CN110420266B - Acne-removing and mite-removing agent with three kinds of pepper - Google Patents
Acne-removing and mite-removing agent with three kinds of pepper Download PDFInfo
- Publication number
- CN110420266B CN110420266B CN201910737287.9A CN201910737287A CN110420266B CN 110420266 B CN110420266 B CN 110420266B CN 201910737287 A CN201910737287 A CN 201910737287A CN 110420266 B CN110420266 B CN 110420266B
- Authority
- CN
- China
- Prior art keywords
- acne
- pepper
- mite
- plant powder
- capsicum frutescens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a three-pepper acne-removing and mite-removing agent, which mainly comprises pepper (ZANTHOXYLUM BUNGEANUM) fruit extract, CAPSICUM FRUTESCENS (CAPSICUM FRUTESCENS) fruit extract and kava (pepper methylstericum) root extract. The three-pepper acne-removing composition disclosed by the invention can reduce grease secretion, ensure that the cuticle is normally peeled off, has a good mite-removing effect and can effectively solve the problem of repeated attack of whelks.
Description
Technical Field
The invention relates to a product for removing acnes and mites, and in particular relates to a three-pepper acne-removing mite-removing agent.
Background
In 1841, human Demodex mites were first discovered by Berger in the human external auditory canal and were then presented to Paris' academy of sciences as confidential reports; in 1842, G Simon published a paper in Berlin detailing that this parasite, which was found in human facial hair follicles, was an acarid and is called demodex folliculorum. After that, there are related studies and findings. In 1919, Stanley Hirst published a monograph on Demodex, introducing 24 Demodex mites known at that time. In 1972, C Desch and NB Nutting classified human Demodex mites as follicular Demodex mites and sebaceous Demodex mites. Human Demodex mites have been found to be normal non-pathogenic parasites in humans for 177 years, although studies on biology, immunology, epidemiology, pathogenicity, treatment methods and the like have not been interrupted, since the medical community has no unified understanding of Demodex mites, and Demodex mites generally do not develop into fatal diseases in clinical diseases, even though many medical workers consider human Demodex mites to be normal non-pathogenic parasites in humans. So that our medical textbook is not clearly discussed, leading to a vague understanding of the generation of medical students who go to clinical work. In the face of the clinical manifestations of acarodermatitis such as whelk (acne), rosacea, large pores, blackheads, skin orange-like changes, skin flushing and the like, if the traditional vague etiology is still followed for treatment, the acarodermatitis cannot be clinically cured, and the repeated root causes appear (see: great cattail blossom, Liu just, Lu Kai. human Dermatophagoides and the clinical research progress of skin health [ J ]. China J. M. T. 2018,29(08):510 +516 + 517.)
Therefore, a product with acne removing effect and mite removing effect is urgently needed in the market, so that the problem that acne is repeatedly attacked and is difficult to eradicate is solved.
Disclosure of Invention
The technical problem to be solved by the invention is to provide an acne removing product with an acarid removing effect, and the problem that acne is repeatedly attacked can be effectively solved.
The specific technical scheme for solving the problems is as follows:
a three-pepper acne-removing and mite-killing agent contains fructus Zanthoxyli (Zanthoxylum BUNGEANUM) fruit extract, Capsici fructus (Capsicum FRUTESCENS) fruit extract, and radix Piper METHYSTICUM (Piper METHYSTICUM) root extract.
The three-pepper acne-removing and mite-removing agent can be prepared by a conventional production process, and in a preferred embodiment of the invention, the three-pepper acne-removing and mite-removing agent comprises the following steps:
(1) drying fructus Zanthoxyli, fructus Capsici, and radix Piper methysticum, and pulverizing to 10-50 mesh to obtain plant powder;
(2) adding water, butanediol, and hexanediol as extraction solvent into the plant powder, extracting, and filtering.
In some embodiments, in the step (2), the extraction is preferably low-temperature high-pressure difference extraction, and comprises the following steps: uniformly mixing the plant powder and the solvent, putting the mixture into an extraction kettle, adjusting the temperature to be 30-50 ℃, pressurizing to 50-100 MPa, soaking and extracting for 10-30 minutes under stirring, centrifuging, collecting supernatant, and filtering and separating.
