CN101054344B - 脂氧素a4类似物 - Google Patents
脂氧素a4类似物 Download PDFInfo
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- CN101054344B CN101054344B CN2007101081453A CN200710108145A CN101054344B CN 101054344 B CN101054344 B CN 101054344B CN 2007101081453 A CN2007101081453 A CN 2007101081453A CN 200710108145 A CN200710108145 A CN 200710108145A CN 101054344 B CN101054344 B CN 101054344B
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- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
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- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
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Abstract
Description
Claims (7)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33868401P | 2001-11-06 | 2001-11-06 | |
US60/338,684 | 2001-11-06 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA028268539A Division CN1612852A (zh) | 2001-11-06 | 2002-11-05 | 脂氧素a4类似物 |
Publications (2)
Publication Number | Publication Date |
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CN101054344A CN101054344A (zh) | 2007-10-17 |
CN101054344B true CN101054344B (zh) | 2011-12-07 |
Family
ID=23325714
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CN2007101081453A Expired - Fee Related CN101054344B (zh) | 2001-11-06 | 2002-11-05 | 脂氧素a4类似物 |
CNA028268539A Pending CN1612852A (zh) | 2001-11-06 | 2002-11-05 | 脂氧素a4类似物 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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CNA028268539A Pending CN1612852A (zh) | 2001-11-06 | 2002-11-05 | 脂氧素a4类似物 |
Country Status (31)
Country | Link |
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US (4) | US6831186B2 (zh) |
EP (1) | EP1472209B1 (zh) |
JP (4) | JP2005508380A (zh) |
KR (1) | KR100958216B1 (zh) |
CN (2) | CN101054344B (zh) |
AR (1) | AR037252A1 (zh) |
AT (1) | ATE424380T1 (zh) |
AU (1) | AU2002348167B2 (zh) |
BR (1) | BR0213940A (zh) |
CA (3) | CA2466418C (zh) |
CO (1) | CO5580762A2 (zh) |
CY (1) | CY1110472T1 (zh) |
DE (1) | DE60231435D1 (zh) |
DK (1) | DK1472209T3 (zh) |
EC (1) | ECSP085137A (zh) |
ES (1) | ES2323769T3 (zh) |
HK (1) | HK1109390A1 (zh) |
IL (2) | IL161811A0 (zh) |
MX (1) | MXPA04004300A (zh) |
NO (1) | NO329004B1 (zh) |
NZ (1) | NZ532672A (zh) |
PE (1) | PE20030566A1 (zh) |
PL (1) | PL207597B1 (zh) |
PT (1) | PT1472209E (zh) |
RS (1) | RS51005B (zh) |
RU (1) | RU2382026C2 (zh) |
SI (1) | SI1472209T1 (zh) |
TW (1) | TWI331992B (zh) |
UY (1) | UY27531A1 (zh) |
WO (1) | WO2003040080A2 (zh) |
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TW200816991A (en) * | 2006-08-23 | 2008-04-16 | Bayer Schering Pharma Ag | Treatment and prevention of intestinal fibrosis |
WO2008042216A2 (en) * | 2006-09-28 | 2008-04-10 | Follica, Inc. | Methods, kits, and compositions for generating new hair follicles and growing hair |
BRPI0718540A2 (pt) * | 2006-11-07 | 2013-11-19 | Alcon Res Ltd | Método de tratamento de asma, rinite alérgica, e distúrbios de pele |
US20090036530A1 (en) * | 2006-12-04 | 2009-02-05 | Bayer Schering Pharma Aktiengesellschaft | Crystalline acid of lipoxin A4 analogs and method of making |
PE20081571A1 (es) * | 2006-12-04 | 2009-01-04 | Bayer Schering Pharma Ag | Acido cristalino de analogos de lipoxina a4 y metodos de prepararlo |
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US20100278784A1 (en) * | 2007-05-15 | 2010-11-04 | Puretech Ventures | Methods and compositions for treating skin conditions |
EP2207543A2 (en) * | 2007-09-14 | 2010-07-21 | Resolvyx Pharmaceuticals, Inc. | Omega-3 fatty acids, hydroxy polyunsaturated fatty acids, lipoxin compounds, or oxylipin compounds for treating autoimmune diseases or inhibiting immune function |
US20100324138A1 (en) * | 2007-10-29 | 2010-12-23 | Bazan Nicolas G | Lipoxin A4 Protection for Retinal Cells |
US8729128B2 (en) * | 2007-10-30 | 2014-05-20 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Lipoxin A4 protection for cornea endothelial cells |
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TW201039815A (en) * | 2009-04-13 | 2010-11-16 | Resolvyx Pharmaceuticals Inc | Compositions and methods for the treatment of inflammation |
US10600073B2 (en) * | 2010-03-24 | 2020-03-24 | Innovid Inc. | System and method for tracking the performance of advertisements and predicting future behavior of the advertisement |
CA2819859A1 (en) | 2010-12-06 | 2012-06-14 | Follica, Inc. | Methods for treating baldness and promoting hair growth |
JP6228975B2 (ja) * | 2012-07-13 | 2017-11-08 | ソルヴェイ(ソシエテ アノニム) | 三重結合を有するフッ化カルボニル化合物、その製造方法、及びその使用 |
WO2018144316A1 (en) | 2017-01-31 | 2018-08-09 | The Brigham And Women's Hospital, Inc. | Alx receptor ligands define a biochemical endotype for inflammation-based diseases |
US20210401798A1 (en) * | 2018-10-23 | 2021-12-30 | The Brigham And Women's Hospital, Inc. | Lipoxin a4 analogs and uses thereof |
KR102086298B1 (ko) * | 2019-10-15 | 2020-03-06 | 건국대학교 산학협력단 | 리폭시게나아제 조합반응에 의한 리폭신 유사체의 제조방법 및 이로부터 제조된 리폭신 유사체 |
CN114890978B (zh) * | 2022-04-19 | 2023-07-25 | 宿迁医美科技有限公司 | 酚类化合物及其制备方法和应用 |
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US5650435A (en) | 1991-04-01 | 1997-07-22 | Madara; James L. | Modulation of inflammation related to columnar epithelia |
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AU7215294A (en) | 1993-06-29 | 1995-01-24 | Brigham And Women's Hospital | Modulation of inflammation related to columnar epithelia |
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WO2000054761A2 (en) | 1999-03-18 | 2000-09-21 | Brigham And Women's Hospital | Regulation of phospholipase d activity |
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Patent Citations (3)
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US5648512A (en) * | 1993-06-15 | 1997-07-15 | Brigham & Womens Hospital | Lipoxin compounds |
US6048897A (en) * | 1993-06-15 | 2000-04-11 | Brigham And Women's Hospital | Lipoxin compounds and their use in treating cell proliferative disorders |
US6433202B1 (en) * | 1999-03-18 | 2002-08-13 | Brigham And Women's Hospital | Prevention of neutrophil recruitment |
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