in step (iii), the homogenization time is 3-5 min.