CN105087189B - A kind of plants antimicrobial compound germicidal soap and preparation method thereof - Google Patents
A kind of plants antimicrobial compound germicidal soap and preparation method thereof Download PDFInfo
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- CN105087189B CN105087189B CN201510534945.6A CN201510534945A CN105087189B CN 105087189 B CN105087189 B CN 105087189B CN 201510534945 A CN201510534945 A CN 201510534945A CN 105087189 B CN105087189 B CN 105087189B
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Abstract
The present invention relates to a kind of plants antimicrobial compound germicidal soap and preparation method thereof, it is made of main components such as Rhizoma Gastrodiae extract, Lavender, tea tree ethereal oil, P-Cymene, Baical Skullcap root P.E, Cordyceps, lanolin, with antibacterial anti-inflammatory, whitening, anti-acne isoreactivity, there is good cleaning and supplement moisture of skin effect at the same time, repair damaged cell, UV-induced cellular damage effect is resisted, and it is safe without side-effects, it is adapted to long-time service.
Description
Technical field
The invention belongs to daily washing product technical field, and in particular to a kind of plants antimicrobial compound germicidal soap and its preparation
Method.
Background technology
In recent years, science and technology is brought more and more " side effects " to people's life now, and household chemicals industry is particularly prominent
Go out, such as：Certain brand " present time " in 2005；Come within 2006 in certain brand cosmetics and found containing disabling component；
Johson ＆ Johnson exaggerates sunscreen products with protective effect and the event that misguides the consumer.More and more people pursue individual character consumption, in life
Back to nature is thirsted in work, the natural disinfection soap product containing a variety of natural skin care components is because meet people for individual character
Change, the demand of natural mode and widely paid close attention to.
Acne is being commonly called as acne, is called and does " whelk ", " acne ", be due to hair follicle or sebum adenemphraxis, inflammation and draw
The common skin diseases risen, in puberty, the increase of body hormone secretion, promotes skin oil and fat secretion increase, causes skin table
Face grease and bacterium attachment, cause the increase of whelk incidence, increase teenager's body and psychological burden.The present invention relates to sterilization
Soap addition Rhizoma Gastrodiae extract, Lavender, tea tree ethereal oil, P-Cymene, Baical Skullcap root P.E, Cordyceps, lanolin etc.
Natural antibacterial anti-inflammation components, effectively adjust skin fat secretion, pore refining, moisture needed for supplement skin, makes skin more light
It is sliding.
The content of the invention
The present invention is intended to provide a kind of plants antimicrobial compound germicidal soap, contains a variety of middle medicines with notable antibacterial activity
Matter, while good cleaning and supplement moisture of skin effect is ensured, can adjust the equilibrium of skin surface grease, antibacterial disappears
Inflammation, reduces the generation of whelk, while eliminates acne print, and safety is without side-effects, is adapted to long-time service.
Present invention also offers a kind of preparation method of plants antimicrobial compound germicidal soap, suitable for industrialized production.
A kind of plants antimicrobial compound germicidal soap of the present invention, it is characterised in that mainly by the raw material system of following parts by weight
Into：
0.1 ~ 2 part of Rhizoma Gastrodiae extract, 0.02 ~ 0.2 part of Lavender, 0.02 ~ 0.2 part of tea tree ethereal oil, P-Cymene
0.01 ~ 0.1 part, 0.1 ~ 2 part of Baical Skullcap root P.E, 0.1 ~ 2 part of Cordyceps, 0.1 ~ 0.5 part of lanolin, shea butter 1
~ 10 parts, 1 ~ 10 part of Hawaii macadamia nut oil, 0.1 ~ 1 part of vitamin E, 1 ~ 10 part of aloe dry powder
The preparation method of plants antimicrobial compound germicidal soap of the present invention, comprises the following steps：
60~100 DEG C of heating soap bases, stirring make it melt completely, and rhizoma Gastrodiae extraction is proportionally added into the soap base after thawing
Thing, Lavender, tea tree ethereal oil, P-Cymene, Baical Skullcap root P.E, Cordyceps, lanolin, shea butter, Hawaii
Macadamia nut oil, vitamin E, aloe dry powder, stir 10~15 minutes, pour into ready mould, after room temperature places cooling, take off
Mould, up to germicidal soap finished product.
Fang Xie：Lavender has clearing heat and detoxicating, cleaning skin, control oil, freckle removing and whitening isoreactivity, can dispel
Pouch livid ring around eye, promote regeneration of damaged tissue；Tea tree ethereal oil has bactericidal antiphlogistic, convergence pore；P-Cymene stops with sterilization
Blood, antiallergic activity；Rhizoma Gastrodiae is warm-natured, flat, for treating dizziness of having a headache, extremity numbness, child convulsion, epilepsy clonus, lockjaw；
Radix scutellariae is bitter, cold, is spat for damp-warm syndrome, heat temperature chest tightness and emesis, damp and hot feeling of fullness, rush down dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head
Nosebleed, carbuncle sore tumefacting virus, fetal irritability；Vitamin E has good antioxidation activity；Aloe dry powder can improve immunity, beauty
Skin whitening, crease-resistant isoreactivity.The present invention relates to handmade soap using Rhizoma Gastrodiae extract, Lavender as monarch drug in a prescription, with tea tree ethereal oil,
P-Cymene, Baical Skullcap root P.E are ministerial drug, help and are obtained with Cordyceps, lanolin, vitamin E, aloe dry powder component, preparation
, all medicine collaborations, ensure handmade soap antibacterial anti-inflammatory, whitening, anti-acne effect.
The positive effect of the present invention is：It is more to contain Lavender, tea tree ethereal oil etc. for involved germicidal soap in prescription
Kind of skin care ingredient, and remain to greatest extent a variety of nutrition such as cordyceps sinensis adenosine, Chinese medical extract, vitamin E, aloe dry powder into
Point, make product while cleaning action is played with good antibacterial anti-inflammatory, whitening, anti-acne.
Embodiment
In order to be best understood from the technology contents of the present invention, the present invention is carried out below by specific implementation case detailed
Thin description.
Embodiment 1
60 DEG C of heating 100g soap bases, stirring make it melt completely, and 0.02g lavenders essence is added into the soap base after thawing
Oil, 0.02g tea tree ethereal oils, 0.01g P-Cymenes, 0.1g Baical Skullcap root P.Es, 0.1g Rhizoma Gastrodiae extracts, 0.1g Cordyceps,
0.1g lanolin, 3g shea butters, 7g Hawaii macadamia nut oil, 0.3g vitamin Es, 2g aloe dry powders, stir 15 minutes, pour into pre-
In the mould got ready, after room temperature places cooling, the demoulding, up to germicidal soap finished product.
Embodiment 2
80 DEG C of heating 100g soap bases, stirring make it melt completely, and 0.05g lavenders essence is added into the soap base after thawing
Oil, 0.05g tea tree ethereal oils, 0.02g P-Cymenes, 0.5g Baical Skullcap root P.Es, 0.5g Rhizoma Gastrodiae extracts, 0.5g Cordyceps,
0.5g lanolin, 5g shea butters, 5g Hawaii macadamia nut oil, 0.5g vitamin Es, 3g aloe dry powders, stir 15 minutes, pour into pre-
In the mould got ready, after room temperature places cooling, the demoulding, up to germicidal soap finished product.
Case study on implementation 3
100 DEG C of heating 100g soap bases, stirring make it melt completely, and 0.1g lavenders essence is added into the soap base after thawing
Oil, 0.02g tea tree ethereal oils, 0.05g P-Cymenes, 0.5g Baical Skullcap root P.Es, 1.0g Rhizoma Gastrodiae extracts, 1.0g Cordyceps,
0.5g lanolin, 3g shea butters, 3g Hawaii macadamia nut oil, 0.3g vitamin Es, 5g aloe dry powders, stir 10 minutes, pour into pre-
In the mould got ready, after room temperature places cooling, the demoulding, up to germicidal soap finished product.
Case study on implementation 4
60 DEG C of heating 100g soap bases, stirring make it melt completely, and 0.05g lavenders essence is added into the soap base after thawing
Oil, 0.1g tea tree ethereal oils, 0.03g P-Cymenes, 0.5g Baical Skullcap root P.Es, 0.5g Rhizoma Gastrodiae extracts, 2g Cordyceps, 0.2g
Lanolin, 4g shea butters, 4g Hawaii macadamia nut oil, 0.2g vitamin Es, 3g aloe dry powders, stir 10 minutes, pour into ready
Mould in, room temperature place cooling after, the demoulding, up to germicidal soap finished product.
Case study on implementation 5
100 DEG C of heating 100g soap bases, stirring make it melt completely, and 0.08g lavenders essence is added into the soap base after thawing
Oil, 0.14g tea tree ethereal oils, 0.02g P-Cymenes, 1.5g Baical Skullcap root P.Es, 0.8g Rhizoma Gastrodiae extracts, 1.5g Cordyceps,
0.2g lanolin, 8g shea butters, 6g Hawaii macadamia nut oil, 0.5g vitamin Es, 1g aloe dry powders, stir 10 minutes, pour into pre-
In the mould got ready, after room temperature places cooling, the demoulding, up to germicidal soap finished product.
The positive effect of the present invention is shown by tests below example：
PH value detects
Weigh 1 ~ embodiment of embodiment, 5 each 1.0g（It is accurate to 0.01g）, ultra-pure water is added, it is uniform that heating melts it, cold
But 10ml is settled to afterwards, measures its pH value, and measurement result is shown, 1 pH value of case study on implementation is 8.01, and 2 pH value of case study on implementation is
8.32,3 pH value of case study on implementation is 7.89, and 4 pH value of case study on implementation is 8.21, and 5 pH value of case study on implementation is 8.08.
Always free caustic alkali detection of the invention
Provide to carry out total free alkali detection, experimental result in sample according to Q/T2623.1-2003 to show, 5 kinds of case study on implementation
Ethanol dissolved matter cannot make phenolphthalein indicator show pink, it was demonstrated that be detected in its ethanol dissolved matter without free caustic alkali, it was demonstrated that
Secure sample is good, to no skin irritation.
Bacteriostatic activity detection of the present invention.
According to Ministry of Health of the People's Republic of China《Disinfection technology standard》》（Version in 2002）Regulation carries out 5 kinds of case study on implementation
To Escherichia coli（ATCC25922）, golden staphylococci（ATCC 6538）, Candida albicans（ATCC 10231）Bacteriostatic activity is examined
Survey.
| Sample | Effect Time | To Escherichia coli （ATCC25922）Bacteriostasis rate | To golden staphylococci（ATCC 6538）Bacteriostasis rate | To Candida albicans（ATCC 10231）Bacteriostasis rate |
| Case study on implementation 1 | 2min | 90.67% | 92.12% | 90.96% |
| Case study on implementation 2 | 2min | 86.76% | 90.33% | 91.21% |
| Case study on implementation 3 | 2min | 89.24% | 91.42% | 90.32% |
| Case study on implementation 4 | 2min | 91.77% | 94.32% | 91.01% |
| Case study on implementation 5 | 2min | 93.04% | 96.45% | 91.11% |
| Manual soap base | 2min | 50.12% | 48.77% | 51.52% |
| 2% rhizoma Gastrodiae carries Take thing | 2min | 67.71% | 70.12% | 69.55% |
| 2% radix scutellariae carries Take thing | 2min | 81.01% | 83.11% | 80.10% |
| 0.2% tea tree Essential oil | 2min | 72.32% | 75.11% | 70.82% |
| 0.2% smokes clothing Careless essential oil | 2min | 60.12% | 62.23% | 62.55% |
| 0.1% folium artemisiae argyi Essential oil | 2min | 50.11% | 48.72% | 50.12% |
After germicidal soap effect 2min in 5 groups of case study on implementation it can be seen from experimental result, to Escherichia coli
（ATCC25922）Inhibiting rate up to more than 85%, to golden staphylococci（ATCC 6538）Bacteriostasis rate is up to more than 90%, dialogue
Color candida albicans（ATCC 10231）For bacteriostasis rate up to more than 90%, all medicine collaborations, have stronger bacteriostatic activity.
Whitening performance detection
Using the activity of biological zymetology method detection tyrosinase, tyrosinase is the key enzyme to form melanocyte, to tyrosine
Enzyme inhibition is better, and whitening effect is more obvious.Therefore sample can be evaluated to the inhibiting rate of enzymatic activity by determination sample
Brighten function.
It is determined by experiment,
Embodiment case 1 is 2.23% to the inhibiting rate of tyrosinase；
Case study on implementation 2 is 4.38% to the inhibiting rate of tyrosinase；
Case study on implementation 3 is 3.17% to the inhibiting rate of tyrosinase；
Case study on implementation 4 is 2.98% to the inhibiting rate of tyrosinase；
Case study on implementation 5 is 3.54% to the inhibiting rate of tyrosinase.
Conclusion：Germicidal soap of the present invention has good inhibiting rate to tyrosinase, it was demonstrated that it is with stronger whitening effect.
Resisiting influenza virus of the present invention（FM1）Activity determination.
Antiviral Effect Activity determination is carried out using influenza virus A-prime mouse lung adapted strain (FM1), passes through influenza disease
Poison infection mdck cell, observation medicine act on pathological changes caused by virus, and calculating Antiviral Effect is efficient, measures neuraminic acid
Enzyme activity.The experimental results are shown inthe following table.
| Sample | Sample introduction/μ g | 1640 additions/μ L | Antiviral effective percentage/% | Neuraminic acid enzyme activity（U） |
| Cell controls group | 0 | 500 | --- | 1.00 |
| Virus control group | 0 | 500 | --- | 2.59 |
| Case study on implementation 1 | 50 | 450 | 89.72 | 1.08 |
| Case study on implementation 2 | 50 | 450 | 86.26 | 1.13 |
| Case study on implementation 3 | 50 | 450 | 87.15 | 1.21 |
| Case study on implementation 4 | 50 | 450 | 88.32 | 1.29 |
| Case study on implementation 5 | 50 | 450 | 87.92 | 1.17 |
| Manual soap base | 50 | 450 | 10.01% | 2.55 |
| 2% Rhizoma Gastrodiae extract | 50 | 450 | 15.52% | 2.05 |
| 2% Baical Skullcap root P.E | 50 | 450 | 62.62% | 1.76 |
| 0.2% tea tree ethereal oil | 50 | 450 | 50.19% | 1.95 |
| 0.2% Lavender | 50 | 450 | 50.22% | 1.82 |
| 0.1% P-Cymene | 50 | 450 | 46.11% | 2.01 |
Ensureing the inhibiting rates of 5 groups of case study on implementation infected by influenza up to more than 85% it can be seen from experimental result, with
Virus control group compares, and 5 groups of case study on implementation samples can substantially reduce neuraminidase activity, and all medicine collaborations, have significant anti-
Virus effectiveness
Conclusion：
Comprehensive items result it can be proved that germicidal soap of the present invention with good antibacterial, anti-oxidant, whitening, anti-acne effect,
It is adapted to long-term consumption with good security.
Claims (1)
1. a kind of plants antimicrobial compound germicidal soap, it is characterised in that be mainly made of the raw material of following parts by weight：
0.1 ~ 2 part of Rhizoma Gastrodiae extract, 0.02 ~ 0.2 part of Lavender, 0.02 ~ 0.2 part of tea tree ethereal oil, P-Cymene 0.01
~ 0.1 part, 0.1 ~ 2 part of Baical Skullcap root P.E, 0.1 ~ 2 part of Cordyceps, 0.1 ~ 1 part of lanolin, 1 ~ 10 part of shea butter,
1 ~ 10 part of Hawaii macadamia nut oil, 0.1 ~ 1 part of vitamin E, 1 ~ 10 part of aloe dry powder；
The preparation method of above-mentioned plants antimicrobial compound germicidal soap, comprises the following steps：
60~100 DEG C heating soap bases, stirring it is melted completely, be proportionally added into the soap base after thawing Rhizoma Gastrodiae extract,
Lavender, tea tree ethereal oil, P-Cymene, Baical Skullcap root P.E, Cordyceps, lanolin, shea butter, Hawaii nut
Oil, vitamin E, aloe dry powder, stir 10~15 minutes, pour into ready mould, after room temperature places cooling, the demoulding, i.e.,
Obtain germicidal soap finished product.
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| CN111184757A (en) * | 2020-03-20 | 2020-05-22 | 蒋成聚 | Plant folium artemisiae argyi extract and silver ion compound bactericide and preparation method thereof |
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| CN106591011B (en) * | 2016-10-21 | 2018-03-27 | 威莱(广州)日用品有限公司 | A kind of antibacterial soap and preparation method thereof |
| CN108203631A (en) * | 2016-12-16 | 2018-06-26 | 汉义生物科技（北京）有限公司 | A kind of antibacterial cleaning products and preparation method thereof |
| CN107312640A (en) * | 2017-07-05 | 2017-11-03 | 芜湖慧宇商贸有限公司 | A kind of preparation method of the Traditional Chinese medicine laundry detergent containing Baical Skullcap root P.E |
| CN109456862A (en) * | 2018-12-21 | 2019-03-12 | 谢时京 | A kind of folium artemisiae argyi handmade soap and preparation method thereof |
| CN110042020B (en) * | 2019-05-07 | 2021-12-14 | 海南大学 | Essential oil antibacterial handmade soap and preparation method thereof |
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| CN102994281A (en) * | 2011-09-16 | 2013-03-27 | 沈新荣 | Essential oil soap and making method thereof |
| CN103789109B (en) * | 2014-03-06 | 2015-12-02 | 卫笑心 | A kind of skin clean soap and manufacture method thereof |
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| CN111184757A (en) * | 2020-03-20 | 2020-05-22 | 蒋成聚 | Plant folium artemisiae argyi extract and silver ion compound bactericide and preparation method thereof |
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