CN111991302A - Acne removing gel and preparation method thereof - Google Patents

Abstract

The invention discloses an acne-removing gel which is prepared from the following components in parts by weight: 60-70 parts of water, 5-10 parts of three-pepper composition, 4-8 parts of melaleuca alternifolia leaf water, 0.5-3 parts of potassium azeloyl diglycoate, 0.5-2 parts of radix gentianae extract, 0.5-2 parts of quaternary ammonium salt-730.5-3 parts, 0.5-2 parts of purslane extract composition, 0.05-1 part of melaleuca alternifolia leaf oil, 0.01-1 part of citrus junos fruit oil, 10-20 parts of humectant, 0.5-2 parts of solubilizer, 0.3-1.5 parts of thickener, 0.3-1.5 parts of antioxidant, 0.3-1.5 parts of pH regulator and 0.001-0.5 part of colorant. The acne-removing gel is prepared by adding various skin conditioners on the basis of the three-pepper composition and matching with a humectant, a solubilizer, a thickening agent, an antioxidant, a pH regulator and a coloring agent, so that the mite and acne removing effects are obviously improved, and the gel is mild and has no stimulation.

Description

Acne removing gel and preparation method thereof

Technical Field

The invention relates to the technical field of skin care products, and particularly relates to an acne-removing gel and a preparation method thereof.

Background

Acne, also known as whelk, is a chronic inflammation of hair follicles and sebaceous glands, and mainly occurs in the areas of face, chest and back and other fatty areas. The sebaceous glands of acne patients are large, the secretion products of the sebaceous glands are more than normal people, the secretion of the sebaceous glands is increased, the linoleic acid level in sebum is relatively reduced, the synthesis of fat is influenced, and the follicular epithelium lacks fatty acid, so that the follicular hyperkeratosis is induced, epithelial cells cannot normally fall off, the follicular orifice is excessively reduced, the sebum cannot be smoothly discharged, and the sebum is deposited at the follicular orifice to form acne. The research on acne-removing products is not lacked in the market. The composition of the three-pepper (zanthoxylum bungeanum maxim extract, capsicum frutescens maxim extract and kava root extract) has good effect of removing mites and acnes, and is approved by many consumers. The application is based on further research on the three-pepper composition and is an improved invention based on the three-pepper composition. Specifically, the three-pepper composition is added with other acne-removing components, so that the components act synergistically, and the acne-removing composition can be obviously improved in the aspects of mite and acne removing effects and the like.

Disclosure of Invention

In order to overcome the defects of the prior art, the invention aims to provide an acne removing gel,

the second purpose of the invention is to provide a preparation method of the acne-removing gel,

one of the purposes of the invention is realized by adopting the following technical scheme:

the acne removing gel is prepared from the following components in parts by weight:

60-70 parts of water, 5-10 parts of three-pepper composition, 4-8 parts of melaleuca alternifolia leaf water, 0.5-3 parts of potassium azeloyl diglycoate, 0.5-2 parts of radix gentianae extract, 0.5-2 parts of quaternary ammonium salt-730.5-3 parts, 0.5-2 parts of purslane extract composition, 0.05-1 part of melaleuca alternifolia leaf oil, 0.01-1 part of citrus junos fruit oil, 10-20 parts of humectant, 0.5-2 parts of solubilizer, 0.3-1.5 parts of thickener, 0.3-1.5 parts of antioxidant, 0.3-1.5 parts of pH regulator and 0.001-0.5 part of colorant.

Further, the three-pepper composition consists of a zanthoxylum bungeanum fruit extract, a sophora flavescens root extract, a capsicum frutescens extract, a kava root extract, p-hydroxyacetophenone, 1, 2-hexanediol and butanediol.

Further, the purslane extract composition consists of water, butylene glycol, and a purslane extract.

Further, the humectant consists of butylene glycol, glycerin, erythritol, sodium hyaluronate and 1, 2-hexanediol.

Further, the solubilizer is PEG-40 hydrogenated castor oil; the thickening agent is carbomer and polyacrylate cross-linked polymer-6; the antioxidant is p-hydroxyacetophenone; the pH regulator is arginine.

Further, the color numbers of the colorants are CI 74260 and CI 42090.

