CN112675095A

CN112675095A - Mite-removing, anti-allergy and whitening functional composite composition and preparation method thereof

Info

Publication number: CN112675095A
Application number: CN202110090290.3A
Authority: CN
Inventors: 蔡建平; 吴倩; 刘�英
Original assignee: Shanghai Jiaxin Biotechnology Co ltd
Current assignee: Shanghai Jiaxin Biotechnology Co ltd
Priority date: 2021-01-22
Filing date: 2021-01-22
Publication date: 2021-04-20

Abstract

The application relates to the field of skin care products, and particularly discloses a mite-removing, anti-allergy and whitening efficacy composite composition and a preparation method thereof; the composite composition is prepared from the following raw materials in parts by weight: chinese torreya extract, geranium extract, cinnamon extract, rosemary extract, zanthoxylum leaf extract, lemon eucalyptus leaf extract, mint extract, antibacterial composition, osmotic composition, soothing composition, fragrant composition and water; the preparation method comprises the following steps: weighing Chinese torreya extract, pelargonium graveolens extract and cinnamon extract, and mixing to obtain a primary mixture; weighing rosemary extract, pepper leaf extract, lemon eucalyptus leaf extract, mint extract and the primary mixture, and mixing to obtain a mixture; weighing antibacterial composition, osmotic composition, soothing composition, and fragrance composition, mixing with the mixture to obtain composite composition product; after the composite composition is applied to a skin care product, the skin care product has three effects of removing mites, resisting allergy, whitening and the like.

Description

Mite-removing, anti-allergy and whitening functional composite composition and preparation method thereof

Technical Field

The application relates to the field of skin care products, in particular to a composite composition with effects of removing mites, resisting allergy and whitening skin and a preparation method thereof.

Background

When people sleep at night, the face often directly contacts with a bed sheet, a quilt cover and a pillow, and mites on the bed sheet, the quilt cover and the pillow are easily attached to the surface of the skin, so that bacterial infection of the skin is easily caused, skin pores become large, skin metabolism is affected, skin metabolism disorder is caused, blackheads and the like appear, and therefore, the skin care product with the mite removing and whitening effects is deeply valued by people.

However, the mite removing performance of the skin care product is mainly to add active ingredients with mite removing effect in the skin care product, but for sensitive skin, the mite removing active ingredients are easy to generate irritant influence on the sensitive skin.

Therefore, no skin care product has three effects of removing mites, resisting allergy, whitening and the like.

Disclosure of Invention

In order to enable the skin care product to have three effects of removing mites, resisting allergy, whitening and the like, the application provides a mite-removing, anti-allergy and whitening effect composite composition and a preparation method thereof.

In a first aspect, the application provides a mite-removing, anti-allergy and whitening efficacy composite composition, which adopts the following technical scheme: the composite composition with the effects of removing mites, resisting allergy and whitening skin is prepared from the following raw materials in parts by weight: 5-10 parts of a torreya grandis extract, 6-12 parts of a pelargonium graveolens extract, 4-8 parts of a cinnamon extract, 4-6 parts of a rosemary extract, 5-8 parts of a pepper leaf extract, 3-7 parts of a lemon eucalyptus leaf extract, 3-6 parts of a mint extract, 8-15 parts of an antibacterial composition, 5-10 parts of a penetrating composition, 4-8 parts of a soothing composition, 3-6 parts of a fragrant composition and 10-15 parts of water.

By adopting the technical scheme, the Chinese torreya extracting solution, the pelargonium roseum extracting solution and the cinnamon extracting solution are matched, so that the composite composition has good mite removing performance; the rosemary extract, the pepper leaf extract and the Chinese torreya extract are matched, so that the composite composition has a good whitening effect; the combination of the soothing composition and the lemon eucalyptus leaf extract can effectively relieve the irritation of the effective components in the antibacterial composition, the torreya grandis, the cinnamon and the pelargonium graveolens to the skin, so that the sensitive skin can be normally used; the prepared composite composition has the effects of removing mites, resisting allergy, whitening and the like.

Because the mites mainly live on the face by virtue of the grease on the face, the rosemary extract, the pepper leaf extract and the lemon eucalyptus leaf extract are matched, the metabolism of the skin can be enhanced, the dead skin metabolism speed of the skin is increased, the grease blocked in pores can be promoted to be discharged out of the pores, and the mite removing effect is achieved; the mint extract and the lemon eucalyptus leaf extract are matched, so that the shrinkage of pores is accelerated, mites and bacteria on the surface of skin are prevented from entering the pores again, the pores become small, the amount of secreted oil is reduced, and the effect of removing the mites is achieved; the active ingredients in the composite composition can quickly permeate into pores to play a role by matching with the good permeability of the permeable composition, so that the composite composition has a good mite removing effect.

Preferably, the antibacterial composition is prepared from the following raw materials in parts by weight: 4-10 parts of folium artemisiae argyi extract, 3-8 parts of eucalyptus globulus leaf extract, 3-6 parts of perilla leaf extract, 2-7 parts of herba moslae extract, 2-4 parts of radix sophorae flavescentis extract and 2-5 parts of sweet wormwood herb extract.

