KR100712249B1 - Oily to acne skin cosmetics composite containing oriental herb extract and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a cosmetic composition for improving oily skin and a method of manufacturing the same. The cosmetic composition for improving oily skin according to the present invention is characterized by containing rhubarb, red ginseng, rhubarb, and extract of Changsha, and the method for preparing the composition comprises the steps of preparing a mixture of rhubarb, red ginseng, rhubarb and Changsha; And adding an extraction solvent to the mixture and extracting an active ingredient. Oily skin improvement extract according to the present invention showed an excellent effect in the evaluation of pores shrinkage effect, anti-inflammatory effect and anti-acne effect of the skin, oily skin improvement cosmetic composition containing such extract is not only safe for the skin, sebum It suppresses the excessive secretion of and has an excellent acne bacteria inhibitory effect.

Oily skin, cosmetics, pore shrinkage, anti-inflammatory, anti-acne

Description

Cosmetic composition for improving oily skin containing herbal extracts and a method of manufacturing the same {Oily to acne skin cosmetics composite containing oriental herb extract and manufacturing method

The present invention relates to a cosmetic composition for improving oily skin and a method for manufacturing the same, and more particularly, to a cosmetic composition for improving oily skin including an active ingredient of an extract of rhubarb, red ginseng, yellow lotus, and changja.

Clear and clean skin is the desire of all ages, but in reality, it is not common for people with such skin. Each person has a variety of skin problems, but among them, the wide pores are considered to be the biggest enemy of the skin because the face looks dirty and makeup is easily erased, and once widened, it is hard to get smaller. Accordingly, consumers' interest in the pores is gradually increasing, and reducing the size of the pores can be said to be one of the important tasks that cosmetics in pursuit of women's beauty must solve.

The reason for the widening of pores is that as collagen fibers and elastic fibers supporting the pores wall degenerate and gradually decrease as skin aging begins, skin elasticity is lost and swelled, causing the pores to appear stretched or excessive sebum secretion. The skin surface contains sebum, which is a sebaceous gland-derived lipid such as triglyceride, squalene, and wax ester, and skin lipid, which is an epidermal-derived lipid produced in epidermal cells such as phospholipid, cholesterol, and cholesterol ester.

Sebum forms a thin sebum film on the surface of the epidermis, prevents the ingress of foreign substances, protects the skin from the irritation of various substances, and also has a lubrication effect on the skin surface and a water vapor suppression effect. However, sebum may generate lipid peroxide by UV rays and may cause skin trouble, and bacteria such as propionibacterium acnes, which are always present on skin due to excessive sebum secretion due to sebaceous gland hyperfunction, Acne is formed by breaking down triglycerides in the liver, causing inflammation. The triglyceride component in sebum is broken down into free fatty acid by lipase produced by acne bacteria, and keratinization proceeds to the surface of the skin due to the stimulus.

In the recent cosmetic development, it uses natural products to nourish the skin, minimize the toxic effects of cosmetics obtained by chemical synthesis, reduce side effects, and use pure herbal prescriptions to treat various symptoms of the skin. There is a high interest in the development of herbal cosmetics. However, on the other hand, without the proper knowledge about herbal medicines and skin, simply using a beauty pack for beauty without consulting with an expert, and the resulting side effects of the skin is also serious.

The present invention has been devised under the technical background that spurs the development of cosmetics that can achieve the above oily skin improvement effect.

Therefore, the technical problem to be achieved by the present invention is to provide a nutritional and therapeutic effect by providing nutrition to the skin while preventing the skin keratinization while reducing the pore size, in order to achieve the technical problem, skin side effects It is an object of the present invention to provide a herbal composition extract containing cosmetic composition and a method for producing the same, which is excellent in improving oily skin while having less.

In order to achieve the above technical problem, the present invention provides a cosmetic composition for improving oily skin, characterized in that it contains extracts of rhubarb, ginseng, yellow lotus and changja.

The present invention also provides a cosmetic composition for improving oily skin, characterized in that the content of each of the extracts of rhubarb, ginseng, rhubarb and changja is 10 to 50% by weight relative to the total weight of the extract.

The present invention also provides a cosmetic composition for improving oily skin, wherein the content of the extract is 0.001 to 10% by weight relative to the total weight of the cosmetic composition.

