CN114504525A - Acne-removing cream containing hamamelis virginiana component and preparation method thereof - Google Patents
Acne-removing cream containing hamamelis virginiana component and preparation method thereof Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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Abstract
The invention relates to an acne-removing cream containing hamamelis virginiana components, which comprises 4-8 parts of propylene glycol, 2-5 parts of ethylhexyl palmitate, 1-4 parts of cetearyl alcohol, 1-3 parts of cetearyl glucoside, 0.5-1 part of glycerol stearate, 0.25-0.75 part of PEG-100 stearate, 0.6-1 part of PEG-20 methyl glucose sesquistearate, 0.4-0.8 part of butanediol, 0.1-0.3 part of glycyrrhiza inflate extract, 0.2-0.5 part of scutellaria baicalensis root extract, 2-4 parts of hamamelis virginiana extract and 0.5-0.8 part of ethylhexylglycerin, 0.4-0.7 parts of sophora flavescens root extract, 0.2-0.5 parts of bisabolol, 0.4-0.6 parts of ergothioneine, 0.3-0.8 parts of 1, 2-hexanediol, 0.2-0.4 parts of tocopherol acetate, 0.1-0.2 parts of salicylic acid, 0.2-0.5 parts of xanthan gum, 0.05-0.1 parts of pH regulator, 0.1-0.4 parts of cajeput oil, 0.1-0.2 parts of hexamidine dihydrochloride, 0.75-1.38 parts of preservative and the balance of water. The invention also discloses a corresponding preparation method of the acne-removing cream. The invention has synergistic effect, and has the effects of resisting inflammation, removing acne, tranquilizing, resisting allergy, moisturizing, locking water and the like.
Description
Technical Field
The invention belongs to the field of cosmetics, and particularly relates to acne-removing face cream and a preparation method thereof.
Background
In adolescent human body, the male hormone is easy to be over-secreted, the sebaceous gland is hypertrophic, the sebum is over-secreted, the pore is easy to be excreted unsmoothly, and the sebum is accumulated in the hair follicle to form the lipid plug. Prolonged secondary bacterial infection causes inflammatory reactions around the pilosebaceous glands, forming papules or pustules. At present, tea tree essential oil is generally used as a main functional raw material in the traditional acne removing products, but the tea tree essential oil has the characteristics of oiliness, dryness, neutrality and mixability in skin classification, and the tea tree essential oil has a poor acne removing effect on oiliness skin.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide the face cream which takes the ingredients of Hamamelis virginiana as main functional raw materials and has certain acne removing effect on various skins.
The second purpose of the invention is to provide a preparation method of the acne-removing cream.
In order to solve the technical problems, the invention adopts the following technical scheme: an acne-removing cream containing hamamelis virginiana components is prepared from the following components in percentage by weight:
4 to 8 parts of propylene glycol, 2 to 5 parts of ethylhexyl palmitate, 1 to 4 parts of cetearyl alcohol, 1 to 3 parts of cetearyl glucoside, 0.5 to 1 part of glyceryl stearate, 0.25 to 0.75 part of PEG-100 stearate, 0.6 to 1 part of PEG-20 methyl glucose sesquistearate, 0.4 to 0.8 part of butylene glycol, 0.1 to 0.3 part of licorice root (IGCYRRHIZA INFLATA) root extract, 0.2 to 0.5 part of Scutellaria BAICALENSIS (SCUTELLARIA BAICALENSIS) root extract, 2 to 4 parts of Hamamelis Virginiana (HAMAMELIS VIRGINIANA) extract, 0.5 to 0.8 part of ethylhexylglycerin, 0.4 to 0.7 part of Sophora flavescens root (SOROAANGUSTIFOLIA) root extract, 0.2 to 0.5 part of bisabolol, 0.4 to 0.6 part of ergothionein, 0.3 to 0.8 part of 1, 0.2.4 to 0.0.5 part of salicylic acid acetate, 0.1.0.0.0.0.1 to 0.5 part of salicylic acid, 0.0.1 to 0.05 part of citric acid, 0.0.1 to 0.1.8 parts of FOLIPEAK oil, 0.05 to 0.0.0.0.0.1 part of FOLIPA, 0.8 parts of FOLIP-0.0.0.0.0.0.0.0.1 part of FOLIP-1-2-1-2-1-ethyl-1-2-1-2-ethyl-1-2-1-2-1-2-1-2-ethyl-2-1-2-1-ethyl-1-2-ethyl-1-2-D-2-D, The balance being water. Wherein the water is deionized water or distilled water.