Further, the composition is prepared from the following components in parts by weight: 60-70 parts of water, 5-10 parts of a sanjiao composition, 4-8 parts of melaleuca alternifolia leaf water, 0.5-3 parts of potassium azelaidate, 0.5-2 parts of radix gentianae extract, 0.5-2 parts of a quaternary ammonium salt-730.5-3 parts, 0.5-2 parts of a purslane extraction composition, 0.05-1 part of melaleuca alternifolia leaf oil, 0.01-1 part of orange fruit oil, 7-10 parts of butanediol, 3-6 parts of glycerol, 0.5-2 parts of erythritol, 0.05-1 part of sodium hyaluronate, 0.1-1 part of 1, 2-hexanediol, 0.5-2 parts of PEG-40 hydrogenated castor oil, 0.1-1 part of carbomer, and 60.1-1 part of a polyacrylate cross-linked polymer, 0.3-1.5 parts of p-hydroxyacetophenone, 0.3-1.5 parts of arginine, 0.1-0.1 part of CI 742600.0001 and 0.1 part of CI 420900.00001.

Further, the composition is prepared from the following components in parts by weight: 64.36 parts of water, 7 parts of a sanjiao composition, 6 parts of melaleuca alternifolia leaf water, 1.5 parts of potassium nonanedioyl diglycoate, 1 part of radix gentianae extract, 731 parts of quaternary ammonium salt, 1 part of a purslane extraction composition, 0.12 part of melaleuca alternifolia leaf oil, 0.03 part of orange fruit oil, 9 parts of butanediol, 4 parts of glycerol, 1.5 parts of erythritol, 0.09 part of sodium hyaluronate, 0.5 part of 1, 2-hexanediol, 1.2 parts of PEG-40 hydrogenated castor oil, 0.5 part of carbomer, 60.25 parts of polyacrylate cross-linked polymer, 0.5 part of p-hydroxyacetophenone, 0.45 part of arginine, CI 742600.00032 parts and CI 420900.00002 parts.

The second purpose of the invention is realized by adopting the following technical scheme:

a preparation method of the acne removing gel comprises the following steps:

preheating: heating the mixing pot to 80-85 ℃;

a primary material mixing step: adding water, humectant, thickener and antioxidant into the mixing pot, heating to 80-85 deg.C, stirring and homogenizing for 2-5min until all raw materials are completely dissolved, maintaining the temperature for 20-35min, and cooling to obtain a first mixture;

a secondary material mixing step: cooling the first mixture to 55-65 ℃, adding a pH regulator in a formula amount, and uniformly stirring to obtain a second mixture;

and a third mixing step: mixing the solubilizer, the melaleuca alternifolia leaf oil and the orange fruit oil according to the formula ratio, and uniformly dispersing to obtain a third mixture;

and a fourth material mixing step: cooling the second mixture to 40-50 ℃, adding a formula amount of three-pepper composition, melaleuca alternifolia leaf water, potassium azeloyl diglycolate, radix gentianae extract, quaternary ammonium salt-73, purslane extract composition and the third mixture, and uniformly stirring to obtain a fourth mixture;

color matching: gradually adding the colorant with the formula amount into the fourth mixture, and uniformly stirring;

cooling and discharging: sampling, inspecting, cooling after being qualified, filtering and discharging.

Furthermore, the temperature reduction operation involved in the preparation process is vacuum temperature reduction.

Compared with the prior art, the invention has the beneficial effects that:

(1) the acne removing gel provided by the invention is improved on the basis of the three-pepper composition, and the following skin conditioning agents are added: melaleuca alternifolia leaf water, potassium nonanedioyl diglycoate, radix gentianae extract, quaternary ammonium salt-73, purslane extract composition, melaleuca alternifolia leaf oil and orange fruit oil; and then the humectant, the solubilizer, the thickener, the antioxidant, the pH regulator and the colorant are further reasonably matched, so that the mite and acne removing effects are obviously improved, and the product is mild and has no stimulation.

(2) The preparation method of the acne-removing gel provided by the invention is simple in preparation process and easy to realize industrial production.

Drawings

Fig. 1 is a preparation flow chart of the acne removing gel provided in embodiment 1 of the invention.

Detailed Description

The present invention will be further described with reference to the accompanying drawings and the detailed description, and it should be noted that any combination of the embodiments or technical features described below can be used to form a new embodiment without conflict.

