CN101362733B - 头孢克肟侧链酸活性酯的制备方法 - Google Patents
头孢克肟侧链酸活性酯的制备方法 Download PDFInfo
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- CN101362733B CN101362733B CN200810140236XA CN200810140236A CN101362733B CN 101362733 B CN101362733 B CN 101362733B CN 200810140236X A CN200810140236X A CN 200810140236XA CN 200810140236 A CN200810140236 A CN 200810140236A CN 101362733 B CN101362733 B CN 101362733B
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CN200810140236XA CN101362733B (zh) | 2008-09-16 | 2008-09-16 | 头孢克肟侧链酸活性酯的制备方法 |
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CN200810140236XA CN101362733B (zh) | 2008-09-16 | 2008-09-16 | 头孢克肟侧链酸活性酯的制备方法 |
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CN101362733A CN101362733A (zh) | 2009-02-11 |
CN101362733B true CN101362733B (zh) | 2012-07-25 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104496937A (zh) * | 2014-11-21 | 2015-04-08 | 山东金城医药化工股份有限公司 | 头孢他啶侧链酸活性酯的合成方法 |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101747291B (zh) * | 2009-12-22 | 2011-06-22 | 山东鑫泉医药中间体有限公司 | 一种ae-活性酯的合成方法 |
CN106380467A (zh) * | 2016-08-29 | 2017-02-08 | 山东金城柯瑞化学有限公司 | 头孢克肟侧链酸活性酯的制备方法 |
CN107513047B (zh) * | 2017-09-22 | 2020-08-18 | 山东金城医药化工有限公司 | 微波辅助法合成头孢他啶侧链酸活性酯的绿色工艺 |
CN109280036A (zh) * | 2018-09-06 | 2019-01-29 | 珠海市格特生物科技有限公司 | 头孢克肟侧链活性酯工艺合成方法 |
CN110041346B (zh) * | 2019-04-17 | 2022-06-07 | 广东立国制药有限公司 | 一种低成本的头孢克肟的制备方法 |
CN112110872B (zh) * | 2020-09-16 | 2022-12-16 | 上海应用技术大学 | 一种头孢类活性酯中间体及其连续制备方法 |
CN112830903A (zh) * | 2020-12-29 | 2021-05-25 | 山东金城柯瑞化学有限公司 | 头孢克肟侧链酸活性酯的制备方法 |
CN113956214B (zh) * | 2021-11-10 | 2023-12-26 | 山东普洛得邦医药有限公司 | 一种连续合成头孢克肟侧链酸活性酯的方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2006103686A1 (en) * | 2005-03-29 | 2006-10-05 | Hetero Drugs Limited | An improved process for the preparation of cefixime |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2006103686A1 (en) * | 2005-03-29 | 2006-10-05 | Hetero Drugs Limited | An improved process for the preparation of cefixime |
Non-Patent Citations (4)
Title |
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刘桂成.头孢克肟活性酯(mica酯)的合成.《精细与专用化学品》.2009,第17卷(第8期),24-26. |
王荣耕 |
王荣耕;刘桂成.头孢克肟活性酯(mica酯)的合成.《精细与专用化学品》.2009,第17卷(第8期),24-26. * |
葛洪玉,马卫兴,许兴友.头孢克肟侧链活性酯的合成.《中国新药杂志》.2008,第17卷(第2期),135-137. * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104496937A (zh) * | 2014-11-21 | 2015-04-08 | 山东金城医药化工股份有限公司 | 头孢他啶侧链酸活性酯的合成方法 |
CN104496937B (zh) * | 2014-11-21 | 2016-09-28 | 山东金城医药股份有限公司 | 头孢他啶侧链酸活性酯的合成方法 |
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CN101362733A (zh) | 2009-02-11 |
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Application publication date: 20090211 Assignee: SHANDONG JINCHENG COURAGE CHEMICAL Co.,Ltd. Assignor: SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL Co.,Ltd. Contract record no.: 2013370000248 Denomination of invention: Method for preparing cefixime side chain active ester Granted publication date: 20120725 License type: Exclusive License Record date: 20131204 |
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Effective date of registration: 20151026 Address after: 255100 Shandong Jincheng pharmaceutical chemical Limited by Share Ltd, Zichuan Economic Development Zone, Zibo, Shandong Patentee after: SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL Co.,Ltd. Patentee after: ZHONGSHAN JINCHENG DOBFAR PHARMACEUTICAL CO.,LTD. Address before: 255100 Shandong Jincheng pharmaceutical chemical Limited by Share Ltd, Zichuan Economic Development Zone, Zibo, Shandong Patentee before: SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL Co.,Ltd. |
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Address after: 255100 Shandong Jincheng pharmaceutical chemical Limited by Share Ltd, Zichuan Economic Development Zone, Zibo, Shandong Patentee after: SHANDONG JINCHENG PHARMACEUTICAL CO.,LTD. Patentee after: GUANGDONG JINCHENG JINSU PHARMACY Co.,Ltd. Address before: 255100 Shandong Jincheng pharmaceutical chemical Limited by Share Ltd, Zichuan Economic Development Zone, Zibo, Shandong Patentee before: SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL Co.,Ltd. Patentee before: ZHONGSHAN JINCHENG DOBFAR PHARMACEUTICAL CO.,LTD. |
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