The present invention also comprises the steps of preparing a mixture of rhubarb, red ginseng, rhubarb and Chang Chang; And adding an extracting solvent to the mixture and extracting an effective ingredient.

The present invention is a step of preparing a mixture of the above-described manufacturing method, wherein the content of the rhubarb, ginseng, rhubarb and Changja each of the content of the oily skin improvement extract, characterized in that 10 to 50% by weight relative to the total weight of the mixture to provide.

The present invention provides a method for producing an oily skin improvement extract, characterized in that in the extracting step of the above-described manufacturing method, the extraction is performed by immersion extraction for 1 to 15 days at a temperature of 5 to 37 ℃.

The present invention provides a method for producing an oily skin improvement extract, characterized in that in the extracting step of the above-described manufacturing method, the extraction is extracted for 1 to 20 hours at a temperature of 50 to 95 ℃.

Hereinafter, the cosmetic composition for improving the oily skin of the present invention and a manufacturing method thereof will be described in detail.

The present invention is based on the theoretic theory that the excessive secretion of sebum, which is often found in oily skin, appears to be congested with heat. These fevers include winds that are congested in the skin or belong to the realm of real heat such as moist fever of the stomach and moist fever of the liver, and blood fever of the blood, lung, liver and god. It can be classified as belonging to the category of fever.

The present invention is also based on the principle of military affairs company (君臣 佐使) based on combining a plurality of drugs in a single medicine to form a prescription. Here, the group means military drugs (君 藥), which is the main drug in one prescription, and is suitable for typical symptoms. The New Drug is a drug that aids and strengthens the effect of the military drug, the main action drug. Suppositories (佐 藥) is a drug that is used to relieve the toxicity of toxic drugs, or to eliminate the symptoms associated with the main symptoms. Drugs (使 藥) is to guide the action site of the prescription to the disease site and to act to neutralize various drugs. This is called control science in oriental medicine.

The present invention is to distinguish between the medicinal properties of herbal medicines into three groups: Gi, beauty, and color, to distinguish between the properties of drugs. Rhubarb, ginseng, rhubarb and rhubarb selected from 50 kinds of medicinal herbs such as fruit root, omae, rhubarb, Uiin, Baekje, Gosam, Hwangnyeon, Changjaja, Bupyeongcho, Baekji, selected based on the principle of military affairs for synergy Changzai extract has pore contraction effect, anti-inflammatory effect and anti-acne effect that inhibits sebum, and the cosmetic composition containing it is not only safe for skin but also inhibits excessive secretion of sebum and shows excellent acne bacteria suppression effect. Based on.

The cosmetic composition for improving oily skin of the present invention contains extracts of rhubarb, ginseng, yellow lotus and changja.

The medicinal herbs used in the preparation of the herbal extracts contained in the cosmetic composition for improving oily skin of the present invention can be easily purchased on the market, `` The Ingredients and Uses of Herbs '' (Ilwol Seok, 1991), 『Korean Herbs』 The pharmacological effects that are known through the Books of Gamhak (1998, 1998), Herbal Resources Botany (Hakhak Publication, 1999), and Herbal Medicines Standards Collection (Korea Pharmaceutical Import and Export Association and Korea Institute for Drug Testing, 2000) are as follows. .

Rhubarb (大黃, Rhei Rhizoma) extracted and contained in the cosmetic composition of the present invention is the root of Polygonaceae Rheum undulatum L. Remove the shells and burdock-shaped roots of 6--7 years old roots and use them as sliced or whole. It is a perennial herbaceous plant with thick yellow roots and the height of straight stems reaches 1m. It is hollow and the leaf shape is a wide egg-shaped round shape, and the leaf body length is 25-30 cm. Leaf veins on the back are clear, rarely dull teeth on the edges, and blunt ends. Flowers bloom in July-August, with yellowish white flowers with peduncles returned from flower heads. The basement has many burdock roots attached to the vertical roots. Fruits are capsules, triangular in shape, with wings, ripening in August. It is native to China, Qinghai, and grows in valley wetlands. Main components are anthraquinone derivatives, their glycosides, and tannins. Anthraquinone derivatives have diarrhea and tannins are astringent and dry. Rhubarb is known to cure fever and to have potent detoxification effects, which is expected to be effectively used for various skin diseases caused by oily skin.