In some embodiments, the mass ratio of the zanthoxylum bungeanum fruit to the capsicum frutescens fruit to the kava root is (1-10): (1-10): (1-10).
In one embodiment, the mass ratio of the zanthoxylum bungeanum fruit to the capsicum frutescens fruit to the kava root is 1:2: 1.
In some embodiments, the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5.
The invention adopts the low-temperature high-pressure difference method, which is characterized in that the loss of heat-sensitive components can be avoided under the low-temperature condition, the solvent can be more easily permeated into the plant powder under the high-pressure condition, so that the effective components can be quickly dissolved in the solvent, and the experiment proves that the extract obtained by the low-temperature high-pressure difference method has higher active components and better skin care effect.
The three-pepper acne-removing composition disclosed by the invention can reduce grease secretion, ensure that the cuticle is normally peeled off, has a good mite-removing effect, can effectively solve the problem of repeated attack of acne, can be used as an active raw material to be added into a common matrix or carrier of a skin care product, and can be prepared into cosmetics such as acne-removing cream, acne-removing essence, acne-removing water aqua, acne-removing gel, acne-removing facial mask, acne-removing spray, mite-removing spray and the like.
In some embodiments, the three-pepper acne-removing composition is used in the cosmetic in an amount of 1-10 wt%.
The embodiment of the invention also provides an oil-control acne-removing cream which comprises the following components in percentage by mass:
in some of the embodiments, the cream for controlling oil and removing acne further comprises radix Sophorae Flavescentis (Sophora ANGUSTIFOLIA) root extract.
The radix sophorae flavescentis (SOPHORA ANGTIFOLIA) root extract can be a commercially available raw material, and can also be prepared by a conventional method, such as: extracting with water or ethanol for 1-3 times, mixing extractive solutions, and filtering.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, embodiments of the present invention will be described in further detail below, but the embodiments of the present invention are not limited thereto, and process parameters or conditions not particularly noted may be performed with reference to conventional techniques.
The zanthoxylum bungeanum maxim fruit has an inhibiting effect on streptococcus A and B, staphylococcus, pneumococcus, bacillus anthracis, bacillus subtilis, vibrio cholerae, proteus, bacillus paratyphi, bacillus dysenteriae and pseudomonas aeruginosa. The volatile oil has antibacterial effect on bacteria, various dermatophytes and deep fungi, and is most sensitive to Microsporum lanuginosum and Trichophyton rubrum. Skimmianine also has strong antifungal effect. The contained volatile oil can severely poison ascaris suum in the wilfordii solution, and has strong contact poisoning effect on scabies mites.
The capsicum frutescens related by the invention has the effect of inhibiting and killing a plurality of strains such as staphylococcus aureus, dysentery bacterium, typhoid dysentery bacterium, pseudomonas aeruginosa, bacillus subtilis and the like, and can accelerate blood circulation, promote the activity of red blood cells, accelerate skin metabolism, help the healing of damaged tissues and compact skin, promote the close connection between the epidermis and the dermis and inhibit the increase of fat cells.
The kava root related by the invention contains a plurality of amide compounds: the compounds such as piperine, piperamide, piperine, piperoleine, aromatic oil, crude protein, etc. have excellent bactericidal and analgesic effects against Propionibacterium acnes, Pseudomonas aeruginosa, Candida albicans, and Staphylococcus aureus.
The sophora flavescens root related by the invention is rich in alkaloids such as matrine, oxymatrine, hydroxymatrine, N-methyl laburnine, anargine, bayifoline, dehydromatrine, d-isomatrine and matrine, and has the effects of diminishing inflammation, sterilizing and resisting bacteria, regulating immunity, increasing white blood cells and balancing oil secretion.
