CN110420266A - A kind of three green pepper anti-acne anti-mite agent - Google Patents
A kind of three green pepper anti-acne anti-mite agent Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of three green pepper anti-acne anti-mite agent, mainly contain Chinese prickly ash (ZANTHOXYLUM BUNGEANUM) berry extract, millet starch (CAPSICUM FRUTESCENS) berry extract, kawakaw (PIPER METHYSTICUM) root extract.Three greens pepper acne-removing composition of the present invention can reduce fat secretion, guarantee that cuticula falls off normally, and also have good anti-mite effect, the problem of can effectively solve whelk recurrent exerbation.
Description
Technical field
The present invention relates to anti-acne anti-mite products, are specifically related to a kind of three green pepper anti-acne anti-mite agent.
Background technique
1841, mankind vermiform mite worm was found in people's external auditory canal by Berger earliest, was then presented as secrecy report
Give Paris academy of sciences；1842, G Simon published thesis in Berlin, is described in detail in find in human face's hair follicle this and posts
Infested is mite, and is called steatozoons.Later, constantly there are relevant research and discovery.1919, Stanley Hirst was first
The secondary monograph published about Demodex describes known 24 kinds of vermiform mites at that time.1972, C Desch and NB
Mankind vermiform mite worm is classified as demodex folliculorum and demodex brevis by Nutting.Mankind vermiform mite worm is found 177 years so far
Come, although not interrupted always to the researchs such as its biology, immunology, epidemiology, pathogenic, treatment method, due to doctor
Fatal disease will not generally be developed into clinical disease by treating bound pair demodicidosis ununified understanding and demodicidosis
Disease, or even many medical workers are additionally considered that mankind vermiform mite worm is exactly the non-pathogenic helminth of human normal.So that we
Medical text books do not discuss clearly, have less understanding after causing medico from one generation to the next to go on clinical position to it.
In face of whelk (acne), the acarodermatitis such as brandy nose, pore be coarse, blackhead, the change of skin orange peel, flush
Clinical manifestation, if treated still according to traditional fuzzy cause of disease, this results in clinically not curing acarodermatitis,
And there is basic reason repeatedly (referring to the clinical research of Pu Xingwang, Liu Gang, Lu Kaihua mankind vermiform mite worm and skin health
Be in progress [J] China drainer for plastic surgery magazine, 2018,29 (08): 510-511+516-517.)
Therefore, market in urgent need one kind had not only had anti-acne effect, but also the product with mite removal effect, was sent out repeatedly with solving whelk
Make, it is difficult to the problem of eradicating.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of product for resolving poxes for having both mite removal effect, can effectively solve the youth
The problem of acne recurrent exerbation.
The specific technical solution to solve the above problems is as follows:
A kind of three green pepper anti-acne anti-mite agent, contain Chinese prickly ash (ZANTHOXYLUM BUNGEANUM) berry extract, millet starch
(CAPSICUM FRUTESCENS) berry extract, kawakaw (PIPER METHYSTICUM) root extract.
Three greens pepper anti-acne anti-mite agent of the present invention can be prepared by conventional production process, in preferable implementation of the invention
In mode comprising following steps:
(1) Chinese prickly ash fruit, millet starch fruit, kawakaw root dry, pulverize to 10-50 mesh, obtains plant powder；
(2) water, butanediol, hexylene glycol are added into plant powder to extract as Extraction solvent, then filters.
In wherein some embodiments, in the step (2), extracts preferred cryogenic high pressure difference method and extract, including walk as follows
Rapid: by plant powder and solvent, investment is extracted in kettle together after mixing, and temperature is adjusted to 30 ~ 50 DEG C, it is forced into 50 ~
100MPa, stirs lower soak extraction 10 ~ 30 minutes, is then centrifuged for, then collection supernatant is separated by filtration.
In wherein some embodiments, the Chinese prickly ash fruit, millet starch fruit, kawakaw root mass ratio be (1-
10): (1-10): (1-10).
The mass ratio of Chinese prickly ash fruit, millet starch fruit, kawakaw root described in one of the embodiments, is 1:2:1.
