CN100463921C - 白蛋白纯化 - Google Patents
白蛋白纯化 Download PDFInfo
- Publication number
- CN100463921C CN100463921C CNB031235026A CN03123502A CN100463921C CN 100463921 C CN100463921 C CN 100463921C CN B031235026 A CNB031235026 A CN B031235026A CN 03123502 A CN03123502 A CN 03123502A CN 100463921 C CN100463921 C CN 100463921C
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- CN
- China
- Prior art keywords
- medium
- aglucon
- fermented liquid
- rhsa
- hydrophobic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- OUUQCZGPVNCOIJ-UHFFFAOYSA-N hydroperoxyl Chemical group O[O] OUUQCZGPVNCOIJ-UHFFFAOYSA-N 0.000 description 1
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- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE02015188 | 2002-05-15 | ||
| SE0201518A SE526227C2 (sv) | 2002-05-15 | 2002-05-15 | Metod för rening av rekombinant humant serumalbumin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1496993A CN1496993A (zh) | 2004-05-19 |
| CN100463921C true CN100463921C (zh) | 2009-02-25 |
Family
ID=20287916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031235026A Expired - Fee Related CN100463921C (zh) | 2002-05-15 | 2003-05-09 | 白蛋白纯化 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7423124B2 (https=) |
| EP (2) | EP1504031B1 (https=) |
| JP (2) | JP2006502098A (https=) |
| CN (1) | CN100463921C (https=) |
| AT (1) | ATE335006T1 (https=) |
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| DE (1) | DE60307262T2 (https=) |
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| CN1756587A (zh) * | 2003-03-12 | 2006-04-05 | 弗雷泽纽斯卡比德国有限公司 | 重组白蛋白在肝衰竭后透析中的用途 |
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| CN1854155B (zh) * | 2005-04-29 | 2010-11-17 | 华北制药集团新药研究开发有限责任公司 | 一种纯化rHSA的方法 |
| CL2008002053A1 (es) | 2007-07-17 | 2009-05-22 | Hoffmann La Roche | Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion. |
| AR067536A1 (es) * | 2007-07-17 | 2009-10-14 | Hoffmann La Roche | Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea |
| EP2261661A4 (en) * | 2008-03-31 | 2011-04-20 | Sekisui Medical Co Ltd | CLEANED SERUM ALBUMIN AND IMMUNOLOGY MEASUREMENT PROCESS |
| US8753868B2 (en) * | 2008-08-04 | 2014-06-17 | General Electric Company | Method and system for selective isolation of target biological molecules in a general purpose system |
| CN101768206B (zh) * | 2008-12-31 | 2013-05-15 | 华北制药集团新药研究开发有限责任公司 | 一种重组人血清白蛋白的纯化方法及其应用 |
| JP2012518409A (ja) | 2009-02-20 | 2012-08-16 | ベントリア・バイオサイエンス | タンパク質の組み合わせを含有する細胞培養培地 |
| KR101976853B1 (ko) | 2010-05-25 | 2019-05-09 | 제넨테크, 인크. | 폴리펩티드의 정제 방법 |
| CN102127164B (zh) | 2010-12-20 | 2013-01-30 | 武汉禾元生物科技有限公司 | 一种从水稻种子中提取重组人血清白蛋白的方法 |
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| EP3307876B1 (en) | 2015-06-10 | 2023-09-13 | ImmunityBio, Inc. | Modified nk-92 cells for treating cancer |
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| CN106117347A (zh) * | 2015-12-09 | 2016-11-16 | 烟台大学 | 一种疏水层析制备高纯度藻红蛋白的方法 |
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| WO2021061790A1 (en) * | 2019-09-24 | 2021-04-01 | Regeneron Pharmaceuticals, Inc. | Systems and methods for chromatography use and regeneration |
| US12161777B2 (en) | 2020-07-02 | 2024-12-10 | Davol Inc. | Flowable hemostatic suspension |
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| KR20230060524A (ko) | 2020-12-08 | 2023-05-04 | 통화 안레이트 바이오파마슈티컬 컴퍼니 리미티드 | 재조합 단백질의 정제 방법 |
| JP2024500994A (ja) | 2020-12-28 | 2024-01-10 | デボル，インコーポレイテッド | タンパク質及び多官能化変性ポリエチレングリコール系架橋剤を含む反応性乾燥粉末状止血用材料 |
| CN113461804A (zh) * | 2021-08-09 | 2021-10-01 | 山东健通生物科技有限公司 | 减少重组人血白蛋白发酵过程中色素的方法 |
| CN113880908B (zh) * | 2021-08-25 | 2024-05-14 | 北京伟德杰生物科技有限公司 | 纯化重组人血清白蛋白的融合蛋白的方法 |
| CN113735962B (zh) * | 2021-08-27 | 2023-11-10 | 常熟纳微生物科技有限公司 | 一种从猪血中纯化重组人血清白蛋白的方法及应用 |
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| FR2403098A1 (fr) | 1977-09-19 | 1979-04-13 | Merieux Inst | Nouveau materiau capable de fixer de facon reversible des macromolecules biologiques, sa preparation et son application |
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| US5986062A (en) * | 1992-05-20 | 1999-11-16 | The Green Cross Corporation | Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same |
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| US20050215765A1 (en) | 2005-09-29 |
| DE60307262T2 (de) | 2007-06-28 |
| JP2006512283A (ja) | 2006-04-13 |
| SE526227C2 (sv) | 2005-08-02 |
| SE0201518D0 (sv) | 2002-05-15 |
| ES2268362T3 (es) | 2007-03-16 |
| WO2003097693A1 (en) | 2003-11-27 |
| IL164844A (en) | 2009-09-01 |
| IL164844A0 (en) | 2005-12-18 |
| JP2006502098A (ja) | 2006-01-19 |
| US7351801B2 (en) | 2008-04-01 |
| CA2483616A1 (en) | 2003-11-27 |
| CA2483612A1 (en) | 2003-11-27 |
| BR0309992A (pt) | 2005-03-01 |
| BRPI0309992B1 (pt) | 2020-12-22 |
| US20050214902A1 (en) | 2005-09-29 |
| BRPI0309992B8 (pt) | 2023-03-21 |
| AU2003232704A1 (en) | 2003-12-02 |
| AU2003228193A1 (en) | 2003-12-02 |
| DE60307262D1 (de) | 2006-09-14 |
| JP4559216B2 (ja) | 2010-10-06 |
| EP1504032A1 (en) | 2005-02-09 |
| CN1496993A (zh) | 2004-05-19 |
| WO2003097692A1 (en) | 2003-11-27 |
| AU2003228193B2 (en) | 2009-05-07 |
| US7423124B2 (en) | 2008-09-09 |
| EP1504031A1 (en) | 2005-02-09 |
| EP1504031B1 (en) | 2006-08-02 |
| ATE335006T1 (de) | 2006-08-15 |
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