CN100475207C - 治疗蛋白激酶依赖性疾病的1H-咪唑并[4,5-c]喹啉衍生物 - Google Patents

治疗蛋白激酶依赖性疾病的1H-咪唑并[4,5-c]喹啉衍生物 Download PDF

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Publication number
CN100475207C
CN100475207C CNB038117053A CN03811705A CN100475207C CN 100475207 C CN100475207 C CN 100475207C CN B038117053 A CNB038117053 A CN B038117053A CN 03811705 A CN03811705 A CN 03811705A CN 100475207 C CN100475207 C CN 100475207C
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China
Prior art keywords
phenyl
chloro
quinoline
imidazo
imidazol
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Expired - Fee Related
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CNB038117053A
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Chinese (zh)
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CN1655788A (zh
Inventor
C·加西亚-埃切夫-埃里亚
H-G·卡普拉罗
P·菲雷
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Novartis AG
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Novartis AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CNB038117053A 2002-05-21 2003-05-20 治疗蛋白激酶依赖性疾病的1H-咪唑并[4,5-c]喹啉衍生物 Expired - Fee Related CN100475207C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0211649.9A GB0211649D0 (en) 2002-05-21 2002-05-21 Organic compounds
GB0211649.9 2002-05-21

Publications (2)

Publication Number Publication Date
CN1655788A CN1655788A (zh) 2005-08-17
CN100475207C true CN100475207C (zh) 2009-04-08

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CNB038117053A Expired - Fee Related CN100475207C (zh) 2002-05-21 2003-05-20 治疗蛋白激酶依赖性疾病的1H-咪唑并[4,5-c]喹啉衍生物

Country Status (15)

Country Link
US (1) US7998972B2 (enExample)
EP (1) EP1509521B8 (enExample)
JP (1) JP4707389B2 (enExample)
CN (1) CN100475207C (enExample)
AT (1) ATE405564T1 (enExample)
AU (1) AU2003240680A1 (enExample)
BR (1) BR0311221A (enExample)
CA (1) CA2485012A1 (enExample)
DE (1) DE60323090D1 (enExample)
DK (1) DK1509521T3 (enExample)
ES (1) ES2312783T3 (enExample)
GB (1) GB0211649D0 (enExample)
PT (1) PT1509521E (enExample)
SI (1) SI1509521T1 (enExample)
WO (1) WO2003097641A2 (enExample)

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