In wherein some embodiments, the mass ratio of the plant powder and water, butanediol, hexylene glycol is 1:15:
5:0.5。
The present invention uses the characteristics of cryogenic high pressure difference method to be to be avoided that the loss of heat-sensitive ingredients, high-pressure section under cryogenic conditions
Solvent is easier to penetrate into inside plant powder under part, is quickly soluble in effective component in solvent, and test proves, passes through low temperature
The extract active constituent that High Pressure Difference method obtains is higher, and skin-care effect is more preferably.
Three greens pepper acne-removing composition of the present invention can reduce fat secretion, guarantee that cuticula falls off normally, and also
With good anti-mite effect, the problem of can effectively solve whelk recurrent exerbation, can be used as a kind of activated feedstock and be added to
The common matrix of skin care item or carrier can be made into anti-acne cream, anti-acne essence, anti-acne aqua, anti-acne jelly, Deacne pack, dispel
The cosmetics such as acne is spraying, acarid of dispelling is spraying.
In wherein some embodiments, usage amount of the three green pepper acne-removing compositions in cosmetics is 1-10wt%.
The embodiment of the invention also provides a kind of oil control and acne removal frost, the component including following mass percentage:
In wherein some embodiments, the oil control and acne removal frost also contains the extraction of kuh-seng (SOPHORA ANGUSTIFOLIA) root
Object.
Kuh-seng (SOPHORA ANGUSTIFOLIA) root extract of the present invention can be marketable material, be also possible to
Be made by conventional method, such as: be solvent with water or ethyl alcohol, extract 1-3 time, combined extract, filter to get.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
Chinese prickly ash fruit according to the present invention, to A type and beta streptococcus, staphylococcus, pneumococcus, bacillus anthracis, withered
Straw bacterium, comma bacillus, proteus, paratyphosum Bacterium, shigella dysenteriae, Pseudomonas aeruginosa have inhibiting effect.Volatile oil is to thin
Bacterium and a variety of dermatophytes and deep fungal have certain bacteriostasis, wherein to wool sample sporidiole bacteria and red hair tinea
Bacterium is most sensitive.Skimmianine also has stronger antifungic action.Contained volatile oil can make ascaris suum seriously be poisoned in ringer solution, right
Itch mite has stronger action of contace poison.
Millet starch fruit according to the present invention, to many strains such as gold-coloured staphylococci, Fu Shi dysentery bacterium, typhoid fever dysentery bacterium, green
Purulence bacillus, withered grass bacterium etc. have the killing effect of inhibition, while can also accelerate blood circulation, promote red blood cell liveness, accelerate
Skin metabolism helps impaired organization healing and consolidation skin, can promote close connection between epidermis and corium and
It can inhibit the increase of fat cell.
Kawakaw root according to the present invention contains a variety of amides compounds: such as piperine, piperamide, piperettine
Alkali, papper oil alkali, aromatic oil, crude protein etc. compound are directed to the propionibacterium acnes of small pox, pseudomonas aeruginosa, and white is read
Pearl bacterium and staphylococcus have extraordinary sterilization analgesic activity.
Radix sophorae according to the present invention, rich in matrine, oxymatrine, ammothamnine, N-Methylcytisine,
The alkaloids such as Anagyrine, baptifoline, SopHocarpine, d-Iosmatrine, Kuraridine have anti-inflammation and sterilization antibacterial, adjust
Immune and increasing leukocyte and Bergamot Mint Extract.
Embodiment 1
A kind of preparation method of three greens pepper anti-acne anti-mite agent, comprising the following steps:
(1) Chinese prickly ash fruit, millet starch fruit, kawakaw root is dry, wherein the Chinese prickly ash fruit, millet starch fruit, kawakaw root
Mass ratio be 1:10:1；50 mesh are crushed to, plant powder is obtained；
(2) water, butanediol, hexylene glycol are added into plant powder, wherein the plant powder and water, butanediol, hexylene glycol
Mass ratio be 1:15:5:0.5；Investment is extracted in kettle together after mixing, and temperature is adjusted to 30 DEG C, is forced into
50MPa is stirred lower soak extraction 30 minutes, is then centrifuged for, collects supernatant, then with the separation of 1000 mesh filter-cloth filterings.