According to the scheme, propylene glycol, butanediol, ethylhexyl palmitate, cetearyl alcohol, cetearyl glucoside, glyceryl stearate, PEG-100 stearate and PEG-20 methyl glucose sesquistearate are used as oil phase substrates, so that the moisturizing cream has good moisturizing effect, and is economical and cheap in raw materials and free of toxic and side effects; the acne-removing and freckle-removing composition is matched with the Hamamelis virginiana, the glycyrrhiza inflate root extract and the scutellaria baicalensis root extract, can improve the local estrogen level of the cortex, can enhance the metabolism of skin cells, has the effects of resisting oxidation, ageing and inflammation, preventing allergy, relaxing and astringing, can maintain the elasticity and wrinkle of the skin, and has good water holding capacity; and finally, the skin conditioning agents such as ethyl hexyl glycerol, the extract of the roots of the sophora flavescens, bisabolol, ergothioneine, 1, 2-hexanediol, tocopheryl acetate, salicylic acid, xanthan gum, disodium EDTA, cajeput oil, hexamidine dihydrochloride and the like are matched to enhance the effects of moisturizing, anti-allergy, antioxidation, restoration, whitening, acne resistance, acne removal and the like of the product.
Preferably, the preservative is one or more of p-hydroxyacetophenone, phenoxyethanol, chlorpyrifos, methylparaben and propylparaben. Further, the preservative comprises 0.2-0.3 of p-hydroxyacetophenone, 0.2-0.3 of phenoxyethanol, 0.05-0.08 of chlorpyrifos, 0.2-0.4 of methyl hydroxybenzoate and 0.1-0.3 of propyl hydroxybenzoate.
Preferably, the pH regulator adopts EDTA disodium.
Preferably, the color agent also comprises 0.001-0.002 of color agent, wherein the color agent adopts CI19140 (lemon yellow).
Preferably, the acne cream comprises the following components: propylene glycol 5, ethylhexyl palmitate 3, cetearyl alcohol 2, cetearyl glucoside 2, glyceryl stearate 0.5, PEG-100 stearate 0.5, PEG-20 methylglucamine sesquistearate 0.6, butylene glycol 0.5, glycyrrhiza inflate extract 0.1, scutellaria baicalensis root extract 0.2, Hamamelis virginiana extract 2, ethylhexylglycerol 0.5, radix Sophorae Flavescentis extract 0.5, bisabolol 0.3, ergothioneine 0.5, 1, 2-hexanediol 0.5, p-hydroxyacetophenone 0.4, tocopheryl acetate 0.2, phenoxyethanol 0.2, chlorphenesin 0.05, methylparaben 0.2, propylhydroxybenzoate 0.1, salicylic acid 0.1, xanthan gum 0.2, EDTA disodium 0.05, hexidine dihydrochloride 0.1, melaleuca pentandra 0.1, CI191400.001, and the balance water.