The extracted ginseng (苦 蔘, Sophorae Radix) contained in the cosmetic composition of the present invention is the root of the legumes ( Leuminosae ) ginseng ( Sophora angustifolia S. et Z.) as it is, or mostly peeled off the skin. It is distributed in sunny meadows throughout Korea, Japan, and China. It is a perennial herb and grows to about 80 to 100 cm in height. Stems are green but black when they are young, straight, leaves are alternate, oddly littered leaves. The flowers are light yellow in June to August, and the stems of about 20cm emerge from the end of the branches. Fruits are short in Sep.-Oct, ripen in 7-8cm long, and are in the shape of beads. It contains alkaloids, flavonoids, d-matrin, d-oxymatrin, etc., and macchiine-based substances have anti-dermal fungal action. Antibacterial, anti-inflammatory, anti-allergic, anti-cancer, diuretic and cardiovascular effects are known for its effects of cooling and humidity control and swelling and insecticidal treatment. It is expected to inhibit sebum secretion by inhibiting hormone secretion.

Goldthread contained in the cosmetic composition of the present invention is extracted (黃連, Coptidis Rhizoma) is the rhizome of Ranunculaceae (Ranunculaceae) goldthread (Coptis japonica M.). It is called perennial because it is a perennial plant with yellow roots. Perennial herb, leaves 5-9 cm long, 7-10 cm wide, gathered at the end of rhizomes. Stems have no terrestrial diameter, short roots, and many small roots. Flower is pink in April-May, fruit is capsule-shaped, wide oval, the end is long like root, and seed is oval-shaped black. Alkaloids of berberine (C ₂ 0H ₁₉ O ₅ N) and the like. Berberine of Huang Yan has blood pressure lowering, strong heart, antipyretic, antibacterial, soothing and anti-inflammatory action, and is said to kill skin fungi and white candida. As such, sulfur is known as a representative drug having antibacterial, antiviral, anti-inflammatory and antipyretic effects, which is expected to be useful for various inflammatory diseases occurring in oily skin.

Changza (Xanthii Fructus), which is extracted and contained in the cosmetic composition of the present invention, is the fruit of the Compositae ( Xanthium strumarium L.). It is an annual herb that grows in Korea, Japan, and China. Light green flowers bloom in summer and the fruit ripens in the fall. The most commonly used folk herb, which is picked from dried fruit in the fall. It is called Changi-za, Shii-sil, Ho-sil, Ji-gyu, seal, and boss. It is known as a medicine for leprosy, sinusitis, rhinitis, arthritis. Xanthostrumarin (Xanthostrumarin), fatty oils (linoleic acid, oleic acid, saturated fatty acids), tannins, alkaloids, proteins, sugars, vitamin C, sulfate compounds, pigments, etc. It is a plant with high iodine content. Hypoglycemia, anti-inflammatory, analgesic, antibacterial, anti-cancer and cardiovascular effects, blood and respiratory tract and rash and pruritis caused by the customary fever, due to acne skin It is expected that sebum will be useful for local inflammation caused by clogging pores.

The cosmetic composition of the present invention is preferably in the extract of rhubarb, ginseng, rhubarb and Chang-za, each content of 10 to 50% by weight relative to the total weight of the extract. When the content of any one herbal extract is less than 10% by weight, the content of the herbal medicine is relatively low, which is not preferable because it is not possible to sufficiently achieve the original desired effect, and the content of any one herbal extract exceeds 50% by weight. In this case, the content of other herbal medicines may be relatively low, so that the original desired pore contraction, anti-inflammatory and anti-acne bacteria effects may not be sufficiently achieved.

On the other hand, the cosmetic composition of the present invention is that the content of the extract of rhubarb, ginseng, rhubarb and Chang Changja is preferably 0.001 to 10% by weight relative to the total weight of the cosmetic composition. If the content of the extract is less than 0.001% by weight, it is not preferable because the original desired effect may not be sufficiently achieved. If the content of the extract is more than 10% by weight, it may cause a problem in the stability of the cosmetic composition. Due to this may cause problems in the appearance of the cosmetic composition or may not produce a sufficient cosmetic effect when used.

The cosmetic composition for improving oily skin of the present invention may be prepared in various formulations such as cosmetics, creams, face wash cosmetics, packs, foundations, makeup bases, and the like, and specifically, liquid, cream, paste, solid, etc. Applicable to various features. It is also possible to prepare a cosmetic composition containing the extract of rhubarb, ginseng, rhubarb and changja of the present invention using a conventional cosmetic preparation method.

