CN105087189A - Plant anti-bacterial compound germicidal soap and preparation method thereof - Google Patents

Plant anti-bacterial compound germicidal soap and preparation method thereof Download PDF

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Publication number
CN105087189A
CN105087189A CN201510534945.6A CN201510534945A CN105087189A CN 105087189 A CN105087189 A CN 105087189A CN 201510534945 A CN201510534945 A CN 201510534945A CN 105087189 A CN105087189 A CN 105087189A
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soap
extract
oil
tea tree
lanolin
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CN105087189B (en
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滕利荣
王娟
滕乐生
孟庆繁
刘艳
程瑛琨
王贞佐
谢晶
逯家辉
刘龙图
胡爽
李剑光
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Jilin University
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Jilin University
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Abstract

The invention relates to a plant anti-bacterial compound germicidal soap and a preparation method thereof. The plant anti-bacterial compound germicidal soap comprises the following main ingredients: extracts of rhizoma gastrodiae, lavender essential oil, tea tree essential oil, artemisia vulgaris oil, scutellaria extracts, cordyceps sinensis extracts and lanolin, has capabilities such as antisepsis and anti-inflammation, skin whitening and acne treatment, has effects of well cleaning skin and supplementing skin moisture, repairing injured cells and resisting cell injury caused by ultraviolet rays, is safe, does not have side effects, and is suitable to be used for a long time.