Example 1
A preparation method of a three-pepper acne-removing and mite-killing agent comprises the following steps:
(1) drying the zanthoxylum bungeanum fruit, the capsicum frutescens fruit and the kava root, wherein the mass ratio of the zanthoxylum bungeanum fruit to the capsicum frutescens fruit to the kava root is 1: 10: 1; pulverizing to 50 mesh to obtain plant powder;
(2) adding water, butanediol and hexanediol into plant powder, wherein the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5; mixing, putting into extraction kettle, adjusting temperature to 30 deg.C, pressurizing to 50MPa, soaking and extracting under stirring for 30 min, centrifuging, collecting supernatant, and filtering with 1000 mesh filter cloth.
Example 2
A preparation method of a three-pepper acne-removing and mite-killing agent comprises the following steps:
(1) drying the zanthoxylum bungeanum fruit, the capsicum frutescens fruit and the kava root, wherein the mass ratio of the zanthoxylum bungeanum fruit to the capsicum frutescens fruit to the kava root is 10: 1: 10; pulverizing to 10 mesh to obtain plant powder;
(2) adding water, butanediol and hexanediol into plant powder, wherein the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5; mixing, putting into extraction kettle, adjusting temperature to 50 deg.C, pressurizing to 100MPa, soaking and extracting under stirring for 10 min, centrifuging, collecting supernatant, and filtering with 500 mesh filter cloth.
Example 3
A preparation method of a three-pepper acne-removing and mite-killing agent comprises the following steps:
(1) drying the pricklyash peel fruits, the capsicum frutescens fruits and the kava roots, wherein the mass ratio of the pricklyash peel fruits, the capsicum frutescens fruits and the kava roots is 1:2: 1; pulverizing to 30 mesh to obtain plant powder;
(2) adding water, butanediol and hexanediol into plant powder, wherein the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5; mixing, putting into extraction kettle, adjusting temperature to 40 deg.C, pressurizing to 80MPa, soaking and extracting under stirring for 20 min, centrifuging, collecting supernatant, and filtering with 800 mesh filter cloth.
Comparative example 1
A preparation method of a three-pepper acne-removing and mite-killing agent comprises the following steps:
(1) crushing the zanthoxylum bungeanum maxim into 30 meshes to obtain plant powder;
(2) adding water, butanediol and hexanediol into plant powder, wherein the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5; mixing, putting into extraction kettle, adjusting temperature to 40 deg.C, pressurizing to 80MPa, soaking and extracting under stirring for 20 min, centrifuging, collecting supernatant, and filtering with 800 mesh filter cloth.
Comparative example 2
A preparation method of a three-pepper acne-removing and mite-killing agent comprises the following steps:
(1) crushing the capsicum frutescens to 30 meshes to obtain plant powder;
(2) adding water, butanediol and hexanediol into plant powder, wherein the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5; mixing, putting into extraction kettle, adjusting temperature to 40 deg.C, pressurizing to 80MPa, soaking and extracting under stirring for 20 min, centrifuging, collecting supernatant, and filtering with 800 mesh filter cloth.
Comparative example 3
A preparation method of a three-pepper acne-removing and mite-killing agent comprises the following steps:
(1) pulverizing kava root to 30 mesh to obtain plant powder;
(2) adding water, butanediol and hexanediol into plant powder, wherein the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5; mixing, putting into extraction kettle, adjusting temperature to 40 deg.C, pressurizing to 80MPa, soaking and extracting under stirring for 20 min, centrifuging, collecting supernatant, and filtering with 800 mesh filter cloth.
Comparative example 4
A preparation method of a three-pepper acne-removing and mite-killing agent comprises the following steps:
(1) drying the pricklyash peel fruits, the capsicum frutescens fruits and the kava roots, wherein the mass ratio of the pricklyash peel fruits, the capsicum frutescens fruits and the kava roots is 1:2: 1; pulverizing to 30 mesh to obtain plant powder;
(2) adding water, butanediol and hexanediol into plant powder, wherein the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5; mixing, soaking and extracting in extraction kettle at room temperature for 20 min under stirring, centrifuging, collecting supernatant, and filtering with 800 mesh filter cloth.