The present invention also comprises the steps of preparing a mixture of rhubarb, red ginseng, rhubarb and Chang Chang; And extracting an active ingredient by adding an extraction solvent to the mixture.

In the step of preparing a mixture of the production method according to the present invention, the contents of rhubarb, ginseng, rhubarb and changja are preferably 10 to 50% by weight based on the total weight of the mixture. If the content of any one herbal extract is less than 10% by weight, the content of the herbal medicine is relatively low, there is a risk that the original desired effect can not be achieved sufficiently, if the content of any herbal medicine exceeds 50% by weight There is a fear that the relatively low content of other herbal medicines may not achieve a relatively sufficient effect of the intended pore contraction, anti-inflammatory and anti-acne bacteria.

Extraction solvent used in the step of extracting the preparation method according to the invention is purified water and carbon atoms containing methanol, ethanol, pre- ethylene glycol, propyl alcohol, butylene glycol, butyl alcohol, glycerin and the like It is preferable to use at least one solvent selected from the group consisting of alcohols, and the extraction solvent is preferably added in an amount of 1 to 20 times the total weight of the herbal mixture. If the amount of the extraction solvent is less than 1 times the total weight of the herbal mixture, it is not preferable that the whole herbal medicine is difficult to be evenly extracted to achieve the original desired extraction effect, and the content of the extraction solvent exceeds 20 times the total weight of the herbal mixture. After extraction, the content of the active ingredient may be low, so there may be a problem in displaying the desired effect.

Extraction method used in the extraction step of the manufacturing method according to the present invention is similar to the cold leaching method, a certain time leaching at a relatively low temperature, but a cold leaching method similar to the cold leaching method, the leaching at a temperature of 35 to 45 ℃, 60 to 120 A heat extraction method that leaches at a temperature of ℃, a percolation method using a percolater (percolater) and the like can be used, but is not limited thereto.

More specifically, the above-mentioned extraction method is added to the mixture of rhubarb, ginseng, rhubarb and Changjaja, and then proceeded by immersion extraction for 1 to 15 days at a temperature condition of 5 to 37 ℃, or rhubarb, ginseng, rhubarb And adding an extraction solvent to the mixture of Changiza and mounting a cooling capacitor, and then proceeding with extraction by applying heat for 1 to 20 hours at a temperature of 50 to 95 ° C. Both room temperature extraction and heating extraction are preferred when extracting the mixture of rhubarb, red ginseng, rhubarb and Changija by using an extraction solvent, but the effective ingredient is effective if the extraction temperature is too low or the extraction time is too short, whether it is a room temperature extraction method or a heat extraction method. It is not preferable because it can not achieve the desired desired extraction effect because it is not extracted, and even if the extraction temperature is higher or the extraction time is longer than the condition that the effective ingredient is extracted effectively, the extracted active ingredient does not affect the extracted active ingredient. It is not desirable to extract under severe conditions than under conditions that are sufficiently effective to extract.

Hereinafter, the present invention will be described in detail with reference to Examples. However, embodiments according to the present invention can be modified in many different forms, the scope of the present invention is not limited to the examples described below.

Extraction Examples 1-3

After weighing 1000 g of the selected rhubarb and putting it in the extractor, 5 kg of each extraction solvent as shown in Table 1 was added. After immersion and extraction at room temperature for 6 days, the mixture was filtered through a 400 mesh filter cloth, left at 4 ° C. for 7 days, and aged at low temperature, followed by secondary filtration with a 0.45 μm filter. The extraction filtrate was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling capacitor to obtain rhubarb extracts in powder form as shown in Table 1 below.

Extraction Example Extraction solvent Rhubarb Extract (g) One 30% water ethanol 35.0 2 70% water ethanol 32.5 3 30% water butylene glycol 28.6

Extraction Examples 4-6

1000 g of selected ginseng was quantified and placed in an extractor, and 5 kg of each extraction solvent as shown in Table 2 was added. After immersion and extraction at room temperature for 6 days, the mixture was filtered through a 400 mesh filter cloth, left at 4 ° C. for 7 days, and aged at low temperature, followed by secondary filtration with a 0.45 μm filter. The extract filtrate was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling capacitor to obtain a powder of red ginseng extract as shown in Table 2 below.