Description

A kind of plants antimicrobial compound germicidal soap and preparation method thereof
Technical field
The invention belongs to daily washing product technical field, be specifically related to a kind of plants antimicrobial compound germicidal soap and preparation method thereof.
Background technology
In recent years, science and technology is brought increasing " side effect " to people's life now, and household chemicals industry is particularly outstanding, such as: certain brand " present time " in 2005; 2006 from being found containing forbidding composition in certain branding cosmetic; Johson & Johnson exaggerates sunscreen products and has provide protection and the event that misguides the consumer.Increasing people pursues individual character consumption, in life, thirst for back to nature, and the natural disinfection soap product containing multiple natural skin care composition is paid close attention to because meet people widely for the demand of personalization, natural mode.
Acne is being commonly called as of acne, be called again " comedo ", " acne ", be due to hair follicle or sebiferous gland block, inflammation and the common skin diseases that causes, in pubescence, body hormone secretion increases, and impelling skin oil and fat to secrete increases, and causes skin surface grease and bacterial adhesion, cause comedo incidence to increase, increase teenager's health and psychological burden.The present invention relates to germicidal soap and add the natural antibacterial anti-inflammation components such as Rhizoma Gastrodiae extract, Herba Lysimachiae foenumgraeci quintessence oil, tea tree ethereal oil, P-Cymene, Radix Scutellariae extract, Cordyceps extract, lanolin, effective adjustment skin fat secretion, pore refining, supplements moisture needed for skin, makes skin more smooth.
Summary of the invention
The present invention aims to provide a kind of plants antimicrobial compound germicidal soap, containing the multiple Chinese medicine material with remarkable anti-microbial activity, while ensureing good clean and supplementary moisture of skin effect, can regulation of skin surface grease balanced, antisepsis and anti-inflammation, reduces the generation of comedo, eliminates acne print simultaneously, safety has no side effect, and is applicable to life-time service.
Present invention also offers a kind of preparation method of plants antimicrobial compound germicidal soap, be applicable to suitability for industrialized production.
A kind of plants antimicrobial compound germicidal soap of the present invention, is characterized in that the raw material primarily of following weight part is made:
Rhizoma Gastrodiae extract 0.1 ~ 2 part, Herba Lysimachiae foenumgraeci quintessence oil 0.02 ~ 0.2 part, tea tree ethereal oil 0.02 ~ 0.2 part, P-Cymene 0.01 ~ 0.1 part, Radix Scutellariae extract 0.1 ~ 2 part, Cordyceps extract 0.1 ~ 2 part, 0.1 ~ 0.5 part, lanolin, shea butter 1 ~ 10 part, Hawaii macadamia nut oil 1 ~ 10 part, vitamin-E 0.1 ~ 1 part, aloe dry powder 1 ~ 10 part
The preparation method of plants antimicrobial compound germicidal soap of the present invention, comprises the following steps:
60 ~ 100 DEG C of heating soap bases, stirring makes it melt completely, Rhizoma Gastrodiae extract, Herba Lysimachiae foenumgraeci quintessence oil, tea tree ethereal oil, P-Cymene, Radix Scutellariae extract, Cordyceps extract, lanolin, shea butter, Hawaii macadamia nut oil, vitamin-E, aloe dry powder is added in proportion in the soap base after thawing, stir 10 ~ 15 minutes, pour in ready mould, after room temperature places cooling, the demoulding, obtains germicidal soap finished product.
Fang Xie: Herba Lysimachiae foenumgraeci quintessence oil has clearing heat and detoxicating, cleaning skin, control oil content, freckle removing and whitening isoreactivity, can eye haustra-dsipelling black eye, promote damaged tissue regeneration; Tea tree ethereal oil has bactericidal antiphlogistic, convergence pore; P-Cymene has bactericidal haemostatic, antiallergic activity; Rhizoma Gastrodiae is warm in nature, flat, is used for the treatment of headache dizzy, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus; The root of large-flowered skullcap is bitter, cold, and for damp-warm syndrome, heat temperature evil of vomitting uncomfortable in chest, damp and hot ruffian is full, and rush down dysentery, jaundice, cough due to lung-heat, high hot polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, threatened abortion; Vitamin-E has good anti-oxidant activity; Aloe dry powder can improve immunizing power, beautifying whitening skin, crease-resistant isoreactivity.The present invention relates to handmade soap with Rhizoma Gastrodiae extract, Herba Lysimachiae foenumgraeci quintessence oil for monarch drug in a prescription, with tea tree ethereal oil, P-Cymene, Radix Scutellariae extract for ministerial drug, assistant is with Cordyceps extract, lanolin, vitamin-E, aloe dry powder composition, prepare, all medicines are worked in coordination with, and ensure handmade soap antisepsis and anti-inflammation, whitening, anti-acne effect.
Positively effect of the present invention is: germicidal soap involved in prescription contains the multiple skin care ingredient such as Herba Lysimachiae foenumgraeci quintessence oil, tea tree ethereal oil, and remain the multiple nutritional components such as Chinese caterpillar fungus adenosine, Chinese medical extract, vitamin-E, aloe dry powder to greatest extent, make product while playing cleaning action, have good antisepsis and anti-inflammation, whitening, anti-acne effect.
Embodiment
In order to technology contents of the present invention can be understood better, describe the present invention below by concrete case study on implementation.
embodiment 1
60 DEG C of heating 100g soap bases, stirring makes it melt completely, 0.02g Herba Lysimachiae foenumgraeci quintessence oil, 0.02g tea tree ethereal oil, 0.01g P-Cymene, 0.1g Radix Scutellariae extract, 0.1g Rhizoma Gastrodiae extract, 0.1g Cordyceps extract, 0.1g lanolin, 3g shea butter, 7g Hawaii macadamia nut oil, 0.3g vitamin-E, 2g aloe dry powder is added in the soap base after thawing, stir 15 minutes, pour in ready mould, after room temperature places cooling, the demoulding, obtains germicidal soap finished product.
embodiment 2
80 DEG C of heating 100g soap bases, stirring makes it melt completely, 0.05g Herba Lysimachiae foenumgraeci quintessence oil, 0.05g tea tree ethereal oil, 0.02g P-Cymene, 0.5g Radix Scutellariae extract, 0.5g Rhizoma Gastrodiae extract, 0.5g Cordyceps extract, 0.5g lanolin, 5g shea butter, 5g Hawaii macadamia nut oil, 0.5g vitamin-E, 3g aloe dry powder is added in the soap base after thawing, stir 15 minutes, pour in ready mould, after room temperature places cooling, the demoulding, obtains germicidal soap finished product.
case study on implementation 3