Test 1 mite removal test
(1) Acquisition of human demodex: adopting a transparent adhesive tape sticking method to obtain the demodex, and specifically comprising the following steps: the examinee is asked to wash his face before sleeping, then the transparent adhesive tapes with the length of 6cm and the width of 1.5cm are respectively stuck on the forehead, the cheek, the nose, the chin and the like, and then the transparent adhesive tapes are stuck on the adhesive tapes after being taken off the adhesive tapes the next morning for microscopic examination.
(2) Grouping tests: the extracts obtained in examples 1-3 and comparative examples 1-4 were diluted to 1% dilution with water as a solvent, respectively, and a blank was set. 200 microliters of 1% diluent is dripped into each glass slide, so that the diluent is uniformly spread and the diluent is ensured to be fully contacted with the worm body. Placing in an environment with relative humidity of 70-80% and temperature of 26-28 deg.C, taking out after 1 hr, and observing demodex survival condition under microscope. After continuously observing under a 400X microscope for 3min, the dead insect is judged to be dead by the dead insect. Several specific tests are shown in table 1 below.
TABLE 1 mite-killing test recording sheet
As can be seen from Table 1, the combination of pricklyash peel, capsicum frutescens and kava root has the best mite-killing effect.
Example 4
The oil-control acne-removing cream comprises the following components in percentage by mass:
example 5
The oil-control acne-removing cream comprises the following components in percentage by mass:
example 6
The oil-control acne-removing cream comprises the following components in percentage by mass:
example 7
The oil-control acne-removing cream comprises the following components in percentage by mass:
the radix sophorae flavescentis (SOPHORA ANGTIFOLIA) root extract is prepared by the following method, for example: extracting with 75vt% ethanol under stirring for 3 times, mixing extractive solutions, and filtering.
Test 2 oil control acne removal test
The oil control and acne removal creams prepared in examples 4-7 and the blank control were evaluated for oil control efficacy. The blank control group is different from the blank control group in example 6 in that the three-pepper acne-removing and mite-eliminating agent is not contained.
Testing an instrument: german CK company skin oil tester Sebumeter SM 815. The working principle of the skin cuticle oil absorption rubber belt is that a special rubber belt is adopted, oil on the surface of the skin cuticle can be absorbed quickly, the transmittance of the rubber belt can be changed by the oil, and the oil content of the skin cuticle can be obtained by measuring the transmittance of the rubber belt before and after use through a photometer arranged in an instrument.
The test method comprises the following steps: the oil-control acne-removing cream is applied to the face at a dosage of 0.1 g/time and is gently massaged until the cream is absorbed, wherein 40 volunteers with oily skin and whelk are recruited and divided into 4 groups of 10 people in each group, and the oil-control acne-removing cream is respectively used once in the morning and at night. The acne removing condition is recorded by taking a picture every 1 week (the acne number is reduced by more than 1/3 and is judged to be effective by comparing with the picture before using the product), the oil content of the forehead of the volunteer is measured by a skin oil tester, each part is tested for 3 times, and the average value is taken.
The specific test records are shown in the following tables 2 and 3.
TABLE 2 oil control test recording table
TABLE 3 acne-removing test record sheet
As can be seen from tables 2 and 3, the oil-controlling acne-removing cream prepared by the embodiment of the invention has good oil-controlling acne-removing effect.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in any way, so that any simple modification, equivalent change and modification made to the above embodiment according to the technical spirit of the present invention will still fall within the scope of the technical solution of the present invention without departing from the content of the technical solution of the present invention.
Claims (6)
1. A three-pepper acne-removing and mite-removing agent is characterized by comprising an extract of fruit of Zanthoxylum BUNGEANUM (Zanthoxylum BUNGEANUM), an extract of fruit of Capsicum FRUTESCENS (Capsicum FRUTESCENS), and an extract of root of Piper METHYSTICUM (Piper METHYSTICUM);
the preparation method of the three-pepper acne-removing and mite-killing agent comprises the following steps:
(1) drying the pricklyash peel fruits, the capsicum frutescens fruits and the kava roots, wherein the mass ratio of the pricklyash peel fruits, the capsicum frutescens fruits and the kava roots is (1-10): (1-10): (1-10); pulverizing to 10-50 mesh to obtain plant powder;
(2) adding water, butanediol and hexanediol into plant powder as an extraction solvent for extraction, wherein the mass ratio of the plant powder to the water, the butanediol and the hexanediol is 1:15:5: 0.5; and then filtered.