By adopting the technical scheme, the folium artemisiae argyi extract, the perilla leaf extract and the elsholtzia extract are matched, so that the composite composition has a good bacteriostatic action on escherichia coli and staphylococcus aureus, and therefore, mites are prevented from carrying bacteria to enter pores and affecting oil secretion on the surface of skin, and a good environment is prevented from being created for growth of the mites; the folium artemisiae argyi extract, the eucalyptus globulus labill leaf extract and the eucalyptus citriodora leaf extract are matched, so that cell proliferation can be promoted, the generation of new cells is accelerated, the skin metabolism efficiency is improved, and therefore the situation that pores are blocked by grease and beneficial to the growth of mites is avoided; the radix sophorae flavescentis extract, the perilla leaf extract and the sweet wormwood herb extract are matched, so that the antibacterial agent has good antibacterial performance and can promote the formation of collagen.

Preferably, the osmotic composition consists of melaleuca alternifolia extract and azone in a weight ratio of 2: 3.

By adopting the technical scheme, the intergrown leaf extracting solution is matched with azone, and the higher stratum corneum penetration effect of the azone is matched with the better corium layer penetration effect of the intergrown leaf extracting solution, so that the effective components in the composite composition can quickly penetrate into the corium layer and act on the corium layer, the metabolism of the skin is promoted, and a large amount of grease secreted on the surface of the skin is avoided, so that good survival conditions are provided for the growth of mites; and the azone has good lipophilic osmosis, so that the azone carries the intergrowth leaf extracting solution to promote effective components in the composite composition to permeate into pores, oil, mites, bacteria, microorganisms and the like in the pores are cleaned, and the oil blocked in the pores can be quickly discharged by matching with the metabolism of skin, so that the composite composition has good mite removing effect, whitening effect and anti-allergy effect.

Preferably, the soothing composition consists of an extracting solution of hemerocallis fulva and an extracting solution of balsam fir in a weight ratio of 1 (1-3).

By adopting the technical scheme, the hemerocallis fulva extracting solution and the balsam fir extracting solution are matched, so that the irritation of active ingredients in the torreya grandis, the cinnamon extracting solution and the perilla frutescens to skin can be effectively relieved, and the composite composition has a good anti-allergy effect by matching with the folium artemisiae argyi extracting solution and the eucalyptus globulus leaf extracting solution.

Preferably, the flavor composition consists of citronella extract and typha extract in a weight ratio of 1 (1-2).

By adopting the technical scheme, the citronella extract and the typha extract are matched to effectively neutralize the smell of cinnamon extract, perilla extract and the like; the compound composition can effectively inhibit the odor in the compound composition by matching with the extract of the melaleuca alternifolia and the extract of the eucalyptus citriodora leaves, so that the finished compound composition has mild odor and is not irritant.

Preferably, the mite-removing, anti-allergic and whitening efficacy composite composition further comprises the following raw materials in parts by weight: 3-6 parts of an oil absorbing composition; the oil absorption composition is prepared from the following raw materials in parts by weight: 1-3 parts of chitosan solution, 4-6 parts of mesoporous silica, 1-3 parts of polyvinyl alcohol and 3-8 parts of water.

By adopting the technical scheme, the chitosan solution, the polyvinyl alcohol and the mesoporous silica are matched, and the grease secreted on the surface of the skin can be absorbed for a long time, so that the mites on the surface of the skin are prevented from contacting with the grease on the surface of the skin, and the grease on the surface of the skin can be promoted to enter a mesoporous silica pore structure by matching with the extract of the melaleuca alternifolia, so that the aim of inhibiting the growth of the mites is fulfilled.

The chitosan is positioned in the pores of the mesoporous silica by utilizing the good adhesive property of the polyvinyl alcohol after being dissolved in water, the chitosan molecules contain hydroxyl, acetamido and amino, so that the chitosan has good adsorption effect, the amino of the chitosan enables the chitosan to become positive ions, and the fatty acid is negatively charged, due to the electrostatic effect, the grease enters the pore structure of the mesoporous silica, the grease is stored by the pore structure of the mesoporous silica, the grease is prevented from being blocked at the pore inlets of the mesoporous silica by matching with the lubricating effect of the polyvinyl alcohol, the mesoporous silica has larger and deeper pores, the grease secreted from the surface of the skin can be adsorbed for a long time, the grease is prevented from being attached to the surface of the skin to provide nutrient substances for the growth of mites, the mites cannot enter the pores of the mesoporous silica, and the mesoporous silica can be separated from the surface of the skin when makeup is removed, and thus does not affect the skin.

Preferably, the oil-absorbing composition is prepared by the following method:

weighing polyvinyl alcohol, mixing with water, adding mesoporous silica, stirring at the rotation speed of 500-750r/min for 3-7min, adding the chitosan solution within 30-60s, performing ultrasonic dispersion for 3-6min under the condition of 20-40 kHz while adding the chitosan solution, and drying at room temperature to obtain the oil-absorbing composition.

By adopting the technical scheme, firstly, polyvinyl alcohol and water are mixed, the polyvinyl alcohol is dissolved in the water, then the mesoporous silicon dioxide is added, the stirring speed and the stirring time are limited, the dissolution of the polyvinyl alcohol is ensured, and the polyvinyl alcohol is preliminarily attached to the surface of the mesoporous silicon dioxide; and then, adding a chitosan solution, performing ultrasonic dispersion, and limiting the adding speed of the chitosan solution to enable the chitosan solution to be uniformly dispersed in the pores of the mesoporous silica, so that grease secreted from the surface of the skin can enter the pores of the mesoporous silica.

In a second aspect, the application provides a preparation method of the mite-removing, anti-allergy and whitening efficacy composite composition, which adopts the following technical scheme:

a preparation method of the composite composition with the effects of removing mites, resisting allergy and whitening skin comprises the following steps:

s1, weighing the Chinese torreya extracting solution, the geranium extracting solution and the cinnamon extracting solution, and mixing to prepare a primary mixture;

s2, mixing the rosemary extract, the pepper leaf extract, the lemon eucalyptus leaf extract and the mint extract with the primary mixture prepared in the step S1 to prepare a mixture;

s3, weighing the antibacterial composition, the osmotic composition, the soothing composition and the fragrance composition, and mixing with the mixture prepared in the S2 to obtain a finished product of the composite composition.

By adopting the technical scheme, the raw materials are respectively mixed to prepare the finished composite composition, so that the composite composition is uniformly mixed, the production loss can be reduced, and the production efficiency is improved.

In summary, the present application has the following beneficial effects:

1. the torreya grandis extract, the pelargonium graveolens extract and the cinnamon extract are matched, so that the composite composition has good mite removing performance; the rosemary extract, the pepper leaf extract and the Chinese torreya extract are matched, so that the composite composition has a good whitening effect; the combination of the soothing composition and the lemon eucalyptus leaf extracting solution can effectively relieve the irritation of the effective components in the antibacterial composition, the torreya grandis, the cinnamon extracting solution and the pelargonium graveolens to the skin, so that the sensitive skin can be normally used; the prepared composite composition has the effects of removing mites, resisting allergy, whitening and the like.

2. Under the matching of the mixed leaf extracting solution and the azone, when the composite composition is contacted with the surface of the skin, the effective active ingredients in the composite composition penetrate through the horny layer and permeate into the corium layer, and when the sebaceous glands secrete grease, the grease enters the pore structure of the mesoporous silicon dioxide, so that the grease is prevented from being attached to the surface of the skin and being contacted with mites on the surface of the skin, the aim of inhibiting the growth of the mites is finally fulfilled, and the composite composition has a good mite removing effect.

3. The antibacterial composition has good antibacterial performance and can inhibit the growth of mites on the surface of the skin; the fragrance composition and the lemon eucalyptus leaf are matched to effectively neutralize the odor of substances such as cinnamon extract, perilla and the like, so that the compound composition is mild in taste and not irritating.

4. The torreya grandis extract, the rosemary extract, the pepper extract and the citronella extract are matched, melanin in skin is removed by inhibiting the secretion of melanin and promoting the discharge of melanin, and the skin moistening effect is matched, so that the skin surface is full and smooth, the proliferation of cuticle is promoted, and the composite composition has a good whitening effect.

Detailed Description

The present application will be described in further detail with reference to examples.

Preparation example of antibacterial composition

The folium artemisiae argyi extract in the following raw materials is purchased from Guangzhou ruilin biotechnology limited and has the content of 100 percent; the extractive solution of Eucalyptus globulus Labill is purchased from XN-071, model number of XN-071, Shantou, Shannuo chemical engineering science and technology company; the perilla leaf extract is purchased from gazania gabonensis biotechnology limited, Guangzhou, and has an effective substance content of 10%; herba Moslae extract is purchased from Xian Mingze Biotech limited; the radix Sophorae Flavescentis extract is purchased from Weishi Gem Biotech, Guangzhou, with a content of 98%; the herba Artemisiae Annuae extract is purchased from Guangzhou American Biotechnology limited company, and has a content of 98%.

Preparation example 1: the antibacterial composition is prepared by the following method:

weighing 6kg of folium Artemisiae Argyi extract, 5kg of Eucalyptus globulus Labill leaf extract, 4kg of folium Perillae extract, 5kg of herba Moslae extract, 3kg of radix Sophorae Flavescentis extract and 3kg of herba Artemisiae Annuae extract, mixing, and stirring at 500r/min for 4min to obtain the antibacterial composition.

Preparation example 2: the antibacterial composition is prepared by the following method:

weighing 4kg of folium Artemisiae Argyi extract, 3kg of Eucalyptus globulus Labill leaf extract, 3kg of folium Perillae extract, 2kg of herba Moslae extract, 2kg of radix Sophorae Flavescentis extract and 2kg of herba Artemisiae Annuae extract, mixing, and stirring at 500r/min for 4min to obtain the antibacterial composition.

Preparation example 3: the antibacterial composition is prepared by the following method:

weighing 10kg of folium Artemisiae Argyi extract, 8kg of Eucalyptus globulus Labill leaf extract, 6kg of folium Perillae extract, 7kg of herba Moslae extract, 4kg of radix Sophorae Flavescentis extract and 5kg of herba Artemisiae Annuae extract, mixing, and stirring at 500r/min for 4min to obtain the antibacterial composition.

Preparation of oil-absorbing composition chitosan of the following raw materials was purchased from magnificent university of Sichuan, Inc., and the content of active substance was 99%; polyvinyl alcohol is purchased from Henan Ding Xiang chemical products Co., Ltd, model 2699; other raw materials and equipment are all sold in the market.

Preparation example 4: the oil absorption composition is prepared by the following method:

weighing 5g of chitosan, placing the chitosan in 100g of acetic acid with the mass fraction of 2%, and stirring for 8min at the rotating speed of 500r/min to prepare a chitosan solution;

weighing 2kg of polyvinyl alcohol and 5kg of water, mixing, adding 5kg of mesoporous silica, stirring for 5min at the rotating speed of 650r/min, adding 2kg of the prepared chitosan solution within 45s, performing ultrasonic dispersion for 5min at 30kHz while adding the chitosan solution, and drying for 25min at room temperature to obtain the oil-absorbing composition.

Preparation example 5: the oil absorption composition is prepared by the following method:

weighing 1kg of polyvinyl alcohol and 3kg of water, mixing, adding 4kg of mesoporous silica, stirring for 3min at the rotating speed of 500r/min, adding 1kg of the chitosan solution prepared in the first step within 30s, performing ultrasonic dispersion for 3min under the condition of 20kHz while adding the chitosan solution, and drying for 25min at room temperature to obtain the oil absorption composition.

Preparation example 6: the oil absorption composition is prepared by the following method:

weighing 3kg of polyvinyl alcohol and 8kg of water, mixing, adding 6kg of mesoporous silica, stirring for 7min at the rotating speed of 750r/min, adding 3kg of the prepared chitosan solution within 60s, performing ultrasonic dispersion for 6min at 40kHz while adding the chitosan solution, and drying for 25min at room temperature to obtain the oil-absorbing composition.

Examples

The torreya grandis extract in the following raw materials is purchased from Shaanxi Sinuote biotechnology limited company, and the content of active substances is 10%; the cinnamon extracting solution is purchased from American-exemplary Biotech limited of Guangzhou, and the content of active substances is 10 percent; the pelargonium roseum extract is purchased from pelargonium roseum extract produced by Hongtai chemical industry limited company in Guangzhou, the content is not less than 100%; the rosemary extract is purchased from Hongxin chemical industry limited company in Guangzhou, and the content is not less than 100 percent; the extraction solution of the pepper leaves is purchased from Simansuote biotechnology limited; the lemon eucalyptus leaf extract is purchased from Jining Tano chemical company, Inc.; the herba Menthae extract is purchased from Chengtong Biotechnology GmbH of Guangzhou; the melaleuca alternifolia extract is purchased from Shanghai Jingchun Biotech limited; azone was purchased from american biotechnology limited, guangzhou; hemerocallis extract was purchased from Walterlesh Biotech, Lanzhou; fir extract was purchased from Guanao Biotech limited, Hubei; the citronella extract is purchased from Junda natural perfume oil factory in Jishui county; typha angustifolia extract was purchased from Ningxia vanilla Biotechnology Inc.; other raw materials and equipment are all sold in the market.

Example 1: a preparation method of a composite composition with mite-removing, anti-allergy and whitening effects comprises the following steps:

s1, weighing 8kg of Chinese torreya extract, 10kg of geranium extract and 6kg of cinnamon extract, mixing, and stirring at the rotating speed of 500r/min for 10min to obtain a primary mixture;

s2, weighing 5kg of rosemary extract, 6.5kg of pepper leaf extract, 5.5kg of lemon eucalyptus leaf extract, 4.8kg of mint extract and the primary mixture prepared in the S1, mixing, and stirring at the rotating speed of 550r/min for 8min to prepare a mixture;

s3, weighing 12.6kg of the antibacterial composition prepared in the preparation example 1, 8.5kg of the penetrating composition, 6.6kg of the soothing composition, 4.8kg of the fragrance composition and the mixture prepared in the S2, mixing, and stirring at the rotating speed of 500r/min for 10min to prepare a finished composite composition; the osmotic composition consists of the extract of melaleuca alternifolia and azone in a weight ratio of 2: 3; the soothing composition consists of hemerocallis fulva extract and balsam fir extract in a weight ratio of 1: 2; the flavor composition comprises citronella extract and typha extract in a weight ratio of 1: 1.4.

Example 2: a preparation method of a composite composition with mite-removing, anti-allergy and whitening effects comprises the following steps:

s1, weighing 5kg of Chinese torreya extract, 6kg of geranium extract and 4kg of cinnamon extract, mixing, and stirring at the rotating speed of 500r/min for 10min to obtain a primary mixture;

s2, weighing 4kg of rosemary extract, 5kg of pepper leaf extract, 3kg of lemon eucalyptus leaf extract, 3kg of mint extract and the primary mixture prepared in the step S1, mixing, and stirring at the rotating speed of 550r/min for 8min to prepare a mixture;

s3, weighing 8kg of the antibacterial composition prepared in the preparation example 2, 4kg of the penetrating composition, 4kg of the relieving composition, 3kg of the fragrance composition and the mixture prepared in the S2, mixing, and stirring at the rotating speed of 500r/min for 10min to obtain a finished composite composition; the osmotic composition consists of the extract of melaleuca alternifolia and azone in a weight ratio of 2: 3; the soothing composition consists of hemerocallis fulva extract and balsam fir extract in a weight ratio of 1: 1; the flavor composition comprises citronella extract and typha extract in a weight ratio of 1:1.

Example 3: a preparation method of a composite composition with mite-removing, anti-allergy and whitening effects comprises the following steps:

s1, weighing 10kg of Chinese torreya extract, 12kg of geranium extract and 8kg of cinnamon extract, mixing, and stirring at the rotating speed of 500r/min for 10min to obtain a primary mixture;

s2, weighing 6kg of rosemary extract, 8kg of pepper leaf extract, 7kg of lemon eucalyptus leaf extract, 6kg of mint extract and the primary mixture prepared in the step S1, mixing, and stirring at the rotating speed of 550r/min for 8min to prepare a mixture;

s3, weighing 15kg of the antibacterial composition prepared in the preparation example 3, 10kg of the osmotic composition, 8kg of the soothing composition, 6kg of the fragrance composition and the mixture prepared in the S2, mixing, and stirring at the rotating speed of 500r/min for 10min to obtain a finished composite composition; the osmotic composition consists of the extract of melaleuca alternifolia and azone in a weight ratio of 2: 3; the soothing composition consists of hemerocallis fulva extract and balsam fir extract in a weight ratio of 1: 3; the flavor composition comprises citronella extract and typha extract in a weight ratio of 1: 2.

Example 4: the present embodiment is different from embodiment 1 in that:

s3, weighing 12.6kg of the antibacterial composition prepared in preparation example 1, 8.5kg of the penetrating composition, 6.6kg of the soothing composition, 4.8kg of the fragrance composition and the mixture prepared in S2, mixing, stirring at the rotating speed of 500r/min for 10min, adding 4.8kg of the oil-absorbing composition prepared in preparation example 4, and continuing to stir for 3min to prepare a finished composite composition.

Example 5: the present embodiment is different from embodiment 1 in that:

s3, weighing 12.6kg of the antibacterial composition prepared in preparation example 1, 8.5kg of the penetrating composition, 6.6kg of the soothing composition, 4.8kg of the fragrance composition and the mixture prepared in S2, mixing, stirring at the rotating speed of 500r/min for 10min, then adding 3kg of the oil-absorbing composition prepared in preparation example 5, and continuing stirring for 3min to prepare a finished composite composition.

Example 6: the present embodiment is different from embodiment 1 in that:

s3, weighing 12.6kg of the antibacterial composition prepared in preparation example 1, 8.5kg of the penetrating composition, 6.6kg of the soothing composition, 4.8kg of the fragrance composition and the mixture prepared in S2, mixing, stirring at the rotating speed of 500r/min for 10min, then adding 6kg of the oil-absorbing composition prepared in preparation example 6, and continuing stirring for 3min to prepare a finished composite composition.

Example 7: the present embodiment is different from embodiment 1 in that:

the osmotic composition is the extractive solution of Melaleuca alternifolia; the soothing composition is an extractive solution of hemerocallis fulva; the flavor composition is herba Cymbopogonis Citrari extractive solution.

Example 8: the present embodiment is different from embodiment 1 in that:

the osmotic composition is azone; the soothing composition is balsam fir extractive solution; the flavor composition is herba Typhae extractive solution.

Note: osmotic compositions include, but are not limited to, melaleuca alternifolia extract and azone; the soothing extractive solution includes, but is not limited to, hemerocallis extract, balsam fir extract; the flavor composition includes, but is not limited to, citronella extract and typha extract.

Comparative example

Comparative example 1: this comparative example differs from example 1 in that: the Chinese torreya extracting solution is replaced by the Chinese cinnamon extracting solution with the same mass in the raw materials.

Comparative example 2: this comparative example differs from example 1 in that: the cinnamon extracting solution is replaced by the pelargonium graveolens extracting solution with the same mass in the raw materials.

Comparative example 3: this comparative example differs from example 1 in that: the raw materials are replaced by rosemary extract with the same mass for pepper extract.

Comparative example 4: this comparative example differs from example 1 in that: the raw materials are replaced by the rosemary extract with the same mass as the lemon eucalyptus leaf extract.

Comparative example 5: this comparative example differs from example 1 in that: the raw materials are prepared by replacing the peppermint extract with the lemon eucalyptus extract with the same mass.

Comparative example 6: this comparative example differs from example 1 in that: the raw materials are prepared by replacing folium artemisiae argyi extract with herba elsholtziae extract with the same mass.

Comparative example 7: this comparative example differs from example 1 in that: the raw materials are replaced by the same quality of radix sophorae flavescentis extract liquid.

Comparative example 8: this comparative example differs from example 1 in that: the raw materials are substituted by azone with the same mass for the extract of the melaleuca alternifolia.

Comparative example 9: this comparative example differs from example 1 in that: the raw materials are replaced by the equal mass of day lily extract liquid.

Comparative example 10: this comparative example differs from example 1 in that: the raw materials are replaced by citronella extract with the same mass.

Comparative example 11: this embodiment is different from embodiment 4 in that: the oil-absorbing composition is prepared from raw materials without adding polyvinyl alcohol.

Comparative example 12: this embodiment is different from embodiment 4 in that: the oil absorption combined raw material is not added with mesoporous silicon dioxide.

Comparative example 13: this embodiment is different from embodiment 4 in that:

weighing 2kg of polyvinyl alcohol, mixing with 5kg of water, adding 5kg of mesoporous silica, adding 2kg of the chitosan solution prepared in the step I within 45s, ultrasonically dispersing for 5min at 30kHz while adding the chitosan solution, and drying for 25min at room temperature to prepare the oil absorption composition.

Comparative example 14: this embodiment is different from embodiment 4 in that:

weighing 2kg of polyvinyl alcohol and 5kg of water, mixing, adding 5kg of mesoporous silica, stirring at the rotating speed of 650r/min for 5min, then adding 2kg of the chitosan solution prepared by the first step at one time, ultrasonically dispersing for 5min under the condition of 30kHz while adding the chitosan solution, and drying for 25min at room temperature to prepare the oil absorption composition.

Performance test

1. Detection of mite-inhibiting and bacteriostatic performance of composition

The preparation methods of the examples 1-8 and the comparative examples 1-14 are respectively adopted to prepare the composite composition, 4g of the composite composition, 6g of glycerol and 0.03g of hyaluronic acid are weighed and placed in 100g of water, the temperature is raised to 60 ℃, the stirring is carried out for 5min at the rotating speed of 450r/min, and the finished product essence water is prepared after the cooling to the room temperature.

As can be seen from the mechanism of formation of Demodex mites, two kinds of bacteria were present in the skin of the skin lesions, with 94.3% of Staphylococcus epidermidis and 1.1% of Staphylococcus aureus, and therefore, the in vitro mite-inhibiting effects of examples 1 to 8 and comparative examples 1 to 14 were reflected and the mite-inhibiting time was recorded by using the following method as a substitute test.

Selecting a strain: staphylococcus aureus ATCC100817 (identified as bacteria a); staphylococcus epidermidis ATCC12228 (noted as bacterium B);

preparing a culture medium: beef extract medium (staphylococcus aureus and staphylococcus epidermidis): mixing 3g of beef extract, 10g of peptone, 15g of NaCl, 15g of agar, 1000mL of water and pH7.0-7.2, shaking up, heating and stirring on the surface of an electric heating furnace until the culture medium solution boils slightly, keeping the state for 5-10min, placing the mixture into a sterilization pot, sterilizing the mixture at 121 ℃ for 20min, and taking out the mixture for later use when the mixture is cooled to 60 ℃;

activating strains: the strain is purchased as freeze-dried powder which is filled in an ampoule tube, the top of the ampoule tube is subjected to aseptic processing, about 0.1mL of liquid is dripped into the ampoule tube by a liquid transfer gun for culture, the liquid is shaken uniformly, then a strain inoculating ring is used for picking the strain and inoculating the strain onto a corresponding flat plate and a corresponding inclined plane for activation, and the strain is placed in a constant temperature incubator at 37 ℃ for culture for 24 hours;

preparation of bacterial suspension: taking a plurality of activated strains, and under the aseptic condition, selecting a ring of activated strains, putting the activated strains into 9mL of sterile water, shaking up, and preparing a bacterial suspension;

determination of bacteriostatic efficacy: shaking the culture medium uniformly, pouring the culture medium into flat plates, cooling and solidifying, dripping a certain proportion of bacterial suspension on the flat plates, uniformly coating the surfaces of the flat plates for 3 times by using a coating rod, rotating the flat plates for 60 degrees every time of coating, finally coating the bacterial suspension on the flat plates for a circle by using the coating rod, covering the flat plates, drying the flat plates for 5min at room temperature, lightly placing an oxford cup with the inner diameter of 6mm on the solidified culture medium by using tweezers, and uniformly placing three flat plates; sucking a sample by using a 1mL disposable needle, injecting the sample into an Oxford cup, adding about 400 microliters of sample (the samples are respectively the essence water prepared in examples 1-3 and comparative examples 1-8) into each cup, respectively culturing staphylococcus aureus and staphylococcus epidermidis in an incubator at 37 ℃ for 12 hours, measuring the diameter of a bacteriostatic ring by using a vernier caliper, selecting a bacteriostatic ring with uniform and complete aseptic growth for recording when measuring the bacteriostatic ring, and taking the measured diameter outside the bacteriostatic ring as a limit.

Observing that the inhibition zone does not extend any more is the inhibition time, thus reflecting the mite inhibition time.

2. Composition functionality detection

Searching 220 sensitive skin volunteers, averagely dividing into 22 groups, using finished product essence water by 10 persons in each group and 22 groups of volunteers respectively, and after using for 30 days and 60 days, scoring the finished product essence water; the scoring criteria were as follows: 7-10 minutes, the essence water has no stimulation, whitening effect, fine line fading effect and oil absorption effect; 4-7 minutes, slight stimulation of essence water, poor whitening effect, fine line fading effect and poor oil absorption; 0-4 minutes, and the effect of whitening, fading fine lines and absorbing oil due to the stimulation of essence water is avoided.

TABLE 1 composition Performance test Table

By combining examples 1-3 and examples 4-6 and table 1, it can be seen that the oil-absorbing composition is added to the raw materials of examples 4-6, compared to example 1, the diameters of the inhibition rings of bacteria a and B of example 4 are both larger than those of bacteria a and B of example 1, the inhibition times of bacteria a and B of example 4 are both larger than those of bacteria a and B of example 1, and the score of example 4 is higher than that of example 1; the oil absorption composition, the antibacterial composition, the Chinese torreya extract, the geranium extract and the like are matched, so that staphylococcus aureus and staphylococcus epidermidis can be effectively inhibited, a good mite inhibiting effect is achieved, and the anti-sensitivity and whitening effects are achieved.

By combining examples 1-3 and comparative examples 1-10 and table 1, it can be seen that, in the raw material of comparative example 1, the Chinese torreya extract is replaced by the cinnamon extract with the same mass, in the raw material of comparative example 2, the geranium extract with the same mass is replaced by the cinnamon extract, compared with example 1, the diameters of the inhibition rings of comparative examples 1, 2, A and B are smaller than those of examples 1, the inhibition times of comparative examples 1, 2, A and B are smaller than those of examples 1, A and B, and the scores of comparative examples 1 and 2 are lower than those of example 1; the matching of the Chinese torreya extracting solution, the pelargonium roseum extracting solution and the cinnamon extracting solution is proved to ensure that the composite composition has good mite removing performance; and has skin whitening and anti-allergy effects.

Compared with the example 1, the proportion of the rosemary extract, the pricklyash peel leaf extract and the Chinese torreya extract in the comparative example 3 is obviously lower than that in the example 1, so that the rosemary extract, the pricklyash peel leaf extract and the Chinese torreya extract are matched, and the composite composition has a good whitening effect.

In the comparative example 4, the rosemary extract with the same mass is used for replacing the lemon eucalyptus leaf extract, and in the comparative example 5, the lemon eucalyptus leaf extract with the same mass is used for replacing the mint extract; compared with example 1, the diameters of the inhibition rings of comparative examples 4, 5, A and B are smaller than those of example 1, the inhibition times of comparative examples 4, 5, A and B are smaller than those of example 1, and the fractions of comparative examples 4 and 5 are lower than that of example 1; the rosemary extract, the pepper leaf extract and the lemon eucalyptus leaf extract are matched, so that the metabolism of the skin can be enhanced, the dead skin metabolism speed of the skin is increased, and the grease blocked in pores can be promoted to be discharged out of the pores, so that the mite removing effect is achieved; the mint extract and the lemon eucalyptus leaf extract are matched, so that the shrinkage of pores is accelerated, mites and bacteria on the surface of skin are prevented from entering the pores again, the pores become small, the amount of secreted oil is reduced, and the effect of removing the mites is achieved.

Compared with the example 1, the diameters of the bacteriostatic rings of the comparative examples 6, 7, A and B are smaller than those of the bacterium A and B in the example 1, the bacteriostatic time of the comparative examples 6, 7, A and B is smaller than that of the bacterium A and B in the example 1, and the fractions of the comparative examples 6 and 7 are lower than that of the example 1; the blending of the aromatherapy extract, the artemisia apiacea extract, the artemisia argyi extract and the sophora flavescens extract is proved to ensure that the composition has good antibacterial performance, so that the composition has good mite removing performance.

Compared with the example 1, the diameters of the inhibition rings of the bacterium A and the bacterium B of the comparative example 8 are both smaller than those of the bacterium A and the bacterium B of the example 1, the inhibition times of the bacterium A and the bacterium B of the comparative example 8 are both smaller than those of the bacterium A and the bacterium B of the example 1, and the fraction of the comparative example 8 is lower than that of the example 1; the azone and the melaleuca alternifolia have good permeability, so that the permeability of the effective active ingredients in the composition is improved.

Compared with the example 1, compared with the raw material of the comparative example 9, the orange daylily extract and the citronella extract of the same mass are respectively used for replacing the balsam fir extract and the citronella extract of the comparative example 10, the diameters of the bacteriostatic rings of the comparative examples 9, 10, A and B are respectively smaller than those of the bacteria A and B of the example 1, the bacteriostatic time of the comparative examples 9, 10, A and B is respectively smaller than that of the bacteria A and B of the example 1, and the scores of the comparative examples 9 and 10 are respectively lower than the score of the example 1; the hemerocallis fulva extracting solution is matched with the balsam fir extracting solution, so that the composition has good calming and soothing effects, and has a good anti-allergy effect; the citronella extract and the typha extract are matched to effectively cover the pungent smell in the raw materials of the composition, so that the composition has good sensory performance.

As can be seen by combining examples 4 to 6 and comparative examples 11 to 14 and table 1, the raw material of the oil-absorbing composition in comparative example 11 is not added with polyvinyl alcohol, the raw material of the oil-absorbing composition in comparative example 12 is not added with mesoporous silica, compared with example 4, the diameters of the inhibition rings of comparative examples 11, 12, a and B are smaller than those of example 1, the inhibition times of comparative examples 11, 12, a and B are smaller than those of example 1, and the fractions of comparative examples 11 and 12 are lower than those of example 1; the chitosan solution, the polyvinyl alcohol and the mesoporous silicon dioxide are matched, and the grease secreted on the surface of the skin can be absorbed for a long time, so that the mites on the surface of the skin are prevented from contacting the grease on the surface of the skin, the growth of the mites is cut off, and the effect of inhibiting the mites is achieved.

Comparative example 13 when preparing the oil absorbing composition, the chitosan solution was directly added without stirring after mixing the polyvinyl alcohol, water and mesoporous silica, compared to example 4, the diameters of the inhibition rings of comparative example 13, bacterium a and bacterium B were both smaller than those of example 1, the inhibition times of comparative example 13, bacterium a and bacterium B were both smaller than those of example 1, and the fraction of comparative example 13 was lower than that of example 1; the mixing and stirring of the polyvinyl alcohol and the mesoporous silica can enable the polyvinyl alcohol to be initially attached to the surface of the mesoporous silica, and the good lubricating effect of the polyvinyl alcohol is utilized to facilitate grease to enter the pores of the mesoporous silica, so that the grease on the surface of the skin is adsorbed, and the growth of mites is cut off.

Comparative example 14 when the oil absorbing composition is prepared, the chitosan solution is added at one time, compared with example 4, the diameters of the inhibition rings of comparative example 14, namely bacterium a and bacterium B are smaller than those of example 1, namely bacterium a and bacterium B, the inhibition time of comparative example 14, namely bacterium a and bacterium B is smaller than that of example 1, and the score of comparative example 14 is smaller than that of example 1; the specification shows that the addition speed of the chitosan solution is limited, so that the chitosan solution can be uniformly dispersed in the pores of the mesoporous silica, and the oil can be conveniently adsorbed.

The present embodiment is only for explaining the present application, and it is not limited to the present application, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present application.

Claims

1. The mite-removing, anti-allergy and whitening functional composite composition is characterized by being prepared from the following raw materials in parts by weight: 5-10 parts of a torreya grandis extract, 6-12 parts of a pelargonium graveolens extract, 4-8 parts of a cinnamon extract, 4-6 parts of a rosemary extract, 5-8 parts of a pepper leaf extract, 3-7 parts of a lemon eucalyptus leaf extract, 3-6 parts of a mint extract, 8-15 parts of an antibacterial composition, 5-10 parts of a penetrating composition, 4-8 parts of a soothing composition, 3-6 parts of a fragrant composition and 10-15 parts of water.

2. The mite-removing, anti-allergy and whitening efficacy composite composition according to claim 1, which is characterized in that: the antibacterial composition is prepared from the following raw materials in parts by weight: 4-10 parts of folium artemisiae argyi extract, 3-8 parts of eucalyptus globulus leaf extract, 3-6 parts of perilla leaf extract, 2-7 parts of herba moslae extract, 2-4 parts of radix sophorae flavescentis extract and 2-5 parts of sweet wormwood herb extract.

3. The mite-removing, anti-allergy and whitening functional composite composition according to claim 1, wherein the penetrating composition consists of melaleuca alternifolia extract and azone in a weight ratio of 2: 3.

4. The mite-removing, anti-allergy and whitening functional composite composition as claimed in claim 1, wherein the soothing composition is composed of an extracting solution of hemerocallis fulva and an extracting solution of balsam fir in a weight ratio of 1 (1-3).

5. The mite-removing, anti-allergy and whitening functional composite composition as claimed in claim 1, is characterized in that the fragrance composition is composed of citronella extract and typha extract in a weight ratio of 1 (1-2).

6. The mite-removing, anti-allergy and whitening efficacy composite composition according to claim 1, which is characterized by further comprising the following raw materials in parts by weight: 3-6 parts of an oil absorbing composition; the oil absorption composition is prepared from the following raw materials in parts by weight: 1-3 parts of chitosan solution, 4-6 parts of mesoporous silica, 1-3 parts of polyvinyl alcohol and 3-8 parts of water.

7. The mite-removing, anti-allergy and whitening efficacy composite composition according to claim 6, characterized in that the oil-absorbing composition is prepared by the following method:

8. The preparation method of the mite-removing, anti-allergy and whitening efficacy composite composition as claimed in any one of claims 1 to 7, is characterized by comprising the following steps: