CN104971161A - Application of vine tea extract in treatment of acnes - Google Patents
Application of vine tea extract in treatment of acnes Download PDFInfo
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- CN104971161A CN104971161A CN201410130834.4A CN201410130834A CN104971161A CN 104971161 A CN104971161 A CN 104971161A CN 201410130834 A CN201410130834 A CN 201410130834A CN 104971161 A CN104971161 A CN 104971161A
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- ampelopsis grossedentata
- acne
- acnes
- treatment
- extract
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Abstract
The invention relates to an application of a vine tea extract in treatment of acnes and belongs to the technical field of medicaments, health foods and daily chemical products. The vine tea extract is powder obtained by filtering, condensing and drying an aqueous extract of vine teas, and can effectively inhibit the propagation of acne propionibacterium to effectively reduce inflammatory reactions caused by the acne propionibacterium and finally cure the acnes. Meanwhile, the extract provided by the invention completely comes from natural vine teas, cannot cause adverse reactions, and can be used for a long time, so that the problems of drug resistance and side effects of antibiotics are solved.
Description
Technical field
The present invention relates to a kind of acne treatment purposes of Ampelopsis grossedentata extrat, belong to medicine, health food and cosmetics of everyday use field.
Background technology
Ampelopsis grossedentata, being commonly called as Maoyanmei tea, the Hakkas's Ramulus et Folium Mussaendae Pubescentis, Doanngo tea etc., is the young stem and leaf of Vitaceae Ampelopsis Ampelopsis grossedentata section, and primary growth is in China Chiang-Nan area.As a kind of tea-leaf beverage, Ampelopsis grossedentata is subject to general welcome at south China, and because of effect of its clearing away heat-damp and promoting diuresis, suppressing the hyperactive liver blood pressure lowering, promoting blood circulation to remove obstruction in the collateral, the Tus are referred to as " refreshing tea ".Modern study finds that Ampelopsis grossedentata has the effects such as heat-clearing and toxic substances removing, blood fat-reducing blood pressure-decreasing and anti-inflammation, and does not find any toxic and side effects, is a kind of excellent health promoting beverage, is regarded as new resource food by Ministry of Public Health.Ampelopsis grossedentata is rich in natural selenium and flavonoid, and contain the necessary nutrition of multiple human body, Ampelopsis grossedentata calcium, ferrum, content of magnesium are high, there is good preventive effect to cardiovascular disease such as arrhythmia, myocardial ischemia, hypertension, coronary heart disease, atherosclerosiss, also have good health-care effect to osteoporosis.The dietary fiber be rich in Ampelopsis grossedentata, carotene and vitamin E, have certain preventive effect to cancer, and meanwhile, Ampelopsis grossedentata all has inhibitory action to gram negative bacteria, influenza A type and B virus.
Ampelopsis grossedentata is auxiliary antilipemic as the function that health product are main, and main product prays board Ampelopsis grossedentata by the Feng Ming board Ampelopsis grossedentata of Enshi Feng Ming Ampelopsis grossedentata Co., Ltd exploitation and gold.Ampelopsis grossedentata applicating history is long, the patent of having applied for is numerous, at present the relevant patent of Ampelopsis grossedentata mainly concentrates on (1) extraction and preparation technique, as the method for DHM and polysaccharide " under a kind of low temperature in comprehensive extraction Ampelopsis grossedentata ", the extracting method of flavone " in a kind of Ampelopsis grossedentata "; (2) medicinal usage, as " a kind of adjustment hyperlipidemia Chinese medicine preparation ", " one protects the liver alimentation composition and protects the liver nutraceutical ", " a kind of compositions with sobering up and liver protecting functions ", " Ampelopsis grossedentata preparation of a kind of blood sugar lowering, blood fat, blood pressure and preparation method thereof ", " a kind of medicinal or health composition containing natural antibacterial agent "; (3) health care of food product purposes, as " composite beverage of a kind of Ramulus et Folium Mussaendae Pubescentis and Ampelopsis grossedentata and method for making thereof ", " a kind of compound health-care tea containing Ampelopsis grossedentata and preparation method thereof ", " a kind of method prepared by throat-protecting functional herbal beverage "; (3) agricultural use, as " a kind of selenium-enriched foliage fertilizer of Ampelopsis grossedentata ", " Ampelopsis grossedentata extrat is improving the application in Oryza sativa L. deterioration percentage of seedgermination ", " a kind of composite natural plant extract Oryza glutinosa antifungus agent and preparation method thereof "; (4) cosmetics of everyday use, as " Chinese medicinal herb functional shampoo be made up of Ampelopsis grossedentata and Radix Arnebiae (Radix Lithospermi) ".We in use find that the water extract of Ampelopsis grossedentata has significant therapeutic effect to acne.