The invention also discloses a preparation method of the acne-removing cream, which comprises the following steps:
s1, accurately weighing various raw materials in a formula, and placing the raw materials in a clean and sterilized utensil;
s2, uniformly dispersing the disodium EDTA with the propylene glycol, adding the hexamidine dihydrochloride, stirring and dissolving, and heating to 80-83 ℃;
s3, adding the ethylhexyl palmitate, the cetearyl alcohol, the cetearyl glucoside, the glyceryl stearate, the PEG-100 stearate, the PEG-20 methyl glucose sesquistearate, the ethyl hexyl glycerol, the bisabolol, the p-hydroxyacetophenone, the tocopheryl acetate, the phenoxyethanol, the chlorpyrifos, the methylparaben, the propylhydroxybenzoate, the xanthan gum and the cajeput oil into an oil phase pot, mixing and heating to 80-83 ℃, uniformly stirring and completely dissolving the materials, and keeping the temperature for 5-7 minutes;
s4, pumping the material prepared in the step S3 into an emulsifying pot, vacuumizing, stirring and homogenizing at the rotating speed of 2700RPM for 6-10 minutes, and then stirring and cooling to 48 ℃; adding the glycyrrhiza inflate extract, the scutellaria baicalensis root extract, the hamamelis virginiana extract, the sophora flavescens root extract, the ergothioneine, the 1, 2-hexanediol and the aqueous solution prepared in the step S2, continuously vacuumizing, stirring and homogenizing at 2700RPM for 4-6 minutes, and preserving heat for 6-10 minutes;
s5, adding the salicylic acid and CI19140 into the system, carrying out vacuum homogenization for 3 minutes at the rotating speed of 2700RPM, then continuing stirring and cooling to 35-38 ℃, discharging, and standing to normal temperature.
Compared with the prior art, the invention has the following beneficial effects: the components of the acne cream are mild in formula, free of stimulation, synergistic, good in skin permeability, capable of quickly and effectively moistening skin, and capable of resisting inflammation, removing acne, calming, resisting allergy, preserving moisture and locking water and the like.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
In order to better illustrate the present disclosure, several preferred embodiments are described below. However, these specific examples are only for illustrating the present invention and are not intended to limit the present invention.
An acne-removing cream containing hamamelis virginiana components is prepared from the following components in percentage by weight: 4 to 8 parts of propylene glycol, 2 to 5 parts of ethylhexyl palmitate, 1 to 4 parts of cetearyl alcohol, 1 to 3 parts of cetearyl glucoside, 0.5 to 1 part of glyceryl stearate, 0.25 to 0.75 part of PEG-100 stearate, 0.6 to 1 part of PEG-20 methyl glucose sesquistearate, 0.4 to 0.8 part of butylene glycol, 0.1 to 0.3 part of licorice root (IGCYRRHIZA INFLATA) root extract, 0.2 to 0.5 part of Scutellaria BAICALENSIS (SCUTELLARIA BAICALENSIS) root extract, 2 to 4 parts of Hamamelis Virginiana (HAMAMELIS VIRGINIANA) extract, 0.5 to 0.8 part of ethylhexylglycerin, 0.4 to 0.7 part of Sophora flavescens root (SOROAANGUSTIFOLIA) root extract, 0.2 to 0.5 part of bisabolol, 0.4 to 0.6 part of ergothionein, 0.3 to 0.8 part of 1, 0.2.4 to 0.0.5 part of salicylic acid acetate, 0.1.0.0.0.0.1 to 0.5 part of salicylic acid, 0.0.1 to 0.05 part of citric acid, 0.0.1 to 0.1.8 parts of FOLIPEAK oil, 0.05 to 0.0.0.0.0.1 part of FOLIPA, 0.8 parts of FOLIP-0.0.0.0.0.0.0.0.1 part of FOLIP-1-2-1-2-1-ethyl-1-2-1-2-ethyl-1-2-1-2-1-2-1-2-ethyl-2-1-2-1-ethyl-1-2-ethyl-1-2-D-2-D, The balance being water. Wherein the water is deionized water or distilled water.
Preferably, the preservative is one or more of p-hydroxyacetophenone, phenoxyethanol, chlorpyrifos, methylparaben and propylparaben. Further, the preservative comprises 0.2-0.3 of p-hydroxyacetophenone, 0.2-0.3 of phenoxyethanol, 0.05-0.08 of chlorpyrifos, 0.2-0.4 of methyl hydroxybenzoate and 0.1-0.3 of propyl hydroxybenzoate.
