CN101360421B - 烟酰核苷组合物及其使用方法 - Google Patents

烟酰核苷组合物及其使用方法 Download PDF

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CN101360421B
CN101360421B CN200680051368.4A CN200680051368A CN101360421B CN 101360421 B CN101360421 B CN 101360421B CN 200680051368 A CN200680051368 A CN 200680051368A CN 101360421 B CN101360421 B CN 101360421B
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compound
cell
alkylamino
formula
amino
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CN101360421A (zh
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安东尼·安德鲁·索弗尔
杨天乐
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Cornell Research Foundation Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
CN200680051368.4A 2005-11-18 2006-11-17 烟酰核苷组合物及其使用方法 Active CN101360421B (zh)

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Application Number Priority Date Filing Date Title
US73808105P 2005-11-18 2005-11-18
US60/738,081 2005-11-18
PCT/US2006/044580 WO2007061798A2 (en) 2005-11-18 2006-11-17 Nicotinoyl riboside compositions and methods of use
US11/601,714 US8106184B2 (en) 2005-11-18 2006-11-17 Nicotinoyl riboside compositions and methods of use
US11/601,714 2006-11-17

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CN101360421A CN101360421A (zh) 2009-02-04
CN101360421B true CN101360421B (zh) 2014-06-18

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EP (3) EP3369738B1 (US08106184-20120131-C00054.png)
CN (1) CN101360421B (US08106184-20120131-C00054.png)
DK (1) DK1957086T3 (US08106184-20120131-C00054.png)
ES (1) ES2670927T3 (US08106184-20120131-C00054.png)
WO (1) WO2007061798A2 (US08106184-20120131-C00054.png)

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US20160310517A1 (en) 2016-10-27
US9321797B2 (en) 2016-04-26
US9000147B2 (en) 2015-04-07
CN101360421A (zh) 2009-02-04
US10668096B2 (en) 2020-06-02
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US20200289535A1 (en) 2020-09-17
US8106184B2 (en) 2012-01-31
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