Extraction Example Extraction solvent Red ginseng extract (g) 4 30% water ethanol 29.5 5 70% water ethanol 32.7 6 30% water butylene glycol 22.1

Extraction Examples 7-9

1000 g of the selected yellow lotus was quantified and placed in an extractor, and 5 kg of each extraction solvent as shown in Table 3 was added. After immersion and extraction at room temperature for 6 days, the mixture was filtered through a 400 mesh filter cloth, left at 4 ° C. for 7 days, and aged at low temperature, followed by secondary filtration with a 0.45 μm filter. The extract filtrate was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling capacitor to obtain powdered yellow lotus extracts as shown in Table 3 below.

Extraction Example Extraction solvent Sulfur Extract (g) 7 30% water ethanol 35.4 8 70% water ethanol 32.6 9 30% water butylene glycol 23.7

Extraction Examples 10-12

After weighing 1000 g of the selected window and putting it in the extractor, 5 kg of each extraction solvent as shown in Table 4 was added. After immersion and extraction at room temperature for 6 days, the mixture was filtered through a 400 mesh filter cloth, left at 4 ° C. for 7 days, and aged at low temperature, followed by secondary filtration with a 0.45 μm filter. The extract filtrate was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling capacitor to obtain Changja extracts in powder form as shown in Table 4 below.

Extraction Example Extraction solvent Changiza Extract (g) 10 30% water ethanol 39.4 11 70% water ethanol 37.1 12 30% water butylene glycol 25.2

Extraction Examples 13-15

250 g of selected rhubarb, 250 g of red ginseng, 250 g of yellow lotus and 250 g of Changza were quantitatively placed in an extractor, and 5 kg of each extraction solvent as shown in Table 5 was added thereto. After immersion and extraction at room temperature for 6 days, the mixture was filtered through a 400 mesh filter cloth, left at 4 ° C. for 7 days, and aged at low temperature, followed by secondary filtration with a 0.45 μm filter. The extract filtrate was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling capacitor to obtain a mixed extract in powder form as shown in Table 5 below.

Extraction Example Extraction solvent Mixed Extract (g) 13 30% water ethanol 32.3 14 70% water ethanol 34.0 15 30% water butylene glycol 23.8

Experimental Example 1. In vitro  Pore Shrinkage Effect Test

Using the albumin as a protein to replace the skin to determine the pore shrinkage effect of the degree of aggregation of albumin, and evaluated the pore contraction effect of the herbal extracts obtained according to Examples 3, 6, 9, 12 and 15 described above.

After 0.3% albumin was dissolved in 0.05M citric acid buffer (pH 4.5), 1 ml of an extract sample containing 2 mg of solid content was added to 2 ml of 0.3% albumin solution. After stirring for 5 minutes, the absorbance was measured with an UV-Visible spectrophotometer in the wavelength band of 650 nm. The control group for the pores shrinkage test was measured in the same way to put the citric acid buffer solution instead of the herbal medicine extract sample, the buffer solution instead of the albumin solution was obtained by each color correction value for the herbal medicine extract sample and the control. The measurement results are shown in Table 6, and the greater the absorbance value, the better the pore contraction effect.

Extraction Example Extract sample Solid content (mg) of extract contained in reaction solution Absorbance Control Citric Acid Buffer - 0.0002 3 Rhubarb extract 2.0 0.3827 6 Ginseng extract 2.0 0.0010 9 Yellow lotus extract 2.0 0.0005 12 Changiza Extract 2.0 0.0049 15 Rhubarb + Ginseng + Red Lotus + Spear Extract 2.0 0.4747

As shown in Table 6, the absorbance of the four extracts of rhubarb, ginseng, yellow lotus, and Chang-za were higher than those of each single extract of rhubarb, ginseng, yellow lotus, and Chang-za. It can be seen that the extracts of rhubarb, ginseng, rhubarb and changja have relatively good pore contraction effect.

Experimental Example 2. In vitro  Anti-inflammatory effect evaluation test

Inhibition of lipoxygenase activity was measured to confirm the anti-inflammatory effect of the herbal extracts obtained according to Examples 3, 6, 9, 12 and 15 described above.