Preferably, the pH regulator adopts EDTA disodium.
Preferably, the color agent also comprises 0.001-0.002 of color agent, wherein the color agent adopts CI19140 (lemon yellow).
According to the scheme, propylene glycol, butanediol, ethylhexyl palmitate, cetearyl alcohol, cetearyl glucoside, glyceryl stearate, PEG-100 stearate and PEG-20 methyl glucose sesquistearate are used as oil phase substrates, so that the moisturizing cream has good moisturizing effect, and is economical and cheap in raw materials and free of toxic and side effects; the acne-removing and freckle-removing composition is matched with the Hamamelis virginiana, the glycyrrhiza inflate root extract and the scutellaria baicalensis root extract, can improve the local estrogen level of the cortex, can enhance the metabolism of skin cells, has the effects of resisting oxidation, ageing and inflammation, preventing allergy, relaxing and astringing, can maintain the elasticity and wrinkle of the skin, and has good water holding capacity; and finally, the skin conditioning agents such as ethyl hexyl glycerol, the extract of the roots of the sophora flavescens, bisabolol, ergothioneine, 1, 2-hexanediol, tocopheryl acetate, salicylic acid, xanthan gum, disodium EDTA, cajeput oil, hexamidine dihydrochloride and the like are matched to enhance the effects of moisturizing, anti-allergy, antioxidation, restoration, whitening, acne resistance, acne removal and the like of the product.
The invention also discloses a preparation method of the acne-removing cream, which comprises the following steps:
s1, accurately weighing various raw materials in a formula, and placing the raw materials in a clean and sterilized utensil;
s2, uniformly dispersing the disodium EDTA with the propylene glycol, adding the hexamidine dihydrochloride, stirring and dissolving, and heating to 80-83 ℃;
s3, adding the ethylhexyl palmitate, the cetearyl alcohol, the cetearyl glucoside, the glyceryl stearate, the PEG-100 stearate, the PEG-20 methyl glucose sesquistearate, the ethyl hexyl glycerol, the bisabolol, the p-hydroxyacetophenone, the tocopheryl acetate, the phenoxyethanol, the chlorpyrifos, the methylparaben, the propylhydroxybenzoate, the xanthan gum and the cajeput oil into an oil phase pot, mixing and heating to 80-83 ℃, uniformly stirring and completely dissolving the materials, and keeping the temperature for 5-7 minutes;
s4, pumping the material prepared in the step S3 into an emulsifying pot, vacuumizing, stirring and homogenizing at the rotating speed of 2700RPM for 6-10 minutes, and then stirring and cooling to 48 ℃; adding the glycyrrhiza inflate extract, the scutellaria baicalensis root extract, the hamamelis virginiana extract, the sophora flavescens root extract, the ergothioneine, the 1, 2-hexanediol and the aqueous solution prepared in the step S2, continuously vacuumizing, stirring and homogenizing at 2700RPM for 4-6 minutes, and preserving heat for 6-10 minutes;
s5, adding the salicylic acid and the CI19140 into the system, carrying out vacuum homogenization for 3 minutes at the rotating speed of 2700RPM, then continuing stirring and cooling to 35-38 ℃, discharging, and standing to normal temperature.
