CN101141981A - Her抗体的固定剂量给药 - Google Patents

Her抗体的固定剂量给药 Download PDF

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Publication number
CN101141981A
CN101141981A CNA200580049191XA CN200580049191A CN101141981A CN 101141981 A CN101141981 A CN 101141981A CN A200580049191X A CNA200580049191X A CN A200580049191XA CN 200580049191 A CN200580049191 A CN 200580049191A CN 101141981 A CN101141981 A CN 101141981A
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China
Prior art keywords
antibody
cancer
antibodies
her2
pertuzumab
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Pending
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CNA200580049191XA
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English (en)
Chinese (zh)
Inventor
戴维·E·艾利森
勒内·布鲁诺
卢建丰
奇·M·恩格
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Genentech Inc
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Genentech Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35976673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101141981(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Priority to CN201210006776.5A priority Critical patent/CN102580084B/zh
Publication of CN101141981A publication Critical patent/CN101141981A/zh
Pending legal-status Critical Current

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C07ORGANIC CHEMISTRY
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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    • C07ORGANIC CHEMISTRY
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07ORGANIC CHEMISTRY
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/13Hollow or container type article [e.g., tube, vase, etc.]

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  • Gastroenterology & Hepatology (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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CNA200580049191XA 2005-01-21 2005-06-15 Her抗体的固定剂量给药 Pending CN101141981A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201210006776.5A CN102580084B (zh) 2005-01-21 2005-06-15 Her抗体的固定剂量给药

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64569705P 2005-01-21 2005-01-21
US60/645,697 2005-01-21

Related Child Applications (1)

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CN201210006776.5A Division CN102580084B (zh) 2005-01-21 2005-06-15 Her抗体的固定剂量给药

Publications (1)

Publication Number Publication Date
CN101141981A true CN101141981A (zh) 2008-03-12

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ID=35976673

Family Applications (2)

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CN201210006776.5A Ceased CN102580084B (zh) 2005-01-21 2005-06-15 Her抗体的固定剂量给药
CNA200580049191XA Pending CN101141981A (zh) 2005-01-21 2005-06-15 Her抗体的固定剂量给药

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CN201210006776.5A Ceased CN102580084B (zh) 2005-01-21 2005-06-15 Her抗体的固定剂量给药

Country Status (23)

Country Link
US (8) US7449184B2 (OSRAM)
EP (2) EP1846030B1 (OSRAM)
JP (3) JP2008528486A (OSRAM)
KR (8) KR20200058588A (OSRAM)
CN (2) CN102580084B (OSRAM)
AR (1) AR050418A1 (OSRAM)
AU (1) AU2005325200A1 (OSRAM)
BR (1) BRPI0518104B8 (OSRAM)
CA (1) CA2592177A1 (OSRAM)
CR (1) CR9253A (OSRAM)
ES (1) ES2710439T3 (OSRAM)
IL (3) IL184244A0 (OSRAM)
MA (1) MA29369B1 (OSRAM)
MX (1) MX2007008768A (OSRAM)
NO (1) NO20074238L (OSRAM)
NZ (1) NZ556095A (OSRAM)
PL (1) PL1846030T3 (OSRAM)
RU (1) RU2438705C2 (OSRAM)
TR (1) TR201901841T4 (OSRAM)
TW (1) TWI441646B (OSRAM)
UA (1) UA94899C2 (OSRAM)
WO (1) WO2006078307A1 (OSRAM)
ZA (1) ZA200706017B (OSRAM)

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