Acne is commonly called as acne, skin sore or comedo, and be one of the most common dermatosis, clinical manifestation is chronic scytitis, not only affects the skin health of patient, and easily affect patient's particularly teen-age psychology and social activity etc.The pathogenic factor of acne is a lot, and wherein one of acnegenic of paramount importance reason is led in the large good breeding of propionibacterium acnes.Mostly the medicine of current treatment is antibiotic, and therapeutic effect is bad, and has toxic and side effects, can not life-time service, can cause certain damage to skin of face simultaneously.The extract that the present invention relates to a kind of Ampelopsis grossedentata can effectively suppress propionibacterium acnes to be bred, and effectively reduces the inflammatory reaction that propionibacterium acnes causes, finally cures acne.Meanwhile, the extract that the present invention relates to from natural Ampelopsis grossedentata, has no adverse reaction completely, can life-time service.
Summary of the invention
1 goal of the invention: the Ampelopsis grossedentata extrat that the invention provides a kind of pure natural is used for the treatment of acne.
2 technology contents:
The extracting method of Ampelopsis grossedentata extrat involved in the present invention is: hot-water soak Ampelopsis grossedentata, and fine straining goes out solid impurity, vacuum-concentrcted, spray dried into powder form.
Extract involved in the present invention shows to have definite curative effect to acne after human body examination clothes, using method is: get Ampelopsis grossedentata extrat 0.8g and be dissolved in hot water and make in paste, to be applied in affected part, sooner or later each once, separately get Ampelopsis grossedentata extrat 0.8g hot water to take after mixing it with water, sooner or later respectively once.Take effect: (1) grandson be willing to, man, 30 years old, disease sites: face is irregular distribution.Symptom: pachylosis, has pox to print, and acne are red, swollen, pain with white pus.Result of use: analgesis after 3 days, red and swollen range shorter, after two weeks, small pox significantly reduces, and when continuing to use to 28 days, small pox is red, swollen, the transference cure of pain, and part pox print disappears, and acne is cured substantially; (2) Sun Le, man, 26 years old, disease sites: cheek.Symptom: the small and dense collection of small pox, has pox to print, sensation that is red, swollen, pain is lighter.Result of use: after using one week, the anesthesia of red, swollen, pain, small pox starts to come off, and uses after surrounding, and pox print lighter, skin quality significantly improves.
The present invention adopts the method for external spawn culture, evaluate the impact that Ampelopsis grossedentata extrat is bred propionibacterium acnes, result shows that Ampelopsis grossedentata extrat significantly can suppress the propagation of propionibacterium acnes, and minimum inhibitory concentration is less than 5mg/ml, can effective Acne treatment.
Detailed description of the invention
1 vitro inhibition propionibacterium acnes activity experiment
Key instrument and reagent
Propionibacterium acnes lyophilizing bacterial strain (ATCC6919) is provided by Fu Xiang bio tech ltd, Shanghai; Improvement GAM broth bouillon (Qingdao Hai Bo Bioisystech Co., Ltd); Anaerobic jar, anaerobic gas generation bag and Anaerobic indicator (Mitsubishi gas KCC); Biohazard Safety Equipment (Su Xin purifying apparatus company limited); Isothermal vibration incubator (the magnificent Instrument Ltd. in granary).
Major experimental step
Sulfur ethylate culture medium recovery strain, by the strain plate streaking after recovery after 48 hours, cultivates 72 hours in anaerobism box; Picking monoclonal is placed in sulfur ethylate culture medium and cultivates 24 hours; Improvement GAM Letheen Broth culture medium pour plate, 15ml/ ware; Ampelopsis grossedentata extrat concentration is respectively 80mg/ml, 40mg/ml, 20mg/ml, 10mg/ml, 5mg/ml, 1.25mg/ml, gets 500ul extract solution and coats in improvement GAM agar plate, arrange feminine gender, the positive and blank simultaneously; Bacterium liquid in sulfur ethylate is diluted 100 times, coats in corresponding agar plate, Anaerobic culturel 72 hours; Take out agar plate, colony counting, the results are shown in Table 1.