The acne removing gel is prepared from the following components in parts by weight:

60-70 parts of water, 5-10 parts of three-pepper composition, 4-8 parts of melaleuca alternifolia leaf water, 0.5-3 parts of potassium azeloyl diglycoate, 0.5-2 parts of radix gentianae extract, 0.5-2 parts of quaternary ammonium salt-730.5-3 parts, 0.5-2 parts of purslane extract composition, 0.05-1 part of melaleuca alternifolia leaf oil, 0.01-1 part of citrus junos fruit oil, 10-20 parts of humectant, 0.5-2 parts of solubilizer, 0.3-1.5 parts of thickener, 0.3-1.5 parts of antioxidant, 0.3-1.5 parts of pH regulator and 0.001-0.5 part of colorant.

The melaleuca alternifolia leaf water has strong transdermal penetration promoting effect, can help other effective components to be absorbed, and can be used as skin penetrating agent; has antibacterial and acarid removing effects, and can be used as antibacterial agent.

The potassium azelate diglycosite is a raw material for whitening and removing acnes, is an azelaic acid derivative, has good effects of regulating grease secretion, inhibiting skin seborrhea and removing skin acnes; competitively inhibiting tyrosinase activity, and whitening and removing speckle; can improve skin moisture-keeping ability and skin elasticity, and is safe and non-irritant.

The gentiana scabra bunge root extract can reduce the generation of pox, deeply repair the skin after pox, relieve the pox mark and restore the beautiful skin.

The quaternary ammonium salt-73 has strong antibacterial activity, can destroy the cell membrane of bacterial fungi, and has excellent effect on propionibacterium acnes; can also inhibit melanin formation; strong effect but extremely high safety.

The purslane extract contains alkaloid and flavone, can resist bacteria and inhibit common pathogenic dermatophytes, and has obvious itching relieving effect and antiallergic performance. The flavone and saponin contained in herba Portulacae have effects of scavenging free radicals and resisting oxidation, and can be used for delaying skin aging.

The melaleuca alternifolia leaf oil has strong transdermal penetration promoting effect, can help other effective components to be absorbed, and can be used as skin penetrating agent; has antibacterial and acarid removing effects, and can be used as antibacterial agent.

The orange fruit oil can regulate metabolism, enhance resistance, and discharge fat-soluble harmful substances.

As a further embodiment, the three-pepper composition consists of zanthoxylum bungeanum fruit extract, sophora flavescens root extract, capsicum frutescens extract, kava root extract, p-hydroxyacetophenone, 1, 2-hexanediol and butylene glycol.

The extract of Ophicalcitum fruit has inhibitory effect on Streptococcus A and B, Staphylococcus, pneumococcus, Bacillus anthracis, Bacillus subtilis, Vibrio cholerae, Bacillus proteus, Bacillus paratyphi, Bacillus dysenteriae, and Bacillus pyocyaneus. The volatile oil has antibacterial effect on bacteria, various dermatophytes and deep fungi, and is most sensitive to Microsporum lanuginosum and Trichophyton rubrum. Skimmianine also has strong antifungal effect. The contained volatile oil can cause serious poisoning of ascaris suum in the wilson fluid. The zanthoxylum bungeanum maxim fruit extract has stronger contact killing effect on scabies.

The capsicum frutescens extract is an active substance extracted from Capsicum annuum of Rutaceae, and has effects of removing acne marks, removing dark circles, relieving pain and diminishing inflammation. The antibacterial agent has the effects of inhibiting and killing a plurality of strains such as staphylococcus aureus, freund dysentery bacterium, typhoid dysentery bacterium, pseudomonas aeruginosa, bacillus subtilis and the like, and can accelerate blood circulation, promote the activity of red blood cells, accelerate skin metabolism, help injured tissues to heal and compact skin, promote close connection between epidermis and dermis and inhibit increase of fat cells.

The kava root extract is an active substance extracted from Capsicum annuum of Rutaceae, and has effects of relieving swelling and pain, removing acne, and relieving inflammation. The kava root extract contains various amide compounds: the compounds such as piperine, piperamide, piperine, piperoleine, aromatic oil, crude protein, etc. have excellent bactericidal and analgesic effects against Propionibacterium acnes, Pseudomonas aeruginosa, Candida albicans, and Staphylococcus aureus.

The radix Sophorae Flavescentis extract is an alkaloid extracted from radix Sophorae Flavescentis of Sophora of Leguminosae, and has antiinflammatory, antibacterial, immunity regulating, leukocyte increasing, and lipid secretion balancing effects. The radix Sophorae Flavescentis extract is rich in matrine, oxymatrine, hydroxymatrine, N-methyl cytisine, anabasine, baptidine, dehydromatrine, d-isomatrine, and kuraridine. Norkurarinone, kurarinol, new radix Sophorae Flavescentis, norkurarinol, isokurarinone, and formononetin. The acne removing cream has ideal acne removing effect on acne type acnes induced by sebum factors and follicular inflammation induced by bacterial factors.

As a further embodiment, the purslane extract composition consists of water, butylene glycol, and a purslane extract.

As a further embodiment, the moisturizer consists of butylene glycol, glycerin, erythritol, sodium hyaluronate, and 1, 2-hexanediol. The solubilizer is PEG-40 hydrogenated castor oil. The thickener is carbomer and polyacrylate cross-linked polymer-6. The antioxidant is p-hydroxyacetophenone. The pH regulator is arginine. The color numbers of the colorants were CI 74260 and CI 42090.

The acne removing gel provided by the embodiment of the invention is improved on the basis of the three-pepper composition, and the following skin conditioners are added: melaleuca alternifolia leaf water, potassium nonanedioyl diglycoate, radix gentianae extract, quaternary ammonium salt-73, purslane extract composition, melaleuca alternifolia leaf oil and orange fruit oil; and then the humectant, the solubilizer, the thickener, the antioxidant, the pH regulator and the colorant are further reasonably matched, so that the mite and acne removing effects are obviously improved, and the product is mild and has no stimulation.

Example 1

An acne removing gel is prepared from the components shown in table 1 by the following method:

a cleaning and disinfecting step: cleaning and disinfecting production equipment and tools;

preheating: heating the mixing pot to 80-85 ℃ for later use;

a primary material mixing step: adding water, butanediol, glycerol, erythritol, sodium hyaluronate, carbomer, 1, 2-hexanediol, p-hydroxyacetophenone and polyacrylate crosslinked polymer-6 into a mixing pot, heating to 80-85 ℃, stirring and homogenizing for 3min until all raw materials are completely dissolved, keeping the temperature for 30min, and performing vacuum cooling to obtain a first mixture;

a secondary material mixing step: when the first mixture is cooled to 60 ℃ in vacuum, adding arginine according to the formula amount, and uniformly stirring to obtain a second mixture;

and a third mixing step: mixing PEG-40 hydrogenated castor oil, melaleuca alternifolia leaf oil and orange fruit oil according to formula ratio, and dispersing uniformly to obtain a third mixture;

and a fourth material mixing step: cooling the second mixture to 45 ℃ in vacuum, adding the three-pepper composition, the melaleuca alternifolia leaf water, the potassium azelaidate, the radix gentianae extract, the quaternary ammonium salt-73, the purslane extract composition and the third mixture in formula amount, and uniformly stirring to obtain a fourth mixture;

color matching: gradually adding the formula amounts of CI 74260 and CI 42090 to the fourth mixture, and stirring uniformly;

cooling and discharging: sampling and inspecting, and filtering and discharging at low temperature after the product is qualified;

a storage and packaging step: and storing, filling and packaging the semi-finished product.

Table 1 example 1 formula of anti-acne gel

Examples 2 to 5

Examples 2-5 differ from example 1 in the amounts of components used in the formulations, as shown in table 2 below.

Table 2 examples 2-5 formulation tables for anti-acne gels

Comparative example 1

Comparative example 1 differs from example 1 in that: the formulation did not contain melaleuca alternifolia water, potassium azelaidate, gentian root extract, quaternary ammonium salt-73, purslane extract composition, melaleuca alternifolia oil, and citrus aurantium fruit oil, i.e., the skin conditioner of comparative example 1 was only a three pepper composition and did not contain the other skin conditioners of the formulation of example 1.

Comparative example 2

Comparative example 2 differs from example 1 in that the formulation does not contain melaleuca alternifolia water and melaleuca alternifolia oil, and is otherwise the same as example 1.

Comparative example 3

Comparative example 3 is different from example 1 in that the three-pepper composition is used in an amount of 3 parts, and the rest is the same as example 1.

Comparative example 4

Comparative example 4 is different from example 1 in that the moisturizers butylene glycol, glycerin, erythritol, sodium hyaluronate and 1, 2-hexanediol were not included in the formulation, and the rest was the same as example 1.

Effect evaluation and Performance detection

1. The samples of examples 1-5 were sent to a testing center, and 15 items of desloratadine, chlorpheniramine, astemizole, triamcinolone, brompheniramine and the like were tested according to the technical cosmetic safety standard (2015 edition), and the test results are shown in table 3 below.

TABLE 3 Desloratadine, chlorphenamine, etc. 15 items of test results recording table

As can be seen from the records in Table 3, the samples of examples 1-5 all reached the standard in 15 tests of desloratadine, chlorpheniramine, astemizole, triamcinolone acetonide, brompheniramine and the like, and the standard is met.

2. The samples of examples 1 to 5 were sent to a testing center and tested for glucocorticoids, sex hormones, and antibiotics, items 41 and 7, according to the technical standards for cosmetic safety (2015 edition), and the results were as follows

Shown in table 4.

As can be seen from the entries in Table 3, the samples of examples 1-5 all met the standards in the 41 glucocorticoid, sex hormone 7 and antibiotic 7 tests.

3. The samples of examples 1 to 5 and comparative examples 1 to 4 were sent to a test center and the anti-mite effect was tested. The test results are shown in the following 5.

The experimental basis is as follows: NY/T1151.1-2006 pesticide laboratory efficacy test method and evaluation second part for pesticide registration hygiene: mite killing and repelling agent, GB/T24253-

Test insects: dust mite, male and female adults

The experimental conditions are as follows: temperature: 25 ℃ plus or minus 2 ℃ and relative humidity of 75 percent plus or minus 5 percent

TABLE 5 anti-mite effect recording tables for examples 1 to 5 and comparative examples 1 to 4

	Example 1	Example 2	Example 3	Example 4	Example 5
						Mite-killing rate	99.56％	99.12％	99.32％	98.87％	98.56％
	Comparative example 1	Comparative example 2	Comparative example 3	Comparative example 4
						Mite-killing rate	96.45％	96.89％	97.23％	97.16％

As can be seen from the records in Table 5, the mite removing rate of the examples is better than that of the comparative examples, and the mite removing effect of the examples is the best. The components of the examples are synergistically effective to inhibit the growth of mites.

4. Acne removal efficacy test

The 450 acne volunteers were divided into 9 groups of 50 individuals, and the acne removing rate was measured after two weeks and eight weeks, respectively, by applying the acne removing gel of examples 1 to 5 and comparative examples 1 to 4, respectively, after cleansing the face and directly applying it in the morning and evening. The removal rate is calculated by the disappearance rate of the number of the whelks, namely the number of the reduced whelks/the total number of the whelks before use. The test results are shown in table 6 below, and the results of each example and comparative example are the average of the group of 50 volunteers.

Table 6 recording table of acne removing effect of examples 1 to 5 and comparative examples 1 to 4

As can be seen from the records in table 6, the acne removing effects of the examples are all better than those of the comparative examples, and particularly, the best effect was obtained in example 1. The skin conditioner of comparative example 1, which includes only the triple-pepper composition, is much less effective than example 1, and illustrates that the skin conditioners, melaleuca alternifolia water, potassium azeloyl diglycolate, gentian root extract, quaternary ammonium salt-73, purslane extract composition, melaleuca alternifolia oil, and citrus junos fruit oil, can greatly improve the anti-acne effect on the basis of the triple-pepper composition. Compared with the example 1, the comparative example 3 has less melaleuca alternifolia water and melaleuca alternifolia oil, and the effect is improved compared with the comparative example 1, but the comparative example 1 has a great difference, which shows that the melaleuca alternifolia water and the melaleuca alternifolia oil also play a key role in the whole formula; similarly, the formula of comparative example 4 has less humectant, and the acne removing effect is much worse than that of the examples, which shows that the components in the examples are properly combined, and the components take effect synergistically, but are absent, so that the acne removing effect is very good.

The above embodiments are only preferred embodiments of the present invention, and the protection scope of the present invention is not limited thereby, and any insubstantial changes and substitutions made by those skilled in the art based on the present invention are within the protection scope of the present invention.

Claims (10)

1. The acne-removing gel is characterized by being prepared from the following components in parts by weight: 60-70 parts of water, 5-10 parts of three-pepper composition, 4-8 parts of melaleuca alternifolia leaf water, 0.5-3 parts of potassium azeloyl diglycoate, 0.5-2 parts of radix gentianae extract, 0.5-2 parts of quaternary ammonium salt-730.5-3 parts, 0.5-2 parts of purslane extract composition, 0.05-1 part of melaleuca alternifolia leaf oil, 0.01-1 part of citrus junos fruit oil, 10-20 parts of humectant, 0.5-2 parts of solubilizer, 0.3-1.5 parts of thickener, 0.3-1.5 parts of antioxidant, 0.3-1.5 parts of pH regulator and 0.001-0.5 part of colorant.

2. The acne-removing gel of claim 1, wherein the three-pepper composition is composed of zanthoxylum bungeanum maxim extract, sophora flavescens ait root extract, capsicum frutescens extract, kava root extract, p-hydroxyacetophenone, 1, 2-hexanediol, and butylene glycol.

3. The anti-acne gel of claim 1, wherein the purslane extraction composition consists of water, butylene glycol, and a purslane extract.

4. The acne removal gel of claim 1, wherein the moisturizing agent is comprised of butylene glycol, glycerin, erythritol, sodium hyaluronate, and 1, 2-hexanediol.

5. The anti-acne gel of claim 1, wherein the solubilizing agent is PEG-40 hydrogenated castor oil; the thickening agent is carbomer and polyacrylate cross-linked polymer-6; the antioxidant is p-hydroxyacetophenone; the pH regulator is arginine.

6. The anti-acne gel of claim 1, wherein the colorant has color numbers CI 74260 and CI 42090.

7. The acne removal gel according to claim 2, which is prepared from the following components in parts by weight: 60-70 parts of water, 5-10 parts of a sanjiao composition, 4-8 parts of melaleuca alternifolia leaf water, 0.5-3 parts of potassium azelaidate, 0.5-2 parts of radix gentianae extract, 0.5-2 parts of a quaternary ammonium salt-730.5-3 parts, 0.5-2 parts of a purslane extraction composition, 0.05-1 part of melaleuca alternifolia leaf oil, 0.01-1 part of orange fruit oil, 7-10 parts of butanediol, 3-6 parts of glycerol, 0.5-2 parts of erythritol, 0.05-1 part of sodium hyaluronate, 0.1-1 part of 1, 2-hexanediol, 0.5-2 parts of PEG-40 hydrogenated castor oil, 0.1-1 part of carbomer, and 60.1-1 part of a polyacrylate cross-linked polymer, 0.3-1.5 parts of p-hydroxyacetophenone, 0.3-1.5 parts of arginine, 0.1-0.1 part of CI 742600.0001 and 0.1 part of CI 420900.00001.

8. The acne removal gel of claim 7, prepared from the following components in parts by weight: 64.36 parts of water, 7 parts of a sanjiao composition, 6 parts of melaleuca alternifolia leaf water, 1.5 parts of potassium nonanedioyl diglycoate, 1 part of radix gentianae extract, 731 parts of quaternary ammonium salt, 1 part of a purslane extraction composition, 0.12 part of melaleuca alternifolia leaf oil, 0.03 part of orange fruit oil, 9 parts of butanediol, 4 parts of glycerol, 1.5 parts of erythritol, 0.09 part of sodium hyaluronate, 0.5 part of 1, 2-hexanediol, 1.2 parts of PEG-40 hydrogenated castor oil, 0.5 part of carbomer, 60.25 parts of polyacrylate cross-linked polymer, 0.5 part of p-hydroxyacetophenone, 0.45 part of arginine, CI 742600.00032 parts and CI 420900.00002 parts.

9. The preparation method of the acne removing gel is characterized by comprising the following steps:

preheating: heating the mixing pot to 80-85 ℃;

a primary material mixing step: adding water, humectant, thickener and antioxidant into the mixing pot, heating to 80-85 deg.C, stirring and homogenizing for 2-5min until all raw materials are completely dissolved, maintaining the temperature for 20-35min, and cooling to obtain a first mixture;

a secondary material mixing step: cooling the first mixture to 55-65 ℃, adding a pH regulator in a formula amount, and uniformly stirring to obtain a second mixture;

and a third mixing step: mixing the solubilizer, the melaleuca alternifolia leaf oil and the orange fruit oil according to the formula ratio, and uniformly dispersing to obtain a third mixture;

and a fourth material mixing step: cooling the second mixture to 40-50 ℃, adding a formula amount of three-pepper composition, melaleuca alternifolia leaf water, potassium azeloyl diglycolate, radix gentianae extract, quaternary ammonium salt-73, purslane extract composition and the third mixture, and uniformly stirring to obtain a fourth mixture;

color matching: gradually adding the colorant with the formula amount into the fourth mixture, and uniformly stirring;

cooling and discharging: sampling, inspecting, cooling after being qualified, filtering and discharging.

10. The method for preparing the gel for removing acne according to claim 9, wherein the cooling operation involved in the preparation process is vacuum cooling.

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