100 DEG C of heating 100g soap bases, stirring makes it melt completely, 0.1g Herba Lysimachiae foenumgraeci quintessence oil, 0.02g tea tree ethereal oil, 0.05g P-Cymene, 0.5g Radix Scutellariae extract, 1.0g Rhizoma Gastrodiae extract, 1.0g Cordyceps extract, 0.5g lanolin, 3g shea butter, 3g Hawaii macadamia nut oil, 0.3g vitamin-E, 5g aloe dry powder is added in the soap base after thawing, stir 10 minutes, pour in ready mould, after room temperature places cooling, the demoulding, obtains germicidal soap finished product.
case study on implementation 4
60 DEG C of heating 100g soap bases, stirring makes it melt completely, 0.05g Herba Lysimachiae foenumgraeci quintessence oil, 0.1g tea tree ethereal oil, 0.03g P-Cymene, 0.5g Radix Scutellariae extract, 0.5g Rhizoma Gastrodiae extract, 2g Cordyceps extract, 0.2g lanolin, 4g shea butter, 4g Hawaii macadamia nut oil, 0.2g vitamin-E, 3g aloe dry powder is added in the soap base after thawing, stir 10 minutes, pour in ready mould, after room temperature places cooling, the demoulding, obtains germicidal soap finished product.
case study on implementation 5
100 DEG C of heating 100g soap bases, stirring makes it melt completely, 0.08g Herba Lysimachiae foenumgraeci quintessence oil, 0.14g tea tree ethereal oil, 0.02g P-Cymene, 1.5g Radix Scutellariae extract, 0.8g Rhizoma Gastrodiae extract, 1.5g Cordyceps extract, 0.2g lanolin, 8g shea butter, 6g Hawaii macadamia nut oil, 0.5g vitamin-E, 1g aloe dry powder is added in the soap base after thawing, stir 10 minutes, pour in ready mould, after room temperature places cooling, the demoulding, obtains germicidal soap finished product.
positively effect of the present invention is shown by following test example:
pH value detects
Take each 1.0g(of embodiment 1 ~ embodiment 5 and be accurate to 0.01g), add ultrapure water, heating makes it melt evenly, is settled to 10ml, measures its pH value after cooling, measurement result shows, case study on implementation 1pH value is 8.01, and case study on implementation 2pH value is 8.32, and case study on implementation 3pH value is 7.89, case study on implementation 4pH value is 8.21, and case study on implementation 5pH value is 8.08.
the present invention always free caustic alkali detects
Carry out total free alkali in sample according to Q/T2623.1-2003 regulation to detect, experimental result shows, and 5 kinds of case study on implementation dissolve with ethanol things all can not make the aobvious pink of phenolphthalein indicator, proves to detect without free caustic alkali in its dissolve with ethanol thing, prove that secure sample is good, to no skin irritation.
bacteriostatic activity of the present invention detects.
According to Ministry of Health of the People's Republic of China " disinfection technology standard " " (version in 2002) regulation carry out 5 kinds of case study on implementation to intestinal bacteria (ATCC25922), golden staphylococci (ATCC6538), Candida albicans (ATCC10231) bacteriostatic activity detect.
Sample Action time To intestinal bacteria (ATCC25922) bacteriostasis rate To golden staphylococci (ATCC 6538) bacteriostasis rate To Candida albicans (ATCC 10231) bacteriostasis rate
Case study on implementation 1 2min 90.67% 92.12% 90.96%
Case study on implementation 2 2min 86.76% 90.33% 91.21%
Case study on implementation 3 2min 89.24% 91.42% 90.32%
Case study on implementation 4 2min 91.77% 94.32% 91.01%
Case study on implementation 5 2min 93.04% 96.45% 91.11%
Manual soap base 2min 50.12% 48.77% 51.52%
2% Rhizoma Gastrodiae extract 2min 67.71% 70.12% 69.55%
2% Radix Scutellariae extract 2min 81.01% 83.11% 80.10%
0.2% tea tree ethereal oil 2min 72.32% 75.11% 70.82%
0.2% Herba Lysimachiae foenumgraeci quintessence oil 2min 60.12% 62.23% 62.55%
0.1% P-Cymene 2min 50.11% 48.72% 50.12%
As can be seen from experimental result, in 5 groups of case study on implementation after germicidal soap effect 2min, all can more than 85% be reached to the inhibiting rate of intestinal bacteria (ATCC25922), more than 90% is reached to golden staphylococci (ATCC6538) bacteriostasis rate, more than 90% is reached to Candida albicans (ATCC10231) bacteriostasis rate, all medicines are worked in coordination with, and have stronger bacteriostatic activity.
whitening Performance Detection
Adopt biological zymetology method to detect the activity of tyrosine oxidase, tyrosine oxidase is the key enzyme forming melanocyte, and better to tyrosinase inhibitory action, whitening effect is more obvious.That therefore can carry out assess sample by the inhibiting rate of working sample to enzymic activity brightens function.
Measure by experiment,
The inhibiting rate of embodiment case 1 pair of tyrosine oxidase is 2.23%;
The inhibiting rate of case study on implementation 2 pairs of tyrosine oxidases is 4.38%;
The inhibiting rate of case study on implementation 3 pairs of tyrosine oxidases is 3.17%;
The inhibiting rate of case study on implementation 4 pairs of tyrosine oxidases is 2.98%;
The inhibiting rate of case study on implementation 5 pairs of tyrosine oxidases is 3.54%.
Conclusion: germicidal soap of the present invention has good inhibiting rate to tyrosine oxidase, proves that it has stronger whitening effect.
resisiting influenza virus of the present invention (FM1) Activity determination.
Influenza virus A-prime mouse lung adapted strain (FM1) is adopted to carry out Antiviral Effect Activity determination, by influenza infection mdck cell, observe drug on viral cytopathic effect, calculate Antiviral Effect efficient, measure neuraminic acid enzyme activity.Experimental result is as shown in the table.
Sample Sample introduction/μ g 1640 add-ons/μ L Antiviral efficient/% Neuraminic acid enzyme activity (U)
Cell controls group 0 500 --- 1.00
Virus control group 0 500 --- 2.59
Case study on implementation 1 50 450 89.72 1.08
Case study on implementation 2 50 450 86.26 1.13
Case study on implementation 3 50 450 87.15 1.21
Case study on implementation 4 50 450 88.32 1.29
Case study on implementation 5 50 450 87.92 1.17
Manual soap base 50 450 10.01% 2.55
2% Rhizoma Gastrodiae extract 50 450 15.52% 2.05
2% Radix Scutellariae extract 50 450 62.62% 1.76
0.2% tea tree ethereal oil 50 450 50.19% 1.95
0.2% Herba Lysimachiae foenumgraeci quintessence oil 50 450 50.22% 1.82
0.1% P-Cymene 50 450 46.11% 2.01
As can be seen from experimental result, all reach more than 85%, compare with virus control group at the inhibiting rate of guarantee 5 groups of case study on implementation infected by influenzas, 5 groups of case study on implementation samples obviously can reduce neuraminidase activity, and all medicines are worked in coordination with, and have significant antiviral effect
Conclusion:
Comprehensive every result can prove, germicidal soap of the present invention has well antibacterial, anti-oxidant, whitening, anti-acne effect, and it has good security, is applicable to long-term edible.

Claims (2)

1. a plants antimicrobial compound germicidal soap, is characterized in that the raw material primarily of following weight part is made:
Rhizoma Gastrodiae extract 0.1 ~ 2 part, Herba Lysimachiae foenumgraeci quintessence oil 0.02 ~ 0.2 part, tea tree ethereal oil 0.02 ~ 0.2 part, P-Cymene 0.01 ~ 0.1 part, Radix Scutellariae extract 0.1 ~ 2 part, Cordyceps extract 0.1 ~ 2 part, 0.1 ~ 1 part, lanolin, shea butter 1 ~ 10 part, Hawaii macadamia nut oil 1 ~ 10 part, vitamin-E 0.1 ~ 1 part, aloe dry powder 1 ~ 10 part.
2. the preparation method of plants antimicrobial compound germicidal soap according to claim 1, comprises the following steps:
60 ~ 100 DEG C of heating soap bases, stirring makes it melt completely, Rhizoma Gastrodiae extract, Herba Lysimachiae foenumgraeci quintessence oil, tea tree ethereal oil, P-Cymene, Radix Scutellariae extract, Cordyceps extract, lanolin, shea butter, Hawaii macadamia nut oil, vitamin-E, aloe dry powder etc. are added in proportion in the soap base after thawing, stir 10 ~ 15 minutes, pour in ready mould, after room temperature places cooling, the demoulding, obtains germicidal soap finished product.
CN201510534945.6A 2015-08-28 2015-08-28 A kind of plants antimicrobial compound germicidal soap and preparation method thereof Active CN105087189B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106591011A (en) * 2016-10-21 2017-04-26 威莱(广州)日用品有限公司 Antibacterial soap and preparation method thereof
CN107312640A (en) * 2017-07-05 2017-11-03 芜湖慧宇商贸有限公司 A kind of preparation method of the Traditional Chinese medicine laundry detergent containing Baical Skullcap root P.E
CN108203631A (en) * 2016-12-16 2018-06-26 汉义生物科技(北京)有限公司 A kind of antibacterial cleaning products and preparation method thereof
CN109456862A (en) * 2018-12-21 2019-03-12 谢时京 A kind of folium artemisiae argyi handmade soap and preparation method thereof
CN110042020A (en) * 2019-05-07 2019-07-23 海南大学 A kind of antibacterial handmade soap of essential oil and preparation method thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111184757A (en) * 2020-03-20 2020-05-22 蒋成聚 Plant folium artemisiae argyi extract and silver ion compound bactericide and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN102994281A (en) * 2011-09-16 2013-03-27 沈新荣 Essential oil soap and making method thereof
CN103789109A (en) * 2014-03-06 2014-05-14 卫笑心 Skin cleaning soap and manufacturing method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102994281A (en) * 2011-09-16 2013-03-27 沈新荣 Essential oil soap and making method thereof
CN103789109A (en) * 2014-03-06 2014-05-14 卫笑心 Skin cleaning soap and manufacturing method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106591011A (en) * 2016-10-21 2017-04-26 威莱(广州)日用品有限公司 Antibacterial soap and preparation method thereof
CN108203631A (en) * 2016-12-16 2018-06-26 汉义生物科技(北京)有限公司 A kind of antibacterial cleaning products and preparation method thereof
CN107312640A (en) * 2017-07-05 2017-11-03 芜湖慧宇商贸有限公司 A kind of preparation method of the Traditional Chinese medicine laundry detergent containing Baical Skullcap root P.E
CN109456862A (en) * 2018-12-21 2019-03-12 谢时京 A kind of folium artemisiae argyi handmade soap and preparation method thereof
CN110042020A (en) * 2019-05-07 2019-07-23 海南大学 A kind of antibacterial handmade soap of essential oil and preparation method thereof

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