Inflammation-producing factors due to enzyme activity are the main causes of inflammation. Structural proteins, including phospholipids of cell membranes, produce large amounts of free radicals through pathways that degrade them by enzymes that break them down, ultraviolet rays, or other environmental conditions, thereby increasing the degree of inflammation. That is, the anti-inflammatory effect of the composition of the present invention was evaluated by measuring the inhibition rate of lipoxygenase activity, which is a factor of inflammation.

Determination of the inhibitory effect of lipoxygenase was performed as follows. 0.1 ml of an extract sample containing 0.2 mg of solid content in 1 ml of 1 mM linoleic acid and 0.9 ml of 50,000 units / ml lipoxygenase dissolved in 0.1 M sodium phosphate buffer (pH 7.0) were added. The reaction was carried out in a water bath for 10 minutes. 0.5 ml of 20% (w / v) trichloroacetic acid was added to terminate the reaction, 1 ml of 0.6% (w / v) thiobarbituric acid (TBA) was added and developed in boiling water for 10 minutes. I was. Thereafter, the mixture was cooled in ice water for 2 minutes, 2 ml of n-butanol was added thereto, and the mixture was shaken and then centrifuged at 3,500 rpm for 5 minutes. The upper layer (n-butanol layer) was taken to measure absorbance at a wavelength of 535 nm ultraviolet-visible spectrophotometer to evaluate the inhibitory effect of lipoxygenase.

The control group for the anti-inflammatory effect test was measured in the same manner by adding a buffer instead of the sample solution, the buffer was added instead of lipoxygenase to obtain the respective color correction values for the sample and the control. The anti-inflammatory effect was calculated numerically using Equation 1 shown in Table 7 below.

Extraction Example Extract sample Solid content (mg) of extract contained in reaction solution % Inhibition 3 rhubarb 0.2 13 6 Gosam 0.2 16 9 goldthread 0.2 - 12 Changza 0.2 35 15 Rhubarb + Ginseng + Red Lotus + Spear 0.2 26

As shown in the results of Table 7, the active inhibition rate of rhubarb 13%, red ginseng 16%, and changja 35% of lipoxygenase was shown for rhubarb, red ginseng, rhubarb and changja respectively. The inhibitory effect of lipoxygenase did not appear at the experimental concentration. On the other hand, 4% of the extracts of rhubarb, ginseng, rhubarb, and changja were found to inhibit the activity of lipoxygenase. These results show that the mixed herbal medicine extract of the present invention has a superior anti-inflammatory effect in comparison to each single herbal extract in addition to the Chang-za extract, indicating that the anti-inflammatory effect is higher than the simple average value of the inhibition rate for each single extract.

Experimental Example 3. Antibacterial activity test for acne bacteria (minimum inhibitory concentration (MIC) measurement)

The anti acne bacterium effect on the herbal extracts obtained according to Examples 3, 6, 9, 12 and 15 described above was tested. Acne strains used in this experiment was Propionibacterium acnes ( KCTC 3314), and a minimal inhibitory concentration (MIC) measurement method was used to check the antimicrobial activity. Acne bacteria were used from Korea Collelction for Type Cultures (KCTC).

The measurement of the minimum inhibitory concentration to evaluate the antimicrobial activity against acne bacteria was performed as follows.

In order to activate the acne bacteria was cultured for 48 hours in BHI (brain heart infusion) liquid medium. Each of the extracted herbal medicine extracts was prepared as a sample solution by disinfection filter, and then inoculated with a 1% concentration of acne bacteria pre-cultured in the sample solution. After culturing for 3 days in 37 ℃ anaerobic culture tank, the degree of growth of acne bacteria was observed, and the results are shown in Table 8.

Extraction Example Extract Sample Solid content concentration (%) of the sample contained in reaction liquid 0.05 0.02 0.01 0.005 0.001 3 rhubarb - + + + + 6 Gosam - - - + + 9 goldthread - - - + + 12 Changza - + + + + 15 Rhubarb + Ginseng + Red Lotus + Spear - - - - +

(-) In Table 8 means the killing of acne bacteria, and (+) means that the bacteria are present without being killed. As shown in the results in Table 8, for each single extract of rhubarb, red ginseng, rhubarb, and Chang-za, MICs were shown at concentrations of rhubarb 0.05%, red ginseng 0.01%, rhubarb 0.01% and Chang-za 0.05%. The mixed extracts of the four types of L. and Changiza showed MIC at 0.005%, which is about 2 times lower than the L. From this, it can be confirmed that rhubarb, ginseng, rhubarb, and changja extracts have excellent antimicrobial effects against acne bacteria compared to each single extract.