Embodiment 2
A kind of preparation method of three greens pepper anti-acne anti-mite agent, comprising the following steps:
(1) Chinese prickly ash fruit, millet starch fruit, kawakaw root is dry, wherein the Chinese prickly ash fruit, millet starch fruit, kawakaw root
Mass ratio be 10:1:10；10 mesh are crushed to, plant powder is obtained；
(2) water, butanediol, hexylene glycol are added into plant powder, wherein the plant powder and water, butanediol, hexylene glycol
Mass ratio be 1:15:5:0.5；Investment is extracted in kettle together after mixing, and temperature is adjusted to 50 DEG C, is forced into
100MPa is stirred lower soak extraction 10 minutes, is then centrifuged for, collects supernatant, then with the separation of 500 mesh filter-cloth filterings.
Embodiment 3
A kind of preparation method of three greens pepper anti-acne anti-mite agent, comprising the following steps:
(1) Chinese prickly ash fruit, millet starch fruit, kawakaw root is dry, wherein the Chinese prickly ash fruit, millet starch fruit, kawakaw root
Mass ratio be 1:2:1；30 mesh are crushed to, plant powder is obtained；
(2) water, butanediol, hexylene glycol are added into plant powder, wherein the plant powder and water, butanediol, hexylene glycol
Mass ratio be 1:15:5:0.5；Investment is extracted in kettle together after mixing, and temperature is adjusted to 40 DEG C, is forced into
80MPa is stirred lower soak extraction 20 minutes, is then centrifuged for, collects supernatant, then with the separation of 800 mesh filter-cloth filterings.
Comparative example 1
A kind of preparation method of three greens pepper anti-acne anti-mite agent, comprising the following steps:
(1) Chinese prickly ash fruit is crushed to 30 mesh, obtains plant powder；
(2) water, butanediol, hexylene glycol are added into plant powder, wherein the plant powder and water, butanediol, hexylene glycol
Mass ratio be 1:15:5:0.5；Investment is extracted in kettle together after mixing, and temperature is adjusted to 40 DEG C, is forced into
80MPa is stirred lower soak extraction 20 minutes, is then centrifuged for, collects supernatant, then with the separation of 800 mesh filter-cloth filterings.
Comparative example 2
A kind of preparation method of three greens pepper anti-acne anti-mite agent, comprising the following steps:
(1) millet starch fruit powder is broken to 30 mesh, obtains plant powder；
(2) water, butanediol, hexylene glycol are added into plant powder, wherein the plant powder and water, butanediol, hexylene glycol
Mass ratio be 1:15:5:0.5；Investment is extracted in kettle together after mixing, and temperature is adjusted to 40 DEG C, is forced into
80MPa is stirred lower soak extraction 20 minutes, is then centrifuged for, collects supernatant, then with the separation of 800 mesh filter-cloth filterings.
Comparative example 3
A kind of preparation method of three greens pepper anti-acne anti-mite agent, comprising the following steps:
(1) kawakaw root is crushed to 30 mesh, obtains plant powder；
(2) water, butanediol, hexylene glycol are added into plant powder, wherein the plant powder and water, butanediol, hexylene glycol
Mass ratio be 1:15:5:0.5；Investment is extracted in kettle together after mixing, and temperature is adjusted to 40 DEG C, is forced into
80MPa is stirred lower soak extraction 20 minutes, is then centrifuged for, collects supernatant, then with the separation of 800 mesh filter-cloth filterings.
Comparative example 4
A kind of preparation method of three greens pepper anti-acne anti-mite agent, comprising the following steps:
(1) Chinese prickly ash fruit, millet starch fruit, kawakaw root is dry, wherein the Chinese prickly ash fruit, millet starch fruit, kawakaw root
Mass ratio be 1:2:1；30 mesh are crushed to, plant powder is obtained；
(2) water, butanediol, hexylene glycol are added into plant powder, wherein the plant powder and water, butanediol, hexylene glycol
Mass ratio be 1:15:5:0.5；Investment is extracted in kettle together after mixing, soaking at room temperature extraction 20 minutes under stirring, so
After be centrifuged, collect supernatant, then with 800 mesh filter-cloth filterings separation.
Test the test of 1 anti-mite
(1) acquisition of human Demodex: vermiform mite is obtained using Transparent spinel, specific steps: before advising subject to sleep
After washing one's face, by long 6cm, the adhesive tape of wide 1.5cm is affixed on the positions such as volume, cheek, nose, chin respectively, morning next day take off after stick at
Adhesive tape, microscopy.
(2) it test grouping: takes water as a solvent, is respectively diluted to extract obtained by embodiment 1-3 and comparative example 1-4
1% dilution, and blank control is set.200 microlitres of 1% dilution is added dropwise in each glass slide, spreads out dilution uniformly, guarantees dilute
Liquid is released to come into full contact with polypide.It is placed in the environment that relative humidity is 70-80%, temperature is 26-28 DEG C, is taken out after 1 hour, shown
The survival condition of micro- microscopic observation vermiform mite.3min is observed continuously under 400 × microscope, polypide huge legendary turtle limb or the sufficient motionless person of pawl sentence
Break as death.It specifically tests several such as the following table 1.
1 anti-mite test recording table of table
Seen from table 1, anti-mite effect is best when Chinese prickly ash fruit, millet starch fruit, kawakaw root share.
Embodiment 4
A kind of oil control and acne removal frost, the component including following mass percentage:
。
Embodiment 5
A kind of oil control and acne removal frost, the component including following mass percentage:
。
Embodiment 6
A kind of oil control and acne removal frost, the component including following mass percentage:
。
Embodiment 7
A kind of oil control and acne removal frost, the component including following mass percentage:
Kuh-seng (SOPHORA ANGUSTIFOLIA) root extract of the present invention is made by the following method, such as: it uses
75vt% ethyl alcohol is solvent, stir it is lower extract 3 times, combined extract, filtering to get.
Test the test of 2 oil control and acne removals
The assessment of oil-control effect is carried out to oil control and acne removal frost obtained by embodiment 4-7 and blank control group.Wherein blank control group
Difference with embodiment 6 is without containing three green pepper anti-acne anti-mite agent.
Test equipment: German CK company skin oil and fat tester Sebumeter SM815.Its working principle is to use
A kind of special adhesive tape, can quickly absorb keratoderma surface grease, and grease can make the light transmittance of adhesive tape change, pass through instrument
The light transmittance before and after photometer measurement adhesive tape use built in device and the fat content for obtaining keratoderma.
Test method: convening 40 Oilys and the volunteer with whelk, is divided into 4 groups, every group of 10 people are early daily
Evening respectively uses an oil control and acne removal frost, and usage amount is 0.1g/ times, is applied on the face, is gently massaged into absorption.It took pictures every 1 week
Recording an anti-acne situation, (by comparing with the photo before product is used, the judgement that whelk quantity reduces 1/3 or more is to have
Effect), and the fat content at volunteer's forehead position is measured with skin oil and fat tester, each site tests 3 times are averaged.
Specific test record such as the following table 2, table 3.
2 oil-control test recording table of table
3 anti-acne test recording table of table
From table 2, table 3 as it can be seen that oil control and acne removal frost obtained by the embodiment of the present invention has good oil control and acne removal effect.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.
Claims (9)
1. a kind of three green pepper anti-acne anti-mite agent, which is characterized in that containing Chinese prickly ash (ZANTHOXYLUM BUNGEANUM) berry extract,
Millet starch (CAPSICUM FRUTESCENS) berry extract, kawakaw (PIPER METHYSTICUM) root extract.
2. a kind of preparation method of three greens pepper anti-acne anti-mite agent as described in claim 1, which comprises the following steps:
(1) Chinese prickly ash fruit, millet starch fruit, kawakaw root dry, pulverize to 10-50 mesh, obtains plant powder；
(2) water, butanediol, hexylene glycol are added into plant powder to extract as Extraction solvent, then filters.