Example 1
The preparation method comprises the following steps:
s1, accurately weighing various raw materials in a formula, and placing the raw materials in a clean and sterilized utensil;
s2, uniformly dispersing the disodium EDTA with the propylene glycol, adding the hexamidine dihydrochloride, stirring and dissolving, and heating to 80-83 ℃;
s3, adding the ethylhexyl palmitate, the cetearyl alcohol, the cetearyl glucoside, the glyceryl stearate, the PEG-100 stearate, the PEG-20 methyl glucose sesquistearate, the ethyl hexyl glycerol, the bisabolol, the p-hydroxyacetophenone, the tocopheryl acetate, the phenoxyethanol, the chlorpyrifos, the methylparaben, the propylhydroxybenzoate, the xanthan gum and the cajeput oil into an oil phase pot, mixing and heating to 80-83 ℃, uniformly stirring and completely dissolving the materials, and keeping the temperature for 5-7 minutes;
s4, pumping the material prepared in the step S3 into an emulsifying pot, vacuumizing, stirring and homogenizing at the rotating speed of 2700RPM for 6-10 minutes, and then stirring and cooling to 48 ℃; adding the glycyrrhiza inflate extract, the scutellaria baicalensis root extract, the hamamelis virginiana extract, the sophora flavescens root extract, the ergothioneine, the 1, 2-hexanediol and the aqueous solution prepared in the step S2, continuously vacuumizing, stirring and homogenizing at 2700RPM for 4-6 minutes, and preserving heat for 6-10 minutes;
s5, adding the salicylic acid and the CI19140 into the system, carrying out vacuum homogenization for 3 minutes at the rotating speed of 2700RPM, then continuing stirring and cooling to 35-38 ℃, discharging, and standing to normal temperature.
Example 2
The preparation method is similar to example 1.
Safety and efficacy evaluation test
The safety and efficacy of the acne cream of the invention are evaluated as follows:
the safety test method of the acne-removing cream comprises the following steps: 30 test subjects were selected to perform the spot test on the acne cream products of example 1 and example 2, and the skin reaction was observed after 24 hours by visual observation:
through the patch test, the test subjects of the above example 1 and example 2 have no adverse reaction.
The efficacy test of the acne-removing cream is to detect and evaluate the effect of the acne-removing cream on propionibacterium acnes through an inhibition test, namely, the propionibacterium acnes is put into a culture medium containing the acne-removing cream products of the above example 1 and example 2, then the growth and the reproduction of the propionibacterium acnes are observed,
the test results show that the acne-removing and freckle-removing composition prepared from the witch hazel, the glycyrrhiza inflata root extract and the scutellaria baicalensis root extract has good anti-inflammatory and acne-removing effects.
It is to be noted that the sources of the raw materials and reagents used in the present invention are commercially available, and the experimental method of the present invention, in which the specific conditions are not specified, is generally carried out according to the conventional conditions or the conditions recommended by the manufacturers.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents and are included in the scope of the present invention.
Claims (9)
1. An acne-removing cream containing hamamelis virginiana components is characterized by being prepared from the following components in percentage by weight:
4-8 parts of propylene glycol, 2-5 parts of ethylhexyl palmitate, 1-4 parts of cetearyl alcohol, 1-3 parts of cetearyl glucoside, 0.5-1 part of glyceryl stearate, 0.25-0.75 part of PEG-100 stearate, 0.6-1 part of PEG-20 methyl glucose sesquistearate, 0.4-0.8 part of butanediol, 0.1-0.3 part of liquorice root extract, 0.2-0.5 part of scutellaria root extract, 2-4 parts of witch hazel extract, 0.5-0.8 part of ethyl hexyl glycerol, 0.4-0.7 part of sophora flavescens root extract, 0.2-0.5 part of bisabolol, 0.4-0.6 part of ergothioneine, 0.3-0.8 part of 1, 2-hexanediol, 0.2-0.4 part of tocopherol acetate, 0.1-0.2 part of salicylic acid, 0.2-0.5 part of xanthan gum, 0.05-0.1 part of pH regulator, 0.1 part of cajeput oil, 0.1-0.38 parts of chlorhexidine dihydrochloride and the balance of preservative.
2. The acne-removing cream containing hamamelis virginiana components according to claim 1, wherein the acne-removing cream comprises the following components in percentage by weight: the antiseptic is one or more of p-hydroxyacetophenone, phenoxyethanol, chlorpyrifos, methyl hydroxybenzoate and propyl hydroxybenzoate.
3. The acne cream containing hamamelis virginiana components according to claim 1 or 2, wherein the acne cream comprises the following components in percentage by weight: the preservative comprises 0.2-0.3 of p-hydroxyacetophenone, 0.2-0.3 of phenoxyethanol, 0.05-0.08 of chlorobenzene myzus cumini, 0.2-0.4 of methyl hydroxybenzoate and 0.1-0.3 of propyl hydroxybenzoate.
4. The acne-removing cream containing hamamelis virginiana components according to claim 1, wherein the acne-removing cream comprises the following components in percentage by weight: the pH regulator adopts EDTA disodium.
5. The acne-removing cream containing hamamelis virginiana components according to claim 1, wherein the acne-removing cream comprises the following components in percentage by weight: also comprises 0.001-0.002 of colorant.
6. The acne-removing cream containing hamamelis virginiana components according to claim 5, wherein the acne-removing cream comprises the following components in percentage by weight: the colorant was CI 19140.
7. The acne cream containing hamamelis virginiana ingredients in claim 1, which is prepared from the following components in percentage by weight: propylene glycol 5, ethylhexyl palmitate 3, cetearyl alcohol 2, cetearyl glucoside 2, glyceryl stearate 0.5, PEG-100 stearate 0.5, PEG-20 methylglucamine sesquistearate 0.6, butylene glycol 0.5, glycyrrhiza inflate extract 0.1, scutellaria baicalensis root extract 0.2, Hamamelis virginiana extract 2, ethylhexylglycerol 0.5, radix Sophorae Flavescentis extract 0.5, bisabolol 0.3, ergothioneine 0.5, 1, 2-hexanediol 0.5, p-hydroxyacetophenone 0.4, tocopheryl acetate 0.2, phenoxyethanol 0.2, chlorphenesin 0.05, methylparaben 0.2, propylhydroxybenzoate 0.1, salicylic acid 0.1, xanthan gum 0.2, EDTA disodium 0.05, hexidine dihydrochloride 0.1, melaleuca pentandra 0.1, CI191400.001, and the balance water.
8. The anti-acne cream containing hamamelis virginiana components according to claim 1 or 7, wherein the water is deionized water or distilled water.
9. The preparation method of the acne cream containing the hamamelis virginiana component according to any one of claims 1 to 7, wherein the steps are as follows:
s1, accurately weighing various raw materials in a formula, and placing the raw materials in a clean and sterilized utensil;
s2, uniformly dispersing the disodium EDTA with the propylene glycol, adding the hexamidine dihydrochloride, stirring for dissolving, and heating to 80-83 ℃;
s3, adding the ethylhexyl palmitate, the cetearyl alcohol, the cetearyl glucoside, the glyceryl stearate, the PEG-100 stearate, the PEG-20 methyl glucose sesquistearate, the ethylhexyl glycerol, the bisabolol, the p-hydroxyacetophenone, the tocopherol acetate, the phenoxyethanol, the chlorpyrifos, the methylparaben, the propylparaben, the xanthan gum and the cajeput oil into an oil phase pot, mixing and heating to 80-83 ℃, uniformly stirring and completely dissolving the mixture, and keeping the temperature for 5-7 minutes;
s4, pumping the material prepared in the step S3 into an emulsifying pot, vacuumizing, stirring and homogenizing at 2700RPM for 6-10 minutes, and then stirring and cooling to 48 ℃; adding the glycyrrhiza inflate root extract, the scutellaria baicalensis root extract, the witch hazel extract, the sophora flavescens root extract, the ergothioneine, the 1, 2-hexanediol and the aqueous solution prepared in the step S2, continuously vacuumizing, stirring and homogenizing at 2700RPM for 4-6 minutes, and preserving heat for 6-10 minutes;
s5, adding the salicylic acid and the CI19140 into the system, carrying out vacuum homogenization for 3 minutes at the rotating speed of 2700RPM, then continuing stirring and cooling to 35-38 ℃, discharging, and standing to normal temperature.
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CN116509782A (en) * | 2023-05-11 | 2023-08-01 | 百肽德医药生物科技(广东)有限公司 | Acne-removing factor and cosmetics thereof |
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