As a result of Experimental Examples 1 to 3, the mixed extracts of rhubarb, ginseng, rhubarb and changja according to the present invention have pore contraction effect, anti-inflammatory effect and anti-acne effect to test the application effect of cosmetics for improving oily skin, respectively. It shows a higher effect than a single herbal extract of can be used to improve the oily skin even with a small amount.

Formulation Example 1 and Formulation Comparative Example 1

Oily skin improvement lotion containing the extract of rhubarb, red ginseng, yellow lotus and changja according to the extraction example 15 was prepared with the ingredients and contents of the following Table 9. First, components 2 to 4 were added to component 1, and a mixture in which components 6 to 7 were dissolved in component 5 and component 8 was added and mixed in turn.

number Ingredient Name (Unit: Weight%) Formulation Example 1 Formulation Comparative Example 1 One  Purified water Remaining amount Remaining amount 2  Butylene Glycol 3.0 3.0 3  glycerin 1.0 1.0 4  Fiji-1500 0.5 0.5 5  ethanol 10.0 10.0 6  Polysorbate 80 0.2 0.2 7  antiseptic a very small amount a very small amount 8  Herbal Medicine Extract According to Extraction Example 15 0.5 -

Formulation Example 2 and Formulation Comparative Example 2

An emulsion for improving oily skin containing extracts of rhubarb, red ginseng, yellow lotus and changja according to the extraction example 15 was prepared using the ingredients and contents of Table 10 below. First, components 1 to 7 are dissolved by heating at a temperature of 70 ° C., and then components 8 to 11 are dispersed in component 12 and emulsified by heating to 70 ° C. Thereafter, the emulsified product was neutralized with component 13, cooled to a temperature of 56 ° C, and component 14 was added thereto, stirred, and cooled to room temperature.

Formulation Comparative Example 2 for Formulation Example 2 was prepared in the same manner as in Formulation Example 2 with the remaining components except for the extract of rhubarb, ginseng, rhubarb, and Chang-za which is the 14th component.

number Ingredient Name (Unit: Weight%) Formulation Example 2 Formulation Comparative Example 2 One  Cetearyl Alcohol 1.2 1.2 2  Glyceryl Stearate 0.4 0.4 3  Polysorbate 60 0.9 0.9 4  Sorbitan sesquioleate 0.3 0.3 5  Liquid paraffin 2.0 2.0 6  Squalane 3.0 3.0 7  Apricot kernel oil 2.0 2.0 8  Butylene Glycol 4.0 4.0 9  Carbomer 0.12 0.12 10  Xanthan Gum 0.02 0.02 11  antiseptic a very small amount a very small amount 12  Purified water Remaining amount Remaining amount 13  Arginine 0.12 0.12 14  Herbal Medicine Extract According to Extraction Example 15 1.0 -

Formulation Example 3 and Formulation Comparative Example 3

The oily skin improvement pack containing the extract of rhubarb, red ginseng, yellow lotus and changja according to the extraction example 15 was prepared with the ingredients and contents of Table 11 below. First, prepare a mixture by dissolving or dispersing components 2 to 5 in component 1, and then dispersing components 6 to 7 in a fractionated component 1 at a temperature of 75 ° C. and adding it to the mixture of components 1 described above. Dispersed. The composition was cooled to a temperature of 56 ° C., and then prepared by stirring and adding components 8 to 11 and 12 which were previously solubilized and cooled to room temperature.

Formulation Comparative Example 3 for Formulation Example 3 was prepared in the same manner as in Formulation Example 3 with the remaining ingredients except extract No. 12, rhubarb, ginseng, rhubarb and Chang Changja.

number Ingredient Name (Unit: Weight%) Formulation Example 3 Formulation Comparative Example 3 One  Purified water Remaining amount Remaining amount 2  Citric acid 0.05 0.05 3  Butylene Glycol 5.0 5.0 4  Serisite 15.0 15.0 5  glycerin 5.0 5.0 6  Polyvinyl alcohol 12.0 12.0 7  Polyvinylpyrrolidone 4.0 4.0 8  ethanol 7.0 7.0 9  Rose Hip Oil 0.1 0.1 10  Polysorbate 60 0.5 0.5 11  antiseptic a very small amount a very small amount 12  Herbal Medicine Extract According to Extraction Example 15 1.5 -

Acne improvement effect and skin irritation sensory test

In order to evaluate the acne improvement effect and skin irritation including the sebum inhibitory effect on the cosmetic composition for improving oily skin according to the present invention, using the emulsion for improving oily skin prepared in Formulation Example 2 and Comparative Formula 2 The sensory test was carried out.