2. The three-pepper acne-removing and mite-eliminating agent according to claim 1, wherein in the step (2), the extraction is performed by a low-temperature high-pressure-difference method, and comprises the following steps: uniformly mixing the plant powder and the solvent, putting the mixture into an extraction kettle, adjusting the temperature to be 30-50 ℃, pressurizing to 50-100 MPa, soaking and extracting for 10-30 minutes under stirring, centrifuging, collecting supernatant, and filtering and separating.
3. The three-pepper acne removing and mite removing agent according to claim 1, wherein in the step (1) of the preparation method of the three-pepper acne removing and mite removing agent, the mass ratio of the zanthoxylum bungeanum fruit, the capsicum frutescens fruit and the kava root is 1:2: 1.
4. The three-pepper acne-removing and mite-removing agent as defined in claim 1, wherein the three-pepper acne-removing and mite-removing agent is used for preparing cosmetics.
5. The oil-control acne-removing cream is characterized by comprising the following components in percentage by mass:
6. the cream of claim 5, further comprising an extract of the root of Sophora flavescens (Sophora ANGUSTIFOLIA).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910737287.9A CN110420266B (en) | 2019-08-11 | 2019-08-11 | Acne-removing and mite-removing agent with three kinds of pepper |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910737287.9A CN110420266B (en) | 2019-08-11 | 2019-08-11 | Acne-removing and mite-removing agent with three kinds of pepper |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110420266A CN110420266A (en) | 2019-11-08 |
| CN110420266B true CN110420266B (en) | 2021-07-16 |
Family
ID=68415379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910737287.9A Active CN110420266B (en) | 2019-08-11 | 2019-08-11 | Acne-removing and mite-removing agent with three kinds of pepper |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110420266B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111329807A (en) * | 2020-04-02 | 2020-06-26 | 广州市逸轩精细化工有限公司 | Acne removing cream and preparation method thereof |
| CN111617010A (en) * | 2020-07-23 | 2020-09-04 | 广州市轩颜化妆品有限公司 | Foot periostracum and preparation method thereof |
| CN112006934A (en) * | 2020-09-04 | 2020-12-01 | 江苏美爱斯化妆品股份有限公司 | Cosmetic compound with mild acne removing effect and application thereof |
| CN111991302A (en) * | 2020-09-23 | 2020-11-27 | 广东大澳生物科技有限公司 | Acne removing gel and preparation method thereof |
| CN113197804A (en) * | 2021-04-29 | 2021-08-03 | 钟意生物技术(广州)有限公司 | Plant repair factor and application thereof |
| CN113208992A (en) * | 2021-05-11 | 2021-08-06 | 广州杨森药业有限公司 | Mild acne-removing mite-removing goat milk soap and preparation method thereof |
| CN115006314B (en) * | 2022-07-11 | 2023-07-11 | 科乐美(广州)生物科技有限公司 | Kava pepper extract and preparation method and application thereof |
| FR3139467A1 (en) * | 2022-09-09 | 2024-03-15 | Crodarom | Use of a Sichuan pepper extract for skin treatment and a composition adapted to this use. |
| WO2024052756A1 (en) * | 2022-09-09 | 2024-03-14 | Crodarom | Use of an extract of sichuan pepper for a skin treatment and a composition suitable for this use. |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101977618A (en) * | 2008-01-16 | 2011-02-16 | A·礼萨伊-法尔德 | Composition for treating a skin disorder |
| CN103920079A (en) * | 2014-04-25 | 2014-07-16 | 西南大学 | Traditional Chinese medicine composition for treating canine demodicidosis and preparation as well as preparation method and application thereof |
| CN108186510A (en) * | 2018-03-31 | 2018-06-22 | 佛山娇芙生物科技有限公司 | A kind of aloe oil control and acne removal composition |
| CN109620881A (en) * | 2019-02-02 | 2019-04-16 | 广州富煜陇化工科技有限公司 | It is a kind of to have effects that the compound plant extract of antiphlogistic antibacterial and its application |