The colony counting of table 1 Ampelopsis grossedentata extrat bacteriostatic experiment
| Ampelopsis grossedentata extrat concentration (mg/ml) | Clump count (individual) |
| 80 | 2 |
| 40 | 64 |
| 20 | 138 |
| 10 | 172 |
| 5 | 182 |
| 1.25 | 326 |
| Contrast | Clump count (individual) |
| Positive control | 0 |
| Negative control | 284 |
| Blank | 0 |
Claims (4)
1. the present invention relates to a kind of suppression acne purposes of Ampelopsis grossedentata extrat, it is characterized in that: the water extract that (a) is Ampelopsis grossedentata, Ampelopsis grossedentata is placed in hot water (90 ~ 100 DEG C) and soaks, and fine straining goes out solid impurity, vacuum-concentrcted, spray dried into powder form; B () significantly can suppress the breeding of propionibacterium acnes.
2. according to the Ampelopsis grossedentata extrat described in claim 1 and/or its compositions as Drug therapy acne.
3. according to the Ampelopsis grossedentata extrat described in claim 1 and/or its compositions as health product auxiliary treatment acne.
4. according to the Ampelopsis grossedentata extrat described in claim 1 and/or its compositions as cosmetics of everyday use, Acne treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410130834.4A CN104971161A (en) | 2014-04-02 | 2014-04-02 | Application of vine tea extract in treatment of acnes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410130834.4A CN104971161A (en) | 2014-04-02 | 2014-04-02 | Application of vine tea extract in treatment of acnes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104971161A true CN104971161A (en) | 2015-10-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410130834.4A Pending CN104971161A (en) | 2014-04-02 | 2014-04-02 | Application of vine tea extract in treatment of acnes |
Country Status (1)
| Country | Link |
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| CN (1) | CN104971161A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107519083A (en) * | 2017-08-28 | 2017-12-29 | 李冉冉 | Toner containing natural plant extracts |
| CN109999175A (en) * | 2019-04-10 | 2019-07-12 | 孙和平 | It is a kind of for eliminating the compound formulation and preparation method thereof of dark sore abscess dermatitis infections acne ulcer |
| CN112494571A (en) * | 2020-12-12 | 2021-03-16 | 段爱菊 | A tea composition for treating dermatoses and trauma, and its preparation method |
| CN116808115A (en) * | 2023-05-31 | 2023-09-29 | 姚美华 | Application of ampelopsis grossedentata extract in preparation of antibacterial and/or repairing products |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1398633A (en) * | 2002-08-22 | 2003-02-26 | 郑崇标 | Throat-moistening wild tea |
-
2014
- 2014-04-02 CN CN201410130834.4A patent/CN104971161A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1398633A (en) * | 2002-08-22 | 2003-02-26 | 郑崇标 | Throat-moistening wild tea |
Non-Patent Citations (1)
| Title |
|---|
| 张育松: "《福建名茶》", 31 January 2013, 厦门大学出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107519083A (en) * | 2017-08-28 | 2017-12-29 | 李冉冉 | Toner containing natural plant extracts |
| CN109999175A (en) * | 2019-04-10 | 2019-07-12 | 孙和平 | It is a kind of for eliminating the compound formulation and preparation method thereof of dark sore abscess dermatitis infections acne ulcer |
| CN112494571A (en) * | 2020-12-12 | 2021-03-16 | 段爱菊 | A tea composition for treating dermatoses and trauma, and its preparation method |
| CN116808115A (en) * | 2023-05-31 | 2023-09-29 | 姚美华 | Application of ampelopsis grossedentata extract in preparation of antibacterial and/or repairing products |
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| DD01 | Delivery of document by public notice |
Addressee: Xie Tianpei Document name: Notification of Passing Preliminary Examination of the Application for Invention |
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| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20151014 |
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| WD01 | Invention patent application deemed withdrawn after publication |