3. the preparation method of three greens pepper anti-acne anti-mite agent according to claim 2, which is characterized in that in the step (2), mention
It takes preferred cryogenic high pressure difference method to extract, includes the following steps: that investment extracts kettle together after mixing by plant powder and solvent
In, temperature is adjusted to 30 ~ 50 DEG C, is forced into 50 ~ 100MPa, stirs lower soak extraction 10 ~ 30 minutes, is then centrifuged for, collection
Then supernatant is separated by filtration.
4. the preparation method of three greens pepper anti-acne anti-mite agent according to claim 2, which is characterized in that the Chinese prickly ash fruit, small
Meter Jiao Guo, kawakaw root mass ratio be (1-10): (1-10): (1-10).
5. the preparation method of three greens pepper anti-acne anti-mite agent according to claim 2, which is characterized in that the Chinese prickly ash fruit, small
Meter Jiao Guo, kawakaw root mass ratio be 1:2:1.
6. the preparation method of three greens pepper anti-acne anti-mite agent according to claim 2, which is characterized in that the plant powder with
Water, butanediol, hexylene glycol mass ratio be 1:15:5:0.5.
7. application of the three greens pepper anti-acne anti-mite agent described in claim 1 in cosmetics.
8. a kind of oil control and acne removal frost, which is characterized in that the component including following mass percentage:
。
9. oil control and acne removal frost according to claim 8, which is characterized in that further include kuh-seng (SOPHORA
ANGUSTIFOLIA) root extract.
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Cited By (9)
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| CN111329807A (en) * | 2020-04-02 | 2020-06-26 | 广州市逸轩精细化工有限公司 | Acne removing cream and preparation method thereof |
| CN111617010A (en) * | 2020-07-23 | 2020-09-04 | 广州市轩颜化妆品有限公司 | Foot periostracum and preparation method thereof |
| CN111991302A (en) * | 2020-09-23 | 2020-11-27 | 广东大澳生物科技有限公司 | Acne removing gel and preparation method thereof |
| CN112006934A (en) * | 2020-09-04 | 2020-12-01 | 江苏美爱斯化妆品股份有限公司 | Cosmetic compound with mild acne removing effect and application thereof |
| CN113197804A (en) * | 2021-04-29 | 2021-08-03 | 钟意生物技术(广州)有限公司 | Plant repair factor and application thereof |
| CN113208992A (en) * | 2021-05-11 | 2021-08-06 | 广州杨森药业有限公司 | Mild acne-removing mite-removing goat milk soap and preparation method thereof |
| CN115006314A (en) * | 2022-07-11 | 2022-09-06 | 科乐美(广州)生物科技有限公司 | Piper methysticum Forst extract and its preparation method and application |
| WO2024052756A1 (en) * | 2022-09-09 | 2024-03-14 | Crodarom | Use of an extract of sichuan pepper for a skin treatment and a composition suitable for this use. |
| FR3139466A1 (en) * | 2022-09-09 | 2024-03-15 | Crodarom | Use of a Sichuan pepper extract for skin treatment and a composition adapted to this use. |
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| CN111617010A (en) * | 2020-07-23 | 2020-09-04 | 广州市轩颜化妆品有限公司 | Foot periostracum and preparation method thereof |
| CN112006934A (en) * | 2020-09-04 | 2020-12-01 | 江苏美爱斯化妆品股份有限公司 | Cosmetic compound with mild acne removing effect and application thereof |
| CN111991302A (en) * | 2020-09-23 | 2020-11-27 | 广东大澳生物科技有限公司 | Acne removing gel and preparation method thereof |
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| CN115006314B (en) * | 2022-07-11 | 2023-07-11 | 科乐美(广州)生物科技有限公司 | Kava pepper extract and preparation method and application thereof |
| WO2024052756A1 (en) * | 2022-09-09 | 2024-03-14 | Crodarom | Use of an extract of sichuan pepper for a skin treatment and a composition suitable for this use. |
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