CN115304526B - 一种水溶性氟苯尼考前药及其制备方法 - Google Patents
一种水溶性氟苯尼考前药及其制备方法 Download PDFInfo
- Publication number
- CN115304526B CN115304526B CN202211237242.3A CN202211237242A CN115304526B CN 115304526 B CN115304526 B CN 115304526B CN 202211237242 A CN202211237242 A CN 202211237242A CN 115304526 B CN115304526 B CN 115304526B
- Authority
- CN
- China
- Prior art keywords
- water
- florfenicol
- prodrug
- compound
- reaction step
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202211237242.3A CN115304526B (zh) | 2022-10-11 | 2022-10-11 | 一种水溶性氟苯尼考前药及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202211237242.3A CN115304526B (zh) | 2022-10-11 | 2022-10-11 | 一种水溶性氟苯尼考前药及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN115304526A CN115304526A (zh) | 2022-11-08 |
CN115304526B true CN115304526B (zh) | 2023-08-01 |
Family
ID=83867978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202211237242.3A Active CN115304526B (zh) | 2022-10-11 | 2022-10-11 | 一种水溶性氟苯尼考前药及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN115304526B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116178309A (zh) * | 2023-02-20 | 2023-05-30 | 华中农业大学 | 一种水溶性良好的氟苯尼考衍生物及其制备方法和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008076259A1 (en) * | 2006-12-13 | 2008-06-26 | Schering-Plough Ltd. | Water-soluble prodrugs of florfenicol and its analogs |
US7550625B2 (en) * | 2007-10-19 | 2009-06-23 | Idexx Laboratories | Esters of florfenicol |
-
2022
- 2022-10-11 CN CN202211237242.3A patent/CN115304526B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN115304526A (zh) | 2022-11-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2534131B1 (en) | Methods of synthesizing and isolating n-(bromoacetyl)-3,3-dinitroazetidine and a composition including the same | |
CN115304526B (zh) | 一种水溶性氟苯尼考前药及其制备方法 | |
CN108473524B (zh) | 一种泰拉霉素的制备方法及其中间体 | |
CA1240320A (en) | Azahomoerythromycin d derivative and intermediates therefor | |
CN115286544A (zh) | 一种氟苯尼考衍生物、制备方法及其在抗细菌感染的应用 | |
EP0080229B1 (en) | Salicylic derivatives of n-acetylcysteine | |
JPS58159499A (ja) | 抗菌剤として有用な4″−エピエリスロマイシンaおよびその誘導体 | |
CN103554203A (zh) | 一种泰地罗新无定形晶及其制备方法 | |
JP2005529082A5 (zh) | ||
CN108314696B (zh) | 2-羟基-1,3,5-三-O-苯甲酰基-α-D-呋喃核糖结晶母液的利用方法 | |
CN110642764A (zh) | 一种水溶性氟苯尼考钠盐的制备方法 | |
CN113121625B (zh) | 一种泰地罗新的制备方法 | |
CN102532168A (zh) | 头孢哌酮酸的合成方法 | |
CN112679570A (zh) | 一种泰地罗新的合成与纯化方法 | |
CN113801104A (zh) | 一种依维莫大环内酯水解杂质的制备方法 | |
CN111072730B (zh) | 一种泰拉霉素中间体盐的制备方法及应用 | |
IE47714B1 (en) | 4"-ureido-oleandomycin derivatives,process for their preparation and their use in pharmaceutical compositions | |
JPH01175956A (ja) | 光学的に純粋な3−ヒドロキシ酸類の精製法 | |
CN111004255A (zh) | 一种头孢卡品内酯化合物或其盐酸盐的制备方法 | |
CN111233894B (zh) | 一种头孢妥仑匹酯δ3异构体的制备方法 | |
CN111087433B (zh) | 一种泰拉霉素中间体的制备方法 | |
CN112694488B (zh) | 一种l型头孢孟多酯钠的合成方法 | |
CN110655543A (zh) | 一种泰拉霉素新晶型及其制备方法 | |
CN113372363B (zh) | 一种去氨甲酰头孢呋辛的制备方法 | |
CN101648983A (zh) | 4”取代的13-环氮杂内酯类的衍生物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20230615 Address after: 261,000 North 500 meters east of Xiangshan Town Community, Dawenhe Tourism Development Zone, Anqiu City, Weifang City, Shandong Province Applicant after: Shihua Hechuang Biotechnology Development (Shandong) Co.,Ltd. Address before: 262100 in the courtyard of East Weifang Fubang Pharmaceutical Co., Ltd., lijiabucun, Dawenhe Tourism Development Zone, Anqiu City, Weifang City, Shandong Province Applicant before: Weifang zhongkelibang Bioengineering Research Institute |
|
TA01 | Transfer of patent application right | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CB03 | Change of inventor or designer information |
Inventor after: Sun Xudong Inventor after: Yang Shangjin Inventor after: Shen Yufeng Inventor after: Zhang Zhengrong Inventor after: Ju Minglu Inventor before: Sun Xudong Inventor before: Yang Shangjin Inventor before: Shen Yufeng Inventor before: Zhang Zhengrong Inventor before: Ju Minglu |
|
CB03 | Change of inventor or designer information |