The cosmetic composition of Formulation Example 2 and Comparative Comparative Example 2 was used for three months according to a general method of use in 20 women in their 20s to 30s with acne to evaluate skin irritation. Regarding the acne improvement effect items including skin pore contraction effect, the improvement effect of the emulsion of Formulation Example 2 was relatively evaluated based on the emulsion of Formulation Comparative Example 2. The sensory evaluation was performed based on the five-point criteria of very good (5 points), good (3 points), moderate (0 points), bad (-3 points), and very bad (-5 points). It is shown in Table 12 below. In Table 12, the skin irritation item indicates the degree of no skin irritation.

The skin irritation, which is an evaluation item, is an evaluation of the itch, itching, and erythema of the skin, and the improvement effect on the oily skin is an evaluation of the degree of sebum secretion and acne reduction.

number Skin irritation Oily skin improvement effect Formulation Example 2 Formulation Comparative Example 2 One 5 5 5 2 4 5 4 3 5 5 5 4 4 4 4 5 5 5 4 6 4 5 4 7 5 5 5 8 4 4 4 9 5 5 5 10 5 5 5 11 4 4 4 12 5 5 5 13 4 4 4 14 5 5 5 15 4 4 5 16 4 5 4 17 5 5 5 18 4 4 4 19 5 5 5 20 4 5 5 Average 4.43 4.62 4.55

As shown in Table 12, the skin irritation evaluation score for the cosmetic composition of the formulation of Example 2 according to the present invention was evaluated very well at 4.43, and the skin irritation degree was low as in Comparative Formula 2, so the skin safety was excellent. Could confirm. In addition, the relative oily skin improvement effect of the cosmetic composition of Formulation Example 2 compared to Formulation Comparative Example 2 was 4.55 points, it was found that the degree of improvement is very excellent.

Extracts of rhubarb, ginseng, rhubarb and changja according to the present invention have an excellent oily skin improvement effect by showing an excellent effect in pore contraction effect, anti-inflammatory effect and anti-acne effect that inhibits excess sebum associated with oily skin. In addition, the cosmetic composition for improving oily skin containing such extracts of rhubarb, red ginseng, rhubarb and changja is not only safe for the skin, but also has an effect of reducing sebum secretion on acne skin and reducing acne.

Claims (9)

A cosmetic composition for improving oily skin having pore contraction, anti-inflammatory and anti-acne bacterium effects, which comprises extracts of rhubarb, red ginseng, rhubarb and changja. delete According to claim 1, wherein the content of each of the extract of rhubarb, red ginseng, rhubarb and changja is oily skin improvement cosmetic composition, characterized in that 10 to 50% by weight relative to the total weight of the extract. According to claim 1, wherein the content of the extract is a cosmetic composition for improving oily skin, characterized in that 0.001 to 10% by weight relative to the total weight of the cosmetic composition. According to claim 1, wherein the cosmetic composition is a cosmetic composition for improving oily skin, characterized in that any one selected from the group consisting of cosmetics, creams, face-wash cosmetics, packs, foundations and makeup bases. Preparing a mixture of rhubarb, red ginseng, rhubarb and changja; And adding an extraction solvent selected from the group consisting of water, ethanol and butylene glycol to the mixture, and extracting an active ingredient. The method of claim 6, wherein the contents of rhubarb, ginseng, rhubarb and changja in the preparation of the mixture are 10 to 50% by weight based on the total weight of the mixture. The method of claim 6, wherein the extracting is a method for preparing an oily skin improvement extract, characterized in that the extract is deposited for 1 to 15 days at a temperature of 5 to 37 ℃. The method of claim 6, wherein the extracting is a method for producing an oily skin improvement extract, characterized in that the extraction for 1 to 20 hours at a temperature of 50 to 95 ℃.