-
2019
- 2019-08-11 CN CN201910737287.9A patent/CN110420266B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101977618A (en) * | 2008-01-16 | 2011-02-16 | A·礼萨伊-法尔德 | Composition for treating a skin disorder |
| CN103920079A (en) * | 2014-04-25 | 2014-07-16 | 西南大学 | Traditional Chinese medicine composition for treating canine demodicidosis and preparation as well as preparation method and application thereof |
| CN108186510A (en) * | 2018-03-31 | 2018-06-22 | 佛山娇芙生物科技有限公司 | A kind of aloe oil control and acne removal composition |
| CN109620881A (en) * | 2019-02-02 | 2019-04-16 | 广州富煜陇化工科技有限公司 | It is a kind of to have effects that the compound plant extract of antiphlogistic antibacterial and its application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110420266A (en) | 2019-11-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110420266B (en) | Acne-removing and mite-removing agent with three kinds of pepper | |
| KR102096414B1 (en) | Cosmetic composition for improving of acne skin | |
| KR20080002279A (en) | Lip cosmetic composition for atopy skin | |
| CN111973515B (en) | Bacteriostatic restoration plant extraction composition, preparation method and application thereof | |
| CN106177100B (en) | Composition with acne removing effect and application thereof | |
| KR20130030032A (en) | Cosmetic compositions comprising extracts of hubs | |
| Rahman et al. | Comparative antimicrobial activity of Areca catechu nut extracts using different extracting solvents | |
| CN111991334A (en) | Skin-care matrix and preparation method and application thereof | |
| KR100712249B1 (en) | Oily to acne skin cosmetics composite containing oriental herb extract and manufacturing method thereof | |
| Sari et al. | Acute dermal toxicity study of Areca catechu Linn. Extract in sprague-dawley rats | |
| KR100962344B1 (en) | Cosmetic composition for removing blackhead | |
| KR101533195B1 (en) | Wet Tissue composition for the Natural preservative | |
| KR102162904B1 (en) | Hair coloring composition and the manufacturing process having antimicrobial and antiflammatory and deodorizing activity and ammonia odor removal effet | |
| KR102282642B1 (en) | Cosmetic composition containing the extract of 5 aromatic herbs and 5 medicinal herb | |
| KR102380585B1 (en) | Anti-inflammatory, soothing, and antibacterial functional cosmetic composition using natural herbal mixture extract as an active ingredient | |
| KR102228086B1 (en) | Hair coloring composition having antimicrobial and deodorizing activity and ammonia odor removal effet | |
| KR20100120451A (en) | Antibiotic composition containing herbal medicine extracts | |
| KR101574248B1 (en) | Cosmetic composition comprising Reynoutria sachalinensis extracts for skin anti-wrinkle effect | |
| EP2788011B1 (en) | Composition comprising a chelidonium majus extract and copaiba, and the use thereof for the treatment of cutaneous dysfunctions | |
| JP6391879B1 (en) | Beauty method | |
| KR102095988B1 (en) | A purple cosmetic composition for skin smoothing comprising an active ingredient of a plant complex extract | |
| KR102504441B1 (en) | A method of manufacturing a lactobacillus additive comprising cosmos-derived lactobacillus and sage extract, and a method of manufacturing a cosmetic composition comprising the same | |
| CN113712858B (en) | Preparation and application of antibacterial and anti-inflammatory plant extract composition | |
| KR102619073B1 (en) | Natural plant extract preservative system for cosmetics comprised of Honeysuckle, Anise, Lichen and Basil, and its manufacturing process | |
| Randima et al. | In Vitro Evaluation and Comparison of Antibacterial Activity of the Novel Herbal Aqueous Creams Containing Aqueous Extracts of the Leaves of Ficus religiosa L. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |